Kcnn4 is a regulator of macrophage multinucleation in bone homeostasis and inflammatory disease

Cell Reports

Volumn 8, Issue 4, 2014, Pages 1210-1224

  Kang, Heeseog ^a   Kerloc'h, Audrey ^b   Rotival, Maxime ^b   Xu, Xiaoqing ^a   Zhang, Qing ^a   D'Souza, Zelpha ^b   Kim, Michael ^a   Scholz, Jodi Carlson ^a   Ko, Jeong Hun ^b   Srivastava, Prashant K ^b   Genzen, Jonathan R ^c   Cui, Weiguo ^d   Aitman, Timothy J ^b   Game, Laurence ^b   Melvin, James E ^e   Hanidu, Adedayo ^f   Dimock, Janice ^f   Zheng, Jie ^f   Souza, Donald ^f   Behera, Aruna K ^f   Nabozny, Gerald ^f   Cook, H Terence ^b   Bassett, J H Duncan ^b   Williams, Graham R ^b   Li, Jun ^f   Vignery, Agnès ^a   Petretto, Enrico ^b   Behmoaras, Jacques ^b   more..

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c ARUP LABORATORIES   (United States)

^d BLOOD RESEARCH INSTITUTE   (United States)

^e NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^f BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; BONE EROSION; BONE HOMEOSTASIS; BONE MASS; BONE TURNOVER; CALCIUM SIGNALING; CHRONIC INFLAMMATION; CONTROLLED STUDY; DISEASE SEVERITY; GENE; GENE DELETION; GENE FUSION; GENE INACTIVATION; GENE REGULATORY NETWORK; GENETIC REGULATION; GIANT CELL; HOMEOSTASIS; HUMAN; IMMUNE COMPLEX NEPHRITIS; INFLAMMATORY DISEASE; KCNN4 GENE; MACROPHAGE; MACROPHAGE FUNCTION; MACROPHAGE MULTINUCLEATION; MMNET GENE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; RAT; REGULATOR GENE; RODENT; TREM2 GENE; ANIMAL; BONE; CELL CULTURE; CELL NUCLEUS; GLOMERULONEPHRITIS; IMMUNOLOGY; KNOCKOUT MOUSE; LEWIS RAT; METABOLISM; PATHOLOGY; PHYSIOLOGY; WISTAR KYOTO RAT; ANIMAL CELL; BONE METABOLISM; EXPERIMENTAL GLOMERULONEPHRITIS; FEMALE; HUMAN CELL; MALE; MOUSE; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

RATTUS; RODENTIA;

IMMUNOGLOBULIN RECEPTOR; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; KCNN4 PROTEIN, RAT; CALCIUM ION; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNN4; UNCLASSIFIED DRUG;

ANIMALS; ARTHRITIS; BONE AND BONES; BONE RESORPTION; CALCIUM SIGNALING; CELL NUCLEUS; CELLS, CULTURED; GENE REGULATORY NETWORKS; GLOMERULONEPHRITIS; HOMEOSTASIS; HUMANS; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MACROPHAGES; MICE, KNOCKOUT; RATS, INBRED LEW; RATS, INBRED WKY; RECEPTORS, IMMUNOLOGIC;

EID: 84908355965     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.07.032     Document Type: Article

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