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Volumn 1, Issue 4, 2012, Pages 976-993

Redox mechanisms in regulation of adipocyte differentiation: Beyond a general stress response

Author keywords

Adipocyte; Adipogenesis; Differentiation; Obesity; Oxidative stress; Reactive oxygen species; Redox regulation

Indexed keywords

1, 4 DIAMINO 1, 4 BIS (2 AMINOPHENYLTHIO) 2, 3 DICYANOBUTADIENE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL) CHROMONE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ARGININE; CCAAT ENHANCER BINDING PROTEIN BETA; CYCLIC AMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLYCYRRHETINIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 17; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SOMATOMEDIN C; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

EID: 84912126826     PISSN: None     EISSN: 20734409     Source Type: Journal    
DOI: 10.3390/cells1040976     Document Type: Review
Times cited : (83)

References (119)
  • 3
  • 4
    • 0028587756 scopus 로고
    • Oxygen-derived species: Their relation to human disease and environmental stress
    • Halliwell, B.; Cross, C.E. Oxygen-derived species: Their relation to human disease and environmental stress. Environ. Health Perspect. 1994, 102 (Suppl. 10), 5-12.
    • (1994) Environ. Health Perspect. , vol.102 , Issue.SUPPL. 10 , pp. 5-12
    • Halliwell, B.1    Cross, C.E.2
  • 6
    • 79952026736 scopus 로고    scopus 로고
    • NADPH oxidase-mediated redox signaling: Roles in cellular stress response, stress tolerance, and tissue repair
    • Jiang, F.; Zhang, Y.; Dusting, G. NADPH oxidase-mediated redox signaling: roles in cellular stress response, stress tolerance, and tissue repair. Pharmacol. Rev. 2011, 63, 218-242.
    • (2011) Pharmacol. Rev. , vol.63 , pp. 218-242
    • Jiang, F.1    Zhang, Y.2    Dusting, G.3
  • 7
    • 64249117887 scopus 로고    scopus 로고
    • Regulation of cell proliferation by NADPH oxidase-mediated signaling: Potential roles in tissue repair, regenerative medicine and tissue engineering
    • Chan, E.C.; Jiang, F.; Peshavariya, H.M.; Dusting, G.J. Regulation of cell proliferation by NADPH oxidase-mediated signaling: Potential roles in tissue repair, regenerative medicine and tissue engineering. Pharmacol. Ther. 2009, 122, 97-108.
    • (2009) Pharmacol. Ther. , vol.122 , pp. 97-108
    • Chan, E.C.1    Jiang, F.2    Peshavariya, H.M.3    Dusting, G.J.4
  • 8
    • 79960286223 scopus 로고    scopus 로고
    • Signal transduction by reactive oxygen species
    • Finkel, T. Signal transduction by reactive oxygen species. J. Cell Biol. 2011, 194, 7-15.
    • (2011) J. Cell Biol. , vol.194 , pp. 7-15
    • Finkel, T.1
  • 9
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
    • Bedard, K.; Krause, K.H. The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology. Physiol. Rev. 2007, 87, 245-313.
    • (2007) Physiol. Rev. , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 10
    • 79551470306 scopus 로고    scopus 로고
    • SK Oxidative stress, insulin signaling, and diabetes
    • Rains, J.J. SK Oxidative stress, insulin signaling, and diabetes. Free Radic. Biol. Med. 2011, 50, 567-575.
    • (2011) Free Radic. Biol. Med. , vol.50 , pp. 567-575
    • Rains, J.J.1
  • 11
    • 0031882260 scopus 로고    scopus 로고
    • Reactive oxygen species as mediators of signal transduction in cardiovascular disease
    • Abe, J.; Berk, B. Reactive oxygen species as mediators of signal transduction in cardiovascular disease. Trends Cardiovasc. Med. 1998, 8, 59-64.
    • (1998) Trends Cardiovasc. Med. , vol.8 , pp. 59-64
    • Abe, J.1    Berk, B.2
  • 12
    • 18144383207 scopus 로고    scopus 로고
    • PTPs versus PTKs: The redox side of the coin
    • Chiarugi, P. PTPs versus PTKs: The redox side of the coin. Free Radic. Res. 2005, 39, 353-364.
    • (2005) Free Radic. Res. , vol.39 , pp. 353-364
    • Chiarugi, P.1
  • 13
    • 26244444476 scopus 로고    scopus 로고
    • Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases
    • Martyn, K.D.; Frederick, L.M.; Loehneysen, K.V.; Dinauer, M.C.; Knaus, U.G. Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases. Cell. Signal. 2006, 18, 69-82.
    • (2006) Cell. Signal. , vol.18 , pp. 69-82
    • Martyn, K.D.1    Frederick, L.M.2    Loehneysen, K.V.3    Dinauer, M.C.4    Knaus, U.G.5
  • 15
    • 79961011901 scopus 로고    scopus 로고
    • Reactive oxygen species mediate adipocyte differentiation in mesenchymal stem cells
    • Kanda, Y.; Hinata, T.; Kang, S.W.; Watanabe, Y. Reactive oxygen species mediate adipocyte differentiation in mesenchymal stem cells. Life Sci. 2011, 89, 250-258.
    • (2011) Life Sci. , vol.89 , pp. 250-258
    • Kanda, Y.1    Hinata, T.2    Kang, S.W.3    Watanabe, Y.4
  • 20
    • 58249093939 scopus 로고    scopus 로고
    • How mitochondria produce reactive oxygen species
    • Murphy, M. How mitochondria produce reactive oxygen species. Biochem. J. 2009, 417, 1-13.
    • (2009) Biochem. J. , vol.417 , pp. 1-13
    • Murphy, M.1
  • 23
    • 0038604446 scopus 로고    scopus 로고
    • Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: Implications for uncoupling endothelial nitricoxide synthase
    • Kuzkaya, N.; Weissmann, N.; Harrison, D.; Dikalov, S. Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: Implications for uncoupling endothelial nitricoxide synthase. J. Biol. Chem. 2003, 278, 22546-22554.
    • (2003) J. Biol. Chem. , vol.278 , pp. 22546-22554
    • Kuzkaya, N.1    Weissmann, N.2    Harrison, D.3    Dikalov, S.4
  • 24
    • 35348874911 scopus 로고    scopus 로고
    • Developmental origin of fat: Tracking obesity to its source
    • Gesta, S.; Tseng, Y.H.; Kahn, C.R. Developmental origin of fat: tracking obesity to its source. Cell 2007, 131, 242-256.
    • (2007) Cell , vol.131 , pp. 242-256
    • Gesta, S.1    Tseng, Y.H.2    Kahn, C.R.3
  • 25
    • 80054911514 scopus 로고    scopus 로고
    • Forming functional fat: A growing understanding of adipocyte differentiation
    • Cristancho, A.G.; Lazar, M.A. Forming functional fat: A growing understanding of adipocyte differentiation. Nat. Rev. Mol. Cell. Biol. 2011, 12, 722-734.
    • (2011) Nat. Rev. Mol. Cell. Biol. , vol.12 , pp. 722-734
    • Cristancho, A.G.1    Lazar, M.A.2
  • 26
    • 0033830783 scopus 로고    scopus 로고
    • Transcriptional control of adipogenesis
    • Rangwala, S.M.; Lazar, M.A. Transcriptional control of adipogenesis. Annu. Rev. Nutr. 2000, 20, 535-559.
    • (2000) Annu. Rev. Nutr. , vol.20 , pp. 535-559
    • Rangwala, S.M.1    Lazar, M.A.2
  • 27
    • 69149091047 scopus 로고    scopus 로고
    • BMP signaling pathway is required for commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage
    • Huang, H.; Song, T.J.; Li, X.; Hu, L.; He, Q.; Liu, M.; Lane, M.D.; Tang, Q.Q. BMP signaling pathway is required for commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage. Proc. Natl. Acad. Sci. USA 2009, 106, 12670-12675.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 12670-12675
    • Huang, H.1    Song, T.J.2    Li, X.3    Hu, L.4    He, Q.5    Liu, M.6    Lane, M.D.7    Tang, Q.Q.8
  • 28
    • 3042759742 scopus 로고    scopus 로고
    • Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage
    • Tang, Q.Q.; Otto, T.C.; Lane, M.D. Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage. Proc. Natl. Acad. Sci. USA 2004, 101, 9607-9611.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 9607-9611
    • Tang, Q.Q.1    Otto, T.C.2    Lane, M.D.3
  • 29
    • 38349184205 scopus 로고    scopus 로고
    • Osteoblasts directly control lineage commitment of mesenchymal progenitor cells through Wnt signaling
    • Zhou, H.; Mak, W.; Zheng, Y.; Dunstan, C.R.; Seibel, M.J. Osteoblasts directly control lineage commitment of mesenchymal progenitor cells through Wnt signaling. J. Biol. Chem. 2008, 283, 1936-1945.
    • (2008) J. Biol. Chem. , vol.283 , pp. 1936-1945
    • Zhou, H.1    Mak, W.2    Zheng, Y.3    Dunstan, C.R.4    Seibel, M.J.5
  • 31
    • 0030831977 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor γ, CCAAT/enhancer-binding protein α, and cell cycle status regulate the commitment to adipocyte differentiation
    • Shao, D.; Lazar, M.A. Peroxisome proliferator activated receptor γ, CCAAT/enhancer-binding protein α, and cell cycle status regulate the commitment to adipocyte differentiation. J. Biol. Chem. 1997, 272, 21473-21478.
    • (1997) J. Biol. Chem. , vol.272 , pp. 21473-21478
    • Shao, D.1    Lazar, M.A.2
  • 32
    • 0037417875 scopus 로고    scopus 로고
    • CCAAT/enhancer--binding protein β is required for mitotic clonal expansion during adipogenesis
    • Tang, Q.Q.; Otto, T.C.; Lane, M.D. CCAAT/enhancer--binding protein β is required for mitotic clonal expansion during adipogenesis. Proc. Natl. Acad. Sci. USA 2003, 100, 850-855.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 850-855
    • Tang, Q.Q.1    Otto, T.C.2    Lane, M.D.3
  • 33
    • 84856435413 scopus 로고    scopus 로고
    • Transcriptional networks and chromatin remodeling controlling adipogenesis
    • Siersbæk, R.; Nielsen, R.; Mandrup, S. Transcriptional networks and chromatin remodeling controlling adipogenesis. Trends Endocrinol. Metab. 2012, 23, 56-64.
    • (2012) Trends Endocrinol. Metab. , vol.23 , pp. 56-64
    • Siersbæk, R.1    Nielsen, R.2    Mandrup, S.3
  • 34
    • 41449116010 scopus 로고    scopus 로고
    • Transcriptional regulation of adipogenesis by KLF4
    • Birsoy, K.; Chen, Z.; Friedman, J. Transcriptional regulation of adipogenesis by KLF4. Cell. Metab. 2008, 7, 339-347.
    • (2008) Cell. Metab. , vol.7 , pp. 339-347
    • Birsoy, K.1    Chen, Z.2    Friedman, J.3
  • 35
    • 1042289760 scopus 로고    scopus 로고
    • Role of CREB in transcriptional regulation of CCAAT/enhancer-binding protein β gene during adipogenesis
    • Zhang, J.W.; Klemm, D.J.; Vinson, C.; Lane, M.D. Role of CREB in transcriptional regulation of CCAAT/enhancer-binding protein β gene during adipogenesis. J. Biol. Chem. 2004, 279, 4471-4478.
    • (2004) J. Biol. Chem. , vol.279 , pp. 4471-4478
    • Zhang, J.W.1    Klemm, D.J.2    Vinson, C.3    Lane, M.D.4
  • 36
    • 24344507734 scopus 로고    scopus 로고
    • Krox20 stimulates adipogenesis via C/EBP[beta]-dependent and-independent mechanisms
    • Chen, Z.; Torrens, J.I.; Anand, A.; Spiegelman, B.M.; Friedman, J.M. Krox20 stimulates adipogenesis via C/EBP[beta]-dependent and-independent mechanisms. Cell. Metab. 2005, 1, 93-106.
    • (2005) Cell. Metab. , vol.1 , pp. 93-106
    • Chen, Z.1    Torrens, J.I.2    Anand, A.3    Spiegelman, B.M.4    Friedman, J.M.5
  • 37
    • 79251643937 scopus 로고    scopus 로고
    • JAK2/STAT3 pathway is involved in the early stage of adipogenesis through regulating C/EBPβ transcription
    • Zhang, K.; Guo, W.; Yang, Y.; Wu, J. JAK2/STAT3 pathway is involved in the early stage of adipogenesis through regulating C/EBPβ transcription. J. Biol. Chem. 2011, 112, 488-497.
    • (2011) J. Biol. Chem. , vol.112 , pp. 488-497
    • Zhang, K.1    Guo, W.2    Yang, Y.3    Wu, J.4
  • 38
    • 22244479353 scopus 로고    scopus 로고
    • Sequential phosphorylation of CCAAT enhancer-binding protein β by MAPK and glycogen synthase kinase 3β is required tor adi{dotless}nogenesi{dotless}s
    • Tang, Q.Q.; Grønborg, M.; Huang, H.; Kim, J.W.; Otto, T.C.; Pandey, A.; Lane, M.D. Sequential phosphorylation of CCAAT enhancer-binding protein β by MAPK and glycogen synthase kinase 3β is required tor adi{dotless}nogenesi{dotless}s. Proc. Natl. Acad. Sci. USA 2005, 102, 9766-9771.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 9766-9771
    • Tang, Q.Q.1    Grønborg, M.2    Huang, H.3    Kim, J.W.4    Otto, T.C.5    Pandey, A.6    Lane, M.D.7
  • 39
    • 0028878375 scopus 로고
    • Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins
    • Yeh, W.C.; Cao, Z.; Classon, M.; McKnight, S.L. Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins. Genes Dev. 1995, 9, 168-181.
    • (1995) Genes Dev. , vol.9 , pp. 168-181
    • Yeh, W.C.1    Cao, Z.2    Classon, M.3    McKnight, S.L.4
  • 40
    • 33847284069 scopus 로고    scopus 로고
    • Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPβ by GCN5
    • Wiper-Bergeron, N.; Salem, H.A.; Tomlinson, J.J.; Wu, D.; Haché, R.J.G. Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPβ by GCN5. Proc. Natl. Acad. Sci. USA 2007, 104, 2703-2708.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 2703-2708
    • Wiper-Bergeron, N.1    Salem, H.A.2    Tomlinson, J.J.3    Wu, D.4    Haché, R.J.G.5
  • 41
    • 33748942837 scopus 로고    scopus 로고
    • Transcriptional control of adipocyte formation
    • Farmer, S.R. Transcriptional control of adipocyte formation. Cell. Metab. 2006, 4, 263-273.
    • (2006) Cell. Metab. , vol.4 , pp. 263-273
    • Farmer, S.R.1
  • 42
    • 0037312827 scopus 로고    scopus 로고
    • STAT5A promotes adipogenesis in nonprecursor cells and associates with the glucocorticoid receptor during adipocyte differentiation
    • Floyd, Z.E.; Stephens, J.M. STAT5A promotes adipogenesis in nonprecursor cells and associates with the glucocorticoid receptor during adipocyte differentiation. Diabetes 2003, 52, 308-314.
    • (2003) Diabetes , vol.52 , pp. 308-314
    • Floyd, Z.E.1    Stephens, J.M.2
  • 44
    • 55749101777 scopus 로고    scopus 로고
    • Genome-wide profiling of PPARy: RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis
    • Nielsen, R.; Pedersen, T. Â.; Hagenbeek, D.; Moulos, P.; Siersb^k, R.; Megens, E.; Denissov, S.; Borgesen, M.; Francoijs, K.J.; Mandrup, S. Genome-wide profiling of PPARy: RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis. Genes Dev. 2008, 22, 2953-2967.
    • (2008) Genes Dev. , vol.22 , pp. 2953-2967
    • Nielsen, R.1    Pedersen, T.A.2    Hagenbeek, D.3    Moulos, P.4    Siersbk, R.5    Megens, E.6    Denissov, S.7    Borgesen, M.8    Francoijs, K.J.9    Mandrup, S.10
  • 45
    • 50649097541 scopus 로고    scopus 로고
    • Fat and beyond: The diverse biology of PPARy
    • Tontonoz, P.; Spiegelman, B.M. Fat and beyond: the diverse biology of PPARy. Annu. Rev. Biochem. 2008, 77, 289-312.
    • (2008) Annu. Rev. Biochem. , vol.77 , pp. 289-312
    • Tontonoz, P.1    Spiegelman, B.M.2
  • 47
    • 0030007427 scopus 로고    scopus 로고
    • ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism
    • Kim, J.B.; Spiegelman, B.M. ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. Genes Dev. 1996, 10, 1096-1107.
    • (1996) Genes Dev. , vol.10 , pp. 1096-1107
    • Kim, J.B.1    Spiegelman, B.M.2
  • 48
    • 84861043736 scopus 로고    scopus 로고
    • Connecting mTORC1 signaling to SREBP-1 activation
    • Bakan, I.; Laplante, M. Connecting mTORC1 signaling to SREBP-1 activation. Curr. Opin. Lipidol. 2012, 23, 226-234.
    • (2012) Curr. Opin. Lipidol. , vol.23 , pp. 226-234
    • Bakan, I.1    Laplante, M.2
  • 49
  • 50
    • 0033572654 scopus 로고    scopus 로고
    • Functional antagonism between inhibitor of DNA binding (Id) and adipocyte determination and differentiation factor 1/sterol regulatory element-binding protein-1c (ADD1/SREBP-1c) trans-factors for the regulation of fatty acid synthase promoter in adipocytes
    • Moldes, M.; Boizard, M.; Liepvre, X.; Feve, B.; Dugail, I.; Pairault, J. Functional antagonism between inhibitor of DNA binding (Id) and adipocyte determination and differentiation factor 1/sterol regulatory element-binding protein-1c (ADD1/SREBP-1c) trans-factors for the regulation of fatty acid synthase promoter in adipocytes. Biochem. J. 1999, 344, 873-880.
    • (1999) Biochem. J. , vol.344 , pp. 873-880
    • Moldes, M.1    Boizard, M.2    Liepvre, X.3    Feve, B.4    Dugail, I.5    Pairault, J.6
  • 52
    • 64049089450 scopus 로고    scopus 로고
    • SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXOl's repressive interaction with PPARy
    • Wang, F.; Tong, Q. SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXOl's repressive interaction with PPARy. Mol. Biol. Cell. 2009, 20, 801-808.
    • (2009) Mol. Biol. Cell. , vol.20 , pp. 801-808
    • Wang, F.1    Tong, Q.2
  • 58
    • 34547397081 scopus 로고    scopus 로고
    • SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation
    • Jing, E.; Gesta, S.; Kahn, C.R. SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation. Cell. Metab. 2007, 6, 105-114.
    • (2007) Cell. Metab. , vol.6 , pp. 105-114
    • Jing, E.1    Gesta, S.2    Kahn, C.R.3
  • 59
    • 79953186142 scopus 로고    scopus 로고
    • PGC-1 coactivators in the control of energy metabolism
    • Liu, C.; Lin, J.D. PGC-1 coactivators in the control of energy metabolism. Acta Biochim. Biophys. Sin. (Shanghai) 2011, 43, 248-257.
    • (2011) Acta Biochim. Biophys. Sin. (Shanghai) , vol.43 , pp. 248-257
    • Liu, C.1    Lin, J.D.2
  • 60
    • 79953210362 scopus 로고    scopus 로고
    • Regulation of PGC-1alpha, a nodal regulator of mitochondrial biogenesis
    • Fernandez-Marcos, P.J.; Auwerx, J. Regulation of PGC-1alpha, a nodal regulator of mitochondrial biogenesis. Am. J. Clin. Nutr. 2011, 93, S884-S890.
    • (2011) Am. J. Clin. Nutr. , vol.93
    • Fernandez-Marcos, P.J.1    Auwerx, J.2
  • 61
    • 67651208171 scopus 로고    scopus 로고
    • PGC-1alpha-induced improvements in skeletal muscle metabolism and insulin sensitivity
    • Bonen, A. PGC-1alpha-induced improvements in skeletal muscle metabolism and insulin sensitivity. Appl. Physiol. Nutr. Metab. 2009, 34, 307-314.
    • (2009) Appl. Physiol. Nutr. Metab. , vol.34 , pp. 307-314
    • Bonen, A.1
  • 63
    • 0033710665 scopus 로고    scopus 로고
    • Regulation of adipogenesis and energy balance by PPARgamma and PGC-1
    • Spiegelman, B.M.; Puigserver, P.; Wu, Z. Regulation of adipogenesis and energy balance by PPARgamma and PGC-1. Int. J. Obes. Relat. Metab. Disord. 2000, 24 (Suppl. 4), S8-S10.
    • (2000) Int. J. Obes. Relat. Metab. Disord. , vol.24 , Issue.SUPPL. 4
    • Spiegelman, B.M.1    Puigserver, P.2    Wu, Z.3
  • 65
    • 33644673002 scopus 로고    scopus 로고
    • Impaired generation of reactive oxygen species in leprechaunism through downregulation of Nox4
    • Park, H.S.; Jin, D.K.; Shin, S.M.; Jang, M.K.; Longo, N.; Park, J.W.; Bae, D.S.; Bae, Y.S. Impaired generation of reactive oxygen species in leprechaunism through downregulation of Nox4. Diabetes 2005, 54, 3175-3181.
    • (2005) Diabetes , vol.54 , pp. 3175-3181
    • Park, H.S.1    Jin, D.K.2    Shin, S.M.3    Jang, M.K.4    Longo, N.5    Park, J.W.6    Bae, D.S.7    Bae, Y.S.8
  • 67
    • 1342304048 scopus 로고    scopus 로고
    • The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and plays an integral role in insulin signal transduction
    • Mahadev, K.; Motoshima, H.; Wu, X.; Ruddy, J.M.; Arnold, R.S.; Cheng, G.; Lambeth, J.D.; Goldstein, B.J. The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and plays an integral role in insulin signal transduction. Mol. Cell. Biol. 2004, 24, 1844-1854.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 1844-1854
    • Mahadev, K.1    Motoshima, H.2    Wu, X.3    Ruddy, J.M.4    Arnold, R.S.5    Cheng, G.6    Lambeth, J.D.7    Goldstein, B.J.8
  • 69
    • 0142038998 scopus 로고    scopus 로고
    • Inhibition of preadipocyte proliferation by mitochondrial reactive oxygen species
    • Carriere, A.; Fernandez, Y.; Rigoulet, M.; Penicaud, L.; Casteilla, L. Inhibition of preadipocyte proliferation by mitochondrial reactive oxygen species. FEBS Lett. 2003, 550, 163-167.
    • (2003) FEBS Lett. , vol.550 , pp. 163-167
    • Carriere, A.1    Fernandez, Y.2    Rigoulet, M.3    Penicaud, L.4    Casteilla, L.5
  • 75
    • 0034997937 scopus 로고    scopus 로고
    • Increases in nitric oxide concentrations correlate strongly with body fat in obese humans
    • Choi, J.W.; Pai, S.H.; Kim, S.K.; Ito, M.; Park, C.S.; Cha, Y.N. Increases in nitric oxide concentrations correlate strongly with body fat in obese humans. Clin. Chem. 2001, 47, 1106-1109.
    • (2001) Clin. Chem. , vol.47 , pp. 1106-1109
    • Choi, J.W.1    Pai, S.H.2    Kim, S.K.3    Ito, M.4    Park, C.S.5    Cha, Y.N.6
  • 78
    • 84862726271 scopus 로고    scopus 로고
    • MCP-1 induced protein promotes adipogenesis via oxidative stress, endoplasmic reticulum stress and autophagy
    • Younce, C.; Kolattukudy, P. MCP-1 induced protein promotes adipogenesis via oxidative stress, endoplasmic reticulum stress and autophagy. Cell Physiol. Biochem. 2012, 30, 307-320.
    • (2012) Cell Physiol. Biochem. , vol.30 , pp. 307-320
    • Younce, C.1    Kolattukudy, P.2
  • 79
    • 84861093485 scopus 로고    scopus 로고
    • Fullerol antagonizes dexamethasoneinduced oxidative stress and adipogenesis while enhancing osteogenesis in a cloned bone marrow mesenchymal stem cell
    • Liu, H.; Yang, X.; Zhang, Y.; Dighe, A.; Li, X.; Cui, Q. Fullerol antagonizes dexamethasoneinduced oxidative stress and adipogenesis while enhancing osteogenesis in a cloned bone marrow mesenchymal stem cell. J. Orthop. Res. 2012, 30, 1051-1057.
    • (2012) J. Orthop. Res. , vol.30 , pp. 1051-1057
    • Liu, H.1    Yang, X.2    Zhang, Y.3    Dighe, A.4    Li, X.5    Cui, Q.6
  • 80
    • 84861120128 scopus 로고    scopus 로고
    • RNA interference targeting cytosolic NADP(+)-dependent isocitrate dehydrogenase exerts anti-obesity effect in vitro and in vivo
    • Nam, W.S.; Park, K.M.; Park, J.W. RNA interference targeting cytosolic NADP(+)-dependent isocitrate dehydrogenase exerts anti-obesity effect in vitro and in vivo. Biochim. Biophys. Acta 2012, 1822, 1181-1188.
    • (2012) Biochim. Biophys. Acta , vol.1822 , pp. 1181-1188
    • Nam, W.S.1    Park, K.M.2    Park, J.W.3
  • 81
    • 84855453637 scopus 로고    scopus 로고
    • Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein beta during adipogenesis
    • Hou, Y.; Xue, P.; Bai, Y.; Liu, D.; Woods, C.G.; Yarborough, K.; Fu, J.; Zhang, Q.; Sun, G.; Collins, S.; et al. Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein beta during adipogenesis. Free Radic. Biol. Med. 2012, 52, 462-472.
    • (2012) Free Radic. Biol. Med. , vol.52 , pp. 462-472
    • Hou, Y.1    Xue, P.2    Bai, Y.3    Liu, D.4    Woods, C.G.5    Yarborough, K.6    Fu, J.7    Zhang, Q.8    Sun, G.9    Collins, S.10
  • 82
    • 79955535556 scopus 로고    scopus 로고
    • Differential redox potential profiles during adipogenesis and osteogenesis
    • Imhoff, B.R.; Hansen, J.M. Differential redox potential profiles during adipogenesis and osteogenesis. Cell. Mol. Biol. Lett. 2011, 16, 149-161.
    • (2011) Cell. Mol. Biol. Lett. , vol.16 , pp. 149-161
    • Imhoff, B.R.1    Hansen, J.M.2
  • 83
    • 77956366445 scopus 로고    scopus 로고
    • Novel polyhydroxylated fullerene suppresses intracellular oxidative stress together with repression of intracellular lipid accumulation during the differentiation of OP9 preadipocytes into adipocytes
    • Saitoh, Y.; Xiao, L.; Mizuno, H.; Kato, S.; Aoshima, H.; Taira, H.; Kokubo, K.; Miwa, N. Novel polyhydroxylated fullerene suppresses intracellular oxidative stress together with repression of intracellular lipid accumulation during the differentiation of OP9 preadipocytes into adipocytes. Free Radic. Res. 2010, 44, 1072-1081.
    • (2010) Free Radic. Res. , vol.44 , pp. 1072-1081
    • Saitoh, Y.1    Xiao, L.2    Mizuno, H.3    Kato, S.4    Aoshima, H.5    Taira, H.6    Kokubo, K.7    Miwa, N.8
  • 85
    • 79955104610 scopus 로고    scopus 로고
    • Modulation of intracellular glutathione affects adipogenesis in 3T3-L1 cells
    • Vigilanza, P.; Aquilano, K.; Baldelli, S.; Rotilio, G.; Ciriolo, M.R. Modulation of intracellular glutathione affects adipogenesis in 3T3-L1 cells. J. Cell Physiol. 2011, 226, 2016-2024.
    • (2011) J. Cell Physiol. , vol.226 , pp. 2016-2024
    • Vigilanza, P.1    Aquilano, K.2    Baldelli, S.3    Rotilio, G.4    Ciriolo, M.R.5
  • 87
    • 77954142412 scopus 로고    scopus 로고
    • Extracellular redox environments regulate adipocyte differentiation
    • Imhoff, B.R.; Hansen, J.M. Extracellular redox environments regulate adipocyte differentiation. Differentiation 2010, 80, 31-39.
    • (2010) Differentiation , vol.80 , pp. 31-39
    • Imhoff, B.R.1    Hansen, J.M.2
  • 88
    • 85117873840 scopus 로고    scopus 로고
    • Differentiation of human adipose-derived stem cells into fat involves reactive oxygen species and Forkhead Box O1 mediated upregulation of antioxidant enzymes
    • in press
    • Higuchi, M.; Dusting, G.J.; Peshavariya, H.; Jiang, F.; Hsiao, S.T.-F.; Chan, E.C.; Liu, G.-S. Differentiation of human adipose-derived stem cells into fat involves reactive oxygen species and Forkhead Box O1 mediated upregulation of antioxidant enzymes. Stem. Cells Dev. 2012, in press.
    • (2012) Stem. Cells Dev.
    • Higuchi, M.1    Dusting, G.J.2    Peshavariya, H.3    Jiang, F.4    Hsiao, S.T.-F.5    Chan, E.C.6    Liu, G.-S.7
  • 90
    • 78651452954 scopus 로고    scopus 로고
    • IL-17A promotes transdifferentiation of mouse myoblast cells (C2C12) into adipocytes by increasing the expression of peroxisome proliferator-activated receptor gamma through CAAT/enhancer binding protein beta signaling
    • Lee, S.J.; Lee, E.J.; Kim, S.H.; Choi, I.; Lee, D.M.; Lee, H.J.; Yoon, D.; Chun, T. IL-17A promotes transdifferentiation of mouse myoblast cells (C2C12) into adipocytes by increasing the expression of peroxisome proliferator-activated receptor gamma through CAAT/enhancer binding protein beta signaling. Biotechnol. Lett. 2011, 33, 229-235.
    • (2011) Biotechnol. Lett. , vol.33 , pp. 229-235
    • Lee, S.J.1    Lee, E.J.2    Kim, S.H.3    Choi, I.4    Lee, D.M.5    Lee, H.J.6    Yoon, D.7    Chun, T.8
  • 92
    • 35848941517 scopus 로고    scopus 로고
    • 18alpha-glycyrrhetinic acid induces phenotypic changes of skeletal muscle cells to enter adipogenesis
    • Yamanouchi, K.; Yada, E.; Ishiguro, N.; Nishihara, M. 18alpha-glycyrrhetinic acid induces phenotypic changes of skeletal muscle cells to enter adipogenesis. Cell. Physiol. Biochem. 2007, 20, 781-790.
    • (2007) Cell. Physiol. Biochem. , vol.20 , pp. 781-790
    • Yamanouchi, K.1    Yada, E.2    Ishiguro, N.3    Nishihara, M.4
  • 93
    • 77953025879 scopus 로고    scopus 로고
    • Transdifferentiation of fibroblasts into adipocyte-like cells by chicken adipogenic transcription factors
    • Liu, S.; Wang, Y.; Wang, L.; Wang, N.; Li, Y.; Li, H. Transdifferentiation of fibroblasts into adipocyte-like cells by chicken adipogenic transcription factors. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 2010, 156, 502-508.
    • (2010) Comp. Biochem. Physiol. A Mol. Integr. Physiol. , vol.156 , pp. 502-508
    • Liu, S.1    Wang, Y.2    Wang, L.3    Wang, N.4    Li, Y.5    Li, H.6
  • 94
    • 0023919926 scopus 로고
    • Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes
    • Smith, P.J.; Wise, L.S.; Berkowitz, R.; Wan, C.; Rubin, C.S. Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes. J. Biol. Chem. 1988, 263, 9402-9408.
    • (1988) J. Biol. Chem. , vol.263 , pp. 9402-9408
    • Smith, P.J.1    Wise, L.S.2    Berkowitz, R.3    Wan, C.4    Rubin, C.S.5
  • 95
    • 0037195843 scopus 로고    scopus 로고
    • Activation of MEK/ERK signaling promotes adipogenesis by enhancing peroxisome proliferator-activated receptor gamma (PPARgamma) and C/EBPalpha gene expression during the differentiation of 3T3-L1 preadipocytes
    • Prusty, D.; Park, B.H.; Davis, K.E.; Farmer, S.R. Activation of MEK/ERK signaling promotes adipogenesis by enhancing peroxisome proliferator-activated receptor gamma (PPARgamma) and C/EBPalpha gene expression during the differentiation of 3T3-L1 preadipocytes. J. Biol. Chem. 2002, 277, 46226-46232.
    • (2002) J. Biol. Chem. , vol.277 , pp. 46226-46232
    • Prusty, D.1    Park, B.H.2    Davis, K.E.3    Farmer, S.R.4
  • 96
    • 0017853459 scopus 로고
    • Activation of glycogen synthase in rat adipocytes by insulin and glucose involves increased glucose transport and phosphorylation
    • Lawrence, J.C., Jr.; Larner, J. Activation of glycogen synthase in rat adipocytes by insulin and glucose involves increased glucose transport and phosphorylation. J. Biol. Chem. 1978, 253, 2104-2113.
    • (1978) J. Biol. Chem. , vol.253 , pp. 2104-2113
    • Lawrence Jr., J.C.1    Larner, J.2
  • 97
    • 0018382583 scopus 로고
    • Insulin-stimulated intracellular hydrogen peroxide production in rat epididymal fat cells
    • May, J.M.; de Haen, C. Insulin-stimulated intracellular hydrogen peroxide production in rat epididymal fat cells. J. Biol. Chem. 1979, 254, 2214-2220.
    • (1979) J. Biol. Chem. , vol.254 , pp. 2214-2220
    • May, J.M.1    de Haen, C.2
  • 98
    • 4444233558 scopus 로고    scopus 로고
    • Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B
    • Meng, T.C.; Buckley, D.A.; Galic, S.; Tiganis, T.; Tonks, N.K. Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B. J. Biol. Chem. 2004, 279, 37716-37725.
    • (2004) J. Biol. Chem. , vol.279 , pp. 37716-37725
    • Meng, T.C.1    Buckley, D.A.2    Galic, S.3    Tiganis, T.4    Tonks, N.K.5
  • 99
    • 12744279326 scopus 로고    scopus 로고
    • Redox paradox: Insulin action is facilitated by insulinstimulated reactive oxygen species with multiple potential signaling targets
    • Goldstein, B.J.; Mahadev, K.; Wu, X. Redox paradox: insulin action is facilitated by insulinstimulated reactive oxygen species with multiple potential signaling targets. Diabetes 2005, 54, 311-321.
    • (2005) Diabetes , vol.54 , pp. 311-321
    • Goldstein, B.J.1    Mahadev, K.2    Wu, X.3
  • 100
    • 4544250814 scopus 로고    scopus 로고
    • Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells
    • Vaquero, E.C.; Edderkaoui, M.; Pandol, S.J.; Gukovsky, I.; Gukovskaya, A.S. Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells. J. Biol. Chem. 2004, 279, 34643-34654.
    • (2004) J. Biol. Chem. , vol.279 , pp. 34643-34654
    • Vaquero, E.C.1    Edderkaoui, M.2    Pandol, S.J.3    Gukovsky, I.4    Gukovskaya, A.S.5
  • 102
    • 79959372910 scopus 로고    scopus 로고
    • The pivotal role of reactive oxygen species generation in the hypoxia-induced stimulation of adipose-derived stem cells
    • Kim, J.H.; Park, S.H.; Park, S.G.; Choi, J.S.; Xia, Y.; Sung, J.H. The pivotal role of reactive oxygen species generation in the hypoxia-induced stimulation of adipose-derived stem cells. Stem. Cells. Dev. 2011, 20, 1753-1761.
    • (2011) Stem. Cells. Dev. , vol.20 , pp. 1753-1761
    • Kim, J.H.1    Park, S.H.2    Park, S.G.3    Choi, J.S.4    Xia, Y.5    Sung, J.H.6
  • 103
    • 84855681355 scopus 로고    scopus 로고
    • Adipose tissue stem cells meet preadipocyte commitment: Going back to the future
    • Cawthorn, W.P.; Scheller, E.L.; MacDougald, O.A. Adipose tissue stem cells meet preadipocyte commitment: Going back to the future. J. Lipid. Res. 2012, 53, 227-246.
    • (2012) J. Lipid. Res. , vol.53 , pp. 227-246
    • Cawthorn, W.P.1    Scheller, E.L.2    MacDougald, O.A.3
  • 104
    • 14544298335 scopus 로고    scopus 로고
    • The role of MAPKs in adipocyte differentiation and obesity
    • Bost, F.; Aouadi, M.; Caron, L.; Binetruy, B. The role of MAPKs in adipocyte differentiation and obesity. Biochimie 2005, 87, 51-56.
    • (2005) Biochimie , vol.87 , pp. 51-56
    • Bost, F.1    Aouadi, M.2    Caron, L.3    Binetruy, B.4
  • 105
    • 33644772497 scopus 로고    scopus 로고
    • Involvement of PPARgamma in oxidative stress-mediated prostaglandin E(2) production in SZ95 human sebaceous gland cells
    • Zhang, Q.; Seltmann, H.; Zouboulis, C.C.; Konger, R.L. Involvement of PPARgamma in oxidative stress-mediated prostaglandin E(2) production in SZ95 human sebaceous gland cells. J. Invest. Dermatol. 2006, 126, 42-48.
    • (2006) J. Invest. Dermatol. , vol.126 , pp. 42-48
    • Zhang, Q.1    Seltmann, H.2    Zouboulis, C.C.3    Konger, R.L.4
  • 106
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
    • Nagy, L.; Tontonoz, P.; Alvarez, J.G.; Chen, H.; Evans, R.M. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell 1998, 93, 229-240.
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3    Chen, H.4    Evans, R.M.5
  • 107
    • 77951242122 scopus 로고    scopus 로고
    • Covalent peroxisome proliferatoractivated receptor gamma adduction by nitro-fatty acids: Selective ligand activity and anti-diabetic signaling actions
    • Schopfer, F.J.; Cole, M.P.; Groeger, A.L.; Chen, C.S.; Khoo, N.K.; Woodcock, S.R.; Golin-Bisello, F.; Motanya, U.N.; Li, Y.; Zhang, J.; et al. Covalent peroxisome proliferatoractivated receptor gamma adduction by nitro-fatty acids: Selective ligand activity and anti-diabetic signaling actions. J. Biol. Chem. 2010, 285, 12321-12333.
    • (2010) J. Biol. Chem. , vol.285 , pp. 12321-12333
    • Schopfer, F.J.1    Cole, M.P.2    Groeger, A.L.3    Chen, C.S.4    Khoo, N.K.5    Woodcock, S.R.6    Golin-Bisello, F.7    Motanya, U.N.8    Li, Y.9    Zhang, J.10
  • 108
  • 109
    • 34547545892 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
    • Jager, S.; Handschin, C.; St-Pierre, J.; Spiegelman, B.M. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc. Natl. Acad. Sci. USA 2007, 104, 12017-12022.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 12017-12022
    • Jager, S.1    Handschin, C.2    St-Pierre, J.3    Spiegelman, B.M.4
  • 110
    • 84862849835 scopus 로고    scopus 로고
    • Redox implications of AMPK-mediated signal transduction beyond energetic clues
    • Cardaci, S.; Filomeni, G.; Ciriolo, M.R. Redox implications of AMPK-mediated signal transduction beyond energetic clues. J. Cell Sci. 2012, 125, 2115-2125.
    • (2012) J. Cell Sci. , vol.125 , pp. 2115-2125
    • Cardaci, S.1    Filomeni, G.2    Ciriolo, M.R.3
  • 111
    • 70350020773 scopus 로고    scopus 로고
    • Exercise activation of muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling is redox sensitive
    • Kang, C.; O'Moore, K.M.; Dickman, J.R.; Ji, L.L. Exercise activation of muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling is redox sensitive. Free Radic. Biol. Med. 2009, 47, 1394-1400.
    • (2009) Free Radic. Biol. Med. , vol.47 , pp. 1394-1400
    • Kang, C.1    O'Moore, K.M.2    Dickman, J.R.3    Ji, L.L.4
  • 112
    • 33846909947 scopus 로고    scopus 로고
    • Effect of phosphorylation and S-S bond-induced dimerization on DNA binding and transcriptional activation by C/EBPbeta
    • Kim, J.W.; Tang, Q.Q.; Li, X.; Lane, M.D. Effect of phosphorylation and S-S bond-induced dimerization on DNA binding and transcriptional activation by C/EBPbeta. Proc. Natl. Acad. Sci. USA 2007, 104, 1800-1804.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 1800-1804
    • Kim, J.W.1    Tang, Q.Q.2    Li, X.3    Lane, M.D.4
  • 113
    • 67449091887 scopus 로고    scopus 로고
    • Reactive oxygen species facilitate adipocyte differentiation by accelerating mitotic clonal expansion
    • Lee, H.; Lee, Y.J.; Choi, H.; Ko, E.H.; Kim, J.W. Reactive oxygen species facilitate adipocyte differentiation by accelerating mitotic clonal expansion. J. Biol. Chem. 2009, 284, 10601-10609.
    • (2009) J. Biol. Chem. , vol.284 , pp. 10601-10609
    • Lee, H.1    Lee, Y.J.2    Choi, H.3    Ko, E.H.4    Kim, J.W.5
  • 114
    • 67349273307 scopus 로고    scopus 로고
    • Metabolic syndrome and oxidative stress
    • Ando, K.; Fujita, T. Metabolic syndrome and oxidative stress. Free Radic. Biol. Med. 2009, 47, 213-218.
    • (2009) Free Radic. Biol. Med. , vol.47 , pp. 213-218
    • Ando, K.1    Fujita, T.2
  • 116
    • 84866133072 scopus 로고    scopus 로고
    • Reactive oxygen species in health and disease
    • Alfadda, A.A.; Sallam, R.M. Reactive oxygen species in health and disease. J. Biomed. Biotechnol. 2012, 2012, 936486.
    • (2012) J. Biomed. Biotechnol. , vol.2012 , pp. 936486
    • Alfadda, A.A.1    Sallam, R.M.2
  • 117
    • 33750562169 scopus 로고    scopus 로고
    • Systemic oxidative stress is associated with visceral fat accumulation and the metabolic syndrome
    • Fujita, K.; Nishizawa, H.; Funahashi, T.; Shimomura, I.; Shimabukuro, M. Systemic oxidative stress is associated with visceral fat accumulation and the metabolic syndrome. Circ. J. 2006, 70, 1437-1442.
    • (2006) Circ. J. , vol.70 , pp. 1437-1442
    • Fujita, K.1    Nishizawa, H.2    Funahashi, T.3    Shimomura, I.4    Shimabukuro, M.5
  • 118
    • 33644633736 scopus 로고    scopus 로고
    • Biomarkers and potential mechanisms of obesity-induced oxidant stress in humans
    • Vincent, H.K.; Taylor, A.G. Biomarkers and potential mechanisms of obesity-induced oxidant stress in humans. Int. J. Obes. (Lond) 2006, 30, 400-418.
    • (2006) Int. J. Obes. (Lond) , vol.30 , pp. 400-418
    • Vincent, H.K.1    Taylor, A.G.2


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