Oral ferrous sulphate leads to a marked increase in pro-oxidant nontransferrin-bound iron

European Journal of Clinical Investigation

Volumn 34, Issue 11, 2004, Pages 782-784

  Hutchinson, Carol ^a   Al Ashgar, W ^a   Liu, D Y ^a   Hider, R C ^a   Powell, J J ^a,b   Geissler, C A ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b Med Res Cncl Hum Nutr Research   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FERROUS SULFATE; IRON; TRANSFERRIN;

ADULT; ANEMIA; CLINICAL ARTICLE; DRUG EFFECT; FEMALE; HUMAN; IRON BLOOD LEVEL; LETTER; LIPID PEROXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; ADULT; ANEMIA; FEMALE; FERROUS COMPOUNDS; HUMANS; IRON; REACTIVE OXYGEN SPECIES; TRANSFERRIN;

EID: 8744254375     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2362.2004.01416.x     Document Type: Letter

References (8)

1. Kooistra MP, Kersting S, Gosriwatana S, Lu S, Nijhoff-Schutte J, Hider RC et al. Non-transferrin bound iron in the plasma of haemodialysis patients after intravenous iron saccharate infusion. Eur J Clin Invest 2002;32 (Suppl. 1):36-41.
2. Cighetti G, Duca L, Bortone L, Sala S, Nava I, Fiorelli G et al. Oxidative status and malondialdehyde in beta-thalassaemia patients. Eur J Clin Invest 2002;32 (Suppl. 1):55-60.
3. Roob JM, Khoschsorur G, Tiran A, Horina JH, Holzer H, Winklhofer-Roob BM. Vitamin E attenuates oxidative stress induced by intravenous iron in patients on hemodialysis. J Am Soc Nephrol 2000;11 (3):539-49.
4. Tuomainen T-P, Nyyssönen K, Porkkala-Sarataho E, Salonen R, Baumgartner JA, Geisser P et al. Oral supplementation with ferrous sulfate but not with non-ionic iron polymaltose complex increases the susceptibility of plasma lipoproteins to oxidation. Nutr Res 1999;19 (8):1121-32.
5. Kabat-Koperska J, Herdzik E, Safranow K, Myslak M, Domanski L, Rozanski J et al. Oral iron absorption test: should it be performed before starting treatment with ferrous preparations? Biol Trace Elem Res 2003;94 (1):87-94.
6. Gosriwatana I, Loreal O, Lu S, Brissot P, Porter J, Hider RC. Quantification of non-transferrin-bound iron in the presence of unsaturated transferrin. Anal Biochem 1999;273 (2):212-20.
7. Dainty JR, Roe MA, Teucher B, Eagles J, Fairweather-Tait SJ. Quantification of unlabelled non-haem iron absorption in human subjects: a pilot study. Br J Nutr 2003;90 (3):503-6.
8. Rooyakkers TM, Stroes ESG, Kooistra MP, van Faassen EE, Hider RC, Rabelink TJ et al. Ferric saccharate induces oxygen radical stress and endothelial dysfunction in vivo. Eur J Clin Invest 2002;32 (Suppl. 1):9-16.