Non-transferrin-bound iron in plasma following administration of oral iron drugs

BioMetals

Volumn 21, Issue 3, 2008, Pages 273-276

  Dresow, Bernd ^a   Petersen, Doerte ^a   Fischer, Roland ^a   Nielsen, Peter ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Iron medication; Non transferrin bound iron NTBI; Oral iron drugs; Risk factor; Transferrin saturation

Indexed keywords

FERROUS ION; IRON; TRANSFERRIN;

ADULT; ARTICLE; HUMAN; IRON DEFICIENCY ANEMIA; IRON STORAGE; NORMAL HUMAN; OXYGEN SATURATION; TRANSFERRIN BLOOD LEVEL;

ADMINISTRATION, ORAL; ANEMIA, IRON-DEFICIENCY; HUMANS; IRON; TRANSFERRIN;

EID: 42549148867     PISSN: 09660844     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10534-007-9116-5     Document Type: Article

References (21)

1. Bradley SJ, Gosriwitana I, Srichairatanakoof S, Hider RC, Porter JB (1997) Non-transferrin-bound iron induced by myeloablative chemotherapy. Br J Haematol 99:337-343
2. Breuer W, Herschko C, Cabantchik ZI (2000) The importance of non-transferrin-bound iron in disorders of iron metabolism. Transfus Sci 23:185-192
3. Dresow B, Albert C, Zimmermann I, Nielsen P (1995) Ethane exhalation and Vitamin-E/ubiquinol-status as markers of lipid peroxidation in ferrocene iron-loaded rats. Hepatology 21:1099-1105
4. Dürken M, Nielsen P, Knobel S, Finckh B, Herrnring C, Dresow B, Kohischütter B, Stockschläger M, Krüger WH, Kohlschütter A, Zander AR (1997) Nontransferrin-bound iron in serum of patients receiving bone marrow transplantation. Free Radical Biol Med 22:1159-1163
5. Erichsen K, Ulvik RJ, Grimstad T, Berstad A, Berge RK, Hausken T (2005) Effects of ferrous sulphate and non-ionic iron-polymaltose complex on markers of oxidative tissue damage in patients with inflammatory bowel disease. Aliment Pharmacol Ther 22:831-838
6. Esposito BP, Breuer W, Sirankapracha P, Pootrakul P, Hershko C, Cabantchik ZI (2003) Labile plasma iron in iron overload: redox activity and susceptibility to chelation. Blood 102:2670-2677
7. Gabbe EE, Heinrich HC, Icagic F (1982) Proposal for the standardization of the serum unsaturated iron binding capacity assay, and results in groups of subjects with normal iron stores and with prelatent, latent, and manifest iron deficiency. Clin Chim Acta 119:51-63
8. Gosriwatana I, Loréal O, Lu S, Brissot P, Porter J, Hider RC (1999) Quantification of non-transferrin-bound iron in the presence of unsaturated transferrin. Anal Biochem 273:212-220
9. Gutteridge JMC, Rowley DA, Griffiths E, Halliwell B (1985) Low-molecular-weight iron complexes and oxygen radical reactions in idiopathic haemochromatosis. Clin Sci 68:463-467
10. Halliwell B, Gutteridge JMC (1986) Oxygen, free radicals and iron in relation to biology and medicine: some problems and concepts. Arch Biochem Biophys 246:501-514
11. Halliwell B, Gutteridge JMC (1990) Role of free radicals and catalytic metal ions in human disease: an overview. Meth Enzymol 186:1-85
12. Hershko C, Graham G, Bates GW, Rachmilewitz EA (1978) Non-specific serum iron in thalassaemia: an abnormal serum iron fraction of potential toxicity. Br J Haematol 40:255-263
13. Lachili B, Hininger I, Faure H, Arnaud J, Richard MJ, Favier A, Roussel AM (2001) Increased lipid peroxidation in pregnant women after iron and vitamin C supplementation. Biol Trace Element Res 83:103-110
14. Lee DH, Liu DY, Jakobs DR, Shin H-R, Song K, Lee IK, Kim B, Hider RC (2006) Common presence of non-transferrin-bound iron among patients with type 2 diabetes. Diabetes Care 29:1090-1095
15. Nielsen P, Gabbe EE, Fischer R, Heinrich HC (1994) Bioavailability of iron from oral ferric polymaltose in humans. Arzneim Forsch 44:743-748
16. Rehema A, Zilmer K, Klaar U, Karro H, Kullisaar T, Zilmer M (2004) Ferrous iron administration during pregnancy and adaptional oxidative stress (pilot study). Medicina 40:547-552
17. Roob JM, Khoschsorur G, Tiran A, Horina JH, Holzer H, Winkelhofer-Roob BM (2000) Vitamin E attenuates oxidative stress induced by intravenous iron in patients on hemodialysis. J Am Soc Nephrol 11:539-549
18. Scheiber-Mojdehkar B, Lutzky B, Schaufler R, Sturm B, Goldenberg H (2004) Non-transferrin-bound iron in the serum of hemodialysis patients who receive ferric sacharate: no correlation to peroxide generation. J Am Soc Nephrol 15:1648-1655
19. Schümann K, Kroll S, Weiss G, Frank J, Biesalski HK, Daniel H, Friel J, Solomons NW (2005) Monitoring of hematological, inflammatory and oxidative reactions to acute oral iron exposure in human volunteers: preliminary screening for selection of potentially-responsive biomarkers. Toxicology 212:10-23
20. Singh S, Hider RC, Porter JB (1990) A direct method for quantitation of non-transferrin-bound iron. Anal Biochem 186:320-323
21. van Campenhout A, van Campenhout C, Lagrow A, Manuel-y-Keenoy B (2007) Iron-induced oxidative stress in haemodialysis patients: a pilot study on the impact of diabetes. Biometals online