-
1
-
-
0037448528
-
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
-
Ashrafi K, Chang FY, Watts JL, Fraser AG, Kamath RS, Ahringer J, Ruvkun G. 2003. Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 421:268-272. http://dx.doi.org/10.1038/nature01279.
-
(2003)
Nature
, vol.421
, pp. 268-272
-
-
Ashrafi, K.1
Chang, F.Y.2
Watts, J.L.3
Fraser, A.G.4
Kamath, R.S.5
Ahringer, J.6
Ruvkun, G.7
-
2
-
-
67650305511
-
Caenorhabditis elegans as an emerging model for studying the basic biology of obesity
-
Jones KT, Ashrafi K. 2009. Caenorhabditis elegans as an emerging model for studying the basic biology of obesity. Dis. Model. Mech. 2:224-229. http://dx.doi.org/10.1242/dmm.001933.
-
(2009)
Dis. Model. Mech
, vol.2
, pp. 224-229
-
-
Jones, K.T.1
Ashrafi, K.2
-
3
-
-
0021686137
-
Arresting development arrests aging in the nematode Caenorhabditis elegans
-
Johnson TE, Mitchell DH, Kline S, Kemal R, Foy J. 1984. Arresting development arrests aging in the nematode Caenorhabditis elegans. Mech. Ageing Dev. 28:23-40. http://dx.doi.org/10.1016/0047-6374(84) 90150-7.
-
(1984)
Mech. Ageing Dev
, vol.28
, pp. 23-40
-
-
Johnson, T.E.1
Mitchell, D.H.2
Kline, S.3
Kemal, R.4
Foy, J.5
-
4
-
-
0016766716
-
The dauerlarva, a post-embryonic developmental variant of the nematode Caenorhabditis elegans
-
Cassada RC, Russell RL. 1975. The dauerlarva, a post-embryonic developmental variant of the nematode Caenorhabditis elegans. Dev. Biol. 46: 326-342. http://dx.doi.org/10.1016/0012-1606(75)90109-8.
-
(1975)
Dev. Biol
, vol.46
, pp. 326-342
-
-
Cassada, R.C.1
Russell, R.L.2
-
5
-
-
0021418719
-
The Caenorhabditis elegans dauer larva: developmental effects of pheromone, food, and temperature
-
Golden JW, Riddle DL. 1984. The Caenorhabditis elegans dauer larva: developmental effects of pheromone, food, and temperature. Dev. Biol. 102:368-378. http://dx.doi.org/10.1016/0012-1606(84)90201-X.
-
(1984)
Dev. Biol
, vol.102
, pp. 368-378
-
-
Golden, J.W.1
Riddle, D.L.2
-
6
-
-
26444442036
-
A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49
-
Van Gilst MR, Hadjivassiliou H, Yamamoto KR. 2005. A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49. Proc. Natl. Acad. Sci. U. S. A. 102:13496-13501. http://dx.doi.org/10.1073/pnas.0506234102.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A
, vol.102
, pp. 13496-13501
-
-
Van Gilst, M.R.1
Hadjivassiliou, H.2
Yamamoto, K.R.3
-
7
-
-
0033714116
-
C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway
-
Sawin ER, Ranganathan R, Horvitz HR. 2000. C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway. Neuron 26:619-631. http://dx.doi.org/10.1016/S0896-6273(00)81199-X.
-
(2000)
Neuron
, vol.26
, pp. 619-631
-
-
Sawin, E.R.1
Ranganathan, R.2
Horvitz, H.R.3
-
8
-
-
0025063432
-
Effects of starvation and neuroactive drugs on feeding in Caenorhabditis elegans
-
Avery L, Horvitz HR. 1990. Effects of starvation and neuroactive drugs on feeding in Caenorhabditis elegans. J. Exp. Zool. 253:263-270. http://dx.doi.org/10.1002/jez.1402530305.
-
(1990)
J. Exp. Zool
, vol.253
, pp. 263-270
-
-
Avery, L.1
Horvitz, H.R.2
-
9
-
-
72449170138
-
Starvation protects germline stem cells and extends reproductive longevity in C. elegans
-
Angelo G, Van Gilst MR. 2009. Starvation protects germline stem cells and extends reproductive longevity in C. elegans. Science 326:954-958. http://dx.doi.org/10.1126/science.1178343.
-
(2009)
Science
, vol.326
, pp. 954-958
-
-
Angelo, G.1
Van Gilst, M.R.2
-
11
-
-
0019977293
-
Serotonin and octopamine in the nematode Caenorhabditis elegans
-
Horvitz HR, Chalfie M, Trent C, Sulston JE, Evans PD. 1982. Serotonin and octopamine in the nematode Caenorhabditis elegans. Science 216: 1012-1014. http://dx.doi.org/10.1126/science.6805073.
-
(1982)
Science
, vol.216
, pp. 1012-1014
-
-
Horvitz, H.R.1
Chalfie, M.2
Trent, C.3
Sulston, J.E.4
Evans, P.D.5
-
12
-
-
0037237117
-
C. elegans: a model for exploring the genetics of fat storage
-
McKay RM, McKay JP, Avery L, Graff JM. 2003. C. elegans: a model for exploring the genetics of fat storage. Dev. Cell 4:131-142. http://dx.doi.org/10.1016/S1534-5807(02)00411-2.
-
(2003)
Dev. Cell
, vol.4
, pp. 131-142
-
-
McKay, R.M.1
McKay, J.P.2
Avery, L.3
Graff, J.M.4
-
13
-
-
10644282295
-
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans
-
Apfeld J, O'Connor G, McDonagh T, DiStefano PS, Curtis R. 2004. The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans. Genes Dev. 18:3004-3009. http://dx.doi.org/10.1101/gad.1255404.
-
(2004)
Genes Dev
, vol.18
, pp. 3004-3009
-
-
Apfeld, J.1
O'Connor, G.2
McDonagh, T.3
DiStefano, P.S.4
Curtis, R.5
-
14
-
-
33747053907
-
An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis
-
Yang F, Vought BW, Satterlee JS, Walker AK, Jim Sun ZY, Watts JL, DeBeaumont R, Saito RM, Hyberts SG, Yang S, Macol C, Iyer L, Tjian R, van den Heuvel S, Hart AC, Wagner G, Naar AM. 2006. An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis. Nature 442:700-704. http://dx.doi.org/10.1038/nature04942.
-
(2006)
Nature
, vol.442
, pp. 700-704
-
-
Yang, F.1
Vought, B.W.2
Satterlee, J.S.3
Walker, A.K.4
Jim Sun, Z.Y.5
Watts, J.L.6
DeBeaumont, R.7
Saito, R.M.8
Hyberts, S.G.9
Yang, S.10
Macol, C.11
Iyer, L.12
Tjian, R.13
van den Heuvel, S.14
Hart, A.C.15
Wagner, G.16
Naar, A.M.17
-
15
-
-
4544311861
-
The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
-
Jia K, Chen D, Riddle DL. 2004. The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development 131:3897-3906. http://dx.doi.org/10.1242/dev.01255.
-
(2004)
Development
, vol.131
, pp. 3897-3906
-
-
Jia, K.1
Chen, D.2
Riddle, D.L.3
-
16
-
-
35748954800
-
Regulation of lipolysis in adipocytes
-
Duncan RE, Ahmadian M, Jaworski K, Sarkadi-Nagy E, Sul HS. 2007. Regulation of lipolysis in adipocytes. Annu. Rev. Nutr. 27:79-101. http://dx.doi.org/10.1146/annurev.nutr.27.061406.093734.
-
(2007)
Annu. Rev. Nutr
, vol.27
, pp. 79-101
-
-
Duncan, R.E.1
Ahmadian, M.2
Jaworski, K.3
Sarkadi-Nagy, E.4
Sul, H.S.5
-
17
-
-
84858020291
-
FAT SIGNALS-lipases and lipolysis in lipid metabolism and signaling
-
Zechner R, Zimmermann R, Eichmann TO, Kohlwein SD, Haemmerle G, Lass A, Madeo F. 2012. FAT SIGNALS-lipases and lipolysis in lipid metabolism and signaling. Cell Metab. 15:279-291. http://dx.doi.org/10.1016/j.cmet.2011.12.018.
-
(2012)
Cell Metab
, vol.15
, pp. 279-291
-
-
Zechner, R.1
Zimmermann, R.2
Eichmann, T.O.3
Kohlwein, S.D.4
Haemmerle, G.5
Lass, A.6
Madeo, F.7
-
18
-
-
33646168160
-
Lipid droplets: a unified view of a dynamic organelle
-
Martin S, Parton RG. 2006. Lipid droplets: a unified view of a dynamic organelle. Nat. Rev. Mol. Cell Biol. 7:373-378. http://dx.doi.org/10.1038/nrm1912.
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
, pp. 373-378
-
-
Martin, S.1
Parton, R.G.2
-
19
-
-
33748598240
-
The lipid-droplet proteome reveals that droplets are a protein-storage depot
-
Cermelli S, Guo Y, Gross SP, Welte MA. 2006. The lipid-droplet proteome reveals that droplets are a protein-storage depot. Curr. Biol. 16: 1783-1795. http://dx.doi.org/10.1016/j.cub.2006.07.062.
-
(2006)
Curr. Biol
, vol.16
, pp. 1783-1795
-
-
Cermelli, S.1
Guo, Y.2
Gross, S.P.3
Welte, M.A.4
-
20
-
-
8744267532
-
Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes
-
Brasaemle DL, Dolios G, Shapiro L, Wang R. 2004. Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes. J. Biol. Chem. 279:46835-46842. http://dx.doi.org/10.1074/jbc.M409340200.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 46835-46842
-
-
Brasaemle, D.L.1
Dolios, G.2
Shapiro, L.3
Wang, R.4
-
21
-
-
0037200026
-
Functional conservation for lipid storage droplet association among Perilipin, ADRP, and TIP47 (PAT)-related proteins in mammals, Drosophila, and Dictyostelium
-
Miura S, Gan JW, Brzostowski J, Parisi MJ, Schultz CJ, Londos C, Oliver B, Kimmel AR. 2002. Functional conservation for lipid storage droplet association among Perilipin, ADRP, and TIP47 (PAT)-related proteins in mammals, Drosophila, and Dictyostelium. J. Biol. Chem. 277: 32253-32257. http://dx.doi.org/10.1074/jbc.M204410200.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 32253-32257
-
-
Miura, S.1
Gan, J.W.2
Brzostowski, J.3
Parisi, M.J.4
Schultz, C.J.5
Londos, C.6
Oliver, B.7
Kimmel, A.R.8
-
22
-
-
36649015243
-
Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis
-
Brasaemle DL. 2007. Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis. J. Lipid Res. 48:2547-2559. http://dx.doi.org/10.1194/jlr.R700014-JLR200.
-
(2007)
J. Lipid Res
, vol.48
, pp. 2547-2559
-
-
Brasaemle, D.L.1
-
23
-
-
14344268795
-
Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity
-
Tansey JT, Sztalryd C, Gruia-Gray J, Roush DL, Zee JV, Gavrilova O, Reitman ML, Deng CX, Li C, Kimmel AR, Londos C. 2001. Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity. Proc. Natl. Acad. Sci. U. S. A. 98:6494-6499. http://dx.doi.org/10.1073/pnas.101042998.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A
, vol.98
, pp. 6494-6499
-
-
Tansey, J.T.1
Sztalryd, C.2
Gruia-Gray, J.3
Roush, D.L.4
Zee, J.V.5
Gavrilova, O.6
Reitman, M.L.7
Deng, C.X.8
Li, C.9
Kimmel, A.R.10
Londos, C.11
-
24
-
-
0037477829
-
Perilipin A is essential for the translocation of hormonesensitive lipase during lipolytic activation
-
Sztalryd C, Xu G, Dorward H, Tansey JT, Contreras JA, Kimmel AR, Londos C. 2003. Perilipin A is essential for the translocation of hormonesensitive lipase during lipolytic activation. J. Cell Biol. 161:1093-1103. http://dx.doi.org/10.1083/jcb.200210169.
-
(2003)
J. Cell Biol
, vol.161
, pp. 1093-1103
-
-
Sztalryd, C.1
Xu, G.2
Dorward, H.3
Tansey, J.T.4
Contreras, J.A.5
Kimmel, A.R.6
Londos, C.7
-
25
-
-
4744341229
-
Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytes
-
Subramanian V, Rothenberg A, Gomez C, Cohen AW, Garcia A, Bhattacharyya S, Shapiro L, Dolios G, Wang R, Lisanti MP, Brasaemle DL. 2004. Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytes. J. Biol. Chem. 279:42062-42071. http://dx.doi.org/10.1074/jbc.M407462200.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 42062-42071
-
-
Subramanian, V.1
Rothenberg, A.2
Gomez, C.3
Cohen, A.W.4
Garcia, A.5
Bhattacharyya, S.6
Shapiro, L.7
Dolios, G.8
Wang, R.9
Lisanti, M.P.10
Brasaemle, D.L.11
-
26
-
-
33646128723
-
Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman syndrome
-
Lass A, Zimmermann R, Haemmerle G, Riederer M, Schoiswohl G, Schweiger M, Kienesberger P, Strauss JG, Gorkiewicz G, Zechner R. 2006. Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman syndrome. Cell Metab. 3:309-319. http://dx.doi.org/10.1016/j.cmet.2006.03.005.
-
(2006)
Cell Metab
, vol.3
, pp. 309-319
-
-
Lass, A.1
Zimmermann, R.2
Haemmerle, G.3
Riederer, M.4
Schoiswohl, G.5
Schweiger, M.6
Kienesberger, P.7
Strauss, J.G.8
Gorkiewicz, G.9
Zechner, R.10
-
27
-
-
3142738035
-
CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome
-
Yamaguchi T, Omatsu N, Matsushita S, Osumi T. 2004. CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome. J. Biol. Chem. 279:30490-30497. http://dx.doi.org/10.1074/jbc.M403920200.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 30490-30497
-
-
Yamaguchi, T.1
Omatsu, N.2
Matsushita, S.3
Osumi, T.4
-
28
-
-
71749098785
-
Perilipin controls lipolysis by regulating the interactions of AB-hydrolase containing 5 (Abhd5) and adipose triglyceride lipase (Atgl)
-
Granneman JG, Moore HP, Krishnamoorthy R, Rathod M. 2009. Perilipin controls lipolysis by regulating the interactions of AB-hydrolase containing 5 (Abhd5) and adipose triglyceride lipase (Atgl). J. Biol. Chem. 284:34538-34544. http://dx.doi.org/10.1074/jbc.M109.068478.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 34538-34544
-
-
Granneman, J.G.1
Moore, H.P.2
Krishnamoorthy, R.3
Rathod, M.4
-
29
-
-
33847714769
-
Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes
-
Miyoshi H, Perfield JW, II, Souza SC, Shen WJ, Zhang HH, Stancheva ZS, Kraemer FB, Obin MS, Greenberg AS. 2007. Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes. J. Biol. Chem. 282: 996-1002. http://dx.doi.org/10.1074/jbc.M605770200.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 996-1002
-
-
Miyoshi, H.1
Perfield II, J.W.2
Souza, S.C.3
Shen, W.J.4
Zhang, H.H.5
Stancheva, Z.S.6
Kraemer, F.B.7
Obin, M.S.8
Greenberg, A.S.9
-
30
-
-
29044440372
-
Signalling mechanisms regulating lipolysis
-
Carmen GY, Victor SM. 2006. Signalling mechanisms regulating lipolysis. Cell. Signal. 18:401-408. http://dx.doi.org/10.1016/j.cellsig.2005.08.009.
-
(2006)
Cell. Signal
, vol.18
, pp. 401-408
-
-
Carmen, G.Y.1
Victor, S.M.2
-
31
-
-
76049091112
-
Lipid homeostasis, lipotoxicity and the metabolic syndrome
-
Unger RH, Clark GO, Scherer PE, Orci L. 2010. Lipid homeostasis, lipotoxicity and the metabolic syndrome. Biochim. Biophys. Acta 1801: 209-214. http://dx.doi.org/10.1016/j.bbalip.2009.10.006.
-
(2010)
Biochim. Biophys. Acta
, vol.1801
, pp. 209-214
-
-
Unger, R.H.1
Clark, G.O.2
Scherer, P.E.3
Orci, L.4
-
32
-
-
58149339613
-
Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival
-
Narbonne P, Roy R. 2009. Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival. Nature 457: 210-214. http://dx.doi.org/10.1038/nature07536.
-
(2009)
Nature
, vol.457
, pp. 210-214
-
-
Narbonne, P.1
Roy, R.2
-
33
-
-
55849101681
-
Fat metabolism links germline stem cells and longevity in C
-
Wang MC, O'Rourke EJ, Ruvkun G. 2008. Fat metabolism links germline stem cells and longevity in C. elegans. Science 322:957-960. http://dx.doi.org/10.1126/science.1162011.
-
(2008)
elegans. Science
, vol.322
, pp. 957-960
-
-
Wang, M.C.1
O'Rourke, E.J.2
Ruvkun, G.3
-
34
-
-
84874271499
-
w-6 polyunsaturated fatty acids extend life span through the activation of autophagy
-
O'Rourke EJ, Kuballa P, Xavier R, Ruvkun G. 2013. w-6 polyunsaturated fatty acids extend life span through the activation of autophagy. Genes Dev. 27:429-440. http://dx.doi.org/10.1101/gad.205294.112.
-
(2013)
Genes Dev
, vol.27
, pp. 429-440
-
-
O'Rourke, E.J.1
Kuballa, P.2
Xavier, R.3
Ruvkun, G.4
-
35
-
-
84878533962
-
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
-
O'Rourke EJ, Ruvkun G. 2013. MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability. Nat. Cell Biol. 15: 668-676. http://dx.doi.org/10.1038/ncb2741.
-
(2013)
Nat. Cell Biol
, vol.15
, pp. 668-676
-
-
O'Rourke, E.J.1
Ruvkun, G.2
-
36
-
-
65349113758
-
IRE-1 and HSP-4 contribute to energy homeostasis via fasting-induced lipases in C
-
Jo H, Shim J, Lee JH, Lee J, Kim JB. 2009. IRE-1 and HSP-4 contribute to energy homeostasis via fasting-induced lipases in C. elegans. Cell Metab. 9:440-448. http://dx.doi.org/10.1016/j.cmet.2009.04.004.
-
(2009)
elegans. Cell Metab
, vol.9
, pp. 440-448
-
-
Jo, H.1
Shim, J.2
Lee, J.H.3
Lee, J.4
Kim, J.B.5
-
37
-
-
70350365111
-
C. elegans major fats are stored in vesicles distinct from lysosome-related organelles
-
O'Rourke EJ, Soukas AA, Carr CE, Ruvkun G. 2009. C. elegans major fats are stored in vesicles distinct from lysosome-related organelles. Cell Metab. 10:430-435. http://dx.doi.org/10.1016/j.cmet.2009.10.002.
-
(2009)
Cell Metab
, vol.10
, pp. 430-435
-
-
O'Rourke, E.J.1
Soukas, A.A.2
Carr, C.E.3
Ruvkun, G.4
-
38
-
-
70849108761
-
Statins inhibit protein lipidation and induce the unfolded protein response in the non-sterol producing nematode Caenorhabditis elegans
-
Mörck C, Olsen L, Kurth C, Persson A, Storm NJ, Svensson E, Jansson JO, Hellqvist M, Enejder A, Faergeman NJ, Pilon M. 2009. Statins inhibit protein lipidation and induce the unfolded protein response in the non-sterol producing nematode Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A. 106:18285-18290. http://dx.doi.org/10.1073/pnas.0907117106.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A
, vol.106
, pp. 18285-18290
-
-
Mörck, C.1
Olsen, L.2
Kurth, C.3
Persson, A.4
Storm, N.J.5
Svensson, E.6
Jansson, J.O.7
Hellqvist, M.8
Enejder, A.9
Faergeman, N.J.10
Pilon, M.11
-
39
-
-
70449560405
-
The influence of bacterial diet on fat storage in C
-
Brooks KK, Liang B, Watts JL. 2009. The influence of bacterial diet on fat storage in C. elegans. PLoS One 4:e7545. http://dx.doi.org/10.1371/journal.pone.0007545.
-
(2009)
elegans. PLoS One
, vol.4
, pp. e7545
-
-
Brooks, K.K.1
Liang, B.2
Watts, J.L.3
-
40
-
-
61449244533
-
Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans
-
Soukas AA, Kane EA, Carr CE, Melo JA, Ruvkun G. 2009. Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans. Genes Dev. 23:496-511. http://dx.doi.org/10.1101/gad.1775409.
-
(2009)
Genes Dev
, vol.23
, pp. 496-511
-
-
Soukas, A.A.1
Kane, E.A.2
Carr, C.E.3
Melo, J.A.4
Ruvkun, G.5
-
41
-
-
0038005018
-
DAVID: Database for Annotation, Visualization, and Integrated Discovery
-
Dennis G, Jr, Sherman BT, Hosack DA, Yang J, Gao W, Lane HC, Lempicki RA. 2003. DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol. 4:P3. http://dx.doi.org/10.1186/gb-2003-4-5-p3.
-
(2003)
Genome Biol
, vol.4
, pp. P3
-
-
Dennis Jr., G.1
Sherman, B.T.2
Hosack, D.A.3
Yang, J.4
Gao, W.5
Lane, H.C.6
Lempicki, R.A.7
-
42
-
-
33745612095
-
Pvclust: an R package for assessing the uncertainty in hierarchical clustering
-
Suzuki R, Shimodaira H. 2006. Pvclust: an R package for assessing the uncertainty in hierarchical clustering. Bioinformatics 22:1540-1542. http://dx.doi.org/10.1093/bioinformatics/btl117.
-
(2006)
Bioinformatics
, vol.22
, pp. 1540-1542
-
-
Suzuki, R.1
Shimodaira, H.2
-
43
-
-
34548755067
-
Assay of protein kinases using radiolabeled ATP: a protocol
-
Hastie CJ, McLauchlan HJ, Cohen P. 2006. Assay of protein kinases using radiolabeled ATP: a protocol. Nat. Protoc. 1:968-971. http://dx.doi.org/10.1038/nprot.2006.149.
-
(2006)
Nat. Protoc
, vol.1
, pp. 968-971
-
-
Hastie, C.J.1
McLauchlan, H.J.2
Cohen, P.3
-
44
-
-
84905040517
-
Comparative gene identification 58/alpha/beta hydrolase domain 5 lacks lysophosphatidic acid acyltransferase activity
-
McMahon D, Dinh A, Kurz D, Shah D, Han GS, Carman GM, Brasaemle DL. 2014. Comparative gene identification 58/alpha/beta hydrolase domain 5 lacks lysophosphatidic acid acyltransferase activity. J. Lipid Res. 55:1750-1761. http://dx.doi.org/10.1194/jlr.M051151.
-
(2014)
J. Lipid Res
, vol.55
, pp. 1750-1761
-
-
McMahon, D.1
Dinh, A.2
Kurz, D.3
Shah, D.4
Han, G.S.5
Carman, G.M.6
Brasaemle, D.L.7
-
45
-
-
33845261493
-
A rapid method of total lipid extraction and purification
-
Bligh EG, Dyer WJ. 1959. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37:911-917. http://dx.doi.org/10.1139/o59-099.
-
(1959)
Can. J. Biochem. Physiol
, vol.37
, pp. 911-917
-
-
Bligh, E.G.1
Dyer, W.J.2
-
46
-
-
77949524057
-
Genetic and dietary regulation of lipid droplet expansion in Caenorhabditis elegans
-
Zhang SO, Box AC, Xu N, Le Men J, Yu J, Guo F, Trimble R, Mak HY. 2010. Genetic and dietary regulation of lipid droplet expansion in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A. 107:4640-4645. http://dx.doi.org/10.1073/pnas.0912308107.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A
, vol.107
, pp. 4640-4645
-
-
Zhang, S.O.1
Box, A.C.2
Xu, N.3
Le Men, J.4
Yu, J.5
Guo, F.6
Trimble, R.7
Mak, H.Y.8
-
47
-
-
84864818294
-
Proteomic study and marker protein identification of Caenorhabditis elegans lipid droplets
-
Zhang P, Na H, Liu Z, Zhang S, Xue P, Chen Y, Pu J, Peng G, Huang X, Yang F, Xie Z, Xu T, Xu P, Ou G, Zhang SO, Liu P. 2012. Proteomic study and marker protein identification of Caenorhabditis elegans lipid droplets. Mol. Cell. Proteomics 11:317-328. http://dx.doi.org/10.1074/mcp.M111.016345.
-
(2012)
Mol. Cell. Proteomics
, vol.11
, pp. 317-328
-
-
Zhang, P.1
Na, H.2
Liu, Z.3
Zhang, S.4
Xue, P.5
Chen, Y.6
Pu, J.7
Peng, G.8
Huang, X.9
Yang, F.10
Xie, Z.11
Xu, T.12
Xu, P.13
Ou, G.14
Zhang, S.O.15
Liu, P.16
-
48
-
-
0034764272
-
Mutations in CGI-58, the gene encoding a new protein of the esterase/lipase/thioesterase subfamily, in Chanarin-Dorfman syndrome
-
Lefèvre C, Jobard F, Caux F, Bouadjar B, Karaduman A, Heilig R, Lakhdar H, Wollenberg A, Verret JL, Weissenbach J, Ozguc M, Lathrop M, Prud'homme JF, Fischer J. 2001. Mutations in CGI-58, the gene encoding a new protein of the esterase/lipase/thioesterase subfamily, in Chanarin-Dorfman syndrome. Am. J. Hum. Genet. 69:1002-1012. http://dx.doi.org/10.1086/324121.
-
(2001)
Am. J. Hum. Genet
, vol.69
, pp. 1002-1012
-
-
Lefèvre, C.1
Jobard, F.2
Caux, F.3
Bouadjar, B.4
Karaduman, A.5
Heilig, R.6
Lakhdar, H.7
Wollenberg, A.8
Verret, J.L.9
Weissenbach, J.10
Ozguc, M.11
Lathrop, M.12
Prud'homme, J.F.13
Fischer, J.14
-
49
-
-
54049155777
-
CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid
-
Ghosh AK, Ramakrishnan G, Chandramohan C, Rajasekharan R. 2008. CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid. J. Biol. Chem. 283:24525-24533. http://dx.doi.org/10.1074/jbc.M801783200.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 24525-24533
-
-
Ghosh, A.K.1
Ramakrishnan, G.2
Chandramohan, C.3
Rajasekharan, R.4
-
50
-
-
77950609928
-
CGI-58/ABHD5 is a coenzyme A-dependent lysophosphatidic acid acyltransferase
-
Montero-Moran G, Caviglia JM, McMahon D, Rothenberg A, Subramanian V, Xu Z, Lara-Gonzalez S, Storch J, Carman GM, Brasaemle DL. 2010. CGI-58/ABHD5 is a coenzyme A-dependent lysophosphatidic acid acyltransferase. J. Lipid Res. 51:709-719. http://dx.doi.org/10.1194/jlr.M001917.
-
(2010)
J. Lipid Res
, vol.51
, pp. 709-719
-
-
Montero-Moran, G.1
Caviglia, J.M.2
McMahon, D.3
Rothenberg, A.4
Subramanian, V.5
Xu, Z.6
Lara-Gonzalez, S.7
Storch, J.8
Carman, G.M.9
Brasaemle, D.L.10
-
51
-
-
0025131925
-
Characterization of Escherichia coli cells deficient in 1-acyl-sn-glycerol-3-phosphate acyltransferase activity
-
Coleman J. 1990. Characterization of Escherichia coli cells deficient in 1-acyl-sn-glycerol-3-phosphate acyltransferase activity. J. Biol. Chem. 265:17215-17221.
-
(1990)
J. Biol. Chem
, vol.265
, pp. 17215-17221
-
-
Coleman, J.1
-
52
-
-
84858782079
-
AMPK: a nutrient and energy sensor that maintains energy homeostasis
-
Hardie DG, Ross FA, Hawley SA. 2012. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat. Rev. Mol. Cell Biol. 13: 251-262. http://dx.doi.org/10.1038/nrm3311.
-
(2012)
Nat. Rev. Mol. Cell Biol
, vol.13
, pp. 251-262
-
-
Hardie, D.G.1
Ross, F.A.2
Hawley, S.A.3
-
53
-
-
47249157348
-
The Caenorhabditis elegans AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and is required for resistance to oxidative stress and for normal motility and foraging behavior
-
Lee H, Cho JS, Lambacher N, Lee J, Lee SJ, Lee TH, Gartner A, Koo HS. 2008. The Caenorhabditis elegans AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and is required for resistance to oxidative stress and for normal motility and foraging behavior. J. Biol. Chem. 283:14988-14993 http://dx.doi.org/10.1074/jbc.M709115200.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 14988-14993
-
-
Lee, H.1
Cho, J.S.2
Lambacher, N.3
Lee, J.4
Lee, S.J.5
Lee, T.H.6
Gartner, A.7
Koo, H.S.8
-
54
-
-
15544390526
-
Mutations that rescue the paralysis of Caenorhabditis elegans ric-8 (synembryn) mutants activate the G alpha(s) pathway and define a third major branch of the synaptic signaling network
-
Schade MA, Reynolds NK, Dollins CM, Miller KG. 2005. Mutations that rescue the paralysis of Caenorhabditis elegans ric-8 (synembryn) mutants activate the G alpha(s) pathway and define a third major branch of the synaptic signaling network. Genetics 169:631-649. http://dx.doi.org/10.1534/genetics.104.032334.
-
(2005)
Genetics
, vol.169
, pp. 631-649
-
-
Schade, M.A.1
Reynolds, N.K.2
Dollins, C.M.3
Miller, K.G.4
-
55
-
-
84865420340
-
Identification and functional characterization of protein kinase A phosphorylation sites in the major lipolytic protein, adipose triglyceride lipase
-
Pagnon J, Matzaris M, Stark R, Meex RC, Macaulay SL, Brown W, O'Brien PE, Tiganis T, Watt MJ. 2012. Identification and functional characterization of protein kinase A phosphorylation sites in the major lipolytic protein, adipose triglyceride lipase. Endocrinology 153:4278-4289. http://dx.doi.org/10.1210/en.2012-1127.
-
(2012)
Endocrinology
, vol.153
, pp. 4278-4289
-
-
Pagnon, J.1
Matzaris, M.2
Stark, R.3
Meex, R.C.4
Macaulay, S.L.5
Brown, W.6
O'Brien, P.E.7
Tiganis, T.8
Watt, M.J.9
-
56
-
-
8844226709
-
Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase
-
Zimmermann R, Strauss JG, Haemmerle G, Schoiswohl G, Birner-Gruenberger R, Riederer M, Lass A, Neuberger G, Eisenhaber F, Hermetter A, Zechner R. 2004. Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Science 306:1383-1386. http://dx.doi.org/10.1126/science.1100747.
-
(2004)
Science
, vol.306
, pp. 1383-1386
-
-
Zimmermann, R.1
Strauss, J.G.2
Haemmerle, G.3
Schoiswohl, G.4
Birner-Gruenberger, R.5
Riederer, M.6
Lass, A.7
Neuberger, G.8
Eisenhaber, F.9
Hermetter, A.10
Zechner, R.11
-
57
-
-
33646462136
-
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase
-
Haemmerle G, Lass A, Zimmermann R, Gorkiewicz G, Meyer C, Rozman J, Heldmaier G, Maier R, Theussl C, Eder S, Kratky D, Wagner EF, Klingenspor M, Hoefler G, Zechner R. 2006. Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science 312:734-737. http://dx.doi.org/10.1126/science.1123965.
-
(2006)
Science
, vol.312
, pp. 734-737
-
-
Haemmerle, G.1
Lass, A.2
Zimmermann, R.3
Gorkiewicz, G.4
Meyer, C.5
Rozman, J.6
Heldmaier, G.7
Maier, R.8
Theussl, C.9
Eder, S.10
Kratky, D.11
Wagner, E.F.12
Klingenspor, M.13
Hoefler, G.14
Zechner, R.15
-
58
-
-
77951212321
-
Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58)
-
Radner FP, Streith IE, Schoiswohl G, Schweiger M, Kumari M, Eichmann TO, Rechberger G, Koefeler HC, Eder S, Schauer S, Theussl HC, Preiss-Landl K, Lass A, Zimmermann R, Hoefler G, Zechner R, Haemmerle G. 2010. Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58). J. Biol. Chem. 285:7300-7311. http://dx.doi.org/10.1074/jbc.M109.081877.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 7300-7311
-
-
Radner, F.P.1
Streith, I.E.2
Schoiswohl, G.3
Schweiger, M.4
Kumari, M.5
Eichmann, T.O.6
Rechberger, G.7
Koefeler, H.C.8
Eder, S.9
Schauer, S.10
Theussl, H.C.11
Preiss-Landl, K.12
Lass, A.13
Zimmermann, R.14
Hoefler, G.15
Zechner, R.16
Haemmerle, G.17
-
59
-
-
84866382121
-
The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface
-
Xu N, Zhang SO, Cole RA, McKinney SA, Guo F, Haas JT, Bobba S, Farese RV, Jr, Mak HY. 2012. The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface. J. Cell Biol. 198: 895-911. http://dx.doi.org/10.1083/jcb.201201139.
-
(2012)
J. Cell Biol
, vol.198
, pp. 895-911
-
-
Xu, N.1
Zhang, S.O.2
Cole, R.A.3
McKinney, S.A.4
Guo, F.5
Haas, J.T.6
Bobba, S.7
Farese Jr., R.V.8
Mak, H.Y.9
-
60
-
-
0033671833
-
Absence of perilipin results in leanness and reverses obesity in Lepr(db/db) mice
-
Martinez-Botas J, Anderson JB, Tessier D, Lapillonne A, Chang BH, Quast MJ, Gorenstein D, Chen KH, Chan L. 2000. Absence of perilipin results in leanness and reverses obesity in Lepr(db/db) mice. Nat. Genet. 26:474-479. http://dx.doi.org/10.1038/82630.
-
(2000)
Nat. Genet
, vol.26
, pp. 474-479
-
-
Martinez-Botas, J.1
Anderson, J.B.2
Tessier, D.3
Lapillonne, A.4
Chang, B.H.5
Quast, M.J.6
Gorenstein, D.7
Chen, K.H.8
Chan, L.9
-
61
-
-
26944489689
-
Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila
-
Grönke S, Mildner A, Fellert S, Tennagels N, Petry S, Muller G, Jackle H, Kuhnlein RP. 2005. Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila. Cell Metab. 1:323-330. http://dx.doi.org/10.1016/j.cmet.2005.04.003.
-
(2005)
Cell Metab
, vol.1
, pp. 323-330
-
-
Grönke, S.1
Mildner, A.2
Fellert, S.3
Tennagels, N.4
Petry, S.5
Muller, G.6
Jackle, H.7
Kuhnlein, R.P.8
-
62
-
-
27444433258
-
Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members
-
Lake AC, Sun Y, Li JL, Kim JE, Johnson JW, Li D, Revett T, Shih HH, Liu W, Paulsen JE, Gimeno RE. 2005. Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members. J. Lipid Res. 46:2477-2487. http://dx.doi.org/10.1194/jlr.M500290-JLR200.
-
(2005)
J. Lipid Res
, vol.46
, pp. 2477-2487
-
-
Lake, A.C.1
Sun, Y.2
Li, J.L.3
Kim, J.E.4
Johnson, J.W.5
Li, D.6
Revett, T.7
Shih, H.H.8
Liu, W.9
Paulsen, J.E.10
Gimeno, R.E.11
-
63
-
-
33644764922
-
Adipose triglyceride lipase: function, regulation by insulin, and comparison with adiponutrin
-
Kershaw EE, Hamm JK, Verhagen LA, Peroni O, Katic M, Flier JS. 2006. Adipose triglyceride lipase: function, regulation by insulin, and comparison with adiponutrin. Diabetes 55:148-157. http://dx.doi.org/10.2337/diabetes.55.01.06.db05-0982.
-
(2006)
Diabetes
, vol.55
, pp. 148-157
-
-
Kershaw, E.E.1
Hamm, J.K.2
Verhagen, L.A.3
Peroni, O.4
Katic, M.5
Flier, J.S.6
-
64
-
-
8744297386
-
Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis
-
Villena JA, Roy S, Sarkadi-Nagy E, Kim KH, Sul HS. 2004. Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis. J. Biol. Chem. 279:47066-47075. http://dx.doi.org/10.1074/jbc.M403855200.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 47066-47075
-
-
Villena, J.A.1
Roy, S.2
Sarkadi-Nagy, E.3
Kim, K.H.4
Sul, H.S.5
-
65
-
-
58149308056
-
Cdk1/Cdc28-dependent activation of the major triacylglycerol lipase Tgl4 in yeast links lipolysis to cell-cycle progression
-
Kurat CF, Wolinski H, Petschnigg J, Kaluarachchi S, Andrews B, Natter K, Kohlwein SD. 2009. Cdk1/Cdc28-dependent activation of the major triacylglycerol lipase Tgl4 in yeast links lipolysis to cell-cycle progression. Mol. Cell 33:53-63. http://dx.doi.org/10.1016/j.molcel.2008.12.019.
-
(2009)
Mol. Cell
, vol.33
, pp. 53-63
-
-
Kurat, C.F.1
Wolinski, H.2
Petschnigg, J.3
Kaluarachchi, S.4
Andrews, B.5
Natter, K.6
Kohlwein, S.D.7
-
66
-
-
0026783771
-
Mechanism of hormone-stimulated lipolysis in adipocytes: translocation of hormone-sensitive lipase to the lipid storage droplet
-
Egan JJ, Greenberg AS, Chang MK, Wek SA, Moos MC, Jr, Londos C. 1992. Mechanism of hormone-stimulated lipolysis in adipocytes: translocation of hormone-sensitive lipase to the lipid storage droplet. Proc. Natl. Acad. Sci. U. S. A. 89:8537-8541. http://dx.doi.org/10.1073/pnas.89.18.8537.
-
(1992)
Proc. Natl. Acad. Sci. U. S. A
, vol.89
, pp. 8537-8541
-
-
Egan, J.J.1
Greenberg, A.S.2
Chang, M.K.3
Wek, S.A.4
Moos Jr., M.C.5
Londos, C.6
-
67
-
-
84881261968
-
Dual regulation of adipose triglyceride lipase by pigment epithelium-derived factor: a novel mechanistic insight into progressive obesity
-
Dai Z, Qi W, Li C, Lu J, Mao Y, Yao Y, Li L, Zhang T, Hong H, Li S, Zhou T, Yang Z, Yang X, Gao G, Cai W. 2013. Dual regulation of adipose triglyceride lipase by pigment epithelium-derived factor: a novel mechanistic insight into progressive obesity. Mol. Cell. Endocrinol. 377:123-134. http://dx.doi.org/10.1016/j.mce.2013.07.001.
-
(2013)
Mol. Cell. Endocrinol
, vol.377
, pp. 123-134
-
-
Dai, Z.1
Qi, W.2
Li, C.3
Lu, J.4
Mao, Y.5
Yao, Y.6
Li, L.7
Zhang, T.8
Hong, H.9
Li, S.10
Zhou, T.11
Yang, Z.12
Yang, X.13
Gao, G.14
Cai, W.15
-
68
-
-
84872840929
-
Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover
-
Olzmann JA, Richter CM, Kopito RR. 2013. Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover. Proc. Natl. Acad. Sci. U. S. A. 110:1345-1350. http://dx.doi.org/10.1073/pnas.1213738110.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A
, vol.110
, pp. 1345-1350
-
-
Olzmann, J.A.1
Richter, C.M.2
Kopito, R.R.3
-
69
-
-
84887449305
-
An integrated serotonin and octopamine neuronal circuit directs the release of an endocrine signal to control C
-
Noble T, Stieglitz J, Srinivasan S. 2013. An integrated serotonin and octopamine neuronal circuit directs the release of an endocrine signal to control C. elegans body fat. Cell Metab. 18:672-684. http://dx.doi.org/10.1016/j.cmet.2013.09.007.
-
(2013)
elegans body fat. Cell Metab
, vol.18
, pp. 672-684
-
-
Noble, T.1
Stieglitz, J.2
Srinivasan, S.3
-
70
-
-
80052756899
-
Insulin/IGF-1 receptor signaling enhances biosynthetic activity and fat mobilization in the initial phase of starvation in adult male C
-
Tan KT, Luo SC, Ho WZ, Lee YH. 2011. Insulin/IGF-1 receptor signaling enhances biosynthetic activity and fat mobilization in the initial phase of starvation in adult male C. elegans. Cell Metab. 14:390-402. http://dx.doi.org/10.1016/j.cmet.2011.06.019.
-
(2011)
elegans. Cell Metab
, vol.14
, pp. 390-402
-
-
Tan, K.T.1
Luo, S.C.2
Ho, W.Z.3
Lee, Y.H.4
-
71
-
-
47749085114
-
AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance
-
Gauthier MS, Miyoshi H, Souza SC, Cacicedo JM, Saha AK, Greenberg AS, Ruderman NB. 2008. AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance. J. Biol. Chem. 283:16514-16524. http://dx.doi.org/10.1074/jbc.M708177200.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 16514-16524
-
-
Gauthier, M.S.1
Miyoshi, H.2
Souza, S.C.3
Cacicedo, J.M.4
Saha, A.K.5
Greenberg, A.S.6
Ruderman, N.B.7
-
72
-
-
75049085233
-
PKA phosphor ylates and inactivates AMPKalpha to promote efficient lipolysis
-
Djouder N, Tuerk RD, Suter M, Salvioni P, Thali RF, Scholz R, Vaahtomeri K, Auchli Y, Rechsteiner H, Brunisholz RA, Viollet B, Makela TP, Wallimann T, Neumann D, Krek W. 2010. PKA phosphor ylates and inactivates AMPKalpha to promote efficient lipolysis. EMBO J. 29:469-481. http://dx.doi.org/10.1038/emboj.2009.339.
-
(2010)
EMBO J
, vol.29
, pp. 469-481
-
-
Djouder, N.1
Tuerk, R.D.2
Suter, M.3
Salvioni, P.4
Thali, R.F.5
Scholz, R.6
Vaahtomeri, K.7
Auchli, Y.8
Rechsteiner, H.9
Brunisholz, R.A.10
Viollet, B.11
Makela, T.P.12
Wallimann, T.13
Neumann, D.14
Krek, W.15
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