메뉴 건너뛰기




Volumn 22, Issue , 2014, Pages 20-32

One hormone, two actions: Anti- And pro-inflammatory effects of glucocorticoids

Author keywords

Glucocorticoid receptor; Glucocorticoids; Immunity; Inflammation; Pro inflammatory and anti inflammatory; Stress hormones

Indexed keywords

GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HORMONE; STEROID RECEPTOR; DEXAMETHASONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR AP 1; ANTIINFLAMMATORY AGENT; CRYOPYRIN; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 1BETA; INTERLEUKIN 6; PURINERGIC P2Y RECEPTOR; RNA POLYMERASE II; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

EID: 84908575796     PISSN: 10217401     EISSN: 14230216     Source Type: Journal    
DOI: 10.1159/000362724     Document Type: Article
Times cited : (343)

References (81)
  • 1
    • 0034454682 scopus 로고    scopus 로고
    • How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions
    • Sapolsky RM, Romero LM, Munck AU: How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. Endocr Rev 2000; 21: 55-89.
    • (2000) Endocr Rev , vol.21 , pp. 55-89
    • Sapolsky, R.M.1    Romero, L.M.2    Munck, A.U.3
  • 2
    • 84887016715 scopus 로고    scopus 로고
    • The biology of the glucocorticoid receptor: New signaling mechanisms in health and disease
    • Oakley RH, Cidlowski JA: The biology of the glucocorticoid receptor: new signaling mechanisms in health and disease. J Allergy Clin Immunol 2013; 132: 1033-1044.
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 1033-1044
    • Oakley, R.H.1    Cidlowski, J.A.2
  • 3
    • 84883769810 scopus 로고    scopus 로고
    • Glucocorticoid receptor signaling in health and disease
    • Kadmiel M, Cidlowski JA: Glucocorticoid receptor signaling in health and disease. Trends Pharmacol Sci 2013; 34: 518-530.
    • (2013) Trends Pharmacol Sci , vol.34 , pp. 518-530
    • Kadmiel, M.1    Cidlowski, J.A.2
  • 4
    • 18144399332 scopus 로고    scopus 로고
    • The human glucocorticoid receptor: One gene, multiple proteins and diverse responses
    • Zhou J, Cidlowski JA: The human glucocorticoid receptor: one gene, multiple proteins and diverse responses. Steroids 2005; 70: 407-417.
    • (2005) Steroids , vol.70 , pp. 407-417
    • Zhou, J.1    Cidlowski, J.A.2
  • 5
    • 84874585409 scopus 로고    scopus 로고
    • New insights into the anti-inflammatory mechanisms of glucocorticoids: An emerging role for glucocorticoid-receptormediated transactivation
    • Vandevyver S, Dejager L, Tuckermann J, Libert C: New insights into the anti-inflammatory mechanisms of glucocorticoids: An emerging role for glucocorticoid-receptormediated transactivation. Endocrinology 2013; 154: 993-1007.
    • (2013) Endocrinology , vol.154 , pp. 993-1007
    • Van De Vyver, S.1    Dejager, L.2    Tuckermann, J.3    Libert, C.4
  • 6
    • 84857362332 scopus 로고    scopus 로고
    • Maps and legends: The quest for dissociated ligands of the glucocorticoid receptor
    • Clark AR, Belvisi MG: Maps and legends: The quest for dissociated ligands of the glucocorticoid receptor. Pharmacol Ther 2012; 134: 54-67.
    • (2012) Pharmacol Ther , vol.134 , pp. 54-67
    • Clark, A.R.1    Belvisi, M.G.2
  • 7
    • 26844433194 scopus 로고    scopus 로고
    • Antiinflammatory action of glucocorticoids - new mechanisms for old drugs
    • Rhen T, Cidlowski JA: Antiinflammatory action of glucocorticoids - new mechanisms for old drugs. N Engl J Med 2005; 353: 1711-1723.
    • (2005) N Engl J Med , vol.353 , pp. 1711-1723
    • Rhen, T.1    Cidlowski, J.A.2
  • 10
    • 0023066651 scopus 로고
    • Intracellular receptor concentration limits glucocorticoid-dependent enhancer activity
    • Vanderbilt JN, Miesfeld R, Maler BA, Yamamoto KR: Intracellular receptor concentration limits glucocorticoid-dependent enhancer activity. Mol Endocrinol 1987; 1: 68-74.
    • (1987) Mol Endocrinol , vol.1 , pp. 68-74
    • Van De Rbilt, J.N.1    Miesfeld, R.2    Maler, B.A.3    Yamamoto, K.R.4
  • 11
    • 0021367753 scopus 로고
    • Down-regulation of glucocorticoid receptors in mouse lymphoma cell variants
    • Danielsen M, Stallcup MR: Down-regulation of glucocorticoid receptors in mouse lymphoma cell variants. Mol Cell Biol 1984; 4: 449- 453.
    • (1984) Mol Cell Biol , vol.4 , pp. 449-453
    • Danielsen, M.1    Stallcup, M.R.2
  • 12
    • 0028099408 scopus 로고
    • Differential tyrosine phosphorylation of jak1, jak2, and stat1 by growth hormone and interferon-gamma in im-9 cells
    • Silva CM, Lu H, Weber MJ, Thorner MO: Differential tyrosine phosphorylation of JAK1, JAK2, and STAT1 by growth hormone and interferon-gamma in IM-9 cells. J Biol Chem 1994; 269: 27532-27539.
    • (1994) J Biol Chem , vol.269 , pp. 27532-27539
    • Silva, C.M.1    Lu, H.2    Weber, M.J.3    Thorner, M.O.4
  • 13
    • 65849427529 scopus 로고    scopus 로고
    • Glucocorticoid resistance in inflammatory diseases
    • Barnes PJ, Adcock IM: Glucocorticoid resistance in inflammatory diseases. Lancet 2009; 373: 1905-1917.
    • (2009) Lancet , vol.373 , pp. 1905-1917
    • Barnes, P.J.1    Adcock, I.M.2
  • 14
    • 84875237427 scopus 로고    scopus 로고
    • The five rs of glucocorticoid action during inflammation: Ready, reinforce, repress, resolve, and restore
    • Busillo JM, Cidlowski JA: The five Rs of glucocorticoid action during inflammation: ready, reinforce, repress, resolve, and restore. Trends Endocrinol Metab 2013; 24: 109-119.
    • (2013) Trends Endocrinol Metab , vol.24 , pp. 109-119
    • Busillo, J.M.1    Cidlowski, J.A.2
  • 15
    • 0033253070 scopus 로고    scopus 로고
    • Steroid hormone receptors: Evolution, ligands, and molecular basis of biologic function
    • Whitfield GK, Jurutka PW, Haussler CA, Haussler MR: Steroid hormone receptors: evolution, ligands, and molecular basis of biologic function. J Cell Biochem 1999;suppl 32- 33: 110-122.
    • (1999) J Cell Biochem , pp. 110-122
    • Whitfield, G.K.1    Jurutka, P.W.2    Haussler, C.A.3    Haussler, M.R.4
  • 18
    • 79960912981 scopus 로고    scopus 로고
    • Glucocorticoid receptor mutants: Man-made tools for functional research
    • Beck IM, De Bosscher K, Haegeman G: Glucocorticoid receptor mutants: man-made tools for functional research. Trends Endocrinol Metab 2011; 22: 295-310.
    • (2011) Trends Endocrinol Metab , vol.22 , pp. 295-310
    • Beck, I.M.1    De Bosscher, K.2    Haegeman, G.3
  • 19
    • 0024545638 scopus 로고
    • Gene regulation by steroid hormones
    • Beato M: Gene regulation by steroid hormones. Cell 1989; 56: 335-344.
    • (1989) Cell , vol.56 , pp. 335-344
    • Beato, M.1
  • 20
    • 0026685062 scopus 로고
    • Anatomy of the steroid receptor zinc finger region
    • Freedman LP: Anatomy of the steroid receptor zinc finger region. Endocr Rev 1992; 13: 129-145.
    • (1992) Endocr Rev , vol.13 , pp. 129-145
    • Freedman, L.P.1
  • 22
    • 0034284349 scopus 로고    scopus 로고
    • Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: Negative interference of activated glucocorticoid receptor with transcription factors
    • De Bosscher K, Vanden Berghe W, Haegeman G: Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: negative interference of activated glucocorticoid receptor with transcription factors. J Neuroimmunol 2000; 109: 16-22.
    • (2000) J Neuroimmunol , vol.109 , pp. 16-22
    • De Bosscher, K.1    Van Den Berghe, W.2    Haegeman, G.3
  • 23
    • 0034636021 scopus 로고    scopus 로고
    • Glucocorticoids repress nf-κb-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell
    • De Bosscher K, Vanden Berghe W, Vermeulen L, Plaisance S, Boone E, Haegeman G: Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell. Proc Natl Acad Sci USA 2000; 97: 3919-3924.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3919-3924
    • De Bosscher, K.1    Van Den Berghe, W.2    Vermeulen, L.3    Plaisance, S.4    Boone, E.5    Haegeman, G.6
  • 24
    • 34347324118 scopus 로고    scopus 로고
    • Determinants of cell and genespecific transcriptional regulation by the glucocorticoid receptor
    • So AY, Chaivorapol C, Bolton EC, Li H, Yamamoto KR: Determinants of cell and genespecific transcriptional regulation by the glucocorticoid receptor. PLoS Genet 2007; 3:e94.
    • (2007) PLoS Genet , vol.3 , pp. e94
    • So, A.Y.1    Chaivorapol, C.2    Bolton, E.C.3    Li, H.4    Yamamoto, K.R.5
  • 25
    • 79953871100 scopus 로고    scopus 로고
    • Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor
    • Surjit M, Ganti KP, Mukherji A, Ye T, Hua G, Metzger D, Li M, Chambon P: Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor. Cell 2011; 145: 224-241.
    • (2011) Cell , vol.145 , pp. 224-241
    • Surjit, M.1    Ganti, K.P.2    Mukherji, A.3    Ye, T.4    Hua, G.5    Metzger, D.6    Li, M.7    Chambon, P.8
  • 26
    • 84870330189 scopus 로고    scopus 로고
    • Mechanisms of the anti-inflammatory effects of glucocorticoids: Genomic and nongenomic interference with mapk signaling pathways
    • Ayroldi E, Cannarile L, Migliorati G, Nocentini G, Delfino DV, Riccardi C: Mechanisms of the anti-inflammatory effects of glucocorticoids: genomic and nongenomic interference with MAPK signaling pathways. Faseb J 2012; 26: 4805-4820.
    • (2012) Faseb J , vol.26 , pp. 4805-4820
    • Ayroldi, E.1    Cannarile, L.2    Migliorati, G.3    Nocentini, G.4    Delfino, D.V.5    Riccardi, C.6
  • 28
    • 0034964627 scopus 로고    scopus 로고
    • Molecular identification and characterization of a and b forms of the glucocorticoid receptor
    • Yudt MR, Cidlowski JA: Molecular identification and characterization of A and B forms of the glucocorticoid receptor. Mol Endocrinol 2001; 15: 1093-1103.
    • (2001) Mol Endocrinol , vol.15 , pp. 1093-1103
    • Yudt, M.R.1    Cidlowski, J.A.2
  • 29
    • 53849143575 scopus 로고    scopus 로고
    • Tissue-specific glucocorticoid action: A family affair
    • Gross KL, Cidlowski JA: Tissue-specific glucocorticoid action: A family affair. Trends Endocrinol Metab 2008; 19: 331-339.
    • (2008) Trends Endocrinol Metab , vol.19 , pp. 331-339
    • Gross, K.L.1    Cidlowski, J.A.2
  • 30
    • 0029993518 scopus 로고    scopus 로고
    • The human glucocorticoid receptor β isoform. Expression, biochemical properties, and putative function
    • Oakley RH, Sar M, Cidlowski JA: The human glucocorticoid receptor β isoform. Expression, biochemical properties, and putative function. J Biol Chem 1996; 271: 9550-9559.
    • (1996) J Biol Chem , vol.271 , pp. 9550-9559
    • Oakley, R.H.1    Sar, M.2    Cidlowski, J.A.3
  • 31
    • 79952799756 scopus 로고    scopus 로고
    • Cellular processing of the glucocorticoid receptor gene and protein: New mechanisms for generating tissuespecific actions of glucocorticoids
    • Oakley RH, Cidlowski JA: Cellular processing of the glucocorticoid receptor gene and protein: new mechanisms for generating tissuespecific actions of glucocorticoids. J Biol Chem 2011; 286: 3177-3184.
    • (2011) J Biol Chem , vol.286 , pp. 3177-3184
    • Oakley, R.H.1    Cidlowski, J.A.2
  • 32
    • 0029056558 scopus 로고
    • Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans
    • Bamberger CM, Bamberger AM, de Castro M, Chrousos GP: Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans. J Clin Invest 1995; 95: 2435-2441.
    • (1995) J Clin Invest , vol.95 , pp. 2435-2441
    • Bamberger, C.M.1    Bamberger, A.M.2    De Castro, M.3    Chrousos, G.P.4
  • 33
    • 70349881524 scopus 로고    scopus 로고
    • Human glucocorticoid receptor isoform beta: Recent understanding of its potential implications in physiology and pathophysiology
    • Kino T, Su YA, Chrousos GP: Human glucocorticoid receptor isoform beta: recent understanding of its potential implications in physiology and pathophysiology. Cell Mol Life Sci 2009; 66: 3435-3448.
    • (2009) Cell Mol Life Sci. , vol.66 , pp. 3435-3448
    • Kino, T.1    Su, Y.A.2    Chrousos, G.P.3
  • 34
    • 33745625334 scopus 로고    scopus 로고
    • The physiology of human glucocorticoid receptor beta (hgrβ) and glucocorticoid resistance
    • Lewis-Tuffin LJ, Cidlowski JA: The physiology of human glucocorticoid receptor beta (hGRβ) and glucocorticoid resistance. Ann NY Acad Sci 2006; 1069: 1-9.
    • (2006) Ann NY Acad Sci , vol.1069 , pp. 1-9
    • Lewis-Tuffin, L.J.1    Cidlowski, J.A.2
  • 36
    • 77955430104 scopus 로고    scopus 로고
    • Role of ligand-dependent gr phosphorylation and half-life in determination of ligand-specific transcriptional activity
    • Avenant C, Ronacher K, Stubsrud E, Louw A, Hapgood JP: Role of ligand-dependent GR phosphorylation and half-life in determination of ligand-specific transcriptional activity. Mol Cell Endocrinol 2010; 327: 72-88.
    • (2010) Mol Cell Endocrinol , vol.327 , pp. 72-88
    • Avenant, C.1    Ronacher, K.2    Stubsrud, E.3    Louw, A.4    Hapgood, J.P.5
  • 37
    • 0037135596 scopus 로고    scopus 로고
    • Deciphering the phosphorylation 'code' of the glucocorticoid receptor in vivo
    • Wang Z, Frederick J, Garabedian MJ: Deciphering the phosphorylation 'code' of the glucocorticoid receptor in vivo. J Biol Chem 2002; 277: 26573-26580.
    • (2002) J Biol Chem , vol.277 , pp. 26573-26580
    • Wang, Z.1    Frederick, J.2    Garabedian, M.J.3
  • 38
    • 0030900729 scopus 로고    scopus 로고
    • Mouse glucocorticoid receptor phosphorylation status influences multiple functions of the receptor protein
    • Webster JC, Jewell CM, Bodwell JE, Munck A, Sar M, Cidlowski JA: Mouse glucocorticoid receptor phosphorylation status influences multiple functions of the receptor protein. J Biol Chem 1997; 272: 9287-9293.
    • (1997) J Biol Chem , vol.272 , pp. 9287-9293
    • Webster, J.C.1    Jewell, C.M.2    Bodwell, J.E.3    Munck, A.4    Sar, M.5    Cidlowski, J.A.6
  • 39
    • 22344458207 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase (mapk) is a key mediator in glucocorticoid-induced apoptosis of lymphoid cells: Correlation between p38 mapk activation and site-specific phosphorylation of the human glucocorticoid receptor at serine 211
    • Miller AL, Webb MS, Copik AJ, Wang Y, Johnson BH, Kumar R, Thompson EB: p38 mitogen-activated protein kinase (MAPK) is a key mediator in glucocorticoid-induced apoptosis of lymphoid cells: correlation between p38 MAPK activation and site-specific phosphorylation of the human glucocorticoid receptor at serine 211. Mol Endocrinol 2005; 19: 1569-1583.
    • (2005) Mol Endocrinol , vol.19 , pp. 1569-1583
    • Miller, A.L.1    Webb, M.S.2    Copik, A.J.3    Wang, Y.4    Johnson, B.H.5    Kumar, R.6    Thompson, E.B.7
  • 41
    • 57349115215 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3β-mediated serine phosphorylation of the human glucocorticoid receptor redirects gene expression profiles
    • Galliher-Beckley AJ, Williams JG, Collins JB, Cidlowski JA: Glycogen synthase kinase 3β-mediated serine phosphorylation of the human glucocorticoid receptor redirects gene expression profiles. Mol Cell Biol 2008; 28: 73097322.
    • (2008) Mol Cell Biol , vol.28 , pp. 73097322
    • Galliher-Beckley, A.J.1    Williams, J.G.2    Collins, J.B.3    Cidlowski, J.A.4
  • 42
    • 83255187892 scopus 로고    scopus 로고
    • Ligand-independent phosphorylation of the glucocorticoid receptor integrates cellular stress pathways with nuclear receptor signaling
    • Galliher-Beckley AJ, Williams JG, Cidlowski JA: Ligand-independent phosphorylation of the glucocorticoid receptor integrates cellular stress pathways with nuclear receptor signaling. Mol Cell Biol 2011; 31: 4663-4675.
    • (2011) Mol Cell Biol , vol.31 , pp. 4663-4675
    • Galliher-Beckley, A.J.1    Williams, J.G.2    Cidlowski, J.A.3
  • 43
    • 0035900780 scopus 로고    scopus 로고
    • Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids
    • Wallace AD, Cidlowski JA: Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids. J Biol Chem 2001; 276: 42714- 42721.
    • (2001) J Biol Chem , vol.276 , pp. 42714-42721
    • Wallace, A.D.1    Cidlowski, J.A.2
  • 45
    • 31344446119 scopus 로고    scopus 로고
    • Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables nf-κb suppression
    • Ito K, Yamamura S, Essilfie-Quaye S, Cosio B, Ito M, Barnes PJ, Adcock IM: Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression. J Exp Med 2006; 203: 7-13.
    • (2006) J Exp Med , vol.203 , pp. 7-13
    • Ito, K.1    Yamamura, S.2    Essilfie-Quaye, S.3    Cosio, B.4    Ito, M.5    Barnes, P.J.6    Adcock, I.M.7
  • 46
    • 80053238851 scopus 로고    scopus 로고
    • Peripheral clock regulates target-tissue glucocorticoid receptor transcriptional activity in a circadian fashion in man
    • Charmandari E, Chrousos GP, Lambrou GI, Pavlaki A, Koide H, Ng SS, Kino T: Peripheral CLOCK regulates target-tissue glucocorticoid receptor transcriptional activity in a circadian fashion in man. PLoS One 2011; 6:e25612.
    • (2011) PLoS One , vol.6 , pp. e25612
    • Charmandari, E.1    Chrousos, G.P.2    Lambrou, G.I.3    Pavlaki, A.4    Koide, H.5    Ng, S.S.6    Kino, T.7
  • 47
    • 33846661385 scopus 로고    scopus 로고
    • An inflammatory review of glucocorticoid actions in the cns
    • Sorrells SF, Sapolsky RM: An inflammatory review of glucocorticoid actions in the CNS. Brain Behav Immun 2007; 21: 259-272.
    • (2007) Brain Behav Immun , vol.21 , pp. 259-272
    • Sorrells, S.F.1    Sapolsky, R.M.2
  • 48
    • 0036920021 scopus 로고    scopus 로고
    • Stress-induced augmentation of immune function - The role of stress hormones, leukocyte trafficking, and cytokines
    • Dhabhar FS: Stress-induced augmentation of immune function - The role of stress hormones, leukocyte trafficking, and cytokines. Brain Behav Immun 2002; 16: 785-798.
    • (2002) Brain Behav Immun , vol.16 , pp. 785-798
    • Dhabhar, F.S.1
  • 49
    • 0033514465 scopus 로고    scopus 로고
    • Enhancing versus suppressive effects of stress hormones on skin immune function
    • Dhabhar FS, McEwen BS: Enhancing versus suppressive effects of stress hormones on skin immune function. Proc Natl Acad Sci USA 1999; 96: 1059-1064.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 1059-1064
    • Dhabhar, F.S.1    McEwen, B.S.2
  • 52
    • 36749094497 scopus 로고    scopus 로고
    • Stressor-specific alterations in corticosterone and immune responses in mice
    • Bowers SL, Bilbo SD, Dhabhar FS, Nelson RJ: Stressor-specific alterations in corticosterone and immune responses in mice. Brain Behav Immun 2008; 22: 105-113.
    • (2008) Brain Behav Immun , vol.22 , pp. 105-113
    • Bowers, S.L.1    Bilbo, S.D.2    Dhabhar, F.S.3    Nelson, R.J.4
  • 53
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O: Pathogen recognition and innate immunity. Cell 2006; 124: 783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 54
    • 32944477673 scopus 로고    scopus 로고
    • The evolution of adaptive immunity
    • Pancer Z, Cooper MD: The evolution of adaptive immunity. Annu Rev Immunol 2006; 24: 497-518.
    • (2006) Annu Rev Immunol , vol.24 , pp. 497-518
    • Pancer, Z.1    Cooper, M.D.2
  • 55
    • 34248372929 scopus 로고    scopus 로고
    • Macrophage glucocorticoid receptors regulate toll-like receptor 4-mediated inflammatory responses by selective inhibition of p38 map kinase
    • Bhattacharyya S, Brown DE, Brewer JA, Vogt SK, Muglia LJ: Macrophage glucocorticoid receptors regulate Toll-like receptor 4-mediated inflammatory responses by selective inhibition of p38 MAP kinase. Blood 2007; 109: 4313-4319.
    • (2007) Blood , vol.109 , pp. 4313-4319
    • Bhattacharyya, S.1    Brown, D.E.2    Brewer, J.A.3    Vogt, S.K.4    Muglia, L.J.5
  • 57
    • 33744477341 scopus 로고    scopus 로고
    • How corticosteroids control inflammation: Quintiles prize lecture 2005
    • Barnes PJ: How corticosteroids control inflammation: Quintiles Prize Lecture 2005. Br J Pharmacol 2006; 148: 245-254.
    • (2006) Br J Pharmacol , vol.148 , pp. 245-254
    • Barnes, P.J.1
  • 58
    • 12344252237 scopus 로고    scopus 로고
    • Ap-1 subunits: Quarrel and harmony among siblings
    • Hess J, Angel P, Schorpp-Kistner M: AP-1 subunits: quarrel and harmony among siblings. J Cell Sci 2004; 117(pt 25):5965-5973.
    • (2004) J Cell Sci. , vol.117 , pp. 5965-5973
    • Hess, J.1    Angel, P.2    Schorpp-Kistner, M.3
  • 59
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by erk, jnk, and p38 protein kinases
    • Johnson GL, Lapadat R: Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002; 298: 1911-1912.
    • (2002) Science , vol.298 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 61
    • 0030824266 scopus 로고    scopus 로고
    • A new function for the c-terminal zinc finger of the glucocorticoid receptor: Repression of rela transactivation
    • Liden J, Delaunay F, Rafter I, Gustafsson J, Okret S: A new function for the C-terminal zinc finger of the glucocorticoid receptor: repression of RelA transactivation. J Biol Chem 1997; 272: 21467-21472.
    • (1997) J Biol Chem , vol.272 , pp. 21467-21472
    • Liden, J.1    Delaunay, F.2    Rafter, I.3    Gustafsson, J.4    Okret, S.5
  • 62
    • 30444456366 scopus 로고    scopus 로고
    • The grip1:irf3 interaction as a target for glucocorticoid receptor-mediated immunosuppression
    • Reily MM, Pantoja C, Hu X, Chinenov Y, Rogatsky I: The GRIP1:IRF3 interaction as a target for glucocorticoid receptor-mediated immunosuppression. Embo J 2006; 25: 108-117.
    • (2006) Embo J , vol.25 , pp. 108-117
    • Reily, M.M.1    Pantoja, C.2    Hu, X.3    Chinenov, Y.4    Rogatsky, I.5
  • 63
    • 0034464826 scopus 로고    scopus 로고
    • Cbp (creb binding protein) integrates nf-κb (nuclear factor-κb) and glucocorticoid receptor physical interactions and antagonism
    • McKay LI, Cidlowski JA: CBP (CREB binding protein) integrates NF-κB (nuclear factor-κB) and glucocorticoid receptor physical interactions and antagonism. Mol Endocrinol 2000; 14: 1222-1234.
    • (2000) Mol Endocrinol , vol.14 , pp. 1222-1234
    • McKay, L.I.1    Cidlowski, J.A.2
  • 64
    • 0034665748 scopus 로고    scopus 로고
    • The glucocorticoid receptor inhibits nfκb by interfering with serine-2 phosphorylation of the rna polymerase ii carboxy-terminal domain
    • Nissen RM, Yamamoto KR: The glucocorticoid receptor inhibits NFκB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes Dev 2000; 14: 2314-2329.
    • (2000) Genes Dev , vol.14 , pp. 2314-2329
    • Nissen, R.M.1    Yamamoto, K.R.2
  • 66
    • 33845218654 scopus 로고    scopus 로고
    • Glucocorticoids regulate tristetraprolin synthesis and post transcriptionally regulate tumor necrosis factor alpha inflammatory signaling
    • Smoak K, Cidlowski JA: Glucocorticoids regulate tristetraprolin synthesis and posttranscriptionally regulate tumor necrosis factor alpha inflammatory signaling. Mol Cell Biol 2006; 26: 9126-9135.
    • (2006) Mol Cell Biol , vol.26 , pp. 9126-9135
    • Smoak, K.1    Cidlowski, J.A.2
  • 67
    • 8544255551 scopus 로고    scopus 로고
    • The tandem ccch zinc finger protein tristetraprolin and its relevance to cytokine mrna turnover and arthritis
    • Carrick DM, Lai WS, Blackshear PJ: The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis. Arthritis Res Ther 2004; 6: 248- 264.
    • (2004) Arthritis Res Ther , vol.6 , pp. 248-264
    • Carrick, D.M.1    Lai, W.S.2    Blackshear, P.J.3
  • 68
    • 0036625802 scopus 로고    scopus 로고
    • A hassle a day may keep the doctor away: Stress and the augmentation of immune function
    • Dhabhar FS: A hassle a day may keep the doctor away: stress and the augmentation of immune function. Integr Comp Biol 2002; 42: 556-564.
    • (2002) Integr Comp Biol , vol.42 , pp. 556-564
    • Dhabhar, F.S.1
  • 69
    • 34547902854 scopus 로고    scopus 로고
    • Glucocorticoids and the innate immune system: Crosstalk with the toll-like receptor signaling network
    • Chinenov Y, Rogatsky I: Glucocorticoids and the innate immune system: crosstalk with the toll-like receptor signaling network. Mol Cell Endocrinol 2007; 275: 30-42.
    • (2007) Mol Cell Endocrinol , vol.275 , pp. 30-42
    • Chinenov, Y.1    Rogatsky, I.2
  • 72
    • 2442679177 scopus 로고    scopus 로고
    • Glucocorticoids and tumor necrosis factor alpha cooperatively regulate tolllike receptor 2 gene expression
    • Hermoso MA, Matsuguchi T, Smoak K, Cidlowski JA: Glucocorticoids and tumor necrosis factor alpha cooperatively regulate Tolllike receptor 2 gene expression. Mol Cell Biol 2004; 24: 4743-4756.
    • (2004) Mol Cell Biol , vol.24 , pp. 4743-4756
    • Hermoso, M.A.1    Matsuguchi, T.2    Smoak, K.3    Cidlowski, J.A.4
  • 73
    • 0037053315 scopus 로고    scopus 로고
    • Glucocorticoids synergistically enhance nontypeable haemophilus influenzae -induced toll-like receptor 2 expression via a negative cross-talk with p38 map kinase
    • Shuto T, Imasato A, Jono H, Sakai A, Xu H, Watanabe T, Rixter DD, Kai H, Andalibi A, Linthicum F, et al: Glucocorticoids synergistically enhance nontypeable Haemophilus influenzae -induced Toll-like receptor 2 expression via a negative cross-talk with p38 MAP kinase. J Biol Chem 2002; 277: 17263-17270.
    • (2002) J Biol Chem , vol.277 , pp. 17263-17270
    • Shuto, T.1    Imasato, A.2    Jono, H.3    Sakai, A.4    Xu, H.5    Watanabe, T.6    Rixter, D.D.7    Kai, H.8    Andalibi, A.9    Linthicum, F.10
  • 75
    • 84864383684 scopus 로고    scopus 로고
    • Proinflammatory actions of glucocorticoids: Glucocorticoids and tnfα coregulate gene expression in vitro and in vivo
    • Lannan EA, Galliher-Beckley AJ, Scoltock AB, Cidlowski JA: Proinflammatory actions of glucocorticoids: glucocorticoids and TNFα coregulate gene expression in vitro and in vivo. Endocrinology 2012; 153: 3701-3712.
    • (2012) Endocrinology , vol.153 , pp. 3701-3712
    • Lannan, E.A.1    Galliher-Beckley, A.J.2    Scoltock, A.B.3    Cidlowski, J.A.4
  • 76
    • 55449093226 scopus 로고    scopus 로고
    • Regulatory network analyses reveal genome- wide potentiation of lif signaling by glucocorticoids and define an innate cell defense response
    • Langlais D, Couture C, Balsalobre A, Drouin J: Regulatory network analyses reveal genome- wide potentiation of LIF signaling by glucocorticoids and define an innate cell defense response. PLoS Genet 2008; 4:e1000224.
    • (2008) PLoS Genet , vol.4 , pp. e1000224
    • Langlais, D.1    Couture, C.2    Balsalobre, A.3    Drouin, J.4
  • 77
    • 80055069956 scopus 로고    scopus 로고
    • Glucocorticoids sensitize the innate immune system through regulation of the nlrp3 inflammasome
    • Busillo JM, Azzam KM, Cidlowski JA: Glucocorticoids sensitize the innate immune system through regulation of the NLRP3 inflammasome. J Biol Chem 2011; 286: 38703-38713.
    • (2011) J Biol Chem , vol.286 , pp. 38703-38713
    • Busillo, J.M.1    Azzam, K.M.2    Cidlowski, J.A.3
  • 78
    • 78649545971 scopus 로고    scopus 로고
    • Dexamethasone enhances atp-induced inflammatory responses in endothelial cells
    • Ding Y, Gao ZG, Jacobson KA, Suffredini AF: Dexamethasone enhances ATP-induced inflammatory responses in endothelial cells. J Pharmacol Exp Ther 2010; 335: 693-702.
    • (2010) J Pharmacol Exp Ther , vol.335 , pp. 693-702
    • Ding, Y.1    Gao, Z.G.2    Jacobson, K.A.3    Suffredini, A.F.4
  • 80
    • 75349101049 scopus 로고    scopus 로고
    • Familial glucocorticoid deficiency with a point mutation in the acth receptor: A case report
    • Kim CJ, Woo YJ, Kim GH, Yoo HW: Familial glucocorticoid deficiency with a point mutation in the ACTH receptor: A case report. J Korean Med Sci 2009; 24: 979-981.
    • (2009) J Korean Med Sci , vol.24 , pp. 979-981
    • Kim, C.J.1    Woo, Y.J.2    Kim, G.H.3    Yoo, H.W.4
  • 81
    • 79952116875 scopus 로고    scopus 로고
    • Sexually dimorphic actions of glucocorticoids provide a link to inflammatory diseases with gender differences in prevalence
    • Duma D, Collins JB, Chou JW, Cidlowski JA: Sexually dimorphic actions of glucocorticoids provide a link to inflammatory diseases with gender differences in prevalence. Sci Signal 2010; 3:ra74.
    • (2010) Sci Signal , vol.3 , pp. ra74
    • Duma, D.1    Collins, J.B.2    Chou, J.W.3    Cidlowski, J.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.