-
1
-
-
84867744660
-
Genetic variation in metabolic phenotypes: study designs and applications
-
Suhre K., Gieger C. Genetic variation in metabolic phenotypes: study designs and applications. Nat. Rev. Genet. 2012, 13:759-769.
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 759-769
-
-
Suhre, K.1
Gieger, C.2
-
3
-
-
42349112088
-
Genome-wide association studies for complex traits: consensus, uncertainty and challenges
-
McCarthy M.I., Abecasis G.R., Cardon L.R., Goldstein D.B., Little J., Ioannidis J.P., Hirschhorn J.N. Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat. Rev. Genet. 2008, 9:356-369.
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 356-369
-
-
McCarthy, M.I.1
Abecasis, G.R.2
Cardon, L.R.3
Goldstein, D.B.4
Little, J.5
Ioannidis, J.P.6
Hirschhorn, J.N.7
-
4
-
-
58149347486
-
Genome-wide association studies: potential next steps on a genetic journey
-
McCarthy M.I., Hirschhorn J.N. Genome-wide association studies: potential next steps on a genetic journey. Hum. Mol. Genet. 2008, 17:R156-R165.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. R156-R165
-
-
McCarthy, M.I.1
Hirschhorn, J.N.2
-
5
-
-
58149335215
-
Genome-wide association studies: past, present and future
-
McCarthy M.I., Hirschhorn J.N. Genome-wide association studies: past, present and future. Hum. Mol. Genet. 2008, 17:R100-R101.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. R100-R101
-
-
McCarthy, M.I.1
Hirschhorn, J.N.2
-
6
-
-
84867129109
-
Functional evaluation of genetic variation in complex human traits
-
Peters D.T., Musunuru K. Functional evaluation of genetic variation in complex human traits. Hum. Mol. Genet. 2012, 21:R18-R23.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. R18-R23
-
-
Peters, D.T.1
Musunuru, K.2
-
7
-
-
84858783318
-
Finding genes and variants for lipid levels after genome-wide association analysis
-
Willer C.J., Mohlke K.L. Finding genes and variants for lipid levels after genome-wide association analysis. Curr. Opin. Lipidol. 2012, 23:98-103.
-
(2012)
Curr. Opin. Lipidol.
, vol.23
, pp. 98-103
-
-
Willer, C.J.1
Mohlke, K.L.2
-
8
-
-
38649132270
-
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
-
Kathiresan S., Melander O., Guiducci C., Surti A., Burtt N.P., Rieder M.J., Cooper G.M., Roos C., Voight B.F., Havulinna A.S., Wahlstrand B., Hedner T., Corella D., Tai E.S., Ordovas J.M., Berglund G., Vartiainen E., Jousilahti P., Hedblad B., Taskinen M.R., Newton-Cheh C., Salomaa V., Peltonen L., Groop L., Altshuler D.M., Orho-Melander M. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat. Genet. 2008, 40:189-197.
-
(2008)
Nat. Genet.
, vol.40
, pp. 189-197
-
-
Kathiresan, S.1
Melander, O.2
Guiducci, C.3
Surti, A.4
Burtt, N.P.5
Rieder, M.J.6
Cooper, G.M.7
Roos, C.8
Voight, B.F.9
Havulinna, A.S.10
Wahlstrand, B.11
Hedner, T.12
Corella, D.13
Tai, E.S.14
Ordovas, J.M.15
Berglund, G.16
Vartiainen, E.17
Jousilahti, P.18
Hedblad, B.19
Taskinen, M.R.20
Newton-Cheh, C.21
Salomaa, V.22
Peltonen, L.23
Groop, L.24
Altshuler, D.M.25
Orho-Melander, M.26
more..
-
9
-
-
38649125868
-
Newly identified loci that influence lipid concentrations and risk of coronary artery disease
-
Willer C.J., Sanna S., Jackson A.U., Scuteri A., Bonnycastle L.L., Clarke R., Heath S.C., Timpson N.J., Najjar S.S., Stringham H.M., Strait J., Duren W.L., Maschio A., Busonero F., Mulas A., Albai G., Swift A.J., Morken M.A., Narisu N., Bennett D., Parish S., Shen H., Galan P., Meneton P., Hercberg S., Zelenika D., Chen W.M., Li Y., Scott L.J., Scheet P.A., Sundvall J., Watanabe R.M., Nagaraja R., Ebrahim S., Lawlor D.A., Ben-Shlomo Y., Davey-Smith G., Shuldiner A.R., Collins R., Bergman R.N., Uda M., Tuomilehto J., Cao A., Collins F.S., Lakatta E., Lathrop G.M., Boehnke M., Schlessinger D., Mohlke K.L., Abecasis G.R. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat. Genet. 2008, 40:161-169.
-
(2008)
Nat. Genet.
, vol.40
, pp. 161-169
-
-
Willer, C.J.1
Sanna, S.2
Jackson, A.U.3
Scuteri, A.4
Bonnycastle, L.L.5
Clarke, R.6
Heath, S.C.7
Timpson, N.J.8
Najjar, S.S.9
Stringham, H.M.10
Strait, J.11
Duren, W.L.12
Maschio, A.13
Busonero, F.14
Mulas, A.15
Albai, G.16
Swift, A.J.17
Morken, M.A.18
Narisu, N.19
Bennett, D.20
Parish, S.21
Shen, H.22
Galan, P.23
Meneton, P.24
Hercberg, S.25
Zelenika, D.26
Chen, W.M.27
Li, Y.28
Scott, L.J.29
Scheet, P.A.30
Sundvall, J.31
Watanabe, R.M.32
Nagaraja, R.33
Ebrahim, S.34
Lawlor, D.A.35
Ben-Shlomo, Y.36
Davey-Smith, G.37
Shuldiner, A.R.38
Collins, R.39
Bergman, R.N.40
Uda, M.41
Tuomilehto, J.42
Cao, A.43
Collins, F.S.44
Lakatta, E.45
Lathrop, G.M.46
Boehnke, M.47
Schlessinger, D.48
Mohlke, K.L.49
Abecasis, G.R.50
more..
-
10
-
-
54249088172
-
Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations
-
Orho-Melander M., Melander O., Guiducci C., Perez-Martinez P., Corella D., Roos C., Tewhey R., Rieder M.J., Hall J., Abecasis G., Tai E.S., Welch C., Arnett D.K., Lyssenko V., Lindholm E., Saxena R., de Bakker P.I., Burtt N., Voight B.F., Hirschhorn J.N., Tucker K.L., Hedner T., Tuomi T., Isomaa B., Eriksson K.F., Taskinen M.R., Wahlstrand B., Hughes T.E., Parnell L.D., Lai C.Q., Berglund G., Peltonen L., Vartiainen E., Jousilahti P., Havulinna A.S., Salomaa V., Nilsson P., Groop L., Altshuler D., Ordovas J.M., Kathiresan S. Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations. Diabetes 2008, 57:3112-3121.
-
(2008)
Diabetes
, vol.57
, pp. 3112-3121
-
-
Orho-Melander, M.1
Melander, O.2
Guiducci, C.3
Perez-Martinez, P.4
Corella, D.5
Roos, C.6
Tewhey, R.7
Rieder, M.J.8
Hall, J.9
Abecasis, G.10
Tai, E.S.11
Welch, C.12
Arnett, D.K.13
Lyssenko, V.14
Lindholm, E.15
Saxena, R.16
de Bakker, P.I.17
Burtt, N.18
Voight, B.F.19
Hirschhorn, J.N.20
Tucker, K.L.21
Hedner, T.22
Tuomi, T.23
Isomaa, B.24
Eriksson, K.F.25
Taskinen, M.R.26
Wahlstrand, B.27
Hughes, T.E.28
Parnell, L.D.29
Lai, C.Q.30
Berglund, G.31
Peltonen, L.32
Vartiainen, E.33
Jousilahti, P.34
Havulinna, A.S.35
Salomaa, V.36
Nilsson, P.37
Groop, L.38
Altshuler, D.39
Ordovas, J.M.40
Kathiresan, S.41
more..
-
11
-
-
79960108840
-
Triglyceride response to an intensive lifestyle intervention is enhanced in carriers of the GCKR Pro446Leu polymorphism
-
Pollin T.I., Jablonski K.A., McAteer J.B., Saxena R., Kathiresan S., Kahn S.E., Goldberg R.B., Altshuler D., Florez J.C. Triglyceride response to an intensive lifestyle intervention is enhanced in carriers of the GCKR Pro446Leu polymorphism. J. Clin. Endocrinol. Metab. 2011, 96:E1142-E1147.
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
, pp. E1142-E1147
-
-
Pollin, T.I.1
Jablonski, K.A.2
McAteer, J.B.3
Saxena, R.4
Kathiresan, S.5
Kahn, S.E.6
Goldberg, R.B.7
Altshuler, D.8
Florez, J.C.9
-
12
-
-
84855425880
-
Correlation of rare coding variants in the gene encoding human glucokinase regulatory protein with phenotypic, cellular, and kinetic outcomes
-
Rees M.G., Ng D., Ruppert S., Turner C., Beer N.L., Swift A.J., Morken M.A., Below J.E., Blech I., Mullikin J.C., McCarthy M.I., Biesecker L.G., Gloyn A.L., Collins F.S. Correlation of rare coding variants in the gene encoding human glucokinase regulatory protein with phenotypic, cellular, and kinetic outcomes. J. Clin. Invest. 2012, 122:205-217.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 205-217
-
-
Rees, M.G.1
Ng, D.2
Ruppert, S.3
Turner, C.4
Beer, N.L.5
Swift, A.J.6
Morken, M.A.7
Below, J.E.8
Blech, I.9
Mullikin, J.C.10
McCarthy, M.I.11
Biesecker, L.G.12
Gloyn, A.L.13
Collins, F.S.14
-
13
-
-
38649084407
-
Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides
-
Kooner J.S., Chambers J.C., Aguilar-Salinas C.A., Hinds D.A., Hyde C.L., Warnes G.R., Gomez Perez F.J., Frazer K.A., Elliott P., Scott J., Milos P.M., Cox D.R., Thompson J.F. Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides. Nat. Genet. 2008, 40:149-151.
-
(2008)
Nat. Genet.
, vol.40
, pp. 149-151
-
-
Kooner, J.S.1
Chambers, J.C.2
Aguilar-Salinas, C.A.3
Hinds, D.A.4
Hyde, C.L.5
Warnes, G.R.6
Gomez Perez, F.J.7
Frazer, K.A.8
Elliott, P.9
Scott, J.10
Milos, P.M.11
Cox, D.R.12
Thompson, J.F.13
-
14
-
-
58149163149
-
Common variants at 30 loci contribute to polygenic dyslipidemia
-
Kathiresan S., Willer C.J., Peloso G.M., Demissie S., Musunuru K., Schadt E.E., Kaplan L., Bennett D., Li Y., Tanaka T., Voight B.F., Bonnycastle L.L., Jackson A.U., Crawford G., Surti A., Guiducci C., Burtt N.P., Parish S., Clarke R., Zelenika D., Kubalanza K.A., Morken M.A., Scott L.J., Stringham H.M., Galan P., Swift A.J., Kuusisto J., Bergman R.N., Sundvall J., Laakso M., Ferrucci L., Scheet P., Sanna S., Uda M., Yang Q., Lunetta K.L., Dupuis J., de Bakker P.I., O'Donnell C.J., Chambers J.C., Kooner J.S., Hercberg S., Meneton P., Lakatta E.G., Scuteri A., Schlessinger D., Tuomilehto J., Collins F.S., Groop L., Altshuler D., Collins R., Lathrop G.M., Melander O., Salomaa V., Peltonen L., Orho-Melander M., Ordovas J.M., Boehnke M., Abecasis G.R., Mohlke K.L., Cupples L.A. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat. Genet. 2009, 41:56-65.
-
(2009)
Nat. Genet.
, vol.41
, pp. 56-65
-
-
Kathiresan, S.1
Willer, C.J.2
Peloso, G.M.3
Demissie, S.4
Musunuru, K.5
Schadt, E.E.6
Kaplan, L.7
Bennett, D.8
Li, Y.9
Tanaka, T.10
Voight, B.F.11
Bonnycastle, L.L.12
Jackson, A.U.13
Crawford, G.14
Surti, A.15
Guiducci, C.16
Burtt, N.P.17
Parish, S.18
Clarke, R.19
Zelenika, D.20
Kubalanza, K.A.21
Morken, M.A.22
Scott, L.J.23
Stringham, H.M.24
Galan, P.25
Swift, A.J.26
Kuusisto, J.27
Bergman, R.N.28
Sundvall, J.29
Laakso, M.30
Ferrucci, L.31
Scheet, P.32
Sanna, S.33
Uda, M.34
Yang, Q.35
Lunetta, K.L.36
Dupuis, J.37
de Bakker, P.I.38
O'Donnell, C.J.39
Chambers, J.C.40
Kooner, J.S.41
Hercberg, S.42
Meneton, P.43
Lakatta, E.G.44
Scuteri, A.45
Schlessinger, D.46
Tuomilehto, J.47
Collins, F.S.48
Groop, L.49
Altshuler, D.50
Collins, R.51
Lathrop, G.M.52
Melander, O.53
Salomaa, V.54
Peltonen, L.55
Orho-Melander, M.56
Ordovas, J.M.57
Boehnke, M.58
Abecasis, G.R.59
Mohlke, K.L.60
Cupples, L.A.61
more..
-
15
-
-
84887099827
-
Discovery and refinement of loci associated with lipid levels
-
C.Global Lipids Genetics, Willer C.J., Schmidt E.M., Sengupta S., Peloso G.M., Gustafsson S., Kanoni S., Ganna A., Chen J., Buchkovich M.L., Mora S., Beckmann J.S., Bragg-Gresham J.L., Chang H.Y., Demirkan A., Den Hertog H.M., Do R., Donnelly L.A., Ehret G.B., Esko T., Feitosa M.F., Ferreira T., Fischer K., Fontanillas P., Fraser R.M., Freitag D.F., Gurdasani D., Heikkila K., Hypponen E., Isaacs A., Jackson A.U., Johansson A., Johnson T., Kaakinen M., Kettunen J., Kleber M.E., Li X., Luan J., Lyytikainen L.P., Magnusson P.K., Mangino M., Mihailov E., Montasser M.E., Muller-Nurasyid M., Nolte I.M., O'Connell J.R., Palmer C.D., Perola M., Petersen A.K., Sanna S., Saxena R., S.K.Service, Shah S., Shungin D., Sidore C., Song C., Strawbridge R.J., Surakka I., Tanaka T., Teslovich T.M., Thorleifsson G., Van den Herik E.G., Voight B.F., Volcik K.A., Waite L.L., Wong A., Wu Y., Zhang W., Absher D., Asiki G., Barroso I., Been L.F., Bolton J.L., Bonnycastle L.L., Brambilla P., Burnett M.S., Cesana G., Dimitriou M., Doney A.S., Doring A., Elliott P., Epstein S.E., Eyjolfsson G.I., Gigante B., Goodarzi M.O., Grallert H., Gravito M.L., Groves C.J., Hallmans G., Hartikainen A.L., Hayward C., Hernandez D., Hicks A.A., Holm H., Hung Y.J., Illig T., Jones M.R., Kaleebu P., Kastelein J.J., Khaw K.T., Kim E., Klopp N., Komulainen P., Kumari M., Langenberg C., Lehtimaki T., Lin S.Y., Lindstrom J., Loos R.J., Mach F., McArdle W.L., Meisinger C., Mitchell B.D., Muller G., Nagaraja R., Narisu N., Nieminen T.V., Nsubuga R.N., Olafsson I., Ong K.K., Palotie A., Papamarkou T., Pomilla C., Pouta A., Rader D.J., Reilly M.P., Ridker P.M., Rivadeneira F., Rudan I., Ruokonen A., Samani N., Scharnagl H., Seeley J., Silander K., Stancakova A., Stirrups K., Swift A.J., Tiret L., Uitterlinden A.G., van Pelt L.J., Vedantam S., Wainwright N., Wijmenga C., Wild S.H., Willemsen G., Wilsgaard T., Wilson J.F., Young E.H., Zhao J.H., Adair L.S., Arveiler D., Assimes T.L., Bandinelli S., Bennett F., Bochud M., Boehm B.O., Boomsma D.I., Borecki I.B., Bornstein S.R., Bovet P., Burnier M., Campbell H., Chakravarti A., Chambers J.C., Chen Y.D., Collins F.S., Cooper R.S., Danesh J., Dedoussis G., de Faire U., Feranil A.B., Ferrieres J., Ferrucci L., Freimer N.B., Gieger C., Groop L.C., Gudnason V., Gyllensten U., Hamsten A., Harris T.B., Hingorani A., Hirschhorn J.N., Hofman A., Hovingh G.K., Hsiung C.A., Humphries S.E., Hunt S.C., Hveem K., Iribarren C., Jarvelin M.R., Jula A., Kahonen M., Kaprio J., Kesaniemi A., Kivimaki M., Kooner J.S., Koudstaal P.J., Krauss R.M., Kuh D., Kuusisto J., Kyvik K.O., Laakso M., Lakka T.A., Lind L., Lindgren C.M., Martin N.G., Marz W., McCarthy M.I., McKenzie C.A., Meneton P., Metspalu A., Moilanen L., Morris A.D., Munroe P.B., Njolstad I., Pedersen N.L., Power C., Pramstaller P.P., Price J.F., Psaty B.M., Quertermous T., Rauramaa R., Saleheen D., Salomaa V., Sanghera D.K., Saramies J., Schwarz P.E., Sheu W.H., Shuldiner A.R., Siegbahn A., Spector T.D., Stefansson K., Strachan D.P., Tayo B.O., Tremoli E., Tuomilehto J., Uusitupa M., van Duijn C.M., Vollenweider P., Wallentin L., Wareham N.J., Whitfield J.B., Wolffenbuttel B.H., Ordovas J.M., Boerwinkle E., Palmer C.N., Thorsteinsdottir U., Chasman D.I., Rotter J.I., Franks P.W., Ripatti S., Cupples L.A., Sandhu M.S., Rich S.S., Boehnke M., Deloukas P., Kathiresan S., Mohlke K.L., Ingelsson E., Abecasis G.R. Discovery and refinement of loci associated with lipid levels. Nat. Genet. 2013, 45:1274-1283.
-
(2013)
Nat. Genet.
, vol.45
, pp. 1274-1283
-
-
Willer, C.J.1
Sengupta, S.2
Gustafsson, S.3
Ganna, A.4
Buchkovich, M.L.5
Beckmann, J.S.6
Chang, H.Y.7
Den Hertog, H.M.8
Donnelly, L.A.9
Esko, T.10
Ferreira, T.11
Fontanillas, P.12
Freitag, D.F.13
Heikkila, K.14
Isaacs, A.15
Johansson, A.16
Kaakinen, M.17
Kleber, M.E.18
Luan, J.19
Magnusson, P.K.20
Mihailov, E.21
Muller-Nurasyid, M.22
O'Connell, J.R.23
Perola, M.24
Sanna, S.25
Service, S.K.26
Shungin, D.27
Song, C.28
Surakka, I.29
Teslovich, T.M.30
Van den Herik, E.G.31
Volcik, K.A.32
Wong, A.33
Zhang, W.34
Asiki, G.35
Been, L.F.36
Bonnycastle, L.L.37
Burnett, M.S.38
Dimitriou, M.39
Doring, A.40
Epstein, S.E.41
Gigante, B.42
Grallert, H.43
Groves, C.J.44
Hartikainen, A.L.45
Hernandez, D.46
Holm, H.47
Illig, T.48
Kaleebu, P.49
Schmidt, E.M.50
Peloso, G.M.51
Kanoni, S.52
Chen, J.53
Mora, S.54
Bragg-Gresham, J.L.55
Demirkan, A.56
Do, R.57
Ehret, G.B.58
Feitosa, M.F.59
Fischer, K.60
Fraser, R.M.61
Gurdasani, D.62
Hypponen, E.63
Jackson, A.U.64
Johnson, T.65
Kettunen, J.66
Li, X.67
Lyytikainen, L.P.68
Mangino, M.69
Montasser, M.E.70
Nolte, I.M.71
Palmer, C.D.72
Petersen, A.K.73
Saxena, R.74
Shah, S.75
Sidore, C.76
Strawbridge, R.J.77
Tanaka, T.78
Thorleifsson, G.79
Voight, B.F.80
Waite, L.L.81
Wu, Y.82
Absher, D.83
Barroso, I.84
Bolton, J.L.85
Brambilla, P.86
Cesana, G.87
Doney, A.S.88
Elliott, P.89
Eyjolfsson, G.I.90
Goodarzi, M.O.91
Gravito, M.L.92
Hallmans, G.93
Hayward, C.94
Hicks, A.A.95
Hung, Y.J.96
Jones, M.R.97
Kastelein, J.J.98
more..
-
16
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
Teslovich T.M., Musunuru K., Smith A.V., Edmondson A.C., Stylianou I.M., Koseki M., Pirruccello J.P., Ripatti S., Chasman D.I., Willer C.J., Johansen C.T., Fouchier S.W., Isaacs A., Peloso G.M., Barbalic M., Ricketts S.L., Bis J.C., Aulchenko Y.S., Thorleifsson G., Feitosa M.F., Chambers J., Orho-Melander M., Melander O., Johnson T., Li X., Guo X., Li M., Shin Cho Y., Jin Go M., Jin Kim Y., Lee J.Y., Park T., Kim K., Sim X., Twee-Hee Ong R., Croteau-Chonka D.C., Lange L.A., Smith J.D., Song K., Hua Zhao J., Yuan X., Luan J., Lamina C., Ziegler A., Zhang W., Zee R.Y., Wright A.F., Witteman J.C., Wilson J.F., Willemsen G., Wichmann H.E., Whitfield J.B., Waterworth D.M., Wareham N.J., Waeber G., Vollenweider P., Voight B.F., Vitart V., Uitterlinden A.G., Uda M., Tuomilehto J., Thompson J.R., Tanaka T., Surakka I., Stringham H.M., Spector T.D., Soranzo N., Smit J.H., Sinisalo J., Silander K., Sijbrands E.J., Scuteri A., Scott J., Schlessinger D., Sanna S., Salomaa V., Saharinen J., Sabatti C., Ruokonen A., Rudan I., Rose L.M., Roberts R., Rieder M., Psaty B.M., Pramstaller P.P., Pichler I., Perola M., Penninx B.W., Pedersen N.L., Pattaro C., Parker A.N., Pare G., Oostra B.A., O'Donnell C.J., Nieminen M.S., Nickerson D.A., Montgomery G.W., Meitinger T., McPherson R., McCarthy M.I., McArdle W., Masson D., Martin N.G., Marroni F., Mangino M., Magnusson P.K., Lucas G., Luben R., Loos R.J., Lokki M.L., Lettre G., Langenberg C., Launer L.J., Lakatta E.G., Laaksonen R., Kyvik K.O., Kronenberg F., Konig I.R., Khaw K.T., Kaprio J., Kaplan L.M., Johansson A., Jarvelin M.R., Janssens A.C., Ingelsson E., Igl W., Kees Hovingh G., Hottenga J.J., Hofman A., Hicks A.A., Hengstenberg C., Heid I.M., Hayward C., Havulinna A.S., Hastie N.D., Harris T.B., Haritunians T., Hall A.S., Gyllensten U., Guiducci C., Groop L.C., Gonzalez E., Gieger C., Freimer N.B., Ferrucci L., Erdmann J., Elliott P., Ejebe K.G., Doring A., Dominiczak A.F., Demissie S., Deloukas P., de Geus E.J., de Faire U., Crawford G., Collins F.S., Chen Y.D., Caulfield M.J., Campbell H., Burtt N.P., Bonnycastle L.L., Boomsma D.I., Boekholdt S.M., Bergman R.N., Barroso I., Bandinelli S., Ballantyne C.M., Assimes T.L., Quertermous T., Altshuler D., Seielstad M., Wong T.Y., Tai E.S., Feranil A.B., Kuzawa C.W., Adair L.S., Taylor H.A., Borecki I.B., Gabriel S.B., Wilson J.G., Holm H., Thorsteinsdottir U., Gudnason V., Krauss R.M., Mohlke K.L., Ordovas J.M., Munroe P.B., Kooner J.S., Tall A.R., Hegele R.A., Kastelein J.J., Schadt E.E., Rotter J.I., Boerwinkle E., Strachan D.P., Mooser V., Stefansson K., Reilly M.P., Samani N.J., Schunkert H., Cupples L.A., Sandhu M.S., Ridker P.M., Rader D.J., van Duijn C.M., Peltonen L., Abecasis G.R., Boehnke M., Kathiresan S. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010, 466:707-713.
-
(2010)
Nature
, vol.466
, pp. 707-713
-
-
Teslovich, T.M.1
Musunuru, K.2
Smith, A.V.3
Edmondson, A.C.4
Stylianou, I.M.5
Koseki, M.6
Pirruccello, J.P.7
Ripatti, S.8
Chasman, D.I.9
Willer, C.J.10
Johansen, C.T.11
Fouchier, S.W.12
Isaacs, A.13
Peloso, G.M.14
Barbalic, M.15
Ricketts, S.L.16
Bis, J.C.17
Aulchenko, Y.S.18
Thorleifsson, G.19
Feitosa, M.F.20
Chambers, J.21
Orho-Melander, M.22
Melander, O.23
Johnson, T.24
Li, X.25
Guo, X.26
Li, M.27
Shin Cho, Y.28
Jin Go, M.29
Jin Kim, Y.30
Lee, J.Y.31
Park, T.32
Kim, K.33
Sim, X.34
Twee-Hee Ong, R.35
Croteau-Chonka, D.C.36
Lange, L.A.37
Smith, J.D.38
Song, K.39
Hua Zhao, J.40
Yuan, X.41
Luan, J.42
Lamina, C.43
Ziegler, A.44
Zhang, W.45
Zee, R.Y.46
Wright, A.F.47
Witteman, J.C.48
Wilson, J.F.49
Willemsen, G.50
Wichmann, H.E.51
Whitfield, J.B.52
Waterworth, D.M.53
Wareham, N.J.54
Waeber, G.55
Vollenweider, P.56
Voight, B.F.57
Vitart, V.58
Uitterlinden, A.G.59
Uda, M.60
Tuomilehto, J.61
Thompson, J.R.62
Tanaka, T.63
Surakka, I.64
Stringham, H.M.65
Spector, T.D.66
Soranzo, N.67
Smit, J.H.68
Sinisalo, J.69
Silander, K.70
Sijbrands, E.J.71
Scuteri, A.72
Scott, J.73
Schlessinger, D.74
Sanna, S.75
Salomaa, V.76
Saharinen, J.77
Sabatti, C.78
Ruokonen, A.79
Rudan, I.80
Rose, L.M.81
Roberts, R.82
Rieder, M.83
Psaty, B.M.84
Pramstaller, P.P.85
Pichler, I.86
Perola, M.87
Penninx, B.W.88
Pedersen, N.L.89
Pattaro, C.90
Parker, A.N.91
Pare, G.92
Oostra, B.A.93
O'Donnell, C.J.94
Nieminen, M.S.95
Nickerson, D.A.96
Montgomery, G.W.97
Meitinger, T.98
McPherson, R.99
more..
-
17
-
-
78149245489
-
Genetic variants influencing circulating lipid levels and risk of coronary artery disease
-
Waterworth D.M., Ricketts S.L., Song K., Chen L., Zhao J.H., Ripatti S., Aulchenko Y.S., Zhang W., Yuan X., Lim N., Luan J., Ashford S., Wheeler E., Young E.H., Hadley D., Thompson J.R., Braund P.S., Johnson T., Struchalin M., Surakka I., Luben R., Khaw K.T., Rodwell S.A., Loos R.J., Boekholdt S.M., Inouye M., Deloukas P., Elliott P., Schlessinger D., Sanna S., Scuteri A., Jackson A., Mohlke K.L., Tuomilehto J., Roberts R., Stewart A., Kesaniemi Y.A., Mahley R.W., Grundy S.M., C.Wellcome Trust Case Control, McArdle W., Cardon L., Waeber G., Vollenweider P., Chambers J.C., Boehnke M., Abecasis G.R., Salomaa V., Jarvelin M.R., Ruokonen A., Barroso I., Epstein S.E., Hakonarson H.H., Rader D.J., Reilly M.P., Witteman J.C., Hall A.S., Samani N.J., Strachan D.P., Barter P., van Duijn C.M., Kooner J.S., Peltonen L., Wareham N.J., McPherson R., Mooser V., Sandhu M.S. Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler. Thromb. Vasc. Biol. 2010, 30:2264-2276.
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 2264-2276
-
-
Waterworth, D.M.1
Ricketts, S.L.2
Song, K.3
Chen, L.4
Zhao, J.H.5
Ripatti, S.6
Aulchenko, Y.S.7
Zhang, W.8
Yuan, X.9
Lim, N.10
Luan, J.11
Ashford, S.12
Wheeler, E.13
Young, E.H.14
Hadley, D.15
Thompson, J.R.16
Braund, P.S.17
Johnson, T.18
Struchalin, M.19
Surakka, I.20
Luben, R.21
Khaw, K.T.22
Rodwell, S.A.23
Loos, R.J.24
Boekholdt, S.M.25
Inouye, M.26
Deloukas, P.27
Elliott, P.28
Schlessinger, D.29
Sanna, S.30
Scuteri, A.31
Jackson, A.32
Mohlke, K.L.33
Tuomilehto, J.34
Roberts, R.35
Stewart, A.36
Kesaniemi, Y.A.37
Mahley, R.W.38
Grundy, S.M.39
McArdle, W.40
Cardon, L.41
Waeber, G.42
Vollenweider, P.43
Chambers, J.C.44
Boehnke, M.45
Abecasis, G.R.46
Salomaa, V.47
Jarvelin, M.R.48
Ruokonen, A.49
Barroso, I.50
Epstein, S.E.51
Hakonarson, H.H.52
Rader, D.J.53
Reilly, M.P.54
Witteman, J.C.55
Hall, A.S.56
Samani, N.J.57
Strachan, D.P.58
Barter, P.59
van Duijn, C.M.60
Kooner, J.S.61
Peltonen, L.62
Wareham, N.J.63
McPherson, R.64
Mooser, V.65
Sandhu, M.S.66
more..
-
18
-
-
79952256739
-
The architecture of gene regulatory variation across multiple human tissues: the MuTHER study
-
Nica A.C., Parts L., Glass D., Nisbet J., Barrett A., Sekowska M., Travers M., Potter S., Grundberg E., Small K., Hedman A.K., Bataille V., Tzenova Bell J., Surdulescu G., Dimas A.S., Ingle C., Nestle F.O., di Meglio P., Min J.L., Wilk A., Hammond C.J., Hassanali N., Yang T.P., Montgomery S.B., O'Rahilly S., Lindgren C.M., Zondervan K.T., Soranzo N., Barroso I., Durbin R., Ahmadi K., Deloukas P., McCarthy M.I., Dermitzakis E.T., Spector T.D., Mu T.C. The architecture of gene regulatory variation across multiple human tissues: the MuTHER study. PLoS Genet. 2011, 7:e1002003.
-
(2011)
PLoS Genet.
, vol.7
, pp. e1002003
-
-
Nica, A.C.1
Parts, L.2
Glass, D.3
Nisbet, J.4
Barrett, A.5
Sekowska, M.6
Travers, M.7
Potter, S.8
Grundberg, E.9
Small, K.10
Hedman, A.K.11
Bataille, V.12
Tzenova Bell, J.13
Surdulescu, G.14
Dimas, A.S.15
Ingle, C.16
Nestle, F.O.17
di Meglio, P.18
Min, J.L.19
Wilk, A.20
Hammond, C.J.21
Hassanali, N.22
Yang, T.P.23
Montgomery, S.B.24
O'Rahilly, S.25
Lindgren, C.M.26
Zondervan, K.T.27
Soranzo, N.28
Barroso, I.29
Durbin, R.30
Ahmadi, K.31
Deloukas, P.32
McCarthy, M.I.33
Dermitzakis, E.T.34
Spector, T.D.35
Mu, T.C.36
more..
-
19
-
-
79960943621
-
Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability
-
Sanna S., Li B., Mulas A., Sidore C., Kang H.M., Jackson A.U., Piras M.G., Usala G., Maninchedda G., Sassu A., Serra F., Palmas M.A., Wood W.H., Njolstad I., Laakso M., Hveem K., Tuomilehto J., Lakka T.A., Rauramaa R., Boehnke M., Cucca F., Uda M., Schlessinger D., Nagaraja R., Abecasis G.R. Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability. PLoS Genet. 2011, 7:e1002198.
-
(2011)
PLoS Genet.
, vol.7
, pp. e1002198
-
-
Sanna, S.1
Li, B.2
Mulas, A.3
Sidore, C.4
Kang, H.M.5
Jackson, A.U.6
Piras, M.G.7
Usala, G.8
Maninchedda, G.9
Sassu, A.10
Serra, F.11
Palmas, M.A.12
Wood, W.H.13
Njolstad, I.14
Laakso, M.15
Hveem, K.16
Tuomilehto, J.17
Lakka, T.A.18
Rauramaa, R.19
Boehnke, M.20
Cucca, F.21
Uda, M.22
Schlessinger, D.23
Nagaraja, R.24
Abecasis, G.R.25
more..
-
20
-
-
77955499945
-
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
-
Musunuru K., Strong A., Frank-Kamenetsky M., Lee N.E., Ahfeldt T., Sachs K.V., Li X., Li H., Kuperwasser N., Ruda V.M., Pirruccello J.P., Muchmore B., Prokunina-Olsson L., Hall J.L., Schadt E.E., Morales C.R., Lund-Katz S., Phillips M.C., Wong J., Cantley W., Racie T., Ejebe K.G., Orho-Melander M., Melander O., Koteliansky V., Fitzgerald K., Krauss R.M., Cowan C.A., Kathiresan S., Rader D.J. From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature 2010, 466:714-719.
-
(2010)
Nature
, vol.466
, pp. 714-719
-
-
Musunuru, K.1
Strong, A.2
Frank-Kamenetsky, M.3
Lee, N.E.4
Ahfeldt, T.5
Sachs, K.V.6
Li, X.7
Li, H.8
Kuperwasser, N.9
Ruda, V.M.10
Pirruccello, J.P.11
Muchmore, B.12
Prokunina-Olsson, L.13
Hall, J.L.14
Schadt, E.E.15
Morales, C.R.16
Lund-Katz, S.17
Phillips, M.C.18
Wong, J.19
Cantley, W.20
Racie, T.21
Ejebe, K.G.22
Orho-Melander, M.23
Melander, O.24
Koteliansky, V.25
Fitzgerald, K.26
Krauss, R.M.27
Cowan, C.A.28
Kathiresan, S.29
Rader, D.J.30
more..
-
21
-
-
78649237332
-
Fine-mapping in African Americans of 8 recently discovered genetic loci for plasma lipids: the Jackson Heart Study
-
Keebler M.E., Deo R.C., Surti A., Konieczkowski D., Guiducci C., Burtt N., Buxbaum S.G., Sarpong D.F., Steffes M.W., Wilson J.G., Taylor H.A., Kathiresan S. Fine-mapping in African Americans of 8 recently discovered genetic loci for plasma lipids: the Jackson Heart Study. Circ. Cardiovasc. Genet 2010, 3:358-364.
-
(2010)
Circ. Cardiovasc. Genet
, vol.3
, pp. 358-364
-
-
Keebler, M.E.1
Deo, R.C.2
Surti, A.3
Konieczkowski, D.4
Guiducci, C.5
Burtt, N.6
Buxbaum, S.G.7
Sarpong, D.F.8
Steffes, M.W.9
Wilson, J.G.10
Taylor, H.A.11
Kathiresan, S.12
-
22
-
-
0035337657
-
Trans-ethnic fine mapping of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE)
-
McKenzie C.A., Abecasis G.R., Keavney B., Forrester T., Ratcliffe P.J., Julier C., Connell J.M., Bennett F., McFarlane-Anderson N., Lathrop G.M., Cardon L.R. Trans-ethnic fine mapping of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE). Hum. Mol. Genet. 2001, 10:1077-1084.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1077-1084
-
-
McKenzie, C.A.1
Abecasis, G.R.2
Keavney, B.3
Forrester, T.4
Ratcliffe, P.J.5
Julier, C.6
Connell, J.M.7
Bennett, F.8
McFarlane-Anderson, N.9
Lathrop, G.M.10
Cardon, L.R.11
-
23
-
-
59249102911
-
Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study
-
Deo R.C., Reich D., Tandon A., Akylbekova E., Patterson N., Waliszewska A., Kathiresan S., Sarpong D., Taylor H.A., Wilson J.G. Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study. PLoS Genet. 2009, 5:e1000342.
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000342
-
-
Deo, R.C.1
Reich, D.2
Tandon, A.3
Akylbekova, E.4
Patterson, N.5
Waliszewska, A.6
Kathiresan, S.7
Sarpong, D.8
Taylor, H.A.9
Wilson, J.G.10
-
24
-
-
79955550445
-
A user's guide to the encyclopedia of DNA elements (ENCODE)
-
E.P.Consortium A user's guide to the encyclopedia of DNA elements (ENCODE). PLoS Biol. 2011, 9:e1001046.
-
(2011)
PLoS Biol.
, vol.9
, pp. e1001046
-
-
Consortium, E.P.1
-
25
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
E.P.Consortium, Bernstein B.E., Birney E., Dunham I., Green E.D., Gunter C., Snyder M. An integrated encyclopedia of DNA elements in the human genome. Nature 2012, 489:57-74.
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Consortium, E.P.1
Bernstein, B.E.2
Birney, E.3
Dunham, I.4
Green, E.D.5
Gunter, C.6
Snyder, M.7
-
26
-
-
84865739425
-
Architecture of the human regulatory network derived from ENCODE data
-
Gerstein M.B., Kundaje A., Hariharan M., Landt S.G., Yan K.K., Cheng C., Mu X.J., Khurana E., Rozowsky J., Alexander R., Min R., Alves P., Abyzov A., Addleman N., Bhardwaj N., Boyle A.P., Cayting P., Charos A., Chen D.Z., Cheng Y., Clarke D., Eastman C., Euskirchen G., Frietze S., Fu Y., Gertz J., Grubert F., Harmanci A., Jain P., Kasowski M., Lacroute P., Leng J., Lian J., Monahan H., O'Geen H., Ouyang Z., Partridge E.C., Patacsil D., Pauli F., Raha D., Ramirez L., Reddy T.E., Reed B., Shi M., Slifer T., Wang J., Wu L., Yang X., Yip K.Y., Zilberman-Schapira G., Batzoglou S., Sidow A., Farnham P.J., Myers R.M., Weissman S.M., Snyder M. Architecture of the human regulatory network derived from ENCODE data. Nature 2012, 489:91-100.
-
(2012)
Nature
, vol.489
, pp. 91-100
-
-
Gerstein, M.B.1
Kundaje, A.2
Hariharan, M.3
Landt, S.G.4
Yan, K.K.5
Cheng, C.6
Mu, X.J.7
Khurana, E.8
Rozowsky, J.9
Alexander, R.10
Min, R.11
Alves, P.12
Abyzov, A.13
Addleman, N.14
Bhardwaj, N.15
Boyle, A.P.16
Cayting, P.17
Charos, A.18
Chen, D.Z.19
Cheng, Y.20
Clarke, D.21
Eastman, C.22
Euskirchen, G.23
Frietze, S.24
Fu, Y.25
Gertz, J.26
Grubert, F.27
Harmanci, A.28
Jain, P.29
Kasowski, M.30
Lacroute, P.31
Leng, J.32
Lian, J.33
Monahan, H.34
O'Geen, H.35
Ouyang, Z.36
Partridge, E.C.37
Patacsil, D.38
Pauli, F.39
Raha, D.40
Ramirez, L.41
Reddy, T.E.42
Reed, B.43
Shi, M.44
Slifer, T.45
Wang, J.46
Wu, L.47
Yang, X.48
Yip, K.Y.49
Zilberman-Schapira, G.50
Batzoglou, S.51
Sidow, A.52
Farnham, P.J.53
Myers, R.M.54
Weissman, S.M.55
Snyder, M.56
more..
-
27
-
-
84865822182
-
Systematic localization of common disease-associated variation in regulatory DNA
-
Maurano M.T., Humbert R., Rynes E., Thurman R.E., Haugen E., Wang H., Reynolds A.P., Sandstrom R., Qu H., Brody J., Shafer A., Neri F., Lee K., Kutyavin T., Stehling-Sun S., Johnson A.K., Canfield T.K., Giste E., Diegel M., Bates D., Hansen R.S., Neph S., Sabo P.J., Heimfeld S., Raubitschek A., Ziegler S., Cotsapas C., Sotoodehnia N., Glass I., Sunyaev S.R., Kaul R., Stamatoyannopoulos J.A. Systematic localization of common disease-associated variation in regulatory DNA. Science 2012, 337:1190-1195.
-
(2012)
Science
, vol.337
, pp. 1190-1195
-
-
Maurano, M.T.1
Humbert, R.2
Rynes, E.3
Thurman, R.E.4
Haugen, E.5
Wang, H.6
Reynolds, A.P.7
Sandstrom, R.8
Qu, H.9
Brody, J.10
Shafer, A.11
Neri, F.12
Lee, K.13
Kutyavin, T.14
Stehling-Sun, S.15
Johnson, A.K.16
Canfield, T.K.17
Giste, E.18
Diegel, M.19
Bates, D.20
Hansen, R.S.21
Neph, S.22
Sabo, P.J.23
Heimfeld, S.24
Raubitschek, A.25
Ziegler, S.26
Cotsapas, C.27
Sotoodehnia, N.28
Glass, I.29
Sunyaev, S.R.30
Kaul, R.31
Stamatoyannopoulos, J.A.32
more..
-
28
-
-
84889580677
-
Using chromatin marks to interpret and localize genetic associations to complex human traits and diseases
-
Trynka G., Raychaudhuri S. Using chromatin marks to interpret and localize genetic associations to complex human traits and diseases. Curr. Opin. Genet. Dev. 2013, 23:635-641.
-
(2013)
Curr. Opin. Genet. Dev.
, vol.23
, pp. 635-641
-
-
Trynka, G.1
Raychaudhuri, S.2
-
29
-
-
84873086126
-
Chromatin marks identify critical cell types for fine mapping complex trait variants
-
Trynka G., Sandor C., Han B., Xu H., Stranger B.E., Liu X.S., Raychaudhuri S. Chromatin marks identify critical cell types for fine mapping complex trait variants. Nat. Genet. 2013, 45:124-130.
-
(2013)
Nat. Genet.
, vol.45
, pp. 124-130
-
-
Trynka, G.1
Sandor, C.2
Han, B.3
Xu, H.4
Stranger, B.E.5
Liu, X.S.6
Raychaudhuri, S.7
-
30
-
-
84866179291
-
Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arrays
-
Smith A.J., Howard P., Shah S., Eriksson P., Stender S., Giambartolomei C., Folkersen L., Tybjaerg-Hansen A., Kumari M., Palmen J., Hingorani A.D., Talmud P.J., Humphries S.E. Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arrays. PLoS Genet. 2012, 8:e1002908.
-
(2012)
PLoS Genet.
, vol.8
, pp. e1002908
-
-
Smith, A.J.1
Howard, P.2
Shah, S.3
Eriksson, P.4
Stender, S.5
Giambartolomei, C.6
Folkersen, L.7
Tybjaerg-Hansen, A.8
Kumari, M.9
Palmen, J.10
Hingorani, A.D.11
Talmud, P.J.12
Humphries, S.E.13
-
31
-
-
77952497530
-
Allelic expression imbalance at high-density lipoprotein cholesterol locus MMAB-MVK
-
Fogarty M.P., Xiao R., Prokunina-Olsson L., Scott L.J., Mohlke K.L. Allelic expression imbalance at high-density lipoprotein cholesterol locus MMAB-MVK. Hum. Mol. Genet. 2010, 19:1921-1929.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 1921-1929
-
-
Fogarty, M.P.1
Xiao, R.2
Prokunina-Olsson, L.3
Scott, L.J.4
Mohlke, K.L.5
-
32
-
-
77954143522
-
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
-
Voight B.F., Scott L.J., Steinthorsdottir V., Morris A.P., Dina C., Welch R.P., Zeggini E., Huth C., Aulchenko Y.S., Thorleifsson G., McCulloch L.J., Ferreira T., Grallert H., Amin N., Wu G., Willer C.J., Raychaudhuri S., McCarroll S.A., Langenberg C., Hofmann O.M., Dupuis J., Qi L., Segre A.V., van Hoek M., Navarro P., Ardlie K., Balkau B., Benediktsson R., Bennett A.J., Blagieva R., Boerwinkle E., Bonnycastle L.L., Bengtsson Bostrom K., Bravenboer B., Bumpstead S., Burtt N.P., Charpentier G., Chines P.S., Cornelis M., Couper D.J., Crawford G., Doney A.S., Elliott K.S., Elliott A.L., Erdos M.R., Fox C.S., Franklin C.S., Ganser M., Gieger C., Grarup N., Green T., Griffin S., Groves C.J., Guiducci C., Hadjadj S., Hassanali N., Herder C., Isomaa B., Jackson A.U., Johnson P.R., Jorgensen T., Kao W.H., Klopp N., Kong A., Kraft P., Kuusisto J., Lauritzen T., Li M., Lieverse A., Lindgren C.M., Lyssenko V., Marre M., Meitinger T., Midthjell K., Morken M.A., Narisu N., Nilsson P., Owen K.R., Payne F., Perry J.R., Petersen A.K., Platou C., Proenca C., Prokopenko I., Rathmann W., Rayner N.W., Robertson N.R., Rocheleau G., Roden M., Sampson M.J., Saxena R., Shields B.M., Shrader P., Sigurdsson G., Sparso T., Strassburger K., Stringham H.M., Sun Q., Swift A.J., Thorand B., Tichet J., Tuomi T., van Dam R.M., van Haeften T.W., van Herpt T., van Vliet-Ostaptchouk J.V., Walters G.B., Weedon M.N., Wijmenga C., Witteman J., Bergman R.N., Cauchi S., Collins F.S., Gloyn A.L., Gyllensten U., Hansen T., Hide W.A., Hitman G.A., Hofman A., Hunter D.J., Hveem K., Laakso M., Mohlke K.L., Morris A.D., Palmer C.N., Pramstaller P.P., Rudan I., Sijbrands E., Stein L.D., Tuomilehto J., Uitterlinden A., Walker M., Wareham N.J., Watanabe R.M., Abecasis G.R., Boehm B.O., Campbell H., Daly M.J., Hattersley A.T., Hu F.B., Meigs J.B., Pankow J.S., Pedersen O., Wichmann H.E., Barroso I., Florez J.C., Frayling T.M., Groop L., Sladek R., Thorsteinsdottir U., Wilson J.F., Illig T., Froguel P., van Duijn C.M., Stefansson K., Altshuler D., Boehnke M., McCarthy M.I., M.investigators, Consortium G.Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat. Genet. 2010, 42:579-589.
-
(2010)
Nat. Genet.
, vol.42
, pp. 579-589
-
-
Voight, B.F.1
Scott, L.J.2
Steinthorsdottir, V.3
Morris, A.P.4
Dina, C.5
Welch, R.P.6
Zeggini, E.7
Huth, C.8
Aulchenko, Y.S.9
Thorleifsson, G.10
McCulloch, L.J.11
Ferreira, T.12
Grallert, H.13
Amin, N.14
Wu, G.15
Willer, C.J.16
Raychaudhuri, S.17
McCarroll, S.A.18
Langenberg, C.19
Hofmann, O.M.20
Dupuis, J.21
Qi, L.22
Segre, A.V.23
van Hoek, M.24
Navarro, P.25
Ardlie, K.26
Balkau, B.27
Benediktsson, R.28
Bennett, A.J.29
Blagieva, R.30
Boerwinkle, E.31
Bonnycastle, L.L.32
Bengtsson Bostrom, K.33
Bravenboer, B.34
Bumpstead, S.35
Burtt, N.P.36
Charpentier, G.37
Chines, P.S.38
Cornelis, M.39
Couper, D.J.40
Crawford, G.41
Doney, A.S.42
Elliott, K.S.43
Elliott, A.L.44
Erdos, M.R.45
Fox, C.S.46
Franklin, C.S.47
Ganser, M.48
Gieger, C.49
Grarup, N.50
Green, T.51
Griffin, S.52
Groves, C.J.53
Guiducci, C.54
Hadjadj, S.55
Hassanali, N.56
Herder, C.57
Isomaa, B.58
Jackson, A.U.59
Johnson, P.R.60
Jorgensen, T.61
Kao, W.H.62
Klopp, N.63
Kong, A.64
Kraft, P.65
Kuusisto, J.66
Lauritzen, T.67
Li, M.68
Lieverse, A.69
Lindgren, C.M.70
Lyssenko, V.71
Marre, M.72
Meitinger, T.73
Midthjell, K.74
Morken, M.A.75
Narisu, N.76
Nilsson, P.77
Owen, K.R.78
Payne, F.79
Perry, J.R.80
Petersen, A.K.81
Platou, C.82
Proenca, C.83
Prokopenko, I.84
Rathmann, W.85
Rayner, N.W.86
Robertson, N.R.87
Rocheleau, G.88
Roden, M.89
Sampson, M.J.90
Saxena, R.91
Shields, B.M.92
Shrader, P.93
Sigurdsson, G.94
Sparso, T.95
Strassburger, K.96
Stringham, H.M.97
Sun, Q.98
Swift, A.J.99
more..
-
33
-
-
79957607662
-
Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes
-
Small K.S., Hedman A.K., Grundberg E., Nica A.C., Thorleifsson G., Kong A., Thorsteindottir U., Shin S.Y., Richards H.B., G.Consortium, M.Investigators, D.Consortium, Soranzo N., Ahmadi K.R., Lindgren C.M., Stefansson K., Dermitzakis E.T., Deloukas P., Spector T.D., McCarthy M.I., Mu T.C. Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes. Nat. Genet. 2011, 43:561-564.
-
(2011)
Nat. Genet.
, vol.43
, pp. 561-564
-
-
Small, K.S.1
Hedman, A.K.2
Grundberg, E.3
Nica, A.C.4
Thorleifsson, G.5
Kong, A.6
Thorsteindottir, U.7
Shin, S.Y.8
Richards, H.B.9
Soranzo, N.10
Ahmadi, K.R.11
Lindgren, C.M.12
Stefansson, K.13
Dermitzakis, E.T.14
Deloukas, P.15
Spector, T.D.16
McCarthy, M.I.17
Mu, T.C.18
-
34
-
-
84885018609
-
Systematic identification of trans eQTLs as putative drivers of known disease associations
-
Westra H.J., Peters M.J., Esko T., Yaghootkar H., Schurmann C., Kettunen J., Christiansen M.W., Fairfax B.P., Schramm K., Powell J.E., Zhernakova A., Zhernakova D.V., Veldink J.H., Van den Berg L.H., Karjalainen J., Withoff S., Uitterlinden A.G., Hofman A., Rivadeneira F., t Hoen P.A., Reinmaa E., Fischer K., Nelis M., Milani L., Melzer D., Ferrucci L., Singleton A.B., Hernandez D.G., Nalls M.A., Homuth G., Nauck M., Radke D., Volker U., Perola M., Salomaa V., Brody J., Suchy-Dicey A., Gharib S.A., Enquobahrie D.A., Lumley T., Montgomery G.W., Makino S., Prokisch H., Herder C., Roden M., Grallert H., Meitinger T., Strauch K., Li Y., Jansen R.C., Visscher P.M., Knight J.C., Psaty B.M., Ripatti S., Teumer A., Frayling T.M., Metspalu A., van Meurs J.B., Franke L. Systematic identification of trans eQTLs as putative drivers of known disease associations. Nat. Genet. 2013, 45:1238-1243.
-
(2013)
Nat. Genet.
, vol.45
, pp. 1238-1243
-
-
Westra, H.J.1
Peters, M.J.2
Esko, T.3
Yaghootkar, H.4
Schurmann, C.5
Kettunen, J.6
Christiansen, M.W.7
Fairfax, B.P.8
Schramm, K.9
Powell, J.E.10
Zhernakova, A.11
Zhernakova, D.V.12
Veldink, J.H.13
Van den Berg, L.H.14
Karjalainen, J.15
Withoff, S.16
Uitterlinden, A.G.17
Hofman, A.18
Rivadeneira, F.19
t Hoen, P.A.20
Reinmaa, E.21
Fischer, K.22
Nelis, M.23
Milani, L.24
Melzer, D.25
Ferrucci, L.26
Singleton, A.B.27
Hernandez, D.G.28
Nalls, M.A.29
Homuth, G.30
Nauck, M.31
Radke, D.32
Volker, U.33
Perola, M.34
Salomaa, V.35
Brody, J.36
Suchy-Dicey, A.37
Gharib, S.A.38
Enquobahrie, D.A.39
Lumley, T.40
Montgomery, G.W.41
Makino, S.42
Prokisch, H.43
Herder, C.44
Roden, M.45
Grallert, H.46
Meitinger, T.47
Strauch, K.48
Li, Y.49
Jansen, R.C.50
Visscher, P.M.51
Knight, J.C.52
Psaty, B.M.53
Ripatti, S.54
Teumer, A.55
Frayling, T.M.56
Metspalu, A.57
van Meurs, J.B.58
Franke, L.59
more..
-
35
-
-
67649424755
-
Identification of cholesterol-regulating genes by targeted RNAi screening
-
Bartz F., Kern L., Erz D., Zhu M., Gilbert D., Meinhof T., Wirkner U., Erfle H., Muckenthaler M., Pepperkok R., Runz H. Identification of cholesterol-regulating genes by targeted RNAi screening. Cell Metab. 2009, 10:63-75.
-
(2009)
Cell Metab.
, vol.10
, pp. 63-75
-
-
Bartz, F.1
Kern, L.2
Erz, D.3
Zhu, M.4
Gilbert, D.5
Meinhof, T.6
Wirkner, U.7
Erfle, H.8
Muckenthaler, M.9
Pepperkok, R.10
Runz, H.11
-
36
-
-
84874760989
-
RNAi-based functional profiling of loci from blood lipid genome-wide association studies identifies genes with cholesterol-regulatory function
-
Blattmann P., Schuberth C., Pepperkok R., Runz H. RNAi-based functional profiling of loci from blood lipid genome-wide association studies identifies genes with cholesterol-regulatory function. PLoS Genet. 2013, 9:e1003338.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003338
-
-
Blattmann, P.1
Schuberth, C.2
Pepperkok, R.3
Runz, H.4
-
37
-
-
84873733109
-
A TALEN genome-editing system for generating human stem cell-based disease models
-
Ding Q., Lee Y.K., Schaefer E.A., Peters D.T., Veres A., Kim K., Kuperwasser N., Motola D.L., Meissner T.B., Hendriks W.T., Trevisan M., Gupta R.M., Moisan A., Banks E., Friesen M., Schinzel R.T., Xia F., Tang A., Xia Y., Figueroa E., Wann A., Ahfeldt T., Daheron L., Zhang F., Rubin L.L., Peng L.F., Chung R.T., Musunuru K., Cowan C.A. A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell 2013, 12:238-251.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 238-251
-
-
Ding, Q.1
Lee, Y.K.2
Schaefer, E.A.3
Peters, D.T.4
Veres, A.5
Kim, K.6
Kuperwasser, N.7
Motola, D.L.8
Meissner, T.B.9
Hendriks, W.T.10
Trevisan, M.11
Gupta, R.M.12
Moisan, A.13
Banks, E.14
Friesen, M.15
Schinzel, R.T.16
Xia, F.17
Tang, A.18
Xia, Y.19
Figueroa, E.20
Wann, A.21
Ahfeldt, T.22
Daheron, L.23
Zhang, F.24
Rubin, L.L.25
Peng, L.F.26
Chung, R.T.27
Musunuru, K.28
Cowan, C.A.29
more..
-
38
-
-
84875963894
-
Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs
-
Ding Q., Regan S.N., Xia Y., Oostrom L.A., Cowan C.A., Musunuru K. Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs. Cell Stem Cell 2013, 12:393-394.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 393-394
-
-
Ding, Q.1
Regan, S.N.2
Xia, Y.3
Oostrom, L.A.4
Cowan, C.A.5
Musunuru, K.6
-
39
-
-
84908329714
-
Mining the genome for lipid genes
-
(Epub ahead of print, 2014 May 2
-
Kuivenhoven J.A., Hegele R.A. Mining the genome for lipid genes. Biochim. Biophys. Acta 2014, (Epub ahead of print, 2014 May 2, pii: S0925-4439(14)00115-X). 10.1016/j.bbadis.2014.04.028.
-
(2014)
Biochim. Biophys. Acta
-
-
Kuivenhoven, J.A.1
Hegele, R.A.2
-
40
-
-
34547623750
-
Genomewide association analysis of coronary artery disease
-
Samani N.J., Erdmann J., Hall A.S., Hengstenberg C., Mangino M., Mayer B., Dixon R.J., Meitinger T., Braund P., Wichmann H.E., Barrett J.H., Konig I.R., Stevens S.E., Szymczak S., Tregouet D.A., Iles M.M., Pahlke F., Pollard H., Lieb W., Cambien F., Fischer M., Ouwehand W., Blankenberg S., Balmforth A.J., Baessler A., Ball S.G., Strom T.M., Braenne I., Gieger C., Deloukas P., Tobin M.D., Ziegler A., Thompson J.R., Schunkert H., Wtccc, C. The Cardiogenics Genomewide association analysis of coronary artery disease. N. Engl. J. Med. 2007, 357:443-453.
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 443-453
-
-
Samani, N.J.1
Erdmann, J.2
Hall, A.S.3
Hengstenberg, C.4
Mangino, M.5
Mayer, B.6
Dixon, R.J.7
Meitinger, T.8
Braund, P.9
Wichmann, H.E.10
Barrett, J.H.11
Konig, I.R.12
Stevens, S.E.13
Szymczak, S.14
Tregouet, D.A.15
Iles, M.M.16
Pahlke, F.17
Pollard, H.18
Lieb, W.19
Cambien, F.20
Fischer, M.21
Ouwehand, W.22
Blankenberg, S.23
Balmforth, A.J.24
Baessler, A.25
Ball, S.G.26
Strom, T.M.27
Braenne, I.28
Gieger, C.29
Deloukas, P.30
Tobin, M.D.31
Ziegler, A.32
Thompson, J.R.33
Schunkert, H.34
Wtccc, C.35
more..
-
41
-
-
44449090993
-
Presecretory oxidation, aggregation, and autophagic destruction of apoprotein-B: a pathway for late-stage quality control
-
Pan M., Maitin V., Parathath S., Andreo U., Lin S.X., St Germain C., Yao Z., Maxfield F.R., Williams K.J., Fisher E.A. Presecretory oxidation, aggregation, and autophagic destruction of apoprotein-B: a pathway for late-stage quality control. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:5862-5867.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 5862-5867
-
-
Pan, M.1
Maitin, V.2
Parathath, S.3
Andreo, U.4
Lin, S.X.5
St Germain, C.6
Yao, Z.7
Maxfield, F.R.8
Williams, K.J.9
Fisher, E.A.10
-
42
-
-
77956327982
-
Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export
-
Kjolby M., Andersen O.M., Breiderhoff T., Fjorback A.W., Pedersen K.M., Madsen P., Jansen P., Heeren J., Willnow T.E., Nykjaer A. Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export. Cell Metab. 2010, 12:213-223.
-
(2010)
Cell Metab.
, vol.12
, pp. 213-223
-
-
Kjolby, M.1
Andersen, O.M.2
Breiderhoff, T.3
Fjorback, A.W.4
Pedersen, K.M.5
Madsen, P.6
Jansen, P.7
Heeren, J.8
Willnow, T.E.9
Nykjaer, A.10
-
43
-
-
78449286213
-
Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin
-
Hu F., Padukkavidana T., Vaegter C.B., Brady O.A., Zheng Y., Mackenzie I.R., Feldman H.H., Nykjaer A., Strittmatter S.M. Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin. Neuron 2010, 68:654-667.
-
(2010)
Neuron
, vol.68
, pp. 654-667
-
-
Hu, F.1
Padukkavidana, T.2
Vaegter, C.B.3
Brady, O.A.4
Zheng, Y.5
Mackenzie, I.R.6
Feldman, H.H.7
Nykjaer, A.8
Strittmatter, S.M.9
-
44
-
-
35548930820
-
Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury
-
Jansen P., Giehl K., Nyengaard J.R., Teng K., Lioubinski O., Sjoegaard S.S., Breiderhoff T., Gotthardt M., Lin F., Eilers A., Petersen C.M., Lewin G.R., Hempstead B.L., Willnow T.E., Nykjaer A. Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury. Nat. Neurosci. 2007, 10:1449-1457.
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 1449-1457
-
-
Jansen, P.1
Giehl, K.2
Nyengaard, J.R.3
Teng, K.4
Lioubinski, O.5
Sjoegaard, S.S.6
Breiderhoff, T.7
Gotthardt, M.8
Lin, F.9
Eilers, A.10
Petersen, C.M.11
Lewin, G.R.12
Hempstead, B.L.13
Willnow, T.E.14
Nykjaer, A.15
-
45
-
-
70349785144
-
The inactivation of the sortilin gene leads to a partial disruption of prosaposin trafficking to the lysosomes
-
Zeng J., Racicott J., Morales C.R. The inactivation of the sortilin gene leads to a partial disruption of prosaposin trafficking to the lysosomes. Exp. Cell Res. 2009, 315:3112-3124.
-
(2009)
Exp. Cell Res.
, vol.315
, pp. 3112-3124
-
-
Zeng, J.1
Racicott, J.2
Morales, C.R.3
-
46
-
-
84864759987
-
Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism
-
Strong A., Ding Q., Edmondson A.C., Millar J.S., Sachs K.V., Li X., Kumaravel A., Wang M.Y., Ai D., Guo L., Alexander E.T., Nguyen D., Lund-Katz S., Phillips M.C., Morales C.R., Tall A.R., Kathiresan S., Fisher E.A., Musunuru K., Rader D.J. Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism. J. Clin. Invest. 2012, 122:2807-2816.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 2807-2816
-
-
Strong, A.1
Ding, Q.2
Edmondson, A.C.3
Millar, J.S.4
Sachs, K.V.5
Li, X.6
Kumaravel, A.7
Wang, M.Y.8
Ai, D.9
Guo, L.10
Alexander, E.T.11
Nguyen, D.12
Lund-Katz, S.13
Phillips, M.C.14
Morales, C.R.15
Tall, A.R.16
Kathiresan, S.17
Fisher, E.A.18
Musunuru, K.19
Rader, D.J.20
more..
-
47
-
-
84861233637
-
Sortilin as a regulator of lipoprotein metabolism
-
Strong A., Rader D.J. Sortilin as a regulator of lipoprotein metabolism. Curr. Atheroscler. Rep. 2012, 14:211-218.
-
(2012)
Curr. Atheroscler. Rep.
, vol.14
, pp. 211-218
-
-
Strong, A.1
Rader, D.J.2
-
48
-
-
84871969762
-
Large-scale association analysis identifies new risk loci for coronary artery disease
-
C.A.D.Consortium, Deloukas P., Kanoni S., Willenborg C., Farrall M., Assimes T.L., Thompson J.R., Ingelsson E., Saleheen D., Erdmann J., Goldstein B.A., Stirrups K., Konig I.R., Cazier J.B., Johansson A., Hall A.S., Lee J.Y., Willer C.J., Chambers J.C., Esko T., Folkersen L., Goel A., Grundberg E., Havulinna A.S., Ho W.K., Hopewell J.C., Eriksson N., Kleber M.E., Kristiansson K., Lundmark P., Lyytikainen L.P., Rafelt S., Shungin D., Strawbridge R.J., Thorleifsson G., Tikkanen E., Van Zuydam N., Voight B.F., Waite L.L., Zhang W., Ziegler A., Absher D., Altshuler D., Balmforth A.J., Barroso I., Braund P.S., Burgdorf C., Claudi-Boehm S., Cox D., Dimitriou M., Do R., D.Consortium, C.Consortium, Doney A.S., El Mokhtari N., Eriksson P., Fischer K., Fontanillas P., Franco-Cereceda A., Gigante B., Groop L., Gustafsson S., Hager J., Hallmans G., Han B.G., Hunt S.E., Kang H.M., Illig T., Kessler T., Knowles J.W., Kolovou G., Kuusisto J., Langenberg C., Langford C., Leander K., Lokki M.L., Lundmark A., McCarthy M.I., Meisinger C., Melander O., Mihailov E., Maouche S., Morris A.D., Muller-Nurasyid M., Mu T.C., Nikus K., Peden J.F., Rayner N.W., Rasheed A., Rosinger S., Rubin D., Rumpf M.P., Schafer A., Sivananthan M., Song C., Stewart A.F., Tan S.T., Thorgeirsson G., van der Schoot C.E., Wagner P.J., C.Wellcome Trust Case Control, Wells G.A., Wild P.S., Yang T.P., Amouyel P., Arveiler D., Basart H., Boehnke M., Boerwinkle E., Brambilla P., Cambien F., Cupples A.L., de Faire U., Dehghan A., Diemert P., Epstein S.E., Evans A., Ferrario M.M., Ferrieres J., Gauguier D., Go A.S., Goodall A.H., Gudnason V., Hazen S.L., Holm H., Iribarren C., Jang Y., Kahonen M., Kee F., Kim H.S., Klopp N., Koenig W., Kratzer W., Kuulasmaa K., Laakso M., Laaksonen R., Lee J.Y., Lind L., Ouwehand W.H., Parish S., Park J.E., Pedersen N.L., Peters A., Quertermous T., Rader D.J., Salomaa V., Schadt E., Shah S.H., Sinisalo J., Stark K., Stefansson K., Tregouet D.A., Virtamo J., Wallentin L., Wareham N., Zimmermann M.E., Nieminen M.S., Hengstenberg C., Sandhu M.S., Pastinen T., Syvanen A.C., Hovingh G.K., Dedoussis G., Franks P.W., Lehtimaki T., Metspalu A., Zalloua P.A., Siegbahn A., Schreiber S., Ripatti S., Blankenberg S.S., Perola M., Clarke R., Boehm B.O., O'Donnell C., Reilly M.P., Marz W., Collins R., Kathiresan S., Hamsten A., Kooner J.S., Thorsteinsdottir U., Danesh J., Palmer C.N., Roberts R., Watkins H., Schunkert H., Samani N.J. Large-scale association analysis identifies new risk loci for coronary artery disease. Nat. Genet. 2013, 45:25-33.
-
(2013)
Nat. Genet.
, vol.45
, pp. 25-33
-
-
Kanoni, S.1
Farrall, M.2
Thompson, J.R.3
Saleheen, D.4
Goldstein, B.A.5
Konig, I.R.6
Johansson, A.7
Lee, J.Y.8
Chambers, J.C.9
Folkersen, L.10
Grundberg, E.11
Ho, W.K.12
Eriksson, N.13
Kristiansson, K.14
Lyytikainen, L.P.15
Shungin, D.16
Thorleifsson, G.17
Van Zuydam, N.18
Waite, L.L.19
Ziegler, A.20
Altshuler, D.21
Barroso, I.22
Burgdorf, C.23
Cox, D.24
Do, R.25
El Mokhtari, N.26
Fischer, K.27
Franco-Cereceda, A.28
Groop, L.29
Hager, J.30
Han, B.G.31
Kang, H.M.32
Kessler, T.33
Kolovou, G.34
Langenberg, C.35
Leander, K.36
Lundmark, A.37
Meisinger, C.38
Mihailov, E.39
Morris, A.D.40
Mu, T.C.41
Peden, J.F.42
Rasheed, A.43
Rubin, D.44
Schafer, A.45
Song, C.46
Tan, S.T.47
van der Schoot, C.E.48
more..
-
49
-
-
80053452394
-
Large-scale gene-centric analysis identifies novel variants for coronary artery disease
-
I.K.C.Consortium Large-scale gene-centric analysis identifies novel variants for coronary artery disease. PLoS Genet. 2011, 7:e1002260.
-
(2011)
PLoS Genet.
, vol.7
, pp. e1002260
-
-
-
50
-
-
80055024880
-
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma
-
Chambers J.C., Zhang W., Sehmi J., Li X., Wass M.N., Van der Harst P., Holm H., Sanna S., Kavousi M., Baumeister S.E., Coin L.J., Deng G., Gieger C., Heard-Costa N.L., Hottenga J.J., Kuhnel B., Kumar V., Lagou V., Liang L., Luan J., Vidal P.M., Mateo Leach I., O'Reilly P.F., Peden J.F., Rahmioglu N., Soininen P., Speliotes E.K., Yuan X., Thorleifsson G., Alizadeh B.Z., Atwood L.D., Borecki I.B., Brown M.J., Charoen P., Cucca F., Das D., de Geus E.J., Dixon A.L., Doring A., Ehret G., Eyjolfsson G.I., Farrall M., Forouhi N.G., Friedrich N., Goessling W., Gudbjartsson D.F., Harris T.B., Hartikainen A.L., Heath S., Hirschfield G.M., Hofman A., Homuth G., Hypponen E., Janssen H.L., Johnson T., Kangas A.J., Kema I.P., Kuhn J.P., Lai S., Lathrop M., Lerch M.M., Li Y., Liang T.J., Lin J.P., Loos R.J., Martin N.G., Moffatt M.F., Montgomery G.W., Munroe P.B., Musunuru K., Nakamura Y., O'Donnell C.J., Olafsson I., Penninx B.W., Pouta A., Prins B.P., Prokopenko I., Puls R., Ruokonen A., Savolainen M.J., Schlessinger D., Schouten J.N., Seedorf U., Sen-Chowdhry S., Siminovitch K.A., Smit J.H., Spector T.D., Tan W., Teslovich T.M., Tukiainen T., Uitterlinden A.G., Van der Klauw M.M., Vasan R.S., Wallace C., Wallaschofski H., Wichmann H.E., Willemsen G., Wurtz P., Xu C., Yerges-Armstrong L.M., Alcohol Genome-wide Association (AlcGen) Consortium, Diabetes Genetics Replication and Meta-analyses (Diagram +) Study, Genetic Investigation of Anthropometric Traits (GIANT) Consortium, Global Lipids Genetics Consortium, Genetics of Liver Disease (GOLD) Consortium, International Consortium for Blood Pressure (IBCP-GWAS), Meta-analyses of Glucose and Insulin-RelatedTraits Consortium (MAGIC), Abecasis G.R., Ahmadi K.R., Boomsma D.I., Caulfield M., Cookson W.O., van Duijn C.M., Froguel P., Matsuda K., McCarthy M.I., Meisinger C., Mooser V., Pietilainen K.H., Schumann G., Snieder H., Sternberg M.J., Stolk R.P., Thomas H.C., Thorsteinsdottir U., Uda M., Waeber G., Wareham N.J., Waterworth D.M., Watkins H., Whitfield J.B., Witteman J.C., Wolffenbuttel B.H., Fox C.S., Ala-Korpela M., Stefansson K., Vollenweider P., Volzke H., Schadt E.E., Scott J., Jarvelin M.R., Elliott P., Kooner J.S. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat. Genet. 2011, 43:1131-1138.
-
(2011)
Nat. Genet.
, vol.43
, pp. 1131-1138
-
-
Chambers, J.C.1
Zhang, W.2
Sehmi, J.3
Li, X.4
Wass, M.N.5
Van der Harst, P.6
Holm, H.7
Sanna, S.8
Kavousi, M.9
Baumeister, S.E.10
Coin, L.J.11
Deng, G.12
Gieger, C.13
Heard-Costa, N.L.14
Hottenga, J.J.15
Kuhnel, B.16
Kumar, V.17
Lagou, V.18
Liang, L.19
Luan, J.20
Vidal, P.M.21
Mateo Leach, I.22
O'Reilly, P.F.23
Peden, J.F.24
Rahmioglu, N.25
Soininen, P.26
Speliotes, E.K.27
Yuan, X.28
Thorleifsson, G.29
Alizadeh, B.Z.30
Atwood, L.D.31
Borecki, I.B.32
Brown, M.J.33
Charoen, P.34
Cucca, F.35
Das, D.36
de Geus, E.J.37
Dixon, A.L.38
Doring, A.39
Ehret, G.40
Eyjolfsson, G.I.41
Farrall, M.42
Forouhi, N.G.43
Friedrich, N.44
Goessling, W.45
Gudbjartsson, D.F.46
Harris, T.B.47
Hartikainen, A.L.48
Heath, S.49
Hirschfield, G.M.50
Hofman, A.51
Homuth, G.52
Hypponen, E.53
Janssen, H.L.54
Johnson, T.55
Kangas, A.J.56
Kema, I.P.57
Kuhn, J.P.58
Lai, S.59
Lathrop, M.60
Lerch, M.M.61
Li, Y.62
Liang, T.J.63
Lin, J.P.64
Loos, R.J.65
Martin, N.G.66
Moffatt, M.F.67
Montgomery, G.W.68
Munroe, P.B.69
Musunuru, K.70
Nakamura, Y.71
O'Donnell, C.J.72
Olafsson, I.73
Penninx, B.W.74
Pouta, A.75
Prins, B.P.76
Prokopenko, I.77
Puls, R.78
Ruokonen, A.79
Savolainen, M.J.80
Schlessinger, D.81
Schouten, J.N.82
Seedorf, U.83
Sen-Chowdhry, S.84
Siminovitch, K.A.85
Smit, J.H.86
Spector, T.D.87
Tan, W.88
Teslovich, T.M.89
Tukiainen, T.90
Uitterlinden, A.G.91
Van der Klauw, M.M.92
Vasan, R.S.93
Wallace, C.94
Wallaschofski, H.95
Wichmann, H.E.96
Willemsen, G.97
Wurtz, P.98
Xu, C.99
more..
-
51
-
-
84859238629
-
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals
-
Dastani Z., Hivert M.F., Timpson N., Perry J.R., Yuan X., Scott R.A., Henneman P., Heid I.M., Kizer J.R., Lyytikainen L.P., Fuchsberger C., Tanaka T., Morris A.P., Small K., Isaacs A., Beekman M., Coassin S., Lohman K., Qi L., Kanoni S., Pankow J.S., Uh H.W., Wu Y., Bidulescu A., Rasmussen-Torvik L.J., Greenwood C.M., Ladouceur M., Grimsby J., Manning A.K., Liu C.T., Kooner J., Mooser V.E., Vollenweider P., Kapur K.A., Chambers J., Wareham N.J., Langenberg C., Frants R., Willems-Vandijk K., Oostra B.A., Willems S.M., Lamina C., Winkler T.W., Psaty B.M., Tracy R.P., Brody J., Chen I., Viikari J., Kahonen M., Pramstaller P.P., Evans D.M., St Pourcain B., Sattar N., Wood A.R., Bandinelli S., Carlson O.D., Egan J.M., Bohringer S., van Heemst D., Kedenko L., Kristiansson K., Nuotio M.L., Loo B.M., Harris T., Garcia M., Kanaya A., Haun M., Klopp N., Wichmann H.E., Deloukas P., Katsareli E., Couper D.J., Duncan B.B., Kloppenburg M., et al., Kathiresan S. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 2012, 8:e1002607.
-
(2012)
PLoS Genet.
, vol.8
, pp. e1002607
-
-
Dastani, Z.1
Hivert, M.F.2
Timpson, N.3
Perry, J.R.4
Yuan, X.5
Scott, R.A.6
Henneman, P.7
Heid, I.M.8
Kizer, J.R.9
Lyytikainen, L.P.10
Fuchsberger, C.11
Tanaka, T.12
Morris, A.P.13
Small, K.14
Isaacs, A.15
Beekman, M.16
Coassin, S.17
Lohman, K.18
Qi, L.19
Kanoni, S.20
Pankow, J.S.21
Uh, H.W.22
Wu, Y.23
Bidulescu, A.24
Rasmussen-Torvik, L.J.25
Greenwood, C.M.26
Ladouceur, M.27
Grimsby, J.28
Manning, A.K.29
Liu, C.T.30
Kooner, J.31
Mooser, V.E.32
Vollenweider, P.33
Kapur, K.A.34
Chambers, J.35
Wareham, N.J.36
Langenberg, C.37
Frants, R.38
Willems-Vandijk, K.39
Oostra, B.A.40
Willems, S.M.41
Lamina, C.42
Winkler, T.W.43
Psaty, B.M.44
Tracy, R.P.45
Brody, J.46
Chen, I.47
Viikari, J.48
Kahonen, M.49
Pramstaller, P.P.50
Evans, D.M.51
St Pourcain, B.52
Sattar, N.53
Wood, A.R.54
Bandinelli, S.55
Carlson, O.D.56
Egan, J.M.57
Bohringer, S.58
van Heemst, D.59
Kedenko, L.60
Kristiansson, K.61
Nuotio, M.L.62
Loo, B.M.63
Harris, T.64
Garcia, M.65
Kanaya, A.66
Haun, M.67
Klopp, N.68
Wichmann, H.E.69
Deloukas, P.70
Katsareli, E.71
Couper, D.J.72
Duncan, B.B.73
Kloppenburg, M.74
more..
-
52
-
-
78649874589
-
Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice
-
Burkhardt R., Toh S.A., Lagor W.R., Birkeland A., Levin M., Li X., Robblee M., Fedorov V.D., Yamamoto M., Satoh T., Akira S., Kathiresan S., Breslow J.L., Rader D.J. Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice. J. Clin. Invest. 2010, 120:4410-4414.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 4410-4414
-
-
Burkhardt, R.1
Toh, S.A.2
Lagor, W.R.3
Birkeland, A.4
Levin, M.5
Li, X.6
Robblee, M.7
Fedorov, V.D.8
Yamamoto, M.9
Satoh, T.10
Akira, S.11
Kathiresan, S.12
Breslow, J.L.13
Rader, D.J.14
-
53
-
-
84858788031
-
The tribbles gene family and lipoprotein metabolism
-
Angyal A., Kiss-Toth E. The tribbles gene family and lipoprotein metabolism. Curr. Opin. Lipidol. 2012, 23:122-126.
-
(2012)
Curr. Opin. Lipidol.
, vol.23
, pp. 122-126
-
-
Angyal, A.1
Kiss-Toth, E.2
-
54
-
-
79953732508
-
Functional validation of new pathways in lipoprotein metabolism identified by human genetics
-
Bauer R.C., Stylianou I.M., Rader D.J. Functional validation of new pathways in lipoprotein metabolism identified by human genetics. Curr. Opin. Lipidol. 2011, 22:123-128.
-
(2011)
Curr. Opin. Lipidol.
, vol.22
, pp. 123-128
-
-
Bauer, R.C.1
Stylianou, I.M.2
Rader, D.J.3
-
55
-
-
84875611758
-
Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages
-
Satoh T., Kidoya H., Naito H., Yamamoto M., Takemura N., Nakagawa K., Yoshioka Y., Morii E., Takakura N., Takeuchi O., Akira S. Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages. Nature 2013, 495:524-528.
-
(2013)
Nature
, vol.495
, pp. 524-528
-
-
Satoh, T.1
Kidoya, H.2
Naito, H.3
Yamamoto, M.4
Takemura, N.5
Nakagawa, K.6
Yoshioka, Y.7
Morii, E.8
Takakura, N.9
Takeuchi, O.10
Akira, S.11
-
56
-
-
70349983266
-
A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia
-
Hegele R.A., Ban M.R., Hsueh N., Kennedy B.A., Cao H., Zou G.Y., Anand S., Yusuf S., Huff M.W., Wang J. A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia. Hum. Mol. Genet. 2009, 18:4189-4194.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 4189-4194
-
-
Hegele, R.A.1
Ban, M.R.2
Hsueh, N.3
Kennedy, B.A.4
Cao, H.5
Zou, G.Y.6
Anand, S.7
Yusuf, S.8
Huff, M.W.9
Wang, J.10
-
57
-
-
84873488838
-
Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network
-
Pendergrass S.A., Brown-Gentry K., Dudek S., Frase A., Torstenson E.S., Goodloe R., Ambite J.L., Avery C.L., Buyske S., Buzkova P., Deelman E., Fesinmeyer M.D., Haiman C.A., Heiss G., Hindorff L.A., Hsu C.N., Jackson R.D., Kooperberg C., Le Marchand L., Lin Y., Matise T.C., Monroe K.R., Moreland L., Park S.L., Reiner A., Wallace R., Wilkens L.R., Crawford D.C., Ritchie M.D. Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network. PLoS Genet. 2013, 9:e1003087.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003087
-
-
Pendergrass, S.A.1
Brown-Gentry, K.2
Dudek, S.3
Frase, A.4
Torstenson, E.S.5
Goodloe, R.6
Ambite, J.L.7
Avery, C.L.8
Buyske, S.9
Buzkova, P.10
Deelman, E.11
Fesinmeyer, M.D.12
Haiman, C.A.13
Heiss, G.14
Hindorff, L.A.15
Hsu, C.N.16
Jackson, R.D.17
Kooperberg, C.18
Le Marchand, L.19
Lin, Y.20
Matise, T.C.21
Monroe, K.R.22
Moreland, L.23
Park, S.L.24
Reiner, A.25
Wallace, R.26
Wilkens, L.R.27
Crawford, D.C.28
Ritchie, M.D.29
more..
-
58
-
-
78649246183
-
Association of genetic risk variants with expression of proximal genes identifies novel susceptibility genes for cardiovascular disease
-
Folkersen L., van't Hooft F., Chernogubova E., Agardh H.E., Hansson G.K., Hedin U., Liska J., Syvanen A.C., Paulsson-Berne G., Franco-Cereceda A., Hamsten A., Gabrielsen A., Eriksson P., BiKe, A.s groups Association of genetic risk variants with expression of proximal genes identifies novel susceptibility genes for cardiovascular disease. Circ. Cardiovasc. Genet 2010, 3:365-373.
-
(2010)
Circ. Cardiovasc. Genet
, vol.3
, pp. 365-373
-
-
Folkersen, L.1
van't Hooft, F.2
Chernogubova, E.3
Agardh, H.E.4
Hansson, G.K.5
Hedin, U.6
Liska, J.7
Syvanen, A.C.8
Paulsson-Berne, G.9
Franco-Cereceda, A.10
Hamsten, A.11
Gabrielsen, A.12
Eriksson, P.13
-
59
-
-
82955239839
-
Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man
-
Holleboom A.G., Karlsson H., Lin R.S., Beres T.M., Sierts J.A., Herman D.S., Stroes E.S., Aerts J.M., Kastelein J.J., Motazacker M.M., Dallinga-Thie G.M., Levels J.H., Zwinderman A.H., Seidman J.G., Seidman C.E., Ljunggren S., Lefeber D.J., Morava E., Wevers R.A., Fritz T.A., Tabak L.A., Lindahl M., Hovingh G.K., Kuivenhoven J.A. Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man. Cell Metab. 2011, 14:811-818.
-
(2011)
Cell Metab.
, vol.14
, pp. 811-818
-
-
Holleboom, A.G.1
Karlsson, H.2
Lin, R.S.3
Beres, T.M.4
Sierts, J.A.5
Herman, D.S.6
Stroes, E.S.7
Aerts, J.M.8
Kastelein, J.J.9
Motazacker, M.M.10
Dallinga-Thie, G.M.11
Levels, J.H.12
Zwinderman, A.H.13
Seidman, J.G.14
Seidman, C.E.15
Ljunggren, S.16
Lefeber, D.J.17
Morava, E.18
Wevers, R.A.19
Fritz, T.A.20
Tabak, L.A.21
Lindahl, M.22
Hovingh, G.K.23
Kuivenhoven, J.A.24
more..
-
60
-
-
84862563760
-
Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells
-
Schjoldager K.T., Vakhrushev S.Y., Kong Y., Steentoft C., Nudelman A.S., Pedersen N.B., Wandall H.H., Mandel U., Bennett E.P., Levery S.B., Clausen H. Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:9893-9898.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 9893-9898
-
-
Schjoldager, K.T.1
Vakhrushev, S.Y.2
Kong, Y.3
Steentoft, C.4
Nudelman, A.S.5
Pedersen, N.B.6
Wandall, H.H.7
Mandel, U.8
Bennett, E.P.9
Levery, S.B.10
Clausen, H.11
-
61
-
-
78449258533
-
O-glycosylation modulates proprotein convertase activation of angiopoietin-like protein 3: possible role of polypeptide GalNAc-transferase-2 in regulation of concentrations of plasma lipids
-
Schjoldager K.T., Vester-Christensen M.B., Bennett E.P., Levery S.B., Schwientek T., Yin W., Blixt O., Clausen H. O-glycosylation modulates proprotein convertase activation of angiopoietin-like protein 3: possible role of polypeptide GalNAc-transferase-2 in regulation of concentrations of plasma lipids. J. Biol. Chem. 2010, 285:36293-36303.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 36293-36303
-
-
Schjoldager, K.T.1
Vester-Christensen, M.B.2
Bennett, E.P.3
Levery, S.B.4
Schwientek, T.5
Yin, W.6
Blixt, O.7
Clausen, H.8
-
62
-
-
58149161560
-
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
-
Aulchenko Y.S., Ripatti S., Lindqvist I., Boomsma D., Heid I.M., Pramstaller P.P., Penninx B.W., Janssens A.C., Wilson J.F., Spector T., Martin N.G., Pedersen N.L., Kyvik K.O., Kaprio J., Hofman A., Freimer N.B., Jarvelin M.R., Gyllensten U., Campbell H., Rudan I., Johansson A., Marroni F., Hayward C., Vitart V., Jonasson I., Pattaro C., Wright A., Hastie N., Pichler I., Hicks A.A., Falchi M., Willemsen G., Hottenga J.J., de Geus E.J., Montgomery G.W., Whitfield J., Magnusson P., Saharinen J., Perola M., Silander K., Isaacs A., Sijbrands E.J., Uitterlinden A.G., Witteman J.C., Oostra B.A., Elliott P., Ruokonen A., Sabatti C., Gieger C., Meitinger T., Kronenberg F., Doring A., Wichmann H.E., Smit J.H., McCarthy M.I., van Duijn C.M., Peltonen L., E.Consortium Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat. Genet. 2009, 41:47-55.
-
(2009)
Nat. Genet.
, vol.41
, pp. 47-55
-
-
Aulchenko, Y.S.1
Ripatti, S.2
Lindqvist, I.3
Boomsma, D.4
Heid, I.M.5
Pramstaller, P.P.6
Penninx, B.W.7
Janssens, A.C.8
Wilson, J.F.9
Spector, T.10
Martin, N.G.11
Pedersen, N.L.12
Kyvik, K.O.13
Kaprio, J.14
Hofman, A.15
Freimer, N.B.16
Jarvelin, M.R.17
Gyllensten, U.18
Campbell, H.19
Rudan, I.20
Johansson, A.21
Marroni, F.22
Hayward, C.23
Vitart, V.24
Jonasson, I.25
Pattaro, C.26
Wright, A.27
Hastie, N.28
Pichler, I.29
Hicks, A.A.30
Falchi, M.31
Willemsen, G.32
Hottenga, J.J.33
de Geus, E.J.34
Montgomery, G.W.35
Whitfield, J.36
Magnusson, P.37
Saharinen, J.38
Perola, M.39
Silander, K.40
Isaacs, A.41
Sijbrands, E.J.42
Uitterlinden, A.G.43
Witteman, J.C.44
Oostra, B.A.45
Elliott, P.46
Ruokonen, A.47
Sabatti, C.48
Gieger, C.49
Meitinger, T.50
Kronenberg, F.51
Doring, A.52
Wichmann, H.E.53
Smit, J.H.54
McCarthy, M.I.55
van Duijn, C.M.56
Peltonen, L.57
more..
-
63
-
-
57149114180
-
Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions
-
Heid I.M., Boes E., Muller M., Kollerits B., Lamina C., Coassin S., Gieger C., Doring A., Klopp N., Frikke-Schmidt R., Tybjaerg-Hansen A., Brandstatter A., Luchner A., Meitinger T., Wichmann H.E., Kronenberg F. Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions. Circ. Cardiovasc. Genet 2008, 1:10-20.
-
(2008)
Circ. Cardiovasc. Genet
, vol.1
, pp. 10-20
-
-
Heid, I.M.1
Boes, E.2
Muller, M.3
Kollerits, B.4
Lamina, C.5
Coassin, S.6
Gieger, C.7
Doring, A.8
Klopp, N.9
Frikke-Schmidt, R.10
Tybjaerg-Hansen, A.11
Brandstatter, A.12
Luchner, A.13
Meitinger, T.14
Wichmann, H.E.15
Kronenberg, F.16
-
64
-
-
73649103089
-
Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis
-
Chasman D.I., Pare G., Mora S., Hopewell J.C., Peloso G., Clarke R., Cupples L.A., Hamsten A., Kathiresan S., Malarstig A., Ordovas J.M., Ripatti S., Parker A.N., Miletich J.P., Ridker P.M. Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis. PLoS Genet. 2009, 5:e1000730.
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000730
-
-
Chasman, D.I.1
Pare, G.2
Mora, S.3
Hopewell, J.C.4
Peloso, G.5
Clarke, R.6
Cupples, L.A.7
Hamsten, A.8
Kathiresan, S.9
Malarstig, A.10
Ordovas, J.M.11
Ripatti, S.12
Parker, A.N.13
Miletich, J.P.14
Ridker, P.M.15
-
65
-
-
84855290539
-
Mining the LIPG allelic spectrum reveals the contribution of rare and common regulatory variants to HDL cholesterol
-
Khetarpal S.A., Edmondson A.C., Raghavan A., Neeli H., Jin W., Badellino K.O., Demissie S., Manning A.K., DerOhannessian S.L., Wolfe M.L., Cupples L.A., Li M., Kathiresan S., Rader D.J. Mining the LIPG allelic spectrum reveals the contribution of rare and common regulatory variants to HDL cholesterol. PLoS Genet. 2011, 7:e1002393.
-
(2011)
PLoS Genet.
, vol.7
, pp. e1002393
-
-
Khetarpal, S.A.1
Edmondson, A.C.2
Raghavan, A.3
Neeli, H.4
Jin, W.5
Badellino, K.O.6
Demissie, S.7
Manning, A.K.8
DerOhannessian, S.L.9
Wolfe, M.L.10
Cupples, L.A.11
Li, M.12
Kathiresan, S.13
Rader, D.J.14
-
66
-
-
0033553565
-
Cloning of a unique lipase from endothelial cells extends the lipase gene family
-
Hirata K., Dichek H.L., Cioffi J.A., Choi S.Y., Leeper N.J., Quintana L., Kronmal G.S., Cooper A.D., Quertermous T. Cloning of a unique lipase from endothelial cells extends the lipase gene family. J. Biol. Chem. 1999, 274:14170-14175.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 14170-14175
-
-
Hirata, K.1
Dichek, H.L.2
Cioffi, J.A.3
Choi, S.Y.4
Leeper, N.J.5
Quintana, L.6
Kronmal, G.S.7
Cooper, A.D.8
Quertermous, T.9
-
67
-
-
0032901331
-
A novel endothelial-derived lipase that modulates HDL metabolism
-
Jaye M., Lynch K.J., Krawiec J., Marchadier D., Maugeais C., Doan K., South V., Amin D., Perrone M., Rader D.J. A novel endothelial-derived lipase that modulates HDL metabolism. Nat. Genet. 1999, 21:424-428.
-
(1999)
Nat. Genet.
, vol.21
, pp. 424-428
-
-
Jaye, M.1
Lynch, K.J.2
Krawiec, J.3
Marchadier, D.4
Maugeais, C.5
Doan, K.6
South, V.7
Amin, D.8
Perrone, M.9
Rader, D.J.10
-
68
-
-
0037314398
-
Endothelial lipase is a major determinant of HDL level
-
Ishida T., Choi S., Kundu R.K., Hirata K., Rubin E.M., Cooper A.D., Quertermous T. Endothelial lipase is a major determinant of HDL level. J. Clin. Invest. 2003, 111:347-355.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 347-355
-
-
Ishida, T.1
Choi, S.2
Kundu, R.K.3
Hirata, K.4
Rubin, E.M.5
Cooper, A.D.6
Quertermous, T.7
-
69
-
-
0242286640
-
Dose-dependent acceleration of high-density lipoprotein catabolism by endothelial lipase
-
Maugeais C., Tietge U.J., Broedl U.C., Marchadier D., Cain W., McCoy M.G., Lund-Katz S., Glick J.M., Rader D.J. Dose-dependent acceleration of high-density lipoprotein catabolism by endothelial lipase. Circulation 2003, 108:2121-2126.
-
(2003)
Circulation
, vol.108
, pp. 2121-2126
-
-
Maugeais, C.1
Tietge, U.J.2
Broedl, U.C.3
Marchadier, D.4
Cain, W.5
McCoy, M.G.6
Lund-Katz, S.7
Glick, J.M.8
Rader, D.J.9
-
70
-
-
0037316555
-
Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivo
-
Jin W., Millar J.S., Broedl U., Glick J.M., Rader D.J. Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivo. J. Clin. Invest. 2003, 111:357-362.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 357-362
-
-
Jin, W.1
Millar, J.S.2
Broedl, U.3
Glick, J.M.4
Rader, D.J.5
-
71
-
-
65249186429
-
Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans
-
Edmondson A.C., Brown R.J., Kathiresan S., Cupples L.A., Demissie S., Manning A.K., Jensen M.K., Rimm E.B., Wang J., Rodrigues A., Bamba V., Khetarpal S.A., Wolfe M.L., Derohannessian S., Li M., Reilly M.P., Aberle J., Evans D., Hegele R.A., Rader D.J. Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans. J. Clin. Invest. 2009, 119:1042-1050.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1042-1050
-
-
Edmondson, A.C.1
Brown, R.J.2
Kathiresan, S.3
Cupples, L.A.4
Demissie, S.5
Manning, A.K.6
Jensen, M.K.7
Rimm, E.B.8
Wang, J.9
Rodrigues, A.10
Bamba, V.11
Khetarpal, S.A.12
Wolfe, M.L.13
Derohannessian, S.14
Li, M.15
Reilly, M.P.16
Aberle, J.17
Evans, D.18
Hegele, R.A.19
Rader, D.J.20
more..
-
72
-
-
78650054879
-
Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease
-
Peloso G.M., Demissie S., Collins D., Mirel D.B., Gabriel S.B., Cupples L.A., Robins S.J., Schaefer E.J., Brousseau M.E. Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease. J. Lipid Res. 2010, 51:3524-3532.
-
(2010)
J. Lipid Res.
, vol.51
, pp. 3524-3532
-
-
Peloso, G.M.1
Demissie, S.2
Collins, D.3
Mirel, D.B.4
Gabriel, S.B.5
Cupples, L.A.6
Robins, S.J.7
Schaefer, E.J.8
Brousseau, M.E.9
-
73
-
-
84864845456
-
Plasma HDL cholesterol and risk of myocardial infarction: a Mendelian randomisation study
-
Voight B.F., Peloso G.M., Orho-Melander M., Frikke-Schmidt R., Barbalic M., Jensen M.K., Hindy G., Holm H., Ding E.L., Johnson T., Schunkert H., Samani N.J., Clarke R., Hopewell J.C., Thompson J.F., Li M., Thorleifsson G., Newton-Cheh C., Musunuru K., Pirruccello J.P., Saleheen D., Chen L., Stewart A., Schillert A., Thorsteinsdottir U., Thorgeirsson G., Anand S., Engert J.C., Morgan T., Spertus J., Stoll M., Berger K., Martinelli N., Girelli D., McKeown P.P., Patterson C.C., Epstein S.E., Devaney J., Burnett M.S., Mooser V., Ripatti S., Surakka I., Nieminen M.S., Sinisalo J., Lokki M.L., Perola M., Havulinna A., de Faire U., Gigante B., Ingelsson E., Zeller T., Wild P., de Bakker P.I., Klungel O.H., Maitland-van der Zee A.H., Peters B.J., de Boer A., Grobbee D.E., Kamphuisen P.W., Deneer V.H., Elbers C.C., Onland-Moret N.C., Hofker M.H., Wijmenga C., Verschuren W.M., Boer J.M., van der Schouw Y.T., Rasheed A., Frossard P., Demissie S., Willer C., Do R., Ordovas J.M., Abecasis G.R., Boehnke M., Mohlke K.L., Daly M.J., Guiducci C., Burtt N.P., Surti A., Gonzalez E., Purcell S., Gabriel S., Marrugat J., Peden J., Erdmann J., Diemert P., Willenborg C., Konig I.R., Fischer M., Hengstenberg C., Ziegler A., Buysschaert I., Lambrechts D., Van de Werf F., Fox K.A., El Mokhtari N.E., Rubin D., Schrezenmeir J., Schreiber S., Schafer A., Danesh J., Blankenberg S., Roberts R., McPherson R., Watkins H., Hall A.S., Overvad K., Rimm E., Boerwinkle E., Tybjaerg-Hansen A., Cupples L.A., Reilly M.P., Melander O., Mannucci P.M., Ardissino D., Siscovick D., Elosua R., Stefansson K., O'Donnell C.J., Salomaa V., Rader D.J., Peltonen L., Schwartz S.M., Altshuler D., Kathiresan S. Plasma HDL cholesterol and risk of myocardial infarction: a Mendelian randomisation study. Lancet 2012, 380:572-580.
-
(2012)
Lancet
, vol.380
, pp. 572-580
-
-
Voight, B.F.1
Peloso, G.M.2
Orho-Melander, M.3
Frikke-Schmidt, R.4
Barbalic, M.5
Jensen, M.K.6
Hindy, G.7
Holm, H.8
Ding, E.L.9
Johnson, T.10
Schunkert, H.11
Samani, N.J.12
Clarke, R.13
Hopewell, J.C.14
Thompson, J.F.15
Li, M.16
Thorleifsson, G.17
Newton-Cheh, C.18
Musunuru, K.19
Pirruccello, J.P.20
Saleheen, D.21
Chen, L.22
Stewart, A.23
Schillert, A.24
Thorsteinsdottir, U.25
Thorgeirsson, G.26
Anand, S.27
Engert, J.C.28
Morgan, T.29
Spertus, J.30
Stoll, M.31
Berger, K.32
Martinelli, N.33
Girelli, D.34
McKeown, P.P.35
Patterson, C.C.36
Epstein, S.E.37
Devaney, J.38
Burnett, M.S.39
Mooser, V.40
Ripatti, S.41
Surakka, I.42
Nieminen, M.S.43
Sinisalo, J.44
Lokki, M.L.45
Perola, M.46
Havulinna, A.47
de Faire, U.48
Gigante, B.49
Ingelsson, E.50
Zeller, T.51
Wild, P.52
de Bakker, P.I.53
Klungel, O.H.54
Maitland-van der Zee, A.H.55
Peters, B.J.56
de Boer, A.57
Grobbee, D.E.58
Kamphuisen, P.W.59
Deneer, V.H.60
Elbers, C.C.61
Onland-Moret, N.C.62
Hofker, M.H.63
Wijmenga, C.64
Verschuren, W.M.65
Boer, J.M.66
van der Schouw, Y.T.67
Rasheed, A.68
Frossard, P.69
Demissie, S.70
Willer, C.71
Do, R.72
Ordovas, J.M.73
Abecasis, G.R.74
Boehnke, M.75
Mohlke, K.L.76
Daly, M.J.77
Guiducci, C.78
Burtt, N.P.79
Surti, A.80
Gonzalez, E.81
Purcell, S.82
Gabriel, S.83
Marrugat, J.84
Peden, J.85
Erdmann, J.86
Diemert, P.87
Willenborg, C.88
Konig, I.R.89
Fischer, M.90
Hengstenberg, C.91
Ziegler, A.92
Buysschaert, I.93
Lambrechts, D.94
Van de Werf, F.95
Fox, K.A.96
El Mokhtari, N.E.97
Rubin, D.98
Schrezenmeir, J.99
more..
-
74
-
-
84865693681
-
The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits
-
Voight B.F., Kang H.M., Ding J., Palmer C.D., Sidore C., Chines P.S., Burtt N.P., Fuchsberger C., Li Y., Erdmann J., Frayling T.M., Heid I.M., Jackson A.U., Johnson T., Kilpelainen T.O., Lindgren C.M., Morris A.P., Prokopenko I., Randall J.C., Saxena R., Soranzo N., Speliotes E.K., Teslovich T.M., Wheeler E., Maguire J., Parkin M., Potter S., Rayner N.W., Robertson N., Stirrups K., Winckler W., Sanna S., Mulas A., Nagaraja R., Cucca F., Barroso I., Deloukas P., Loos R.J., Kathiresan S., Munroe P.B., Newton-Cheh C., Pfeufer A., Samani N.J., Schunkert H., Hirschhorn J.N., Altshuler D., McCarthy M.I., Abecasis G.R., Boehnke M. The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. PLoS Genet. 2012, 8:e1002793.
-
(2012)
PLoS Genet.
, vol.8
, pp. e1002793
-
-
Voight, B.F.1
Kang, H.M.2
Ding, J.3
Palmer, C.D.4
Sidore, C.5
Chines, P.S.6
Burtt, N.P.7
Fuchsberger, C.8
Li, Y.9
Erdmann, J.10
Frayling, T.M.11
Heid, I.M.12
Jackson, A.U.13
Johnson, T.14
Kilpelainen, T.O.15
Lindgren, C.M.16
Morris, A.P.17
Prokopenko, I.18
Randall, J.C.19
Saxena, R.20
Soranzo, N.21
Speliotes, E.K.22
Teslovich, T.M.23
Wheeler, E.24
Maguire, J.25
Parkin, M.26
Potter, S.27
Rayner, N.W.28
Robertson, N.29
Stirrups, K.30
Winckler, W.31
Sanna, S.32
Mulas, A.33
Nagaraja, R.34
Cucca, F.35
Barroso, I.36
Deloukas, P.37
Loos, R.J.38
Kathiresan, S.39
Munroe, P.B.40
Newton-Cheh, C.41
Pfeufer, A.42
Samani, N.J.43
Schunkert, H.44
Hirschhorn, J.N.45
Altshuler, D.46
McCarthy, M.I.47
Abecasis, G.R.48
Boehnke, M.49
more..
-
75
-
-
84885194862
-
Fine Mapping and Identification of BMI Loci in African Americans
-
Gong J., Schumacher F., Lim U., Hindorff L.A., Haessler J., Buyske S., Carlson C.S., Rosse S., Buzkova P., Fornage M., Gross M., Pankratz N., Pankow J.S., Schreiner P.J., Cooper R., Ehret G., Gu C.C., Houston D., Irvin M.R., Jackson R., Kuller L., Henderson B., Cheng I., Wilkens L., Leppert M., Lewis C.E., Li R., Nguyen K.D., Goodloe R., Farber-Eger E., Boston J., Dilks H.H., Ritchie M.D., Fowke J., Pooler L., Graff M., Fernandez-Rhodes L., Cochrane B., Boerwinkle E., Kooperberg C., Matise T.C., Le Marchand L., Crawford D.C., Haiman C.A., North K.E., Peters U. Fine Mapping and Identification of BMI Loci in African Americans. Am. J. Hum. Genet. 2013, 93:661-671.
-
(2013)
Am. J. Hum. Genet.
, vol.93
, pp. 661-671
-
-
Gong, J.1
Schumacher, F.2
Lim, U.3
Hindorff, L.A.4
Haessler, J.5
Buyske, S.6
Carlson, C.S.7
Rosse, S.8
Buzkova, P.9
Fornage, M.10
Gross, M.11
Pankratz, N.12
Pankow, J.S.13
Schreiner, P.J.14
Cooper, R.15
Ehret, G.16
Gu, C.C.17
Houston, D.18
Irvin, M.R.19
Jackson, R.20
Kuller, L.21
Henderson, B.22
Cheng, I.23
Wilkens, L.24
Leppert, M.25
Lewis, C.E.26
Li, R.27
Nguyen, K.D.28
Goodloe, R.29
Farber-Eger, E.30
Boston, J.31
Dilks, H.H.32
Ritchie, M.D.33
Fowke, J.34
Pooler, L.35
Graff, M.36
Fernandez-Rhodes, L.37
Cochrane, B.38
Boerwinkle, E.39
Kooperberg, C.40
Matise, T.C.41
Le Marchand, L.42
Crawford, D.C.43
Haiman, C.A.44
North, K.E.45
Peters, U.46
more..
-
76
-
-
84868337361
-
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
-
Morris A.P., Voight B.F., Teslovich T.M., Ferreira T., Segre A.V., Steinthorsdottir V., Strawbridge R.J., Khan H., Grallert H., Mahajan A., Prokopenko I., Kang H.M., Dina C., Esko T., Fraser R.M., Kanoni S., Kumar A., Lagou V., Langenberg C., Luan J., Lindgren C.M., Muller-Nurasyid M., Pechlivanis S., Rayner N.W., Scott L.J., Wiltshire S., Yengo L., Kinnunen L., Rossin E.J., Raychaudhuri S., Johnson A.D., Dimas A.S., Loos R.J., Vedantam S., Chen H., Florez J.C., Fox C., Liu C.T., Rybin D., Couper D.J., Kao W.H., Li M., Cornelis M.C., Kraft P., Sun Q., van Dam R.M., Stringham H.M., Chines P.S., Fischer K., Fontanillas P., Holmen O.L., Hunt S.E., Jackson A.U., Kong A., Lawrence R., Meyer J., Perry J.R., Platou C.G., Potter S., Rehnberg E., Robertson N., Sivapalaratnam S., Stancakova A., Stirrups K., Thorleifsson G., Tikkanen E., Wood A.R., Almgren P., Atalay M., Benediktsson R., Bonnycastle L.L., Burtt N., Carey J., Charpentier G., Crenshaw A.T., Doney A.S., Dorkhan M., Edkins S., Emilsson V., Eury E., Forsen T., Gertow K., Gigante B., Grant G.B., Groves C.J., Guiducci C., Herder C., Hreidarsson A.B., Hui J., James A., Jonsson A., Rathmann W., Klopp N., Kravic J., Krjutskov K., Langford C., Leander K., Lindholm E., Lobbens S., Mannisto S., Mirza G., Muhleisen T.W., Musk B., Parkin M., Rallidis L., Saramies J., Sennblad B., Shah S., Sigurethsson G., Silveira A., Steinbach G., Thorand B., Trakalo J., Veglia F., Wennauer R., Winckler W., Zabaneh D., Campbell H., van Duijn C., Uitterlinden A.G., Hofman A., Sijbrands E., Abecasis G.R., Owen K.R., Zeggini E., Trip M.D., Forouhi N.G., Syvanen A.C., Eriksson J.G., Peltonen L., Nothen M.M., Balkau B., Palmer C.N., Lyssenko V., Tuomi T., Isomaa B., Hunter D.J., Qi L., Wellcome Trust Case Control Consortium, Meta-Analyses of Glucose and Insulin-related Traits Consortium (MAGIC) Investigators, Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Asian Genetic Epidemiology Network-Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Shuldiner A.R., Roden M., Barroso I., Wilsgaard T., Beilby J., Hovingh K., Price J.F., Wilson J.F., Rauramaa R., Lakka T.A., Lind L., Dedoussis G., Njolstad I., Pedersen N.L., Khaw K.T., Wareham N.J., Keinanen-Kiukaanniemi S.M., Saaristo T.E., Korpi-Hyovalti E., Saltevo J., Laakso M., Kuusisto J., Metspalu A., Collins F.S., Mohlke K.L., Bergman R.N., Tuomilehto J., Boehm B.O., Gieger C., Hveem K., Cauchi S., Froguel P., Baldassarre D., Tremoli E., Humphries S.E., Saleheen D., Danesh J., Ingelsson E., Ripatti S., Salomaa V., Erbel R., Jockel K.H., Moebus S., Peters A., Illig T., de Faire U., Hamsten A., Morris A.D., Donnelly P.J., Frayling T.M., Hattersley A.T., Boerwinkle E., Melander O., Kathiresan S., Nilsson P.M., Deloukas P., Thorsteinsdottir U., Groop L.C., Stefansson K., Hu F., Pankow J.S., Dupuis J., Meigs J.B., Altshuler D., Boehnke M., McCarthy M.I., D.I.G.Replication, C.Meta-analysis Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat. Genet. 2012, 44:981-990.
-
(2012)
Nat. Genet.
, vol.44
, pp. 981-990
-
-
Morris, A.P.1
Voight, B.F.2
Teslovich, T.M.3
Ferreira, T.4
Segre, A.V.5
Steinthorsdottir, V.6
Strawbridge, R.J.7
Khan, H.8
Grallert, H.9
Mahajan, A.10
Prokopenko, I.11
Kang, H.M.12
Dina, C.13
Esko, T.14
Fraser, R.M.15
Kanoni, S.16
Kumar, A.17
Lagou, V.18
Langenberg, C.19
Luan, J.20
Lindgren, C.M.21
Muller-Nurasyid, M.22
Pechlivanis, S.23
Rayner, N.W.24
Scott, L.J.25
Wiltshire, S.26
Yengo, L.27
Kinnunen, L.28
Rossin, E.J.29
Raychaudhuri, S.30
Johnson, A.D.31
Dimas, A.S.32
Loos, R.J.33
Vedantam, S.34
Chen, H.35
Florez, J.C.36
Fox, C.37
Liu, C.T.38
Rybin, D.39
Couper, D.J.40
Kao, W.H.41
Li, M.42
Cornelis, M.C.43
Kraft, P.44
Sun, Q.45
van Dam, R.M.46
Stringham, H.M.47
Chines, P.S.48
Fischer, K.49
Fontanillas, P.50
Holmen, O.L.51
Hunt, S.E.52
Jackson, A.U.53
Kong, A.54
Lawrence, R.55
Meyer, J.56
Perry, J.R.57
Platou, C.G.58
Potter, S.59
Rehnberg, E.60
Robertson, N.61
Sivapalaratnam, S.62
Stancakova, A.63
Stirrups, K.64
Thorleifsson, G.65
Tikkanen, E.66
Wood, A.R.67
Almgren, P.68
Atalay, M.69
Benediktsson, R.70
Bonnycastle, L.L.71
Burtt, N.72
Carey, J.73
Charpentier, G.74
Crenshaw, A.T.75
Doney, A.S.76
Dorkhan, M.77
Edkins, S.78
Emilsson, V.79
Eury, E.80
Forsen, T.81
Gertow, K.82
Gigante, B.83
Grant, G.B.84
Groves, C.J.85
Guiducci, C.86
Herder, C.87
Hreidarsson, A.B.88
Hui, J.89
James, A.90
Jonsson, A.91
Rathmann, W.92
Klopp, N.93
Kravic, J.94
Krjutskov, K.95
Langford, C.96
Leander, K.97
Lindholm, E.98
Lobbens, S.99
more..
-
77
-
-
84865693929
-
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
-
Scott R.A., Lagou V., Welch R.P., Wheeler E., Montasser M.E., Luan J., Magi R., Strawbridge R.J., Rehnberg E., Gustafsson S., Kanoni S., Rasmussen-Torvik L.J., Yengo L., Lecoeur C., Shungin D., Sanna S., Sidore C., Johnson P.C., Jukema J.W., Johnson T., Mahajan A., Verweij N., Thorleifsson G., Hottenga J.J., Shah S., Smith A.V., Sennblad B., Gieger C., Salo P., Perola M., Timpson N.J., Evans D.M., Pourcain B.S., Wu Y., Andrews J.S., Hui J., Bielak L.F., Zhao W., Horikoshi M., Navarro P., Isaacs A., O'Connell J.R., Stirrups K., Vitart V., Hayward C., Esko T., Mihailov E., Fraser R.M., Fall T., Voight B.F., Raychaudhuri S., Chen H., Lindgren C.M., Morris A.P., Rayner N.W., Robertson N., Rybin D., Liu C.T., Beckmann J.S., Willems S.M., Chines P.S., Jackson A.U., Kang H.M., Stringham H.M., Song K., Tanaka T., Peden J.F., Goel A., Hicks A.A., An P., Muller-Nurasyid M., Franco-Cereceda A., Folkersen L., Marullo L., Jansen H., Oldehinkel A.J., Bruinenberg M., Pankow J.S., North K.E., Forouhi N.G., Loos R.J., Edkins S., Varga T.V., Hallmans G., Oksa H., Antonella M., Nagaraja R., Trompet S., Ford I., Bakker S.J., Kong A., Kumari M., Gigante B., Herder C., Munroe P.B., Caulfield M., Antti J., Mangino M., Small K., Miljkovic I., Liu Y., Atalay M., Kiess W., James A.L., Rivadeneira F., Uitterlinden A.G., Palmer C.N., Doney A.S., Willemsen G., Smit J.H., Campbell S., Polasek O., Bonnycastle L.L., Hercberg S., Dimitriou M., Bolton J.L., Fowkes G.R., Kovacs P., Lindstrom J., Zemunik T., Bandinelli S., Wild S.H., Basart H.V., Rathmann W., Grallert H., D.I.G.Replication, C.Meta-analysis, Maerz W., Kleber M.E., Boehm B.O., Peters A., Pramstaller P.P., Province M.A., Borecki I.B., Hastie N.D., Rudan I., Campbell H., Watkins H., Farrall M., Stumvoll M., Ferrucci L., Waterworth D.M., Bergman R.N., Collins F.S., Tuomilehto J., Watanabe R.M., de Geus E.J., Penninx B.W., Hofman A., Oostra B.A., Psaty B.M., Vollenweider P., Wilson J.F., Wright A.F., Hovingh G.K., Metspalu A., Uusitupa M., Magnusson P.K., Kyvik K.O., Kaprio J., Price J.F., Dedoussis G.V., Deloukas P., Meneton P., Lind L., Boehnke M., Shuldiner A.R., van Duijn C.M., Morris A.D., Toenjes A., Peyser P.A., Beilby J.P., Korner A., Kuusisto J., Laakso M., Bornstein S.R., Schwarz P.E., Lakka T.A., Rauramaa R., Adair L.S., Smith G.D., Spector T.D., Illig T., de Faire U., Hamsten A., Gudnason V., Kivimaki M., Hingorani A., Keinanen-Kiukaanniemi S.M., Saaristo T.E., Boomsma D.I., Stefansson K., van der Harst P., Dupuis J., Pedersen N.L., Sattar N., Harris T.B., Cucca F., Ripatti S., Salomaa V., Mohlke K.L., Balkau B., Froguel P., Pouta A., Jarvelin M.R., Wareham N.J., Bouatia-Naji N., McCarthy M.I., Franks P.W., Meigs J.B., Teslovich T.M., Florez J.C., Langenberg C., Ingelsson E., Prokopenko I., Barroso I. Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat. Genet. 2012, 44:991-1005.
-
(2012)
Nat. Genet.
, vol.44
, pp. 991-1005
-
-
Scott, R.A.1
Lagou, V.2
Welch, R.P.3
Wheeler, E.4
Montasser, M.E.5
Luan, J.6
Magi, R.7
Strawbridge, R.J.8
Rehnberg, E.9
Gustafsson, S.10
Kanoni, S.11
Rasmussen-Torvik, L.J.12
Yengo, L.13
Lecoeur, C.14
Shungin, D.15
Sanna, S.16
Sidore, C.17
Johnson, P.C.18
Jukema, J.W.19
Johnson, T.20
Mahajan, A.21
Verweij, N.22
Thorleifsson, G.23
Hottenga, J.J.24
Shah, S.25
Smith, A.V.26
Sennblad, B.27
Gieger, C.28
Salo, P.29
Perola, M.30
Timpson, N.J.31
Evans, D.M.32
Pourcain, B.S.33
Wu, Y.34
Andrews, J.S.35
Hui, J.36
Bielak, L.F.37
Zhao, W.38
Horikoshi, M.39
Navarro, P.40
Isaacs, A.41
O'Connell, J.R.42
Stirrups, K.43
Vitart, V.44
Hayward, C.45
Esko, T.46
Mihailov, E.47
Fraser, R.M.48
Fall, T.49
Voight, B.F.50
Raychaudhuri, S.51
Chen, H.52
Lindgren, C.M.53
Morris, A.P.54
Rayner, N.W.55
Robertson, N.56
Rybin, D.57
Liu, C.T.58
Beckmann, J.S.59
Willems, S.M.60
Chines, P.S.61
Jackson, A.U.62
Kang, H.M.63
Stringham, H.M.64
Song, K.65
Tanaka, T.66
Peden, J.F.67
Goel, A.68
Hicks, A.A.69
An, P.70
Muller-Nurasyid, M.71
Franco-Cereceda, A.72
Folkersen, L.73
Marullo, L.74
Jansen, H.75
Oldehinkel, A.J.76
Bruinenberg, M.77
Pankow, J.S.78
North, K.E.79
Forouhi, N.G.80
Loos, R.J.81
Edkins, S.82
Varga, T.V.83
Hallmans, G.84
Oksa, H.85
Antonella, M.86
Nagaraja, R.87
Trompet, S.88
Ford, I.89
Bakker, S.J.90
Kong, A.91
Kumari, M.92
Gigante, B.93
Herder, C.94
Munroe, P.B.95
Caulfield, M.96
Antti, J.97
Mangino, M.98
Small, K.99
more..
-
78
-
-
84875996758
-
Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained
-
Wu Y., Waite L.L., Jackson A.U., Sheu W.H., Buyske S., Absher D., Arnett D.K., Boerwinkle E., Bonnycastle L.L., Carty C.L., Cheng I., Cochran B., Croteau-Chonka D.C., Dumitrescu L., Eaton C.B., Franceschini N., Guo X., Henderson B.E., Hindorff L.A., Kim E., Kinnunen L., Komulainen P., Lee W.J., Le Marchand L., Lin Y., Lindstrom J., Lingaas-Holmen O., Mitchell S.L., Narisu N., Robinson J.G., Schumacher F., Stancakova A., Sundvall J., Sung Y.J., Swift A.J., Wang W.C., Wilkens L., Wilsgaard T., Young A.M., Adair L.S., Ballantyne C.M., Buzkova P., Chakravarti A., Collins F.S., Duggan D., Feranil A.B., Ho L.T., Hung Y.J., Hunt S.C., Hveem K., Juang J.M., Kesaniemi A.Y., Kuusisto J., Laakso M., Lakka T.A., Lee I.T., Leppert M.F., Matise T.C., Moilanen L., Njolstad I., Peters U., Quertermous T., Rauramaa R., Rotter J.I., Saramies J., Tuomilehto J., Uusitupa M., Wang T.D., Boehnke M., Haiman C.A., Chen Y.D., Kooperberg C., Assimes T.L., Crawford D.C., Hsiung C.A., North K.E., Mohlke K.L. Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. PLoS Genet. 2013, 9:e1003379.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003379
-
-
Wu, Y.1
Waite, L.L.2
Jackson, A.U.3
Sheu, W.H.4
Buyske, S.5
Absher, D.6
Arnett, D.K.7
Boerwinkle, E.8
Bonnycastle, L.L.9
Carty, C.L.10
Cheng, I.11
Cochran, B.12
Croteau-Chonka, D.C.13
Dumitrescu, L.14
Eaton, C.B.15
Franceschini, N.16
Guo, X.17
Henderson, B.E.18
Hindorff, L.A.19
Kim, E.20
Kinnunen, L.21
Komulainen, P.22
Lee, W.J.23
Le Marchand, L.24
Lin, Y.25
Lindstrom, J.26
Lingaas-Holmen, O.27
Mitchell, S.L.28
Narisu, N.29
Robinson, J.G.30
Schumacher, F.31
Stancakova, A.32
Sundvall, J.33
Sung, Y.J.34
Swift, A.J.35
Wang, W.C.36
Wilkens, L.37
Wilsgaard, T.38
Young, A.M.39
Adair, L.S.40
Ballantyne, C.M.41
Buzkova, P.42
Chakravarti, A.43
Collins, F.S.44
Duggan, D.45
Feranil, A.B.46
Ho, L.T.47
Hung, Y.J.48
Hunt, S.C.49
Hveem, K.50
Juang, J.M.51
Kesaniemi, A.Y.52
Kuusisto, J.53
Laakso, M.54
Lakka, T.A.55
Lee, I.T.56
Leppert, M.F.57
Matise, T.C.58
Moilanen, L.59
Njolstad, I.60
Peters, U.61
Quertermous, T.62
Rauramaa, R.63
Rotter, J.I.64
Saramies, J.65
Tuomilehto, J.66
Uusitupa, M.67
Wang, T.D.68
Boehnke, M.69
Haiman, C.A.70
Chen, Y.D.71
Kooperberg, C.72
Assimes, T.L.73
Crawford, D.C.74
Hsiung, C.A.75
North, K.E.76
Mohlke, K.L.77
more..
-
79
-
-
0037603589
-
Mutations in PCSK9 cause autosomal dominant hypercholesterolemia
-
Abifadel M., Varret M., Rabes J.P., Allard D., Ouguerram K., Devillers M., Cruaud C., Benjannet S., Wickham L., Erlich D., Derre A., Villeger L., Farnier M., Beucler I., Bruckert E., Chambaz J., Chanu B., Lecerf J.M., Luc G., Moulin P., Weissenbach J., Prat A., Krempf M., Junien C., Seidah N.G., Boileau C. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia. Nat. Genet. 2003, 34:154-156.
-
(2003)
Nat. Genet.
, vol.34
, pp. 154-156
-
-
Abifadel, M.1
Varret, M.2
Rabes, J.P.3
Allard, D.4
Ouguerram, K.5
Devillers, M.6
Cruaud, C.7
Benjannet, S.8
Wickham, L.9
Erlich, D.10
Derre, A.11
Villeger, L.12
Farnier, M.13
Beucler, I.14
Bruckert, E.15
Chambaz, J.16
Chanu, B.17
Lecerf, J.M.18
Luc, G.19
Moulin, P.20
Weissenbach, J.21
Prat, A.22
Krempf, M.23
Junien, C.24
Seidah, N.G.25
Boileau, C.26
more..
-
80
-
-
13944265645
-
Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9
-
Cohen J., Pertsemlidis A., Kotowski I.K., Graham R., Garcia C.K., Hobbs H.H. Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9. Nat. Genet. 2005, 37:161-165.
-
(2005)
Nat. Genet.
, vol.37
, pp. 161-165
-
-
Cohen, J.1
Pertsemlidis, A.2
Kotowski, I.K.3
Graham, R.4
Garcia, C.K.5
Hobbs, H.H.6
-
81
-
-
33645103550
-
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
-
Cohen J.C., Boerwinkle E., Mosley T.H., Hobbs H.H. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N. Engl. J. Med. 2006, 354:1264-1272.
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 1264-1272
-
-
Cohen, J.C.1
Boerwinkle, E.2
Mosley, T.H.3
Hobbs, H.H.4
-
82
-
-
84897889156
-
PCSK9: a key modulator of cardiovascular health
-
Seidah N.G., Awan Z., Chretien M., Mbikay M. PCSK9: a key modulator of cardiovascular health. Circ. Res. 2014, 114:1022-1036.
-
(2014)
Circ. Res.
, vol.114
, pp. 1022-1036
-
-
Seidah, N.G.1
Awan, Z.2
Chretien, M.3
Mbikay, M.4
-
83
-
-
71249103564
-
Principal-component-based population structure adjustment in the North American Rheumatoid Arthritis Consortium data: impact of single-nucleotide polymorphism set and analysis method
-
Peloso G.M., Timofeev N., Lunetta K.L. Principal-component-based population structure adjustment in the North American Rheumatoid Arthritis Consortium data: impact of single-nucleotide polymorphism set and analysis method. BMC Proc. 2009, 3(Suppl. 7):S108.
-
(2009)
BMC Proc.
, vol.3
, Issue.7 SUPPL
, pp. S108
-
-
Peloso, G.M.1
Timofeev, N.2
Lunetta, K.L.3
-
84
-
-
84893756641
-
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks
-
Peloso G.M., Auer P.L., Bis J.C., Voorman A., Morrison A.C., Stitziel N.O., Brody J.A., Khetarpal S.A., Crosby J.R., Fornage M., Isaacs A., Jakobsdottir J., Feitosa M.F., Davies G., Huffman J.E., Manichaikul A., Davis B., Lohman K., Joon A.Y., Smith A.V., Grove M.L., Zanoni P., Redon V., Demissie S., Lawson K., Peters U., Carlson C., Jackson R.D., Ryckman K.K., Mackey R.H., Robinson J.G., Siscovick D.S., Schreiner P.J., Mychaleckyj J.C., Pankow J.S., Hofman A., Uitterlinden A.G., Harris T.B., Taylor K.D., Stafford J.M., Reynolds L.M., Marioni R.E., Dehghan A., Franco O.H., Patel A.P., Lu Y., Hindy G., Gottesman O., Bottinger E.P., Melander O., Orho-Melander M., Loos R.J., Duga S., Merlini P.A., Farrall M., Goel A., Asselta R., Girelli D., Martinelli N., Shah S.H., Kraus W.E., Li M., Rader D.J., Reilly M.P., McPherson R., Watkins H., Ardissino D., Project N.G.E.S., Zhang Q., Wang J., Tsai M.Y., Taylor H.A., Correa A., Griswold M.E., Lange L.A., Starr J.M., Rudan I., Eiriksdottir G., Launer L.J., Ordovas J.M., Levy D., Chen Y.D., Reiner A.P., Hayward C., Polasek O., Deary I.J., Borecki I.B., Liu Y., Gudnason V., Wilson J.G., van Duijn C.M., Kooperberg C., Rich S.S., Psaty B.M., Rotter J.I., O'Donnell C.J., Rice K., Boerwinkle E., Kathiresan S., Cupples L.A. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. Am. J. Hum. Genet. 2014, 94:223-232.
-
(2014)
Am. J. Hum. Genet.
, vol.94
, pp. 223-232
-
-
Peloso, G.M.1
Auer, P.L.2
Bis, J.C.3
Voorman, A.4
Morrison, A.C.5
Stitziel, N.O.6
Brody, J.A.7
Khetarpal, S.A.8
Crosby, J.R.9
Fornage, M.10
Isaacs, A.11
Jakobsdottir, J.12
Feitosa, M.F.13
Davies, G.14
Huffman, J.E.15
Manichaikul, A.16
Davis, B.17
Lohman, K.18
Joon, A.Y.19
Smith, A.V.20
Grove, M.L.21
Zanoni, P.22
Redon, V.23
Demissie, S.24
Lawson, K.25
Peters, U.26
Carlson, C.27
Jackson, R.D.28
Ryckman, K.K.29
Mackey, R.H.30
Robinson, J.G.31
Siscovick, D.S.32
Schreiner, P.J.33
Mychaleckyj, J.C.34
Pankow, J.S.35
Hofman, A.36
Uitterlinden, A.G.37
Harris, T.B.38
Taylor, K.D.39
Stafford, J.M.40
Reynolds, L.M.41
Marioni, R.E.42
Dehghan, A.43
Franco, O.H.44
Patel, A.P.45
Lu, Y.46
Hindy, G.47
Gottesman, O.48
Bottinger, E.P.49
Melander, O.50
Orho-Melander, M.51
Loos, R.J.52
Duga, S.53
Merlini, P.A.54
Farrall, M.55
Goel, A.56
Asselta, R.57
Girelli, D.58
Martinelli, N.59
Shah, S.H.60
Kraus, W.E.61
Li, M.62
Rader, D.J.63
Reilly, M.P.64
McPherson, R.65
Watkins, H.66
Ardissino, D.67
Project, N.G.E.S.68
Zhang, Q.69
Wang, J.70
Tsai, M.Y.71
Taylor, H.A.72
Correa, A.73
Griswold, M.E.74
Lange, L.A.75
Starr, J.M.76
Rudan, I.77
Eiriksdottir, G.78
Launer, L.J.79
Ordovas, J.M.80
Levy, D.81
Chen, Y.D.82
Reiner, A.P.83
Hayward, C.84
Polasek, O.85
Deary, I.J.86
Borecki, I.B.87
Liu, Y.88
Gudnason, V.89
Wilson, J.G.90
van Duijn, C.M.91
Kooperberg, C.92
Rich, S.S.93
Psaty, B.M.94
Rotter, J.I.95
O'Donnell, C.J.96
Rice, K.97
Boerwinkle, E.98
Kathiresan, S.99
more..
-
85
-
-
84898058547
-
Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk
-
Holmen O.L., Zhang H., Fan Y., Hovelson D.H., Schmidt E.M., Zhou W., Guo Y., Zhang J., Langhammer A., Lochen M.L., Ganesh S.K., Vatten L., Skorpen F., Dalen H., Zhang J., Pennathur S., Chen J., Platou C., Mathiesen E.B., Wilsgaard T., Njolstad I., Boehnke M., Chen Y.E., Abecasis G.R., Hveem K., Willer C.J. Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk. Nat. Genet. 2014, 46:345-351.
-
(2014)
Nat. Genet.
, vol.46
, pp. 345-351
-
-
Holmen, O.L.1
Zhang, H.2
Fan, Y.3
Hovelson, D.H.4
Schmidt, E.M.5
Zhou, W.6
Guo, Y.7
Zhang, J.8
Langhammer, A.9
Lochen, M.L.10
Ganesh, S.K.11
Vatten, L.12
Skorpen, F.13
Dalen, H.14
Zhang, J.15
Pennathur, S.16
Chen, J.17
Platou, C.18
Mathiesen, E.B.19
Wilsgaard, T.20
Njolstad, I.21
Boehnke, M.22
Chen, Y.E.23
Abecasis, G.R.24
Hveem, K.25
Willer, C.J.26
more..
-
86
-
-
52949135179
-
Strengthening causal inference in cardiovascular epidemiology through Mendelian randomization
-
Smith G.D., Timpson N., Ebrahim S. Strengthening causal inference in cardiovascular epidemiology through Mendelian randomization. Ann. Med. 2008, 40:524-541.
-
(2008)
Ann. Med.
, vol.40
, pp. 524-541
-
-
Smith, G.D.1
Timpson, N.2
Ebrahim, S.3
-
87
-
-
67049137261
-
Mendelian randomization: nature's randomized trial in the post-genome era
-
Thanassoulis G., O'Donnell C.J. Mendelian randomization: nature's randomized trial in the post-genome era. JAMA 2009, 301:2386-2388.
-
(2009)
JAMA
, vol.301
, pp. 2386-2388
-
-
Thanassoulis, G.1
O'Donnell, C.J.2
-
88
-
-
55249105922
-
Elevated C-reactive protein in atherosclerosis-chicken or egg?
-
Schunkert H., Samani N.J. Elevated C-reactive protein in atherosclerosis-chicken or egg?. N. Engl. J. Med. 2008, 359:1953-1955.
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 1953-1955
-
-
Schunkert, H.1
Samani, N.J.2
-
89
-
-
44649140474
-
Association of loss-of-function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease
-
Frikke-Schmidt R., Nordestgaard B.G., Stene M.C., Sethi A.A., Remaley A.T., Schnohr P., Grande P., Tybjaerg-Hansen A. Association of loss-of-function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease. JAMA 2008, 299:2524-2532.
-
(2008)
JAMA
, vol.299
, pp. 2524-2532
-
-
Frikke-Schmidt, R.1
Nordestgaard, B.G.2
Stene, M.C.3
Sethi, A.A.4
Remaley, A.T.5
Schnohr, P.6
Grande, P.7
Tybjaerg-Hansen, A.8
-
90
-
-
84856786437
-
LCAT, HDL cholesterol and ischemic cardiovascular disease: a Mendelian randomization study of HDL cholesterol in 54,500 individuals
-
Haase C.L., Tybjaerg-Hansen A., Qayyum A.A., Schou J., Nordestgaard B.G., Frikke-Schmidt R. LCAT, HDL cholesterol and ischemic cardiovascular disease: a Mendelian randomization study of HDL cholesterol in 54,500 individuals. J. Clin. Endocrinol. Metab. 2012, 97:E248-E256.
-
(2012)
J. Clin. Endocrinol. Metab.
, vol.97
, pp. E248-E256
-
-
Haase, C.L.1
Tybjaerg-Hansen, A.2
Qayyum, A.A.3
Schou, J.4
Nordestgaard, B.G.5
Frikke-Schmidt, R.6
-
91
-
-
65249148632
-
Hepatic lipase, genetically elevated high-density lipoprotein, and risk of ischemic cardiovascular disease
-
Johannsen T.H., Kamstrup P.R., Andersen R.V., Jensen G.B., Sillesen H., Tybjaerg-Hansen A., Nordestgaard B.G. Hepatic lipase, genetically elevated high-density lipoprotein, and risk of ischemic cardiovascular disease. J. Clin. Endocrinol. Metab. 2009, 94:1264-1273.
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, pp. 1264-1273
-
-
Johannsen, T.H.1
Kamstrup, P.R.2
Andersen, R.V.3
Jensen, G.B.4
Sillesen, H.5
Tybjaerg-Hansen, A.6
Nordestgaard, B.G.7
-
92
-
-
67649367650
-
Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study
-
Ridker P.M., Pare G., Parker A.N., Zee R.Y., Miletich J.P., Chasman D.I. Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study. Circ. Cardiovasc. Genet 2009, 2:26-33.
-
(2009)
Circ. Cardiovasc. Genet
, vol.2
, pp. 26-33
-
-
Ridker, P.M.1
Pare, G.2
Parker, A.N.3
Zee, R.Y.4
Miletich, J.P.5
Chasman, D.I.6
-
93
-
-
84887058576
-
Common variants associated with plasma triglycerides and risk for coronary artery disease
-
Do R., Willer C.J., Schmidt E.M., Sengupta S., Gao C., Peloso G.M., Gustafsson S., Kanoni S., Ganna A., Chen J., Buchkovich M.L., Mora S., Beckmann J.S., Bragg-Gresham J.L., Chang H.Y., Demirkan A., Den Hertog H.M., Donnelly L.A., Ehret G.B., Esko T., Feitosa M.F., Ferreira T., Fischer K., Fontanillas P., Fraser R.M., Freitag D.F., Gurdasani D., Heikkila K., Hypponen E., Isaacs A., Jackson A.U., Johansson A., Johnson T., Kaakinen M., Kettunen J., Kleber M.E., Li X., Luan J., Lyytikainen L.P., Magnusson P.K., Mangino M., Mihailov E., Montasser M.E., Muller-Nurasyid M., Nolte I.M., O'Connell J.R., Palmer C.D., Perola M., Petersen A.K., Sanna S., Saxena R., S.K.Service, Shah S., Shungin D., Sidore C., Song C., Strawbridge R.J., Surakka I., Tanaka T., Teslovich T.M., Thorleifsson G., Van den Herik E.G., Voight B.F., Volcik K.A., Waite L.L., Wong A., Wu Y., Zhang W., Absher D., Asiki G., Barroso I., Been L.F., Bolton J.L., Bonnycastle L.L., Brambilla P., Burnett M.S., Cesana G., Dimitriou M., Doney A.S., Doring A., Elliott P., Epstein S.E., Eyjolfsson G.I., Gigante B., Goodarzi M.O., Grallert H., Gravito M.L., Groves C.J., Hallmans G., Hartikainen A.L., Hayward C., Hernandez D., Hicks A.A., Holm H., Hung Y.J., Illig T., Jones M.R., Kaleebu P., Kastelein J.J., Khaw K.T., Kim E., Klopp N., Komulainen P., Kumari M., Langenberg C., Lehtimaki T., Lin S.Y., Lindstrom J., Loos R.J., Mach F., McArdle W.L., Meisinger C., Mitchell B.D., Muller G., Nagaraja R., Narisu N., Nieminen T.V., Nsubuga R.N., Olafsson I., Ong K.K., Palotie A., Papamarkou T., Pomilla C., Pouta A., Rader D.J., Reilly M.P., Ridker P.M., Rivadeneira F., Rudan I., Ruokonen A., Samani N., Scharnagl H., Seeley J., Silander K., Stancakova A., Stirrups K., Swift A.J., Tiret L., Uitterlinden A.G., van Pelt L.J., Vedantam S., Wainwright N., Wijmenga C., Wild S.H., Willemsen G., Wilsgaard T., Wilson J.F., Young E.H., Zhao J.H., Adair L.S., Arveiler D., Assimes T.L., Bandinelli S., Bennett F., Bochud M., Boehm B.O., Boomsma D.I., Borecki I.B., Bornstein S.R., Bovet P., Burnier M., Campbell H., Chakravarti A., Chambers J.C., Chen Y.D., Collins F.S., Cooper R.S., Danesh J., Dedoussis G., de Faire U., Feranil A.B., Ferrieres J., Ferrucci L., Freimer N.B., Gieger C., Groop L.C., Gudnason V., Gyllensten U., Hamsten A., Harris T.B., Hingorani A., Hirschhorn J.N., Hofman A., Hovingh G.K., Hsiung C.A., Humphries S.E., Hunt S.C., Hveem K., Iribarren C., Jarvelin M.R., Jula A., Kahonen M., Kaprio J., Kesaniemi A., Kivimaki M., Kooner J.S., Koudstaal P.J., Krauss R.M., Kuh D., Kuusisto J., Kyvik K.O., Laakso M., Lakka T.A., Lind L., Lindgren C.M., Martin N.G., Marz W., McCarthy M.I., McKenzie C.A., Meneton P., Metspalu A., Moilanen L., Morris A.D., Munroe P.B., Njolstad I., Pedersen N.L., Power C., Pramstaller P.P., Price J.F., Psaty B.M., Quertermous T., Rauramaa R., Saleheen D., Salomaa V., Sanghera D.K., Saramies J., Schwarz P.E., Sheu W.H., Shuldiner A.R., Siegbahn A., Spector T.D., Stefansson K., Strachan D.P., Tayo B.O., Tremoli E., Tuomilehto J., Uusitupa M., van Duijn C.M., Vollenweider P., Wallentin L., Wareham N.J., Whitfield J.B., Wolffenbuttel B.H., Altshuler D., Ordovas J.M., Boerwinkle E., Palmer C.N., Thorsteinsdottir U., Chasman D.I., Rotter J.I., Franks P.W., Ripatti S., Cupples L.A., Sandhu M.S., Rich S.S., Boehnke M., Deloukas P., Mohlke K.L., Ingelsson E., Abecasis G.R., Daly M.J., Neale B.M., Kathiresan S. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat. Genet. 2013, 45:1345-1352.
-
(2013)
Nat. Genet.
, vol.45
, pp. 1345-1352
-
-
Do, R.1
Schmidt, E.M.2
Gao, C.3
Gustafsson, S.4
Ganna, A.5
Buchkovich, M.L.6
Beckmann, J.S.7
Chang, H.Y.8
Den Hertog, H.M.9
Ehret, G.B.10
Feitosa, M.F.11
Fischer, K.12
Fraser, R.M.13
Gurdasani, D.14
Hypponen, E.15
Jackson, A.U.16
Johnson, T.17
Kettunen, J.18
Li, X.19
Lyytikainen, L.P.20
Mangino, M.21
Montasser, M.E.22
Nolte, I.M.23
Palmer, C.D.24
Petersen, A.K.25
Saxena, R.26
Shungin, D.27
Song, C.28
Surakka, I.29
Teslovich, T.M.30
Van den Herik, E.G.31
Volcik, K.A.32
Wong, A.33
Zhang, W.34
Asiki, G.35
Been, L.F.36
Bonnycastle, L.L.37
Burnett, M.S.38
Dimitriou, M.39
Doring, A.40
Epstein, S.E.41
Gigante, B.42
Grallert, H.43
Groves, C.J.44
Hartikainen, A.L.45
Hernandez, D.46
Holm, H.47
Illig, T.48
Kaleebu, P.49
Willer, C.J.50
Sengupta, S.51
Peloso, G.M.52
Kanoni, S.53
Chen, J.54
Mora, S.55
Bragg-Gresham, J.L.56
Demirkan, A.57
Donnelly, L.A.58
Esko, T.59
Ferreira, T.60
Fontanillas, P.61
Freitag, D.F.62
Heikkila, K.63
Isaacs, A.64
Johansson, A.65
Kaakinen, M.66
Kleber, M.E.67
Luan, J.68
Magnusson, P.K.69
Mihailov, E.70
Muller-Nurasyid, M.71
O'Connell, J.R.72
Perola, M.73
Sanna, S.74
Shah, S.75
Sidore, C.76
Strawbridge, R.J.77
Tanaka, T.78
Thorleifsson, G.79
Voight, B.F.80
Waite, L.L.81
Wu, Y.82
Absher, D.83
Barroso, I.84
Bolton, J.L.85
Brambilla, P.86
Cesana, G.87
Doney, A.S.88
Elliott, P.89
Eyjolfsson, G.I.90
Goodarzi, M.O.91
Gravito, M.L.92
Hallmans, G.93
Hayward, C.94
Hicks, A.A.95
Hung, Y.J.96
Jones, M.R.97
Kastelein, J.J.98
more..
-
94
-
-
77955070766
-
Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia
-
Johansen C.T., Wang J., Lanktree M.B., Cao H., McIntyre A.D., Ban M.R., Martins R.A., Kennedy B.A., Hassell R.G., Visser M.E., Schwartz S.M., Voight B.F., Elosua R., Salomaa V., O'Donnell C.J., Dallinga-Thie G.M., Anand S.S., Yusuf S., Huff M.W., Kathiresan S., Hegele R.A. Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. Nat. Genet. 2010, 42:684-687.
-
(2010)
Nat. Genet.
, vol.42
, pp. 684-687
-
-
Johansen, C.T.1
Wang, J.2
Lanktree, M.B.3
Cao, H.4
McIntyre, A.D.5
Ban, M.R.6
Martins, R.A.7
Kennedy, B.A.8
Hassell, R.G.9
Visser, M.E.10
Schwartz, S.M.11
Voight, B.F.12
Elosua, R.13
Salomaa, V.14
O'Donnell, C.J.15
Dallinga-Thie, G.M.16
Anand, S.S.17
Yusuf, S.18
Huff, M.W.19
Kathiresan, S.20
Hegele, R.A.21
more..
-
95
-
-
84879088930
-
Evidence of a polygenic origin of extreme high-density lipoprotein cholesterol levels
-
Motazacker M.M., Peter J., Treskes M., Shoulders C.C., Kuivenhoven J.A., Hovingh G.K. Evidence of a polygenic origin of extreme high-density lipoprotein cholesterol levels. Arterioscler. Thromb. Vasc. Biol. 2013, 33:1521-1528.
-
(2013)
Arterioscler. Thromb. Vasc. Biol.
, vol.33
, pp. 1521-1528
-
-
Motazacker, M.M.1
Peter, J.2
Treskes, M.3
Shoulders, C.C.4
Kuivenhoven, J.A.5
Hovingh, G.K.6
-
96
-
-
78649755576
-
Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia
-
Musunuru K., Pirruccello J.P., Do R., Peloso G.M., Guiducci C., Sougnez C., Garimella K.V., Fisher S., Abreu J., Barry A.J., Fennell T., Banks E., Ambrogio L., Cibulskis K., Kernytsky A., Gonzalez E., Rudzicz N., Engert J.C., DePristo M.A., Daly M.J., Cohen J.C., Hobbs H.H., Altshuler D., Schonfeld G., Gabriel S.B., Yue P., Kathiresan S. Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia. N. Engl. J. Med. 2010, 363:2220-2227.
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 2220-2227
-
-
Musunuru, K.1
Pirruccello, J.P.2
Do, R.3
Peloso, G.M.4
Guiducci, C.5
Sougnez, C.6
Garimella, K.V.7
Fisher, S.8
Abreu, J.9
Barry, A.J.10
Fennell, T.11
Banks, E.12
Ambrogio, L.13
Cibulskis, K.14
Kernytsky, A.15
Gonzalez, E.16
Rudzicz, N.17
Engert, J.C.18
DePristo, M.A.19
Daly, M.J.20
Cohen, J.C.21
Hobbs, H.H.22
Altshuler, D.23
Schonfeld, G.24
Gabriel, S.B.25
Yue, P.26
Kathiresan, S.27
more..
-
97
-
-
84888201938
-
Blood Institute Exome sequencing and directed clinical phenotyping diagnose cholesterol ester storage disease presenting as autosomal recessive hypercholesterolemia
-
Stitziel N.O., Fouchier S.W., Sjouke B., Peloso G.M., Moscoso A.M., Auer P.L., Goel A., Gigante B., Barnes T.A., Melander O., Orho-Melander M., Duga S., Sivapalaratnam S., Nikpay M., Martinelli N., Girelli D., Jackson R.D., Kooperberg C., Lange L.A., Ardissino D., McPherson R., Farrall M., Watkins H., Reilly M.P., Rader D.J., de Faire U., Schunkert H., Erdmann J., Samani N.J., Charnas L., Altshuler D., Gabriel S., Kastelein J.J., Defesche J.C., Nederveen A.J., Kathiresan S., Hovingh G.K., L.National Heart, G.O.E.S.P.Blood Institute Exome sequencing and directed clinical phenotyping diagnose cholesterol ester storage disease presenting as autosomal recessive hypercholesterolemia. Arterioscler. Thromb. Vasc. Biol. 2013, 33:2909-2914.
-
(2013)
Arterioscler. Thromb. Vasc. Biol.
, vol.33
, pp. 2909-2914
-
-
Stitziel, N.O.1
Fouchier, S.W.2
Sjouke, B.3
Peloso, G.M.4
Moscoso, A.M.5
Auer, P.L.6
Goel, A.7
Gigante, B.8
Barnes, T.A.9
Melander, O.10
Orho-Melander, M.11
Duga, S.12
Sivapalaratnam, S.13
Nikpay, M.14
Martinelli, N.15
Girelli, D.16
Jackson, R.D.17
Kooperberg, C.18
Lange, L.A.19
Ardissino, D.20
McPherson, R.21
Farrall, M.22
Watkins, H.23
Reilly, M.P.24
Rader, D.J.25
de Faire, U.26
Schunkert, H.27
Erdmann, J.28
Samani, N.J.29
Charnas, L.30
Altshuler, D.31
Gabriel, S.32
Kastelein, J.J.33
Defesche, J.C.34
Nederveen, A.J.35
Kathiresan, S.36
Hovingh, G.K.37
more..
-
98
-
-
84893720400
-
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol
-
Lange L.A., Hu Y., Zhang H., Xue C., Schmidt E.M., Tang Z.Z., Bizon C., Lange E.M., Smith J.D., Turner E.H., Jun G., Kang H.M., Peloso G., Auer P., Li K.P., Flannick J., Zhang J., Fuchsberger C., Gaulton K., Lindgren C., Locke A., Manning A., Sim X., Rivas M.A., Holmen O.L., Gottesman O., Lu Y., Ruderfer D., Stahl E.A., Duan Q., Li Y., Durda P., Jiao S., Isaacs A., Hofman A., Bis J.C., Correa A., Griswold M.E., Jakobsdottir J., Smith A.V., Schreiner P.J., Feitosa M.F., Zhang Q., Huffman J.E., Crosby J., Wassel C.L., Do R., Franceschini N., Martin L.W., Robinson J.G., Assimes T.L., Crosslin D.R., Rosenthal E.A., Tsai M., Rieder M.J., Farlow D.N., Folsom A.R., Lumley T., Fox E.R., Carlson C.S., Peters U., Jackson R.D., van Duijn C.M., Uitterlinden A.G., Levy D., Rotter J.I., Taylor H.A., Gudnason V., Siscovick D.S., Fornage M., Borecki I.B., Hayward C., Rudan I., Chen Y.E., Bottinger E.P., Loos R.J., Saetrom P., Hveem K., Boehnke M., Groop L., McCarthy M., Meitinger T., Ballantyne C.M., Gabriel S.B., O'Donnell C.J., Post W.S., North K.E., Reiner A.P., Boerwinkle E., Psaty B.M., Altshuler D., Kathiresan S., Lin D.Y., Jarvik G.P., Cupples L.A., Kooperberg C., Wilson J.G., Nickerson D.A., Abecasis G.R., Rich S.S., Tracy R.P., Willer C.J., N.G.O.E.S.Project Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. Am. J. Hum. Genet. 2014, 94:233-245.
-
(2014)
Am. J. Hum. Genet.
, vol.94
, pp. 233-245
-
-
Lange, L.A.1
Hu, Y.2
Zhang, H.3
Xue, C.4
Schmidt, E.M.5
Tang, Z.Z.6
Bizon, C.7
Lange, E.M.8
Smith, J.D.9
Turner, E.H.10
Jun, G.11
Kang, H.M.12
Peloso, G.13
Auer, P.14
Li, K.P.15
Flannick, J.16
Zhang, J.17
Fuchsberger, C.18
Gaulton, K.19
Lindgren, C.20
Locke, A.21
Manning, A.22
Sim, X.23
Rivas, M.A.24
Holmen, O.L.25
Gottesman, O.26
Lu, Y.27
Ruderfer, D.28
Stahl, E.A.29
Duan, Q.30
Li, Y.31
Durda, P.32
Jiao, S.33
Isaacs, A.34
Hofman, A.35
Bis, J.C.36
Correa, A.37
Griswold, M.E.38
Jakobsdottir, J.39
Smith, A.V.40
Schreiner, P.J.41
Feitosa, M.F.42
Zhang, Q.43
Huffman, J.E.44
Crosby, J.45
Wassel, C.L.46
Do, R.47
Franceschini, N.48
Martin, L.W.49
Robinson, J.G.50
Assimes, T.L.51
Crosslin, D.R.52
Rosenthal, E.A.53
Tsai, M.54
Rieder, M.J.55
Farlow, D.N.56
Folsom, A.R.57
Lumley, T.58
Fox, E.R.59
Carlson, C.S.60
Peters, U.61
Jackson, R.D.62
van Duijn, C.M.63
Uitterlinden, A.G.64
Levy, D.65
Rotter, J.I.66
Taylor, H.A.67
Gudnason, V.68
Siscovick, D.S.69
Fornage, M.70
Borecki, I.B.71
Hayward, C.72
Rudan, I.73
Chen, Y.E.74
Bottinger, E.P.75
Loos, R.J.76
Saetrom, P.77
Hveem, K.78
Boehnke, M.79
Groop, L.80
McCarthy, M.81
Meitinger, T.82
Ballantyne, C.M.83
Gabriel, S.B.84
O'Donnell, C.J.85
Post, W.S.86
North, K.E.87
Reiner, A.P.88
Boerwinkle, E.89
Psaty, B.M.90
Altshuler, D.91
Kathiresan, S.92
Lin, D.Y.93
Jarvik, G.P.94
Cupples, L.A.95
Kooperberg, C.96
Wilson, J.G.97
Nickerson, D.A.98
Abecasis, G.R.99
more..
|