메뉴 건너뛰기




Volumn 9, Issue 5, 2013, Pages

ttm-1 Encodes CDF Transporters That Excrete Zinc from Intestinal Cells of C. elegans and Act in a Parallel Negative Feedback Circuit That Promotes Homeostasis

Author keywords

[No Author keywords available]

Indexed keywords

CATION DIFFUSION FACILITATOR; TTM 1B PROTEIN; UNCLASSIFIED DRUG; ZINC TRANSPORTER;

EID: 84878483205     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003522     Document Type: Article
Times cited : (35)

References (46)
  • 1
    • 0027394031 scopus 로고
    • The biochemical basis of zinc physiology
    • Vallee BL, Falchuk KH, (1993) The biochemical basis of zinc physiology. Physiol Rev 73: 79-118.
    • (1993) Physiol Rev , vol.73 , pp. 79-118
    • Vallee, B.L.1    Falchuk, K.H.2
  • 3
    • 49749124150 scopus 로고    scopus 로고
    • Intracellular zinc homeostasis and zinc signaling
    • Murakami M, Hirano T, (2008) Intracellular zinc homeostasis and zinc signaling. Cancer Sci 99: 1515-1522.
    • (2008) Cancer Sci , vol.99 , pp. 1515-1522
    • Murakami, M.1    Hirano, T.2
  • 4
    • 77955923038 scopus 로고    scopus 로고
    • Zinc availability regulates exit from meiosis in maturing mammalian oocytes
    • Kim AM, Vogt S, O'Halloran TV, Woodruff TK, (2010) Zinc availability regulates exit from meiosis in maturing mammalian oocytes. Nat Chem Biol 6: 674-681.
    • (2010) Nat Chem Biol , vol.6 , pp. 674-681
    • Kim, A.M.1    Vogt, S.2    O'Halloran, T.V.3    Woodruff, T.K.4
  • 5
    • 0025121927 scopus 로고
    • Zinc toxicity
    • Fosmire GJ, (1990) Zinc toxicity. Am J Clin Nutr 51: 225-227.
    • (1990) Am J Clin Nutr , vol.51 , pp. 225-227
    • Fosmire, G.J.1
  • 6
    • 0034056797 scopus 로고    scopus 로고
    • Human zinc deficiency
    • Hambidge M, (2000) Human zinc deficiency. J Nutr 130: 1344S-1349S.
    • (2000) J Nutr , vol.130
    • Hambidge, M.1
  • 7
    • 33845969541 scopus 로고    scopus 로고
    • Identification of a mutation in SLC30A2 (ZnT-2) in women with low milk zinc concentration that results in transient neonatal zinc deficiency
    • Chowanadisai W, Lonnerdal B, Kelleher SL, (2006) Identification of a mutation in SLC30A2 (ZnT-2) in women with low milk zinc concentration that results in transient neonatal zinc deficiency. J Biol Chem 281: 39699-39707.
    • (2006) J Biol Chem , vol.281 , pp. 39699-39707
    • Chowanadisai, W.1    Lonnerdal, B.2    Kelleher, S.L.3
  • 8
    • 0036648254 scopus 로고    scopus 로고
    • Identification of SLC39A4, a gene involved in acrodermatitis enteropathica
    • Kury S, Dreno B, Bezieau S, Giraudet S, Kharfi M, et al. (2002) Identification of SLC39A4, a gene involved in acrodermatitis enteropathica. Nat Genet 31: 239-240.
    • (2002) Nat Genet , vol.31 , pp. 239-240
    • Kury, S.1    Dreno, B.2    Bezieau, S.3    Giraudet, S.4    Kharfi, M.5
  • 9
    • 0142009677 scopus 로고    scopus 로고
    • Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters
    • Taylor KM, Morgan HE, Johnson A, Hadley LJ, Nicholson RI, (2003) Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters. Biochem J 375: 51-59.
    • (2003) Biochem J , vol.375 , pp. 51-59
    • Taylor, K.M.1    Morgan, H.E.2    Johnson, A.3    Hadley, L.J.4    Nicholson, R.I.5
  • 11
    • 33847176604 scopus 로고    scopus 로고
    • A genome-wide association study identifies novel risk loci for type 2 diabetes
    • Sladek R, Rocheleau G, Rung J, Dina C, Shen L, et al. (2007) A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445: 881-885.
    • (2007) Nature , vol.445 , pp. 881-885
    • Sladek, R.1    Rocheleau, G.2    Rung, J.3    Dina, C.4    Shen, L.5
  • 12
    • 44649187851 scopus 로고    scopus 로고
    • Spondylocheiro dysplastic form of the Ehlers-Danlos syndrome-an autosomal-recessive entity caused by mutations in the zinc transporter gene SLC39A13
    • Giunta C, Elcioglu NH, Albrecht B, Eich G, Chambaz C, et al. (2008) Spondylocheiro dysplastic form of the Ehlers-Danlos syndrome-an autosomal-recessive entity caused by mutations in the zinc transporter gene SLC39A13. Am J Hum Genet 82: 1290-1305.
    • (2008) Am J Hum Genet , vol.82 , pp. 1290-1305
    • Giunta, C.1    Elcioglu, N.H.2    Albrecht, B.3    Eich, G.4    Chambaz, C.5
  • 13
    • 0036308552 scopus 로고    scopus 로고
    • A novel member of a zinc transporter family is defective in acrodermatitis enteropathica
    • Wang K, Zhou B, Kuo YM, Zemansky J, Gitschier J, (2002) A novel member of a zinc transporter family is defective in acrodermatitis enteropathica. Am J Hum Genet 71: 66-73.
    • (2002) Am J Hum Genet , vol.71 , pp. 66-73
    • Wang, K.1    Zhou, B.2    Kuo, Y.M.3    Zemansky, J.4    Gitschier, J.5
  • 16
    • 0035713724 scopus 로고    scopus 로고
    • The "metal transcription factor" MTF-1: biological facts and medical implications
    • Lichtlen P, Schaffner W, (2001) The "metal transcription factor" MTF-1: biological facts and medical implications. Swiss Med Wkly 131: 647-652.
    • (2001) Swiss Med Wkly , vol.131 , pp. 647-652
    • Lichtlen, P.1    Schaffner, W.2
  • 18
    • 0034011588 scopus 로고    scopus 로고
    • Overview of zinc absorption and excretion in the human gastrointestinal tract
    • Krebs NF, (2000) Overview of zinc absorption and excretion in the human gastrointestinal tract. J Nutr 130: 1374S-1377S.
    • (2000) J Nutr , vol.130
    • Krebs, N.F.1
  • 19
    • 77951118744 scopus 로고    scopus 로고
    • Dietary zinc absorption: A play of Zips and ZnTs in the gut
    • Wang X, Zhou B, (2010) Dietary zinc absorption: A play of Zips and ZnTs in the gut. IUBMB Life 62: 176-182.
    • (2010) IUBMB Life , vol.62 , pp. 176-182
    • Wang, X.1    Zhou, B.2
  • 20
    • 0041355296 scopus 로고    scopus 로고
    • The acrodermatitis enteropathica gene ZIP4 encodes a tissue-specific, zinc-regulated zinc transporter in mice
    • Dufner-Beattie J, Wang F, Kuo YM, Gitschier J, Eide D, et al. (2003) The acrodermatitis enteropathica gene ZIP4 encodes a tissue-specific, zinc-regulated zinc transporter in mice. J Biol Chem 278: 33474-33481.
    • (2003) J Biol Chem , vol.278 , pp. 33474-33481
    • Dufner-Beattie, J.1    Wang, F.2    Kuo, Y.M.3    Gitschier, J.4    Eide, D.5
  • 21
    • 0032574826 scopus 로고    scopus 로고
    • Regulation of the zinc transporter ZnT-1 by dietary zinc
    • McMahon RJ, Cousins RJ, (1998) Regulation of the zinc transporter ZnT-1 by dietary zinc. Proc Natl Acad Sci U S A 95: 4841-4846.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 4841-4846
    • McMahon, R.J.1    Cousins, R.J.2
  • 22
    • 0037315905 scopus 로고    scopus 로고
    • Zinc transporters 1, 2 and 4 are differentially expressed and localized in rats during pregnancy and lactation
    • Liuzzi JP, Bobo JA, Cui L, McMahon RJ, Cousins RJ, (2003) Zinc transporters 1, 2 and 4 are differentially expressed and localized in rats during pregnancy and lactation. J Nutr 133: 342-351.
    • (2003) J Nutr , vol.133 , pp. 342-351
    • Liuzzi, J.P.1    Bobo, J.A.2    Cui, L.3    McMahon, R.J.4    Cousins, R.J.5
  • 23
    • 8444252173 scopus 로고    scopus 로고
    • Mouse zinc transporter 1 gene provides an essential function during early embryonic development
    • Andrews GK, Wang H, Dey SK, Palmiter RD, (2004) Mouse zinc transporter 1 gene provides an essential function during early embryonic development. Genesis 40: 74-81.
    • (2004) Genesis , vol.40 , pp. 74-81
    • Andrews, G.K.1    Wang, H.2    Dey, S.K.3    Palmiter, R.D.4
  • 24
    • 0037151036 scopus 로고    scopus 로고
    • A novel zinc-regulated human zinc transporter, hZTL1, is localized to the enterocyte apical membrane
    • Cragg RA, Christie GR, Phillips SR, Russi RM, Kury S, et al. (2002) A novel zinc-regulated human zinc transporter, hZTL1, is localized to the enterocyte apical membrane. J Biol Chem 277: 22789-22797.
    • (2002) J Biol Chem , vol.277 , pp. 22789-22797
    • Cragg, R.A.1    Christie, G.R.2    Phillips, S.R.3    Russi, R.M.4    Kury, S.5
  • 25
    • 34347237874 scopus 로고    scopus 로고
    • ZnT5 Variant B Is a Bidirectional Zinc Transporter and Mediates Zinc Uptake in Human Intestinal Caco-2 Cells
    • Valentine RA, Jackson KA, Christie GR, Mathers JC, Taylor PM, et al. (2007) ZnT5 Variant B Is a Bidirectional Zinc Transporter and Mediates Zinc Uptake in Human Intestinal Caco-2 Cells. J Biol Chem 282: 14389-14393.
    • (2007) J Biol Chem , vol.282 , pp. 14389-14393
    • Valentine, R.A.1    Jackson, K.A.2    Christie, G.R.3    Mathers, J.C.4    Taylor, P.M.5
  • 26
    • 0036102081 scopus 로고    scopus 로고
    • Zinc ions and cation diffusion facilitator proteins regulate Ras-mediated signaling
    • Bruinsma JJ, Jirakulaporn T, Muslin AJ, Kornfeld K, (2002) Zinc ions and cation diffusion facilitator proteins regulate Ras-mediated signaling. Dev Cell 2: 567-578.
    • (2002) Dev Cell , vol.2 , pp. 567-578
    • Bruinsma, J.J.1    Jirakulaporn, T.2    Muslin, A.J.3    Kornfeld, K.4
  • 27
    • 49849084620 scopus 로고    scopus 로고
    • Identification of mutations in Caenorhabditis elegans that cause resistance to high levels of dietary zinc and analysis using a genomewide map of single nucleotide polymorphisms scored by pyrosequencing
    • Bruinsma JJ, Schneider DL, Davis DE, Kornfeld K, (2008) Identification of mutations in Caenorhabditis elegans that cause resistance to high levels of dietary zinc and analysis using a genomewide map of single nucleotide polymorphisms scored by pyrosequencing. Genetics 179: 811-828.
    • (2008) Genetics , vol.179 , pp. 811-828
    • Bruinsma, J.J.1    Schneider, D.L.2    Davis, D.E.3    Kornfeld, K.4
  • 28
    • 70350168810 scopus 로고    scopus 로고
    • The cation diffusion facilitator gene cdf-2 mediates zinc metabolism in Caenorhabditis elegans
    • Davis DE, Roh HC, Deshmukh K, Bruinsma JJ, Schneider DL, et al. (2009) The cation diffusion facilitator gene cdf-2 mediates zinc metabolism in Caenorhabditis elegans. Genetics 182: 1015-1033.
    • (2009) Genetics , vol.182 , pp. 1015-1033
    • Davis, D.E.1    Roh, H.C.2    Deshmukh, K.3    Bruinsma, J.J.4    Schneider, D.L.5
  • 29
    • 79953766071 scopus 로고    scopus 로고
    • Histidine Protects Against Zinc and Nickel Toxicity in Caenorhabditis elegans
    • doi:10.1371/journal.pgen.1002013
    • Murphy JT, Bruinsma JJ, Schneider DL, Collier S, Guthrie J, et al. (2011) Histidine Protects Against Zinc and Nickel Toxicity in Caenorhabditis elegans. PLoS Genet 7: e1002013 doi:10.1371/journal.pgen.1002013.
    • (2011) PLoS Genet , vol.7
    • Murphy, J.T.1    Bruinsma, J.J.2    Schneider, D.L.3    Collier, S.4    Guthrie, J.5
  • 30
    • 84855471897 scopus 로고    scopus 로고
    • Lysosome-related organelles in intestinal cells are a zinc storage site in C. elegans
    • Roh HC, Collier S, Guthrie J, Robertson JD, Kornfeld K, (2012) Lysosome-related organelles in intestinal cells are a zinc storage site in C. elegans. Cell Metab 15: 88-99.
    • (2012) Cell Metab , vol.15 , pp. 88-99
    • Roh, H.C.1    Collier, S.2    Guthrie, J.3    Robertson, J.D.4    Kornfeld, K.5
  • 31
    • 0842328578 scopus 로고    scopus 로고
    • Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase
    • Yoder JH, Chong H, Guan KL, Han M, (2004) Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase. Embo J 23: 111-119.
    • (2004) Embo J , vol.23 , pp. 111-119
    • Yoder, J.H.1    Chong, H.2    Guan, K.L.3    Han, M.4
  • 32
    • 0027449990 scopus 로고
    • The novel metallothionein genes of Caenorhabditis elegans. Structural organization and inducible, cell-specific expression
    • Freedman JH, Slice LW, Dixon D, Fire A, Rubin CS, (1993) The novel metallothionein genes of Caenorhabditis elegans. Structural organization and inducible, cell-specific expression. J Biol Chem 268: 2554-2564.
    • (1993) J Biol Chem , vol.268 , pp. 2554-2564
    • Freedman, J.H.1    Slice, L.W.2    Dixon, D.3    Fire, A.4    Rubin, C.S.5
  • 33
    • 3342901591 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins
    • Huffman DL, Abrami L, Sasik R, Corbeil J, van der Goot FG, et al. (2004) Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins. Proc Natl Acad Sci U S A 101: 10995-11000.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 10995-11000
    • Huffman, D.L.1    Abrami, L.2    Sasik, R.3    Corbeil, J.4    van der Goot, F.G.5
  • 34
    • 34748922791 scopus 로고    scopus 로고
    • Toxicogenomic analysis of Caenorhabditis elegans reveals novel genes and pathways involved in the resistance to cadmium toxicity
    • Cui Y, McBride SJ, Boyd WA, Alper S, Freedman JH, (2007) Toxicogenomic analysis of Caenorhabditis elegans reveals novel genes and pathways involved in the resistance to cadmium toxicity. Genome Biol 8: R122.
    • (2007) Genome Biol , vol.8
    • Cui, Y.1    McBride, S.J.2    Boyd, W.A.3    Alper, S.4    Freedman, J.H.5
  • 35
    • 0030801002 scopus 로고    scopus 로고
    • Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
    • Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, et al. (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25: 3389-3402.
    • (1997) Nucleic Acids Res , vol.25 , pp. 3389-3402
    • Altschul, S.F.1    Madden, T.L.2    Schaffer, A.A.3    Zhang, J.4    Zhang, Z.5
  • 36
    • 38549105096 scopus 로고    scopus 로고
    • Trans-splicing and operons
    • Blumenthal T, (2005) Trans-splicing and operons. WormBook pp. 1-9.
    • (2005) WormBook , pp. 1-9
    • Blumenthal, T.1
  • 37
    • 43749090437 scopus 로고    scopus 로고
    • Deletion of a histidine-rich loop of AtMTP1, a vacuolar Zn(2+)/H(+) antiporter of Arabidopsis thaliana, stimulates the transport activity
    • Kawachi M, Kobae Y, Mimura T, Maeshima M, (2008) Deletion of a histidine-rich loop of AtMTP1, a vacuolar Zn(2+)/H(+) antiporter of Arabidopsis thaliana, stimulates the transport activity. J Biol Chem 283: 8374-8383.
    • (2008) J Biol Chem , vol.283 , pp. 8374-8383
    • Kawachi, M.1    Kobae, Y.2    Mimura, T.3    Maeshima, M.4
  • 38
    • 0034012029 scopus 로고    scopus 로고
    • Metallothionein expression in animals: a physiological perspective on function
    • Davis SR, Cousins RJ, (2000) Metallothionein expression in animals: a physiological perspective on function. J Nutr 130: 1085-1088.
    • (2000) J Nutr , vol.130 , pp. 1085-1088
    • Davis, S.R.1    Cousins, R.J.2
  • 40
    • 33947158693 scopus 로고    scopus 로고
    • Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle
    • Schroeder LK, Kremer S, Kramer MJ, Currie E, Kwan E, et al. (2007) Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle. Mol Biol Cell 18: 995-1008.
    • (2007) Mol Biol Cell , vol.18 , pp. 995-1008
    • Schroeder, L.K.1    Kremer, S.2    Kramer, M.J.3    Currie, E.4    Kwan, E.5
  • 41
    • 33746929895 scopus 로고    scopus 로고
    • Zinc transporters and the cellular trafficking of zinc
    • Eide DJ, (2006) Zinc transporters and the cellular trafficking of zinc. Biochim Biophys Acta 1763: 711-722.
    • (2006) Biochim Biophys Acta , vol.1763 , pp. 711-722
    • Eide, D.J.1
  • 42
    • 68749108391 scopus 로고    scopus 로고
    • Zinc transporter-2 (ZnT2) variants are localized to distinct subcellular compartments and functionally transport zinc
    • Lopez V, Kelleher SL, (2009) Zinc transporter-2 (ZnT2) variants are localized to distinct subcellular compartments and functionally transport zinc. Biochem J 422: 43-52.
    • (2009) Biochem J , vol.422 , pp. 43-52
    • Lopez, V.1    Kelleher, S.L.2
  • 43
    • 34249850816 scopus 로고    scopus 로고
    • Splice variants of the human zinc transporter ZnT5 (SLC30A5) are differentially localized and regulated by zinc through transcription and mRNA stability
    • Jackson KA, Helston RM, McKay JA, O'Neill ED, Mathers JC, et al. (2007) Splice variants of the human zinc transporter ZnT5 (SLC30A5) are differentially localized and regulated by zinc through transcription and mRNA stability. J Biol Chem 282: 10423-10431.
    • (2007) J Biol Chem , vol.282 , pp. 10423-10431
    • Jackson, K.A.1    Helston, R.M.2    McKay, J.A.3    O'Neill, E.D.4    Mathers, J.C.5
  • 44
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner S, (1974) The genetics of Caenorhabditis elegans. Genetics 77: 71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 45
    • 34547781750 scopus 로고    scopus 로고
    • MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0
    • Tamura K, Dudley J, Nei M, Kumar S, (2007) MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 24: 1596-1599.
    • (2007) Mol Biol Evol , vol.24 , pp. 1596-1599
    • Tamura, K.1    Dudley, J.2    Nei, M.3    Kumar, S.4
  • 46
    • 0035099902 scopus 로고    scopus 로고
    • Creation of low-copy integrated transgenic lines in Caenorhabditis elegans
    • Praitis V, Casey E, Collar D, Austin J, (2001) Creation of low-copy integrated transgenic lines in Caenorhabditis elegans. Genetics 157: 1217-1226.
    • (2001) Genetics , vol.157 , pp. 1217-1226
    • Praitis, V.1    Casey, E.2    Collar, D.3    Austin, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.