DNA methylation directs a time-dependent repression of transcription initiation

Current Biology

Volumn 7, Issue 3, 1997, Pages 157-165

  Kass, Stefan U ^a   Landsberger, Nicoletta ^a   Wolffe, Alan P ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0031104930     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(97)70086-1     Document Type: Article

References (35)

1. Li E, Beard C, Jaenisch R: Role of DNA methylation in genomic imprinting. Nature 1993, 366:362-365.
2. Li E, Bestor TH, Jaenisch R: Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992, 69:915-926.
3. McGrath J, Solter D: Completion of mouse embryogenesis requires both the maternal and paternal genomes. Cell 1984, 37:179-183.
4. Surani MA: Genomic imprinting: silence of the genes. Nature 1993, 366:302-303.
5. Bartolomei MS, Webber AL, Brunkow ME, Tilghman SM: Epigenetic mechanism underlying the imprinting of the mouse H19 gene. Genes Dev 1993, 7:1663-1673.
6. Tremblay KD, Saam JR, Ingram RS, Tilghman SM, Bartolemei MS: A paternal-specific methylation imprint marks the alleles of the mouse H19 gene. Nat Genet 1995, 9:407-413.
7. Stoger R, Kubicka P, Liu CG, Kafri T, Razin A, Cedar H, Barlow DP: Maternal specific methylation of the imprinted Igf2r locus identifies the expressed locus as carrying the imprinting signal. Cell 1993, 73:61-71.
8. Monk M: Changes in DNA methylation during mouse embryonic development in relation to X chromosome activity and imprinting. Phil Trans R Soc London B 1990, 326:179-187.
9. Feil R, Walter J, Allen ND, Reik W: Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes. Development 1994, 120:2933-2943.
10. Ferguson-Smith AC, Sasaki H, Cattanach BM, Surani MA: Parentalorigin-specific epigenetic modification of the mouse H19 gene. Nature 1993, 362:751-754.
11. Norris DP, Patel D, Kay GF, Penney GD, Brockdorff N, Sheardown SA, et al.: Evidence that random and imprinted Xist expression is controlled by pre-emptive methylation. Cell 1994, 77:41-51.
12. Murray EJ, Grosveld F: Site specific demethylation in the promoter of the human γ globin gene does not alleviate methylation mediated suppression. EMBO J 1987, 6:2329-2335.
13. Levine A, Yeivin A, Ben-Asher E, Aloni Y, Razin A: Histone H1-mediated inhibition of transcription initiation of methylated templates in vitro. J Biol Chem 1993, 268:21754-21759.
14. Iguchi-Ariga XMM, Schaffner W: CpG methylation of the cAMP responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation. Genes Dev 1989, 3:612-619.
15. McArthur M, Thomas JO: A preference of histone H1 for methylated DNA. EMBO J 1996, 15:1705-1714.
16. Ball DJ, Gross DS, Garard WT: 5-methylcytosine is localised in nucleosomes that contain H1. Proc Natl Acad Sci USA 1983, 80:5490-5494.
17. Boyes J, Bird A: DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein. Cell 1991, 64:1123-1134.
18. Jost JP, Hofsteenge J: The repressor MDBP-2 is a member of the histone H1 family that binds preferentially in vitro and in vivo to methylated non specific DNA sequences. Proc Natl Acad Sci USA 1992, 89:9499-9503.
19. Razin A, Cedar H: Distribution of 5-methylcytosine in chromatin. Proc Natl Acad Sci USA 1977, 74:2725-2728.
20. Buschausen G, Wittig B, Graessmann M, Graessmann A: Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene. Proc Natl Acad Sci USA 11987, 84:1177-1181.
21. Graessmann A, Graessmann M: DNA methylation, chromatin structure and regulation of Herpes simplex virus tk gene expression. Gene 1988, 74:135-137.
22. Kass SU, Goddard JP, Adams RLP: Inactive chromatin spreads from a focus of methylation. Mol Cell Biol 1994, 13:7372-7379.
23. Riggs A, Pfeifer GP: X-chromosome inactivation and cell memory. Trends Genet 1992, 8:169-174.
24. Keshet I, Lieman-Hurwitz J, Cedar H: DNA methylation affects the formation of active chromatin. Cell 1986, 44:535-543.
25. Hsieh CL: Dependence of transcriptional repression on CpG methylation density. Mol Cell Biol 1994, 14:5487-5494.
26. Rougvie AE, Lis JT: The RNA polymerase II molecule at the 5′ end of the uninduced hsp 70 gene of D. melanogaster is transcriptionally engaged. Cell 1988, 54:795-804.
27. Landsberger N, Wolffe AP: Role of chromatin and Xenopus heat shock transcription factor (XHSF1) in the regulation of the Xenopus hsp70 promoter in vivo. Mol Cell Biol 1995 15:6013-6024.
28. Laybourn PJ, Kadonaga JT: Role of nucleosome cores and histone H1 in regulation of transcription by RNA polymerase II. Science 1991, 254:238-245.
29. Bird A: The essentials of DNA methylation. Cell 1992 70:5-8.
30. Bird A, Tate P, Nan X, Campoy J, Meehan R, Cross S, et al.: Studies of DNA methylation in animals. J Cell Sci 1995, 19:37-39.
31. Leighton PA, Ingram RS, Eggenschwiler J, Efstratiadis A, Tilghman SM: Disruption of imprinting caused by deletion of the H19 gene region in mice. Nature 1995, 375:34-39.
32. Lin SY, Riggs AD: The general affinity of lac repressor for E. coli DNA: implication for gene regulation in procaryotes and eucaryotes. Cell 1975, 4:107-111.
33. Gottschling DE, Paracio OMA, Billington BL, Zakian VA: Position effect at S. cerevisiae telomeres: reversible repression of pol II transcription. Cell 1990, 63:751-752.
34. Moerle A, Paro R: Spreading the silence: epigenetic transcriptional regulation during Drosophila development. Dev Genet 1994, 15:478-484.
35. Carey M, Leatherwood J, Ptashne M: A potent Ga14 derivative activates transcription at a distance in vitro. Science 1990, 247:710-712.