-
1
-
-
84879369738
-
Commensal bacteria at the interface of host metabolism and the immune system
-
J.R. Brestoff, and D. Artis Commensal bacteria at the interface of host metabolism and the immune system Nat. Immunol. 14 2013 676 684
-
(2013)
Nat. Immunol.
, vol.14
, pp. 676-684
-
-
Brestoff, J.R.1
Artis, D.2
-
2
-
-
79959271087
-
Intestinal homeostasis and its breakdown in inflammatory bowel disease
-
K.J. Maloy, and F. Powrie Intestinal homeostasis and its breakdown in inflammatory bowel disease Nature 474 2011 298 306
-
(2011)
Nature
, vol.474
, pp. 298-306
-
-
Maloy, K.J.1
Powrie, F.2
-
3
-
-
0025572276
-
OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: Prevention by the OX-221ow subset
-
F. Powrie, and D. Mason OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-221ow subset J. Exp. Med. 172 1990 1701 1708
-
(1990)
J. Exp. Med.
, vol.172
, pp. 1701-1708
-
-
Powrie, F.1
Mason, D.2
-
4
-
-
74049164847
-
Regulatory T cells exert checks and balances on self tolerance and autoimmunity
-
K. Wing, and S. Sakaguchi Regulatory T cells exert checks and balances on self tolerance and autoimmunity Nat. Immunol. 11 2010 7 13
-
(2010)
Nat. Immunol.
, vol.11
, pp. 7-13
-
-
Wing, K.1
Sakaguchi, S.2
-
6
-
-
41949097030
-
The biology of interleukin-2
-
T.R. Malek The biology of interleukin-2 Annu. Rev. Immunol. 26 2008 453 479
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 453-479
-
-
Malek, T.R.1
-
7
-
-
0031906218
-
Lymphoid hyperplasia, autoimmunity, and compromised intestinal intraepithelial lymphocyte development in colitis-free gnotobiotic IL-2-deficientmice
-
N.V. Contractor, H. Bassiri, T. Reya, A.Y. Park, D.C. Baumgart, M.A. Wasik, S.G. Emerson, and S.R. Carding Lymphoid hyperplasia, autoimmunity, and compromised intestinal intraepithelial lymphocyte development in colitis-free gnotobiotic IL-2-deficientmice J. Immunol. 160 1998 385 394
-
(1998)
J. Immunol.
, vol.160
, pp. 385-394
-
-
Contractor, N.V.1
Bassiri, H.2
Reya, T.3
Park, A.Y.4
Baumgart, D.C.5
Wasik, M.A.6
Emerson, S.G.7
Carding, S.R.8
-
8
-
-
0033000343
-
IL-2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammation
-
M. Schultz, S.L. Tonkonogy, R.K. Sellon, C. Veltkamp, V.L. Godfrey, J. Kwon, W.B. Grenther, E. Balish, I. Horak, and R.B. Sartor IL-2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammation Am. J. Physiol. 276 1999 461 472
-
(1999)
Am. J. Physiol.
, vol.276
, pp. 461-472
-
-
Schultz, M.1
Tonkonogy, S.L.2
Sellon, R.K.3
Veltkamp, C.4
Godfrey, V.L.5
Kwon, J.6
Grenther, W.B.7
Balish, E.8
Horak, I.9
Sartor, R.B.10
-
9
-
-
0027369395
-
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
-
B. Sadlack, H. Merz, H. Schorle, A. Schimpl, A.C. Feller, and I. Horak Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene Cell 75 1993 253 261
-
(1993)
Cell
, vol.75
, pp. 253-261
-
-
Sadlack, B.1
Merz, H.2
Schorle, H.3
Schimpl, A.4
Feller, A.C.5
Horak, I.6
-
10
-
-
78149310029
-
A critical role for regulatory T cell-mediated control of inflammation in the absence of commensal microbiota
-
T. Chinen, P.Y. Volchkov, A.V. Chervonsky, and A.Y. Rudensky A critical role for regulatory T cell-mediated control of inflammation in the absence of commensal microbiota J. Exp. Med. 207 2010 2323 2330
-
(2010)
J. Exp. Med.
, vol.207
, pp. 2323-2330
-
-
Chinen, T.1
Volchkov, P.Y.2
Chervonsky, A.V.3
Rudensky, A.Y.4
-
11
-
-
84901065053
-
The epigenetic regulator Uhrfl facilitates the proliferation and maturation of colonic regulatory T cells
-
Y. Obata, Y. Furusawa, T.A. Endo, J. Sharif, D. Takahashi, K. Atarashi, M. Nakayama, S. Onawa, Y. Fujimura, M. Takahashi, T. Ikawa, T. Otsubo, Y.I. Kawamura, T. Dohi, S. Tajima, H. Masumoto, O. Ohara, K. Honda, S. Hori, H. Ohno, H. Koseki, and K. Hase The epigenetic regulator Uhrfl facilitates the proliferation and maturation of colonic regulatory T cells Nat. Immunol. 15 2014 571 579
-
(2014)
Nat. Immunol.
, vol.15
, pp. 571-579
-
-
Obata, Y.1
Furusawa, Y.2
Endo, T.A.3
Sharif, J.4
Takahashi, D.5
Atarashi, K.6
Nakayama, M.7
Onawa, S.8
Fujimura, Y.9
Takahashi, M.10
Ikawa, T.11
Otsubo, T.12
Kawamura, Y.I.13
Dohi, T.14
Tajima, S.15
Masumoto, H.16
Ohara, O.17
Honda, K.18
Hori, S.19
Ohno, H.20
Koseki, H.21
Hase, K.22
more..
-
12
-
-
0038783387
-
Colitogenic Th1 cells are present in the antigen-experienced T cell pool in normal mice: Control by CD4+ regulatory T cells and IL-10
-
C. Asseman, S. Read, and F. Powrie Colitogenic Th1 cells are present in the antigen-experienced T cell pool in normal mice: control by CD4+ regulatory T cells and IL-10 J. Immunol. 171 2003 971 978
-
(2003)
J. Immunol.
, vol.171
, pp. 971-978
-
-
Asseman, C.1
Read, S.2
Powrie, F.3
-
13
-
-
84897939526
-
T-cell selection and intestinal homeostasis
-
T.L. Ai, B.D. Solomon, and C.S. Hsieh T-cell selection and intestinal homeostasis Immunol. Rev. 259 2014 60 74
-
(2014)
Immunol. Rev.
, vol.259
, pp. 60-74
-
-
Ai, T.L.1
Solomon, B.D.2
Hsieh, C.S.3
-
14
-
-
84883679673
-
Peripherally induced tregs - Role in immune homeostasis and autoimmunity
-
M. Yadav, S. Stephan, and J.A. Bluestone Peripherally induced tregs - role in immune homeostasis and autoimmunity Fron. Immunol. 4 2013 232
-
(2013)
Fron. Immunol.
, vol.4
, pp. 232
-
-
Yadav, M.1
Stephan, S.2
Bluestone, J.A.3
-
15
-
-
84859390119
-
Induced CD4+Foxp3+ regulatory T cells in immune tolerance
-
A.M. Bilate, and J.J. Lafaille Induced CD4+Foxp3+ regulatory T cells in immune tolerance Annu. Rev. Immunol. 30 2012 733 758
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 733-758
-
-
Bilate, A.M.1
Lafaille, J.J.2
-
16
-
-
82755198003
-
Regulatory T cell lineage commitment in the thymus
-
L. Klein, and K. Jovanovic Regulatory T cell lineage commitment in the thymus Semin. Immunol. 23 2011 401 409
-
(2011)
Semin. Immunol.
, vol.23
, pp. 401-409
-
-
Klein, L.1
Jovanovic, K.2
-
17
-
-
84862814979
-
Selection of regulatory T cells in the thymus
-
C.S. Hsieh, H.M. Lee, and C.W. Lio Selection of regulatory T cells in the thymus Nat. Rev. Immunol. 12 2012 157 167
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 157-167
-
-
Hsieh, C.S.1
Lee, H.M.2
Lio, C.W.3
-
18
-
-
34547757390
-
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 Treg cells via retinoic acid
-
C.M. Sun, J.A. Hall, R.B. Blank, N. Bouladoux, M. Oukka, J.R. Mora, and Y. Belkaid Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 Treg cells via retinoic acid J. Exp. Med. 204 2007 1775 1785
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1775-1785
-
-
Sun, C.M.1
Hall, J.A.2
Blank, R.B.3
Bouladoux, N.4
Oukka, M.5
Mora, J.R.6
Belkaid, Y.7
-
19
-
-
77951638740
-
Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells
-
A.M. Thornton, P.E. Korty, D.Q. Tran, E.A. Wohlfert, P.E. Murray, Y. Belkaid, and E.M. Shevach Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells J. Immunol. 184 2010 3433 3441
-
(2010)
J. Immunol.
, vol.184
, pp. 3433-3441
-
-
Thornton, A.M.1
Korty, P.E.2
Tran, D.Q.3
Wohlfert, E.A.4
Murray, P.E.5
Belkaid, Y.6
Shevach, E.M.7
-
20
-
-
84867899425
-
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells
-
SI
-
J.M. Weiss, A.M. Bilate, M. Gobert, Y. Ding, M.A. Curotto de Lafaille, C.N. Parkhurst, H. Xiong, J. Dolpady, A.B. Frey, M.G. Ruocco, Y. Yang, S. Floess, J. Huehn, S. Oh, M.O. Li, R.E. Niec, A.Y. Rudensky, M.L. Dustin, D.R. Littman, and J.J. Lafaille Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells J. Exp. Med. 209 2012 1723 1742 SI
-
(2012)
J. Exp. Med.
, vol.209
, pp. 1723-1742
-
-
Weiss, J.M.1
Bilate, A.M.2
Gobert, M.3
Ding, Y.4
Curotto De Lafaille, M.A.5
Parkhurst, C.N.6
Xiong, H.7
Dolpady, J.8
Frey, A.B.9
Ruocco, M.G.10
Yang, Y.11
Floess, S.12
Huehn, J.13
Oh, S.14
Li, M.O.15
Niec, R.E.16
Rudensky, A.Y.17
Dustin, M.L.18
Littman, D.R.19
Lafaille, J.J.20
more..
-
21
-
-
85027947787
-
Induction of colonic regulatory T cells by indigenous Clostridium species
-
K. Atarashi, T. Tanoue, T. Shima, A. Imaoka, T. Kuwahara, Y. Momose, G. Cheng, S. Yamasaki, T. Saito, Y. Ohba, T. Taniguchi, K. Takeda, S. Hori, I.I. Ivanov, Y. Umesaki, K. Itoh, and K. Honda Induction of colonic regulatory T cells by indigenous Clostridium species Science 331 2011 337 341
-
(2011)
Science
, vol.331
, pp. 337-341
-
-
Atarashi, K.1
Tanoue, T.2
Shima, T.3
Imaoka, A.4
Kuwahara, T.5
Momose, Y.6
Cheng, G.7
Yamasaki, S.8
Saito, T.9
Ohba, Y.10
Taniguchi, T.11
Takeda, K.12
Hori, S.13
Ivanov, I.I.14
Umesaki, Y.15
Itoh, K.16
Honda, K.17
-
22
-
-
80054020840
-
Peripheral education of the immune system by colonic commensal microbiota
-
S.K. Lathrop, S.M. Bloom, S.M. Rao, K. Nutsch, C.W. Lio, N. Santacruz, D.A. Peterson, T.S. Stappenbeck, and C.S. Hsieh Peripheral education of the immune system by colonic commensal microbiota Nature 478 2011 250 254
-
(2011)
Nature
, vol.478
, pp. 250-254
-
-
Lathrop, S.K.1
Bloom, S.M.2
Rao, S.M.3
Nutsch, K.4
Lio, C.W.5
Santacruz, N.6
Peterson, D.A.7
Stappenbeck, T.S.8
Hsieh, C.S.9
-
23
-
-
79960453738
-
A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity
-
D. Haribhai, J.B. Williams, S. Jia, D. Nickerson, E.G. Schmitt, B. Edwards, J. Ziegelbauer, M. Yassai, S.H. Li, L.M. Relland, P.M. Wise, A. Chen, Y.Q. Zheng, P.M. Simpson, J. Gorski, N.H. Salzman, M.J. Hessner, T.A. Chatila, and C.B. Williams A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity Immunity 35 2011 109 122
-
(2011)
Immunity
, vol.35
, pp. 109-122
-
-
Haribhai, D.1
Williams, J.B.2
Jia, S.3
Nickerson, D.4
Schmitt, E.G.5
Edwards, B.6
Ziegelbauer, J.7
Yassai, M.8
Li, S.H.9
Relland, L.M.10
Wise, P.M.11
Chen, A.12
Zheng, Y.Q.13
Simpson, P.M.14
Gorski, J.15
Salzman, N.H.16
Hessner, M.J.17
Chatila, T.A.18
Williams, C.B.19
-
24
-
-
84862777225
-
Extrathymically generated regulatory T cells control mucosal TH2 inflammation
-
S.Z. Josefowicz, R.E. Niec, H.Y. Kim, P. Treuting, T. Chinen, Y. Zheng, D.T. Umetsu, and A.Y. Rudensky Extrathymically generated regulatory T cells control mucosal TH2 inflammation Nature 482 2012 395 399
-
(2012)
Nature
, vol.482
, pp. 395-399
-
-
Josefowicz, S.Z.1
Niec, R.E.2
Kim, H.Y.3
Treuting, P.4
Chinen, T.5
Zheng, Y.6
Umetsu, D.T.7
Rudensky, A.Y.8
-
25
-
-
62649165369
-
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses
-
Y. Zheng, A. Chaudhry, A. Kas, P. deRoos, J.M. Kim, T.T. Chu, L. Corcoran, P. Treuting, U. Klein, and A.Y. Rudensky Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses Nature 458 2009 351 356
-
(2009)
Nature
, vol.458
, pp. 351-356
-
-
Zheng, Y.1
Chaudhry, A.2
Kas, A.3
Deroos, P.4
Kim, J.M.5
Chu, T.T.6
Corcoran, L.7
Treuting, P.8
Klein, U.9
Rudensky, A.Y.10
-
26
-
-
84856567623
-
Expression of Helios in peripherally induced Foxp3+ regulatory T cells
-
R.A. Gottschalk, E. Corse, and J.P. Allison Expression of Helios in peripherally induced Foxp3+ regulatory T cells J. Immunol. 188 2012 976 980
-
(2012)
J. Immunol.
, vol.188
, pp. 976-980
-
-
Gottschalk, R.A.1
Corse, E.2
Allison, J.P.3
-
27
-
-
80052287274
-
Helios expression is a marker of T cell activation and proliferation
-
T. Akimova, U.H. Beier, L. Wang, M.H. Levine, and W.W. Hancock Helios expression is a marker of T cell activation and proliferation PLoS One 6 2011 e24226
-
(2011)
PLoS One
, vol.6
, pp. 24226
-
-
Akimova, T.1
Beier, U.H.2
Wang, L.3
Levine, M.H.4
Hancock, W.W.5
-
28
-
-
84877742439
-
Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota
-
A. Cebula, M. Seweryn, G.A. Rempala, S.S. Pabla, R.A. McIndoe, T.L. Denning, L. Bry, P. Kraj, P. Kisielow, and L. Ignatowicz Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota Nature 497 2013 258 262
-
(2013)
Nature
, vol.497
, pp. 258-262
-
-
Cebula, A.1
Seweryn, M.2
Rempala, G.A.3
Pabla, S.S.4
McIndoe, R.A.5
Denning, T.L.6
Bry, L.7
Kraj, P.8
Kisielow, P.9
Ignatowicz, L.10
-
29
-
-
84881477044
-
Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota
-
K. Atarashi, T. Tanoue, K. Oshima, W. Suda, Y. Nagano, H. Nishikawa, S. Fukuda, T. Saito, S. Narushima, K. Hase, S. Kim, J.V. Fritz, P. Wilmes, S. Ueha, K. Matsushima, H. Ohno, B. Olle, S. Sakaguchi, T. Taniguchi, H. Morita, M. Hattori, and K. Honda Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota Nature 500 2013 232 236
-
(2013)
Nature
, vol.500
, pp. 232-236
-
-
Atarashi, K.1
Tanoue, T.2
Oshima, K.3
Suda, W.4
Nagano, Y.5
Nishikawa, H.6
Fukuda, S.7
Saito, T.8
Narushima, S.9
Hase, K.10
Kim, S.11
Fritz, J.V.12
Wilmes, P.13
Ueha, S.14
Matsushima, K.15
Ohno, H.16
Olle, B.17
Sakaguchi, S.18
Taniguchi, T.19
Morita, H.20
Hattori, M.21
Honda, K.22
more..
-
30
-
-
79956315886
-
Intestinal bacterial colonization induces mutualistic regulatory T cell responses
-
M.B. Geuking, J. Cahenzli, M.A. Lawson, D.C. Ng, E. Slack, S. Hapfelmeier, K.D. McCoy, and A.J. Macpherson Intestinal bacterial colonization induces mutualistic regulatory T cell responses Immunity 34 2011 794 806
-
(2011)
Immunity
, vol.34
, pp. 794-806
-
-
Geuking, M.B.1
Cahenzli, J.2
Lawson, M.A.3
Ng, D.C.4
Slack, E.5
Hapfelmeier, S.6
McCoy, K.D.7
Macpherson, A.J.8
-
31
-
-
74249088146
-
Gut commensal Lactobacillus reuteri 100-23 stimulates an immunoregulatory response
-
M. Livingston, D. Loach, M. Wilson, G.W. Tannock, and M. Baird Gut commensal Lactobacillus reuteri 100-23 stimulates an immunoregulatory response Immunol. Cell Biol. 88 2010 99 102
-
(2010)
Immunol. Cell Biol.
, vol.88
, pp. 99-102
-
-
Livingston, M.1
Loach, D.2
Wilson, M.3
Tannock, G.W.4
Baird, M.5
-
32
-
-
34447503805
-
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
-
D. Mucida, Y. Park, G. Kim, O. Turovskaya, I. Scott, M. Kronenberg, and H. Cheroutre Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid Science 317 2007 256 260
-
(2007)
Science
, vol.317
, pp. 256-260
-
-
Mucida, D.1
Park, Y.2
Kim, G.3
Turovskaya, O.4
Scott, I.5
Kronenberg, M.6
Cheroutre, H.7
-
33
-
-
34547769253
-
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation
-
M.J. Benson, K. Pino-Lagos, M. Rosemblatt, and R.J. Noelle All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation J. Exp. Med. 204 2007 1765 1774
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1765-1774
-
-
Benson, M.J.1
Pino-Lagos, K.2
Rosemblatt, M.3
Noelle, R.J.4
-
34
-
-
55549084247
-
Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells
-
J.A. Hill, J.A. Hall, C.M. Sun, Q. Cai, N. Ghyselinck, P. Chambon, Y. Belkaid, D. Mathis, and C. Benoist Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells Immunity 29 2008 758 770
-
(2008)
Immunity
, vol.29
, pp. 758-770
-
-
Hill, J.A.1
Hall, J.A.2
Sun, C.M.3
Cai, Q.4
Ghyselinck, N.5
Chambon, P.6
Belkaid, Y.7
Mathis, D.8
Benoist, C.9
-
35
-
-
70350478405
-
Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines
-
J. Nolting, C. Daniel, S. Reuter, C. Stuelten, P. Li, H. Sucov, B.G. Kim, J.J. Letterio, K. Kretschmer, H.J. Kim, and H. von Boehmer Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines J. Exp. Med. 206 2009 2131 2139
-
(2009)
J. Exp. Med.
, vol.206
, pp. 2131-2139
-
-
Nolting, J.1
Daniel, C.2
Reuter, S.3
Stuelten, C.4
Li, P.5
Sucov, H.6
Kim, B.G.7
Letterio, J.J.8
Kretschmer, K.9
Kim, H.J.10
Von Boehmer, H.11
-
36
-
-
34547788180
-
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
-
J.L. Coombes, K.R. Siddiqui, C.V. Arancibia-Carcamo, J. Hall, C.M. Sun, Y. Belkaid, and F. Powrie A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism J. Exp. Med. 204 2007 1757 1764
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1757-1764
-
-
Coombes, J.L.1
Siddiqui, K.R.2
Arancibia-Carcamo, C.V.3
Hall, J.4
Sun, C.M.5
Belkaid, Y.6
Powrie, F.7
-
37
-
-
77955634800
-
Activation of beta-catenin in dendritic cells regulates immunity versus tolerance in the intestine
-
S. Manicassamy, B. Reizis, R. Ravindran, H. Nakaya, R.M. Salazar-Gonzalez, Y.C. Wang, and B. Pulendran Activation of beta-catenin in dendritic cells regulates immunity versus tolerance in the intestine Science 329 2010 849 853
-
(2010)
Science
, vol.329
, pp. 849-853
-
-
Manicassamy, S.1
Reizis, B.2
Ravindran, R.3
Nakaya, H.4
Salazar-Gonzalez, R.M.5
Wang, Y.C.6
Pulendran, B.7
-
38
-
-
84886280379
-
Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals
-
M. Shan, M. Gentile, J.R. Yeiser, A.C. Walland, V.U. Bornstein, K. Chen, B. He, L. Cassis, A. Bigas, M. Cols, L. Comerma, B. Huang, J.M. Blander, H. Xiong, L. Mayer, C. Berin, L.H. Augenlicht, A. Velcich, and A. Cerutti Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals Science 342 2013 447 453
-
(2013)
Science
, vol.342
, pp. 447-453
-
-
Shan, M.1
Gentile, M.2
Yeiser, J.R.3
Walland, A.C.4
Bornstein, V.U.5
Chen, K.6
He, B.7
Cassis, L.8
Bigas, A.9
Cols, M.10
Comerma, L.11
Huang, B.12
Blander, J.M.13
Xiong, H.14
Mayer, L.15
Berin, C.16
Augenlicht, L.H.17
Velcich, A.18
Cerutti, A.19
-
39
-
-
84890550163
-
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
-
N. Arpaia, C. Campbell, X. Fan, S. Dikiy, J. van der Veeken, P. Deroos, H. Liu, J.R. Cross, K. Pfeffer, P.J. Coffer, and A.Y. Rudensky Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation Nature 2013
-
(2013)
Nature
-
-
Arpaia, N.1
Campbell, C.2
Fan, X.3
Dikiy, S.4
Van Der Veeken, J.5
Deroos, P.6
Liu, H.7
Cross, J.R.8
Pfeffer, K.9
Coffer, P.J.10
Rudensky, A.Y.11
-
40
-
-
84890564250
-
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
-
Y. Furusawa, Y. Obata, S. Fukuda, T.A. Endo, G. Nakato, D. Takahashi, Y. Nakanishi, C. Uetake, K. Kato, T. Kato, M. Takahashi, N.N. Fukuda, S. Murakami, E. Miyauchi, S. Hino, K. Atarashi, S. Onawa, Y. Fujimura, T. Lockett, J.M. Clarke, D.L. Topping, M. Tomita, S. Hori, O. Ohara, T. Morita, H. Koseki, J. Kikuchi, K. Honda, K. Hase, and H. Ohno Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells Nature 2013
-
(2013)
Nature
-
-
Furusawa, Y.1
Obata, Y.2
Fukuda, S.3
Endo, T.A.4
Nakato, G.5
Takahashi, D.6
Nakanishi, Y.7
Uetake, C.8
Kato, K.9
Kato, T.10
Takahashi, M.11
Fukuda, N.N.12
Murakami, S.13
Miyauchi, E.14
Hino, S.15
Atarashi, K.16
Onawa, S.17
Fujimura, Y.18
Lockett, T.19
Clarke, J.M.20
Topping, D.L.21
Tomita, M.22
Hori, S.23
Ohara, O.24
Morita, T.25
Koseki, H.26
Kikuchi, J.27
Honda, K.28
Hase, K.29
Ohno, H.30
more..
-
41
-
-
84892449521
-
Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis
-
N. Singh, A. Gurav, S. Sivaprakasam, E. Brady, R. Padia, H. Shi, M. Thangaraju, P.D. Prasad, S. Manicassamy, D.H. Munn, J.R. Lee, S. Offermanns, and V. Ganapathy Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis Immunity 40 2014 128 139
-
(2014)
Immunity
, vol.40
, pp. 128-139
-
-
Singh, N.1
Gurav, A.2
Sivaprakasam, S.3
Brady, E.4
Padia, R.5
Shi, H.6
Thangaraju, M.7
Prasad, P.D.8
Manicassamy, S.9
Munn, D.H.10
Lee, J.R.11
Offermanns, S.12
Ganapathy, V.13
-
42
-
-
84881068658
-
The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis
-
P.M. Smith, M.R. Howitt, N. Panikov, M. Michaud, C.A. Gallini, Y.M. Bohlooly, J.N. Glickman, and W.S. Garrett The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis Science 341 2013 569 573
-
(2013)
Science
, vol.341
, pp. 569-573
-
-
Smith, P.M.1
Howitt, M.R.2
Panikov, N.3
Michaud, M.4
Gallini, C.A.5
Bohlooly, Y.M.6
Glickman, J.N.7
Garrett, W.S.8
-
43
-
-
79956311926
-
The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota
-
J.L. Round, S.M. Lee, J. Li, G. Tran, B. Jabri, T.A. Chatila, and S.K. Mazmanian The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota Science 332 2011 974 977
-
(2011)
Science
, vol.332
, pp. 974-977
-
-
Round, J.L.1
Lee, S.M.2
Li, J.3
Tran, G.4
Jabri, B.5
Chatila, T.A.6
Mazmanian, S.K.7
-
44
-
-
70049105092
-
Intestinal effector T cells in health and disease
-
C.L. Maynard, and C.T. Weaver Intestinal effector T cells in health and disease Immunity 31 2009 389 400
-
(2009)
Immunity
, vol.31
, pp. 389-400
-
-
Maynard, C.L.1
Weaver, C.T.2
-
45
-
-
84897138296
-
Role of the microbiota in immunity and inflammation
-
Y. Belkaid, and T.W. Hand Role of the microbiota in immunity and inflammation Cell 157 2014 121 141
-
(2014)
Cell
, vol.157
, pp. 121-141
-
-
Belkaid, Y.1
Hand, T.W.2
-
46
-
-
40449091849
-
Commensal gut flora drives the expansion of proinflammatory CD4 T cells in the colonic lamina propria under normal and inflammatory conditions
-
J.H. Niess, R. Leithauser, G. Adler, and J. Reimann Commensal gut flora drives the expansion of proinflammatory CD4 T cells in the colonic lamina propria under normal and inflammatory conditions J. Immunol. 180 2008 559 568
-
(2008)
J. Immunol.
, vol.180
, pp. 559-568
-
-
Niess, J.H.1
Leithauser, R.2
Adler, G.3
Reimann, J.4
-
47
-
-
53349164200
-
Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses
-
J.A. Hall, N. Bouladoux, C.M. Sun, E.A. Wohlfert, R.B. Blank, Q. Zhu, M.E. Grigg, J.A. Berzofsky, and Y. Belkaid Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses Immunity 29 2008 637 649
-
(2008)
Immunity
, vol.29
, pp. 637-649
-
-
Hall, J.A.1
Bouladoux, N.2
Sun, C.M.3
Wohlfert, E.A.4
Blank, R.B.5
Zhu, Q.6
Grigg, M.E.7
Berzofsky, J.A.8
Belkaid, Y.9
-
48
-
-
70350343544
-
Induction of intestinal Th17 cells by segmented filamentous bacteria
-
I.I. Ivanov, K. Atarashi, N. Manel, E.L. Brodie, T. Shima, U. Karaoz, D. Wei, K.C. Goldfarb, C.A. Santee, S.V. Lynch, T. Tanoue, A. Imaoka, K. Itoh, K. Takeda, Y. Umesaki, K. Honda, and D.R. Littman Induction of intestinal Th17 cells by segmented filamentous bacteria Cell 139 2009 485 498
-
(2009)
Cell
, vol.139
, pp. 485-498
-
-
Ivanov, I.I.1
Atarashi, K.2
Manel, N.3
Brodie, E.L.4
Shima, T.5
Karaoz, U.6
Wei, D.7
Goldfarb, K.C.8
Santee, C.A.9
Lynch, S.V.10
Tanoue, T.11
Imaoka, A.12
Itoh, K.13
Takeda, K.14
Umesaki, Y.15
Honda, K.16
Littman, D.R.17
-
49
-
-
84901979873
-
Focused specificity of intestinal T17 cells towards commensal bacterial antigens
-
Y. Yang, M.B. Torchinsky, M. Gobert, H. Xiong, M. Xu, J.L. Linehan, R. Alonzo, C. Ng, A. Chen, X. Lin, A. Sczesnak, J.J. Liao, V.J. Torres, M.K. Jenkins, J.J. Lafaille, and D.R. Littman Focused specificity of intestinal T17 cells towards commensal bacterial antigens Nature 2014
-
(2014)
Nature
-
-
Yang, Y.1
Torchinsky, M.B.2
Gobert, M.3
Xiong, H.4
Xu, M.5
Linehan, J.L.6
Alonzo, R.7
Ng, C.8
Chen, A.9
Lin, X.10
Sczesnak, A.11
Liao, J.J.12
Torres, V.J.13
Jenkins, M.K.14
Lafaille, J.J.15
Littman, D.R.16
-
50
-
-
84898679249
-
Segmented filamentous bacteria antigens presented by intestinal dendritic cells drive mucosal thl7 cell differentiation
-
Y. Goto, C. Panea, G. Nakato, A. Cebula, C. Lee, M.G. Diez, T.M. Laufer, L. Ignatowicz, and I.I. Ivanov Segmented filamentous bacteria antigens presented by intestinal dendritic cells drive mucosal thl7 cell differentiation Immunity 40 2014 594 607
-
(2014)
Immunity
, vol.40
, pp. 594-607
-
-
Goto, Y.1
Panea, C.2
Nakato, G.3
Cebula, A.4
Lee, C.5
Diez, M.G.6
Laufer, T.M.7
Ignatowicz, L.8
Ivanov, I.I.9
-
51
-
-
77955391804
-
TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
-
R.A. Gottschalk, E. Corse, and J.P. Allison TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo J. Exp. Med. 207 2010 1701 1711
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1701-1711
-
-
Gottschalk, R.A.1
Corse, E.2
Allison, J.P.3
-
52
-
-
77954104660
-
Dominant role of antigen dose in CD4+Foxp3+ regulatory T cell induction and expansion
-
M.S. Turner, L.P. Kane, and P.A. Morel Dominant role of antigen dose in CD4+Foxp3+ regulatory T cell induction and expansion J. Immunol. 183 2009 4895 4903
-
(2009)
J. Immunol.
, vol.183
, pp. 4895-4903
-
-
Turner, M.S.1
Kane, L.P.2
Morel, P.A.3
-
53
-
-
84866436436
-
Acute gastrointestinal infection induces long-lived microbiota-specific T cell responses
-
T.W. Hand, L.M. Dos Santos, N. Bouladoux, M.J. Molloy, A.J. Pagan, M. Pepper, C.L. Maynard, C.O. Elson 3rd, and Y. Belkaid Acute gastrointestinal infection induces long-lived microbiota-specific T cell responses Science 337 2012 1553 1556
-
(2012)
Science
, vol.337
, pp. 1553-1556
-
-
Hand, T.W.1
Dos Santos, L.M.2
Bouladoux, N.3
Molloy, M.J.4
Pagan, A.J.5
Pepper, M.6
Maynard, C.L.7
Elson, C.O.8
Belkaid, Y.9
-
54
-
-
79951772860
-
Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria
-
U. Hadis, B. Wahl, O. Schulz, M. Hardtke-Wolenski, A. Schippers, N. Wagner, W. Muller, T. Sparwasser, R. Forster, and O. Pabst Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria Immunity 34 2011 237 246
-
(2011)
Immunity
, vol.34
, pp. 237-246
-
-
Hadis, U.1
Wahl, B.2
Schulz, O.3
Hardtke-Wolenski, M.4
Schippers, A.5
Wagner, N.6
Muller, W.7
Sparwasser, T.8
Forster, R.9
Pabst, O.10
-
55
-
-
77952684481
-
Gamma interferon produced by antigen-specific CD4+ T cells regulates the mucosal immune responses to Citrobacter rodentium infection
-
H. Shiomi, A. Masuda, S. Nishiumi, M. Nishida, T. Takagawa, Y. Shiomi, H. Kutsumi, R.S. Blumberg, T. Azuma, and M. Yoshida Gamma interferon produced by antigen-specific CD4+ T cells regulates the mucosal immune responses to Citrobacter rodentium infection Infect. Immun. 78 2010 2653 2666
-
(2010)
Infect. Immun.
, vol.78
, pp. 2653-2666
-
-
Shiomi, H.1
Masuda, A.2
Nishiumi, S.3
Nishida, M.4
Takagawa, T.5
Shiomi, Y.6
Kutsumi, H.7
Blumberg, R.S.8
Azuma, T.9
Yoshida, M.10
-
56
-
-
84860557017
-
MyD88 is critically involved in immune tolerance breakdown at environmental interfaces of Foxp3-deficient mice
-
M.N. Rivas, Y.T. Koh, A. Chen, A. Nguyen, Y.H. Lee, G. Lawson, and T.A. Chatila MyD88 is critically involved in immune tolerance breakdown at environmental interfaces of Foxp3-deficient mice J. Clin. Investig. 122 2012 1933 1947
-
(2012)
J. Clin. Investig.
, vol.122
, pp. 1933-1947
-
-
Rivas, M.N.1
Koh, Y.T.2
Chen, A.3
Nguyen, A.4
Lee, Y.H.5
Lawson, G.6
Chatila, T.A.7
-
57
-
-
33747114270
-
Role of toll-like receptors in spontaneous commensal-dependent colitis
-
S. Rakoff-Nahoum, L. Hao, and R. Medzhitov Role of toll-like receptors in spontaneous commensal-dependent colitis Immunity 2006
-
(2006)
Immunity
-
-
Rakoff-Nahoum, S.1
Hao, L.2
Medzhitov, R.3
-
58
-
-
64149088746
-
Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity
-
S. Manicassamy, R. Ravindran, J. Deng, H. Oluoch, T.L. Denning, S.P. Kasturi, K.M. Rosenthal, B.D. Evavold, and B. Pulendran Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity Nat. Med. 15 2009 401 409
-
(2009)
Nat. Med.
, vol.15
, pp. 401-409
-
-
Manicassamy, S.1
Ravindran, R.2
Deng, J.3
Oluoch, H.4
Denning, T.L.5
Kasturi, S.P.6
Rosenthal, K.M.7
Evavold, B.D.8
Pulendran, B.9
-
59
-
-
84867959354
-
Regulatory role of suppressive motifs from commensal DNA
-
N. Bouladoux, J.A. Hall, J.R. Grainger, L.M. dos Santos, M.G. Kann, V. Nagarajan, D. Verthelyi, and Y. Belkaid Regulatory role of suppressive motifs from commensal DNA Mucosal Immunol. 5 2012 623 634
-
(2012)
Mucosal Immunol.
, vol.5
, pp. 623-634
-
-
Bouladoux, N.1
Hall, J.A.2
Grainger, J.R.3
Dos Santos, L.M.4
Kann, M.G.5
Nagarajan, V.6
Verthelyi, D.7
Belkaid, Y.8
-
60
-
-
3242664636
-
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
-
S. Rakoff-Nahoum, J. Paglino, F. Eslami-Varzaneh, S. Edberg, and R. Medzhitov Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis Cell 118 2004 229 241
-
(2004)
Cell
, vol.118
, pp. 229-241
-
-
Rakoff-Nahoum, S.1
Paglino, J.2
Eslami-Varzaneh, F.3
Edberg, S.4
Medzhitov, R.5
-
61
-
-
44349167059
-
Dendritic cells in intestinal immune regulation
-
J.L. Coombes, and F. Powrie Dendritic cells in intestinal immune regulation Nat. Rev. Immunol. 8 2008 435 446
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 435-446
-
-
Coombes, J.L.1
Powrie, F.2
-
62
-
-
84897938213
-
Contextual functions of antigen-presenting cells in the gastrointestinal tract
-
J.R. Grainger, M.H. Askenase, F. Guimont-Desrochers, D.M. da Fonseca, and Y. Belkaid Contextual functions of antigen-presenting cells in the gastrointestinal tract Immunol. Rev. 259 2014 75 87
-
(2014)
Immunol. Rev.
, vol.259
, pp. 75-87
-
-
Grainger, J.R.1
Askenase, M.H.2
Guimont-Desrochers, F.3
Da Fonseca, D.M.4
Belkaid, Y.5
-
63
-
-
84857444876
-
Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense
-
M.A. Kinnebrew, C.G. Buffie, G.E. Diehl, L.A. Zenewicz, I. Leiner, T.M. Hohl, R.A. Flavell, D.R. Littman, and E.G. Pamer Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense Immunity 36 2012 276 287
-
(2012)
Immunity
, vol.36
, pp. 276-287
-
-
Kinnebrew, M.A.1
Buffie, C.G.2
Diehl, G.E.3
Zenewicz, L.A.4
Leiner, I.5
Hohl, T.M.6
Flavell, R.A.7
Littman, D.R.8
Pamer, E.G.9
-
64
-
-
84883172356
-
Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens
-
A.T. Satpathy, C.G. Briseno, J.S. Lee, D. Ng, N.A. Manieri, W. Kc, X. Wu, S.R. Thomas, W.L. Lee, M. Turkoz, K.G. McDonald, M.M. Meredith, C. Song, C.J. Guidos, R.D. Newberry, W. Ouyang, T.L. Murphy, T.S. Stappenbeck, J.L. Gommerman, M.C. Nussenzweig, M. Colonna, R. Kopan, and K.M. Murphy Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens Nat. Immunol. 14 2013 937 948
-
(2013)
Nat. Immunol.
, vol.14
, pp. 937-948
-
-
Satpathy, A.T.1
Briseno, C.G.2
Lee, J.S.3
Ng, D.4
Manieri, N.A.5
Kc, W.6
Wu, X.7
Thomas, S.R.8
Lee, W.L.9
Turkoz, M.10
McDonald, K.G.11
Meredith, M.M.12
Song, C.13
Guidos, C.J.14
Newberry, R.D.15
Ouyang, W.16
Murphy, T.L.17
Stappenbeck, T.S.18
Gommerman, J.L.19
Nussenzweig, M.C.20
Colonna, M.21
Kopan, R.22
Murphy, K.M.23
more..
-
65
-
-
84885447087
-
Intestinal lamina propria dendritic cells maintain T cell homeostasis but do not affect commensalism
-
N.E. Welty, C. Staley, N. Ghilardi, M.J. Sadowsky, B.Z. Igyarto, and D.H. Kaplan Intestinal lamina propria dendritic cells maintain T cell homeostasis but do not affect commensalism J. Exp. Med. 210 2013 2011 2024
-
(2013)
J. Exp. Med.
, vol.210
, pp. 2011-2024
-
-
Welty, N.E.1
Staley, C.2
Ghilardi, N.3
Sadowsky, M.J.4
Igyarto, B.Z.5
Kaplan, D.H.6
-
66
-
-
81955164775
-
Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine
-
K.L. Lewis, M.L. Caton, M. Bogunovic, M. Greter, L.T. Grajkowska, D. Ng, A. Klinakis, I.R. Charo, S. Jung, J.L. Gommerman, I.I. Ivanov, K. Liu, M. Merad, and B. Reizis Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine Immunity 35 2011 780 791
-
(2011)
Immunity
, vol.35
, pp. 780-791
-
-
Lewis, K.L.1
Caton, M.L.2
Bogunovic, M.3
Greter, M.4
Grajkowska, L.T.5
Ng, D.6
Klinakis, A.7
Charo, I.R.8
Jung, S.9
Gommerman, J.L.10
Ivanov, I.I.11
Liu, K.12
Merad, M.13
Reizis, B.14
-
67
-
-
84875225901
-
Contributions of dendritic cells and macrophages to intestinal homeostasis and immune defense
-
J. Farache, E. Zigmond, G. Shakhar, and S. Jung Contributions of dendritic cells and macrophages to intestinal homeostasis and immune defense Immunol. Cellbiol. 91 2013 232 239
-
(2013)
Immunol. Cellbiol.
, vol.91
, pp. 232-239
-
-
Farache, J.1
Zigmond, E.2
Shakhar, G.3
Jung, S.4
-
68
-
-
84900428511
-
Interleukin-10 receptor signaling in innate immune cells regulates mucosal immune tolerance and anti-inflammatory macrophage function
-
D.S. Shouval, A. Biswas, J.A. Goettel, K. McCann, E. Conaway, N.S. Redhu, I.D. Mascanfroni, Z. Al Adham, S. Lavoie, M. Ibourk, D.D. Nguyen, J.N. Samsom, J.C. Escher, R. Somech, B. Weiss, R. Beier, L.S. Conklin, C.L. Ebens, F.G. Santos, A.R. Ferreira, M. Sherlock, A.K. Bhan, W. Muller, J.R. Mora, F.J. Quintana, C. Klein, A.M. Muise, B.H. Horwitz, and S.B. Snapper Interleukin-10 receptor signaling in innate immune cells regulates mucosal immune tolerance and anti-inflammatory macrophage function Immunity 2014
-
(2014)
Immunity
-
-
Shouval, D.S.1
Biswas, A.2
Goettel, J.A.3
McCann, K.4
Conaway, E.5
Redhu, N.S.6
Mascanfroni, I.D.7
Al Adham, Z.8
Lavoie, S.9
Ibourk, M.10
Nguyen, D.D.11
Samsom, J.N.12
Escher, J.C.13
Somech, R.14
Weiss, B.15
Beier, R.16
Conklin, L.S.17
Ebens, C.L.18
Santos, F.G.19
Ferreira, A.R.20
Sherlock, M.21
Bhan, A.K.22
Muller, W.23
Mora, J.R.24
Quintana, F.J.25
Klein, C.26
Muise, A.M.27
Horwitz, B.H.28
Snapper, S.B.29
more..
-
69
-
-
84897053496
-
Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis
-
A. Mortha, A. Chudnovskiy, D. Hashimoto, M. Bogunovic, S.P. Spencer, Y. Belkaid, and M. Merad Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis Science 343 2014 1249288
-
(2014)
Science
, vol.343
, pp. 1249288
-
-
Mortha, A.1
Chudnovskiy, A.2
Hashimoto, D.3
Bogunovic, M.4
Spencer, S.P.5
Belkaid, Y.6
Merad, M.7
-
70
-
-
84878737123
-
Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria
-
M.R. Hepworth, L.A. Monticelli, T.C. Fung, C.G. Ziegler, S. Grunberg, R. Sinha, A.R. Mantegazza, H.L. Ma, A. Crawford, J.M. Angelosanto, E.J. Wherry, P.A. Koni, F.D. Bushman, C.O. Elson, G. Eberl, D. Artis, and G.F. Sonnenberg Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria Nature 498 2013 113 117
-
(2013)
Nature
, vol.498
, pp. 113-117
-
-
Hepworth, M.R.1
Monticelli, L.A.2
Fung, T.C.3
Ziegler, C.G.4
Grunberg, S.5
Sinha, R.6
Mantegazza, A.R.7
Ma, H.L.8
Crawford, A.9
Angelosanto, J.M.10
Wherry, E.J.11
Koni, P.A.12
Bushman, F.D.13
Elson, C.O.14
Eberl, G.15
Artis, D.16
Sonnenberg, G.F.17
-
71
-
-
84866523733
-
Compromised intestinal epithelial barrier induces adaptive immune compensation that protects from colitis
-
M. Khounlotham, W. Kim, E. Peatman, P. Nava, O. Medina-Contreras, C. Addis, S. Koch, B. Fournier, A. Nusrat, T.L. Denning, and C.A. Parkos Compromised intestinal epithelial barrier induces adaptive immune compensation that protects from colitis Immunity 37 2012 563 573
-
(2012)
Immunity
, vol.37
, pp. 563-573
-
-
Khounlotham, M.1
Kim, W.2
Peatman, E.3
Nava, P.4
Medina-Contreras, O.5
Addis, C.6
Koch, S.7
Fournier, B.8
Nusrat, A.9
Denning, T.L.10
Parkos, C.A.11
-
72
-
-
1242296822
-
Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut
-
K. Suzuki, B. Meek, Y. Doi, M. Muramatsu, T. Chiba, T. Honjo, and S. Fagarasan Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut Proc. Natl. Acad. Sci. USA 101 2004 1981 1986
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1981-1986
-
-
Suzuki, K.1
Meek, B.2
Doi, Y.3
Muramatsu, M.4
Chiba, T.5
Honjo, T.6
Fagarasan, S.7
-
73
-
-
84861989207
-
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria
-
G.R. Sonnenberg, L.A. Monticelli, T. Alenghat, T.C. Fung, N.A. Hutnick, J. Kunisawa, N. Shibata, S. Grunberg, R. Sinha, A.M. Zahm, M.R. Tardif, T. Sathaliyawala, M. Kubota, D.L. Farber, R.G. Collman, A. Shaked, L.A. Fouser, D.B. Weiner, P.A. Tessier, J.R. Friedman, H. Kiyono, F.D. Bushman, and K.M. Chang Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria Science 336 2012 1321 1325
-
(2012)
Science
, vol.336
, pp. 1321-1325
-
-
Sonnenberg, G.R.1
Monticelli, L.A.2
Alenghat, T.3
Fung, T.C.4
Hutnick, N.A.5
Kunisawa, J.6
Shibata, N.7
Grunberg, S.8
Sinha, R.9
Zahm, A.M.10
Tardif, M.R.11
Sathaliyawala, T.12
Kubota, M.13
Farber, D.L.14
Collman, R.G.15
Shaked, A.16
Fouser, L.A.17
Weiner, D.B.18
Tessier, P.A.19
Friedman, J.R.20
Kiyono, H.21
Bushman, F.D.22
Chang, K.M.23
more..
-
74
-
-
34848889673
-
Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system
-
W.S. Garrett, G.M. Lord, S. Punit, G. Lugo-Villarino, S.K. Mazmanian, S. Ito, J.N. Glickman, and L.H. Glimcher Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system Cell 131 2007 33 45
-
(2007)
Cell
, vol.131
, pp. 33-45
-
-
Garrett, W.S.1
Lord, G.M.2
Punit, S.3
Lugo-Villarino, G.4
Mazmanian, S.K.5
Ito, S.6
Glickman, J.N.7
Glimcher, L.H.8
-
75
-
-
33646560950
-
Transforming growth factor-beta induces development of the T(H)17 lineage
-
P.R. Mangan, L.E. Harrington, D.B. O'Quinn, W.S. Helms, D.C. Bullard, C.O. Elson, R.D. Hatton, S.M. Wahl, T.R. Schoeb, and C.T. Weaver Transforming growth factor-beta induces development of the T(H)17 lineage Nature 441 2006 231 234
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'Quinn, D.B.3
Helms, W.S.4
Bullard, D.C.5
Elson, C.O.6
Hatton, R.D.7
Wahl, S.M.8
Schoeb, T.R.9
Weaver, C.T.10
-
76
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
-
I.I. Ivanov, B.S. McKenzie, L. Zhou, C.E. Tadokoro, A. Lepelley, J.J. Lafaille, D.J. Cua, and D.R. Littman The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells Cell 126 2006 1121 1133
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
Lafaille, J.J.6
Cua, D.J.7
Littman, D.R.8
-
78
-
-
84255162082
-
Th17 cells mediate clade-specific, serotype-independent mucosal immunity
-
K. Chen, J.P. McAleer, Y. Lin, D.L. Paterson, M. Zheng, J.R. Alcorn, C.T. Weaver, and J.K. Kolls Th17 cells mediate clade-specific, serotype-independent mucosal immunity Immunity 35 2011 997 1009
-
(2011)
Immunity
, vol.35
, pp. 997-1009
-
-
Chen, K.1
McAleer, J.P.2
Lin, Y.3
Paterson, D.L.4
Zheng, M.5
Alcorn, J.R.6
Weaver, C.T.7
Kolls, J.K.8
-
79
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25)
-
S. Sakaguchi, N. Sakaguchi, M. Asano, M. Itoh, and M. Toda Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25) J. Immunol. 155 1995 1151 1164
-
(1995)
J. Immunol.
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
80
-
-
33846485153
-
Regulatory T cells prevent catastrophic auto immunity throughout the lifespan of mice
-
J.M. Kim, J.P. Rasmussen, and A.Y. Rudensky Regulatory T cells prevent catastrophic auto immunity throughout the lifespan of mice Nat. Immunol. 8 2007 191 197
-
(2007)
Nat. Immunol.
, vol.8
, pp. 191-197
-
-
Kim, J.M.1
Rasmussen, J.P.2
Rudensky, A.Y.3
-
81
-
-
84888869495
-
Stratification and compartmentalisation of immunoglobulin responses to commensal intestinal microbes
-
A.J. Macpherson, and K.D. McCoy Stratification and compartmentalisation of immunoglobulin responses to commensal intestinal microbes Semin. Immunol. 25 2013 358 363
-
(2013)
Semin. Immunol.
, vol.25
, pp. 358-363
-
-
Macpherson, A.J.1
McCoy, K.D.2
-
82
-
-
84858607062
-
Systemic antibody responses to gut microbes in health and disease
-
K. Zimmermann, A. Haas, and A. Oxenius Systemic antibody responses to gut microbes in health and disease Gut Microbes 3 2012 42 47
-
(2012)
Gut Microbes
, vol.3
, pp. 42-47
-
-
Zimmermann, K.1
Haas, A.2
Oxenius, A.3
-
83
-
-
79955494239
-
The majority of intestinal IgA+ and IgG+ plasmablasts in the human gut are antigen-specific
-
J. Benckert, N. Schmolka, C. Kreschel, M.J. Zoller, A. Sturm, B. Wiedenmann, and H. Wardemann The majority of intestinal IgA+ and IgG+ plasmablasts in the human gut are antigen-specific J. Clin. Investig. 121 2011 1946 1955
-
(2011)
J. Clin. Investig.
, vol.121
, pp. 1946-1955
-
-
Benckert, J.1
Schmolka, N.2
Kreschel, C.3
Zoller, M.J.4
Sturm, A.5
Wiedenmann, B.6
Wardemann, H.7
-
85
-
-
0034705397
-
A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria
-
A.J. Macpherson, D. Gatto, E. Sainsbury, G.R. Harriman, H. Hengartner, and R.M. Zinkernagel A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria Science 288 2000 2222 2226
-
(2000)
Science
, vol.288
, pp. 2222-2226
-
-
Macpherson, A.J.1
Gatto, D.2
Sainsbury, E.3
Harriman, G.R.4
Hengartner, H.5
Zinkernagel, R.M.6
-
86
-
-
84856872027
-
Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine
-
C. Lindner, B. Wahl, L. Fohse, S. Suerbaum, A.J. Macpherson, I. Prinz, and O. Pabst Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine J. Exp. Med. 209 2012 365 377
-
(2012)
J. Exp. Med.
, vol.209
, pp. 365-377
-
-
Lindner, C.1
Wahl, B.2
Fohse, L.3
Suerbaum, S.4
Macpherson, A.J.5
Prinz, I.6
Pabst, O.7
-
87
-
-
73349099737
-
A dominant, coordinated T regulatory cell-Ig A response to the intestinal microbiota
-
Y. Cong, T. Feng, K. Fujihashi, T.R. Schoeb, and C.O. Elson A dominant, coordinated T regulatory cell-Ig A response to the intestinal microbiota Proc. Natl. Acad. Sci. USA 106 2009 19256 19261
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 19256-19261
-
-
Cong, Y.1
Feng, T.2
Fujihashi, K.3
Schoeb, T.R.4
Elson, C.O.5
-
88
-
-
62449202866
-
Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches
-
M. Tsuji, N. Komatsu, S. Kawamoto, K. Suzuki, O. Kanagawa, T. Honjo, S. Hori, and S. Fagarasan Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches Science 323 2009 1488 1492
-
(2009)
Science
, vol.323
, pp. 1488-1492
-
-
Tsuji, M.1
Komatsu, N.2
Kawamoto, S.3
Suzuki, K.4
Kanagawa, O.5
Honjo, T.6
Hori, S.7
Fagarasan, S.8
-
89
-
-
79961151137
-
Foxp3+ follicular regulatory T cells control the germinal center response
-
M.A. Linterman, W. Pierson, S.K. Lee, A. Kallies, S. Kawamoto, T.F. Rayner, M. Srivastava, D.P. Divekar, L. Beaton, J.J. Hogan, S. Fagarasan, A. Liston, K.G. Smith, and C.G. Vinuesa Foxp3+ follicular regulatory T cells control the germinal center response Nat. Med. 17 2011 975 982
-
(2011)
Nat. Med.
, vol.17
, pp. 975-982
-
-
Linterman, M.A.1
Pierson, W.2
Lee, S.K.3
Kallies, A.4
Kawamoto, S.5
Rayner, T.F.6
Srivastava, M.7
Divekar, D.P.8
Beaton, L.9
Hogan, J.J.10
Fagarasan, S.11
Liston, A.12
Smith, K.G.13
Vinuesa, C.G.14
-
90
-
-
79961158055
-
Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
-
Y. Chung, S. Tanaka, F. Chu, R.I. Nurieva, G.J. Martinez, S. Rawal, Y.H. Wang, H. Lim, J.M. Reynolds, X.H. Zhou, H.M. Fan, Z.M. Liu, S.S. Neelapu, and C. Dong Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions Nat. Med. 17 2011 983 988
-
(2011)
Nat. Med.
, vol.17
, pp. 983-988
-
-
Chung, Y.1
Tanaka, S.2
Chu, F.3
Nurieva, R.I.4
Martinez, G.J.5
Rawal, S.6
Wang, Y.H.7
Lim, H.8
Reynolds, J.M.9
Zhou, X.H.10
Fan, H.M.11
Liu, Z.M.12
Neelapu, S.S.13
Dong, C.14
-
91
-
-
84898685253
-
Segmented filamentous bacterium uses secondary and tertiary lymphoid tissues to induce gut IgA and specific T helper 17 cell responses
-
E. Lecuyer, S. Rakotobe, H. Lengline-Garnier, C. Lebreton, M. Picard, C. Juste, R. Fritzen, G. Eberl, K.D. McCoy, A.J. Macpherson, C.A. Reynaud, N. Cerf-Bensussan, and V. Gaboriau-Routhiau Segmented filamentous bacterium uses secondary and tertiary lymphoid tissues to induce gut IgA and specific T helper 17 cell responses Immunity 40 2014 608 620
-
(2014)
Immunity
, vol.40
, pp. 608-620
-
-
Lecuyer, E.1
Rakotobe, S.2
Lengline-Garnier, H.3
Lebreton, C.4
Picard, M.5
Juste, C.6
Fritzen, R.7
Eberl, G.8
McCoy, K.D.9
Macpherson, A.J.10
Reynaud, C.A.11
Cerf-Bensussan, N.12
Gaboriau-Routhiau, V.13
-
92
-
-
84875473675
-
Plasticity of Th17 cells in Peyer's patches is responsible for the induction of T cell-dependent IgA responses
-
K. Hirota, J.E. Turner, M. Villa, J.H. Duarte, J. Demengeot, O.M. Steinmetz, and B. Stockinger Plasticity of Th17 cells in Peyer's patches is responsible for the induction of T cell-dependent IgA responses Nat. Immunol. 14 2013 372 379
-
(2013)
Nat. Immunol.
, vol.14
, pp. 372-379
-
-
Hirota, K.1
Turner, J.E.2
Villa, M.3
Duarte, J.H.4
Demengeot, J.5
Steinmetz, O.M.6
Stockinger, B.7
-
93
-
-
77954051526
-
Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses
-
S. Hapfelmeier, M.A. Lawson, E. Slack, J.K. Kirundi, M. Stoel, M. Heikenwalder, J. Cahenzli, Y. Velykoredko, M.L. Balmer, K. Endt, M.B. Geuking, R. Curtiss 3rd, K.D. McCoy, and A.J. Macpherson Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses Science 328 2010 1705 1709
-
(2010)
Science
, vol.328
, pp. 1705-1709
-
-
Hapfelmeier, S.1
Lawson, M.A.2
Slack, E.3
Kirundi, J.K.4
Stoel, M.5
Heikenwalder, M.6
Cahenzli, J.7
Velykoredko, Y.8
Balmer, M.L.9
Endt, K.10
Geuking, M.B.11
Curtiss, R.12
McCoy, K.D.13
Macpherson, A.J.14
-
94
-
-
48749100460
-
APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa
-
B. Huard, T. McKee, C. Bosshard, S. Durual, T. Matthes, S. Myit, O. Donze, C. Frossard, C. Chizzolini, C. Favre, R. Zubler, J.P. Guyot, P. Schneider, and E. Roosnek APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa J. Clin. Investig. 118 2008 2887 2895
-
(2008)
J. Clin. Investig.
, vol.118
, pp. 2887-2895
-
-
Huard, B.1
McKee, T.2
Bosshard, C.3
Durual, S.4
Matthes, T.5
Myit, S.6
Donze, O.7
Frossard, C.8
Chizzolini, C.9
Favre, C.10
Zubler, R.11
Guyot, J.P.12
Schneider, P.13
Roosnek, E.14
-
95
-
-
84880967962
-
A functional BCR in human IgA and IgM plasma cells
-
D. Pinto, E. Montani, M. Bolli, G. Garavaglia, F. Sallusto, A. Lanzavecchia, and D. Jarrossay A functional BCR in human IgA and IgM plasma cells Blood 121 2013 4110 4114
-
(2013)
Blood
, vol.121
, pp. 4110-4114
-
-
Pinto, D.1
Montani, E.2
Bolli, M.3
Garavaglia, G.4
Sallusto, F.5
Lanzavecchia, A.6
Jarrossay, D.7
-
96
-
-
59649118664
-
Antigen-specific peripheral shaping of the natural regulatory T cell population
-
S.K. Lathrop, N.A. Santacruz, D. Pham, J. Luo, and C.S. Hsieh Antigen-specific peripheral shaping of the natural regulatory T cell population J. Exp. Med. 205 2008 3105 3117
-
(2008)
J. Exp. Med.
, vol.205
, pp. 3105-3117
-
-
Lathrop, S.K.1
Santacruz, N.A.2
Pham, D.3
Luo, J.4
Hsieh, C.S.5
-
97
-
-
33746329271
-
The role of physiological self-antigen in the acquisition and maintenance of regulatory T-cell function
-
E.T. Samy, Y.Y. Setiady, K. Ohno, P. Pramoonjago, C. Sharp, and K.S. Tung The role of physiological self-antigen in the acquisition and maintenance of regulatory T-cell function Immunol. Rev. 212 2006 170 184
-
(2006)
Immunol. Rev.
, vol.212
, pp. 170-184
-
-
Samy, E.T.1
Setiady, Y.Y.2
Ohno, K.3
Pramoonjago, P.4
Sharp, C.5
Tung, K.S.6
-
98
-
-
53349173070
-
Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine
-
I.I. Ivanov, L. Frutos Rde, N. Manel, K. Yoshinaga, D.B. Rifkin, R.B. Sartor, B.B. Finlay, and D.R. Littman Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine Cell Host Microbe 4 2008 337 349
-
(2008)
Cell Host Microbe
, vol.4
, pp. 337-349
-
-
Ivanov, I.I.1
Frutos Rde, L.2
Manel, N.3
Yoshinaga, K.4
Rifkin, D.B.5
Sartor, R.B.6
Finlay, B.B.7
Littman, D.R.8
-
99
-
-
38849178169
-
CD4+ T cells transfer resistance against Citrobacter rodentium-induced infectious colitis by induction of Th 1 immunity
-
T.W. Spahn, M. Ross, C. von Eiff, C. Maaser, T. Spieker, K. Kannengiesser, W. Domschke, and T. Kucharzik CD4+ T cells transfer resistance against Citrobacter rodentium-induced infectious colitis by induction of Th 1 immunity Scand. J. Immunol. 67 2008 238 244
-
(2008)
Scand. J. Immunol.
, vol.67
, pp. 238-244
-
-
Spahn, T.W.1
Ross, M.2
Von Eiff, C.3
Maaser, C.4
Spieker, T.5
Kannengiesser, K.6
Domschke, W.7
Kucharzik, T.8
-
100
-
-
84355162741
-
Response to self antigen imprints regulatory memory in tissues
-
M.D. Rosenblum, I.K. Gratz, J.S. Paw, K. Lee, A. Marshak-Rothstein, and A.K. Abbas Response to self antigen imprints regulatory memory in tissues Nature 480 2011 538 542
-
(2011)
Nature
, vol.480
, pp. 538-542
-
-
Rosenblum, M.D.1
Gratz, I.K.2
Paw, J.S.3
Lee, K.4
Marshak-Rothstein, A.5
Abbas, A.K.6
-
101
-
-
77955890952
-
Interleukin-23 drives intestinal inflammation through direct activity on T cells
-
P.P. Ahern, C. Schiering, S. Buonocore, M.J. McGeachy, D.J. Cua, K.J. Maloy, and F. Powrie Interleukin-23 drives intestinal inflammation through direct activity on T cells Immunity 33 2010 279 288
-
(2010)
Immunity
, vol.33
, pp. 279-288
-
-
Ahern, P.P.1
Schiering, C.2
Buonocore, S.3
McGeachy, M.J.4
Cua, D.J.5
Maloy, K.J.6
Powrie, F.7
-
102
-
-
79952389800
-
Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens
-
R.W. DePaolo, V. Abadie, R. Tang, H. Fehlner-Peach, J.A. Hall, W. Wang, E.V. Marietta, D.D. Kasarda, T.A. Waldmann, J.A. Murray, C. Semrad, S.S. Kupfer, Y. Belkaid, S. Guandalini, and B. Jabri Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens Nature 471 2011 220 224
-
(2011)
Nature
, vol.471
, pp. 220-224
-
-
Depaolo, R.W.1
Abadie, V.2
Tang, R.3
Fehlner-Peach, H.4
Hall, J.A.5
Wang, W.6
Marietta, E.V.7
Kasarda, D.D.8
Waldmann, T.A.9
Murray, J.A.10
Semrad, C.11
Kupfer, S.S.12
Belkaid, Y.13
Guandalini, S.14
Jabri, B.15
-
103
-
-
79952740974
-
Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha
-
J.A. Hall, J.L. Cannons, J.R. Grainger, L.M. Dos Santos, T.W. Hand, S. Naik, E.A. Wohlfert, D.B. Chou, G. Oldenhove, M. Robinson, M.E. Grigg, R. Kastenmayer, P.L. Schwartzberg, and Y. Belkaid Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha Immunity 34 2011 435 447
-
(2011)
Immunity
, vol.34
, pp. 435-447
-
-
Hall, J.A.1
Cannons, J.L.2
Grainger, J.R.3
Dos Santos, L.M.4
Hand, T.W.5
Naik, S.6
Wohlfert, E.A.7
Chou, D.B.8
Oldenhove, G.9
Robinson, M.10
Grigg, M.E.11
Kastenmayer, R.12
Schwartzberg, P.L.13
Belkaid, Y.14
-
104
-
-
84879564304
-
Specific gut commensal flora locally alters T cell tuning to endogenous ligands
-
P. Chappert, N. Bouladoux, S. Naik, and R.H. Schwartz Specific gut commensal flora locally alters T cell tuning to endogenous ligands Immunity 38 2013 1198 1210
-
(2013)
Immunity
, vol.38
, pp. 1198-1210
-
-
Chappert, P.1
Bouladoux, N.2
Naik, S.3
Schwartz, R.H.4
-
105
-
-
80052845560
-
Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis
-
C. Gunther, E. Martini, N. Wittkopf, K. Amann, B. Weigmann, H. Neumann, M.J. Waldner, S.M. Hedrick, S. Tenzer, M.F. Neurath, and C. Becker Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis Nature 411 2011 335 339
-
(2011)
Nature
, vol.411
, pp. 335-339
-
-
Gunther, C.1
Martini, E.2
Wittkopf, N.3
Amann, K.4
Weigmann, B.5
Neumann, H.6
Waldner, M.J.7
Hedrick, S.M.8
Tenzer, S.9
Neurath, M.F.10
Becker, C.11
-
106
-
-
80052850704
-
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
-
P.S. Welz, A. Wullaert, K. Vlantis, V. Kondylis, V. Fernandez-Majada, M. Ermolaeva, P. Kirsch, A. Sterner-Kock, G. van Loo, and M. Pasparakis FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation Nature 477 2011 330 334
-
(2011)
Nature
, vol.477
, pp. 330-334
-
-
Welz, P.S.1
Wullaert, A.2
Vlantis, K.3
Kondylis, V.4
Fernandez-Majada, V.5
Ermolaeva, M.6
Kirsch, P.7
Sterner-Kock, A.8
Van Loo, G.9
Pasparakis, M.10
-
107
-
-
36549001139
-
The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States
-
M.D. Kappelman, S.L. Rifas-Shiman, K. Kleinman, D. Ollendorf, A. Bousvaros, R.J. Grand, and J.A. Finkelstein The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States Clin. Gastroenterol. Hepatol. 5 2007 1424 1429
-
(2007)
Clin. Gastroenterol. Hepatol.
, vol.5
, pp. 1424-1429
-
-
Kappelman, M.D.1
Rifas-Shiman, S.L.2
Kleinman, K.3
Ollendorf, D.4
Bousvaros, A.5
Grand, R.J.6
Finkelstein, J.A.7
-
108
-
-
84868336049
-
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
-
L. Jostins, S. Ripke, R.K. Weersma, R.H. Duerr, D. McGovern, K.Y. Phui, J.C. Lee, L.P. Schumm, Y. Sharma, C.A. Anderson, J. Essers, M. Mitrovic, K. Ning, I. Cleynen, E. Theatre, S.L. Spain, S. Raychaudhuri, P. Goyette, Z. Wei, C. Abraham, J.P. Achkar, T. Ahmad, L. Amininejad, A.N. Ananthakrishnan, V. Andersen, J.M. Andrews, L. Baidoo, T. Balschun, P.A. Bampton, A. Bitton, G. Boucher, S. Brand, C. Buning, A. Cohain, S. Cichon, M. D'Amato, D. De Jong, K.L. Devaney, M. Dubinsky, C. Edwards, D. Ellinghaus, L.R. Ferguson, D. Franchimont, K. Fransen, R. Gearry, M. Georges, C. Gieger, J. Glas, T. Haritunians, A. Hart, C. Hawkey, M. Hedl, X. Hu, T.H. Karlsen, L. Kupcinskas, S. Kugathasan, A. Latiano, D. Laukens, I.C. Lawrance, C.W. Lees, E. Louis, Mahy, G., J. Mansfield, A.R. Morgan, C. Mowat, W. Newman, O. Palmieri, C.Y. Ponsioen, U. Potocnik, N.J. Prescott, M. Regueiro, J.I. Rotter, R.K. Russell, J.D. Sanderson, M. Sans, J. Satsangi, S. Schreiber, L.A. Simms, J. Sventoraityte, S.R. Targan, K.D. Taylor, M. Tremelling, H.W. Verspaget, M. De vos, C. Wijmenga, D.C. Wilson, J. Winkelmann, R.J. Xavier, S. Zeissig, B. Zhang, C.K. Zhang, H. Zhao, I.B.D.G.C. International, M.S. Silverberg, V. Annese, H. Hakonarson, S.R. Brant, G. Radford-Smith, C.G. Mathew, and J.D. Rioux Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease Nature 491 2012 119 124
-
(2012)
Nature
, vol.491
, pp. 119-124
-
-
Jostins, L.1
Ripke, S.2
Weersma, R.K.3
Duerr, R.H.4
McGovern, D.5
Phui, K.Y.6
Lee, J.C.7
Schumm, L.P.8
Sharma, Y.9
Anderson, C.A.10
Essers, J.11
Mitrovic, M.12
Ning, K.13
Cleynen, I.14
Theatre, E.15
Spain, S.L.16
Raychaudhuri, S.17
Goyette, P.18
Wei, Z.19
Abraham, C.20
Achkar, J.P.21
Ahmad, T.22
Amininejad, L.23
Ananthakrishnan, A.N.24
Andersen, V.25
Andrews, J.M.26
Baidoo, L.27
Balschun, T.28
Bampton, P.A.29
Bitton, A.30
Boucher, G.31
Brand, S.32
Buning, C.33
Cohain, A.34
Cichon, S.35
D'Amato, M.36
De Jong, D.37
Devaney, K.L.38
Dubinsky, M.39
Edwards, C.40
Ellinghaus, D.41
Ferguson, L.R.42
Franchimont, D.43
Fransen, K.44
Gearry, R.45
Georges, M.46
Gieger, C.47
Glas, J.48
Haritunians, T.49
Hart, A.50
Hawkey, C.51
Hedl, M.52
Hu, X.53
Karlsen, T.H.54
Kupcinskas, L.55
Kugathasan, S.56
Latiano, A.57
Laukens, D.58
Lawrance, I.C.59
Lees, C.W.60
Louis, E.61
Mahy, G.62
Mansfield, J.63
Morgan, A.R.64
Mowat, C.65
Newman, W.66
Palmieri, O.67
Ponsioen, C.Y.68
Potocnik, U.69
Prescott, N.J.70
Regueiro, M.71
Rotter, J.I.72
Russell, R.K.73
Sanderson, J.D.74
Sans, M.75
Satsangi, J.76
Schreiber, S.77
Simms, L.A.78
Sventoraityte, J.79
Targan, S.R.80
Taylor, K.D.81
Tremelling, M.82
Verspaget, H.W.83
De Vos, M.84
Wijmenga, C.85
Wilson, D.C.86
Winkelmann, J.87
Xavier, R.J.88
Zeissig, S.89
Zhang, B.90
Zhang, C.K.91
Zhao, H.92
International, I.B.D.G.C.93
Silverberg, M.S.94
Annese, V.95
Hakonarson, H.96
Brant, S.R.97
Radford-Smith, G.98
more..
-
109
-
-
79959216005
-
Genetics and pathogenesis of inflammatory bowel disease
-
B. Khor, A. Gardet, and R.J. Xavier Genetics and pathogenesis of inflammatory bowel disease Nature 474 2011 307 317
-
(2011)
Nature
, vol.474
, pp. 307-317
-
-
Khor, B.1
Gardet, A.2
Xavier, R.J.3
-
111
-
-
84883858159
-
Intraluminal containment of commensal outgrowth in the gut during infection-induced dysbiosis
-
M.J. Molloy, J.R. Grainger, N. Bouladoux, T.W. Hand, L.Y. Koo, S. Naik, M. Quinones, A.K. Dzutsev, J.L. Gao, G. Trinchieri, P.M. Murphy, and Y. Belkaid Intraluminal containment of commensal outgrowth in the gut during infection-induced dysbiosis Cell Host Microbe 14 2013 318 328
-
(2013)
Cell Host Microbe
, vol.14
, pp. 318-328
-
-
Molloy, M.J.1
Grainger, J.R.2
Bouladoux, N.3
Hand, T.W.4
Koo, L.Y.5
Naik, S.6
Quinones, M.7
Dzutsev, A.K.8
Gao, J.L.9
Trinchieri, G.10
Murphy, P.M.11
Belkaid, Y.12
-
112
-
-
84859399981
-
Microbial translocation across the GI tract
-
J.M. Brenchley, and D.C. Douek Microbial translocation across the GI tract Annu. Rev. Immunol. 30 2012 149 173
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 149-173
-
-
Brenchley, J.M.1
Douek, D.C.2
-
113
-
-
84872688583
-
Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-gamma-dependent elimination of Paneth cells
-
M. Raetz, S.H. Hwang, C.L. Wilhelm, D. Kirkland, A. Benson, C.R. Sturge, J. Mirpuri, S. Vaishnava, B. Hou, A.L. Defranco, C.J. Gilpin, L.V. Hooper, and F. Yarovinsky Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-gamma-dependent elimination of Paneth cells Nat. Immunol. 14 2013 136 142
-
(2013)
Nat. Immunol.
, vol.14
, pp. 136-142
-
-
Raetz, M.1
Hwang, S.H.2
Wilhelm, C.L.3
Kirkland, D.4
Benson, A.5
Sturge, C.R.6
Mirpuri, J.7
Vaishnava, S.8
Hou, B.9
Defranco, A.L.10
Gilpin, C.J.11
Hooper, L.V.12
Yarovinsky, F.13
-
114
-
-
84873513423
-
Host-derived nitrate boosts growth of E. Coli in the inflamed gut
-
S.E. Winter, M.G. Winter, M.N. Xavier, P. Thiennimitr, V. Poon, A.M. Keestra, R.C. Laughlin, G. Gomez, J. Wu, S.D. Lawhon, I.E. Popova, S.J. Parikh, L.G. Adams, R.M. Tsolis, V.J. Stewart, and A.J. Baumler Host-derived nitrate boosts growth of E. coli in the inflamed gut Science 339 2013 708 711
-
(2013)
Science
, vol.339
, pp. 708-711
-
-
Winter, S.E.1
Winter, M.G.2
Xavier, M.N.3
Thiennimitr, P.4
Poon, V.5
Keestra, A.M.6
Laughlin, R.C.7
Gomez, G.8
Wu, J.9
Lawhon, S.D.10
Popova, I.E.11
Parikh, S.J.12
Adams, L.G.13
Tsolis, R.M.14
Stewart, V.J.15
Baumler, A.J.16
-
115
-
-
84878597238
-
Effector and memory T cell responses to commensal bacteria
-
Y. Belkaid, N. Bouladoux, and T.W. Hand Effector and memory T cell responses to commensal bacteria Trends Immunol. 34 2013 299 306
-
(2013)
Trends Immunol.
, vol.34
, pp. 299-306
-
-
Belkaid, Y.1
Bouladoux, N.2
Hand, T.W.3
-
116
-
-
33644839539
-
Diarrhea in American infants and young children in the community setting: Incidence, clinical presentation and microbiology
-
L. Vernacchio, R.M. Vezina, A.A. Mitchell, S.M. Lesko, A.G. Plaut, and D.W. Acheson Diarrhea in American infants and young children in the community setting: incidence, clinical presentation and microbiology Pediatr. Infect. Dis. J. 25 2006 2 7
-
(2006)
Pediatr. Infect. Dis. J.
, vol.25
, pp. 2-7
-
-
Vernacchio, L.1
Vezina, R.M.2
Mitchell, A.A.3
Lesko, S.M.4
Plaut, A.G.5
Acheson, D.W.6
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