Autophagy and senescence, stress responses induced by the DNA-damaging mycotoxin alternariol

Toxicology

Volumn 326, Issue , 2014, Pages 119-129

  Solhaug, A ^a   Torgersen, M L ^b,c   Holme, J A ^d   Lagadic Gossmann, D ^e,f   Eriksen, G S ^a  

^a NORWEGIAN VETERINARY INSTITUTE   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

^d NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^e UNIVERSITÉ DE RENNES 1   (France)

^f UNIVERSITÉ DE RENNES 1   (France)

Author keywords

Alternariol; Autophagy; Lamellar bodies; MTOR; Senescence; Sestrin2

Indexed keywords

ALTERNARIOL; BETA GALACTOSIDASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; NUCLEAR PROTEIN; PROTEIN P53; PROTEIN SESTRIN2; S6 KINASE; UNCLASSIFIED DRUG; LACTONE; MTOR PROTEIN, MOUSE; MYCOTOXIN; SESTRIN 2 PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ARTICLE; AUTOLYSOSOME; AUTOPHAGOSOME; AUTOPHAGY; CELL AGING; CELL STRESS; CELL STRUCTURE; CELL ULTRASTRUCTURE; CELL VACUOLE; ENZYME ACTIVITY; LAMELLAR BODY; LIPID METABOLISM; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; CELL LINE; DOSE RESPONSE; DOUBLE STRANDED DNA BREAK; DRUG EFFECTS; METABOLISM; PHYSIOLOGICAL STRESS; TIME; TOXICITY; ULTRASTRUCTURE;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; AUTOPHAGY; CELL AGING; CELL LINE; DNA BREAKS, DOUBLE-STRANDED; DOSE-RESPONSE RELATIONSHIP, DRUG; LACTONES; MACROPHAGES; MICE; MYCOTOXINS; NUCLEAR PROTEINS; RIBOSOMAL PROTEIN S6 KINASES; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TIME FACTORS; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84909606530     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2014.10.009     Document Type: Article

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