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Volumn 13, Issue 8, 2012, Pages 641-652

Meta-analysis reveals an association of PTPN22 C1858T with autoimmune diseases, which depends on the localization of the affected tissue

Author keywords

association; autoimmune diseases; meta analysis; protein tyrosine phosphatase non receptor type 22; susceptibility gene; target tissue

Indexed keywords

CYTOSINE; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 22; THYMINE;

EID: 84870910115     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/gene.2012.46     Document Type: Article
Times cited : (92)

References (144)
  • 2
    • 12144291502 scopus 로고    scopus 로고
    • A functional variant of lymphoid tyrosine phosphatase is associated with type i diabetes
    • Bottini N, Musumeci L, Alonso A, Rahmouni S, Nika K, Rostamkhani M et al. A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet 2004; 36: 337-338.
    • (2004) Nat Genet , vol.36 , pp. 337-338
    • Bottini, N.1    Musumeci, L.2    Alonso, A.3    Rahmouni, S.4    Nika, K.5    Rostamkhani, M.6
  • 3
    • 3242713277 scopus 로고    scopus 로고
    • A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
    • Begovich AB, Carlton VE, Honigberg LA, Schrodi SJ, Chokkalingam AP, Alexander HC et al. A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet 2004; 75: 330-337.
    • (2004) Am J Hum Genet , vol.75 , pp. 330-337
    • Begovich, A.B.1    Carlton, V.E.2    Honigberg, L.A.3    Schrodi, S.J.4    Chokkalingam, A.P.5    Alexander, H.C.6
  • 4
    • 4143105691 scopus 로고    scopus 로고
    • Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE
    • Kyogoku C, Langefeld CD, Ortmann WA, Lee A, Selby S, Carlton VE et al. Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. Am J Hum Genet 2004; 75: 504-507.
    • (2004) Am J Hum Genet , vol.75 , pp. 504-507
    • Kyogoku, C.1    Langefeld, C.D.2    Ortmann, W.A.3    Lee, A.4    Selby, S.5    Carlton, V.E.6
  • 5
    • 7044253358 scopus 로고    scopus 로고
    • Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus
    • Smyth D, Cooper JD, Collins JE, Heward JM, Franklyn JA, Howson JM et al. Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus. Diabetes 2004; 53: 3020-3023.
    • (2004) Diabetes , vol.53 , pp. 3020-3023
    • Smyth, D.1    Cooper, J.D.2    Collins, J.E.3    Heward, J.M.4    Franklyn, J.A.5    Howson, J.M.6
  • 6
    • 0033559313 scopus 로고    scopus 로고
    • Cloning and characterization of a lymphoid-specific, inducible human protein tyrosine phosphatase, Lyp
    • Cohen S, Dadi H, Shaoul E, Sharfe N, Roifman CM. Cloning and characterization of a lymphoid-specific, inducible human protein tyrosine phosphatase, Lyp. Blood 1999; 93: 2013-2024.
    • (1999) Blood , vol.93 , pp. 2013-2024
    • Cohen, S.1    Dadi, H.2    Shaoul, E.3    Sharfe, N.4    Roifman, C.M.5
  • 7
    • 28444469783 scopus 로고    scopus 로고
    • Autoimmuneassociated lymphoid tyrosine phosphatase is a gain-of-function variant
    • Vang T, Congia M, Macis MD, Musumeci L, Orru V, Zavattari P et al. Autoimmuneassociated lymphoid tyrosine phosphatase is a gain-of-function variant. Nat Genet 2005; 37: 1317-1319.
    • (2005) Nat Genet , vol.37 , pp. 1317-1319
    • Vang, T.1    Congia, M.2    MacIs, M.D.3    Musumeci, L.4    Orru, V.5    Zavattari, P.6
  • 8
    • 65449176044 scopus 로고    scopus 로고
    • Cutting edge: The PTPN22 allelic variant associated with autoimmunity impairs B cell signaling
    • Arechiga AF, Habib T, He Y, Zhang X, Zhang ZY, Funk A et al. Cutting edge: the PTPN22 allelic variant associated with autoimmunity impairs B cell signaling. J Immunol 2009; 182: 3343-3347.
    • (2009) J Immunol , vol.182 , pp. 3343-3347
    • Arechiga, A.F.1    Habib, T.2    He, Y.3    Zhang, X.4    Zhang, Z.Y.5    Funk, A.6
  • 9
    • 77956305092 scopus 로고    scopus 로고
    • PTPN22 gene regulates natural killer cell proliferation during in vitro expansion
    • Douroudis K, Shcherbakova A, Everaus H, Aints A. PTPN22 gene regulates natural killer cell proliferation during in vitro expansion. Tissue Antigens 2010; 76: 315-318.
    • (2010) Tissue Antigens , vol.76 , pp. 315-318
    • Douroudis, K.1    Shcherbakova, A.2    Everaus, H.3    Aints, A.4
  • 10
    • 0942279640 scopus 로고    scopus 로고
    • PEST domainenriched tyrosine phosphatase (PEP) regulation of effector/memory T cells
    • Hasegawa K, Martin F, Huang G, Tumas D, Diehl L, Chan AC. PEST domainenriched tyrosine phosphatase (PEP) regulation of effector/memory T cells. Science 2004; 303: 685-689.
    • (2004) Science , vol.303 , pp. 685-689
    • Hasegawa, K.1    Martin, F.2    Huang, G.3    Tumas, D.4    Diehl, L.5    Chan, A.C.6
  • 11
  • 12
    • 26044482775 scopus 로고    scopus 로고
    • The functional genetic variation in the PTPN22 gene has a negligible effect on the susceptibility to develop inflammatory bowel disease
    • Martin MC, Oliver J, Urcelay E, Orozco G, Gomez-Garcia M, Lopez-Nevot MA et al. The functional genetic variation in the PTPN22 gene has a negligible effect on the susceptibility to develop inflammatory bowel disease. Tissue Antigens 2005; 66: 314-317.
    • (2005) Tissue Antigens , vol.66 , pp. 314-317
    • Martin, M.C.1    Oliver, J.2    Urcelay, E.3    Orozco, G.4    Gomez-Garcia, M.5    Lopez-Nevot, M.A.6
  • 13
    • 33745168780 scopus 로고    scopus 로고
    • Lack of association between the protein tyrosine phosphatase non-receptor 22 (PTPN22)*620W allele and systemic sclerosis in the French Caucasian population
    • Wipff J, Allanore Y, Kahan A, Meyer O, Mouthon L, Guillevin L et al. Lack of association between the protein tyrosine phosphatase non-receptor 22 (PTPN22)*620W allele and systemic sclerosis in the French Caucasian population. Ann Rheum Dis 2006; 65: 1230-1232.
    • (2006) Ann Rheum Dis , vol.65 , pp. 1230-1232
    • Wipff, J.1    Allanore, Y.2    Kahan, A.3    Meyer, O.4    Mouthon, L.5    Guillevin, L.6
  • 14
    • 80052098376 scopus 로고    scopus 로고
    • Association of PTPN22 1858T/T genotype with type 1 diabetes Graves' disease but not with rheumatoid arthritis in Russian population
    • (Albany NY)
    • Zhebrun D, Kudryashova Y, Babenko A, Maslyansky A, Kunitskaya N, Popcova D et al. Association of PTPN22 1858T/T genotype with type 1 diabetes, Graves' disease but not with rheumatoid arthritis in Russian population. Aging (Albany NY) 2011; 3: 368-373.
    • (2011) Aging , vol.3 , pp. 368-373
    • Zhebrun, D.1    Kudryashova, Y.2    Babenko, A.3    Maslyansky, A.4    Kunitskaya, N.5    Popcova, D.6
  • 15
    • 28544444239 scopus 로고    scopus 로고
    • Finnish case-control and family studies support PTPN22 R620W polymorphism as a risk factor in rheumatoid arthritis, but suggest only minimal or no effect in juvenile idiopathic arthritis
    • Seldin MF, Shigeta R, Laiho K, Li H, Saila H, Savolainen A et al. Finnish case-control and family studies support PTPN22 R620W polymorphism as a risk factor in rheumatoid arthritis, but suggest only minimal or no effect in juvenile idiopathic arthritis. Genes Immun 2005; 6: 720-722.
    • (2005) Genes Immun , vol.6 , pp. 720-722
    • Seldin, M.F.1    Shigeta, R.2    Laiho, K.3    Li, H.4    Saila, H.5    Savolainen, A.6
  • 17
    • 54049090387 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase non-receptor type 22 gene variants at position 1858 are associated with type 1 and type 2 diabetes in Estonian population
    • Douroudis K, Prans E, Haller K, Nemvalts V, Rajasalu T, Tillmann V et al. Protein tyrosine phosphatase non-receptor type 22 gene variants at position 1858 are associated with type 1 and type 2 diabetes in Estonian population. Tissue Antigens 2008; 72: 425-430.
    • (2008) Tissue Antigens , vol.72 , pp. 425-430
    • Douroudis, K.1    Prans, E.2    Haller, K.3    Nemvalts, V.4    Rajasalu, T.5    Tillmann, V.6
  • 18
    • 34848836690 scopus 로고    scopus 로고
    • Association of PTPN22 single nucleotide polymorphism with rheumatoid arthritis but not with allergic asthma
    • Majorczyk E, Jasek M, Ploski R, Wagner M, Kosior A, Pawlik A et al. Association of PTPN22 single nucleotide polymorphism with rheumatoid arthritis but not with allergic asthma. Eur J Hum Genet 2007; 15: 1043-1048.
    • (2007) Eur J Hum Genet , vol.15 , pp. 1043-1048
    • Majorczyk, E.1    Jasek, M.2    Ploski, R.3    Wagner, M.4    Kosior, A.5    Pawlik, A.6
  • 19
    • 61849113299 scopus 로고    scopus 로고
    • PTPN22/LYP 1858C4T gene polymorphism and susceptibility to endometriosis in a Polish population
    • Ploski R, Dziunycz P, Kostrzewa G, Roszkowski PI, Barcz E, Zabek J et al. PTPN22/LYP 1858C4T gene polymorphism and susceptibility to endometriosis in a Polish population. J Reprod Immunol 2009; 79: 196-200.
    • (2009) J Reprod Immunol , vol.79 , pp. 196-200
    • Ploski, R.1    Dziunycz, P.2    Kostrzewa, G.3    Roszkowski, P.I.4    Barcz, E.5    Zabek, J.6
  • 20
    • 20444474163 scopus 로고    scopus 로고
    • Lymphoid tyrosine phosphatase (PTPN22/LYP) variant and Graves' disease in a polish population: Association and gene dose-dependent correlation with age of onset
    • Skorka A, Bednarczuk T, Bar-Andziak E, Nauman J, Ploski R. Lymphoid tyrosine phosphatase (PTPN22/LYP) variant and Graves' disease in a polish population: association and gene dose-dependent correlation with age of onset. Clin Endocrinol (Oxford) 2005; 62: 679-682.
    • (2005) Clin Endocrinol (Oxford) , vol.62 , pp. 679-682
    • Skorka, A.1    Bednarczuk, T.2    Bar-Andziak, E.3    Nauman, J.4    Ploski, R.5
  • 22
    • 34447273288 scopus 로고    scopus 로고
    • The PTPN22 1858C/T polymorphism is associated with anti-cyclic citrullinated peptide antibody-positive early rheumatoid arthritis in northern Sweden
    • Kokkonen H, Johansson M, Innala L, Jidell E, Rantapaa-Dahlqvist S. The PTPN22 1858C/T polymorphism is associated with anti-cyclic citrullinated peptide antibody-positive early rheumatoid arthritis in northern Sweden. Arthritis Res Ther 2007; 9: R56.
    • (2007) Arthritis Res Ther , vol.9
    • Kokkonen, H.1    Johansson, M.2    Innala, L.3    Jidell, E.4    Rantapaa-Dahlqvist, S.5
  • 23
    • 46649095805 scopus 로고    scopus 로고
    • PTPN22 R620W promotes production of anti-AChR autoantibodies and IL-2 in myasthenia gravis
    • Lefvert AK, Zhao Y, Ramanujam R, Yu S, Pirskanen R, Hammarstrom L. PTPN22 R620W promotes production of anti-AChR autoantibodies and IL-2 in myasthenia gravis. J Neuroimmunol 2008; 197: 110-113.
    • (2008) J Neuroimmunol , vol.197 , pp. 110-113
    • Lefvert, A.K.1    Zhao, Y.2    Ramanujam, R.3    Yu, S.4    Pirskanen, R.5    Hammarstrom, L.6
  • 26
    • 34547131553 scopus 로고    scopus 로고
    • The PTPN22 promoter polymorphism-1123G4C association cannot be distinguished from the 1858C4T association in a Norwegian rheumatoid arthritis material
    • Viken MK, Olsson M, Flam ST, Forre O, Kvien TK, Thorsby E et al. The PTPN22 promoter polymorphism-1123G4C association cannot be distinguished from the 1858C4T association in a Norwegian rheumatoid arthritis material. Tissue Antigens 2007; 70: 190-197.
    • (2007) Tissue Antigens , vol.70 , pp. 190-197
    • Viken, M.K.1    Olsson, M.2    Flam, S.T.3    Forre, O.4    Kvien, T.K.5    Thorsby, E.6
  • 27
    • 38349150040 scopus 로고    scopus 로고
    • The R620W polymorphism in PTPN22 confers general susceptibility for the development of alopecia areata
    • Betz RC, Konig K, Flaquer A, Redler S, Eigelshoven S, Kortum AK et al. The R620W polymorphism in PTPN22 confers general susceptibility for the development of alopecia areata. Br J Dermatol 2008; 158: 389-391.
    • (2008) Br J Dermatol , vol.158 , pp. 389-391
    • Betz, R.C.1    Konig, K.2    Flaquer, A.3    Redler, S.4    Eigelshoven, S.5    Kortum, A.K.6
  • 28
    • 70449491816 scopus 로고    scopus 로고
    • Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: Higher frequency of the risk allele in male compared to female patients
    • Pierer M, Kaltenhauser S, Arnold S, Wahle M, Baerwald C, Hantzschel H et al. Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients. Arthritis Res Ther 2006; 8: R75.
    • (2006) Arthritis Res Ther , vol.8
    • Pierer, M.1    Kaltenhauser, S.2    Arnold, S.3    Wahle, M.4    Baerwald, C.5    Hantzschel, H.6
  • 29
    • 25844509213 scopus 로고    scopus 로고
    • A case-control study of tyrosine phosphatase (PTPN22) confirms the lack of association with Crohn's disease
    • Wagenleiter SE, Klein W, Griga T, Schmiegel W, Epplen JT, Jagiello P. A case-control study of tyrosine phosphatase (PTPN22) confirms the lack of association with Crohn's disease. Int J Immunogenet 2005; 32: 323-324.
    • (2005) Int J Immunogenet , vol.32 , pp. 323-324
    • Wagenleiter, S.E.1    Klein, W.2    Griga, T.3    Schmiegel, W.4    Epplen, J.T.5    Jagiello, P.6
  • 30
    • 33947185660 scopus 로고    scopus 로고
    • No independent role of the-1123 G4C and\+2740 A4G variants in the association of PTPN22 with type 1 diabetes and juvenile idiopathic arthritis in two Caucasian populations
    • Cinek O, Hradsky O, Ahmedov G, Slavcev A, Kolouskova S, Kulich M et al. No independent role of the-1123 G4C and\+2740 A4G variants in the association of PTPN22 with type 1 diabetes and juvenile idiopathic arthritis in two Caucasian populations. Diabetes Res Clin Pract 2007; 76: 297-303.
    • (2007) Diabetes Res Clin Pract , vol.76 , pp. 297-303
    • Cinek, O.1    Hradsky, O.2    Ahmedov, G.3    Slavcev, A.4    Kolouskova, S.5    Kulich, M.6
  • 31
    • 43849100606 scopus 로고    scopus 로고
    • Variants of CARD15 TNFA and PTPN22 and susceptibility to Crohn's disease in the Czech population: High frequency of the CARD15 1007fs
    • Hradsky O, Lenicek M, Dusatkova P, Bronsky J, Nevoral J, Valtrova V et al. Variants of CARD15, TNFA and PTPN22 and susceptibility to Crohn's disease in the Czech population: high frequency of the CARD15 1007fs. Tissue Antigens 2008; 71: 538-547.
    • (2008) Tissue Antigens , vol.71 , pp. 538-547
    • Hradsky, O.1    Lenicek, M.2    Dusatkova, P.3    Bronsky, J.4    Nevoral, J.5    Valtrova, V.6
  • 32
    • 67650742214 scopus 로고    scopus 로고
    • Association of common polymorphisms in known susceptibility genes with rheumatoid arthritis in a Slovak population using osteoarthritis patients as controls
    • Stark K, Rovensky J, Blazickova S, Grosse-Wilde H, Ferencik S, Hengstenberg C et al. Association of common polymorphisms in known susceptibility genes with rheumatoid arthritis in a Slovak population using osteoarthritis patients as controls. Arthritis Res Ther 2009; 11: R70.
    • (2009) Arthritis Res Ther , vol.11
    • Stark, K.1    Rovensky, J.2    Blazickova, S.3    Grosse-Wilde, H.4    Ferencik, S.5    Hengstenberg, C.6
  • 33
    • 36249026188 scopus 로고    scopus 로고
    • Sex-specific association of the human PTPN22 1858T-allele with type 1 diabetes
    • Nielsen C, Hansen D, Husby S, Lillevang ST. Sex-specific association of the human PTPN22 1858T-allele with type 1 diabetes. Int J Immunogenet 2007; 34: 469-473.
    • (2007) Int J Immunogenet , vol.34 , pp. 469-473
    • Nielsen, C.1    Hansen, D.2    Husby, S.3    Lillevang, S.T.4
  • 34
    • 27844531635 scopus 로고    scopus 로고
    • A single-nucleotide polymorphism in the gene encoding lymphoid protein tyrosine phosphatase (PTPN22) confers susceptibility to generalised vitiligo
    • Canton I, Akhtar S, Gavalas NG, Gawkrodger DJ, Blomhoff A, Watson PF et al. A single-nucleotide polymorphism in the gene encoding lymphoid protein tyrosine phosphatase (PTPN22) confers susceptibility to generalised vitiligo. Genes Immun 2005; 6: 584-587.
    • (2005) Genes Immun , vol.6 , pp. 584-587
    • Canton, I.1    Akhtar, S.2    Gavalas, N.G.3    Gawkrodger, D.J.4    Blomhoff, A.5    Watson, P.F.6
  • 35
    • 34248184607 scopus 로고    scopus 로고
    • Investigation of genetic variation across the protein tyrosine phosphatase gene in patients with rheumatoid arthritis in the UK
    • Hinks A, Eyre S, Barton A, Thomson W, Worthington J. Investigation of genetic variation across the protein tyrosine phosphatase gene in patients with rheumatoid arthritis in the UK. Ann Rheum Dis 2007; 66: 683-686.
    • (2007) Ann Rheum Dis , vol.66 , pp. 683-686
    • Hinks, A.1    Eyre, S.2    Barton, A.3    Thomson, W.4    Worthington, J.5
  • 36
    • 33745608045 scopus 로고    scopus 로고
    • The non-synonymous C1858T substitution in the PTPN22 gene is associated with susceptibility to the severe forms of alopecia areata
    • Kemp EH, McDonagh AJ, Wengraf DA, Messenger AG, Gawkrodger DJ, Cork MJ et al. The non-synonymous C1858T substitution in the PTPN22 gene is associated with susceptibility to the severe forms of alopecia areata. Hum Immunol 2006; 67: 535-539.
    • (2006) Hum Immunol , vol.67 , pp. 535-539
    • Kemp, E.H.1    McDonagh, A.J.2    Wengraf, D.A.3    Messenger, A.G.4    Gawkrodger, D.J.5    Cork, M.J.6
  • 37
    • 26044441694 scopus 로고    scopus 로고
    • A general autoimmunity gene (PTPN22) is not associated with inflammatory bowel disease in a British population
    • Prescott NJ, Fisher SA, Onnie C, Pattni R, Steer S, Sanderson J et al. A general autoimmunity gene (PTPN22) is not associated with inflammatory bowel disease in a British population. Tissue Antigens 2005; 66: 318-320.
    • (2005) Tissue Antigens , vol.66 , pp. 318-320
    • Prescott, N.J.1    Fisher, S.A.2    Onnie, C.3    Pattni, R.4    Steer, S.5    Sanderson, J.6
  • 39
    • 12344257537 scopus 로고    scopus 로고
    • Association of R602W in a protein tyrosine phosphatase gene with a high risk of rheumatoid arthritis in a British population: Evidence for an early onset/disease severity effect
    • Steer S, Lad B, Grumley JA, Kingsley GH, Fisher SA. Association of R602W in a protein tyrosine phosphatase gene with a high risk of rheumatoid arthritis in a British population: evidence for an early onset/disease severity effect. Arthritis Rheum 2005; 52: 358-360.
    • (2005) Arthritis Rheum , vol.52 , pp. 358-360
    • Steer, S.1    Lad, B.2    Grumley, J.A.3    Kingsley, G.H.4    Fisher, S.A.5
  • 40
    • 25444455578 scopus 로고    scopus 로고
    • Association of the PTPN22 C1858T single-nucleotide polymorphism with rheumatoid arthritis phenotypes in an inception cohort
    • Wesoly J, van der Helm-van Mil AH, Toes RE, Chokkalingam AP, Carlton VE, Begovich AB et al. Association of the PTPN22 C1858T single-nucleotide polymorphism with rheumatoid arthritis phenotypes in an inception cohort. Arthritis Rheum 2005; 52: 2948-2950.
    • (2005) Arthritis Rheum , vol.52 , pp. 2948-2950
    • Wesoly, J.1    Van Der Helm-Van Mil, A.H.2    Toes, R.E.3    Chokkalingam, A.P.4    Carlton, V.E.5    Begovich, A.B.6
  • 41
    • 34047092890 scopus 로고    scopus 로고
    • The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch population
    • Wesoly J, Hu X, Thabet MM, Chang M, Uh H, Allaart CF et al. The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch population. Rheumatology (Oxford) 2007; 46: 617-621.
    • (2007) Rheumatology (Oxford) , vol.46 , pp. 617-621
    • Wesoly, J.1    Hu, X.2    Thabet, M.M.3    Chang, M.4    Uh, H.5    Allaart, C.F.6
  • 42
    • 25444507438 scopus 로고    scopus 로고
    • Differential association of the PTPN22 coding variant with autoimmune diseases in a Dutch population
    • Zhernakova A, Eerligh P, Wijmenga C, Barrera P, Roep BO, Koeleman BP. Differential association of the PTPN22 coding variant with autoimmune diseases in a Dutch population. Genes Immun 2005; 6: 459-461.
    • (2005) Genes Immun , vol.6 , pp. 459-461
    • Zhernakova, A.1    Eerligh, P.2    Wijmenga, C.3    Barrera, P.4    Roep, B.O.5    Koeleman, B.P.6
  • 43
    • 59149101024 scopus 로고    scopus 로고
    • Role of HLA-DRB1 and PTPN22 genes in susceptibility to juvenile idiopathic arthritis in Hungarian patients
    • Pazar B, Gergely Jr P, Nagy ZB, Gombos T, Pozsonyi E, Rajczy K et al. Role of HLA-DRB1 and PTPN22 genes in susceptibility to juvenile idiopathic arthritis in Hungarian patients. Clin Exp Rheumatol 2008; 26: 1146-1152.
    • (2008) Clin Exp Rheumatol , vol.26 , pp. 1146-1152
    • Pazar, B.1    Gergely Jr., P.2    Nagy, Z.B.3    Gombos, T.4    Pozsonyi, E.5    Rajczy, K.6
  • 44
    • 27844441996 scopus 로고    scopus 로고
    • No evidence for association between 1858 C/T single-nucleotide polymorphism of PTPN22 gene and primary Sjogren's syndrome
    • Ittah M, Gottenberg JE, Proust A, Hachulla E, Puechal X, Loiseau P et al. No evidence for association between 1858 C/T single-nucleotide polymorphism of PTPN22 gene and primary Sjogren's syndrome. Genes Immun 2005; 6: 457-458.
    • (2005) Genes Immun , vol.6 , pp. 457-458
    • Ittah, M.1    Gottenberg, J.E.2    Proust, A.3    Hachulla, E.4    Puechal, X.5    Loiseau, P.6
  • 47
    • 23844554578 scopus 로고    scopus 로고
    • C1858T functional variant of PTPN22 gene is not associated with celiac disease genetic predisposition
    • Rueda B, Nunez C, Orozco G, Lopez-Nevot MA, de la Concha EG, Martin J et al. C1858T functional variant of PTPN22 gene is not associated with celiac disease genetic predisposition. Hum Immunol 2005; 66: 848-852.
    • (2005) Hum Immunol , vol.66 , pp. 848-852
    • Rueda, B.1    Nunez, C.2    Orozco, G.3    Lopez-Nevot, M.A.4    De La Concha, E.G.5    Martin, J.6
  • 49
    • 42249094392 scopus 로고    scopus 로고
    • The PTPN22-1858C4T (R620W) functional polymorphism is associated with generalized vitiligo in the Romanian population
    • Laberge GS, Birlea SA, Fain PR, Spritz RA. The PTPN22-1858C4T (R620W) functional polymorphism is associated with generalized vitiligo in the Romanian population. Pigment Cell Melanoma Res 2008; 21: 206-208.
    • (2008) Pigment Cell Melanoma Res , vol.21 , pp. 206-208
    • Laberge, G.S.1    Birlea, S.A.2    Fain, P.R.3    Spritz, R.A.4
  • 50
    • 35348951109 scopus 로고    scopus 로고
    • Evaluating the role of the genetic variations of PTPN22 NFKB1, and FcGRIIIA genes in inflammatory bowel disease: A meta-analysis
    • Latiano A, Palmieri O, Valvano MR, Bossa F, Latiano T, Corritore G et al. Evaluating the role of the genetic variations of PTPN22, NFKB1, and FcGRIIIA genes in inflammatory bowel disease: a meta-analysis. Inflamm Bowel Dis 2007; 13: 1212-1219.
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 1212-1219
    • Latiano, A.1    Palmieri, O.2    Valvano, M.R.3    Bossa, F.4    Latiano, T.5    Corritore, G.6
  • 51
    • 44449167234 scopus 로고    scopus 로고
    • The protein tyrosine phosphatase nonreceptor 22 (PTPN22) is associated with high GAD antibody titer in latent autoimmune diabetes in adults: Non Insulin Requiring Autoimmune Diabetes (NIRAD) Study 3
    • Petrone A, Suraci C, Capizzi M, Giaccari A, Bosi E, Tiberti C et al. The protein tyrosine phosphatase nonreceptor 22 (PTPN22) is associated with high GAD antibody titer in latent autoimmune diabetes in adults: Non Insulin Requiring Autoimmune Diabetes (NIRAD) Study 3. Diabetes Care 2008; 31: 534-538.
    • (2008) Diabetes Care , vol.31 , pp. 534-538
    • Petrone, A.1    Suraci, C.2    Capizzi, M.3    Giaccari, A.4    Bosi, E.5    Tiberti, C.6
  • 52
    • 38849128211 scopus 로고    scopus 로고
    • Association between PTPN22 C1858T and type 1 diabetes: A replication in continental Italy
    • Saccucci P, Del DE, Rapini N, Verrotti A, Piccinini S, Maccari A et al. Association between PTPN22 C1858T and type 1 diabetes: a replication in continental Italy. Tissue Antigens 2008; 71: 234-237.
    • (2008) Tissue Antigens , vol.71 , pp. 234-237
    • Saccucci, P.1    Del De Rapini, N.2    Verrotti, A.3    Piccinini, S.4    MacCari, A.5
  • 54
    • 79955670518 scopus 로고    scopus 로고
    • Association of the PTPN22 R620W polymorphism with increased risk for SLE in the genetically homogeneous population of Crete
    • Eliopoulos E, Zervou MI, Andreou A, Dimopoulou K, Cosmidis N, Voloudakis G et al. Association of the PTPN22 R620W polymorphism with increased risk for SLE in the genetically homogeneous population of Crete. Lupus 2011; 20: 501-506.
    • (2011) Lupus , vol.20 , pp. 501-506
    • Eliopoulos, E.1    Zervou, M.I.2    Andreou, A.3    Dimopoulou, K.4    Cosmidis, N.5    Voloudakis, G.6
  • 56
    • 42049096857 scopus 로고    scopus 로고
    • Association of functional variants of PTPN22 and tp53 in psoriatic arthritis: A case-control study
    • Butt C, Peddle L, Greenwood C, Hamilton S, Gladman D, Rahman P. Association of functional variants of PTPN22 and tp53 in psoriatic arthritis: a case-control study. Arthritis Res Ther 2006; 8: R27.
    • (2006) Arthritis Res Ther , vol.8
    • Butt, C.1    Peddle, L.2    Greenwood, C.3    Hamilton, S.4    Gladman, D.5    Rahman, P.6
  • 57
    • 77954318062 scopus 로고    scopus 로고
    • Association between the 1858T allele of the protein tyrosine phosphatase nonreceptor type 22 and type 1 diabetes in a Brazilian population
    • Chagastelles PC, Romitti M, Trein MR, Bandinelli E, Tschiedel B, Nardi NB. Association between the 1858T allele of the protein tyrosine phosphatase nonreceptor type 22 and type 1 diabetes in a Brazilian population. Tissue Antigens 2010; 76: 144-148.
    • (2010) Tissue Antigens , vol.76 , pp. 144-148
    • Chagastelles, P.C.1    Romitti, M.2    Trein, M.R.3    Bandinelli, E.4    Tschiedel, B.5    Nardi, N.B.6
  • 58
    • 33645136222 scopus 로고    scopus 로고
    • Evaluating the role of the 620W allele of protein tyrosine phosphatase PTPN22 in Crohn's disease and multiple sclerosis
    • De Jager PL, Sawcer S, Waliszewska A, Farwell L, Wild G, Cohen A et al. Evaluating the role of the 620W allele of protein tyrosine phosphatase PTPN22 in Crohn's disease and multiple sclerosis. Eur J Hum Genet 2006; 14: 317-321.
    • (2006) Eur J Hum Genet , vol.14 , pp. 317-321
    • De Jager, P.L.1    Sawcer, S.2    Waliszewska, A.3    Farwell, L.4    Wild, G.5    Cohen, A.6
  • 61
    • 33845663156 scopus 로고    scopus 로고
    • Association of the PTPN22 R620W polymorphism with anti-topoisomerase I-and anticentromere antibody-positive systemic sclerosis
    • Gourh P, Tan FK, Assassi S, Ahn CW, McNearney TA, Fischbach M et al. Association of the PTPN22 R620W polymorphism with anti-topoisomerase I-and anticentromere antibody-positive systemic sclerosis. Arthritis Rheum 2006; 54: 3945-3953.
    • (2006) Arthritis Rheum , vol.54 , pp. 3945-3953
    • Gourh, P.1    Tan, F.K.2    Assassi, S.3    Ahn, C.W.4    McNearney, T.A.5    Fischbach, M.6
  • 62
    • 75349113494 scopus 로고    scopus 로고
    • Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations
    • Gourh P, Agarwal SK, Martin E, Divecha D, Rueda B, Bunting H et al. Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations. J Autoimmun 2010; 34: 155-162.
    • (2010) J Autoimmun , vol.34 , pp. 155-162
    • Gourh, P.1    Agarwal, S.K.2    Martin, E.3    Divecha, D.4    Rueda, B.5    Bunting, H.6
  • 63
    • 79955480289 scopus 로고    scopus 로고
    • Association between type 1 diabetes and GWAS SNPs in the southeast US Caucasian population
    • Reddy MV, Wang H, Liu S, Bode B, Reed JC, Steed RD et al. Association between type 1 diabetes and GWAS SNPs in the southeast US Caucasian population. Genes Immun 2011; 12: 208-212.
    • (2011) Genes Immun , vol.12 , pp. 208-212
    • Reddy, M.V.1    Wang, H.2    Liu, S.3    Bode, B.4    Reed, J.C.5    Steed, R.D.6
  • 66
  • 67
    • 22244442459 scopus 로고    scopus 로고
    • Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not Crohn's disease, in Canadian populations
    • van OM, Wintle RF, Liu X, Yazdanpanah M, Gu X, Newman B et al. Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not Crohn's disease, in Canadian populations. Arthritis Rheum 2005; 52: 1993-1998.
    • (2005) Arthritis Rheum , vol.52 , pp. 1993-1998
    • Van Om Wintle, R.F.1    Liu, X.2    Yazdanpanah, M.3    Gu, X.4    Newman, B.5
  • 69
    • 77954109368 scopus 로고    scopus 로고
    • Clinical characteristics and PTPN22 1858C/T variant analysis in Jordanian Arab vitiligo patients
    • Alkhateeb A, Qarqaz F, Al-Sabah J, Al RT. Clinical characteristics and PTPN22 1858C/T variant analysis in Jordanian Arab vitiligo patients. Mol Diagn Ther 2010; 14: 179-184.
    • (2010) Mol Diagn Ther , vol.14 , pp. 179-184
    • Alkhateeb, A.1    Qarqaz, F.2    Al-Sabah, J.3    Al, R.T.4
  • 70
    • 80052097666 scopus 로고    scopus 로고
    • The role of PTPN22 gene polymorphism in childhood immune thrombocytopenic purpura
    • Anis SK, bdel Ghany EA, Mostafa NO, Ali AA. The role of PTPN22 gene polymorphism in childhood immune thrombocytopenic purpura. Blood Coagul Fibrinolysis 2011; 22: 521-525.
    • (2011) Blood Coagul Fibrinolysis , vol.22 , pp. 521-525
    • Anis, S.K.1    Bdel Ghany, E.A.2    Mostafa, N.O.3    Ali, A.A.4
  • 71
    • 79958767721 scopus 로고    scopus 로고
    • Association of the PTPN22 gene polymorphism with autoantibody positivity in Turkish rheumatoid arthritis patients
    • Ates A, Karaaslan Y, Karatayli E, Ertugrul E, Aksaray S, Turkyilmaz A et al. Association of the PTPN22 gene polymorphism with autoantibody positivity in Turkish rheumatoid arthritis patients. Tissue Antigens 2011; 78: 56-59.
    • (2011) Tissue Antigens , vol.78 , pp. 56-59
    • Ates, A.1    Karaaslan, Y.2    Karatayli, E.3    Ertugrul, E.4    Aksaray, S.5    Turkyilmaz, A.6
  • 72
    • 67649211589 scopus 로고    scopus 로고
    • The R620W polymorphism of the protein tyrosine phosphatase 22 gene in autoimmune thyroid diseases and rheumatoid arthritis in the Tunisian population
    • Chabchoub G, Teixiera EP, Maalej A, Ben HM, Bahloul Z, Cornelis F et al. The R620W polymorphism of the protein tyrosine phosphatase 22 gene in autoimmune thyroid diseases and rheumatoid arthritis in the Tunisian population. Ann Hum Biol 2009; 36: 342-349.
    • (2009) Ann Hum Biol , vol.36 , pp. 342-349
    • Chabchoub, G.1    Teixiera, E.P.2    Maalej, A.3    Ben, H.M.4    Bahloul, Z.5    Cornelis, F.6
  • 73
    • 68249090600 scopus 로고    scopus 로고
    • Association of PTPN22 gene functional variants with development of pulmonary tuberculosis in Moroccan population
    • Lamsyah H, Rueda B, Baassi L, Elaouad R, Bottini N, Sadki K et al. Association of PTPN22 gene functional variants with development of pulmonary tuberculosis in Moroccan population. Tissue Antigens 2009; 74: 228-232.
    • (2009) Tissue Antigens , vol.74 , pp. 228-232
    • Lamsyah, H.1    Rueda, B.2    Baassi, L.3    Elaouad, R.4    Bottini, N.5    Sadki, K.6
  • 75
    • 76149110070 scopus 로고    scopus 로고
    • Lymphoid tyrosine phosphatase R620W variant and inflammatory bowel disease in Tunisia
    • Sfar I, Ben AW, Mouelhi L, Aouadi H, Ben RT, Makhlouf M et al. Lymphoid tyrosine phosphatase R620W variant and inflammatory bowel disease in Tunisia. World J Gastroenterol 2010; 16: 479-483.
    • (2010) World J Gastroenterol , vol.16 , pp. 479-483
    • Sfar, I.1    Ben, A.W.2    Mouelhi, L.3    Aouadi, H.4    Ben, R.T.5    Makhlouf, M.6
  • 76
    • 79952464224 scopus 로고    scopus 로고
    • The PTPN22 R620W polymorphism is not associated with systemic rheumatic diseases in South Africans
    • Tikly M, Govind N, Frost J, Ramsay M. The PTPN22 R620W polymorphism is not associated with systemic rheumatic diseases in South Africans. Rheumatology (Oxford) 2010; 49: 820-821.
    • (2010) Rheumatology (Oxford) , vol.49 , pp. 820-821
    • Tikly, M.1    Govind, N.2    Frost, J.3    Ramsay, M.4
  • 77
    • 33750218666 scopus 로고    scopus 로고
    • Haplotype analysis revealed no association between the PTPN22 gene and RA in a Japanese population
    • Ikari K, Momohara S, Inoue E, Tomatsu T, Hara M, Yamanaka H et al. Haplotype analysis revealed no association between the PTPN22 gene and RA in a Japanese population. Rheumatology (Oxford) 2006; 45: 1345-1348.
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 1345-1348
    • Ikari, K.1    Momohara, S.2    Inoue, E.3    Tomatsu, T.4    Hara, M.5    Yamanaka, H.6
  • 78
    • 33644851944 scopus 로고    scopus 로고
    • Systematic search for single nucleotide polymorphisms in a lymphoid tyrosine phosphatase gene (PTPN22): Association between a promoter polymorphism and type 1 diabetes in Asian populations
    • Kawasaki E, Awata T, Ikegami H, Kobayashi T, Maruyama T, Nakanishi K et al. Systematic search for single nucleotide polymorphisms in a lymphoid tyrosine phosphatase gene (PTPN22): association between a promoter polymorphism and type 1 diabetes in Asian populations. Am J Med Genet A 2006; 140: 586-593.
    • (2006) Am J Med Genet A , vol.140 , pp. 586-593
    • Kawasaki, E.1    Awata, T.2    Ikegami, H.3    Kobayashi, T.4    Maruyama, T.5    Nakanishi, K.6
  • 82
    • 67650709487 scopus 로고    scopus 로고
    • Recent advances in the genetics of autoimmune disease
    • Gregersen PK, Olsson LM. Recent advances in the genetics of autoimmune disease. Annu Rev Immunol 2009; 27: 363-391.
    • (2009) Annu Rev Immunol , vol.27 , pp. 363-391
    • Gregersen, P.K.1    Olsson, L.M.2
  • 83
  • 84
  • 85
    • 59649123838 scopus 로고    scopus 로고
    • The protein tyrosine phosphatase non-receptor type 22 C1858T polymorphism is a joint susceptibility locus for immunthyroiditis and autoimmune diabetes
    • Dultz G, Matheis N, Dittmar M, Rohrig B, Bender K, Kahaly GJ. The protein tyrosine phosphatase non-receptor type 22 C1858T polymorphism is a joint susceptibility locus for immunthyroiditis and autoimmune diabetes. Thyroid 2009; 19: 143-148.
    • (2009) Thyroid , vol.19 , pp. 143-148
    • Dultz, G.1    Matheis, N.2    Dittmar, M.3    Rohrig, B.4    Bender, K.5    Kahaly, G.J.6
  • 86
    • 78651112432 scopus 로고    scopus 로고
    • PTPN22 PDCD1 and CYP27B1 polymorphisms and susceptibility to type 1 diabetes in Polish patients
    • Fichna M, Zurawek M, Januszkiewicz-Lewandowska D, Fichna P, Nowak J. PTPN22, PDCD1 and CYP27B1 polymorphisms and susceptibility to type 1 diabetes in Polish patients. Int J Immunogenet 2010; 37: 367-372.
    • (2010) Int J Immunogenet , vol.37 , pp. 367-372
    • Fichna, M.1    Zurawek, M.2    Januszkiewicz-Lewandowska, D.3    Fichna, P.4    Nowak, J.5
  • 87
    • 29644432112 scopus 로고    scopus 로고
    • Sexspecific association of PTPN22 1858T with type 1 diabetes but not with Hashimoto's thyroiditis or Addison's disease in the German population
    • Kahles H, Ramos-Lopez E, Lange B, Zwermann O, Reincke M, Badenhoop K. Sexspecific association of PTPN22 1858T with type 1 diabetes but not with Hashimoto's thyroiditis or Addison's disease in the German population. Eur J Endocrinol 2005; 153: 895-899.
    • (2005) Eur J Endocrinol , vol.153 , pp. 895-899
    • Kahles, H.1    Ramos-Lopez, E.2    Lange, B.3    Zwermann, O.4    Reincke, M.5    Badenhoop, K.6
  • 88
    • 77951052048 scopus 로고    scopus 로고
    • Genetic risk markers related to diabetes-associated autoantibodies in young patients with type 1 diabetes in Berlin Germany
    • Kordonouri O, Hartmann R, Charpentier N, Knip M, Danne T, Ilonen J. Genetic risk markers related to diabetes-associated autoantibodies in young patients with type 1 diabetes in Berlin, Germany. Exp Clin Endocrinol Diabetes 2010; 118: 245-249.
    • (2010) Exp Clin Endocrinol Diabetes , vol.118 , pp. 245-249
    • Kordonouri, O.1    Hartmann, R.2    Charpentier, N.3    Knip, M.4    Danne, T.5    Ilonen, J.6
  • 90
    • 77954887535 scopus 로고    scopus 로고
    • The association between the PTPN22 1858C4T variant and type 1 diabetes depends on HLA risk and GAD65 autoantibodies
    • Maziarz M, Janer M, Roach JC, Hagopian W, Palmer JP, Deutsch K et al. The association between the PTPN22 1858C4T variant and type 1 diabetes depends on HLA risk and GAD65 autoantibodies. Genes Immun 2010; 11: 406-415.
    • (2010) Genes Immun , vol.11 , pp. 406-415
    • Maziarz, M.1    Janer, M.2    Roach, J.C.3    Hagopian, W.4    Palmer, J.P.5    Deutsch, K.6
  • 93
    • 45149121724 scopus 로고    scopus 로고
    • Testing for linkage and association with rheumatoid arthritis a ptpn22 promoter polymorphism reported to be associated and linked with type 1 diabetes in the Caucasian population
    • Dieude P, Teixeira VH, Pierlot C, Cornelis F, Petit-Teixeira E. Testing for linkage and association with rheumatoid arthritis a ptpn22 promoter polymorphism reported to be associated and linked with type 1 diabetes in the Caucasian population. Ann Rheum Dis 2008; 67: 900-901.
    • (2008) Ann Rheum Dis , vol.67 , pp. 900-901
    • Dieude, P.1    Teixeira, V.H.2    Pierlot, C.3    Cornelis, F.4    Petit-Teixeira, E.5
  • 94
    • 67349138539 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase gene C1858T allele confers risk for rheumatoid arthritis in Hungarian subjects
    • Farago B, Talian GC, Komlosi K, Nagy G, Berki T, Gyetvai A et al. Protein tyrosine phosphatase gene C1858T allele confers risk for rheumatoid arthritis in Hungarian subjects. Rheumatol Int 2009; 29: 793-796.
    • (2009) Rheumatol Int , vol.29 , pp. 793-796
    • Farago, B.1    Talian, G.C.2    Komlosi, K.3    Nagy, G.4    Berki, T.5    Gyetvai, A.6
  • 95
    • 33747836301 scopus 로고    scopus 로고
    • Effects of PTPN22 C1858T polymorphism on susceptibility and clinical characteristics of British Caucasian rheumatoid arthritis patients
    • Harrison P, Pointon JJ, Farrar C, Brown MA, Wordsworth BP. Effects of PTPN22 C1858T polymorphism on susceptibility and clinical characteristics of British Caucasian rheumatoid arthritis patients. Rheumatology (Oxford) 2006; 45: 1009-1011.
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 1009-1011
    • Harrison, P.1    Pointon, J.J.2    Farrar, C.3    Brown, M.A.4    Wordsworth, B.P.5
  • 96
    • 20744460317 scopus 로고    scopus 로고
    • Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population: Further support that PTPN22 is an autoimmunity gene
    • Hinks A, Barton A, John S, Bruce I, Hawkins C, Griffiths CE et al. Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population: further support that PTPN22 is an autoimmunity gene. Arthritis Rheum 2005; 52: 1694-1699.
    • (2005) Arthritis Rheum , vol.52 , pp. 1694-1699
    • Hinks, A.1    Barton, A.2    John, S.3    Bruce, I.4    Hawkins, C.5    Griffiths, C.E.6
  • 97
    • 20144388808 scopus 로고    scopus 로고
    • The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dosedependent manner but not with HLA-SE status
    • Lee AT, Li W, Liew A, Bombardier C, Weisman M, Massarotti EM et al. The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dosedependent manner but not with HLA-SE status. Genes Immun 2005; 6: 129-133.
    • (2005) Genes Immun , vol.6 , pp. 129-133
    • Lee, A.T.1    Li, W.2    Liew, A.3    Bombardier, C.4    Weisman, M.5    Massarotti, E.M.6
  • 98
    • 78650013787 scopus 로고    scopus 로고
    • PTPN22 1858C4T polymorphism is strongly associated with rheumatoid arthritis but not with a response to methotrexate therapy
    • Majorczyk E, Pawlik A, Kusnierczyk P. PTPN22 1858C4T polymorphism is strongly associated with rheumatoid arthritis but not with a response to methotrexate therapy. Int Immunopharmacol 2010; 10: 1626-1629.
    • (2010) Int Immunopharmacol , vol.10 , pp. 1626-1629
    • Majorczyk, E.1    Pawlik, A.2    Kusnierczyk, P.3
  • 99
    • 77950456388 scopus 로고    scopus 로고
    • Evaluation of the rheumatoid arthritis susceptibility loci HLA-DRB1, PTPN22, OLIG3/TNFAIP3, STAT4 and TRAF1/C5 in an inception cohort
    • Morgan AW, Robinson JI, Conaghan PG, Martin SG, Hensor EM, Morgan MD et al. Evaluation of the rheumatoid arthritis susceptibility loci HLA-DRB1, PTPN22, OLIG3/TNFAIP3, STAT4 and TRAF1/C5 in an inception cohort. Arthritis Res Ther 2010; 12: R57.
    • (2010) Arthritis Res Ther , vol.12
    • Morgan, A.W.1    Robinson, J.I.2    Conaghan, P.G.3    Martin, S.G.4    Hensor, E.M.5    Morgan, M.D.6
  • 100
    • 33845617605 scopus 로고    scopus 로고
    • Rheumatoid arthritis association with the FCRL3-169C polymorphism is restricted to PTPN22 1858T-homozygous individuals in a Canadian population
    • Newman WG, Zhang Q, Liu X, Walker E, Ternan H, Owen J et al. Rheumatoid arthritis association with the FCRL3-169C polymorphism is restricted to PTPN22 1858T-homozygous individuals in a Canadian population. Arthritis Rheum 2006; 54: 3820-3827.
    • (2006) Arthritis Rheum , vol.54 , pp. 3820-3827
    • Newman, W.G.1    Zhang, Q.2    Liu, X.3    Walker, E.4    Ternan, H.5    Owen, J.6
  • 101
    • 28144441356 scopus 로고    scopus 로고
    • Replication of putative candidate-gene associations with rheumatoid arthritis in 44,000 samples from North America and Sweden: Association of susceptibility with PTPN22, CTLA4, and PADI4
    • Plenge RM, Padyukov L, Remmers EF, Purcell S, Lee AT, Karlson EW et al. Replication of putative candidate-gene associations with rheumatoid arthritis in 44,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4. Am J Hum Genet 2005; 77: 1044-1060.
    • (2005) Am J Hum Genet , vol.77 , pp. 1044-1060
    • Plenge, R.M.1    Padyukov, L.2    Remmers, E.F.3    Purcell, S.4    Lee, A.T.5    Karlson, E.W.6
  • 103
    • 20844452226 scopus 로고    scopus 로고
    • Association analysis of the 1858C4T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases
    • Viken MK, Amundsen SS, Kvien TK, Boberg KM, Gilboe IM, Lilleby V et al. Association analysis of the 1858C4T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases. Genes Immun 2005; 6: 271-273.
    • (2005) Genes Immun , vol.6 , pp. 271-273
    • Viken, M.K.1    Amundsen, S.S.2    Kvien, T.K.3    Boberg, K.M.4    Gilboe, I.M.5    Lilleby, V.6
  • 104
    • 84855225058 scopus 로고    scopus 로고
    • No association of PTPN22 R620 W gene polymorphism with rheumatic heart disease and systemic lupus erythematosus
    • Aksoy R, Duman T, Keskin O, Duzgun N. No association of PTPN22 R620 W gene polymorphism with rheumatic heart disease and systemic lupus erythematosus. Mol Biol Rep 2011; 38: 5393-5396.
    • (2011) Mol Biol Rep , vol.38 , pp. 5393-5396
    • Aksoy, R.1    Duman, T.2    Keskin, O.3    Duzgun, N.4
  • 105
    • 33746957905 scopus 로고    scopus 로고
    • Evaluation of the genetic association of the PTPN22 R620W polymorphism in familial and sporadic systemic lupus erythematosus
    • Kaufman KM, Kelly JA, Herring BJ, Adler AJ, Glenn SB, Namjou B et al. Evaluation of the genetic association of the PTPN22 R620W polymorphism in familial and sporadic systemic lupus erythematosus. Arthritis Rheum 2006; 54: 2533-2540.
    • (2006) Arthritis Rheum , vol.54 , pp. 2533-2540
    • Kaufman, K.M.1    Kelly, J.A.2    Herring, B.J.3    Adler, A.J.4    Glenn, S.B.5    Namjou, B.6
  • 106
    • 19944433325 scopus 로고    scopus 로고
    • Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus
    • Orozco G, Sanchez E, Gonzalez-Gay MA, Lopez-Nevot MA, Torres B, Caliz R et al. Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus. Arthritis Rheum 2005; 52: 219-224.
    • (2005) Arthritis Rheum , vol.52 , pp. 219-224
    • Orozco, G.1    Sanchez, E.2    Gonzalez-Gay, M.A.3    Lopez-Nevot, M.A.4    Torres, B.5    Caliz, R.6
  • 107
    • 59249107796 scopus 로고    scopus 로고
    • Contribution of the R620W polymorphism of protein tyrosine phosphatase non-receptor 22 to systemic lupus erythematosus in Poland
    • Piotrowski P, Lianeri M, Wudarski M, Lacki JK, Jagodzinski PP. Contribution of the R620W polymorphism of protein tyrosine phosphatase non-receptor 22 to systemic lupus erythematosus in Poland. Clin Exp Rheumatol 2008; 26: 1099-1102.
    • (2008) Clin Exp Rheumatol , vol.26 , pp. 1099-1102
    • Piotrowski, P.1    Lianeri, M.2    Wudarski, M.3    Lacki, J.K.4    Jagodzinski, P.P.5
  • 108
    • 28544444365 scopus 로고    scopus 로고
    • The R620W C/T polymorphism of the gene PTPN22 is associated with SLE independently of the association of PDCD1
    • Reddy MV, Johansson M, Sturfelt G, Jonsen A, Gunnarsson I, Svenungsson E et al. The R620W C/T polymorphism of the gene PTPN22 is associated with SLE independently of the association of PDCD1. Genes Immun 2005; 6: 658-662.
    • (2005) Genes Immun , vol.6 , pp. 658-662
    • Reddy, M.V.1    Johansson, M.2    Sturfelt, G.3    Jonsen, A.4    Gunnarsson, I.5    Svenungsson, E.6
  • 109
    • 8744266374 scopus 로고    scopus 로고
    • The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease
    • Velaga MR, Wilson V, Jennings CE, Owen CJ, Herington S, Donaldson PT et al. The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease. J Clin Endocrinol Metab 2004; 89: 5862-5865.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 5862-5865
    • Velaga, M.R.1    Wilson, V.2    Jennings, C.E.3    Owen, C.J.4    Herington, S.5    Donaldson, P.T.6
  • 110
    • 60349083325 scopus 로고    scopus 로고
    • The tryptophan 620 allele of the lymphoid tyrosine phosphatase (PTPN22) gene predisposes to autoimmune Addison's disease
    • Roycroft M, Fichna M, McDonald D, Owen K, Zurawek M, Gryczynska M et al. The tryptophan 620 allele of the lymphoid tyrosine phosphatase (PTPN22) gene predisposes to autoimmune Addison's disease. Clin Endocrinol (Oxford) 2009; 70: 358-362.
    • (2009) Clin Endocrinol (Oxford) , vol.70 , pp. 358-362
    • Roycroft, M.1    Fichna, M.2    McDonald, D.3    Owen, K.4    Zurawek, M.5    Gryczynska, M.6
  • 111
    • 73149083260 scopus 로고    scopus 로고
    • Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis
    • Carr EJ, Niederer HA, Williams J, Harper L, Watts RA, Lyons PA et al. Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis. BMC Med Genet 2009; 10: 121.
    • (2009) BMC Med Genet , vol.10 , pp. 121
    • Carr, E.J.1    Niederer, H.A.2    Williams, J.3    Harper, L.4    Watts, R.A.5    Lyons, P.A.6
  • 113
    • 77953722134 scopus 로고    scopus 로고
    • Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis
    • Hinks A, Eyre S, Ke X, Barton A, Martin P, Flynn E et al. Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis. Ann Rheum Dis 2010; 69: 1049-1053.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1049-1053
    • Hinks, A.1    Eyre, S.2    Ke, X.3    Barton, A.4    Martin, P.5    Flynn, E.6
  • 114
  • 115
    • 73849107060 scopus 로고    scopus 로고
    • The PTPN22 gain-of-function\+1858T(\+) genotypes correlate with low IL-2 expression in thymomas and predispose to myasthenia gravis
    • Chuang WY, Strobel P, Belharazem D, Rieckmann P, Toyka KV, Nix W et al. The PTPN22 gain-of-function\+1858T(\+) genotypes correlate with low IL-2 expression in thymomas and predispose to myasthenia gravis. Genes Immun 2009; 10: 667-672.
    • (2009) Genes Immun , vol.10 , pp. 667-672
    • Chuang, W.Y.1    Strobel, P.2    Belharazem, D.3    Rieckmann, P.4    Toyka, K.V.5    Nix, W.6
  • 116
    • 67449141649 scopus 로고    scopus 로고
    • The autoimmunity-related polymorphism PTPN22 1858C/T is associated with antititin antibody-positive myasthenia gravis
    • Greve B, Hoffmann P, Illes Z, Rozsa C, Berger K, Weissert R et al. The autoimmunity-related polymorphism PTPN22 1858C/T is associated with antititin antibody-positive myasthenia gravis. Hum Immunol 2009; 70: 540-542.
    • (2009) Hum Immunol , vol.70 , pp. 540-542
    • Greve, B.1    Hoffmann, P.2    Illes, Z.3    Rozsa, C.4    Berger, K.5    Weissert, R.6
  • 117
    • 58949097704 scopus 로고    scopus 로고
    • Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship
    • Anderson CA, Massey DC, Barrett JC, Prescott NJ, Tremelling M, Fisher SA et al. Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship. Gastroenterology 2009; 136: 523-529.
    • (2009) Gastroenterology , vol.136 , pp. 523-529
    • Anderson, C.A.1    Massey, D.C.2    Barrett, J.C.3    Prescott, N.J.4    Tremelling, M.5    Fisher, S.A.6
  • 119
    • 77951765348 scopus 로고    scopus 로고
    • Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus
    • Radstake TR, Gorlova O, Rueda B, Martin JE, Alizadeh BZ, Palomino-Morales R et al. Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. Nat Genet 2010; 42: 426-429.
    • (2010) Nat Genet , vol.42 , pp. 426-429
    • Radstake, T.R.1    Gorlova, O.2    Rueda, B.3    Martin, J.E.4    Alizadeh, B.Z.5    Palomino-Morales, R.6
  • 120
  • 121
    • 23844551123 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase gene (PTPN22) polymorphism in multiple sclerosis
    • Matesanz F, Rueda B, Orozco G, Fernandez O, Leyva L, Alcina A et al. Protein tyrosine phosphatase gene (PTPN22) polymorphism in multiple sclerosis. J Neurol 2005; 252: 994-995.
    • (2005) J Neurol , vol.252 , pp. 994-995
    • Matesanz, F.1    Rueda, B.2    Orozco, G.3    Fernandez, O.4    Leyva, L.5    Alcina, A.6
  • 122
    • 33646252483 scopus 로고    scopus 로고
    • Male restricted genetic association of variant R620W in PTPN22 with psoriatic arthritis
    • Huffmeier U, Reis A, Steffens M, Lascorz J, Bohm B, Lohmann J et al. Male restricted genetic association of variant R620W in PTPN22 with psoriatic arthritis. J Invest Dermatol 2006; 126: 932-935.
    • (2006) J Invest Dermatol , vol.126 , pp. 932-935
    • Huffmeier, U.1    Reis, A.2    Steffens, M.3    Lascorz, J.4    Bohm, B.5    Lohmann, J.6
  • 123
    • 42049120079 scopus 로고    scopus 로고
    • Polymorphisms in the PTPN22 region are associated with psoriasis of early onset
    • Smith RL, Warren RB, Eyre S, Ke X, Young HS, Allen M et al. Polymorphisms in the PTPN22 region are associated with psoriasis of early onset. Br J Dermatol 2008; 158: 962-968.
    • (2008) Br J Dermatol , vol.158 , pp. 962-968
    • Smith, R.L.1    Warren, R.B.2    Eyre, S.3    Ke, X.4    Young, H.S.5    Allen, M.6
  • 126
    • 77954223152 scopus 로고    scopus 로고
    • Genome-wide association study in alopecia areata implicates both innate and adaptive immunity
    • Petukhova L, Duvic M, Hordinsky M, Norris D, Price V, Shimomura Y et al. Genome-wide association study in alopecia areata implicates both innate and adaptive immunity. Nature 2010; 466: 113-117.
    • (2010) Nature , vol.466 , pp. 113-117
    • Petukhova, L.1    Duvic, M.2    Hordinsky, M.3    Norris, D.4    Price, V.5    Shimomura, Y.6
  • 127
    • 54949119487 scopus 로고    scopus 로고
    • The protein tyrosine phosphatase N22 gene is associated with juvenile and adult idiopathic inflammatory myopathy independent of the HLA 8.1 haplotype in British Caucasian patients
    • Chinoy H, Platt H, Lamb JA, Betteridge Z, Gunawardena H, Fertig N et al. The protein tyrosine phosphatase N22 gene is associated with juvenile and adult idiopathic inflammatory myopathy independent of the HLA 8.1 haplotype in British Caucasian patients. Arthritis Rheum 2008; 58: 3247-3254.
    • (2008) Arthritis Rheum , vol.58 , pp. 3247-3254
    • Chinoy, H.1    Platt, H.2    Lamb, J.A.3    Betteridge, Z.4    Gunawardena, H.5    Fertig, N.6
  • 128
    • 77956480474 scopus 로고    scopus 로고
    • Increased representation of the PTPN22 mutation in patients with immune thrombocytopenia
    • D'Silva KJ, Zamora MB, Gerlach J, Schwartz KA. Increased representation of the PTPN22 mutation in patients with immune thrombocytopenia. J Thromb Haemost 2010; 8: 2076-2078.
    • (2010) J Thromb Haemost , vol.8 , pp. 2076-2078
    • D'Silva, K.J.1    Zamora, M.B.2    Gerlach, J.3    Schwartz, K.A.4
  • 129
    • 59349110453 scopus 로고    scopus 로고
    • Genotype analysis of polymorphisms in autoimmune susceptibility genes, CTLA-4 and PTPN22, in an acute anterior uveitis cohort
    • Martin TM, Bye L, Modi N, Stanford MR, Vaughan R, Smith JR et al. Genotype analysis of polymorphisms in autoimmune susceptibility genes, CTLA-4 and PTPN22, in an acute anterior uveitis cohort. Mol Vis 2009; 15: 208-212.
    • (2009) Mol Vis , vol.15 , pp. 208-212
    • Martin, T.M.1    Bye, L.2    Modi, N.3    Stanford, M.R.4    Vaughan, R.5    Smith, J.R.6
  • 131
    • 33646231253 scopus 로고    scopus 로고
    • Lack of association between ankylosing spondylitis and a functional polymorphism of PTPN22 proposed as a general susceptibility marker for autoimmunity
    • Orozco G, Garcia-Porrua C, Lopez-Nevot MA, Raya E, Gonzalez-Gay MA, Martin J. Lack of association between ankylosing spondylitis and a functional polymorphism of PTPN22 proposed as a general susceptibility marker for autoimmunity. Ann Rheum Dis 2006; 65: 687-688.
    • (2006) Ann Rheum Dis , vol.65 , pp. 687-688
    • Orozco, G.1    Garcia-Porrua, C.2    Lopez-Nevot, M.A.3    Raya, E.4    Gonzalez-Gay, M.A.5    Martin, J.6
  • 132
    • 75749085686 scopus 로고    scopus 로고
    • Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci
    • Reveille JD, Sims AM, Danoy P, Evans DM, Leo P, Pointon JJ et al. Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. Nat Genet 2010; 42: 123-127.
    • (2010) Nat Genet , vol.42 , pp. 123-127
    • Reveille, J.D.1    Sims, A.M.2    Danoy, P.3    Evans, D.M.4    Leo, P.5    Pointon, J.J.6
  • 133
    • 67149095289 scopus 로고    scopus 로고
    • Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants
    • Hirschfield GM, Liu X, Xu C, Lu Y, Xie G, Lu Y et al. Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. N Engl J Med 2009; 360: 2544-2555.
    • (2009) N Engl J Med , vol.360 , pp. 2544-2555
    • Hirschfield, G.M.1    Liu, X.2    Xu, C.3    Lu, Y.4    Xie, G.5    Lu, Y.6
  • 135
    • 49049114366 scopus 로고    scopus 로고
    • Pemphigus vulgaris and its active disease mouse model
    • Amagai M. Pemphigus vulgaris and its active disease mouse model. Curr Dir Autoimmun 2008; 10: 167-181.
    • (2008) Curr Dir Autoimmun , vol.10 , pp. 167-181
    • Amagai, M.1
  • 137
    • 34548323860 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase PTPN22 in human autoimmunity
    • Vang T, Miletic AV, Bottini N, Mustelin T. Protein tyrosine phosphatase PTPN22 in human autoimmunity. Autoimmunity 2007; 40: 453-461.
    • (2007) Autoimmunity , vol.40 , pp. 453-461
    • Vang, T.1    Miletic, A.V.2    Bottini, N.3    Mustelin, T.4
  • 138
    • 80052376347 scopus 로고    scopus 로고
    • The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans
    • Menard L, Saadoun D, Isnardi I, Ng YS, Meyers G, Massad C et al. The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans. J Clin Invest 2011; 121: 3635-3644.
    • (2011) J Clin Invest , vol.121 , pp. 3635-3644
    • Menard, L.1    Saadoun, D.2    Isnardi, I.3    Ng, Y.S.4    Meyers, G.5    Massad, C.6
  • 139
    • 80052239824 scopus 로고    scopus 로고
    • The autoimmune disease-associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness
    • Zhang J, Zahir N, Jiang Q, Miliotis H, Heyraud S, Meng X et al. The autoimmune disease-associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness. Nat Genet 2011; 43: 902-907.
    • (2011) Nat Genet , vol.43 , pp. 902-907
    • Zhang, J.1    Zahir, N.2    Jiang, Q.3    Miliotis, H.4    Heyraud, S.5    Meng, X.6
  • 140
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
    • Hugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001; 411: 599-603.
    • (2001) Nature , vol.411 , pp. 599-603
    • Hugot, J.P.1    Chamaillard, M.2    Zouali, H.3    Lesage, S.4    Cezard, J.P.5    Belaiche, J.6
  • 141
    • 0035978533 scopus 로고    scopus 로고
    • A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
    • Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001; 411: 603-606.
    • (2001) Nature , vol.411 , pp. 603-606
    • Ogura, Y.1    Bonen, D.K.2    Inohara, N.3    Nicolae, D.L.4    Chen, F.F.5    Ramos, R.6
  • 142
    • 0034610973 scopus 로고    scopus 로고
    • High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: Mechanisms of selection of the self-reactive repertoire
    • Anderson AC, Nicholson LB, Legge KL, Turchin V, Zaghouani H, Kuchroo VK. High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: mechanisms of selection of the self-reactive repertoire. J Exp Med 2000; 191: 761-770.
    • (2000) J Exp Med , vol.191 , pp. 761-770
    • Anderson, A.C.1    Nicholson, L.B.2    Legge, K.L.3    Turchin, V.4    Zaghouani, H.5    Kuchroo, V.K.6
  • 143
    • 0036773624 scopus 로고    scopus 로고
    • Multiple sclerosis candidate autoantigens except myelin oligodendrocyte glycoprotein are transcribed in human thymus
    • Bruno R, Sabater L, Sospedra M, Ferrer-Francesch X, Escudero D, Martinez-Caceres E et al. Multiple sclerosis candidate autoantigens except myelin oligodendrocyte glycoprotein are transcribed in human thymus. Eur J Immunol 2002; 32: 2737-2747.
    • (2002) Eur J Immunol , vol.32 , pp. 2737-2747
    • Bruno, R.1    Sabater, L.2    Sospedra, M.3    Ferrer-Francesch, X.4    Escudero, D.5    Martinez-Caceres, E.6
  • 144
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959; 22: 719-748.
    • (1959) J Natl Cancer Inst , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2


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