메뉴 건너뛰기




Volumn 356, Issue 1, 2015, Pages 137-144

Radiation-induced bystander effect: Early process and rapid assessment

Author keywords

Early process; Radiation induced bystander effect; Rapid assessment

Indexed keywords

ATM PROTEIN; CD59 ANTIGEN; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLINE; HISTONE H2AX; MITOCHONDRIAL DNA; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TUMOR SUPPRESSOR P53 BINDING PROTEIN 1; UNCLASSIFIED DRUG; ATM PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; H2AFX PROTEIN, HUMAN; HISTONE; SIGNAL PEPTIDE; TP53BP1 PROTEIN, HUMAN;

EID: 84912562120     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2013.09.031     Document Type: Review
Times cited : (57)

References (81)
  • 1
    • 0034581090 scopus 로고    scopus 로고
    • Radiation, the two-edged sword: cancer risks at high and low doses
    • Hall E.J. Radiation, the two-edged sword: cancer risks at high and low doses. Cancer J. 2000, 6:343-350.
    • (2000) Cancer J. , vol.6 , pp. 343-350
    • Hall, E.J.1
  • 2
    • 0042068170 scopus 로고    scopus 로고
    • Radiation: a dose of the bomb
    • Little M.P. Radiation: a dose of the bomb. Nature 2003, 424:495-496.
    • (2003) Nature , vol.424 , pp. 495-496
    • Little, M.P.1
  • 3
    • 0026454677 scopus 로고
    • Induction of sister chromatid exchanges by extremely low doses of α-particles
    • Nagasawa H., Little J.B. Induction of sister chromatid exchanges by extremely low doses of α-particles. Cancer Res. 1992, 52:6394-6396.
    • (1992) Cancer Res. , vol.52 , pp. 6394-6396
    • Nagasawa, H.1    Little, J.B.2
  • 4
    • 0032518596 scopus 로고    scopus 로고
    • Partial volume rat lung irradiation: an evaluation of early DNA damage
    • Khan M.A., Hill R.P., Van Dyk J. Partial volume rat lung irradiation: an evaluation of early DNA damage. Int. J. Radiat. Oncol. Biol. Phys. 1998, 40:467.
    • (1998) Int. J. Radiat. Oncol. Biol. Phys. , vol.40 , pp. 467
    • Khan, M.A.1    Hill, R.P.2    Van Dyk, J.3
  • 5
    • 0031674026 scopus 로고    scopus 로고
    • Studies of bystander effects in human fibroblasts using a charged particle microbeam
    • Prise K. Studies of bystander effects in human fibroblasts using a charged particle microbeam. Int. J. Radiat. Biol. 1998, 74:793-798.
    • (1998) Int. J. Radiat. Biol. , vol.74 , pp. 793-798
    • Prise, K.1
  • 6
    • 0035895240 scopus 로고    scopus 로고
    • Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from α-particle irradiated to nonirradiated cells
    • Azzam E.I., De Toledo S.M., Little J.B. Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from α-particle irradiated to nonirradiated cells. Proc. Natl. Acad. Sci. USA 2001, 98:473-478.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 473-478
    • Azzam, E.I.1    De Toledo, S.M.2    Little, J.B.3
  • 8
    • 0036675428 scopus 로고    scopus 로고
    • Radiation-induced effects in unirradiated cells: a review and implications in cancer
    • Goldberg Z., Lehnert B.E. Radiation-induced effects in unirradiated cells: a review and implications in cancer. Int. J. Oncol. 2002, 21:337-350.
    • (2002) Int. J. Oncol. , vol.21 , pp. 337-350
    • Goldberg, Z.1    Lehnert, B.E.2
  • 9
    • 64649084383 scopus 로고    scopus 로고
    • Radiation-induced bystander signalling in cancer therapy
    • Prise K.M., O'Sullivan J.M. Radiation-induced bystander signalling in cancer therapy. Nat. Rev. Cancer 2009, 9:351-360.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 351-360
    • Prise, K.M.1    O'Sullivan, J.M.2
  • 10
    • 0037171647 scopus 로고    scopus 로고
    • Cellular communication and bystander effects: a critical review for modelling low-dose radiation action
    • Ballarini F., Biaggi M., Ottolenghi A., Sapora O. Cellular communication and bystander effects: a critical review for modelling low-dose radiation action. Mutat. Res. 2002, 501:1-12.
    • (2002) Mutat. Res. , vol.501 , pp. 1-12
    • Ballarini, F.1    Biaggi, M.2    Ottolenghi, A.3    Sapora, O.4
  • 11
    • 33646052257 scopus 로고    scopus 로고
    • Cellular radiation effects and the bystander response
    • Little J.B. Cellular radiation effects and the bystander response. Mutat. Res. 2006, 597:113-118.
    • (2006) Mutat. Res. , vol.597 , pp. 113-118
    • Little, J.B.1
  • 12
    • 79953797588 scopus 로고    scopus 로고
    • Emerging role of radiation induced bystander effects: cell communications and carcinogenesis
    • Baskar R. Emerging role of radiation induced bystander effects: cell communications and carcinogenesis. Genome Integrity 2010, 1:13.
    • (2010) Genome Integrity , vol.1 , pp. 13
    • Baskar, R.1
  • 13
    • 33846834182 scopus 로고    scopus 로고
    • Non-targeted bystander effects induced by ionizing radiation
    • MorganM W.F., Sowa B. Non-targeted bystander effects induced by ionizing radiation. Mutat. Res. 2007, 616:159-164.
    • (2007) Mutat. Res. , vol.616 , pp. 159-164
    • MorganM, W.F.1    Sowa, B.2
  • 14
    • 33744997893 scopus 로고    scopus 로고
    • Cyclooxygenase-2 as a signaling molecule in radiation-induced bystander effect
    • Hei T.K. Cyclooxygenase-2 as a signaling molecule in radiation-induced bystander effect. Mol. Carcinogen. 2006, 45:455-460.
    • (2006) Mol. Carcinogen. , vol.45 , pp. 455-460
    • Hei, T.K.1
  • 16
    • 84255167552 scopus 로고    scopus 로고
    • The disaster at Japan's Fukushima-Daiichi nuclear power plant after the March 11, 2011 earthquake and tsunami, and the resulting spread of radioisotope contamination
    • Ohnishi T. The disaster at Japan's Fukushima-Daiichi nuclear power plant after the March 11, 2011 earthquake and tsunami, and the resulting spread of radioisotope contamination. Radiat. Res. 2011, 177(2012):1-14.
    • (2011) Radiat. Res. , vol.177 , Issue.2012 , pp. 1-14
    • Ohnishi, T.1
  • 17
    • 0037628777 scopus 로고    scopus 로고
    • Low-dose radiation: thresholds, bystander effects, and adaptive responses
    • Bonner W.M. Low-dose radiation: thresholds, bystander effects, and adaptive responses. Proc. Natl. Acad. Sci. USA 2003, 100:4973-4975.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 4973-4975
    • Bonner, W.M.1
  • 19
    • 82955205849 scopus 로고    scopus 로고
    • Effects of very low fluences of high-energy protons or iron ions on irradiated and bystander cells
    • Yang H., Magpayo N., Rusek A., Chiang I.H., SivertzK M., Held D. Effects of very low fluences of high-energy protons or iron ions on irradiated and bystander cells. Radiat. Res. 2011, 176:695-705.
    • (2011) Radiat. Res. , vol.176 , pp. 695-705
    • Yang, H.1    Magpayo, N.2    Rusek, A.3    Chiang, I.H.4    SivertzK, M.5    Held, D.6
  • 20
    • 0034759199 scopus 로고    scopus 로고
    • HPRT mutants induced in bystander cells by very low fluences of alpha particles result primarily from point mutations
    • Huo L., Nagasawa H., Little J.B. HPRT mutants induced in bystander cells by very low fluences of alpha particles result primarily from point mutations. Radiat. Res. 2001, 156:521-525.
    • (2001) Radiat. Res. , vol.156 , pp. 521-525
    • Huo, L.1    Nagasawa, H.2    Little, J.B.3
  • 21
    • 0036569926 scopus 로고    scopus 로고
    • Involvement of membrane signaling in the bystander effect in irradiated cells
    • Nagasawa H., Cremesti A., Kolesnick R., Fuks Z., Little J.B. Involvement of membrane signaling in the bystander effect in irradiated cells. Cancer Res. 2002, 62:2531-2534.
    • (2002) Cancer Res. , vol.62 , pp. 2531-2534
    • Nagasawa, H.1    Cremesti, A.2    Kolesnick, R.3    Fuks, Z.4    Little, J.B.5
  • 23
    • 51649119854 scopus 로고    scopus 로고
    • DNA double-strand breaks induced by very low X-ray doses are largely due to bystander effects
    • Ojima M., Ban N., Kai M. DNA double-strand breaks induced by very low X-ray doses are largely due to bystander effects. Radiat. Res. 2009, 365-371.
    • (2009) Radiat. Res. , pp. 365-371
    • Ojima, M.1    Ban, N.2    Kai, M.3
  • 24
    • 31544478262 scopus 로고    scopus 로고
    • The time and spatial effects of bystander response in mammalian cells induced by low dose radiation
    • Hu B., Wu L., Han W., Zhang L., Chen S., Xu A., Hei T.K., Yu Z. The time and spatial effects of bystander response in mammalian cells induced by low dose radiation. Carcinogenesis 2006, 27:245-251.
    • (2006) Carcinogenesis , vol.27 , pp. 245-251
    • Hu, B.1    Wu, L.2    Han, W.3    Zhang, L.4    Chen, S.5    Xu, A.6    Hei, T.K.7    Yu, Z.8
  • 25
    • 34948856309 scopus 로고    scopus 로고
    • The early and initiation processes of radiation-induced bystander effects involved in the induction of DNA double strand breaks in non-irradiated cultures
    • Han W., Wu L., Hu B., Zhang L., Chen S., Bao L., Zhao Y., Yu A.XuZ. The early and initiation processes of radiation-induced bystander effects involved in the induction of DNA double strand breaks in non-irradiated cultures. Br. J. Radiol. 2007, 80:S7-S12.
    • (2007) Br. J. Radiol. , vol.80 , pp. S7-S12
    • Han, W.1    Wu, L.2    Hu, B.3    Zhang, L.4    Chen, S.5    Bao, L.6    Zhao, Y.7    Yu, A.8
  • 26
    • 0035289717 scopus 로고    scopus 로고
    • Chromosomal stability and the DNA double-stranded break connection
    • van Gent D.C., Hoeijmakers J.H., Kanaar R. Chromosomal stability and the DNA double-stranded break connection. Nat. Rev. Genet. 2001, 2:196-206.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 196-206
    • van Gent, D.C.1    Hoeijmakers, J.H.2    Kanaar, R.3
  • 27
    • 33750692709 scopus 로고    scopus 로고
    • γ-H2AX and its role in DNA double-strand break repair
    • Fillingham J., Keogh M.C., Krogan N.J. γ-H2AX and its role in DNA double-strand break repair. Biochem. Cell. Biol. 2006, 84:568-577.
    • (2006) Biochem. Cell. Biol. , vol.84 , pp. 568-577
    • Fillingham, J.1    Keogh, M.C.2    Krogan, N.J.3
  • 28
    • 0037206597 scopus 로고    scopus 로고
    • Bystander effect for chromosomal aberrations induced in wild-type and repair deficient CHO cells by low fluences of alpha particles
    • Nagasawa H., Little J.B. Bystander effect for chromosomal aberrations induced in wild-type and repair deficient CHO cells by low fluences of alpha particles. Mutat. Res. 2002, 508:121-129.
    • (2002) Mutat. Res. , vol.508 , pp. 121-129
    • Nagasawa, H.1    Little, J.B.2
  • 29
    • 0037316976 scopus 로고    scopus 로고
    • Involvement of the nonhomologous end joining DNA repair pathway in the bystander effect for chromosomal aberrations
    • Little J.B., Nagasawa H., Li G.C., Chen D.J. Involvement of the nonhomologous end joining DNA repair pathway in the bystander effect for chromosomal aberrations. Radiat. Res. 2003, 159:262-267.
    • (2003) Radiat. Res. , vol.159 , pp. 262-267
    • Little, J.B.1    Nagasawa, H.2    Li, G.C.3    Chen, D.J.4
  • 30
    • 0037247668 scopus 로고    scopus 로고
    • Increased bystander mutagenic effect in DNA double-strand break repair-deficient mammalian cells
    • Nagasawa H., Huo L., Little J. Increased bystander mutagenic effect in DNA double-strand break repair-deficient mammalian cells. Int. J. Radiat. Biol. 2003, 79:35-41.
    • (2003) Int. J. Radiat. Biol. , vol.79 , pp. 35-41
    • Nagasawa, H.1    Huo, L.2    Little, J.3
  • 31
    • 38049155945 scopus 로고    scopus 로고
    • Regulation of DNA double-strand break repair pathway choice
    • Shrivastav M., De Haro L.P., Nickoloff J.A. Regulation of DNA double-strand break repair pathway choice. Cell Res. 2007, 18:134-147.
    • (2007) Cell Res. , vol.18 , pp. 134-147
    • Shrivastav, M.1    De Haro, L.P.2    Nickoloff, J.A.3
  • 32
    • 33845604556 scopus 로고    scopus 로고
    • DNA double-strand break repair: all's well that ends well
    • Wyman C., Kanaar R. DNA double-strand break repair: all's well that ends well. Annu. Rev. Genet. 2006, 40:363-383.
    • (2006) Annu. Rev. Genet. , vol.40 , pp. 363-383
    • Wyman, C.1    Kanaar, R.2
  • 34
    • 16444382297 scopus 로고    scopus 로고
    • Medium-mediated intercellular communication is involved in bystander responses of X-ray-irradiated normal human fibroblasts
    • Yang H., Asaad N., Held K.D. Medium-mediated intercellular communication is involved in bystander responses of X-ray-irradiated normal human fibroblasts. Oncogene 2005, 24:2096-2103.
    • (2005) Oncogene , vol.24 , pp. 2096-2103
    • Yang, H.1    Asaad, N.2    Held, K.D.3
  • 36
    • 24144467509 scopus 로고    scopus 로고
    • In situ visualization of DSBs to assess the extranuclear/extracellular effects induced by low-dose α-particle irradiation
    • Hu B., Han W., Wu L., Feng H., Liu X., Zhang L., Xu A., Hei T., Yu Z. In situ visualization of DSBs to assess the extranuclear/extracellular effects induced by low-dose α-particle irradiation. Radiat. Res. 2005, 164:286-291.
    • (2005) Radiat. Res. , vol.164 , pp. 286-291
    • Hu, B.1    Han, W.2    Wu, L.3    Feng, H.4    Liu, X.5    Zhang, L.6    Xu, A.7    Hei, T.8    Yu, Z.9
  • 37
    • 35148834590 scopus 로고    scopus 로고
    • γ-H2AX in bystander cells: not just a radiation-triggered event, a cellular response to stress mediated by intercellular communication
    • Sokolov M.V., Dickey J.S., Bonner W.M., Martin O.A. γ-H2AX in bystander cells: not just a radiation-triggered event, a cellular response to stress mediated by intercellular communication. Cell Cycle 2007, 6:2210-2212.
    • (2007) Cell Cycle , vol.6 , pp. 2210-2212
    • Sokolov, M.V.1    Dickey, J.S.2    Bonner, W.M.3    Martin, O.A.4
  • 39
    • 80053109692 scopus 로고    scopus 로고
    • Gamma-H2AX-based dose estimation for whole and partial body radiation exposure
    • Horn S., Barnard S., Rothkamm K. Gamma-H2AX-based dose estimation for whole and partial body radiation exposure. PloS One 2011, 6:e25113.
    • (2011) PloS One , vol.6 , pp. e25113
    • Horn, S.1    Barnard, S.2    Rothkamm, K.3
  • 40
    • 77951296831 scopus 로고    scopus 로고
    • Medium-mediated DNA repair response after ionizing radiation is correlated with the increase of specific cytokines in human fibroblasts
    • Dieriks B., De Vos W.H., Derradji H., Baatout S., van Oostveldt P. Medium-mediated DNA repair response after ionizing radiation is correlated with the increase of specific cytokines in human fibroblasts. Mutat. Res. 2010, 687:40-48.
    • (2010) Mutat. Res. , vol.687 , pp. 40-48
    • Dieriks, B.1    De Vos, W.H.2    Derradji, H.3    Baatout, S.4    van Oostveldt, P.5
  • 41
    • 35348893818 scopus 로고    scopus 로고
    • Elevated sodium chloride concentrations enhance the bystander effects induced by low dose alpha-particle irradiation
    • Han W., Zhu L., Jiang E., Wang J., Chen S., Bao L., Zhao Y., Xu A., Yu Z., Wu L. Elevated sodium chloride concentrations enhance the bystander effects induced by low dose alpha-particle irradiation. Mutat. Res. 2007, 624:124-131.
    • (2007) Mutat. Res. , vol.624 , pp. 124-131
    • Han, W.1    Zhu, L.2    Jiang, E.3    Wang, J.4    Chen, S.5    Bao, L.6    Zhao, Y.7    Xu, A.8    Yu, Z.9    Wu, L.10
  • 42
    • 35348834232 scopus 로고    scopus 로고
    • The time dependence of bystander responses induced by iron-ion radiation in normal human skin fibroblasts
    • Yang H., Anzenberg V., Held K.D. The time dependence of bystander responses induced by iron-ion radiation in normal human skin fibroblasts. Radiat. Res. 2007, 168:292-298.
    • (2007) Radiat. Res. , vol.168 , pp. 292-298
    • Yang, H.1    Anzenberg, V.2    Held, K.D.3
  • 47
    • 34250879092 scopus 로고    scopus 로고
    • Cytoplasmic irradiation induces mitochondrial-dependent 53BP1 protein relocalization in irradiated and bystander cells
    • Tartier L., Gilchrist S., Burdak-Rothkamm S., Folkard M., Prise K.M. Cytoplasmic irradiation induces mitochondrial-dependent 53BP1 protein relocalization in irradiated and bystander cells. Cancer Res. 2007, 67:5872-5879.
    • (2007) Cancer Res. , vol.67 , pp. 5872-5879
    • Tartier, L.1    Gilchrist, S.2    Burdak-Rothkamm, S.3    Folkard, M.4    Prise, K.M.5
  • 48
    • 73949161269 scopus 로고    scopus 로고
    • Nitric oxide mediated DNA double strand breaks induced in proliferating bystander cells after α-particle irradiation
    • Han W., Chen S., Yu K., Wu L. Nitric oxide mediated DNA double strand breaks induced in proliferating bystander cells after α-particle irradiation. Mutat. Res. 2010, 684:81-89.
    • (2010) Mutat. Res. , vol.684 , pp. 81-89
    • Han, W.1    Chen, S.2    Yu, K.3    Wu, L.4
  • 49
    • 77649205680 scopus 로고    scopus 로고
    • Exogenous carbon monoxide protects the bystander Chinese hamster ovary cells in mixed coculture system after alpha-particle irradiation
    • Han W., Wu L., Chen S., Yu K.N. Exogenous carbon monoxide protects the bystander Chinese hamster ovary cells in mixed coculture system after alpha-particle irradiation. Carcinogenesis 2010, 31:275-280.
    • (2010) Carcinogenesis , vol.31 , pp. 275-280
    • Han, W.1    Wu, L.2    Chen, S.3    Yu, K.N.4
  • 50
    • 78649948605 scopus 로고    scopus 로고
    • Radiation-induced bystander effects in cultured human stem cells
    • Sokolov M.V., Neumann R.D. Radiation-induced bystander effects in cultured human stem cells. PloS One 2010, 5:e14195.
    • (2010) PloS One , vol.5 , pp. e14195
    • Sokolov, M.V.1    Neumann, R.D.2
  • 52
    • 52449114574 scopus 로고    scopus 로고
    • Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer
    • Lavin M.F. Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer. Nat. Rev. Mol. Cell. Biol. 2008, 9:759-769.
    • (2008) Nat. Rev. Mol. Cell. Biol. , vol.9 , pp. 759-769
    • Lavin, M.F.1
  • 53
    • 52049090123 scopus 로고    scopus 로고
    • ATM acts downstream of ATR in the DNA damage response signaling of bystander cells
    • Burdak-Rothkamm S., Rothkamm K., Prise K.M. ATM acts downstream of ATR in the DNA damage response signaling of bystander cells. Cancer Res. 2008, 68:7059-7065.
    • (2008) Cancer Res. , vol.68 , pp. 7059-7065
    • Burdak-Rothkamm, S.1    Rothkamm, K.2    Prise, K.M.3
  • 54
    • 78650587293 scopus 로고    scopus 로고
    • Persistence of DNA double-strand breaks in normal human cells induced by radiation-induced bystander effect
    • Ojima M., Furutani A., Ban N., Kai M. Persistence of DNA double-strand breaks in normal human cells induced by radiation-induced bystander effect. Radiat. Res. 2010, 175:90-96.
    • (2010) Radiat. Res. , vol.175 , pp. 90-96
    • Ojima, M.1    Furutani, A.2    Ban, N.3    Kai, M.4
  • 55
    • 67649424560 scopus 로고    scopus 로고
    • P21 in cancer: intricate networks and multiple activities
    • Abbas T., Dutta A. P21 in cancer: intricate networks and multiple activities. Nat. Rev. Cancer 2009, 9:400-414.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 400-414
    • Abbas, T.1    Dutta, A.2
  • 56
    • 0036791114 scopus 로고    scopus 로고
    • Oxidative metabolism modulates signal transduction and micronucleus formation in bystander cells from α-particle-irradiated normal human fibroblast cultures
    • Azzam E.I., De Toledo S.M., Spitz D.R., Little J.B. Oxidative metabolism modulates signal transduction and micronucleus formation in bystander cells from α-particle-irradiated normal human fibroblast cultures. Cancer Res. 2002, 62:5436-5442.
    • (2002) Cancer Res. , vol.62 , pp. 5436-5442
    • Azzam, E.I.1    De Toledo, S.M.2    Spitz, D.R.3    Little, J.B.4
  • 57
    • 33847034811 scopus 로고    scopus 로고
    • Radiation-induced bystander effect: activation of signaling molecules in K562 erythroleukemia cells
    • Mitra A.K., Krishna M. Radiation-induced bystander effect: activation of signaling molecules in K562 erythroleukemia cells. J. Cell Biochem. 2007, 100:991-997.
    • (2007) J. Cell Biochem. , vol.100 , pp. 991-997
    • Mitra, A.K.1    Krishna, M.2
  • 58
    • 67650660059 scopus 로고    scopus 로고
    • Propagation distance of the α-particle-induced bystander effect: the role of nuclear traversal and gap junction communication
    • Gaillard S., Pusset D., de Toledo S.M., Fromm M., Azzam E.I. Propagation distance of the α-particle-induced bystander effect: the role of nuclear traversal and gap junction communication. Radiat. Res. 2009, 171:513-520.
    • (2009) Radiat. Res. , vol.171 , pp. 513-520
    • Gaillard, S.1    Pusset, D.2    de Toledo, S.M.3    Fromm, M.4    Azzam, E.I.5
  • 59
    • 0031045565 scopus 로고    scopus 로고
    • PCNA: structure, functions and interactions
    • Kelman Z. PCNA: structure, functions and interactions. Oncogene 1997, 14:629-640.
    • (1997) Oncogene , vol.14 , pp. 629-640
    • Kelman, Z.1
  • 60
    • 0034161938 scopus 로고    scopus 로고
    • Factors underlying the cell growth-related bystander responses to α particles
    • Iyer R., Lehnert B.E. Factors underlying the cell growth-related bystander responses to α particles. Cancer Res. 2000, 60:1290-1298.
    • (2000) Cancer Res. , vol.60 , pp. 1290-1298
    • Iyer, R.1    Lehnert, B.E.2
  • 61
    • 11144303464 scopus 로고    scopus 로고
    • Bound PCNA in nuclei of primary rat tracheal epithelial cells after exposure to very low doses of plutonium-238 α particles
    • Hill M., Ford J., Clapham P., Marsden S., Stevens D., Townsend K.S., Goodhead D. Bound PCNA in nuclei of primary rat tracheal epithelial cells after exposure to very low doses of plutonium-238 α particles. Radiat. Res. 2005, 163:36-44.
    • (2005) Radiat. Res. , vol.163 , pp. 36-44
    • Hill, M.1    Ford, J.2    Clapham, P.3    Marsden, S.4    Stevens, D.5    Townsend, K.S.6    Goodhead, D.7
  • 62
    • 33846841032 scopus 로고    scopus 로고
    • Detection of oxidative clustered DNA lesions in X-irradiated mouse skin tissues and human MCF-7 breast cancer cells
    • Gollapalle E., Wang R., Adetolu R., Tsao D., Francisco D., Sigounas G., Georgakilas A.G. Detection of oxidative clustered DNA lesions in X-irradiated mouse skin tissues and human MCF-7 breast cancer cells. Radiat. Res. 2007, 167:207-216.
    • (2007) Radiat. Res. , vol.167 , pp. 207-216
    • Gollapalle, E.1    Wang, R.2    Adetolu, R.3    Tsao, D.4    Francisco, D.5    Sigounas, G.6    Georgakilas, A.G.7
  • 63
    • 84880544586 scopus 로고    scopus 로고
    • Induction and repair of clustered DNA lesions: what do we know so far?
    • Georgakilas A.G., O'Neill P., Stewart R.D. Induction and repair of clustered DNA lesions: what do we know so far?. Radiat. Res. 2013, 180:100-109.
    • (2013) Radiat. Res. , vol.180 , pp. 100-109
    • Georgakilas, A.G.1    O'Neill, P.2    Stewart, R.D.3
  • 64
    • 84856235426 scopus 로고    scopus 로고
    • Bystander normal human fibroblasts reduce damage response in radiation targeted cancer cells through intercellular ROS level modulation
    • Widel M., Przybyszewski W.M., Cieslar-Pobuda A., Saenko Y.V., Rzeszowska-Wolny J. Bystander normal human fibroblasts reduce damage response in radiation targeted cancer cells through intercellular ROS level modulation. Mutat. Res. 2012, 731:117-124.
    • (2012) Mutat. Res. , vol.731 , pp. 117-124
    • Widel, M.1    Przybyszewski, W.M.2    Cieslar-Pobuda, A.3    Saenko, Y.V.4    Rzeszowska-Wolny, J.5
  • 65
    • 70350303361 scopus 로고    scopus 로고
    • Ionizing radiation-induced bystander mutagenesis and adaptation: quantitative and temporal aspects
    • Zhang Y., Zhou J., Baldwin J., Held K.D., Prise K.M., Redmond R.W., Liber H.L. Ionizing radiation-induced bystander mutagenesis and adaptation: quantitative and temporal aspects. Mutat. Res. 2009, 671:20-25.
    • (2009) Mutat. Res. , vol.671 , pp. 20-25
    • Zhang, Y.1    Zhou, J.2    Baldwin, J.3    Held, K.D.4    Prise, K.M.5    Redmond, R.W.6    Liber, H.L.7
  • 66
    • 33645470116 scopus 로고    scopus 로고
    • The involvement of calcium and MAP kinase signaling pathways in the production of radiation-induced bystander effects
    • Lyng F.M., Maguire P., McClean B., Seymour C., Mothersill C. The involvement of calcium and MAP kinase signaling pathways in the production of radiation-induced bystander effects. Radiat. Res. 2006, 165:400-409.
    • (2006) Radiat. Res. , vol.165 , pp. 400-409
    • Lyng, F.M.1    Maguire, P.2    McClean, B.3    Seymour, C.4    Mothersill, C.5
  • 67
    • 33748474948 scopus 로고    scopus 로고
    • Calcium fluxes modulate the radiation-induced bystander responses in targeted glioma and fibroblast cells
    • Shao C., Lyng F.M., Folkard M., Prise K.M. Calcium fluxes modulate the radiation-induced bystander responses in targeted glioma and fibroblast cells. Radiat. Res. 2006, 166:479-487.
    • (2006) Radiat. Res. , vol.166 , pp. 479-487
    • Shao, C.1    Lyng, F.M.2    Folkard, M.3    Prise, K.M.4
  • 68
    • 44349168841 scopus 로고    scopus 로고
    • Mitochondria-dependent signalling pathway are involved in the early process of radiation-induced bystander effects
    • Chen S., Zhao Y., Han W., Zhao G., Zhu L., Wang J., Bao L., Jiang E., Xu A., Hei T. Mitochondria-dependent signalling pathway are involved in the early process of radiation-induced bystander effects. Br. J. Cancer 2008, 98:1839-1844.
    • (2008) Br. J. Cancer , vol.98 , pp. 1839-1844
    • Chen, S.1    Zhao, Y.2    Han, W.3    Zhao, G.4    Zhu, L.5    Wang, J.6    Bao, L.7    Jiang, E.8    Xu, A.9    Hei, T.10
  • 69
    • 65749108526 scopus 로고    scopus 로고
    • Up-regulation of ROS by mitochondria-dependent bystander signaling contributes to genotoxicity of bystander effects
    • Chen S., Zhao Y., Zhao G., Han W., Bao L., Yu K., Wu L. Up-regulation of ROS by mitochondria-dependent bystander signaling contributes to genotoxicity of bystander effects. Mutat. Res. 2009, 666:68-73.
    • (2009) Mutat. Res. , vol.666 , pp. 68-73
    • Chen, S.1    Zhao, Y.2    Zhao, G.3    Han, W.4    Bao, L.5    Yu, K.6    Wu, L.7
  • 70
    • 0037013331 scopus 로고    scopus 로고
    • Activation of constitutive nitric-oxide synthase activity is an early signaling event induced by ionizing radiation
    • Leach J.K., Black S.M., Schmidt-Ullrich R.K., Mikkelsen R.B. Activation of constitutive nitric-oxide synthase activity is an early signaling event induced by ionizing radiation. J. Biol. Chem. 2002, 277:15400-15406.
    • (2002) J. Biol. Chem. , vol.277 , pp. 15400-15406
    • Leach, J.K.1    Black, S.M.2    Schmidt-Ullrich, R.K.3    Mikkelsen, R.B.4
  • 71
    • 0035872421 scopus 로고    scopus 로고
    • Ionizing radiation-induced, mitochondria-dependent generation of reactive oxygen/nitrogen
    • Leach J.K., Van Tuyle G., Lin P.S., Schmidt-Ullrich R., Mikkelsen R.B. Ionizing radiation-induced, mitochondria-dependent generation of reactive oxygen/nitrogen. Cancer Res. 2001, 61:3894-3901.
    • (2001) Cancer Res. , vol.61 , pp. 3894-3901
    • Leach, J.K.1    Van Tuyle, G.2    Lin, P.S.3    Schmidt-Ullrich, R.4    Mikkelsen, R.B.5
  • 72
    • 34147190372 scopus 로고    scopus 로고
    • Constitutive nitric oxide acting as a possible intercellular signaling molecule in the initiation of radiation-induced DNA double strand breaks in non-irradiated bystander cells
    • Han W., Wu L., Chen S., Bao L., Zhang L., Jiang E., Zhao Y., Xu A., Hei T., Yu Z. Constitutive nitric oxide acting as a possible intercellular signaling molecule in the initiation of radiation-induced DNA double strand breaks in non-irradiated bystander cells. Oncogene 2006, 26:2330-2339.
    • (2006) Oncogene , vol.26 , pp. 2330-2339
    • Han, W.1    Wu, L.2    Chen, S.3    Bao, L.4    Zhang, L.5    Jiang, E.6    Zhao, Y.7    Xu, A.8    Hei, T.9    Yu, Z.10
  • 73
    • 77954995306 scopus 로고    scopus 로고
    • Regulation of early signaling and gene expression in the α-particle and bystander response of IMR-90 human fibroblasts
    • Ghandhi S.A., Ming L., Ivanov V.N., Hei T.K., Amundson S.A. Regulation of early signaling and gene expression in the α-particle and bystander response of IMR-90 human fibroblasts. BMC Med. Genomics 2010, 3:31.
    • (2010) BMC Med. Genomics , vol.3 , pp. 31
    • Ghandhi, S.A.1    Ming, L.2    Ivanov, V.N.3    Hei, T.K.4    Amundson, S.A.5
  • 74
    • 78650780108 scopus 로고    scopus 로고
    • Time-series clustering of gene expression in irradiated and bystander fibroblasts: an application of FBPA clustering
    • Ghandhi S., Sinha A., Markatou M., Amundson S. Time-series clustering of gene expression in irradiated and bystander fibroblasts: an application of FBPA clustering. BMC Genomics 2011, 12:2.
    • (2011) BMC Genomics , vol.12 , pp. 2
    • Ghandhi, S.1    Sinha, A.2    Markatou, M.3    Amundson, S.4
  • 75
    • 84875818957 scopus 로고    scopus 로고
    • Apoptosis is signalled early by low doses of ionizing radiation in a radiation-induced bystander effect
    • Furlong H., Mothersill C., Lyng F.M., Howe O. Apoptosis is signalled early by low doses of ionizing radiation in a radiation-induced bystander effect. Mutat. Res. 2013, 741-742:35-43.
    • (2013) Mutat. Res. , pp. 35-43
    • Furlong, H.1    Mothersill, C.2    Lyng, F.M.3    Howe, O.4
  • 76
    • 84255172290 scopus 로고    scopus 로고
    • Genome-wide microarray analysis of human fibroblasts in response to γ radiation and the radiation-induced bystander effect
    • Kalanxhi E., Dahle J. Genome-wide microarray analysis of human fibroblasts in response to γ radiation and the radiation-induced bystander effect. Radiat. Res. 2011, 177:35-43.
    • (2011) Radiat. Res. , vol.177 , pp. 35-43
    • Kalanxhi, E.1    Dahle, J.2
  • 77
    • 84867021555 scopus 로고    scopus 로고
    • Transcriptional responses in irradiated and bystander fibroblasts after low dose α-particle radiation
    • Kalanxhi E., Dahle J. Transcriptional responses in irradiated and bystander fibroblasts after low dose α-particle radiation. Int. J. Radiat. Biol. 2012, 88:713-719.
    • (2012) Int. J. Radiat. Biol. , vol.88 , pp. 713-719
    • Kalanxhi, E.1    Dahle, J.2
  • 78
    • 77955149415 scopus 로고    scopus 로고
    • Gene expression profile of human lymphocytes exposed to 211 at α particles
    • Turtoi A., Brown I., Schläger M., Schneeweiss F.H. Gene expression profile of human lymphocytes exposed to 211 at α particles. Radiat. Res. 2010, 174:125-136.
    • (2010) Radiat. Res. , vol.174 , pp. 125-136
    • Turtoi, A.1    Brown, I.2    Schläger, M.3    Schneeweiss, F.H.4
  • 79
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants, and aging
    • Balaban R.S., Nemoto S., Finkel T. Mitochondria, oxidants, and aging. Cell 2005, 120:483-495.
    • (2005) Cell , vol.120 , pp. 483-495
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 80
    • 0141673128 scopus 로고    scopus 로고
    • Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms
    • Mikkelsen R.B., Wardman P. Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms. Oncogene 2003, 22:5734-5754.
    • (2003) Oncogene , vol.22 , pp. 5734-5754
    • Mikkelsen, R.B.1    Wardman, P.2
  • 81
    • 67349262052 scopus 로고    scopus 로고
    • Mitochondrial dysfunction resulting from loss of cytochrome c impairs radiation-induced bystander effect
    • Yang G., Wu L., Chen S., Zhu L., Huang P., Tong L., Zhao Y., Zhao G., Wang J., Mei T. Mitochondrial dysfunction resulting from loss of cytochrome c impairs radiation-induced bystander effect. Br. J. Cancer 2009, 100:1912-1916.
    • (2009) Br. J. Cancer , vol.100 , pp. 1912-1916
    • Yang, G.1    Wu, L.2    Chen, S.3    Zhu, L.4    Huang, P.5    Tong, L.6    Zhao, Y.7    Zhao, G.8    Wang, J.9    Mei, T.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.