Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

Nature Genetics

Volumn 44, Issue 12, 2012, Pages 1341-1348

  Tsoi, Lam C ^a,ap   Spain, Sarah L ^b,ap   Knight, Jo ^c,d,ap   Ellinghaus, Eva ^e,ap   Stuart, Philip E ^f   Capon, Francesca ^b   Ding, Jun ^a   Li, Yun ^a   Tejasvi, Trilokraj ^f   Gudjonsson, Johann E ^f   Kang, Hyun M ^a   Allen, Michael H ^b   McManus, Ross ^g,h   Novelli, Giuseppe ^i,j   Samuelsson, Lena ^k   Schalkwijk, Joost ^l   Ståhle, Mona ^m   Burden, A David ⁿ   Smith, Catherine H ^b   Cork, Michael J ^o   Estivill, Xavier ^p   Bowcock, Anne M ^q   Krueger, Gerald G ^r   Weger, Wolfgang ^s   Worthington, Jane ^t   Tazi Ahnini, Rachid ^o   Nestle, Frank O ^b   Hayday, Adrian ^b   Hoffmann, Per ^u   Winkelmann, Juliane ^v,w   Wijmenga, Cisca ^x   Langford, Cordelia ^y   Edkins, Sarah ^y   Andrews, Robert ^y   Blackburn, Hannah ^y   Strange, Amy ^z   Band, Gavin ^z   Pearson, Richard D ^z   Vukcevic, Damjan ^z   Spencer, Chris C A ^z   Deloukas, Panos ^y   Mrowietz, Ulrich ^aa   Schreiber, Stefan ^e,aa   Weidinger, Stephan ^aa   Koks, Sulev ^ab   Kingo, Külli ^ac   Esko, Tonu ^ad   Metspalu, Andres ^ad   Lim, Henry W ^ae   Voorhees, John J ^f   Weichenthal, Michael ^aa   Wichmann, H Erich ^w,af,ag   Chandran, Vinod ^ah   Rosen, Cheryl F ^ah   Rahman, Proton ^ai   Gladman, Dafna D ^ah   Griffiths, Christopher E M ^t   Reis, Andre ^aj   Kere, Juha ^m,ak,al   Nnair, Rajan P ^f   Franke, Andre ^e,y   Barker, Jonathan N W N ^y   Abecasis, Goncalo R ^y   Eelder, James Tt ^f,am   Ttrembath, Richard ^b,an   Duffin, Kristina Callis ^r   Helms, Cindy ^q   Goldgar, David ^r   Paschall, Justin ^ao,ap   Malloy, Mary J ^q,ap   Pullinger, Clive R ^q,ap   Kane, John P ^q,ap   Gardner, Jennifer ^q   Perlmutter, Amy ^aq   Miner, Andrew ^aq   Feng, Bing Jian ^r   Hiremagalore, Ravi ^f   Ike, Robert W ^ar   Christophers, Enno ^aa   Henseler, Tilo ^aa   Ruether, Andreas ^e   Schrodi, Steven J ^r   Prahalad, Sampath ^as,at   Guthery, Stephen L ^as,at   Fischer, Judith ^au   Liao, Wilson ^av   Kwok, Pui ^av   Menter, Alan ^aw   Lathrop, G Mark ^au   Wise, C ^al   Begovich, Ann B ^r   Onoufriadis, Alexandros ^b   Weale, Michael E ^b   Hofer, Angelika ^s   Salmhofer, Wolfgang ^s   Wolf, Peter ^s   Kainu, Kati ^ax   Saarialho Kere, Ulpu ^ax   Suomela, Sari ^ax   Badorf, Petra ^aj   Hüffmeier, Ulrike ^aj   Kurrat, Werner ^ay   Küster, Wolfgang ^az   Lascorz, Jesús ^ba   Mössner, Rotraut ^bb   Schürmeier Horst, Funda ^bc   Ständer, Markward ^l   Traupe, Heiko ^bc   Bergboer, Judith G M ^l   Heijer, Martin Den ^l,bd   Van De Kerkhof, Peter C ^l   Zeeuwen, Patrick L J M ^l   Barnes, Louise ^g,h   Campbell, Linda E ^be   Cusack, Caitriona ^bf   Coleman, Ciara ^g,h   Conroy, Judith ^g,h   Ennis, Sean ^g,h   Fitzgerald, Oliver ^bg   Gallagher, Phil ^bg   Irvine, Alan D ^bh   Kirby, Brian ^bg   Markham, Trevor ^bf   McLean, W H Irwin ^be   McPartlin, Joe ^g,h   Rogers, Sarah F ^bg   Ryan, Anthony W ^g,h   Zawirska, Agnieszka ^bg   Giardina, Emiliano ⁱ   Lepre, Tiziana ⁱ   Perricone, Carlo ⁱ   Martín Ezquerra, Gemma ^bi   Pujol, Ramon M ^bi   Riveira Munoz, Eva ^p   Inerot, Annica ^bj   Naluai, Åsa T ^k   Mallbris, Lotus ^m   Wolk, Katarina ^m   Leman, Joyce ⁿ   Barton, Anne ^t   Warren, Richard B ^t   Young, Helen S ^t   Ricano Ponce, Isis ^x   Trynka, Gosia ^x   Pellett, Fawnda J ^ah   Henschel, Andrew ^w   Aurand, Marin ^w   Bebo, Bruce ^w   Gieger, Christian ^w   Illig, Thomas ^bk   Moebus, Susanne ^bl   Jöckel, Karl Heinz ^bl   Erbel, Raimund ^bm   Donnelly, Peter ^z,bn   Peltonen, Leena ^y   Blackwell, Jenefer M ^b,bo   Bramon, Elvira ^bp,bq   Brown, Matthew A ^br   Casas, Juan P ^h   Corvin, Aiden ^bs   Craddock, Nicholas ^bt   Duncanson, Audrey ^an   Jankowski, Janusz ^bu   Markus, Hugh S ^bv   Mathew, Christopher G ^b   McCarthy, Mark I ^bw   Palmer, Colin N A ^b   Plomin, Robert ^bx   Rautanen, Anna ^z   Sawcer, Stephen J ^by   Samani, Nilesh ^bz   Viswanathan, Ananth C ^ca,cb   Wood, Nicholas W ^cb   Bellenguez, Céline ^z   Freeman, Colin ^z   Hellenthal, Garrett ^z   Giannoulatou, Eleni ^z   Pirinen, Matti ^z   Su, Zhan ^z   Hunt, Sarah E ^y   Gwilliam, Rhian ^y   Bumpstead, Suzannah J ^y   Dronov, Serge ^y   Gillman, Matthew ^y   Gray, Emma ^y   Hammond, Naomi ^y   Jayakumar, Alagurevathi ^y   McCann, Owen T ^y   Liddle, Jennifer ^y   Perez, Marc L ^y   Potter, Simon C ^y   Ravindrarajah, Radhi ^y   Ricketts, Michelle ^y   Waller, Matthew ^y   Weston, Paul ^y   Widaa, Sara ^y   Whittaker, Pamela ^y   Neir, Rajan P ^y   Elder, James T ^y   Trembath, Richard C ^y   more..

^a UNIVERSITY OF MICHIGAN   (United States)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^d GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

^e UNIVERSITY OF KIEL   (Germany)

^f UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^g ST JAMES S HOSPITAL   (Ireland)

^h TRINITY COLLEGE DUBLIN   (Ireland)

ⁱ Responsable for National Scientific Habilitation   (Italy)

^j FATEBENEFRATELLI HOSPITAL   (Italy)

^k UNIVERSITY OF GOTHENBURG   (Sweden)

^l RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^m KAROLINSKA INSTITUTE   (Sweden)

ⁿ WESTERN INFIRMARY   (United Kingdom)

^o UNIVERSITY OF SHEFFIELD   (United Kingdom)

^p CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^q WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^r UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^s MEDICAL UNIVERSITY OF GRAZ   (Austria)

^t UNIVERSITY OF MANCHESTER   (United Kingdom)

^u UNIVERSITY OF BONN   (Germany)

^v TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^w INSTITUTE OF EPIDEMIOLOGY   (Germany)

^x UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^y WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^z UNIVERSITY OF OXFORD   (United Kingdom)

^aa UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^ab Faculty of Medicine   (Estonia)

^ac UNIVERSITY OF TARTU   (Estonia)

^ad UNIVERSITY OF TARTU   (Estonia)

^ae HENRY FORD HOSPITAL   (United States)

^af UNIVERSITY OF MUNICH   (Germany)

^ag LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^ah UNIVERSITY OF TORONTO   (Canada)

^ai MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

^aj UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^ak FOLKHÄLSAN INSTITUTE OF GENETICS   (Finland)

^al UNIVERSITY OF HELSINKI   (Finland)

^am VETERANS AFFAIRS MEDICAL CENTER   (United States)

^an QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^ao NATIONAL INSTITUTES OF HEALTH   (United States)

^ap UNIVERSITY OF CALIFORNIA   (United States)

^aq UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^ar CELERA   (United States)

^as UNIVERSITY OF UTAH   (United States)

^at CENTRE NATIONAL DE GÉNOTYPAGE   (France)

^au UNIVERSITY OF CALIFORNIA   (United States)

^av BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

^aw TEXAS SCOTTISH RITE HOSPITAL FOR CHILDREN   (United States)

^ax Rehabilitationskllnik F A   (Germany)

^ay TOMESA Clinics   (Germany)

^az GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^ba UNIVERSITY OF GÖTTINGEN   (Germany)

^bb UNIVERSITY OF MÜNSTER   (Germany)

^bc Psoriasis Rehabilitation Hospital   (Germany)

^bd UNIVERSITY OF DUNDEE   (United Kingdom)

^be UNIVERSITY HOSPITAL GALWAY   (Ireland)

^bf ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^bg OUR LADY S CHILDREN S HOSPITAL   (Ireland)

^bh HOSPITAL DEL MAR   (Spain)

^bi SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^bj National Psoriasis Foundation   (United States)

^bk UNIVERSITY OF DUISBURG ESSEN   (Germany)

^bl UNIVERSITY HOSPITAL ESSEN   (Germany)

^bm UNIVERSITY OF OXFORD   (United Kingdom)

^bn UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^bo ADDENBROOKE S HOSPITAL   (United Kingdom)

^bp SOUTH LONDON AND MAUDSLEY NHS FOUNDATION TRUST   (United Kingdom)

^bq UNIVERSITY OF QUEENSLAND   (Australia)

^br LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^bs CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

^bt WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^bu ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^bv CHURCHILL HOSPITAL   (United Kingdom)

^bw UNIVERSITY OF DUNDEE   (United Kingdom)

^bx UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^by UNIVERSITY OF LEICESTER   (United Kingdom)

^bz MOORFIELDS EYE HOSPITAL   (United Kingdom)

^ca UNIVERSITY COLLEGE LONDON   (United Kingdom)

^cb UNIVERSITY COLLEGE LONDON   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; DNA DIRECTED DNA POLYMERASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METHYL CPG BINDING PROTEIN 2; RETINOIC ACID INDUCIBLE PROTEIN I; STAT3 PROTEIN; TRANSCRIPTION FACTOR RUNX3;

ARTICLE; CONTROLLED STUDY; EUROPE; GENE IDENTIFICATION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HOST RESISTANCE; HUMAN; HUMAN CELL; INNATE IMMUNITY; MACROPHAGE ACTIVATION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PSORIASIS;

EID: 84870512735     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2467     Document Type: Article

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