Transition metal speciation in the cell: Insights from the chemistry of metal ion receptors

Science

Volumn 300, Issue 5621, 2003, Pages 931-936

  Finney, Lydia A ^a   O'Halloran, Thomas V ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; PROTEINS; SENSORS;

CYTOTOXIC REACTIONS;

TRANSITION METALS;

CARRIER PROTEIN; CELL RECEPTOR; CHAPERONE; COORDINATION COMPOUND; COPPER; METAL ION; METAL ION RECEPTOR; METALLOPROTEIN; REGULATOR PROTEIN; SOLVENT; TRANSITION ELEMENT; UNCLASSIFIED DRUG; ZINC;

ION; METAL; SPECIATION (CHEMISTRY);

ANIMAL CELL; BIOACCUMULATION; BIOSENSOR; CATALYSIS; CELL; CHEMISTRY; CYTOTOXICITY; HOMEOSTASIS; HUMAN; HUMAN CELL; INORGANIC CHEMISTRY; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW;

BACTERIA; BINDING SITES; CARRIER PROTEINS; COPPER; CYTOPLASM; HOMEOSTASIS; ION TRANSPORT; IRON; KINETICS; METALLOPROTEINS; METALS; MITOCHONDRIA; NICKEL; SACCHAROMYCES CEREVISIAE; THERMODYNAMICS; TRANSITION ELEMENTS; ZINC;

ANIMALIA;

EID: 0037993832     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1085049     Document Type: Review

References (82)

1. P. C. Bull, G. R. Thomas, J. M. Rommens, J. R. Forbes, D. W. Cox, Nature Genet. 5, 327 (1993).
2. C. Vulpe, B. Levinson, S. Whitney, S. Packman, J. Gitschier, Nature Genet. 3, 7 (1993).
3. J. F. Mercer et al., Nature Genet. 3, 20 (1993).
4. D. R. Rosen et al., Nature 362, 59 (1993).
5. T. V. O'Halloran, Science 261, 715 (1993).
6. A. Dancis et al., Cell 76, 393 (1994).
7. C. E. Outten, T. V. O'Halloran, Science 292, 2488 (2001).
8. S. Pedersen, P. L. Bloch, S. Reeh, F. C. Neidhardt, Cell 14, 179 (1978).
9. D. L. Huffman, T. V. O'Halloran, J. Biol. Chem. 275, 18611 (2000).
10. T. D. Rae, P. J. Schmidt, R. A. Pufahl, V. C. Culotta, T. V. O'Halloran, Science 284, 805 (1999).
11. Y. Hitomi, C. E. Outten, T. V. O'Halloran, J. Am. Chem. Soc. 123, 8614 (2001).
12. M. L. VanZile, N. J. Cosper, R. A. Scott, D. P. Giedroc, Biochemistry 39, 11818 (2000).
13. J. S. Cavet et al., J. Biol. Chem. 277, 38441 (2002).
14. T. V. O'Halloran, V. C. Culotta, J. Biol. Chem. 275, 25057 (2000).
15. D. L. Huffman, T. V. O'Halloran, Annu. Rev. Biochem. 70, 677 (2001).
16. S. J. Lin, V. C. Culotta, Proc. Natl. Acad. Sci. U.S.A. 92, 3784 (1995).
17. V. C. Culotta et al., J. Biol. Chem. 272, 23469 (1997).
18. S. J. Lin, R. A. Pufahl, A. Dancis, T. V. O'Halloran, V. C. Culotta, J. Biol. Chem. 272, 9215 (1997).
19. R. A. Pufahl et al., Science 278, 853 (1997).
20. Single-letter abbreviations for the amino acid residues are as follows: A, Ala; C, Cys; D, Asp; E, Glu; F, Phe; G, Gly; H, His; I, Ile; K, Lys; L, Leu; M, Met; N, Asn; P, Pro; Q, Gln; R, Arg; S, Ser; T, Thr; V, Val; W, Trp; X, any amino acid; and Y, Tyr.
21. A. C. Rosenzweig et al., Struct. Fold Des. 7, 605 (1999).
22. F. Arnesano, L. Banci, I. Bertini, D. L. Huffman, T. V. O'Halloran, Biochemistry 40, 1528 (2001).
23. J. Gitschier, B. Moffat, D. Reilly, W. I. Wood, W, J. Fairbrother, Nature Struct. Biol. 5, 47 (1998).
24. A. K. Wernimont, D. L. Huffman, A. L. Lamb, T. V. O'Halloran, A. C. Rosenzweig, Nature Struct. Biol. 7, 766 (2000).
25. L. Banci, I. Bertini, S. Ciofi-Baffoni, D. L. Huffman, T. V. O'Halloran, J. Biol. Chem. 276, 8415 (2001).
26. M. J. C. Martina Ralle, S. Lutsenko, N. J. Blackburn, J. Am. Chem. Soc. 120, 13525 (1998).
27. F. Arnesano et al., J. Biol. Chem. 276, 41365 (2001).
28. R. El Meskini, V. C. Culotta, R. E. Mains, B. A. Eipper, J. Biol. Chem. 278, 12278 (2003).
29. Z. Xiao, A. G. Wedd, Chem. Commun. 588 (2002).
30. A. C. Rosenzweig, Acc. Chem. Res. 34, 119 (2001).
31. I. Hamza, J. Prohaska, J. D. Gitlin, Proc. Natl. Acad. Sci. U.S.A. 100, 1215 (2003).
32. S. Tottey et al., J. Biol. Chem. 277, 5490 (2002).
33. S. Puig, D. J. Thiele, Curr. Opin. Chem. Biol. 6, 171 (2002).
34. F. Arnesano et al., Genome Res. 12, 255 (2002).
35. I. Bertini, A. Rosato, Proc. Natl. Acad. Sci. U.S.A. 100, 3601 (2003).
36. P. A. Cobine et al., Biochemistry 41, 5822 (2002).
37. L. Banci, I. Bertini, S. Ciofi-Baffoni, R. Del Conte, L. Gonnelli, Biochemistry 42, 1939 (2003).
38. M. D. Harrison, C. E. Jones, M. Solioz, C. T. Dameron, Trends Biochem. Sci. 25, 29 (2000).
39. P. A. Cobine, C. E. Jones, C. T. Dameron, J. Inorg. Biochem. 88, 192 (2002).
40. D. R. Winge, in press.
41. J. Beers, D. M. Glerum, A. Tzagoloff, J. Biol. Chem. 272, 33191 (1997).
42. D. N. Heaton, G. N. George, G. Garrison, D. R. Winge, Biochemistry 40, 743 (2001).
43. H. S. Carr, G. N. George, D. R. Winge, J. Biol. Chem. 277, 31237 (2002).
44. F. W. Outten, C. E. Outten, J. Hale, T. V. O'Halloran, J. Biol. Chem. 275, 31024 (2000).
45. J. V. Stoyanov, J. L. Hobman, N. L. Brown, Mol. Microbiol. 39, 502 (2001).
46. F. W. Outten, D. L. Huffman, J. A. Hale, T. V. O'Halloran, J. Biol. Chem. 276, 30670 (2001).
47. C. Rensing, B. Fan, R. Sharma, B. Mitra, B. P. Rosen, Proc. Natl. Acad. Sci. U.S.A. 97, 652 (2000).
48. S. Puig, E. Rees, D. Thiele, Structure 10, 1292 (2002).
49. S. A. Roberts et al., Proc. Natl. Acad. Sci. U.S.A. 99, 2766 (2002).
50. D. L. Huffman et al., Biochemistry 41, 10046 (2002).
51. K. Peariso, D. L. Huffman, J. E. Penner-Hahn, T. V. O'Halloran, J. Am. Chem. Soc. 125, 342 (2003).
52. S. M. Lee et al., Biochem. Biophys. Res. Commun. 295, 616 (2002).
53. A. K. Wemimont et al., Biol. Inorg. Chem. 8, 185 (2003).
54. F. Arnesano, L. Banci, I. Bertini, A. Thompsett, Structure 10, 1337 (2002).
55. F. Arnesano, L. Banci, I. Bertini, S. Mangani, A. R. Thompsett, Proc. Natl. Acad. Sci. U.S.A. 100, 3814 (2003).
56. L. Banci et al., J. Mol. Biol. 323, 883 (2002).
57. D. S. Auld, Biometals 14, 271 (2001).
58. B. Mitra, R. Sharma, Biochemistry 40, 7694 (2001).
59. Z. J. Hou, S. Narindrasorasak, B. Bhushan, B. Sarkar, B. Mitra, J. Biol. Chem. 276, 40858 (2001).
60. C. Rensing, B. Mitra, B. P. Rosen, Proc. Natl. Acad. Sci. U.S.A. 94, 14326 (1997).
61. R. Sharma, C. Rensing, B. P. Rosen, B. Mitra, J. Biol. Chem. 275, 3873 (2000).
62. J. S. Cavet, G. P. M. Borrelly, N. J. Robinson, FEMS Microbiol. Rev., in press.
63. L. A. Gaither, D. J. Eide, Biometal 14, 251 (2001).
64. G. K. Andrews, Biometal 14, 223 (2001).
65. R. J. McMahon, R. J. Cousins, J. Nutr. 128, 667 (1998).
66. H. Schulz, L. Thony-Meyer, J. Bacteriol. 182, 6831 (2000).
67. L. Thony-Meyer, Biochem. Soc. Trans. 30, 633 (2002).
68. F. Arnesano et al., Biochemistry 41, 13587 (2002).
69. P. T. Chivers, R. T. Sauer, Chem. Biol. 9, 1141 (2002).
70. J. D. Helmann, Chem. Biol. 9, 1055 (2002).
71. S. Ciurli et al., J. Biol. Inorg. Chem. 7, 623 (2002).
72. H. Remaut, N. Safarov, S. Ciurli, J. Van Beeumen, J. Biol. Chem. 276, 49365 (2001).
73. H. K. Song, S. B. Mulrooney, R. Huber, R. P. Hausinger, J. Biol. Chem. 276, 49359 (2001).
74. K. Keyer, J. A. Imlay, Proc. Natl. Acad. Sci. U.S.A. 93, 13635 (1996).
75. N. C. Andrews, Curr. Opin. Chem. Biol. 6, 181 (2002).
76. L. Li, O. S. Chen, D. McVey Ward, J. Kaplan, J. Biol. Chem. 276, 29515 (2001).
77. O. S. Chen, J. Kaplan, J. Biol. Chem. 275, 7626 (2000).
78. E. E. Luk, V. C. Culotta, J. Biol. Chem. 276, 47556 (2001).
79. D. J. Waggoner, T. B. Bartnikas, J. D. Gitlin, Neurobiol. Dis. 6, 221 (1999).
80. D. W. Choi, J. Y. Koh, Annu. Rev. Neurosci. 21, 347 (1998).
81. J. Y. Koh et al., Science 272, 1013 (1996).
82. We thank J. Wolford, H. Godwin, N. Robinson, D. Winge, and V. Culotta for helpful discussions, as well as NIGMS (T.V.O.) and the Fannie and John Hertz Foundation (L.A.F.) for financial support.