Pancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell

Journal of Biological Chemistry

Volumn 289, Issue 47, 2014, Pages 32798-32810

  Johnson, Justin S ^a   Kono, Tatsuyoshi ^a   Tong, Xin ^a   Yamamoto, Wataru R ^a   Zarain Herzberg, Angel ^b   Merrins, Matthew J ^c   Satin, Leslie S ^d   Gilon, Patrick ^e,g   Evans Molina, Carmella ^a,f  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^f RICHARD L ROUDEBUSH VETERANS AFFAIRS MEDICAL CENTER   (United States)

^g FNRS   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; CELL MEMBRANES; CELLS; CYTOLOGY;

CHROMATIN IMMUNOPRECIPITATION; CO-TRANSFECTIONS; ENDOPLASMIC RETICULUM; FLUORESCENCE LIFETIME IMAGING MICROSCOPY; LUCIFERASE ACTIVITIES; TRANSCRIPTIONAL REGULATION; TRANSCRIPTIONAL TARGETS; WILD-TYPE CONTROLS;

CALCIUM;

CALCIUM ION; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 2B; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; ATP2A2 PROTEIN, HUMAN; ATP2A2 PROTEIN, MOUSE; CALCIUM; HOMEODOMAIN PROTEIN; PANCREATIC AND DUODENAL HOMEOBOX 1 PROTEIN; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CELL ISOLATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DIABETES MELLITUS; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; ENZYME DEFICIENCY; FLUORESCENCE IMAGING; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; INFLAMMATORY DISEASE; INS 1 CELL LINE; LIPID DIET; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RAT; TRANSCRIPTION REGULATION; 3T3 CELL LINE; ANIMAL; C57BL MOUSE; ENDOPLASMIC RETICULUM; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; IMMUNOBLOTTING; METABOLISM; MUTANT MOUSE STRAIN; PROCEDURES; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR CELL LINE;

ANIMALS; CALCIUM; CELL LINE, TUMOR; DIABETES MELLITUS; ENDOPLASMIC RETICULUM; GENE EXPRESSION; GENE EXPRESSION REGULATION; HEK293 CELLS; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOBLOTTING; INSULIN-SECRETING CELLS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICROSCOPY, FLUORESCENCE; NIH 3T3 CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; TRANS-ACTIVATORS;

EID: 84911431018     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.575191     Document Type: Article

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