Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)- cells

Diabetologia

Volumn 42, Issue 7, 1999, Pages 856-864

  Buteau, J ^a   Roduit, R ^a   Susini, S ^b   Prentki, M ^a,c  

^a UNIVERSITY OF MONTREAL   (Canada)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

AP 1; Cell growth; DNA synthesis; Glucagon like peptide 1; Glucose; Insulin secretion; Pancreatic beta cell; PDX 1; Phosphatidylinositol 3 kinase

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; DNA; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; GLUCOSE TRANSPORTER; GROWTH FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; THYMIDINE; TRANSCRIPTION FACTOR; TRITIUM; WORTMANNIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA BINDING; DNA SYNTHESIS; ENZYME ACTIVATION; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HOMEOBOX; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMALS; CHROMONES; DNA; DNA-BINDING PROTEINS; DUODENUM; ENZYME ACTIVATION; ENZYME INHIBITORS; GENES, HOMEOBOX; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE; HUMANS; INSULIN; ISLETS OF LANGERHANS; MORPHOLINES; NIFEDIPINE; PANCREAS; PEPTIDE FRAGMENTS; POTASSIUM CHLORIDE; PROTEIN PRECURSORS; RATS; RATS, WISTAR; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0032768616     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051238     Document Type: Article

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