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Volumn 10, Issue 10, 2014, Pages

The DAF-16 FOXO Transcription Factor Regulates natc-1 to Modulate Stress Resistance in Caenorhabditis elegans, Linking Insulin/IGF-1 Signaling to Protein N-Terminal Acetylation

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; MESSENGER RNA; METAL; SOMATOMEDIN; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR FOXO; CAENORHABDITIS ELEGANS PROTEIN; DAF-16 PROTEIN, C ELEGANS; FORKHEAD TRANSCRIPTION FACTOR; INSULIN; NATC-1 PROTEIN, C ELEGANS; PEPTIDE ALPHA N ACETYLTRANSFERASE C; SOMATOMEDIN C; ZINC;

EID: 84908325353     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004703     Document Type: Article
Times cited : (34)

References (90)
  • 1
    • 38449105152 scopus 로고    scopus 로고
    • Dauer
    • Hu PJ, (2007) Dauer. WormBook 1–19 doi:10.1895/wormbook.1.144.1
    • (2007) WormBook , pp. 1-19
    • Hu, P.J.1
  • 2
    • 0035978884 scopus 로고    scopus 로고
    • Insulin-like signaling, metabolism, stress resistance and aging in Caenorhabditis elegans
    • Braeckman BP, Houthoofd K, Vanfleteren JR, (2001) Insulin-like signaling, metabolism, stress resistance and aging in Caenorhabditis elegans. Mech Ageing Dev 122: 673–693.
    • (2001) Mech Ageing Dev , vol.122 , pp. 673-693
    • Braeckman, B.P.1    Houthoofd, K.2    Vanfleteren, J.R.3
  • 3
    • 0030813398 scopus 로고    scopus 로고
    • daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
    • Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G, (1997) daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277: 942–946 doi:10.1126/science.277.5328.942
    • (1997) Science , vol.277 , pp. 942-946
    • Kimura, K.D.1    Tissenbaum, H.A.2    Liu, Y.3    Ruvkun, G.4
  • 4
    • 0029768753 scopus 로고    scopus 로고
    • A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
    • Morris JZ, Tissenbaum HA, Ruvkun G, (1996) A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans. Nature 382: 536–539 doi:10.1038/382536a0
    • (1996) Nature , vol.382 , pp. 536-539
    • Morris, J.Z.1    Tissenbaum, H.A.2    Ruvkun, G.3
  • 5
    • 0032782364 scopus 로고    scopus 로고
    • The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans
    • Honda Y, Honda S, (1999) The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. FASEB J 13: 1385–1393.
    • (1999) FASEB J , vol.13 , pp. 1385-1393
    • Honda, Y.1    Honda, S.2
  • 6
    • 0019496482 scopus 로고
    • Interacting genes in nematode dauer larva formation
    • Riddle DL, Swanson MM, Albert PS, (1981) Interacting genes in nematode dauer larva formation. Nature 290: 668–671.
    • (1981) Nature , vol.290 , pp. 668-671
    • Riddle, D.L.1    Swanson, M.M.2    Albert, P.S.3
  • 7
    • 0030657540 scopus 로고    scopus 로고
    • daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
    • Lin K, Dorman JB, Rodan A, Kenyon C, (1997) daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278: 1319–1322.
    • (1997) Science , vol.278 , pp. 1319-1322
    • Lin, K.1    Dorman, J.B.2    Rodan, A.3    Kenyon, C.4
  • 8
    • 0030659557 scopus 로고    scopus 로고
    • The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
    • Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, et al. (1997) The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389: 994–999 doi:10.1038/40194
    • (1997) Nature , vol.389 , pp. 994-999
    • Ogg, S.1    Paradis, S.2    Gottlieb, S.3    Patterson, G.I.4    Lee, L.5
  • 9
    • 33751430460 scopus 로고    scopus 로고
    • The search for DAF-16/FOXO transcriptional targets: Approaches and discoveries
    • Murphy CT, (2006) The search for DAF-16/FOXO transcriptional targets: Approaches and discoveries. Exp Gerontol 41: 910–921 doi:10.1016/j.exger.2006.06.040
    • (2006) Exp Gerontol , vol.41 , pp. 910-921
    • Murphy, C.T.1
  • 10
    • 0035861993 scopus 로고    scopus 로고
    • DAF-16-dependent and independent expression targets of DAF-2 insulin receptor-like pathway in Caenorhabditis elegans include FKBPs
    • Yu H, Larsen PL, (2001) DAF-16-dependent and independent expression targets of DAF-2 insulin receptor-like pathway in Caenorhabditis elegans include FKBPs. Journal of Molecular Biology 314: 1017–1028 doi:10.1006/jmbi.2000.5210
    • (2001) Journal of Molecular Biology , vol.314 , pp. 1017-1028
    • Yu, H.1    Larsen, P.L.2
  • 11
    • 0037466652 scopus 로고    scopus 로고
    • DAF-16 target genes that control C. elegans life-span and metabolism
    • Lee SS, Kennedy S, Tolonen AC, Ruvkun G, (2003) DAF-16 target genes that control C. elegans life-span and metabolism. Science 300: 644–647 doi:10.1126/science.1083614
    • (2003) Science , vol.300 , pp. 644-647
    • Lee, S.S.1    Kennedy, S.2    Tolonen, A.C.3    Ruvkun, G.4
  • 12
    • 0037418579 scopus 로고    scopus 로고
    • Identification of a DAF-16 transcriptional target gene, scl-1, that regulates longevity and stress resistance in Caenorhabditis elegans
    • Ookuma S, Fukuda M, Nishida E, (2003) Identification of a DAF-16 transcriptional target gene, scl-1, that regulates longevity and stress resistance in Caenorhabditis elegans. Curr Biol 13: 427–431.
    • (2003) Curr Biol , vol.13 , pp. 427-431
    • Ookuma, S.1    Fukuda, M.2    Nishida, E.3
  • 13
    • 0042631524 scopus 로고    scopus 로고
    • Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16
    • McElwee J, Bubb K, Thomas JH, (2003) Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16. Aging Cell 2: 111–121.
    • (2003) Aging Cell , vol.2 , pp. 111-121
    • McElwee, J.1    Bubb, K.2    Thomas, J.H.3
  • 14
    • 0042092531 scopus 로고    scopus 로고
    • Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
    • Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, et al. (2003) Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424: 277–283 doi:10.1038/nature01789
    • (2003) Nature , vol.424 , pp. 277-283
    • Murphy, C.T.1    McCarroll, S.A.2    Bargmann, C.I.3    Fraser, A.4    Kamath, R.S.5
  • 15
    • 31744438846 scopus 로고    scopus 로고
    • Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation
    • Wook Oh S, Mukhopadhyay A, Dixit BL, Raha T, Green MR, et al. (2005) Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation. Nat Genet 38: 251–257 doi:10.1038/ng1723
    • (2005) Nat Genet , vol.38 , pp. 251-257
    • Wook Oh, S.1    Mukhopadhyay, A.2    Dixit, B.L.3    Raha, T.4    Green, M.R.5
  • 16
    • 46749114798 scopus 로고    scopus 로고
    • Identification of Direct Target Genes Using Joint Sequence and Expression Likelihood with Application to DAF-16
    • Yu RX, Liu J, True N, Wang W, (2008) Identification of Direct Target Genes Using Joint Sequence and Expression Likelihood with Application to DAF-16. PLoS ONE 3: e1821 doi:10.1371/journal.pone.0001821.s008
    • (2008) PLoS ONE , vol.3 , pp. e1821
    • Yu, R.X.1    Liu, J.2    True, N.3    Wang, W.4
  • 17
    • 79251488788 scopus 로고    scopus 로고
    • RNAi screen of DAF-16/FOXO target genes in C. elegans links pathogenesis and dauer formation
    • Jensen VL, Simonsen KT, Lee Y-H, Park D, Riddle DL, (2010) RNAi screen of DAF-16/FOXO target genes in C. elegans links pathogenesis and dauer formation. PLoS ONE 5: e15902 doi:10.1371/journal.pone.0015902
    • (2010) PLoS ONE , vol.5 , pp. e15902
    • Jensen, V.L.1    Simonsen, K.T.2    Lee, Y.-H.3    Park, D.4    Riddle, D.L.5
  • 19
    • 0036584593 scopus 로고    scopus 로고
    • Genetic analysis of insulin signaling in Drosophila
    • Garofalo RS, (2002) Genetic analysis of insulin signaling in Drosophila. Trends Endocrinol Metab 13: 156–162.
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 156-162
    • Garofalo, R.S.1
  • 20
    • 0036787607 scopus 로고    scopus 로고
    • Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1
    • Nakae J, Biggs WH, Kitamura T, Cavenee WK, Wright CVE, et al. (2002) Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1. Nat Genet 32: 245–253 doi:10.1038/ng890
    • (2002) Nat Genet , vol.32 , pp. 245-253
    • Nakae, J.1    Biggs, W.H.2    Kitamura, T.3    Cavenee, W.K.4    Wright, C.V.E.5
  • 21
    • 0347664057 scopus 로고    scopus 로고
    • IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
    • Holzenberger M, Dupont J, Ducos B, Leneuve P, Géloën A, et al. (2003) IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 421: 182–187 doi:10.1038/nature01298
    • (2003) Nature , vol.421 , pp. 182-187
    • Holzenberger, M.1    Dupont, J.2    Ducos, B.3    Leneuve, P.4    Géloën, A.5
  • 22
    • 0037942739 scopus 로고    scopus 로고
    • Extended longevity in mice lacking the insulin receptor in adipose tissue
    • Blüher M, Kahn BB, Kahn CR, (2003) Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 299: 572–574 doi:10.1126/science.1078223
    • (2003) Science , vol.299 , pp. 572-574
    • Blüher, M.1    Kahn, B.B.2    Kahn, C.R.3
  • 24
    • 49749124150 scopus 로고    scopus 로고
    • Intracellular zinc homeostasis and zinc signaling
    • Murakami M, Hirano T, (2008) Intracellular zinc homeostasis and zinc signaling. Cancer Science 99: 1515–1522 doi:10.1111/j.1349-7006.2008.00854.x
    • (2008) Cancer Science , vol.99 , pp. 1515-1522
    • Murakami, M.1    Hirano, T.2
  • 25
    • 0027394031 scopus 로고
    • The biochemical basis of zinc physiology
    • Vallee BL, Falchuk KH, (1993) The biochemical basis of zinc physiology. Physiol Rev 73: 79–118.
    • (1993) Physiol Rev , vol.73 , pp. 79-118
    • Vallee, B.L.1    Falchuk, K.H.2
  • 26
    • 0034056797 scopus 로고    scopus 로고
    • Human zinc deficiency
    • Hambidge M, (2000) Human zinc deficiency. J Nutr 130: 1344S–9S.
    • (2000) J Nutr , vol.130 , pp. 1344S-1349S
    • Hambidge, M.1
  • 27
    • 18344381293 scopus 로고    scopus 로고
    • Zinc deficiency is associated with increased brain zinc import and LIV-1 expression and decreased ZnT-1 expression in neonatal rats
    • Chowanadisai W, Kelleher SL, Lönnerdal B, (2005) Zinc deficiency is associated with increased brain zinc import and LIV-1 expression and decreased ZnT-1 expression in neonatal rats. J Nutr 135: 1002–1007.
    • (2005) J Nutr , vol.135 , pp. 1002-1007
    • Chowanadisai, W.1    Kelleher, S.L.2    Lönnerdal, B.3
  • 28
    • 34247137277 scopus 로고    scopus 로고
    • Zinc deficiency: a special challenge
    • Hambidge KM, Krebs NF, (2007) Zinc deficiency: a special challenge. J Nutr 137: 1101–1105.
    • (2007) J Nutr , vol.137 , pp. 1101-1105
    • Hambidge, K.M.1    Krebs, N.F.2
  • 29
    • 33845809137 scopus 로고    scopus 로고
    • Acrodermatitis enteropathica and an overview of zinc metabolism
    • Maverakis E, Fung MA, Lynch PJ, Draznin M, Michael DJ, et al. (2007) Acrodermatitis enteropathica and an overview of zinc metabolism. J Am Acad Dermatol 56: 116–124 doi:10.1016/j.jaad.2006.08.015
    • (2007) J Am Acad Dermatol , vol.56 , pp. 116-124
    • Maverakis, E.1    Fung, M.A.2    Lynch, P.J.3    Draznin, M.4    Michael, D.J.5
  • 30
    • 0029777299 scopus 로고    scopus 로고
    • The role of zinc in selective neuronal death after transient global cerebral ischemia
    • Koh JY, Suh SW, Gwag BJ, He YY, Hsu CY, et al. (1996) The role of zinc in selective neuronal death after transient global cerebral ischemia. Science 272: 1013–1016.
    • (1996) Science , vol.272 , pp. 1013-1016
    • Koh, J.Y.1    Suh, S.W.2    Gwag, B.J.3    He, Y.Y.4    Hsu, C.Y.5
  • 31
    • 34648819082 scopus 로고    scopus 로고
    • Biochemistry. How cells control zinc homeostasis
    • Nies DH, (2007) Biochemistry. How cells control zinc homeostasis. Science 317: 1695–1696 doi:10.1126/science.1149048
    • (2007) Science , vol.317 , pp. 1695-1696
    • Nies, D.H.1
  • 32
    • 0037993832 scopus 로고    scopus 로고
    • Transition metal speciation in the cell: insights from the chemistry of metal ion receptors
    • Finney LA, O'Halloran TV, (2003) Transition metal speciation in the cell: insights from the chemistry of metal ion receptors. Science 300: 931–936 doi:10.1126/science.1085049
    • (2003) Science , vol.300 , pp. 931-936
    • Finney, L.A.1    O'halloran, T.V.2
  • 33
    • 0018706654 scopus 로고
    • Cadmium toxicity in the free-living nematode, Caenorhabditis elegans
    • Popham JD, Webster JM, (1979) Cadmium toxicity in the free-living nematode, Caenorhabditis elegans. Environ Res 20: 183–191.
    • (1979) Environ Res , vol.20 , pp. 183-191
    • Popham, J.D.1    Webster, J.M.2
  • 34
    • 38849085929 scopus 로고    scopus 로고
    • Nickel sulfate induces numerous defects in Caenorhabditis elegans that can also be transferred to progeny
    • Wang D, Wang Y, (2008) Nickel sulfate induces numerous defects in Caenorhabditis elegans that can also be transferred to progeny. Environ Pollut 151: 585–592 doi:10.1016/j.envpol.2007.04.003
    • (2008) Environ Pollut , vol.151 , pp. 585-592
    • Wang, D.1    Wang, Y.2
  • 35
    • 0035082093 scopus 로고    scopus 로고
    • Longevity and heavy metal resistance in daf-2 and age-1 long-lived mutants of Caenorhabditis elegans
    • Barsyte D, Lovejoy DA, Lithgow GJ, (2001) Longevity and heavy metal resistance in daf-2 and age-1 long-lived mutants of Caenorhabditis elegans. FASEB J 15: 627–634 doi:10.1096/fj.99-0966com
    • (2001) FASEB J , vol.15 , pp. 627-634
    • Barsyte, D.1    Lovejoy, D.A.2    Lithgow, G.J.3
  • 36
    • 49849084620 scopus 로고    scopus 로고
    • Identification of Mutations in Caenorhabditis elegans That Cause Resistance to High Levels of Dietary Zinc and Analysis Using a Genomewide Map of Single Nucleotide Polymorphisms Scored by Pyrosequencing
    • Bruinsma JJ, Schneider DL, Davis DE, Kornfeld K, (2008) Identification of Mutations in Caenorhabditis elegans That Cause Resistance to High Levels of Dietary Zinc and Analysis Using a Genomewide Map of Single Nucleotide Polymorphisms Scored by Pyrosequencing. Genetics 179: 811–828 doi:10.1534/genetics.107.084384
    • (2008) Genetics , vol.179 , pp. 811-828
    • Bruinsma, J.J.1    Schneider, D.L.2    Davis, D.E.3    Kornfeld, K.4
  • 37
    • 79953766071 scopus 로고    scopus 로고
    • Histidine Protects Against Zinc and Nickel Toxicity in Caenorhabditis elegans
    • Murphy JT, Bruinsma JJ, Schneider DL, Collier S, Guthrie J, et al. (2011) Histidine Protects Against Zinc and Nickel Toxicity in Caenorhabditis elegans. PLoS Genet 7: e1002013 doi:10.1371/journal.pgen.1002013.t001
    • (2011) PLoS Genet , vol.7 , pp. e1002013
    • Murphy, J.T.1    Bruinsma, J.J.2    Schneider, D.L.3    Collier, S.4    Guthrie, J.5
  • 38
    • 0029123058 scopus 로고
    • Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress
    • Lithgow GJ, White TM, Melov S, Johnson TE, (1995) Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress. Proc Natl Acad Sci USA 92: 7540–7544.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7540-7544
    • Lithgow, G.J.1    White, T.M.2    Melov, S.3    Johnson, T.E.4
  • 39
    • 0033231015 scopus 로고    scopus 로고
    • Identification and specificities of N-terminal acetyltransferases from Saccharomyces cerevisiae
    • Polevoda B, Norbeck J, Takakura H, Blomberg A, Sherman F, (1999) Identification and specificities of N-terminal acetyltransferases from Saccharomyces cerevisiae. EMBO J 18: 6155–6168 doi:10.1093/emboj/18.21.6155
    • (1999) EMBO J , vol.18 , pp. 6155-6168
    • Polevoda, B.1    Norbeck, J.2    Takakura, H.3    Blomberg, A.4    Sherman, F.5
  • 40
    • 0034711184 scopus 로고    scopus 로고
    • Nalpha -terminal acetylation of eukaryotic proteins
    • Polevoda B, Sherman F, (2000) Nalpha -terminal acetylation of eukaryotic proteins. J Biol Chem 275: 36479–36482 doi:10.1074/jbc.R000023200
    • (2000) J Biol Chem , vol.275 , pp. 36479-36482
    • Polevoda, B.1    Sherman, F.2
  • 41
    • 78650410139 scopus 로고    scopus 로고
    • Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project
    • Gerstein MB, Lu ZJ, Van Nostrand EL, Cheng C, Arshinoff BI, et al. (2010) Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project. Science 330: 1775–1787 doi:10.1126/science.1196914
    • (2010) Science , vol.330 , pp. 1775-1787
    • Gerstein, M.B.1    Lu, Z.J.2    Van Nostrand, E.L.3    Cheng, C.4    Arshinoff, B.I.5
  • 42
    • 84877309346 scopus 로고    scopus 로고
    • DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity
    • Riedel CG, Dowen RH, Lourenco GF, Kirienko NV, Heimbucher T, et al. (2013) DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity. Nat Cell Biol 15: 491–501 doi:10.1038/ncb2720
    • (2013) Nat Cell Biol , vol.15 , pp. 491-501
    • Riedel, C.G.1    Dowen, R.H.2    Lourenco, G.F.3    Kirienko, N.V.4    Heimbucher, T.5
  • 43
    • 48949116611 scopus 로고    scopus 로고
    • Towards a mutation in every gene in Caenorhabditis elegans
    • Moerman DG, Barstead RJ, (2008) Towards a mutation in every gene in Caenorhabditis elegans. Brief Funct Genomic Proteomic 7: 195–204 doi:10.1093/bfgp/eln016
    • (2008) Brief Funct Genomic Proteomic , vol.7 , pp. 195-204
    • Moerman, D.G.1    Barstead, R.J.2
  • 44
    • 0035827594 scopus 로고    scopus 로고
    • NatC Nalpha-terminal acetyltransferase of yeast contains three subunits, Mak3p, Mak10p, and Mak31p
    • Polevoda B, Sherman F, (2001) NatC Nalpha-terminal acetyltransferase of yeast contains three subunits, Mak3p, Mak10p, and Mak31p. J Biol Chem 276: 20154–20159 doi:10.1074/jbc.M011440200
    • (2001) J Biol Chem , vol.276 , pp. 20154-20159
    • Polevoda, B.1    Sherman, F.2
  • 46
    • 38149092669 scopus 로고    scopus 로고
    • Proteasomal dysfunction activates the transcription factor SKN-1 and produces a selective oxidative-stress response in Caenorhabditis elegans
    • Kahn NW, Rea SL, Moyle S, Kell A, Johnson TE, (2008) Proteasomal dysfunction activates the transcription factor SKN-1 and produces a selective oxidative-stress response in Caenorhabditis elegans. Biochem J 409: 205–213 doi:10.1042/BJ20070521
    • (2008) Biochem J , vol.409 , pp. 205-213
    • Kahn, N.W.1    Rea, S.L.2    Moyle, S.3    Kell, A.4    Johnson, T.E.5
  • 47
    • 0034967720 scopus 로고    scopus 로고
    • Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
    • Lin K, Hsin H, Libina N, Kenyon C, (2001) Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nat Genet 28: 139–145 doi:10.1038/88850
    • (2001) Nat Genet , vol.28 , pp. 139-145
    • Lin, K.1    Hsin, H.2    Libina, N.3    Kenyon, C.4
  • 48
    • 0035846601 scopus 로고    scopus 로고
    • Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway
    • Lee RY, Hench J, Ruvkun G, (2001) Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway. Curr Biol 11: 1950–1957.
    • (2001) Curr Biol , vol.11 , pp. 1950-1957
    • Lee, R.Y.1    Hench, J.2    Ruvkun, G.3
  • 49
    • 0028280285 scopus 로고
    • A screen for nonconditional dauer-constitutive mutations in Caenorhabditis elegans
    • Malone EA, Thomas JH, (1994) A screen for nonconditional dauer-constitutive mutations in Caenorhabditis elegans. Genetics 136: 879–886.
    • (1994) Genetics , vol.136 , pp. 879-886
    • Malone, E.A.1    Thomas, J.H.2
  • 50
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild type
    • Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R, (1993) A C. elegans mutant that lives twice as long as wild type. Nature 366: 461–464 doi:10.1038/366461a0
    • (1993) Nature , vol.366 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 51
    • 0030014296 scopus 로고    scopus 로고
    • A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans
    • Murakami S, Johnson TE, (1996) A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans. Genetics 143: 1207–1218.
    • (1996) Genetics , vol.143 , pp. 1207-1218
    • Murakami, S.1    Johnson, T.E.2
  • 52
    • 0037274713 scopus 로고    scopus 로고
    • Positive selection of Caenorhabditis elegans mutants with increased stress resistance and longevity
    • Muñoz MJ, Riddle DL, (2003) Positive selection of Caenorhabditis elegans mutants with increased stress resistance and longevity. Genetics 163: 171–180.
    • (2003) Genetics , vol.163 , pp. 171-180
    • Muñoz, M.J.1    Riddle, D.L.2
  • 53
    • 77649225979 scopus 로고    scopus 로고
    • Genome-Wide Identification of Binding Sites Defines Distinct Functions for Caenorhabditis elegans PHA-4/FOXA in Development and Environmental Response
    • Zhong M, Niu W, Lu ZJ, Sarov M, Murray JI, et al. (2010) Genome-Wide Identification of Binding Sites Defines Distinct Functions for Caenorhabditis elegans PHA-4/FOXA in Development and Environmental Response. PLoS Genet 6: e1000848 doi:10.1371/journal.pgen.1000848.s017
    • (2010) PLoS Genet , vol.6 , pp. e1000848
    • Zhong, M.1    Niu, W.2    Lu, Z.J.3    Sarov, M.4    Murray, J.I.5
  • 54
    • 0030667197 scopus 로고    scopus 로고
    • Cloning, expression, and characterization of two manganese superoxide dismutases from Caenorhabditis elegans
    • Hunter T, Bannister WH, Hunter GJ, (1997) Cloning, expression, and characterization of two manganese superoxide dismutases from Caenorhabditis elegans. J Biol Chem 272: 28652–28659 doi:10.1074/jbc.272.45.28652
    • (1997) J Biol Chem , vol.272 , pp. 28652-28659
    • Hunter, T.1    Bannister, W.H.2    Hunter, G.J.3
  • 55
    • 0345447590 scopus 로고    scopus 로고
    • Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan
    • Libina N, Berman JR, Kenyon C, (2003) Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan. Cell 115: 489–502.
    • (2003) Cell , vol.115 , pp. 489-502
    • Libina, N.1    Berman, J.R.2    Kenyon, C.3
  • 56
    • 79960946480 scopus 로고    scopus 로고
    • NatF Contributes to an Evolutionary Shift in Protein N-Terminal Acetylation and Is Important for Normal Chromosome Segregation
    • Van Damme P, Hole K, Pimenta-Marques A, Helsens K, Vandekerckhove J, et al. (2011) NatF Contributes to an Evolutionary Shift in Protein N-Terminal Acetylation and Is Important for Normal Chromosome Segregation. PLoS Genet 7: e1002169 doi:10.1371/journal.pgen.1002169.t002
    • (2011) PLoS Genet , vol.7 , pp. e1002169
    • Van Damme, P.1    Hole, K.2    Pimenta-Marques, A.3    Helsens, K.4    Vandekerckhove, J.5
  • 57
    • 84859490749 scopus 로고    scopus 로고
    • Protein N-terminal acetyltransferases: when the start matters
    • Starheim KK, Gevaert K, Arnesen T, (2012) Protein N-terminal acetyltransferases: when the start matters. Trends Biochem Sci 37: 152–161 doi:10.1016/j.tibs.2012.02.003
    • (2012) Trends Biochem Sci , vol.37 , pp. 152-161
    • Starheim, K.K.1    Gevaert, K.2    Arnesen, T.3
  • 58
    • 80051550297 scopus 로고    scopus 로고
    • Using VAAST to identify an X-linked disorder resulting in lethality in male infants due to N-terminal acetyltransferase deficiency
    • Rope AF, Wang K, Evjenth R, Xing J, Johnston JJ, et al. (2011) Using VAAST to identify an X-linked disorder resulting in lethality in male infants due to N-terminal acetyltransferase deficiency. Am J Hum Genet 89: 28–43 doi:10.1016/j.ajhg.2011.05.017
    • (2011) Am J Hum Genet , vol.89 , pp. 28-43
    • Rope, A.F.1    Wang, K.2    Evjenth, R.3    Xing, J.4    Johnston, J.J.5
  • 59
    • 0034628508 scopus 로고    scopus 로고
    • A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae
    • Uetz PP, Giot LL, Cagney GG, Mansfield TAT, Judson RSR, et al. (2000) A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403: 623–627 doi:10.1038/35001009
    • (2000) Nature , vol.403 , pp. 623-627
    • Uetz, P.P.1    Giot, L.L.2    Cagney, G.G.3    Mansfield, T.A.T.4    Judson, R.S.R.5
  • 60
    • 0032828715 scopus 로고    scopus 로고
    • A generic protein purification method for protein complex characterization and proteome exploration
    • Rigaut G, Shevchenko A, Rutz B, Wilm M, Mann M, et al. (1999) A generic protein purification method for protein complex characterization and proteome exploration. Nat Biotechnol 17: 1030–1032 doi:10.1038/13732
    • (1999) Nat Biotechnol , vol.17 , pp. 1030-1032
    • Rigaut, G.1    Shevchenko, A.2    Rutz, B.3    Wilm, M.4    Mann, M.5
  • 61
    • 0026757389 scopus 로고
    • MAK10, a glucose-repressible gene necessary for replication of a dsRNA virus of Saccharomyces cerevisiae, has T cell receptor alpha-subunit motifs
    • Lee YJ, Wickner RB, (1992) MAK10, a glucose-repressible gene necessary for replication of a dsRNA virus of Saccharomyces cerevisiae, has T cell receptor alpha-subunit motifs. Genetics 132: 87–96.
    • (1992) Genetics , vol.132 , pp. 87-96
    • Lee, Y.J.1    Wickner, R.B.2
  • 62
    • 0026744480 scopus 로고
    • MAK3 encodes an N-acetyltransferase whose modification of the L-A gag NH2 terminus is necessary for virus particle assembly
    • Tercero JC, Wickner RB, (1992) MAK3 encodes an N-acetyltransferase whose modification of the L-A gag NH2 terminus is necessary for virus particle assembly. J Biol Chem 267: 20277–20281.
    • (1992) J Biol Chem , vol.267 , pp. 20277-20281
    • Tercero, J.C.1    Wickner, R.B.2
  • 63
    • 0041920603 scopus 로고    scopus 로고
    • Cytoplasmic N-terminal protein acetylation is required for efficient photosynthesis in Arabidopsis
    • Pesaresi P, Gardner NA, Masiero S, Dietzmann A, Eichacker L, et al. (2003) Cytoplasmic N-terminal protein acetylation is required for efficient photosynthesis in Arabidopsis. Plant Cell 15: 1817–1832.
    • (2003) Plant Cell , vol.15 , pp. 1817-1832
    • Pesaresi, P.1    Gardner, N.A.2    Masiero, S.3    Dietzmann, A.4    Eichacker, L.5
  • 64
    • 33645734898 scopus 로고    scopus 로고
    • Embryonic growth-associated protein is one subunit of a novel N-terminal acetyltransferase complex essential for embryonic vascular development
    • Wenzlau JM, Garl PJ, Simpson P, Stenmark KR, West J, et al. (2006) Embryonic growth-associated protein is one subunit of a novel N-terminal acetyltransferase complex essential for embryonic vascular development. Circ Res 98: 846–855 doi:10.1161/01.RES.0000214539.86593.7a
    • (2006) Circ Res , vol.98 , pp. 846-855
    • Wenzlau, J.M.1    Garl, P.J.2    Simpson, P.3    Stenmark, K.R.4    West, J.5
  • 65
    • 0033859750 scopus 로고    scopus 로고
    • A novel epithelial wound-related gene is abundantly expressed in developing rat cornea and skin
    • Yi XJ, Li XF, Yu FS, (2000) A novel epithelial wound-related gene is abundantly expressed in developing rat cornea and skin. Curr Eye Res 20: 430–440.
    • (2000) Curr Eye Res , vol.20 , pp. 430-440
    • Yi, X.J.1    Li, X.F.2    Yu, F.S.3
  • 66
    • 67650085001 scopus 로고    scopus 로고
    • Knockdown of Human N -Terminal Acetyltransferase Complex C Leads to p53-Dependent Apoptosis and Aberrant Human Arl8b Localization
    • Starheim KK, Gromyko D, Evjenth R, Ryningen A, Varhaug JE, et al. (2009) Knockdown of Human N -Terminal Acetyltransferase Complex C Leads to p53-Dependent Apoptosis and Aberrant Human Arl8b Localization. Mol Cell Biol 29: 3569–3581 doi:10.1128/MCB.01909-08
    • (2009) Mol Cell Biol , vol.29 , pp. 3569-3581
    • Starheim, K.K.1    Gromyko, D.2    Evjenth, R.3    Ryningen, A.4    Varhaug, J.E.5
  • 67
    • 0036102081 scopus 로고    scopus 로고
    • Zinc ions and cation diffusion facilitator proteins regulate Ras-mediated signaling
    • Bruinsma JJ, Jirakulaporn T, Muslin AJ, Kornfeld K, (2002) Zinc ions and cation diffusion facilitator proteins regulate Ras-mediated signaling. Dev Cell 2: 567–578.
    • (2002) Dev Cell , vol.2 , pp. 567-578
    • Bruinsma, J.J.1    Jirakulaporn, T.2    Muslin, A.J.3    Kornfeld, K.4
  • 68
    • 0842328578 scopus 로고    scopus 로고
    • Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase
    • Yoder JH, Chong H, Guan K-L, Han M, (2004) Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase. EMBO J 23: 111–119 doi:10.1038/sj.emboj.7600025
    • (2004) EMBO J , vol.23 , pp. 111-119
    • Yoder, J.H.1    Chong, H.2    Guan, K.-L.3    Han, M.4
  • 69
    • 84855471897 scopus 로고    scopus 로고
    • Lysosome-related organelles in intestinal cells are a zinc storage site in C. elegans
    • Roh HC, Collier S, Guthrie J, Robertson JD, Kornfeld K, (2012) Lysosome-related organelles in intestinal cells are a zinc storage site in C. elegans. Cell Metab 15: 88–99 doi:10.1016/j.cmet.2011.12.003
    • (2012) Cell Metab , vol.15 , pp. 88-99
    • Roh, H.C.1    Collier, S.2    Guthrie, J.3    Robertson, J.D.4    Kornfeld, K.5
  • 70
    • 84878483205 scopus 로고    scopus 로고
    • ttm-1 Encodes CDF Transporters That Excrete Zinc from Intestinal Cells of C. elegans and Act in a Parallel Negative Feedback Circuit That Promotes Homeostasis
    • Roh HC, Collier S, Deshmukh K, Guthrie J, Robertson JD, et al. (2013) ttm-1 Encodes CDF Transporters That Excrete Zinc from Intestinal Cells of C. elegans and Act in a Parallel Negative Feedback Circuit That Promotes Homeostasis. PLoS Genet 9: e1003522 doi:10.1371/journal.pgen.1003522.s004
    • (2013) PLoS Genet , vol.9 , pp. e1003522
    • Roh, H.C.1    Collier, S.2    Deshmukh, K.3    Guthrie, J.4    Robertson, J.D.5
  • 71
    • 77952729079 scopus 로고    scopus 로고
    • The two Caenorhabditis elegans metallothioneins (CeMT-1 and CeMT-2) discriminate between essential zinc and toxic cadmium
    • Zeitoun-Ghandour S, Charnock JM, Hodson ME, Leszczyszyn OI, Blindauer CA, et al. (2010) The two Caenorhabditis elegans metallothioneins (CeMT-1 and CeMT-2) discriminate between essential zinc and toxic cadmium. FEBS Journal 277: 2531–2542 doi:10.1111/j.1742-4658.2010.07667.x
    • (2010) FEBS Journal , vol.277 , pp. 2531-2542
    • Zeitoun-Ghandour, S.1    Charnock, J.M.2    Hodson, M.E.3    Leszczyszyn, O.I.4    Blindauer, C.A.5
  • 72
    • 0032514466 scopus 로고    scopus 로고
    • A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes
    • Ishii N, Fujii M, Hartman PS, Tsuda M, Yasuda K, et al. (1998) A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes. Nature 394: 694–697 doi:10.1038/29331
    • (1998) Nature , vol.394 , pp. 694-697
    • Ishii, N.1    Fujii, M.2    Hartman, P.S.3    Tsuda, M.4    Yasuda, K.5
  • 73
    • 30744458144 scopus 로고    scopus 로고
    • Reduction of Caenorhabditis elegans frataxin increases sensitivity to oxidative stress, reduces lifespan, and causes lethality in a mitochondrial complex II mutant
    • Vázquez-Manrique RP, González-Cabo P, Ros S, Aziz H, Baylis HA, et al. (2006) Reduction of Caenorhabditis elegans frataxin increases sensitivity to oxidative stress, reduces lifespan, and causes lethality in a mitochondrial complex II mutant. The FASEB Journal 20: 172–174 doi:10.1096/fj.05-4212fje
    • (2006) The FASEB Journal , vol.20 , pp. 172-174
    • Vázquez-Manrique, R.P.1    González-Cabo, P.2    Ros, S.3    Aziz, H.4    Baylis, H.A.5
  • 74
    • 50049116926 scopus 로고    scopus 로고
    • C. elegans dauer formation and the molecular basis of plasticity
    • Fielenbach N, Antebi A, (2008) C. elegans dauer formation and the molecular basis of plasticity. Genes Dev 22: 2149–2165 doi:10.1101/gad.1701508
    • (2008) Genes Dev , vol.22 , pp. 2149-2165
    • Fielenbach, N.1    Antebi, A.2
  • 75
    • 33645527191 scopus 로고    scopus 로고
    • Hormonal control of C. elegans dauer formation and life span by a Rieske-like oxygenase
    • Rottiers V, Motola DL, Gerisch B, Cummins CL, Nishiwaki K, et al. (2006) Hormonal control of C. elegans dauer formation and life span by a Rieske-like oxygenase. Dev Cell 10: 473–482 doi:10.1016/j.devcel.2006.02.008
    • (2006) Dev Cell , vol.10 , pp. 473-482
    • Rottiers, V.1    Motola, D.L.2    Gerisch, B.3    Cummins, C.L.4    Nishiwaki, K.5
  • 76
    • 0001052838 scopus 로고
    • Evidence for the existence of three primary strategies in plants and its relevance to ecological and evolutionary theory
    • Grime JP (1977) Evidence for the existence of three primary strategies in plants and its relevance to ecological and evolutionary theory. American Naturalist: 1169–1194.
    • (1977) American Naturalist , pp. 1169-1194
    • Grime, J.P.1
  • 78
    • 0021032459 scopus 로고
    • Carbon/nutrient balance of boreal plants in relation to vertebrate herbivory
    • Bryant JP, Chapin FS, IIIKlein DR, (1983) Carbon/nutrient balance of boreal plants in relation to vertebrate herbivory. Oikos 357–368.
    • (1983) Oikos , pp. 357-368
    • Bryant, J.P.1    Chapin, F.S.2    Klein, D.R.3
  • 79
    • 0027800162 scopus 로고
    • Evolution of suites of traits in response to environmental stress
    • Chapin FS, IIIAutumn K, Pugnaire F, (1993) Evolution of suites of traits in response to environmental stress. American Naturalist S78–S92.
    • (1993) American Naturalist , pp. S78-S92
    • Chapin, F.S.1    Autumn, K.2    Pugnaire, F.3
  • 80
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner S, (1974) The genetics of Caenorhabditis elegans. Genetics 77: 71–94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 81
    • 0016766716 scopus 로고
    • The dauerlarva, a post-embryonic developmental variant of the nematode Caenorhabditis elegans
    • Cassada RC, Russell RL, (1975) The dauerlarva, a post-embryonic developmental variant of the nematode Caenorhabditis elegans. Dev Biol 46: 326–342.
    • (1975) Dev Biol , vol.46 , pp. 326-342
    • Cassada, R.C.1    Russell, R.L.2
  • 82
    • 0035229245 scopus 로고    scopus 로고
    • Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans
    • RESEARCH0002
    • Kamath RS, Martinez-Campos M, Zipperlen P, Fraser AG, Ahringer J, (2001) Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans. Genome Biol 2: RESEARCH0002 doi:10.1186/gb-2000-2-1-research0002
    • (2001) Genome Biol , vol.2
    • Kamath, R.S.1    Martinez-Campos, M.2    Zipperlen, P.3    Fraser, A.G.4    Ahringer, J.5
  • 83
    • 0038725897 scopus 로고    scopus 로고
    • Genome-wide RNAi screening in Caenorhabditis elegans
    • Kamath RS, Ahringer J, (2003) Genome-wide RNAi screening in Caenorhabditis elegans. Methods 30: 313–321.
    • (2003) Methods , vol.30 , pp. 313-321
    • Kamath, R.S.1    Ahringer, J.2
  • 84
    • 0025942107 scopus 로고
    • Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences
    • Mello CC, Kramer JM, Stinchcomb D, Ambros V, (1991) Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J 10: 3959–3970.
    • (1991) EMBO J , vol.10 , pp. 3959-3970
    • Mello, C.C.1    Kramer, J.M.2    Stinchcomb, D.3    Ambros, V.4
  • 85
    • 60849139395 scopus 로고    scopus 로고
    • GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists
    • Eden E, Navon R, Steinfeld I, Lipson D, Yakhini Z, (2009) GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists. BMC Bioinformatics 10: 48 doi:10.1186/1471-2105-10-48
    • (2009) BMC Bioinformatics , vol.10 , pp. 48
    • Eden, E.1    Navon, R.2    Steinfeld, I.3    Lipson, D.4    Yakhini, Z.5
  • 86
    • 70350168810 scopus 로고    scopus 로고
    • The Cation Diffusion Facilitator Gene cdf-2 Mediates Zinc Metabolism in Caenorhabditis elegans
    • Davis DE, Roh HC, Deshmukh K, Bruinsma JJ, Schneider DL, et al. (2009) The Cation Diffusion Facilitator Gene cdf-2 Mediates Zinc Metabolism in Caenorhabditis elegans. Genetics 182: 1015–1033 doi:10.1534/genetics.109.103614
    • (2009) Genetics , vol.182 , pp. 1015-1033
    • Davis, D.E.1    Roh, H.C.2    Deshmukh, K.3    Bruinsma, J.J.4    Schneider, D.L.5
  • 87
    • 44949231424 scopus 로고    scopus 로고
    • Analyzing real-time PCR data by the comparative CT method
    • Schmittgen TD, Livak KJ, (2008) Analyzing real-time PCR data by the comparative CT method. Nat Protoc 3: 1101–1108 doi:10.1038/nprot.2008.73
    • (2008) Nat Protoc , vol.3 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 88
    • 0028334880 scopus 로고
    • daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans
    • Gottlieb S, Ruvkun G, (1994) daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans. Genetics 137: 107–120.
    • (1994) Genetics , vol.137 , pp. 107-120
    • Gottlieb, S.1    Ruvkun, G.2
  • 89
    • 43649105922 scopus 로고    scopus 로고
    • Modulation of longevity and diapause by redox regulation mechanisms under the insulin-like signaling control in Caenorhabditis elegans
    • Honda Y, Tanaka M, Honda S, (2008) Modulation of longevity and diapause by redox regulation mechanisms under the insulin-like signaling control in Caenorhabditis elegans. Exp Gerontol 43: 520–529 doi:10.1016/j.exger.2008.02.009
    • (2008) Exp Gerontol , vol.43 , pp. 520-529
    • Honda, Y.1    Tanaka, M.2    Honda, S.3
  • 90
    • 0031685525 scopus 로고    scopus 로고
    • Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans
    • Gems D, Sutton AJ, Sundermeyer ML, Albert PS, King KV, et al. (1998) Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans. Genetics 150: 129–155.
    • (1998) Genetics , vol.150 , pp. 129-155
    • Gems, D.1    Sutton, A.J.2    Sundermeyer, M.L.3    Albert, P.S.4    King, K.V.5


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