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Volumn 21, Issue 11, 2014, Pages 949-954

DNA methylation: Old dog, new tricks?

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EID: 84908876468     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2910     Document Type: Review
Times cited : (74)

References (84)
  • 1
    • 0034625064 scopus 로고    scopus 로고
    • Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a
    • Ramsahoye, B.H. et al. Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc. Natl. Acad. Sci. USA 97, 5237-5242 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 5237-5242
    • Ramsahoye, B.H.1
  • 2
    • 84879663784 scopus 로고    scopus 로고
    • Global epigenomic reconfiguration during mammalian brain development
    • Lister, R. et al. Global epigenomic reconfiguration during mammalian brain development. Science 341, 1237905 (2013).
    • (2013) Science , vol.341 , pp. 1237905
    • Lister, R.1
  • 3
    • 78751470921 scopus 로고    scopus 로고
    • Structure and function of mammalian DNA methyltransferases
    • Jurkowska, R.Z., Jurkowski, T.P. &Jeltsch, A. Structure and function of mammalian DNA methyltransferases. ChemBioChem 12, 206-222 (2011).
    • (2011) ChemBioChem , vol.12 , pp. 206-222
    • Jurkowska, R.Z.1    Jurkowski, T.P.2    Jeltsch, A.3
  • 4
    • 84863889319 scopus 로고    scopus 로고
    • In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases
    • Arand, J. et al. In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases. PLoS Genet. 8, e1002750 (2012).
    • (2012) PLoS Genet , vol.8 , pp. e1002750
    • Arand, J.1
  • 5
    • 0036135014 scopus 로고    scopus 로고
    • Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements
    • Liang, G. et al. Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements. Mol. Cell. Biol. 22, 480-491 (2002).
    • (2002) Mol. Cell. Biol , vol.22 , pp. 480-491
    • Liang, G.1
  • 6
    • 0024673303 scopus 로고
    • CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation
    • Iguchi-Ariga, S.M. &Schaffner, W. CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation. Genes Dev. 3, 612-619 (1989).
    • (1989) Genes Dev , vol.3 , pp. 612-619
    • Iguchi-Ariga, S.M.1    Schaffner, W.2
  • 8
    • 0025981310 scopus 로고
    • Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region
    • Prendergast, G.C. &Ziff, E.B. Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region. Science 251, 186-189 (1991).
    • (1991) Science , vol.251 , pp. 186-189
    • Prendergast, G.C.1    Ziff, E.B.2
  • 9
    • 84888994574 scopus 로고    scopus 로고
    • Cross-talk between site-specific transcription factors and DNA methylation states
    • Blattler, A. &Farnham, P.J. Cross-talk between site-specific transcription factors and DNA methylation states. J. Biol. Chem. 288, 34287-34294 (2013).
    • (2013) J. Biol. Chem , vol.288 , pp. 34287-34294
    • Blattler, A.1    Farnham, P.J.2
  • 10
    • 0037151042 scopus 로고    scopus 로고
    • Methyl-CpG binding domain protein 2 represses transcription from hypermethylated-class glutathione S-transferase gene promoters in hepatocellular carcinoma cells
    • Bakker, J., Lin, X. &Nelson, W.G. Methyl-CpG binding domain protein 2 represses transcription from hypermethylated-class glutathione S-transferase gene promoters in hepatocellular carcinoma cells. J. Biol. Chem. 277, 22573-22580 (2002).
    • (2002) J. Biol. Chem , vol.277 , pp. 22573-22580
    • Bakker, J.1    Lin, X.2    Nelson, W.G.3
  • 11
    • 12244253036 scopus 로고    scopus 로고
    • MBD3L1 and MBD3L2, two new proteins homologous to the methyl-CpG-binding proteins MBD2 and MBD3: Characterization of MBD3L1 as a testis-specific transcriptional repressor
    • Jiang, C.L. et al. MBD3L1 and MBD3L2, two new proteins homologous to the methyl-CpG-binding proteins MBD2 and MBD3: characterization of MBD3L1 as a testis-specific transcriptional repressor. Genomics 80, 621-629 (2002).
    • (2002) Genomics , vol.80 , pp. 621-629
    • Jiang, C.L.1
  • 12
    • 84876278080 scopus 로고    scopus 로고
    • Methylation-dependent and-independent genomic targeting principles of the MBD protein family
    • Baubec, T. et al. Methylation-dependent and-independent genomic targeting principles of the MBD protein family. Cell 153, 480-492 (2013).
    • (2013) Cell , vol.153 , pp. 480-492
    • Baubec, T.1
  • 13
    • 0036241916 scopus 로고    scopus 로고
    • Molecular mechanisms of gene silencing mediated by DNA methylation
    • Curradi, M. et al. Molecular mechanisms of gene silencing mediated by DNA methylation. Mol. Cell. Biol. 22, 3157-3173 (2002).
    • (2002) Mol. Cell. Biol , vol.22 , pp. 3157-3173
    • Curradi, M.1
  • 14
    • 84896324622 scopus 로고    scopus 로고
    • Dnmt1-independent CG methylation contributes to nucleosome positioning in diverse eukaryotes
    • Huff, J.T. &Zilberman, D. Dnmt1-independent CG methylation contributes to nucleosome positioning in diverse eukaryotes. Cell 156, 1286-1297 (2014).
    • (2014) Cell , vol.156 , pp. 1286-1297
    • Huff, J.T.1    Zilberman, D.2
  • 15
    • 77951116072 scopus 로고    scopus 로고
    • CpG islands influence chromatin structure via the CpG-binding protein Cfp1
    • Thomson, J.P. et al. CpG islands influence chromatin structure via the CpG-binding protein Cfp1. Nature 464, 1082-1086 (2010).
    • (2010) Nature , vol.464 , pp. 1082-1086
    • Thomson, J.P.1
  • 16
    • 84878988149 scopus 로고    scopus 로고
    • KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands
    • Farcas, A.M. et al. KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands. Elife 1, e00205 (2012).
    • (2012) Elife , vol.1 , pp. e00205
    • Farcas, A.M.1
  • 17
    • 84902127230 scopus 로고    scopus 로고
    • Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and Polycomb domain formation
    • Blackledge, N.P. et al. Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and Polycomb domain formation. Cell 157, 1445-1459 (2014).
    • (2014) Cell , vol.157 , pp. 1445-1459
    • Blackledge, N.P.1
  • 18
    • 0031104930 scopus 로고    scopus 로고
    • DNA methylation directs a time-dependent repression of transcription initiation
    • Kass, S.U., Landsberger, N. &Wolffe, A.P. DNA methylation directs a time-dependent repression of transcription initiation. Curr. Biol. 7, 157-165 (1997).
    • (1997) Curr. Biol , vol.7 , pp. 157-165
    • Kass, S.U.1    Landsberger, N.2    Wolffe, A.P.3
  • 19
    • 0031837109 scopus 로고    scopus 로고
    • Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
    • Jones, P.L. et al. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat. Genet. 19, 187-191 (1998).
    • (1998) Nat. Genet , vol.19 , pp. 187-191
    • Jones, P.L.1
  • 20
    • 79955068902 scopus 로고    scopus 로고
    • Biological functions of methyl-CpG-binding proteins
    • Defossez, P.A. &Stancheva, I. Biological functions of methyl-CpG-binding proteins. Prog. Mol. Biol. Transl. Sci. 101, 377-398 (2011).
    • (2011) Prog. Mol. Biol. Transl. Sci , vol.101 , pp. 377-398
    • Defossez, P.A.1    Stancheva, I.2
  • 21
    • 69249220176 scopus 로고    scopus 로고
    • DNA methylation and methyl-CpG binding proteins: Developmental requirements and function
    • Bogdanović , O. &Veenstra, G.J. DNA methylation and methyl-CpG binding proteins: developmental requirements and function. Chromosoma 118, 549-565 (2009).
    • (2009) Chromosoma , vol.118 , pp. 549-565
    • Bogdanović, O.1    Veenstra, G.J.2
  • 22
    • 33645218438 scopus 로고    scopus 로고
    • A family of human zinc finger proteins that bind methylated DNA and repress transcription
    • Filion, G.J. et al. A family of human zinc finger proteins that bind methylated DNA and repress transcription. Mol. Cell. Biol. 26, 169-181 (2006).
    • (2006) Mol. Cell. Biol , vol.26 , pp. 169-181
    • Filion, G.J.1
  • 23
    • 77957809220 scopus 로고    scopus 로고
    • The human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNA
    • Laget, S. et al. The human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNA. PLoS ONE 5, e11982 (2010).
    • (2010) PLoS ONE , vol.5 , pp. e11982
    • Laget, S.1
  • 24
    • 0030969516 scopus 로고    scopus 로고
    • Histone deacetylases associated with the mSin3 corepressor mediate Mad transcriptional repression
    • Laherty, C.D. et al. Histone deacetylases associated with the mSin3 corepressor mediate Mad transcriptional repression. Cell 89, 349-356 (1997).
    • (1997) Cell , vol.89 , pp. 349-356
    • Laherty, C.D.1
  • 25
    • 0030953186 scopus 로고    scopus 로고
    • Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase
    • Nagy, L. et al. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell 89, 373-380 (1997).
    • (1997) Cell , vol.89 , pp. 373-380
    • Nagy, L.1
  • 26
    • 84883462358 scopus 로고    scopus 로고
    • Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor
    • Lyst, M.J. et al. Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor. Nat. Neurosci. 16, 898-902 (2013).
    • (2013) Nat. Neurosci , vol.16 , pp. 898-902
    • Lyst, M.J.1
  • 27
    • 31344465966 scopus 로고    scopus 로고
    • MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties
    • Le Guezennec, X. et al. MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties. Mol. Cell. Biol. 26, 843-851 (2006).
    • (2006) Mol. Cell. Biol , vol.26 , pp. 843-851
    • Le Guezennec, X.1
  • 28
    • 0032871399 scopus 로고    scopus 로고
    • MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
    • Ng, H.H. et al. MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex. Nat. Genet. 23, 58-61 (1999).
    • (1999) Nat. Genet , vol.23 , pp. 58-61
    • Ng, H.H.1
  • 29
    • 0034772724 scopus 로고    scopus 로고
    • Promoter hypermethylation of multiple genes in carcinoma of the uterine cervix
    • Dong, S.M. et al. Promoter hypermethylation of multiple genes in carcinoma of the uterine cervix. Clin. Cancer Res. 7, 1982-1986 (2001).
    • (2001) Clin. Cancer Res , vol.7 , pp. 1982-1986
    • Dong, S.M.1
  • 30
    • 0000031048 scopus 로고    scopus 로고
    • Transcriptional repression of the transforming growth factor-type i receptor gene by DNA methylation results in the development of TGF-resistance in human gastric cancer
    • Kang, S.H. et al. Transcriptional repression of the transforming growth factor-type I receptor gene by DNA methylation results in the development of TGF-resistance in human gastric cancer. Oncogene 18, 7280-7286 (1999).
    • (1999) Oncogene , vol.18 , pp. 7280-7286
    • Kang, S.H.1
  • 31
    • 0031985868 scopus 로고    scopus 로고
    • In vitro reactivation of the FMR1 gene involved in fragile X syndrome
    • Chiurazzi, P. et al. In vitro reactivation of the FMR1 gene involved in fragile X syndrome. Hum. Mol. Genet. 7, 109-113 (1998).
    • (1998) Hum. Mol. Genet , vol.7 , pp. 109-113
    • Chiurazzi, P.1
  • 32
    • 0037224722 scopus 로고    scopus 로고
    • DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells
    • Robert, M.F. et al. DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells. Nat. Genet. 33, 61-65 (2003).
    • (2003) Nat. Genet , vol.33 , pp. 61-65
    • Robert, M.F.1
  • 33
    • 80053443628 scopus 로고    scopus 로고
    • A SILAC-based screen for methyl-CpG binding proteins identifies RBP-J as a DNA methylation and sequence-specific binding protein
    • Bartels, S.J. et al. A SILAC-based screen for methyl-CpG binding proteins identifies RBP-J as a DNA methylation and sequence-specific binding protein. PLoS ONE 6, e25884 (2011).
    • (2011) PLoS ONE , vol.6 , pp. e25884
    • Bartels, S.J.1
  • 34
    • 77958481159 scopus 로고    scopus 로고
    • Nucleosome-interacting proteins regulated by DNA and histone methylation
    • Bartke, T. et al. Nucleosome-interacting proteins regulated by DNA and histone methylation. Cell 143, 470-484 (2010).
    • (2010) Cell , vol.143 , pp. 470-484
    • Bartke, T.1
  • 35
    • 59949099230 scopus 로고    scopus 로고
    • A SILAC-based DNA protein interaction screen that identifies candidate binding proteins to functional DNA elements
    • Mittler, G., Butter, F. &Mann, M. A SILAC-based DNA protein interaction screen that identifies candidate binding proteins to functional DNA elements. Genome Res. 19, 284-293 (2009).
    • (2009) Genome Res , vol.19 , pp. 284-293
    • Mittler, G.1    Butter, F.2    Mann, M.3
  • 36
    • 84874771985 scopus 로고    scopus 로고
    • Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives
    • Spruijt, C.G. et al. Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives. Cell 152, 1146-1159 (2013).
    • (2013) Cell , vol.152 , pp. 1146-1159
    • Spruijt, C.G.1
  • 37
    • 84884692057 scopus 로고    scopus 로고
    • DNA methylation presents distinct binding sites for human transcription factors
    • Hu, S. et al. DNA methylation presents distinct binding sites for human transcription factors. Elife 2, e00726 (2013).
    • (2013) Elife , vol.2 , pp. e00726
    • Hu, S.1
  • 38
    • 84899840015 scopus 로고    scopus 로고
    • Structural basis for Klf4 recognition of methylated DNA
    • Liu, Y. et al. Structural basis for Klf4 recognition of methylated DNA. Nucleic Acids Res. 42, 4859-4867 (2014).
    • (2014) Nucleic Acids Res , vol.42 , pp. 4859-4867
    • Liu, Y.1
  • 39
    • 36148960428 scopus 로고    scopus 로고
    • Reprogramming somatic cells towards pluripotency by defined factors
    • Lewitzky, M. &Yamanaka, S. Reprogramming somatic cells towards pluripotency by defined factors. Curr. Opin. Biotechnol. 18, 467-473 (2007).
    • (2007) Curr. Opin. Biotechnol , vol.18 , pp. 467-473
    • Lewitzky, M.1    Yamanaka, S.2
  • 40
    • 84868556202 scopus 로고    scopus 로고
    • An atomic model of Zfp57 recognition of CpG methylation within a specific DNA sequence
    • Liu, Y. et al. An atomic model of Zfp57 recognition of CpG methylation within a specific DNA sequence. Genes Dev. 26, 2374-2379 (2012).
    • (2012) Genes Dev , vol.26 , pp. 2374-2379
    • Liu, Y.1
  • 41
    • 78650584064 scopus 로고    scopus 로고
    • CpG methylation of half-CRE sequences creates C/EBPα binding sites that activate some tissue-specific genes
    • Rishi, V. et al. CpG methylation of half-CRE sequences creates C/EBPα binding sites that activate some tissue-specific genes. Proc. Natl. Acad. Sci. USA 107, 20311-20316 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 20311-20316
    • Rishi, V.1
  • 42
    • 77956120147 scopus 로고    scopus 로고
    • Sequence-specific recognition of methylated DNA by human zinc-finger proteins
    • Sasai, N., Nakao, M. &Defossez, P.A. Sequence-specific recognition of methylated DNA by human zinc-finger proteins. Nucleic Acids Res. 38, 5015-5022 (2010).
    • (2010) Nucleic Acids Res , vol.38 , pp. 5015-5022
    • Sasai, N.1    Nakao, M.2    Defossez, P.A.3
  • 43
    • 48349092985 scopus 로고    scopus 로고
    • Hypomethylation of multiple imprinted loci in individuals with transient neonatal diabetes is associated with mutations in ZFP57
    • Mackay, D.J. et al. Hypomethylation of multiple imprinted loci in individuals with transient neonatal diabetes is associated with mutations in ZFP57. Nat. Genet. 40, 949-951 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 949-951
    • Mackay, D.J.1
  • 44
    • 80555156105 scopus 로고    scopus 로고
    • In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions
    • Quenneville, S. et al. In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions. Mol. Cell 44, 361-372 (2011).
    • (2011) Mol. Cell , vol.44 , pp. 361-372
    • Quenneville, S.1
  • 45
    • 84861883921 scopus 로고    scopus 로고
    • Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk
    • Brinkman, A.B. et al. Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk. Genome Res. 22, 1128-1138 (2012).
    • (2012) Genome Res , vol.22 , pp. 1128-1138
    • Brinkman, A.B.1
  • 46
    • 66149146320 scopus 로고    scopus 로고
    • Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
    • Tahiliani, M. et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324, 930-935 (2009).
    • (2009) Science , vol.324 , pp. 930-935
    • Tahiliani, M.1
  • 47
    • 66149123748 scopus 로고    scopus 로고
    • The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
    • Kriaucionis, S. &Heintz, N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 324, 929-930 (2009).
    • (2009) Science , vol.324 , pp. 929-930
    • Kriaucionis, S.1    Heintz, N.2
  • 48
    • 77954842819 scopus 로고    scopus 로고
    • Quantification of the sixth DNA base hydroxymethylcytosine in the brain
    • Mnzel, M. et al. Quantification of the sixth DNA base hydroxymethylcytosine in the brain. Angew. Chem. Int. Edn Engl. 49, 5375-5377 (2010).
    • (2010) Angew. Chem. Int. Edn Engl , vol.49 , pp. 5375-5377
    • Mnzel, M.1
  • 49
    • 80052461558 scopus 로고    scopus 로고
    • Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
    • Ito, S. et al. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 333, 1300-1303 (2011).
    • (2011) Science , vol.333 , pp. 1300-1303
    • Ito, S.1
  • 50
    • 84908881858 scopus 로고    scopus 로고
    • TDG excision of fC may be a predominant element of pathways for active DNA demethylation
    • Maiti, A. et al. TDG excision of fC may be a predominant element of pathways for active DNA demethylation. FASEB J. 27, 758.6 (2013).
    • (2013) FASEB J , vol.27 , pp. 7586
    • Maiti, A.1
  • 51
    • 84892763878 scopus 로고    scopus 로고
    • Reversing DNA methylation: Mechanisms, genomics, and biological functions
    • Wu, H. &Zhang, Y. Reversing DNA methylation: mechanisms, genomics, and biological functions. Cell 156, 45-68 (2014).
    • (2014) Cell , vol.156 , pp. 45-68
    • Wu, H.1    Zhang, Y.2
  • 52
    • 84886035297 scopus 로고    scopus 로고
    • A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation
    • Iurlaro, M. et al. A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation. Genome Biol. 14, R119 (2013).
    • (2013) Genome Biol , vol.14 , pp. R119
    • Iurlaro, M.1
  • 53
    • 84871563384 scopus 로고    scopus 로고
    • MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system
    • Mellén, M. et al. MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell 151, 1417-1430 (2012).
    • (2012) Cell , vol.151 , pp. 1417-1430
    • Mellén, M.1
  • 54
    • 84860221291 scopus 로고    scopus 로고
    • Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation
    • Hashimoto, H. et al. Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation. Nucleic Acids Res. 40, 4841-4849 (2012).
    • (2012) Nucleic Acids Res , vol.40 , pp. 4841-4849
    • Hashimoto, H.1
  • 55
    • 4043112183 scopus 로고    scopus 로고
    • Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2
    • Valinluck, V. et al. Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2). Nucleic Acids Res. 32, 4100-4108 (2004).
    • (2004) Nucleic Acids Res , vol.32 , pp. 4100-4108
    • Valinluck, V.1
  • 56
    • 84901911200 scopus 로고    scopus 로고
    • Unusual characteristics of the DNA binding domain of epigenetic regulatory protein MeCP2 determine its binding specificity
    • Khrapunov, S. et al. Unusual characteristics of the DNA binding domain of epigenetic regulatory protein MeCP2 determine its binding specificity. Biochemistry 53, 3379-3391 (2014).
    • (2014) Biochemistry , vol.53 , pp. 3379-3391
    • Khrapunov, S.1
  • 57
    • 84455167621 scopus 로고    scopus 로고
    • Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells
    • Yildirim, O. et al. Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells. Cell 147, 1498-1510 (2011).
    • (2011) Cell , vol.147 , pp. 1498-1510
    • Yildirim, O.1
  • 58
    • 79959431845 scopus 로고    scopus 로고
    • Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain
    • Frauer, C. et al. Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain. PLoS ONE 6, e21306 (2011).
    • (2011) PLoS ONE , vol.6 , pp. e21306
    • Frauer, C.1
  • 59
    • 84901950311 scopus 로고    scopus 로고
    • Structural basis for hydroxymethylcytosine recognition by the SRA domain of UHRF2
    • Zhou, T. et al. Structural basis for hydroxymethylcytosine recognition by the SRA domain of UHRF2. Mol. Cell 54, 879-886 (2014).
    • (2014) Mol. Cell , vol.54 , pp. 879-886
    • Zhou, T.1
  • 60
    • 84861221693 scopus 로고    scopus 로고
    • Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution
    • Booth, M.J. et al. Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution. Science 336, 934-937 (2012).
    • (2012) Science , vol.336 , pp. 934-937
    • Booth, M.J.1
  • 61
    • 84868266802 scopus 로고    scopus 로고
    • Selective capture of 5-hydroxymethylcytosine from genomic DNA
    • Li, Y., Song, C.X., He, C. &Jin, P. Selective capture of 5-hydroxymethylcytosine from genomic DNA. J. Vis. Exp. 68, e4441 (2012).
    • (2012) J. Vis. Exp , vol.68 , pp. e4441
    • Li, Y.1    Song, C.X.2    He, C.3    Jin, P.4
  • 62
    • 84876907152 scopus 로고    scopus 로고
    • Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming
    • Song, C.X. et al. Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming. Cell 153, 678-691 (2013).
    • (2013) Cell , vol.153 , pp. 678-691
    • Song, C.X.1
  • 63
    • 84860389965 scopus 로고    scopus 로고
    • Genome-wide profiling of DNA methylation in human cancer cells
    • Ogoshi, K. et al. Genome-wide profiling of DNA methylation in human cancer cells. Genomics 98, 280-287 (2011).
    • (2011) Genomics , vol.98 , pp. 280-287
    • Ogoshi, K.1
  • 64
    • 78751693154 scopus 로고    scopus 로고
    • Replication timing-related and gene body-specific methylation of active human genes
    • Aran, D. et al. Replication timing-related and gene body-specific methylation of active human genes. Hum. Mol. Genet. 20, 670-680 (2011).
    • (2011) Hum. Mol. Genet , vol.20 , pp. 670-680
    • Aran, D.1
  • 65
    • 33847304609 scopus 로고    scopus 로고
    • Gene body-specific methylation on the active X chromosome
    • Hellman, A. &Chess, A. Gene body-specific methylation on the active X chromosome. Science 315, 1141-1143 (2007).
    • (2007) Science , vol.315 , pp. 1141-1143
    • Hellman, A.1    Chess, A.2
  • 66
    • 84867145980 scopus 로고    scopus 로고
    • On the presence and role of human gene-body DNA methylation
    • Jjingo, D. et al. On the presence and role of human gene-body DNA methylation. Oncotarget 3, 462-474 (2012).
    • (2012) Oncotarget , vol.3 , pp. 462-474
    • Jjingo, D.1
  • 67
    • 77954504873 scopus 로고    scopus 로고
    • Conserved role of intragenic DNA methylation in regulating alternative promoters
    • Maunakea, A.K. et al. Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature 466, 253-257 (2010).
    • (2010) Nature , vol.466 , pp. 253-257
    • Maunakea, A.K.1
  • 68
    • 84864612696 scopus 로고    scopus 로고
    • Genome-wide DNA methylation profiles in hematopoietic stem and progenitor cells reveal overrepresentation of ETS transcription factor binding sites
    • Hogart, A. et al. Genome-wide DNA methylation profiles in hematopoietic stem and progenitor cells reveal overrepresentation of ETS transcription factor binding sites. Genome Res. 22, 1407-1418 (2012).
    • (2012) Genome Res , vol.22 , pp. 1407-1418
    • Hogart, A.1
  • 69
    • 84885021247 scopus 로고    scopus 로고
    • Epigenetic memory at embryonic enhancers identified in DNA methylation maps from adult mouse tissues
    • Hon, G.C. et al. Epigenetic memory at embryonic enhancers identified in DNA methylation maps from adult mouse tissues. Nat. Genet. 45, 1198-1206 (2013).
    • (2013) Nat. Genet , vol.45 , pp. 1198-1206
    • Hon, G.C.1
  • 70
    • 84882884517 scopus 로고    scopus 로고
    • Charting a dynamic DNA methylation landscape of the human genome
    • Ziller, M.J. et al. Charting a dynamic DNA methylation landscape of the human genome. Nature 500, 477-481 (2013).
    • (2013) Nature , vol.500 , pp. 477-481
    • Ziller, M.J.1
  • 71
    • 84878282421 scopus 로고    scopus 로고
    • Epigenomic analysis of multilineage differentiation of human embryonic stem cells
    • Xie, W. et al. Epigenomic analysis of multilineage differentiation of human embryonic stem cells. Cell 153, 1134-1148 (2013).
    • (2013) Cell , vol.153 , pp. 1134-1148
    • Xie, W.1
  • 72
    • 84868198427 scopus 로고    scopus 로고
    • Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia
    • Kulis, M. et al. Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia. Nat. Genet. 44, 1236-1242 (2012).
    • (2012) Nat. Genet , vol.44 , pp. 1236-1242
    • Kulis, M.1
  • 73
    • 84871702441 scopus 로고    scopus 로고
    • The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells
    • Seisenberger, S. et al. The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells. Mol. Cell 48, 849-862 (2012).
    • (2012) Mol. Cell , vol.48 , pp. 849-862
    • Seisenberger, S.1
  • 74
    • 84905911865 scopus 로고    scopus 로고
    • Chromatin and transcription transitions of mammalian adult germline stem cells and spermatogenesis
    • Hammoud, S.S. et al. Chromatin and transcription transitions of mammalian adult germline stem cells and spermatogenesis. Cell Stem Cell 15, 239-253 (2014).
    • (2014) Cell Stem Cell , vol.15 , pp. 239-253
    • Hammoud, S.S.1
  • 75
    • 80051558092 scopus 로고    scopus 로고
    • Temporal uncoupling of the DNA methylome and transcriptional repression during embryogenesis
    • Bogdanovic, O. et al. Temporal uncoupling of the DNA methylome and transcriptional repression during embryogenesis. Genome Res. 21, 1313-1327 (2011).
    • (2011) Genome Res , vol.21 , pp. 1313-1327
    • Bogdanovic, O.1
  • 76
    • 38649126918 scopus 로고    scopus 로고
    • Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation
    • Fouse, S.D. et al. Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation. Cell Stem Cell 2, 160-169 (2008).
    • (2008) Cell Stem Cell , vol.2 , pp. 160-169
    • Fouse, S.D.1
  • 77
    • 84895801889 scopus 로고    scopus 로고
    • Genomic patterns and context specific interpretation of DNA methylation
    • Baubec, T. &Schubeler, D. Genomic patterns and context specific interpretation of DNA methylation. Curr. Opin. Genet. Dev. 25, 85-92 (2014).
    • (2014) Curr. Opin. Genet. Dev , vol.25 , pp. 85-92
    • Baubec, T.1    Schubeler, D.2
  • 78
    • 84863986133 scopus 로고    scopus 로고
    • Functions of DNA methylation: Islands, start sites, gene bodies and beyond
    • Jones, P.A. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat. Rev. Genet. 13, 484-492 (2012).
    • (2012) Nat. Rev. Genet , vol.13 , pp. 484-492
    • Jones, P.A.1
  • 79
    • 0026583975 scopus 로고
    • Repression of genes by DNA methylation depends on CpG density and promoter strength: Evidence for involvement of a methyl-CpG binding protein
    • Boyes, J. &Bird, A. Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein. EMBO J. 11, 327-333 (1992).
    • (1992) EMBO J , vol.11 , pp. 327-333
    • Boyes, J.1    Bird, A.2
  • 80
    • 0028106737 scopus 로고
    • Dependence of transcriptional repression on CpG methylation density
    • Hsieh, C.L. Dependence of transcriptional repression on CpG methylation density. Mol. Cell. Biol. 14, 5487-5494 (1994).
    • (1994) Mol. Cell. Biol , vol.14 , pp. 5487-5494
    • Hsieh, C.L.1
  • 81
    • 84904044398 scopus 로고    scopus 로고
    • Alternative splicing of MBD2 supports self-renewal in human pluripotent stem cells
    • Lu, Y. et al. Alternative splicing of MBD2 supports self-renewal in human pluripotent stem cells. Cell Stem Cell 15, 192-101 (2014).
    • (2014) Cell Stem Cell , vol.15 , pp. 192-101
    • Lu, Y.1
  • 82
    • 63849239275 scopus 로고    scopus 로고
    • Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function
    • Tao, J. et al. Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function. Proc. Natl. Acad. Sci. USA 106, 4882-4887 (2009).
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 4882-4887
    • Tao, J.1
  • 83
    • 77953228178 scopus 로고    scopus 로고
    • Kaiso regulates Znf131-mediated transcriptional activation
    • Donaldson, N.S. et al. Kaiso regulates Znf131-mediated transcriptional activation. Exp. Cell Res. 316, 1692-1705 (2010).
    • (2010) Exp. Cell Res , vol.316 , pp. 1692-1705
    • Donaldson, N.S.1
  • 84
    • 0027440294 scopus 로고
    • Distinct DNA binding preferences for the c-Myc/Max and Max/Max dimers
    • Solomon, D.L., Amati, B. &Land, H. Distinct DNA binding preferences for the c-Myc/Max and Max/Max dimers. Nucleic Acids Res. 21, 5372-5376 (1993).
    • (1993) Nucleic Acids Res , vol.21 , pp. 5372-5376
    • Solomon, D.L.1    Amati, B.2    Land, H.3


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