Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism

Journal of Clinical Investigation

Volumn 122, Issue 8, 2012, Pages 2807-2816

  Strong, Alanna ^a   Ding, Qiurong ^b   Edmondson, Andrew C ^a   Millar, John S ^a   Sachs, Katherine V ^a   Li, Xiaoyu ^a   Kumaravel, Arthi ^a   Wang, Margaret Ye ^a   Ai, Ding ^c   Guo, Liang ^d   Alexander, Eric T ^e   Nguyen, David ^e   Lund Katz, Sissel ^e   Phillips, Michael C ^e   Morales, Carlos R ^f   Tall, Alan R ^c   Kathiresan, Sekar ^g   Fisher, Edward A ^d   Musunuru, Kiran ^b   Rader, Daniel J ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b HARVARD UNIVERSITY   (United States)

^c NewYork Presbyterian Hospital   (United States)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^f MCGILL UNIVERSITY   (Canada)

^g MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; LOW DENSITY LIPOPROTEIN; SORTILIN;

ANIMAL CELL; ARTICLE; CATABOLISM; CELL MEMBRANE; GOLGI COMPLEX; LIVER LEVEL; LYSOSOME; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN SECRETION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; APOLIPOPROTEINS B; BASE SEQUENCE; CELL LINE; CYTIDINE DEAMINASE; DNA PRIMERS; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL; LIVER; LYSOSOMES; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, LDL; RECOMBINANT PROTEINS;

EID: 84864759987     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI63563     Document Type: Article

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