Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity

American Journal of Human Genetics

Volumn 94, Issue 4, 2014, Pages 522-532

  Han, Buhm ^a,b,c   Diogo, Dorothée ^a,b,c   Eyre, Steve ^d,e   Kallberg, Henrik ^f   Zhernakova, Alexandra ^g,h   Bowes, John ^d,e   Padyukov, Leonid ^f   Okada, Yukinori ^a,b,c   González Gay, Miguel A ⁱ   Rantapää Dahlqvist, Solbritt ^j   Martin, Javier ^k   Huizinga, Tom W J ^g   Plenge, Robert M ^l   Worthington, Jane ^d,e   Gregersen, Peter K ^m   Klareskog, Lars ^f   De Bakker, Paul I W ^a,b,n   Raychaudhuri, Soumya ^a,b,c,d  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c LABORATORY FOR MOLECULAR MEDICINE   (United States)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^f KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^g LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^h UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

ⁱ HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

^j UMEÅ UNIVERSITY   (Sweden)

^k INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^l MERCK RESEARCH LABORATORIES   (United States)

^m Merck Research Laboratories Merck and Co Inc ^*  (United States)

ⁿ UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

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Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ASPARTIC ACID; LEUCINE; SERINE;

ALLELE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; EFFECT SIZE; GENE MAPPING; GENETIC HETEROGENEITY; HLA SYSTEM; HUMAN; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; PHENOTYPE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; ARTHRITIS, RHEUMATOID; CASE-CONTROL STUDIES; GENETIC HETEROGENEITY; HLA ANTIGENS; HUMANS;

EID: 84897992288     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2014.02.013     Document Type: Article

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