-
1
-
-
34447132814
-
Skeletal remodeling in health and disease
-
ZAIDI, M. 2007. Skeletal remodeling in health and disease. Nat. Med. 13: 791-801.
-
(2007)
Nat. Med
, vol.13
, pp. 791-801
-
-
ZAIDI, M.1
-
2
-
-
0043267732
-
Genetic regulation of osteoclast development and function
-
TEITELBAUM, S.L. & F.P. ROSS. 2003. Genetic regulation of osteoclast development and function. Nat. Rev. Genet. 4: 638-649.
-
(2003)
Nat. Rev. Genet
, vol.4
, pp. 638-649
-
-
TEITELBAUM, S.L.1
ROSS, F.P.2
-
3
-
-
0037673945
-
Osteoclast differentiation and activation
-
BOYLE, W.J., W.S. SIMONET & D.L. LACEY. 2003. Osteoclast differentiation and activation. Nature 423: 337-342.
-
(2003)
Nature
, vol.423
, pp. 337-342
-
-
BOYLE, W.J.1
SIMONET, W.S.2
LACEY, D.L.3
-
4
-
-
0033304730
-
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
-
SUDA, T. et al. 1999. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocrine Rev. 20: 345-357.
-
(1999)
Endocrine Rev
, vol.20
, pp. 345-357
-
-
SUDA, T.1
-
5
-
-
33947583822
-
Osteoimmunology: Shared mechanisms and crosstalk between the immune and bone systems
-
TAKAYANAGI, H. 2007. Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. Nat. Rev. Immunol. 7: 292-304.
-
(2007)
Nat. Rev. Immunol
, vol.7
, pp. 292-304
-
-
TAKAYANAGI, H.1
-
6
-
-
0030714605
-
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function
-
ANDERSON, D.M. et al. 1997. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 390: 175-179.
-
(1997)
Nature
, vol.390
, pp. 175-179
-
-
ANDERSON, D.M.1
-
7
-
-
14444272043
-
TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells
-
WONG, B.R. et al. 1997. TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells. J. Biol. Chem. 272: 25190-25194.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 25190-25194
-
-
WONG, B.R.1
-
8
-
-
0032584208
-
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
-
YASUDA, H. et al. 1998. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc. Natl. Acad. Sci. USA 95: 3597-3602.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 3597-3602
-
-
YASUDA, H.1
-
9
-
-
0032540319
-
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
-
LACEY, D.L. et al. 1998. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93: 165-176.
-
(1998)
Cell
, vol.93
, pp. 165-176
-
-
LACEY, D.L.1
-
10
-
-
0033611467
-
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
-
KONG, Y.Y. et al. 1999. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 397: 315-323.
-
(1999)
Nature
, vol.397
, pp. 315-323
-
-
KONG, Y.Y.1
-
11
-
-
0033568341
-
RANK is essential for osteoclast and lymph node development
-
DOUGALL, W.C. et al. 1999. RANK is essential for osteoclast and lymph node development. Genes Dev. 13: 2412-2424.
-
(1999)
Genes Dev
, vol.13
, pp. 2412-2424
-
-
DOUGALL, W.C.1
-
12
-
-
0032079445
-
Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification
-
BUCAY, N. et al. 1998. Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification. Genes Dev. 12: 1260-1268.
-
(1998)
Genes Dev
, vol.12
, pp. 1260-1268
-
-
BUCAY, N.1
-
13
-
-
15444381042
-
RANK-mediated amplification of TRAF6 signaling leads to NFATc1 induction during osteoclastogenesis
-
GOHDA, J. et al. 2005. RANK-mediated amplification of TRAF6 signaling leads to NFATc1 induction during osteoclastogenesis. EMBO J. 24: 790-799.
-
(2005)
EMBO J
, vol.24
, pp. 790-799
-
-
GOHDA, J.1
-
14
-
-
6544270833
-
Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice
-
NAITO, A. et al. 1999. Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice. Genes Cells 4: 353-362.
-
(1999)
Genes Cells
, vol.4
, pp. 353-362
-
-
NAITO, A.1
-
15
-
-
15444357762
-
Requirement for NF-κB in osteoclast and B-cell development
-
FRANZOSO, G. et al. 1997. Requirement for NF-κB in osteoclast and B-cell development. Genes Dev. 11: 3482-3496.
-
(1997)
Genes Dev
, vol.11
, pp. 3482-3496
-
-
FRANZOSO, G.1
-
16
-
-
0030715563
-
Osteopetrosis in mice lacking NF-κB1 and NF-κB2
-
IOTSOVA, V. et al. 1997. Osteopetrosis in mice lacking NF-κB1 and NF-κB2. Nat. Med. 3: 1285-1289.
-
(1997)
Nat. Med
, vol.3
, pp. 1285-1289
-
-
IOTSOVA, V.1
-
17
-
-
0028173214
-
c-Fos: A key regulator of osteoclast-macrophage lineage determination and bone remodeling
-
GRIGORIADIS, A.E. et al. 1994. c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling. Science 266: 443-448.
-
(1994)
Science
, vol.266
, pp. 443-448
-
-
GRIGORIADIS, A.E.1
-
18
-
-
18744366041
-
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling for terminal differentiation of osteoclasts
-
TAKAYANAGI, H. et al. 2002. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling for terminal differentiation of osteoclasts. Dev. Cell 3: 889-901.
-
(2002)
Dev. Cell
, vol.3
, pp. 889-901
-
-
TAKAYANAGI, H.1
-
19
-
-
0037174944
-
Large scale gene expression analysis of osteoclastogenesis in vitro and elucidation of NFAT2 as a key regulator
-
ISHIDA, N. et al. 2002. Large scale gene expression analysis of osteoclastogenesis in vitro and elucidation of NFAT2 as a key regulator. J. Biol. Chem. 277: 41147-41156.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 41147-41156
-
-
ISHIDA, N.1
-
20
-
-
4344697340
-
Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation
-
IKEDA, F. et al. 2004. Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation. J. Clin. Invest. 114: 475-484.
-
(2004)
J. Clin. Invest
, vol.114
, pp. 475-484
-
-
IKEDA, F.1
-
21
-
-
2942731511
-
Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos
-
MATSUO, K. et al. 2004. Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos. J. Biol. Chem. 279: 26475-26480.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 26475-26480
-
-
MATSUO, K.1
-
22
-
-
0032510493
-
Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum
-
DE LA POMPA, J.L. et al. 1998. Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum. Nature 392: 182-186.
-
(1998)
Nature
, vol.392
, pp. 182-186
-
-
DE LA POMPA, J.L.1
-
23
-
-
0032510581
-
The transcription factor NF-ATc is essential for cardiac valve formation
-
RANGER, A.M. et al. 1998. The transcription factor NF-ATc is essential for cardiac valve formation. Nature 392: 186-190.
-
(1998)
Nature
, vol.392
, pp. 186-190
-
-
RANGER, A.M.1
-
24
-
-
27744432009
-
Autoamplification of NFATc1 expression determines its essential role in bone homeostasis
-
ASAGIRI, M. et al. 2005. Autoamplification of NFATc1 expression determines its essential role in bone homeostasis. J. Exp. Med. 202: 1261-1269.
-
(2005)
J. Exp. Med
, vol.202
, pp. 1261-1269
-
-
ASAGIRI, M.1
-
25
-
-
33646890016
-
Calcineurin/NFAT signaling in osteoblasts regulates bone mass
-
WINSLOW, M.M. et al. 2006. Calcineurin/NFAT signaling in osteoblasts regulates bone mass. Dev. Cell 10: 771-782.
-
(2006)
Dev. Cell
, vol.10
, pp. 771-782
-
-
WINSLOW, M.M.1
-
26
-
-
0037148508
-
A novel member of the leukocyte receptor complex regulates osteoclast differentiation
-
KIM, N., M. TAKAMI, J. RHO, et al. 2002. A novel member of the leukocyte receptor complex regulates osteoclast differentiation. J. Exp. Med. 195: 201-209.
-
(2002)
J. Exp. Med
, vol.195
, pp. 201-209
-
-
KIM, N.1
TAKAMI, M.2
RHO, J.3
-
27
-
-
11144354330
-
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis
-
KOGA, T. et al. 2004. Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis. Nature 428: 758-763.
-
(2004)
Nature
, vol.428
, pp. 758-763
-
-
KOGA, T.1
-
28
-
-
11144355389
-
The immunomodulatory adapter proteins DAP12 and Fc receptor γ-chain (FcRγ) regulate development of functional osteoclasts through the Syk tyrosine kinase
-
MOCSAI, A. et al. 2004. The immunomodulatory adapter proteins DAP12 and Fc receptor γ-chain (FcRγ) regulate development of functional osteoclasts through the Syk tyrosine kinase. Proc. Natl. Acad. Sci. USA 101: 6158-6163.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 6158-6163
-
-
MOCSAI, A.1
-
29
-
-
33750597150
-
PLCγ2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2
-
MAO, D., H. EPPLE, B. UTHGENANNT, et al. 2006. PLCγ2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2. J. Clin. Invest. 116: 2869-2879.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 2869-2879
-
-
MAO, D.1
EPPLE, H.2
UTHGENANNT, B.3
-
30
-
-
33845539490
-
Regulation of osteoclast differentiation and function by the CaMK-CREB pathway
-
SATO, K. et al. 2006. Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. Nat. Med. 12: 1410-1416.
-
(2006)
Nat. Med
, vol.12
, pp. 1410-1416
-
-
SATO, K.1
-
31
-
-
8544267975
-
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1
-
MATSUMOTO, M. et al. 2004. Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1. J. Biol. Chem. 279: 45969-45979.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 45969-45979
-
-
MATSUMOTO, M.1
-
32
-
-
33646068740
-
NFATc1 regulation of the human β3 integrin promoter in osteoclast differentiation
-
CROTTI, T.N. et al. 2006. NFATc1 regulation of the human β3 integrin promoter in osteoclast differentiation. Gene 372: 92-102.
-
(2006)
Gene
, vol.372
, pp. 92-102
-
-
CROTTI, T.N.1
-
33
-
-
27444437574
-
Nuclear factor of activated T cells c1 induces osteoclastassociated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesis
-
KIM, K. et al. 2005. Nuclear factor of activated T cells c1 induces osteoclastassociated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesis. J. Biol. Chem. 280: 35209-35216.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 35209-35216
-
-
KIM, K.1
-
34
-
-
25444444351
-
Contribution of nuclear factor of activated T cells c1 to the transcriptional control of immunoreceptor osteoclast-associated receptor but not triggering receptor expressed by myeloid cells-2 during osteoclastogenesis
-
KIM, Y. et al. 2005. Contribution of nuclear factor of activated T cells c1 to the transcriptional control of immunoreceptor osteoclast-associated receptor but not triggering receptor expressed by myeloid cells-2 during osteoclastogenesis. J. Biol. Chem. 280: 32905-32913.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 32905-32913
-
-
KIM, Y.1
-
35
-
-
23744459835
-
DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells
-
YAGI, M. et al. 2005. DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells. J. Exp. Med. 202: 345-351.
-
(2005)
J. Exp. Med
, vol.202
, pp. 345-351
-
-
YAGI, M.1
-
36
-
-
33845537394
-
v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation
-
LEE, S.H. et al. 2006. v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation. Nat. Med. 12: 1403-1409.
-
(2006)
Nat. Med
, vol.12
, pp. 1403-1409
-
-
LEE, S.H.1
|