메뉴 건너뛰기




Volumn 452, Issue 2, 2014, Pages 254-262

Genetic basis of rheumatoid arthritis: A current review

Author keywords

Anti citrullinated protein antibody; Genome wide association study; HLA DRB1; Rheumatoid arthritis

Indexed keywords

CHEMOKINE RECEPTOR CCR6; HLA DRB1 ANTIGEN; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 22; PAD14 PROTEIN; PROTEIN; STAT4 PROTEIN; TNFAIP3 PROTEIN; UNCLASSIFIED DRUG; CCR6 PROTEIN, HUMAN; DNA BINDING PROTEIN; HYDROLASE; NUCLEAR PROTEIN; PEPTIDYLARGININE DEIMINASE TYPE IV; PTPN22 PROTEIN, HUMAN; SIGNAL PEPTIDE; TNFAIP3 PROTEIN, HUMAN;

EID: 84908615900     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.07.085     Document Type: Review
Times cited : (46)

References (88)
  • 2
    • 0031974911 scopus 로고    scopus 로고
    • Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies
    • G.A. Schellekens, B.A. de Jong, F.H. van den Hoogen, L.B. van de Putte, W.J. van Venrooij, Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies, J. Clin. Invest. 101 (1998) 273-281.
    • (1998) J. Clin. Invest. , vol.101 , pp. 273-281
    • Schellekens, G.A.1    De Jong, B.A.2    Van Den Hoogen, F.H.3    Van De Putte, L.B.4    Van Venrooij, W.J.5
  • 3
    • 84886780720 scopus 로고    scopus 로고
    • Familial risks and heritability of rheumatoid arthritis: Role of rheumatoid factor/anti-citrullinated protein antibody status, number and type of affected relatives, sex, and age
    • T. Frisell, M. Holmqvist, H. Kallberg, L. Klareskog, L. Alfredsson, J. Askling, Familial risks and heritability of rheumatoid arthritis: role of rheumatoid factor/anti-citrullinated protein antibody status, number and type of affected relatives, sex, and age, Arthritis Rheum. 65 (2013) 2773-2782.
    • (2013) Arthritis Rheum. , vol.65 , pp. 2773-2782
    • Frisell, T.1    Holmqvist, M.2    Kallberg, H.3    Klareskog, L.4    Alfredsson, L.5    Askling, J.6
  • 7
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Project
    • International HapMap Consortium, The International HapMap Project, Nature 426 (2003) 789-796.
    • (2003) Nature , vol.426 , pp. 789-796
  • 8
    • 67650170347 scopus 로고    scopus 로고
    • Environmental influences on risk for rheumatoid arthritis
    • K.P. Liao, L. Alfredsson, E.W. Karlson, Environmental influences on risk for rheumatoid arthritis, Curr. Opin. Rheumatol. 21 (2009) 279-283.
    • (2009) Curr. Opin. Rheumatol. , vol.21 , pp. 279-283
    • Liao, K.P.1    Alfredsson, L.2    Karlson, E.W.3
  • 9
    • 80755128250 scopus 로고    scopus 로고
    • Environmental exposures and rheumatoid arthritis risk
    • R.A. Hoovestol, T.R. Mikuls, Environmental exposures and rheumatoid arthritis risk, Curr. Rheumatol. Rep. 13 (2011) 431-439.
    • (2011) Curr. Rheumatol. Rep. , vol.13 , pp. 431-439
    • Hoovestol, R.A.1    Mikuls, T.R.2
  • 10
    • 0014620885 scopus 로고
    • Altered reactivity in mixed lymphocyte culture of lymphocytes from patients with rheumatoid arthritis
    • G.P. Astorga, R.C. Williams Jr., Altered reactivity in mixed lymphocyte culture of lymphocytes from patients with rheumatoid arthritis, Arthritis Rheum. 12 (1969) 547-554.
    • (1969) Arthritis Rheum. , vol.12 , pp. 547-554
    • Astorga, G.P.1    Williams, R.C.2
  • 11
    • 0017506702 scopus 로고
    • Increased frequency of HLA-Cw3 and HLA-Dw4 in rheumatoid arthritis
    • A.J. McMichael, T. Sasazuki, H.O. McDevitt, R.O. Payne, Increased frequency of HLA-Cw3 and HLA-Dw4 in rheumatoid arthritis, Arthritis Rheum. 20 (1977) 1037-1042.
    • (1977) Arthritis Rheum. , vol.20 , pp. 1037-1042
    • McMichael, A.J.1    Sasazuki, T.2    McDevitt, H.O.3    Payne, R.O.4
  • 12
    • 0017878054 scopus 로고
    • Association of the B-cell alloantigen DRw4 with rheumatoid arthritis
    • P. Stastny, Association of the B-cell alloantigen DRw4 with rheumatoid arthritis, N. Engl. J. Med. 298 (1978) 869-871.
    • (1978) N. Engl. J. Med. , vol.298 , pp. 869-871
    • Stastny, P.1
  • 14
    • 0023500817 scopus 로고
    • The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
    • P.K. Gregersen, J. Silver, R.J. Winchester, The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis, Arthritis Rheum. 30 (1987) 1205-1213.
    • (1987) Arthritis Rheum. , vol.30 , pp. 1205-1213
    • Gregersen, P.K.1    Silver, J.2    Winchester, R.J.3
  • 15
    • 82455210404 scopus 로고    scopus 로고
    • Association of the HLA-DRB1 epitope LA(67, 74) with rheumatoid arthritis and citrullinated vimentin binding
    • B.M. Freed, R.P. Schuyler, M.T. Aubrey, Association of the HLA-DRB1 epitope LA(67, 74) with rheumatoid arthritis and citrullinated vimentin binding, Arthritis Rheum. 63 (2011) 3733-3739.
    • (2011) Arthritis Rheum. , vol.63 , pp. 3733-3739
    • Freed, B.M.1    Schuyler, R.P.2    Aubrey, M.T.3
  • 21
    • 0038107566 scopus 로고    scopus 로고
    • Cutting edge: The conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1∗0401 MHC class II molecule
    • J.A. Hill, S. Southwood, A. Sette, A.M. Jevnikar, D.A. Bell, E. Cairns, Cutting edge: the conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1∗0401 MHC class II molecule, J. Immunol. 171 (2003) 538-541.
    • (2003) J. Immunol. , vol.171 , pp. 538-541
    • Hill, J.A.1    Southwood, S.2    Sette, A.3    Jevnikar, A.M.4    Bell, D.A.5    Cairns, E.6
  • 35
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3000 shared controls
    • Wellcome Trust Case Control Consortium, Genome-wide association study of 14,000 cases of seven common diseases and 3000 shared controls, Nature 447 (2007) 661-678.
    • (2007) Nature , vol.447 , pp. 661-678
  • 47
  • 48
    • 77951976129 scopus 로고    scopus 로고
    • Ethnogenetic heterogeneity of rheumatoid arthritis-implications for pathogenesis
    • Y. Kochi, A. Suzuki, R. Yamada, K. Yamamoto, Ethnogenetic heterogeneity of rheumatoid arthritis-implications for pathogenesis, Nat. Rev. Rheumatol. 6 (2010) 290-295.
    • (2010) Nat. Rev. Rheumatol. , vol.6 , pp. 290-295
    • Kochi, Y.1    Suzuki, A.2    Yamada, R.3    Yamamoto, K.4
  • 51
    • 84870910115 scopus 로고    scopus 로고
    • Meta-analysis reveals an association of PTPN22 C1858T with autoimmune diseases, which depends on the localization of the affected tissue
    • J. Zheng, S. Ibrahim, F. Petersen, X. Yu, Meta-analysis reveals an association of PTPN22 C1858T with autoimmune diseases, which depends on the localization of the affected tissue, Genes Immun. 13 (2012) 641-652.
    • (2012) Genes Immun. , vol.13 , pp. 641-652
    • Zheng, J.1    Ibrahim, S.2    Petersen, F.3    Yu, X.4
  • 52
    • 21544436852 scopus 로고    scopus 로고
    • Ethnic differences in allele frequency of autoimmune-disease-associated SNPs
    • M. Mori, R. Yamada, K. Kobayashi, R. Kawaida, K. Yamamoto, Ethnic differences in allele frequency of autoimmune-disease-associated SNPs, J. Hum. Genet. 50 (2005) 264-266.
    • (2005) J. Hum. Genet. , vol.50 , pp. 264-266
    • Mori, M.1    Yamada, R.2    Kobayashi, K.3    Kawaida, R.4    Yamamoto, K.5
  • 53
    • 77952531776 scopus 로고    scopus 로고
    • Allele and haplotype frequency distribution in PTPN22 gene across variable ethnic groups: Implications for genetic association studies for autoimmune diseases
    • T.C. Lins, R.G. Vieira, D. Grattapaglia, R.W. Pereira, Allele and haplotype frequency distribution in PTPN22 gene across variable ethnic groups: Implications for genetic association studies for autoimmune diseases, Autoimmunity 43 (2010) 308-316.
    • (2010) Autoimmunity , vol.43 , pp. 308-316
    • Lins, T.C.1    Vieira, R.G.2    Grattapaglia, D.3    Pereira, R.W.4
  • 54
    • 65449176044 scopus 로고    scopus 로고
    • Cutting edge: The PTPN22 allelic variant associated with autoimmunity impairs B cell signaling
    • A.F. Arechiga, T. Habib, Y. He, X. Zhang, Z.Y. Zhang, A. Funk, J.H. Buckner, Cutting edge: the PTPN22 allelic variant associated with autoimmunity impairs B cell signaling, J. Immunol. 182 (2009) 3343-3347.
    • (2009) J. Immunol. , vol.182 , pp. 3343-3347
    • Arechiga, A.F.1    Habib, T.2    He, Y.3    Zhang, X.4    Zhang, Z.Y.5    Funk, A.6    Buckner, J.H.7
  • 58
    • 84891744142 scopus 로고    scopus 로고
    • The role of PTPN22 in autoimmunity: Learning from mice
    • J. Zheng, F. Petersen, X. Yu, The role of PTPN22 in autoimmunity: learning from mice, Autoimmun. Rev. 13 (2014) 266-271.
    • (2014) Autoimmun. Rev. , vol.13 , pp. 266-271
    • Zheng, J.1    Petersen, F.2    Yu, X.3
  • 65
    • 84879884295 scopus 로고    scopus 로고
    • Meta-analysis reveals an association of STAT4 polymorphisms with systemic autoimmune disorders and anti-dsDNA antibody
    • J. Zheng, J. Yin, R. Huang, F. Petersen, X. Yu, Meta-analysis reveals an association of STAT4 polymorphisms with systemic autoimmune disorders and anti-dsDNA antibody, Hum. Immunol. 74 (2013) 986-992.
    • (2013) Hum. Immunol. , vol.74 , pp. 986-992
    • Zheng, J.1    Yin, J.2    Huang, R.3    Petersen, F.4    Yu, X.5
  • 67
    • 59849096879 scopus 로고    scopus 로고
    • Cutting edge: Autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-alpha in lupus patients in vivo
    • S.N. Kariuki, K.A. Kirou, E.J. MacDermott, L. Barillas-Arias, M.K. Crow, T.B. Niewold, Cutting edge: autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-alpha in lupus patients in vivo, J. Immunol. 182 (2009) 34-38.
    • (2009) J. Immunol. , vol.182 , pp. 34-38
    • Kariuki, S.N.1    Kirou, K.A.2    MacDermott, E.J.3    Barillas-Arias, L.4    Crow, M.K.5    Niewold, T.B.6
  • 73
    • 13144265739 scopus 로고    scopus 로고
    • Genome-wide association studies: Theoretical and practical concerns
    • W.Y. Wang, B.J. Barratt, D.G. Clayton, J.A. Todd, Genome-wide association studies: theoretical and practical concerns, Nat. Rev. Genet. 6 (2005) 109-118.
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 109-118
    • Wang, W.Y.1    Barratt, B.J.2    Clayton, D.G.3    Todd, J.A.4
  • 77
    • 0028989782 scopus 로고
    • HLA-DRB1/0401/0404 genotype and rheumatoid arthritis: Increased association in men, young age at onset, and disease severity
    • A. MacGregor, W. Ollier, W. Thomson, D. Jawaheer, A. Silman, HLA-DRB1/0401/0404 genotype and rheumatoid arthritis: increased association in men, young age at onset, and disease severity, J. Rheumatol. 22 (1995) 1032-1036.
    • (1995) J. Rheumatol. , vol.22 , pp. 1032-1036
    • MacGregor, A.1    Ollier, W.2    Thomson, W.3    Jawaheer, D.4    Silman, A.5
  • 78
    • 0026447387 scopus 로고
    • The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritis
    • C.M. Weyand, K.C. Hicok, D.L. Conn, J.J. Goronzy, The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritis, Ann. Intern. Med. 117 (1992) 801-806.
    • (1992) Ann. Intern. Med. , vol.117 , pp. 801-806
    • Weyand, C.M.1    Hicok, K.C.2    Conn, D.L.3    Goronzy, J.J.4
  • 79
    • 84875985769 scopus 로고    scopus 로고
    • PADI4 and HLA-DRB1 are genetic risks for radiographic progression in RA patients, independent of ACPA status: Results from the IORRA cohort study
    • T. Suzuki, K. Ikari, K. Yano, E. Inoue, Y. Toyama, A. Taniguchi, H. Yamanaka, S. Momohara, PADI4 and HLA-DRB1 are genetic risks for radiographic progression in RA patients, independent of ACPA status: results from the IORRA cohort study, PLoS One 8 (2013) e61045.
    • (2013) PLoS One , vol.8 , pp. e61045
    • Suzuki, T.1    Ikari, K.2    Yano, K.3    Inoue, E.4    Toyama, Y.5    Taniguchi, A.6    Yamanaka, H.7    Momohara, S.8
  • 80
    • 23944519152 scopus 로고    scopus 로고
    • Investigation of polymorphisms in the PADI4 gene in determining severity of inflammatory polyarthritis
    • A. Barton, J. Bowes, S. Eyre, D. Symmons, J. Worthington, A. Silman, Investigation of polymorphisms in the PADI4 gene in determining severity of inflammatory polyarthritis, Ann. Rheum. Dis. 64 (2005) 1311-1315.
    • (2005) Ann. Rheum. Dis. , vol.64 , pp. 1311-1315
    • Barton, A.1    Bowes, J.2    Eyre, S.3    Symmons, D.4    Worthington, J.5    Silman, A.6
  • 81
    • 12344266544 scopus 로고    scopus 로고
    • Association between stromal cell-derived factor 1 chemokine gene variant and radiographic progression of rheumatoid arthritis
    • B. Joven, N. Gonzalez, F. Aguilar, B. Santiago, M. Galindo, J. Alcami, J.L. Pablos, Association between stromal cell-derived factor 1 chemokine gene variant and radiographic progression of rheumatoid arthritis, Arthritis Rheum. 52 (2005) 354-356.
    • (2005) Arthritis Rheum. , vol.52 , pp. 354-356
    • Joven, B.1    Gonzalez, N.2    Aguilar, F.3    Santiago, B.4    Galindo, M.5    Alcami, J.6    Pablos, J.L.7
  • 87
    • 79952442211 scopus 로고    scopus 로고
    • Genome-wide association study of genetic predictors of anti-tumor necrosis factor treatment efficacy in rheumatoid arthritis identifies associations with polymorphisms at seven loci
    • D. Plant, J. Bowes, C. Potter, K.L. Hyrich, A.W. Morgan, A.G. Wilson, J.D. Isaacs, Wellcome Trust Case Control Consortium, British Society for Rheumatology Biologics Register, A. Barton, Genome-wide association study of genetic predictors of anti-tumor necrosis factor treatment efficacy in rheumatoid arthritis identifies associations with polymorphisms at seven loci, Arthritis Rheum. 63 (2011) 645-653.
    • Arthritis Rheum._rfpy1 2011 , vol.63 , pp. 645-653
    • Plant, D.1    Bowes, J.2    Potter, C.3    Hyrich, K.L.4    Morgan, A.W.5    Wilson, A.G.6    Isaacs, J.D.7    Barton, A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.