The synthesis of ursolic acid derivatives with cytotoxic activity and the investigation of their preliminary mechanism of action

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 2, 2009, Pages 848-854

  Meng, Yan Qiu ^a   Liu, Dan ^a   Cai, Ling Li ^a   Chen, Hong ^b   Cao, Bo ^b   Wang, Yi Zheng ^b  

^a SHENYANG UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

^b MEDICAL COLLEGE OF CHINESE PEOPLE'S ARMED POLICE FORCES   (China)

Author keywords

Anti tumor activity; Triterpene; Ursolic acid derivatives

Indexed keywords

DNA FRAGMENT; N (3BETA ACETOXY URS 12 EN 28 OYL) 2 AMINO 1 PROPANOL ACETATE; N (3BETA ACETOXY URS 12 EN 28 OYL) 2 AMINOETHANOL ACETATE; UNCLASSIFIED DRUG; URSOLIC ACID DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; DRUG SYNTHESIS; FLOW CYTOMETRY; HELA CELL; HUMAN; HUMAN CELL;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; DNA FRAGMENTATION; HUMANS; TRITERPENES;

EID: 58549091468     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.11.036     Document Type: Article

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