Proteomic study and marker protein identification of Caenorhabditis elegans lipid droplets

Molecular and Cellular Proteomics

Volumn 11, Issue 8, 2012, Pages 317-328

  Zhang, Peng ^a,b   Na, Huimin ^a,b   Liu, Zhenglong ^c   Zhang, Shuyan ^a   Xue, Peng ^a   Chen, Yong ^a   Pu, Jing ^a,b   Peng, Gong ^a,b   Huang, Xun ^c   Yang, Fuquan ^a   Xie, Zhensheng ^a   Xu, Tao ^a   Xu, Pingyong ^a   Ou, Guangshuo ^a   Zhang, Shaobing O ^d   Liu, Pingsheng ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

^d CAPITAL NORMAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

FAT DROPLET; OXIDOREDUCTASE;

ARTICLE; CAENORHABDITIS ELEGANS; CHEMICAL ANALYSIS; ENZYME LOCALIZATION; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS;

ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; BUTYRYL-COA DEHYDROGENASE; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CYTOPLASMIC VESICLES; LIPID METABOLISM; LIPIDS; MASS SPECTROMETRY; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; PROTEOME; PROTEOMICS;

CAENORHABDITIS ELEGANS; MAMMALIA;

EID: 84864818294     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M111.016345     Document Type: Article

References (46)

1. Murphy, D. J. (2001) The biogenesis and functions of lipid bodies in animals, plants and microorganisms. Progress Lipid Res. 40, 325-438
2. Martin, S., and Parton, R. G. (2006) Lipid droplets: a unified view of a dynamic organelle. Mol. Cell Biol. 7, 373-378
3. Farese, R. V., Jr., and Walther, T. C. (2009) Lipid droplets finally get a little R-E-S-P-E-C-T. Cell 139, 855-860
4. Goodman, J. M. (2009) Demonstrated and inferred metabolism associated with cytosolic lipid droplets. J. Lipid Res. 50, 2148-2156
5. Zehmer, J. K., Huang, Y., Peng, G., Pu, J., Anderson, R. G., and Liu, P. (2009) A role for lipid droplets in inter-membrane lipid traffic. Proteomics 9, 914-921
6. Liu, P., Bartz, R., Zehmer, J. K., Ying, Y. S., Zhu, M., Serrero, G., and Anderson, R. G. (2007) Rab-regulated interaction of early endosomes with lipid droplets. Biochim. Biophys. Acta 1773, 784-793
7. Liu, P., Bartz, R., Zehmer, J. K., Ying, Y., and Anderson, R. G. (2008) Rab-regulated membrane traffic between adiposomes and multiple endomembrane systems. Methods Enzymol. 439, 327-337
8. Szymanski, K. M., Binns, D., Bartz, R., Grishin, N. V., Li, W. P., Agarwal, A. K., Garg, A., Anderson, R. G., and Goodman, J. M. (2007) The lipodystrophy protein seipin is found at endoplasmic reticulum lipid droplet junctions and is important for droplet morphology. Proc. Natl. Acad. Sci. U. S. A. 104, 20890-20895
9. Kimmel, A. R., Brasaemle, D. L., McAndrews-Hill, M., Sztalryd, C., and Londos, C. (2010) Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins. J. Lipid Res. 51, 468-471
10. Athenstaedt, K., Zweytick, D., Jandrositz, A., Kohlwein, S. D., and Daum, G. (1999) Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J. Bacteriol. 181, 6441-6448
11. Wu, C. C., Howell, K. E., Neville, M. C., Yates, J. R., 3rd, and McManaman, J. L. (2000) Proteomics reveal a link between the endoplasmic reticulum and lipid secretory mechanisms in mammary epithelial cells. Electrophoresis 21, 3470-3482
12. Liu, P., Ying, Y., Zhao, Y., Mundy, D. I., Zhu, M., and Anderson, R. G. (2004) Chinese hamster ovary K2 cell lipid droplets appear to be metabolic organelles involved in membrane traffic. J. Biol. Chem. 279, 3787-3792
13. Brasaemle, D. L., Dolios, G., Shapiro, L., and Wang, R. (2004) Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes. J. Biol. Chem. 279, 46835-46842
14. Fujimoto, Y., Itabe, H., Sakai, J., Makita, M., Noda, J., Mori, M., Higashi, Y., Kojima, S., and Takano, T. (2004) Identification of major proteins in the lipid droplet-enriched fraction isolated from the human hepatocyte cell line HuH7. Biochim. Biophys. Acta 1644, 47-59
15. Umlauf, E., Csaszar, E., Moertelmaier, M., Schuetz, G. J., Parton, R. G., and Prohaska, R. (2004) Association of stomatin with lipid bodies. J. Biol. Chem. 279, 23699-23709
16. Bartz, R., Zehmer, J. K., Zhu, M., Chen, Y., Serrero, G., Zhao, Y., and Liu, P. (2007) Dynamic activity of lipid droplets: protein phosphorylation and GTP-mediated protein translocation. J. Proteome Res. 6, 3256-3265
17. Bartz, R., Li, W. H., Venables, B., Zehmer, J. K., Roth, M. R., Welti, R., Anderson, R. G., Liu, P., and Chapman, K. D. (2007) Lipidomics reveals that adiposomes store ether lipids and mediate phospholipid traffic. J. Lipid Res. 48, 837-847
18. Beller, M., Riedel, D., Jänsch, L., Dieterich, G., Wehland, J., Jackle, H., and Kühnlein, R. P. (2006) Characterization of the Drosophila lipid droplet subproteome. Mol. Cell. Proteomics 5, 1082-1094
19. Cermelli, S., Guo, Y., Gross, S. P., and Welte, M. A. (2006) The lipid-droplet proteome reveals that droplets are a protein-storage depot. Current Biol. 16, 1783-1795
20. Zhang, S., Du, Y., Wang, Y., and Liu, P. (2010) Lipid Droplet - A Cellular Organelle for Lipid Metabolism. Acta Biophys. Sin. 26, 97-105
21. Zhang, S. O., Box, A. C., Xu, N., Le Men, J., Yu, J., Guo, F., Trimble, R., and Mak, H. Y. (2010) Genetic and dietary regulation of lipid droplet expansion in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A. 107, 4640-4645
22. Zhang, S. O., Trimble, R., Guo, F., and Mak, H. Y. (2010) Lipid droplets as ubiquitous fat storage organelles in C. elegans. BMC Cell Biol. 11, 96
23. Schroeder, L. K., Kremer, S., Kramer, M. J., Currie, E., Kwan, E., Watts, J. L., Lawrenson, A. L., and Hermann, G. J. (2007) Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle. Mol. Biol. Cell 18, 995-1008
24. Brooks, K. K., Liang, B., and Watts, J. L. (2009) The influence of bacterial diet on fat storage in C. elegans. PloS One 4, e7545
25. O'Rourke, E. J., Soukas, A. A., Carr, C. E., and Ruvkun, G. (2009) C. elegans major fats are stored in vesicles distinct from lysosome-related organelles. Cell Metabolism 10, 430-435
26. Suzuki, M., Shinohara, Y., Ohsaki, Y., and Fujimoto, T. (2011) Lipid droplets: size matters. J. Elect. Micros. 60, S101-116
27. Brasaemle, D. L., and Wolins, N. E. (2012) Packaging of fat: an evolving model of lipid droplet assembly and expansion. J. Biol. Chem. 287, 2273-2279
28. Szklarczyk, D., Franceschini, A., Kuhn, M., Simonovic, M., Roth, A., Minguez, P., Doerks, T., Stark, M., Muller, J., Bork, P., Jensen, L. J., and von Mering, C. (2011) The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored. Nucleic Acids Res. 39, D561-568
29. Narbonne, P., and Roy, R. (2009) Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival. Nature 457, 210-214
30. Kage-Nakadai, E., Kobuna, H., Kimura, M., Gengyo-Ando, K., Inoue, T., Arai, H., and Mitani, S. (2010) Two very long chain fatty acid acyl-CoA synthetase genes, acs-20 and acs-22, have roles in the cuticle surface barrier in Caenorhabditis elegans. PloS One 5, e8857
31. Ozeki, S., Cheng, J., Tauchi-Sato, K., Hatano, N., Taniguchi, H., and Fujimoto, T. (2005) Rab18 localizes to lipid droplets and induces their close apposition to the endoplasmic reticulum-derived membrane. J. Cell Sci. 118, 2601-2611
32. Guo, Y., Walther, T. C., Rao, M., Stuurman, N., Goshima, G., Terayama, K., Wong, J. S., Vale, R. D., Walter, P., and Farese, R. V. (2008) Functional genomic screen reveals genes involved in lipid-droplet formation and utilization. Nature 453, 657-661
33. Kubagawa, H. M., Watts, J. L., Corrigan, C., Edmonds, J. W., Sztul, E., Browse, J., and Miller, M. A. (2006) Oocyte signals derived from polyunsaturated fatty acids control sperm recruitment in vivo. Nat. Cell Biol. 8, 1143-1148
34. Murphy, S., Martin, S., and Parton, R. G. (2009) Lipid droplet-organelle interactions; sharing the fats. Biochim. Biophys. Acta 1791, 441-447
35. Goodman, J. M. (2008) The gregarious lipid droplet. J. Biol. Chem. 283, 28005-28009
36. Pu, J., Ha, C. W., Zhang, S., Jung, J. P., Huh, W. K., and Liu, P. (2011) Interactomic study on interaction between lipid droplets and mitochondria. Protein & cell 2, 487-496
37. Hellerer, T., Axäng, C., Brackmann, C., Hillertz, P., Pilon, M., and Enejder, A. (2007) Monitoring of lipid storage in Caenorhabditis elegans using coherent anti-Stokes Raman scattering (CARS) microscopy. Proc. Natl. Acad. Sci. U. S. A. 104, 14658-14663
38. Yen, K., Le, T. T., Bansal, A., Narasimhan, S. D., Cheng, J. X., and Tissenbaum, H. A. (2010) A comparative study of fat storage quantitation in nematode Caenorhabditis elegans using label and label-free methods. PloS one 5, e12810
39. Zhang, H., Wang, Y., Li, J., Yu, J., Pu, J., Li, L., Zhang, H., Zhang, S., Peng, G., Yang, F., and Liu, P. (2011) Proteome of skeletal muscle lipid droplet reveals association with mitochondria and apolipoprotein a-I. J. Proteome Res. 10, 4757-4768
40. Turró, S., Ingelmo-Torres, M., Estanyol, J. M., Tebar, F., Fernández, M. A., Albor, C. V., Gaus, K., Grewal, T., Enrich, C., and Pol, A. (2006) Identification and characterization of associated with lipid droplet protein 1: A novel membrane-associated protein that resides on hepatic lipid droplets. Traffic 7, 1254-1269
41. Sato, S., Fukasawa, M., Yamakawa, Y., Natsume, T., Suzuki, T., Shoji, I., Aizaki, H., Miyamura, T., and Nishijima, M. (2006) Proteomic profiling of lipid droplet proteins in hepatoma cell lines expressing hepatitis C virus core protein. J. Biochem. 139, 921-930
42. Wan, H. C., Melo, R. C., Jin, Z., Dvorak, A. M., and Weller, P. F. (2007) Roles and origins of leukocyte lipid bodies: proteomic and ultrastructural studies. FASEB J. 21, 167-178
43. Katavic, V., Agrawal, G. K., Hajduch, M., Harris, S. L., and Thelen, J. J. (2006) Protein and lipid composition analysis of oil bodies from two Brassica napus cultivars. Proteomics 6, 4586-4598
44. Kim, S. C., Chen, Y., Mirza, S., Xu, Y., Lee, J., Liu, P., and Zhao, Y. (2006) A clean, more efficient method for in-solution digestion of protein mixtures without detergent or urea. J. Proteome Res. 5, 3446-3452
45. Bouchoux, J., Beilstein, F., Pauquai, T., Guerrera, I. C., Chateau, D., Ly, N., Alqub, M., Klein, C., Chambaz, J., Rousset, M., Lacorte, J. M., Morel, E., and Demignot, S. (2011) The proteome of cytosolic lipid droplets isolated from differentiated Caco-2/TC7 enterocytes reveals cell-specific characteristics. Biol. Cell 103, 499-517
46. Ding, Y., Yang, L., Zhang, S., Wang, Y., Du, Y., Pu, J., Peng, G., Chen, Y., Zhang, H., Yu, J., Hang, H., Wu, P., Yang, F., Yang, H., Steinbuchel, A., and Liu, P. (2011) Identification of the major functional proteins of Prokaryotic lipid droplets. J. Lipid Res. 53, 399-411