메뉴 건너뛰기




Volumn 34, Issue 22, 2014, Pages 4165-4176

Lipid droplet protein LID-1 mediates ATGL-1-dependent lipolysis during fasting in Caenorhabditis elegans

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOSE TRIGLYCERIDE LIPASE 1; BINDING PROTEIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FAT DROPLET; LIPID DROPLET PROTEIN 1; SYNAPSIN I; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; ATGL-1 PROTEIN, C ELEGANS; CAENORHABDITIS ELEGANS PROTEIN; CARRIER PROTEIN; LIPID DROPLET PROTEIN 1, C ELEGANS;

EID: 84908887645     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00722-14     Document Type: Article
Times cited : (66)

References (72)
  • 2
    • 67650305511 scopus 로고    scopus 로고
    • Caenorhabditis elegans as an emerging model for studying the basic biology of obesity
    • Jones KT, Ashrafi K. 2009. Caenorhabditis elegans as an emerging model for studying the basic biology of obesity. Dis. Model. Mech. 2:224-229. http://dx.doi.org/10.1242/dmm.001933.
    • (2009) Dis. Model. Mech , vol.2 , pp. 224-229
    • Jones, K.T.1    Ashrafi, K.2
  • 3
    • 0021686137 scopus 로고
    • Arresting development arrests aging in the nematode Caenorhabditis elegans
    • Johnson TE, Mitchell DH, Kline S, Kemal R, Foy J. 1984. Arresting development arrests aging in the nematode Caenorhabditis elegans. Mech. Ageing Dev. 28:23-40. http://dx.doi.org/10.1016/0047-6374(84) 90150-7.
    • (1984) Mech. Ageing Dev , vol.28 , pp. 23-40
    • Johnson, T.E.1    Mitchell, D.H.2    Kline, S.3    Kemal, R.4    Foy, J.5
  • 4
    • 0016766716 scopus 로고
    • The dauerlarva, a post-embryonic developmental variant of the nematode Caenorhabditis elegans
    • Cassada RC, Russell RL. 1975. The dauerlarva, a post-embryonic developmental variant of the nematode Caenorhabditis elegans. Dev. Biol. 46: 326-342. http://dx.doi.org/10.1016/0012-1606(75)90109-8.
    • (1975) Dev. Biol , vol.46 , pp. 326-342
    • Cassada, R.C.1    Russell, R.L.2
  • 5
    • 0021418719 scopus 로고
    • The Caenorhabditis elegans dauer larva: developmental effects of pheromone, food, and temperature
    • Golden JW, Riddle DL. 1984. The Caenorhabditis elegans dauer larva: developmental effects of pheromone, food, and temperature. Dev. Biol. 102:368-378. http://dx.doi.org/10.1016/0012-1606(84)90201-X.
    • (1984) Dev. Biol , vol.102 , pp. 368-378
    • Golden, J.W.1    Riddle, D.L.2
  • 6
    • 26444442036 scopus 로고    scopus 로고
    • A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49
    • Van Gilst MR, Hadjivassiliou H, Yamamoto KR. 2005. A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49. Proc. Natl. Acad. Sci. U. S. A. 102:13496-13501. http://dx.doi.org/10.1073/pnas.0506234102.
    • (2005) Proc. Natl. Acad. Sci. U. S. A , vol.102 , pp. 13496-13501
    • Van Gilst, M.R.1    Hadjivassiliou, H.2    Yamamoto, K.R.3
  • 7
    • 0033714116 scopus 로고    scopus 로고
    • C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway
    • Sawin ER, Ranganathan R, Horvitz HR. 2000. C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway. Neuron 26:619-631. http://dx.doi.org/10.1016/S0896-6273(00)81199-X.
    • (2000) Neuron , vol.26 , pp. 619-631
    • Sawin, E.R.1    Ranganathan, R.2    Horvitz, H.R.3
  • 8
    • 0025063432 scopus 로고
    • Effects of starvation and neuroactive drugs on feeding in Caenorhabditis elegans
    • Avery L, Horvitz HR. 1990. Effects of starvation and neuroactive drugs on feeding in Caenorhabditis elegans. J. Exp. Zool. 253:263-270. http://dx.doi.org/10.1002/jez.1402530305.
    • (1990) J. Exp. Zool , vol.253 , pp. 263-270
    • Avery, L.1    Horvitz, H.R.2
  • 9
    • 72449170138 scopus 로고    scopus 로고
    • Starvation protects germline stem cells and extends reproductive longevity in C. elegans
    • Angelo G, Van Gilst MR. 2009. Starvation protects germline stem cells and extends reproductive longevity in C. elegans. Science 326:954-958. http://dx.doi.org/10.1126/science.1178343.
    • (2009) Science , vol.326 , pp. 954-958
    • Angelo, G.1    Van Gilst, M.R.2
  • 11
    • 0019977293 scopus 로고
    • Serotonin and octopamine in the nematode Caenorhabditis elegans
    • Horvitz HR, Chalfie M, Trent C, Sulston JE, Evans PD. 1982. Serotonin and octopamine in the nematode Caenorhabditis elegans. Science 216: 1012-1014. http://dx.doi.org/10.1126/science.6805073.
    • (1982) Science , vol.216 , pp. 1012-1014
    • Horvitz, H.R.1    Chalfie, M.2    Trent, C.3    Sulston, J.E.4    Evans, P.D.5
  • 12
    • 0037237117 scopus 로고    scopus 로고
    • C. elegans: a model for exploring the genetics of fat storage
    • McKay RM, McKay JP, Avery L, Graff JM. 2003. C. elegans: a model for exploring the genetics of fat storage. Dev. Cell 4:131-142. http://dx.doi.org/10.1016/S1534-5807(02)00411-2.
    • (2003) Dev. Cell , vol.4 , pp. 131-142
    • McKay, R.M.1    McKay, J.P.2    Avery, L.3    Graff, J.M.4
  • 13
    • 10644282295 scopus 로고    scopus 로고
    • The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans
    • Apfeld J, O'Connor G, McDonagh T, DiStefano PS, Curtis R. 2004. The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans. Genes Dev. 18:3004-3009. http://dx.doi.org/10.1101/gad.1255404.
    • (2004) Genes Dev , vol.18 , pp. 3004-3009
    • Apfeld, J.1    O'Connor, G.2    McDonagh, T.3    DiStefano, P.S.4    Curtis, R.5
  • 15
    • 4544311861 scopus 로고    scopus 로고
    • The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
    • Jia K, Chen D, Riddle DL. 2004. The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development 131:3897-3906. http://dx.doi.org/10.1242/dev.01255.
    • (2004) Development , vol.131 , pp. 3897-3906
    • Jia, K.1    Chen, D.2    Riddle, D.L.3
  • 18
    • 33646168160 scopus 로고    scopus 로고
    • Lipid droplets: a unified view of a dynamic organelle
    • Martin S, Parton RG. 2006. Lipid droplets: a unified view of a dynamic organelle. Nat. Rev. Mol. Cell Biol. 7:373-378. http://dx.doi.org/10.1038/nrm1912.
    • (2006) Nat. Rev. Mol. Cell Biol , vol.7 , pp. 373-378
    • Martin, S.1    Parton, R.G.2
  • 19
    • 33748598240 scopus 로고    scopus 로고
    • The lipid-droplet proteome reveals that droplets are a protein-storage depot
    • Cermelli S, Guo Y, Gross SP, Welte MA. 2006. The lipid-droplet proteome reveals that droplets are a protein-storage depot. Curr. Biol. 16: 1783-1795. http://dx.doi.org/10.1016/j.cub.2006.07.062.
    • (2006) Curr. Biol , vol.16 , pp. 1783-1795
    • Cermelli, S.1    Guo, Y.2    Gross, S.P.3    Welte, M.A.4
  • 20
    • 8744267532 scopus 로고    scopus 로고
    • Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes
    • Brasaemle DL, Dolios G, Shapiro L, Wang R. 2004. Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes. J. Biol. Chem. 279:46835-46842. http://dx.doi.org/10.1074/jbc.M409340200.
    • (2004) J. Biol. Chem , vol.279 , pp. 46835-46842
    • Brasaemle, D.L.1    Dolios, G.2    Shapiro, L.3    Wang, R.4
  • 21
    • 0037200026 scopus 로고    scopus 로고
    • Functional conservation for lipid storage droplet association among Perilipin, ADRP, and TIP47 (PAT)-related proteins in mammals, Drosophila, and Dictyostelium
    • Miura S, Gan JW, Brzostowski J, Parisi MJ, Schultz CJ, Londos C, Oliver B, Kimmel AR. 2002. Functional conservation for lipid storage droplet association among Perilipin, ADRP, and TIP47 (PAT)-related proteins in mammals, Drosophila, and Dictyostelium. J. Biol. Chem. 277: 32253-32257. http://dx.doi.org/10.1074/jbc.M204410200.
    • (2002) J. Biol. Chem , vol.277 , pp. 32253-32257
    • Miura, S.1    Gan, J.W.2    Brzostowski, J.3    Parisi, M.J.4    Schultz, C.J.5    Londos, C.6    Oliver, B.7    Kimmel, A.R.8
  • 22
    • 36649015243 scopus 로고    scopus 로고
    • Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis
    • Brasaemle DL. 2007. Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis. J. Lipid Res. 48:2547-2559. http://dx.doi.org/10.1194/jlr.R700014-JLR200.
    • (2007) J. Lipid Res , vol.48 , pp. 2547-2559
    • Brasaemle, D.L.1
  • 24
    • 0037477829 scopus 로고    scopus 로고
    • Perilipin A is essential for the translocation of hormonesensitive lipase during lipolytic activation
    • Sztalryd C, Xu G, Dorward H, Tansey JT, Contreras JA, Kimmel AR, Londos C. 2003. Perilipin A is essential for the translocation of hormonesensitive lipase during lipolytic activation. J. Cell Biol. 161:1093-1103. http://dx.doi.org/10.1083/jcb.200210169.
    • (2003) J. Cell Biol , vol.161 , pp. 1093-1103
    • Sztalryd, C.1    Xu, G.2    Dorward, H.3    Tansey, J.T.4    Contreras, J.A.5    Kimmel, A.R.6    Londos, C.7
  • 27
    • 3142738035 scopus 로고    scopus 로고
    • CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome
    • Yamaguchi T, Omatsu N, Matsushita S, Osumi T. 2004. CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome. J. Biol. Chem. 279:30490-30497. http://dx.doi.org/10.1074/jbc.M403920200.
    • (2004) J. Biol. Chem , vol.279 , pp. 30490-30497
    • Yamaguchi, T.1    Omatsu, N.2    Matsushita, S.3    Osumi, T.4
  • 28
    • 71749098785 scopus 로고    scopus 로고
    • Perilipin controls lipolysis by regulating the interactions of AB-hydrolase containing 5 (Abhd5) and adipose triglyceride lipase (Atgl)
    • Granneman JG, Moore HP, Krishnamoorthy R, Rathod M. 2009. Perilipin controls lipolysis by regulating the interactions of AB-hydrolase containing 5 (Abhd5) and adipose triglyceride lipase (Atgl). J. Biol. Chem. 284:34538-34544. http://dx.doi.org/10.1074/jbc.M109.068478.
    • (2009) J. Biol. Chem , vol.284 , pp. 34538-34544
    • Granneman, J.G.1    Moore, H.P.2    Krishnamoorthy, R.3    Rathod, M.4
  • 29
    • 33847714769 scopus 로고    scopus 로고
    • Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes
    • Miyoshi H, Perfield JW, II, Souza SC, Shen WJ, Zhang HH, Stancheva ZS, Kraemer FB, Obin MS, Greenberg AS. 2007. Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes. J. Biol. Chem. 282: 996-1002. http://dx.doi.org/10.1074/jbc.M605770200.
    • (2007) J. Biol. Chem , vol.282 , pp. 996-1002
    • Miyoshi, H.1    Perfield II, J.W.2    Souza, S.C.3    Shen, W.J.4    Zhang, H.H.5    Stancheva, Z.S.6    Kraemer, F.B.7    Obin, M.S.8    Greenberg, A.S.9
  • 30
    • 29044440372 scopus 로고    scopus 로고
    • Signalling mechanisms regulating lipolysis
    • Carmen GY, Victor SM. 2006. Signalling mechanisms regulating lipolysis. Cell. Signal. 18:401-408. http://dx.doi.org/10.1016/j.cellsig.2005.08.009.
    • (2006) Cell. Signal , vol.18 , pp. 401-408
    • Carmen, G.Y.1    Victor, S.M.2
  • 31
    • 76049091112 scopus 로고    scopus 로고
    • Lipid homeostasis, lipotoxicity and the metabolic syndrome
    • Unger RH, Clark GO, Scherer PE, Orci L. 2010. Lipid homeostasis, lipotoxicity and the metabolic syndrome. Biochim. Biophys. Acta 1801: 209-214. http://dx.doi.org/10.1016/j.bbalip.2009.10.006.
    • (2010) Biochim. Biophys. Acta , vol.1801 , pp. 209-214
    • Unger, R.H.1    Clark, G.O.2    Scherer, P.E.3    Orci, L.4
  • 32
    • 58149339613 scopus 로고    scopus 로고
    • Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival
    • Narbonne P, Roy R. 2009. Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival. Nature 457: 210-214. http://dx.doi.org/10.1038/nature07536.
    • (2009) Nature , vol.457 , pp. 210-214
    • Narbonne, P.1    Roy, R.2
  • 33
    • 55849101681 scopus 로고    scopus 로고
    • Fat metabolism links germline stem cells and longevity in C
    • Wang MC, O'Rourke EJ, Ruvkun G. 2008. Fat metabolism links germline stem cells and longevity in C. elegans. Science 322:957-960. http://dx.doi.org/10.1126/science.1162011.
    • (2008) elegans. Science , vol.322 , pp. 957-960
    • Wang, M.C.1    O'Rourke, E.J.2    Ruvkun, G.3
  • 34
    • 84874271499 scopus 로고    scopus 로고
    • w-6 polyunsaturated fatty acids extend life span through the activation of autophagy
    • O'Rourke EJ, Kuballa P, Xavier R, Ruvkun G. 2013. w-6 polyunsaturated fatty acids extend life span through the activation of autophagy. Genes Dev. 27:429-440. http://dx.doi.org/10.1101/gad.205294.112.
    • (2013) Genes Dev , vol.27 , pp. 429-440
    • O'Rourke, E.J.1    Kuballa, P.2    Xavier, R.3    Ruvkun, G.4
  • 35
    • 84878533962 scopus 로고    scopus 로고
    • MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
    • O'Rourke EJ, Ruvkun G. 2013. MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability. Nat. Cell Biol. 15: 668-676. http://dx.doi.org/10.1038/ncb2741.
    • (2013) Nat. Cell Biol , vol.15 , pp. 668-676
    • O'Rourke, E.J.1    Ruvkun, G.2
  • 36
    • 65349113758 scopus 로고    scopus 로고
    • IRE-1 and HSP-4 contribute to energy homeostasis via fasting-induced lipases in C
    • Jo H, Shim J, Lee JH, Lee J, Kim JB. 2009. IRE-1 and HSP-4 contribute to energy homeostasis via fasting-induced lipases in C. elegans. Cell Metab. 9:440-448. http://dx.doi.org/10.1016/j.cmet.2009.04.004.
    • (2009) elegans. Cell Metab , vol.9 , pp. 440-448
    • Jo, H.1    Shim, J.2    Lee, J.H.3    Lee, J.4    Kim, J.B.5
  • 37
    • 70350365111 scopus 로고    scopus 로고
    • C. elegans major fats are stored in vesicles distinct from lysosome-related organelles
    • O'Rourke EJ, Soukas AA, Carr CE, Ruvkun G. 2009. C. elegans major fats are stored in vesicles distinct from lysosome-related organelles. Cell Metab. 10:430-435. http://dx.doi.org/10.1016/j.cmet.2009.10.002.
    • (2009) Cell Metab , vol.10 , pp. 430-435
    • O'Rourke, E.J.1    Soukas, A.A.2    Carr, C.E.3    Ruvkun, G.4
  • 39
    • 70449560405 scopus 로고    scopus 로고
    • The influence of bacterial diet on fat storage in C
    • Brooks KK, Liang B, Watts JL. 2009. The influence of bacterial diet on fat storage in C. elegans. PLoS One 4:e7545. http://dx.doi.org/10.1371/journal.pone.0007545.
    • (2009) elegans. PLoS One , vol.4 , pp. e7545
    • Brooks, K.K.1    Liang, B.2    Watts, J.L.3
  • 40
    • 61449244533 scopus 로고    scopus 로고
    • Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans
    • Soukas AA, Kane EA, Carr CE, Melo JA, Ruvkun G. 2009. Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans. Genes Dev. 23:496-511. http://dx.doi.org/10.1101/gad.1775409.
    • (2009) Genes Dev , vol.23 , pp. 496-511
    • Soukas, A.A.1    Kane, E.A.2    Carr, C.E.3    Melo, J.A.4    Ruvkun, G.5
  • 42
    • 33745612095 scopus 로고    scopus 로고
    • Pvclust: an R package for assessing the uncertainty in hierarchical clustering
    • Suzuki R, Shimodaira H. 2006. Pvclust: an R package for assessing the uncertainty in hierarchical clustering. Bioinformatics 22:1540-1542. http://dx.doi.org/10.1093/bioinformatics/btl117.
    • (2006) Bioinformatics , vol.22 , pp. 1540-1542
    • Suzuki, R.1    Shimodaira, H.2
  • 43
    • 34548755067 scopus 로고    scopus 로고
    • Assay of protein kinases using radiolabeled ATP: a protocol
    • Hastie CJ, McLauchlan HJ, Cohen P. 2006. Assay of protein kinases using radiolabeled ATP: a protocol. Nat. Protoc. 1:968-971. http://dx.doi.org/10.1038/nprot.2006.149.
    • (2006) Nat. Protoc , vol.1 , pp. 968-971
    • Hastie, C.J.1    McLauchlan, H.J.2    Cohen, P.3
  • 44
    • 84905040517 scopus 로고    scopus 로고
    • Comparative gene identification 58/alpha/beta hydrolase domain 5 lacks lysophosphatidic acid acyltransferase activity
    • McMahon D, Dinh A, Kurz D, Shah D, Han GS, Carman GM, Brasaemle DL. 2014. Comparative gene identification 58/alpha/beta hydrolase domain 5 lacks lysophosphatidic acid acyltransferase activity. J. Lipid Res. 55:1750-1761. http://dx.doi.org/10.1194/jlr.M051151.
    • (2014) J. Lipid Res , vol.55 , pp. 1750-1761
    • McMahon, D.1    Dinh, A.2    Kurz, D.3    Shah, D.4    Han, G.S.5    Carman, G.M.6    Brasaemle, D.L.7
  • 45
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ. 1959. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37:911-917. http://dx.doi.org/10.1139/o59-099.
    • (1959) Can. J. Biochem. Physiol , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 49
    • 54049155777 scopus 로고    scopus 로고
    • CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid
    • Ghosh AK, Ramakrishnan G, Chandramohan C, Rajasekharan R. 2008. CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid. J. Biol. Chem. 283:24525-24533. http://dx.doi.org/10.1074/jbc.M801783200.
    • (2008) J. Biol. Chem , vol.283 , pp. 24525-24533
    • Ghosh, A.K.1    Ramakrishnan, G.2    Chandramohan, C.3    Rajasekharan, R.4
  • 51
    • 0025131925 scopus 로고
    • Characterization of Escherichia coli cells deficient in 1-acyl-sn-glycerol-3-phosphate acyltransferase activity
    • Coleman J. 1990. Characterization of Escherichia coli cells deficient in 1-acyl-sn-glycerol-3-phosphate acyltransferase activity. J. Biol. Chem. 265:17215-17221.
    • (1990) J. Biol. Chem , vol.265 , pp. 17215-17221
    • Coleman, J.1
  • 52
    • 84858782079 scopus 로고    scopus 로고
    • AMPK: a nutrient and energy sensor that maintains energy homeostasis
    • Hardie DG, Ross FA, Hawley SA. 2012. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat. Rev. Mol. Cell Biol. 13: 251-262. http://dx.doi.org/10.1038/nrm3311.
    • (2012) Nat. Rev. Mol. Cell Biol , vol.13 , pp. 251-262
    • Hardie, D.G.1    Ross, F.A.2    Hawley, S.A.3
  • 53
    • 47249157348 scopus 로고    scopus 로고
    • The Caenorhabditis elegans AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and is required for resistance to oxidative stress and for normal motility and foraging behavior
    • Lee H, Cho JS, Lambacher N, Lee J, Lee SJ, Lee TH, Gartner A, Koo HS. 2008. The Caenorhabditis elegans AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and is required for resistance to oxidative stress and for normal motility and foraging behavior. J. Biol. Chem. 283:14988-14993 http://dx.doi.org/10.1074/jbc.M709115200.
    • (2008) J. Biol. Chem , vol.283 , pp. 14988-14993
    • Lee, H.1    Cho, J.S.2    Lambacher, N.3    Lee, J.4    Lee, S.J.5    Lee, T.H.6    Gartner, A.7    Koo, H.S.8
  • 54
    • 15544390526 scopus 로고    scopus 로고
    • Mutations that rescue the paralysis of Caenorhabditis elegans ric-8 (synembryn) mutants activate the G alpha(s) pathway and define a third major branch of the synaptic signaling network
    • Schade MA, Reynolds NK, Dollins CM, Miller KG. 2005. Mutations that rescue the paralysis of Caenorhabditis elegans ric-8 (synembryn) mutants activate the G alpha(s) pathway and define a third major branch of the synaptic signaling network. Genetics 169:631-649. http://dx.doi.org/10.1534/genetics.104.032334.
    • (2005) Genetics , vol.169 , pp. 631-649
    • Schade, M.A.1    Reynolds, N.K.2    Dollins, C.M.3    Miller, K.G.4
  • 55
    • 84865420340 scopus 로고    scopus 로고
    • Identification and functional characterization of protein kinase A phosphorylation sites in the major lipolytic protein, adipose triglyceride lipase
    • Pagnon J, Matzaris M, Stark R, Meex RC, Macaulay SL, Brown W, O'Brien PE, Tiganis T, Watt MJ. 2012. Identification and functional characterization of protein kinase A phosphorylation sites in the major lipolytic protein, adipose triglyceride lipase. Endocrinology 153:4278-4289. http://dx.doi.org/10.1210/en.2012-1127.
    • (2012) Endocrinology , vol.153 , pp. 4278-4289
    • Pagnon, J.1    Matzaris, M.2    Stark, R.3    Meex, R.C.4    Macaulay, S.L.5    Brown, W.6    O'Brien, P.E.7    Tiganis, T.8    Watt, M.J.9
  • 63
    • 33644764922 scopus 로고    scopus 로고
    • Adipose triglyceride lipase: function, regulation by insulin, and comparison with adiponutrin
    • Kershaw EE, Hamm JK, Verhagen LA, Peroni O, Katic M, Flier JS. 2006. Adipose triglyceride lipase: function, regulation by insulin, and comparison with adiponutrin. Diabetes 55:148-157. http://dx.doi.org/10.2337/diabetes.55.01.06.db05-0982.
    • (2006) Diabetes , vol.55 , pp. 148-157
    • Kershaw, E.E.1    Hamm, J.K.2    Verhagen, L.A.3    Peroni, O.4    Katic, M.5    Flier, J.S.6
  • 64
    • 8744297386 scopus 로고    scopus 로고
    • Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis
    • Villena JA, Roy S, Sarkadi-Nagy E, Kim KH, Sul HS. 2004. Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis. J. Biol. Chem. 279:47066-47075. http://dx.doi.org/10.1074/jbc.M403855200.
    • (2004) J. Biol. Chem , vol.279 , pp. 47066-47075
    • Villena, J.A.1    Roy, S.2    Sarkadi-Nagy, E.3    Kim, K.H.4    Sul, H.S.5
  • 65
    • 58149308056 scopus 로고    scopus 로고
    • Cdk1/Cdc28-dependent activation of the major triacylglycerol lipase Tgl4 in yeast links lipolysis to cell-cycle progression
    • Kurat CF, Wolinski H, Petschnigg J, Kaluarachchi S, Andrews B, Natter K, Kohlwein SD. 2009. Cdk1/Cdc28-dependent activation of the major triacylglycerol lipase Tgl4 in yeast links lipolysis to cell-cycle progression. Mol. Cell 33:53-63. http://dx.doi.org/10.1016/j.molcel.2008.12.019.
    • (2009) Mol. Cell , vol.33 , pp. 53-63
    • Kurat, C.F.1    Wolinski, H.2    Petschnigg, J.3    Kaluarachchi, S.4    Andrews, B.5    Natter, K.6    Kohlwein, S.D.7
  • 66
    • 0026783771 scopus 로고
    • Mechanism of hormone-stimulated lipolysis in adipocytes: translocation of hormone-sensitive lipase to the lipid storage droplet
    • Egan JJ, Greenberg AS, Chang MK, Wek SA, Moos MC, Jr, Londos C. 1992. Mechanism of hormone-stimulated lipolysis in adipocytes: translocation of hormone-sensitive lipase to the lipid storage droplet. Proc. Natl. Acad. Sci. U. S. A. 89:8537-8541. http://dx.doi.org/10.1073/pnas.89.18.8537.
    • (1992) Proc. Natl. Acad. Sci. U. S. A , vol.89 , pp. 8537-8541
    • Egan, J.J.1    Greenberg, A.S.2    Chang, M.K.3    Wek, S.A.4    Moos Jr., M.C.5    Londos, C.6
  • 67
    • 84881261968 scopus 로고    scopus 로고
    • Dual regulation of adipose triglyceride lipase by pigment epithelium-derived factor: a novel mechanistic insight into progressive obesity
    • Dai Z, Qi W, Li C, Lu J, Mao Y, Yao Y, Li L, Zhang T, Hong H, Li S, Zhou T, Yang Z, Yang X, Gao G, Cai W. 2013. Dual regulation of adipose triglyceride lipase by pigment epithelium-derived factor: a novel mechanistic insight into progressive obesity. Mol. Cell. Endocrinol. 377:123-134. http://dx.doi.org/10.1016/j.mce.2013.07.001.
    • (2013) Mol. Cell. Endocrinol , vol.377 , pp. 123-134
    • Dai, Z.1    Qi, W.2    Li, C.3    Lu, J.4    Mao, Y.5    Yao, Y.6    Li, L.7    Zhang, T.8    Hong, H.9    Li, S.10    Zhou, T.11    Yang, Z.12    Yang, X.13    Gao, G.14    Cai, W.15
  • 68
    • 84872840929 scopus 로고    scopus 로고
    • Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover
    • Olzmann JA, Richter CM, Kopito RR. 2013. Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover. Proc. Natl. Acad. Sci. U. S. A. 110:1345-1350. http://dx.doi.org/10.1073/pnas.1213738110.
    • (2013) Proc. Natl. Acad. Sci. U. S. A , vol.110 , pp. 1345-1350
    • Olzmann, J.A.1    Richter, C.M.2    Kopito, R.R.3
  • 69
    • 84887449305 scopus 로고    scopus 로고
    • An integrated serotonin and octopamine neuronal circuit directs the release of an endocrine signal to control C
    • Noble T, Stieglitz J, Srinivasan S. 2013. An integrated serotonin and octopamine neuronal circuit directs the release of an endocrine signal to control C. elegans body fat. Cell Metab. 18:672-684. http://dx.doi.org/10.1016/j.cmet.2013.09.007.
    • (2013) elegans body fat. Cell Metab , vol.18 , pp. 672-684
    • Noble, T.1    Stieglitz, J.2    Srinivasan, S.3
  • 70
    • 80052756899 scopus 로고    scopus 로고
    • Insulin/IGF-1 receptor signaling enhances biosynthetic activity and fat mobilization in the initial phase of starvation in adult male C
    • Tan KT, Luo SC, Ho WZ, Lee YH. 2011. Insulin/IGF-1 receptor signaling enhances biosynthetic activity and fat mobilization in the initial phase of starvation in adult male C. elegans. Cell Metab. 14:390-402. http://dx.doi.org/10.1016/j.cmet.2011.06.019.
    • (2011) elegans. Cell Metab , vol.14 , pp. 390-402
    • Tan, K.T.1    Luo, S.C.2    Ho, W.Z.3    Lee, Y.H.4
  • 71
    • 47749085114 scopus 로고    scopus 로고
    • AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance
    • Gauthier MS, Miyoshi H, Souza SC, Cacicedo JM, Saha AK, Greenberg AS, Ruderman NB. 2008. AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance. J. Biol. Chem. 283:16514-16524. http://dx.doi.org/10.1074/jbc.M708177200.
    • (2008) J. Biol. Chem , vol.283 , pp. 16514-16524
    • Gauthier, M.S.1    Miyoshi, H.2    Souza, S.C.3    Cacicedo, J.M.4    Saha, A.K.5    Greenberg, A.S.6    Ruderman, N.B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.