Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

Nature Genetics

Volumn 43, Issue 11, 2011, Pages 1131-1138

  Chambers, J C ^a   Zhang, W ^a   Sehmi, J S ^a   Li, X ^a   Wass, M N ^a   Van der Harst, P ^a   Holm, H ^a   Sanna, S ^a   Kavousi, M ^a   Baumeister, S E ^a   Coin, L ^a   Deng, G ^a   Gieger, C ^a   Heard Costa, N L ^a   Hottenga, J J ^a   Kuhnel B ^a   Kumar, V ^a   Lagou, V ^a   Liang, L ^a   Luan, J ^a   Vidal, P M ^a   Mateo Leach, I ^a   O'reilly, P F ^a   Peden, J F ^a   Rahmioglu, N ^a   Soininen, P ^a   Speliotes, E K ^a   Yuan, X ^a   Thorleifsson, G ^a   Alizadeh, B Z ^a   Atwood, L D ^a   Borecki, I B ^a   Brown, M J ^a   Charoen, P ^a   Cucca, F ^a   Das, D ^a   de Geus, E J ^a   Dixon, A L ^a   Doring A ^a   Ehret, G B ^a   Eyjolfsson, G I ^a   Farrall, M ^a   Forouhi, N G ^a   Friedrich, N ^a   Goessling, W ^a   Gudbjartsson, D ^a   Harris, T B ^a   Hartikainen, A L ^a   Heath, S C ^a   Hirschfield, G M ^a   Hofman, A ^a   Homuth, G ^a   Hypponen E ^a   Janssen, H L ^a   Johnson, T ^a   Kangas, A J ^a   Kema, I P ^a   Kuhn J P ^a   Lai, S ^a   Lathrop, M ^a   Lerch, 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Couper, D J ^a   Crawford, G ^a   Doney, A ^a   Elliott, K S ^a   Elliott, A L ^a   Erdos, M R ^a   Franklin, C S ^a   Ganser, M ^a   Grarup, N ^a   Green, T ^a   Griffin, S ^a   Groves, C J ^a   Guiducci, C ^a   Hadjadj, S ^a   Hassanali, N ^a   Herder, C ^a   Isomaa, B ^a   Jackson, A U ^a   Johnson, P R ^a   Jorgensen T ^a   Kao, W H ^a   Klopp, N ^a   Kong, A ^a   Kraft, P ^a   Kuusisto, J ^a   Lauritzen, T ^a   Li, M ^a   Lieverse, A ^a   Lindgren, C M ^a   Lyssenko, V ^a   Marre, M ^a   Meitinger, T ^a   Midthjell, K ^a   Morken, M A ^a   Narisu, N ^a   Nilsson, P ^a   Owen, K R ^a   Payne, F ^a   Perry, J R ^a   Petersen, A K ^a   Platou, C ^a   Proenca C ^a   Rathmann, W ^a   William Rayner, N ^a   Robertson, N R ^a   Rocheleau, G ^a   Roden, M ^a   Sampson, M J ^a   Saxena, R ^a   Shields, B ^a   Shrader, P ^a   Sigurdsson, G ^a   Sparso T ^a   Strassburger, K ^a   Stringham, H M ^a   Sun, Q ^a   Swift, A ^a   Thorand, B ^a   Tichet, J ^a   Tuomi, T ^a   van Dam, R M ^a   van 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Turchin, M C ^a   Vandenput, L ^a   Verlaan, D J ^a   Vitart, V ^a   White, C C ^a   Ziegler, A ^a   Almgren, P ^a   Balmforth, A J ^a   Citterio, L ^a   De Grandi, A ^a   Dominiczak, A F ^a   Duan, J ^a   Elosua, R ^a   Eriksson, J G ^a   Freimer, N B ^a   Geus, E J ^a   Glorioso, N ^a   Haiqing, S ^a   Havulinna, A S ^a   Hicks, A A ^a   Hui, J ^a   Igl, W ^a   Jula, A ^a   Kajantie, E ^a   Kilpelainen T O ^a   Koiranen, M ^a   Kolcic, I ^a   Koskinen, S ^a   Kovacs, P ^a   Laitinen, J ^a   Liu, J ^a   Lokki, M L ^a   Marusic, A ^a   Maschio, A ^a   Mulas, A ^a   Pare G ^a   Parker, A N ^a   Petersmann, A ^a   Pichler, I ^a   Ridderstrale M ^a   Rotter, J I ^a   Sambrook, J G ^a   Sanders, A R ^a   Schmidt, C O ^a   Sinisalo, J ^a   Widen, E ^a   Wild, S H ^a   Zagato, L ^a   Zgaga, L ^a   Zitting, P ^a   Alavere, H ^a   McArdle, W L ^a   Nelis, M ^a   Peters, M J ^a   Ripatti, S ^a   van Meurs, J B ^a   Aben, K K ^a   Beckmann, J S ^a   Beilby, J P ^a   Bergmann, S ^a   Cusi, D ^a   Den Heijer, M ^a   Eiriksdottir, G ^a   Gejman, P V ^a   Hamsten, A ^a   Huikuri, H V ^a   Iribarren, C ^a   Kahonen M ^a   Kaprio, J ^a   Kathiresan, S ^a   Kiemeney, L ^a   Kocher, T ^a   Launer, L ^a   Lehtimaki T ^a   Melander, O ^a   Mosley, T H ^a   Musk, A W ^a   Nieminen, M S ^a   Ohlsson, C ^a   Oostra, B A ^a   Palmer, L J ^a   Raitakari, O ^a   Ridker, P M ^a   Rioux, J D ^a   Rissanen, A ^a   Rivolta, C ^a   Schunkert, H ^a   Shuldiner, A R ^a   Siscovick, D S ^a   Stumvoll, M ^a   Tonjes A ^a   van Ommen, G J ^a   Viikari, J ^a   Heath, A C ^a   Province, M A ^a   Kayser, M ^a   Arnold, A M ^a   Chanock, S J ^a   Deloukas, P ^a   Gronberg H ^a   Hall, P ^a   Hengstenberg, C ^a   Hoffman, W ^a   Lathrop, G M ^a   Salomaa, V ^a   Schreiber, S ^a   Wright, A F ^a   Assimes, T L ^a   Cupples, L A ^a   Erdmann, J ^a   Gudnason, V ^a   Hayes, R B ^a   Ouwehand, W H ^a   Quertermous, T ^a   Samani, N J ^a   Haritunians, T ^a   Kaplan, R C ^a   Metspalu, A ^a   North, K E ^a   O'connell, J R ^a   Strachan, D P ^a   Peltonen, L ^a   Visscher, P M ^a   Chatterjee, N ^a   Ingelsson, E ^a   Hirschhorn, J N ^a   Edmondson, A C ^a   Stylianou, I M ^a   Koseki, M ^a   Pirruccello, J P ^a   Johansen, C T ^a   Fouchier, S W ^a   Isaacs, A ^a   Peloso, G M ^a   Barbalic, M ^a   Ricketts, S L ^a   Bis, J C ^a   Orho Melander, M ^a   Guo, X ^a   Cho, Y S ^a   Go, M J ^a   Kim, Y J ^a   Lee, J Y ^a   Park, T ^a   Kim, K ^a   Sim, X ^a   Ong, R T ^a   Croteau Chonka, D C ^a   Lange, L A ^a   Smith, J D ^a   Song, K ^a   Lamina, C ^a   Zee, R Y ^a   Tanaka, T ^a   Silander, K ^a   Scuteri, A ^a   Salomaa, J ^a   Sabatti, C ^a   Rose, L M ^a   Roberts, R ^a   Rieder, M ^a   Psaty, B M ^a   Pedersen, N L ^a   Pattaro, C ^a   Nickerson, D A ^a   McPherson, R ^a   Masson, D ^a   Marroni, F ^a   Magnusson, P K ^a   Lucas, G ^a   Luben, R ^a   Lakatta, E G ^a   Laaksonen, R ^a   Kyvik, K O ^a   Kronenberg, F ^a   Khaw, K T ^a   Janssens, A C ^a   Hovingh, G K ^a   Hastie, N D ^a   Hall, A S ^a   Gonzalez, E ^a   Gieger, N B ^a   Ferrucci, L ^a   Ejebe, K G ^a   Demissie, S ^a   de Faire, U ^a   Chen, Y D ^a   Boekholdt, S M ^a   Bandinelli, S ^a   Ballantyne, C M ^a   Ballantyne, T L ^a   Seielstad, M ^a   Wong, T Y ^a   Tai, E S ^a   Feranil, A B ^a   Kuzawa, C W ^a   Adair, L S ^a   Taylor, H A ^a   Gabriel, S B ^a   Wilson, J G ^a   Krauss, R M ^a   Ordovas, J M ^a   Tall, A R ^a   Hegele, R A ^a   Kastelein, J J ^a   Reilly, M P ^a   Sandhu, M S ^a   Rader, D J ^a   Hernaez, R ^a   Kim, L J ^a   Palmer, C D ^a   Garcia, M ^a   Nalls, M A ^a   Clark, J M ^a   Mitchell, B D ^a   Butler, J L ^a   Tomas, M ^a   Hoffmann, U ^a   Hwang, S J ^a   Massaro, J M ^a   Sahani, D V ^a   Schwartz, S M ^a   Carr, J J ^a   Rice, K ^a   Bochud, M ^a   Johnson, A D ^a   Tobin, M D ^a   Verwoert, G C ^a   Pihur, V ^a   Bragg Gresham, J L ^a   Teumer, A ^a   Sober, S ^a   Parsa, A ^a   Arora, P ^a   Dehghan, A ^a   Zhang, F ^a   Milaneschi, Y ^a   Fava, C ^a   Fox, E R ^a   Kumari, M ^a   Sjogren, M ^a   Vinay, D G ^a   Alexander, M ^a   Tabara, Y ^a   Shaw Hawkins, S ^a   Whincup, P H ^a   Liu, Y ^a   Shi, G ^a   Tayo, B ^a   Nguyen, K D ^a   Matullo, G ^a   Wu, Y ^a   Gaunt, T R ^a   Onland Moret, N C ^a   Org, E ^a   Hardy, R ^a   Dahgam, S ^a   Palmen, J ^a   Braund, P S ^a   Kuznetsova, T ^a   Uiterwaal, C S ^a   Adeyemo, A ^a   Palmas, W ^a   Ludwig, B ^a   Tomaszewski, M ^a   Tzoulaki, I ^a   Palmer, N D ^a   Chang, Y P ^a   Steinle, N I ^a   Grobbee, D E ^a   Arking, D E ^a   Kardia, S L ^a   Morrison, A C ^a   Hernandez, D ^a   Najjar, S ^a   Hadley, D ^a   Connell, J M ^a   Hingorani, A D ^a   Day, I N ^a   Lawlor, D A ^a   Clarke, R ^a   Collins, R ^a   Hopewell, J C ^a   Ongen, H ^a   Dreisbach, A W ^a   Young, J H ^a   Lee, N R ^a   Chen, M H ^a   Olden, M ^a   Bolton, J A ^a   Kottgen, A ^a   Chaturvedi, N R ^a   Islam, M ^a   Jafar, T H ^a   Kulkarni, S R ^a   Bornstein, S R ^a   Grassler, J ^a   Howard, P ^a   Taylor, A ^a   Guarrera, S ^a   Ricceri, F ^a   Emilsson, V ^a   Plump, A ^a   Weder, A B ^a   Hunt, S C ^a   Sun, Y V ^a   Vartiainen, E ^a   Brand, S M ^a   Staessen, J A ^a   Wang, T J ^a   Burton, P R ^a   Artigas, M S ^a   Dong, Y ^a   Wang, X ^a   Zhu, H ^a   Lohman, K K ^a   Rudock, M E ^a   Heckbert, S R ^a   Smith, N L ^a   Wiggins, K L ^a   Doumatey, A ^a   Shriner, D ^a   Veldre, G ^a   Viigimaa, M ^a   Kinra, S ^a   Prabhakaran, D ^a   Tripathy, V ^a   Langefeld, C D ^a   Rosengren, A ^a   Thelle, D S ^a   Corsi, A M ^a   Singleton, A ^a   Forrester, T ^a   Hilton, G ^a   McKenzie, C A ^a   Salako, T ^a   Iwai, N ^a   Kita, Y ^a   Ogihara, T ^a   Ohkubo, T ^a   Okamura, T ^a   Ueshima, H ^a   Umemura, S ^a   Eyheramendy, S ^a   Kim, H L ^a   Hedblad, B ^a   Smith, G D ^a   Wong, A ^a   Stancakova A ^a   Raffel, L J ^a   Yao, J ^a   O'donnell, C ^a   Ikram, M A ^a   Longstreth, W T ^a   Seshadri, S ^a   Shrine, N R ^a   Wain, L V ^a   Cooper, J A ^a   Humphries, S E ^a   Danesh, J ^a   Rasheed, A ^a   Goel, A ^a   Bakker, S J ^a   van Gilst, W H ^a   Janipalli, C S ^a   Mani, K R ^a   Yajnik, C S ^a   Mattace Raso, F U ^a   Demirkan, A ^a   Orru, M ^a   Lyytikainen, L P ^a   Wurz, P ^a   Dorr, M ^a   Kroemer, H K ^a   Volker, U ^a   Volzke, H ^a   Galan, P ^a   Hercberg, S ^a   Zelenika, D ^a   Zhai, G ^a   Meschia, J F ^a   Sharma, P ^a   Terzic, J ^a   Kumar, M J ^a   Denniff, M ^a   Zukowska Szczechowska, E ^a   Wagenknecht, L E ^a   Fowkes, F G ^a   Charchar, F J ^a   Schwarz, P ^a   Rotimi, C ^a   Bots, M L ^a   Brand, E ^a   Talmud, P J ^a   Nyberg, F ^a   Kuh, D ^a   Laan, M ^a   van der Schouw, Y T ^a   Casas, J P ^a   Vineis, P ^a   Ganesh, S K ^a   Cooper, R S ^a   Rao, D C ^a   Morris, R W ^a   Kivimaki, M ^a   Marmot, M G ^a   Miki, T ^a   Saleheen, D ^a   Chandak, G R ^a   Coresh, J ^a   Navis, G ^a   Han, B G ^a   Zhu, X ^a   Meneton, P ^a   Rettig, R ^a   Larson, M G ^a   Chakravarti, A ^a   Newton Cheh, C ^a   Levy, D ^a   Bouatia Naji, N ^a   Rybin, D ^a   Henneman, P ^a   Egan, J M ^a   Lajunen, T ^a   Kanoni, S ^a   Cavalcanti Proenca C ^a   Timpson, N J ^a   Zabena, C ^a   An, P ^a   Elliott, A ^a   Roccasecca, R M ^a   Pattou, F ^a   Sethupathy, P ^a   Ariyurek, Y ^a   Barter, P ^a   Ben Shlomo, Y ^a   Bonnefond, A ^a   Borch Johnsen, K ^a   Bottcher Y ^a   Brunner, E ^a   Crisponi, L ^a   Delplanque, J ^a   Fedson, A C ^a   Fischer Rosinsky, A ^a   Frants, R ^a   Franzosi, M G ^a   Goodarzi, M O ^a   Graessler, J ^a   Grundy, S ^a   Gwilliam, R ^a   Hallmans, G ^a   Hammond, N ^a   Han, X ^a   Hillman, D R ^a   Hung, J ^a   Kaakinen, M ^a   Kesaniemi, Y A ^a   Knight, B ^a   Le Bacquer, O ^a   Lecoeur, C ^a   Mahley, R ^a   Manning, A K ^a   Martinez Larrad M T ^a   McAteer, J B ^a   Melzer, D ^a   Meyre, D ^a   Mukherjee, S ^a   Naitza, S ^a   Neville, M J ^a   Orru M ^a   Pakyz, R ^a   Paolisso, G ^a   Pearson, D ^a   Pfeiffer, A F ^a   Posthuma, D ^a   Potter, S C ^a   Rolandsson, O ^a   Sandbaek, A ^a   Sayer, A A ^a   Scheet, P ^a   Sharp, S J ^a   Sigurethsson, G ^a   Silveira, A ^a   Simpson, L ^a   Syddall, H ^a   Syvanen A C ^a   van Dijk, K W ^a   Varma, D ^a   Visvikis Siest, S ^a   Vogelzangs, N ^a   Wagner, P J ^a   Walley, A ^a   Ward, K L ^a   Yarnell, J W ^a   Zethelius, B ^a   Nathan, D M ^a   Williams, G H ^a   Spranger, J ^a   Karpe, F ^a   Cooper, C ^a   Dedoussis, G V ^a   Serrano Rios M ^a   Lind, L ^a   Franks, P W ^a   Ebrahim, S ^a   Buchanan, T A ^a   Valle, T T ^a   Cao, A ^a   Barroso, ^a   more..

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; GLUCOSE; GLUTATHIONE; GLYCOPROTEIN; LIPID; LIVER ENZYME;

ARTICLE; BIOSYNTHESIS; CARBOHYDRATE METABOLISM; FUNCTIONAL GENOMICS; GENE EXPRESSION; GENE LOCUS; GENETIC ASSOCIATION; GLUCOSE METABOLISM; HUMAN; IMMUNITY; INFLAMMATION; LIPID METABOLISM; LIVER FUNCTION; LIVER INJURY; MAJOR CLINICAL STUDY; METABOLOMICS; PHENOTYPE; PLASMA; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 80055024880     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.970     Document Type: Article

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