Nanoparticulate iron(III) oxo-hydroxide delivers safe iron that is well absorbed and utilised in humans

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 10, Issue 8, 2014, Pages 1877-1886

  Pereira, Dora I A ^a   Bruggraber, Sylvaine F A ^a   Faria, Nuno ^a   Poots, Lynsey K ^a   Tagmount, Mani A ^b   Aslam, Mohamad F ^a   Frazer, David M ^c   Vulpe, Chris D ^b   Anderson, Gregory J ^c   Powell, Jonathan J ^a  

^a MRC HUMAN NUTRITION RESEARCH   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Bioavailability; Iron supplementation; Ligand modified fe(III) poly oxo hydroxide; Microbiota; Redox damage

Indexed keywords

BIOCHEMISTRY; IRON COMPOUNDS; SULFUR COMPOUNDS; TOXICITY;

BIOAVAILABILITY; GASTROINTESTINAL TRACT; INTESTINAL TOXICITY; MICROBIOTAS; MODIFIED FE; NUTRITIONAL DISORDERS; REDOX DAMAGE; RELATIVE BIOAVAILABILITY;

IRON;

ADIPIC ACID; FERRIC HYDROXIDE; FERROUS SULFATE; GLUCONIC ACID; IRON OXOHYDROXIDE NANOPARTICLE; NANOPARTICLE; SUCCINIC ACID; TARTARIC ACID; UNCLASSIFIED DRUG; FERRIC ION; IRON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG SOLUBILITY; DRUG UPTAKE; DRY POWDER; FEMALE; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VITRO STUDY; INTESTINE FLORA; INTESTINE MUCOSA; IRON ABSORPTION; IRON BLOOD LEVEL; IRON DEFICIENCY; IRON THERAPY; IRON TRANSPORT; MALE; MICROFLORA; MURINE MODEL; NONHUMAN; RANDOMIZED CONTROLLED TRIAL; RAT; SAFETY; ANEMIA, IRON-DEFICIENCY; ANIMAL; CACO 2 CELL LINE; CELL SURVIVAL; CHEMISTRY; HT 29 CELL LINE; INTESTINE ABSORPTION; METABOLISM;

ANEMIA, IRON-DEFICIENCY; ANIMALS; CACO-2 CELLS; CELL SURVIVAL; FERRIC COMPOUNDS; HT29 CELLS; HUMANS; INTESTINAL ABSORPTION; IRON; MALE; NANOPARTICLES; RATS;

EID: 84908574346     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2014.06.012     Document Type: Article

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