Mechanisms of control of the free Ca 2+ concentration in the endoplasmic reticulum of mouse pancreatic β-cells: Interplay with cell metabolism and [Ca 2+] c and role of SERCA2b and SERCA3

Diabetes

Volumn 60, Issue 10, 2011, Pages 2533-2545

  Ravier, Magalie A ^a,b   Daro, Dorothée ^a   Roma, Leticia Prates ^a   Jonas, Jean Christophe ^a   Cheng Xue, Rui ^a   Schuit, Frans C ^c   Gilon, Patrick ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIV MONTPELLIER   (France)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CALCIUM BINDING PROTEIN; CALCIUM ION; DIAZOXIDE; GLUCOSE; INSULIN; MESSENGER RNA; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 2B; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 3; UNCLASSIFIED DRUG;

ADAPTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL METABOLISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; IMPAIRED GLUCOSE TOLERANCE; INSULIN RELEASE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; REGULATORY MECHANISM;

ANIMALS; CALCIUM; DIAZOXIDE; ENDOPLASMIC RETICULUM; GENE DELETION; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; GLUCOSE; INSULIN; INSULIN-SECRETING CELLS; MICE; MICE, KNOCKOUT; PROMOTER REGIONS, GENETIC; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; VASODILATOR AGENTS;

EID: 80053408344     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db10-1543     Document Type: Article

References (50)

1. 2+ concentration in an electrically excitable cell, the insulin-secreting pancreatic B-cell. J Biol Chem 1992;267:20713-20720
2. Rorsman P. The pancreatic beta-cell as a fuel sensor: an electrophysiologist's viewpoint. Diabetologia 1997;40:487-495 (Pubitemid 27186783)
3. Váradi A, Molnár E, Ostenson CG, Ashcroft SJ. Isoforms of endoplasmic reticulum Ca(2+)-ATPase are differentially expressed in normal and diabetic islets of Langerhans. Biochem J 1996;319:521-527
4. Arredouani A, Guiot Y, Jonas JC, et al. SERCA3 ablation does not impair insulin secretion but suggests distinct roles of different sarcoendoplasmic reticulum Ca(2+) pumps for Ca(2+) homeostasis in pancreatic beta-cells. Diabetes 2002;51:3245-3253 (Pubitemid 35246971)
5. 2+-ATPase (SERCA)-2 and ryanodine receptors. Diabetes 2002;51(Suppl. 1):S190-S201
6. Arredouani A, Henquin JC, Gilon P. Contribution of the endoplasmic reticulum to the glucose-induced [Ca(2+)](c) response in mouse pancreatic islets. Am J Physiol Endocrinol Metab 2002;282:E982-E991 (Pubitemid 34654711)
7. 2+ influx in the electrically excitable pancreatic B-cell. J Biol Chem 1999;274:20197-20205
8. Maechler P, Kennedy ED, Sebö E, Valeva A, Pozzan T, Wollheim CB. Secretagogues modulate the calcium concentration in the endoplasmic reticulum of insulin-secreting cells. Studies in aequorin-expressing intact and permeabilized ins-1 cells. J Biol Chem 1999;274:12583-12592
9. Tengholm A, Hellman B, Gylfe E. Glucose regulation of free Ca(2+) in the endoplasmic reticulum of mouse pancreatic beta cells. J Biol Chem 1999;274:36883-36890
10. 2+ release in pancreatic islet beta-cells: critical evaluation of the use of endoplasmic reticulum-targeted "cameleons". Endocrinology 2004;145:4540-4549
11. Tamarina NA, Kuznetsov A, Rhodes CJ, Bindokas VP, Philipson LH. Inositol (1,4,5)-trisphosphate dynamics and intracellular calcium oscillations in pancreatic beta-cells. Diabetes 2005;54:3073-3081 (Pubitemid 43334358)
12. 2+ channels in pancreatic beta-cells. J Biol Chem 2001;276:9971-9977
13. 2+pool in mouse pancreatic beta-cells. J Physiol 2004;559:141-156
14. 2+ in mouse pancreatic islets. J Physiol 1998;508:471-481
15. Demaurex N, Frieden M. Measurements of the free luminal ER Ca(2+) concentration with targeted "cameleon" fluorescent proteins. Cell Calcium 2003;34:109-119 (Pubitemid 36798394)
16. McCombs JE, Palmer AE. Measuring calcium dynamics in living cells with genetically encodable calcium indicators. Methods 2008;46:152-159
17. 2+channels in endoplasmic reticulum stress and beta-cell death. Diabetes 2009;58:422-432
18. 2+ depletion in adult skeletal muscle fibres measured with the biosensor D1ER. Pflugers Arch 2010;459:725-735
19. 2+ analyzed with an improved genetically encoded fluorescent sensor. Proc Natl Acad Sci USA 2004;101:17404-17409
20. 2+ indicators based on computationally redesigned calmodulin-peptide pairs. Chem Biol 2006;13:521-530
21. 2+-ATPase isoform 3. J Biol Chem 1997;272:30538-30545
22. Varadi A, Lebel L, Hashim Y, Mehta Z, Ashcroft SJ, Turner R. Sequence variants of the sarco(endo)plasmic reticulum Ca(2+)-transport ATPase 3 gene (SERCA3) in Caucasian type II diabetic patients (UK Prospective Diabetes Study 48). Diabetologia 1999;42:1240-1243 (Pubitemid 29459822)
23. Jonas JC, Sharma A, Hasenkamp W, et al. Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes. J Biol Chem 1999;274:14112-14121
24. 2+ATPase type 3 isoforms (SERCA3b and SERCA3f): distinct roles in cell adhesion and ER stress. Biochem Biophys Res Commun 2006;345:1377-1385
25. 2+]c by different mechanisms in isolated mouse alpha-cells. Diabetes 2009;58:412-421
26. Quoix N, Cheng-Xue R, Guiot Y, Herrera PL, Henquin JC, Gilon P. The GluCre-ROSA26EYFP mouse: a new model for easy identification of living pancreatic alpha-cells. FEBS Lett 2007;581:4235-4240 (Pubitemid 47301858)
27. Marhfour I, Jonas JC, Marchandise J, et al. Endoplasmic reticulum accumulation of Kir6.2 without activation of ER stress response in islet cells from adult Sur1 knockout mice. Cell Tissue Res 2010;340:335-346
28. 2+, and pH-regulating exchangers in glucose-induced rise of cytoplasmic pH in normal mouse pancreatic islets. J Biol Chem 1995;270:7915-7921
29. 2+ homeostasis revealed by RNA silencing. Diabetes 2004;53:393-400
30. 2+ in mouse pancreatic beta-cells. J Physiol 2001;530:533-540
31. 2+ release at the endoplasmic reticulum in rat pancreatic beta-cells. Cell Calcium 1995;17:21-31
32. 2+ sequestration in diabetic mouse islets of Langerhans. J Biol Chem 1994;269:18279-18282
33. Lytton J, Westlin M, Burk SE, Shull GE, MacLennan DH. Functional comparisons between isoforms of the sarcoplasmic or endoplasmic reticulum family of calcium pumps. J Biol Chem 1992;267:14483-14489
34. Dyachok O, Gylfe E. Ca(2+)-induced Ca(2+) release via inositol 1,4,5-trisphosphate receptors is amplified by protein kinase A and triggers exocytosis in pancreatic beta-cells. J Biol Chem 2004;279:45455-45461 (Pubitemid 39491530)
35. Calcraft PJ, Ruas M, Pan Z, et al. NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature 2009;459:596-600
36. 2+ and the ATP/ADP ratio: a feedback control mechanism in mouse pancreatic islets. Biochem J 1998;333:269-274
37. 2+concentration in the store lumen. EMBO J 1998;17:435-442
38. Shannon TR, Ginsburg KS, Bers DM. Reverse mode of the sarcoplasmic reticulum calcium pump and load-dependent cytosolic calcium decline in voltage-clamped cardiac ventricular myocytes. Biophys J 2000;78:322-333 (Pubitemid 30207141)
39. Putney JW. Capacitative calcium entry: from concept to molecules. Immunol Rev 2009;231:10-22
40. Henquin JC. Relative importance of extracellular and intracellular calcium for the two phases of glucose-stimulated insulin release: studies with theophylline. Endocrinology 1978;102:723-730 (Pubitemid 8306883)
41. 2+-ATPase of the endoplasmic reticulum. Am J Physiol Cell Physiol 2006;290:C1503-C1511
42. Dyachok O, Gylfe E. Store-operated influx of Ca(2+) in pancreatic beta-cells exhibits graded dependence on the filling of the endoplasmic reticulum. J Cell Sci 2001;114:2179-2186 (Pubitemid 32586642)
43. 2+ entry in mouse pancreatic beta-cells by both direct and indirect mechanisms. J Physiol 1997;503:387-398
44. Bertram R, Sherman A. Filtering of calcium transients by the endoplasmic reticulum in pancreatic beta-cells. Biophys J 2004;87:3775-3785 (Pubitemid 39602885)
45. 2+ release through the c-Jun N-terminal kinase pathway. Mol Cell Biochem 2009;324:183-190
46. 2+ stores and triggers apoptosis in insulin-secreting BRIN-BD11 cells. J Biol Chem 2010;285:30634-30643
47. 2+ is important for the proteolytic processing and intracellular transport of proinsulin in the pancreatic beta-cell. Biochem J 1997;323:445-450
48. Corbett EF, Michalak M. Calcium, a signaling molecule in the endoplasmic reticulum? Trends Biochem Sci 2000;25:307-311 (Pubitemid 30421094)
49. Ma Y, Hendershot LM. ER chaperone functions during normal and stress conditions. J Chem Neuroanat 2004;28:51-65 (Pubitemid 39195252)
50. Elouil H, Bensellam M, Guiot Y, et al. Acute nutrient regulation of the unfolded protein response and integrated stress response in cultured rat pancreatic islets. Diabetologia 2007;50:1442-1452 (Pubitemid 46879004)