A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14

EMBO Journal

Volumn 20, Issue 18, 2001, Pages 5187-5196

  Borodovsky, Anna ^a   Kessler, Benedikt M ^a   Casagrande, Rocco ^a   Overkleeft, Herman S ^a   Wilkinson, Keith D ^b   Ploegh, Hidde L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Active site directed prob; Deubiquitylating enzyme; Proteasome; Ubiquitin; Vinyl sulfone

Indexed keywords

ALDEHYDE; FUNGAL ENZYME; HYDROLASE; N ETHYLMALEIMIDE; POLYPEPTIDE; PROTEASOME; PROTEINASE; SULFONE; UBIQUITIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHEMICAL LABELING; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME INHIBITION; ENZYME MODIFICATION; ENZYME SPECIFICITY; FUNGUS MUTANT; GENETIC ANALYSIS; ISOTOPE LABELING; MAMMAL CELL; MOLECULAR PROBE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

3T3 CELLS; ANIMALS; BINDING SITES; CELL EXTRACTS; CELL LINE; ENDOPEPTIDASES; ENZYME INHIBITORS; FUNGAL PROTEINS; GENE DELETION; IODINE RADIOISOTOPES; MACROMOLECULAR SUBSTANCES; MICE; OLIGOPEPTIDES; PEPTIDE HYDROLASES; PROTEASOME ENDOPEPTIDASE COMPLEX; SACCHAROMYCES CEREVISIAE PROTEINS; SULFONES; THIOLESTER HYDROLASES; UBIQUITIN THIOLESTERASE; UBIQUITINS; YEASTS;

EID: 0035903538     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.18.5187     Document Type: Article

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