Parasite-induced T H 1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells

Nature Immunology

Volumn 14, Issue 2, 2013, Pages 136-142

  Raetz, Megan ^a   Hwang, Sun Hee ^a   Wilhelm, Cara L ^a   Kirkland, Donna ^a   Benson, Alicia ^a   Sturge, Carolyn R ^a   Mirpuri, Julie ^a   Vaishnava, Shipra ^a   Hou, Baidong ^b,c   Defranco, Anthony L ^b   Gilpin, Christopher J ^a   Hooper, Lora V ^a,d   Yarovinsky, Felix ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c INSTITUTE OF BIOPHYSICS   (China)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; MYELOID DIFFERENTIATION FACTOR 88; POLYPEPTIDE ANTIBIOTIC AGENT; TOLL LIKE RECEPTOR 11; ALPHA DEFENSIN; INTERLEUKIN 12; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CELL DEATH; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENTEROBACTERIACEAE; GASTROINTESTINAL DISEASE; INTESTINE FLORA; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PANETH CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; REPOLARIZATION; SIGNAL TRANSDUCTION; TH1 CELL; TOXOPLASMA GONDII; TOXOPLASMOSIS; ANIMAL; ENTEROBACTERIACEAE INFECTION; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HOST PARASITE INTERACTION; HOST PATHOGEN INTERACTION; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MICROBIOLOGY; PARASITOLOGY; PATHOLOGY; TOXOPLASMA; TRANSGENIC MOUSE;

ALPHA-DEFENSINS; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL DEATH; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; GENE EXPRESSION REGULATION; HOST-PARASITE INTERACTIONS; HOST-PATHOGEN INTERACTIONS; INTERFERON-GAMMA; INTERLEUKIN-12; LYMPHOCYTE ACTIVATION; MICE; MICE, TRANSGENIC; PANETH CELLS; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; TH1 CELLS; TOXOPLASMA; TOXOPLASMOSIS, ANIMAL;

MLCS; MLOWN;

EID: 84872688583     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2508     Document Type: Article

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