In vitro and in vivo anticancer activity evaluation of ursolic acid derivatives

European Journal of Medicinal Chemistry

Volumn 46, Issue 7, 2011, Pages 2652-2661

  Shao, Jing Wei ^a   Dai, Yong Chao ^a   Xue, Jin Ping ^a   Wang, Ji Chuang ^a   Lin, Feng Ping ^a   Guo, Yang Hao ^a  

^a FUZHOU UNIVERSITY   (China)

Author keywords

Anticancer activity; Apoptosis; Cytotoxicity; Synthesis; Ursolic acid derivatives

Indexed keywords

3BETA ACETOXY URS 12 EN 28 OIC ACID ETHYL ESTER; 3BETA ACETOXY URS 12 EN 28 OIC ACID N BUTYL ESTER; 3BETA ACETOXY URS 12 EN 28 OIC ACID PROPYL ESTER; CASPASE 3; CYCLOPHOSPHAMIDE; N (3BETA ACETOXY URS 12 EN 28 OYL) 2 AMINODIETHANOL; N (3BETA ACETOXY URS 12 EN 28 OYL) AMINO N (2 HYDROXYETHYL)PIPERAZINE; N (3BETA ACETOXY URS 12 EN 28 OYL)AMINO 1 HYDROXYETHYLETHOXY PIPERAZINE; N (3BETA ACETOXY URS 12 EN 28 OYL)AMINO 1 HYDROXYETHYLETHOXYPIPERAZINE; N (3BETA ACETOXY URS 12 EN 28 OYL)AMINO 4 PIPERIDINETHANOL; N (3BETA HYDROXY 12 EN 28 OYL] AMINO N (2 HYDROXYETHYL)PIPERAZINE; UNCLASSIFIED DRUG; URSOLIC ACID; URSOLIC ACID DERIVATIVE; ANTINEOPLASTIC AGENT; TRITERPENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE S PHASE; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; LIVER CARCINOMA; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; ANIMAL; CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; DRUG SCREENING; FIBROBLAST; GENE EXPRESSION; GENETICS; HELA CELL LINE; HEPG2 CELL LINE; LIVER NEOPLASMS; METABOLISM; PATHOLOGY; SYNTHESIS; TUMOR CELL LINE; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CRYSTALLOGRAPHY, X-RAY; FIBROBLASTS; GENE EXPRESSION; HELA CELLS; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MICE; TRITERPENES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79957503743     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.03.050     Document Type: Article

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