Regulatory network analyses reveal genome-wide potentiation of LIF signaling by glucocorticoids and define an innate cell defense response

PLoS Genetics

Volumn 4, Issue 10, 2008, Pages

  Langlais, David ^a   Couture, Catherine ^a   Balsalobre, Aurélio ^a   Drouin, Jacques ^a  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GLUCOCORTICOID; INTERLEUKIN 6; PROTEIN LIF; PROTEIN S 100; STAT3 PROTEIN; UNCLASSIFIED DRUG; ACUTE PHASE PROTEIN; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; LCN2 PROTEIN, MOUSE; LEUKEMIA INHIBITORY FACTOR; LIF PROTEIN, MOUSE; LIPOCALIN; ONCOPROTEIN; RECOMBINANT PROTEIN; STAT3 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA FINGERPRINTING; GENE CLUSTER; GENE CONTROL; GENE EXPRESSION; GENE SEQUENCE; GENE TARGETING; HYPOTHALAMUS HYPOPHYSIS SYSTEM; INNATE IMMUNITY; NONHUMAN; PROMOTER REGION; PROTEIN BINDING; SIGNAL TRANSDUCTION; ANIMAL; BINDING SITE; CELL LINE; DRUG EFFECT; FEEDBACK SYSTEM; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETICS; GENOME; HYPOPHYSIS ADRENAL SYSTEM; IMMUNOLOGY; METABOLISM; MOUSE; MULTIGENE FAMILY; PHYSIOLOGY;

ACUTE-PHASE PROTEINS; ANIMALS; BINDING SITES; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; DEXAMETHASONE; FEEDBACK, BIOCHEMICAL; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; GENOME; GLUCOCORTICOIDS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; IMMUNITY, NATURAL; LEUKEMIA INHIBITORY FACTOR; LIPOCALINS; MICE; MULTIGENE FAMILY; ONCOGENE PROTEINS; PITUITARY-ADRENAL SYSTEM; RECEPTORS, GLUCOCORTICOID; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 55449093226     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000224     Document Type: Article

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