Cutting edge: Autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-α in lupus patients in vivo

Journal of Immunology

Volumn 182, Issue 1, 2009, Pages 34-38

  Kariuki, Silvia N ^a   Kirou, Kyriakos A ^b   MacDermott, Emma J ^b   Barillas Arias, Lilliana ^b   Crow, Mary K ^b   Niewold, Timothy B ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; INTERFERON REGULATORY FACTOR 5; STAT4 PROTEIN; INTERFERON REGULATORY FACTOR; IRF5 PROTEIN, HUMAN; STAT4 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE FREQUENCY; GENETIC RISK; GENETIC VARIABILITY; HUMAN; IN VIVO STUDY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; ALLELE; BLOOD; CELL LINE; DOWN REGULATION; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; HAPLOTYPE; IMMUNOLOGY; PHYSIOLOGY; RISK FACTOR;

ALLELES; CELL LINE; DOWN-REGULATION; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HAPLOTYPES; HUMANS; INTERFERON REGULATORY FACTORS; INTERFERON-ALPHA; LUPUS ERYTHEMATOSUS, SYSTEMIC; RISK FACTORS; SIGNAL TRANSDUCTION; STAT4 TRANSCRIPTION FACTOR;

EID: 59849096879     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.182.1.34     Document Type: Article

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