Synergism of ursolic acid derivative US597 with 2-deoxy-D-glucose to preferentially induce tumor cell death by dual-targeting of apoptosis and glycolysis

Scientific Reports

Volumn 4, Issue , 2015, Pages

  Wang, Jichuang ^a   Jiang, Zhou ^a   Xiang, Liping ^a   Li, Yuanfang ^a   Ou, Minrui ^a   Yang, Xiang ^a   Shao, Jingwei ^a   Lu, Yusheng ^a   Lin, Lifeng ^a   Chen, Jianzhong ^b   Dai, Yun ^c   Jia, Lee ^a  

^a FUZHOU UNIVERSITY   (China)

^b FUJIAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3-ACETOXYURS-12-EN-28-OIC ACID HEXAMETHYLENEDIAMINE; ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENT; DEOXYGLUCOSE; GLUCOKINASE; HEXOKINASE; LACTIC ACID; TRITERPENE; URSOLIC ACID;

ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; BIOSYNTHESIS; CANCER TRANSPLANTATION; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; DRUG POTENTIATION; FEMALE; G1 PHASE CELL CYCLE CHECKPOINT; GLYCOLYSIS; HELA CELL LINE; HEPG2 CELL LINE; HUMAN; LIVER NEOPLASMS; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; TUMOR CELL LINE;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; DEOXYGLUCOSE; DRUG SYNERGISM; FEMALE; G1 PHASE CELL CYCLE CHECKPOINTS; GLUCOKINASE; GLYCOLYSIS; HELA CELLS; HEP G2 CELLS; HEXOKINASE; HUMANS; LACTIC ACID; LIVER NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; NEOPLASM TRANSPLANTATION; TRITERPENES;

EID: 84908154677     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep05006     Document Type: Article

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