-
1
-
-
84862868998
-
Current epidemiology and growing resistance of gram-negative pathogens
-
Livermore DM. Current epidemiology and growing resistance of gram-negative pathogens. Korean J Intern Med. 2012;27(2):128-142.
-
(2012)
Korean J Intern Med
, vol.27
, Issue.2
, pp. 128-142
-
-
Livermore, D.M.1
-
2
-
-
57049185166
-
De novo designed synthetic mimics of antimicrobial peptides
-
Scott RW, DeGrado WF, Tew GN. De novo designed synthetic mimics of antimicrobial peptides. Curr Opin Biotechnol. 2008;19(6):620-627.
-
(2008)
Curr Opin Biotechnol
, vol.19
, Issue.6
, pp. 620-627
-
-
Scott, R.W.1
Degrado, W.F.2
Tew, G.N.3
-
3
-
-
75449102744
-
De novo design of antimicrobial polymers, foldamers, and small molecules: From discovery to practical applications
-
Tew GN, Scott RW, Klein ML, Degrado WF. De novo design of antimicrobial polymers, foldamers, and small molecules: from discovery to practical applications. Acc Chem Res. 2010;43(1):30-39.
-
(2010)
Acc Chem Res
, vol.43
, Issue.1
, pp. 30-39
-
-
Tew, G.N.1
Scott, R.W.2
Klein, M.L.3
Degrado, W.F.4
-
4
-
-
0033151774
-
Mechanism of interaction of different classes of cationic antimicrobial peptides with planar bilayers and with the cytoplasmic membrane of Escherichia coli
-
Wu M, Maier E, Benz R, Hancock RE. Mechanism of interaction of different classes of cationic antimicrobial peptides with planar bilayers and with the cytoplasmic membrane of Escherichia coli. Biochemistry. 1999;38(22):7235-7242.
-
(1999)
Biochemistry
, vol.38
, Issue.22
, pp. 7235-7242
-
-
Wu, M.1
Maier, E.2
Benz, R.3
Hancock, R.E.4
-
5
-
-
0033915369
-
Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria
-
Friedrich CL, Moyles D, Beveridge TJ, Hancock RE. Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria. Antimicrob Agents Chemother. 2000;44(8):2086-2092.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, Issue.8
, pp. 2086-2092
-
-
Friedrich, C.L.1
Moyles, D.2
Beveridge, T.J.3
Hancock, R.E.4
-
6
-
-
0034424412
-
Interactions of bacterial cationic peptide antibiotics with outer and cytoplasmic membranes of Pseudomonas aeruginosa
-
Zhang L, Dhillon P, Yan H, Farmer S, Hancock RE. Interactions of bacterial cationic peptide antibiotics with outer and cytoplasmic membranes of Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2000;44(12):3317-3321.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, Issue.12
, pp. 3317-3321
-
-
Zhang, L.1
Dhillon, P.2
Yan, H.3
Farmer, S.4
Hancock, R.E.5
-
7
-
-
33845699790
-
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies
-
Hancock RE, Sahl HG. Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nat Biotechnol. 2006;24(12):1551-1557.
-
(2006)
Nat Biotechnol
, vol.24
, Issue.12
, pp. 1551-1557
-
-
Hancock, R.E.1
Sahl, H.G.2
-
8
-
-
52049122588
-
Role of antimicrobial peptides in host defense against mycobacterial infections
-
Méndez-Samperio P. Role of antimicrobial peptides in host defense against mycobacterial infections. Peptides. 2008;29(10):1836-1841.
-
(2008)
Peptides
, vol.29
, Issue.10
, pp. 1836-1841
-
-
Méndez-Samperio, P.1
-
9
-
-
0032007854
-
Cationic peptides: A new source of antibiotics
-
Hancock RE, Lehrer R. Cationic peptides: a new source of antibiotics. Trends Biotechnol. 1998;16(2):82-88.
-
(1998)
Trends Biotechnol
, vol.16
, Issue.2
, pp. 82-88
-
-
Hancock, R.E.1
Lehrer, R.2
-
10
-
-
33748413776
-
Antibacterial peptides for therapeutic use: Obstacles and realistic outlook
-
Marr AK, Gooderham WJ, Hancock RE. Antibacterial peptides for therapeutic use: obstacles and realistic outlook. Curr Opin Pharmacol. 2006;6(5):468-472.
-
(2006)
Curr Opin Pharmacol
, vol.6
, Issue.5
, pp. 468-472
-
-
Marr, A.K.1
Gooderham, W.J.2
Hancock, R.E.3
-
11
-
-
14544282377
-
Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria?
-
Brogden KA. Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat Rev Microbiol. 2005;3(3):238-250.
-
(2005)
Nat Rev Microbiol
, vol.3
, Issue.3
, pp. 238-250
-
-
Brogden, K.A.1
-
12
-
-
0032717886
-
Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides
-
Shai Y. Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides. Biochim Biophys Acta. 1999;1462(1-2):55-70.
-
(1999)
Biochim Biophys Acta
, vol.1462
, Issue.1-2
, pp. 55-70
-
-
Shai, Y.1
-
13
-
-
0036948138
-
Mode of action of membrane active antimicrobial peptides
-
Shai Y. Mode of action of membrane active antimicrobial peptides. Biopolymers. 2002;66(4):236-248.
-
(2002)
Biopolymers
, vol.66
, Issue.4
, pp. 236-248
-
-
Shai, Y.1
-
14
-
-
79953148897
-
Alpha-helical cationic antimicrobial peptides: Relationships of structure and function
-
Huang Y, Huang J, Chen Y. Alpha-helical cationic antimicrobial peptides: relationships of structure and function. Protein Cell. 2010;1(2):143-152.
-
(2010)
Protein Cell
, vol.1
, Issue.2
, pp. 143-152
-
-
Huang, Y.1
Huang, J.2
Chen, Y.3
-
15
-
-
83655193502
-
Lu W. α-Defensins in human innate immunity
-
Lehrer R., Lu W. α-Defensins in human innate immunity. Immunol Rev. 2012;245(1):84-112.
-
(2012)
Immunol Rev
, vol.245
, Issue.1
, pp. 84-112
-
-
Lehrer, R.1
-
16
-
-
78449236736
-
Antimicrobial peptides: Primeval molecules or future drugs?
-
Peters BM, Shirtliff ME, Jabra-Rizk MA. Antimicrobial peptides: primeval molecules or future drugs? PLoS Pathog. 2010;6(10): e1001067.
-
(2010)
PLoS Pathog
, vol.6
, Issue.10
-
-
Peters, B.M.1
Shirtliff, M.E.2
Jabra-Rizk, M.A.3
-
17
-
-
33749528779
-
Antifungal activity from 14-helical beta-peptides
-
Karlsson AJ, Pomerantz WC, Weisblum B, Gellman SH, Palecek SP. Antifungal activity from 14-helical beta-peptides. J Am Chem Soc. 2006;128(39):12630-12631.
-
(2006)
J Am Chem Soc
, vol.128
, Issue.39
, pp. 12630-12631
-
-
Karlsson, A.J.1
Pomerantz, W.C.2
Weisblum, B.3
Gellman, S.H.4
Palecek, S.P.5
-
18
-
-
67650806449
-
Effect of sequence and structural properties on 14-helical beta-peptide activity against Candida albicans planktonic cells and biofilms
-
Karlsson AJ, Pomerantz WC, Neilsen KJ, Gellman SH, Palecek SP. Effect of sequence and structural properties on 14-helical beta-peptide activity against Candida albicans planktonic cells and biofilms. ACS Chem Biol. 2009;4(7):567-579.
-
(2009)
ACS Chem Biol
, vol.4
, Issue.7
, pp. 567-579
-
-
Karlsson, A.J.1
Pomerantz, W.C.2
Neilsen, K.J.3
Gellman, S.H.4
Palecek, S.P.5
-
19
-
-
77956511575
-
Polyelectrolyte multilayers fabricated from antifungal β-peptides: Design of surfaces that exhibit antifungal activity against Candida albicans
-
Karlsson AJ, Flessner RM, Gellman SH, Lynn DM, Palecek SP. Polyelectrolyte multilayers fabricated from antifungal β-peptides: design of surfaces that exhibit antifungal activity against Candida albicans. Biomacromolecules. 2010;11(9):2321-2328.
-
(2010)
Biomacromolecules
, vol.11
, Issue.9
, pp. 2321-2328
-
-
Karlsson, A.J.1
Flessner, R.M.2
Gellman, S.H.3
Lynn, D.M.4
Palecek, S.P.5
-
20
-
-
38149143037
-
Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides
-
Chongsiriwatana NP, Patch JA, Czyzewski AM, et al. Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides. Proc Natl Acad Sci U S A. 2008;105(8):2794-2799.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.8
, pp. 2794-2799
-
-
Chongsiriwatana, N.P.1
Patch, J.A.2
Czyzewski, A.M.3
-
21
-
-
77954373564
-
Antimicrobial, hemolytic, and cytotoxic activities of beta-peptoid-peptide hybrid oligomers: Improved properties compared to natural AMPs
-
Olsen CA, Ziegler HL, Nielsen HM, Frimodt-Møller N, Jaroszewski JW, Franzyk H. Antimicrobial, hemolytic, and cytotoxic activities of beta-peptoid-peptide hybrid oligomers: improved properties compared to natural AMPs. Chembiochem. 2010;11(10):1356-1360.
-
(2010)
Chembiochem
, vol.11
, Issue.10
, pp. 1356-1360
-
-
Olsen, C.A.1
Ziegler, H.L.2
Nielsen, H.M.3
Frimodt-Møller, N.4
Jaroszewski, J.W.5
Franzyk, H.6
-
22
-
-
79956305511
-
Antimicrobial peptoids are effective against Pseudomonas aeruginosa biofilms
-
Kapoor R, Wadman MW, Dohm MT, Czyzewski AM, Spormann AM, Barron AE. Antimicrobial peptoids are effective against Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother. 2011;55(6): 3054-3057.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, Issue.6
, pp. 3054-3057
-
-
Kapoor, R.1
Wadman, M.W.2
Dohm, M.T.3
Czyzewski, A.M.4
Spormann, A.M.5
Barron, A.E.6
-
24
-
-
79956322803
-
Efficacy of antimicrobial peptoids against Mycobacterium tuberculosis
-
Kapoor R, Eimerman PR, Hardy JW, Cirillo JD, Contag CH, Barron AE. Efficacy of antimicrobial peptoids against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2011;55(6):3058-3062.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, Issue.6
, pp. 3058-3062
-
-
Kapoor, R.1
Eimerman, P.R.2
Hardy, J.W.3
Cirillo, J.D.4
Contag, C.H.5
Barron, A.E.6
-
25
-
-
84555188465
-
A comparison of linear and cyclic peptoid oligomers as potent antimicrobial agents
-
Huang ML, Shin SB, Benson MA, Torres VJ, Kirshenbaum K. A comparison of linear and cyclic peptoid oligomers as potent antimicrobial agents. ChemMedChem. 2012;7(1):114-122.
-
(2012)
ChemMedChem
, vol.7
, Issue.1
, pp. 114-122
-
-
Huang, M.L.1
Shin, S.B.2
Benson, M.A.3
Torres, V.J.4
Kirshenbaum, K.5
-
26
-
-
78049442515
-
Activity of antimicrobial peptide mimetics in the oral cavity
-
Hua J, Yamarthy R, Felsenstein S, Scott RW, Markowitz K, Diamond G. Activity of antimicrobial peptide mimetics in the oral cavity: I. Activity against biofilms of Candida albicans. Mol Oral Microbiol. 2010;25(6):418-425.
-
(2010)
Mol Oral Microbiol
, vol.25
, Issue.6
, pp. 418-425
-
-
Hua, J.1
Yamarthy, R.2
Felsenstein, S.3
Scott, R.W.4
Markowitz, K.5
Diamond, G.6
-
27
-
-
78049434581
-
Activity of antimicrobial peptide mimetics in the oral cavity: II. Activity against periopathogenic biofilms and anti-inflammatory activity
-
Hua J, Scott RW, Diamond G. Activity of antimicrobial peptide mimetics in the oral cavity: II. Activity against periopathogenic biofilms and anti-inflammatory activity. Mol Oral Microbiol. 2010;25(6):426-432.
-
(2010)
Mol Oral Microbiol
, vol.25
, Issue.6
, pp. 426-432
-
-
Hua, J.1
Scott, R.W.2
Diamond, G.3
-
28
-
-
61949116417
-
Recent progress in the discovery of macrocyclic compounds as potential anti-infective therapeutics
-
Obrecht D, Robinson JA, Bernardini F, et al. Recent progress in the discovery of macrocyclic compounds as potential anti-infective therapeutics. Curr Med Chem. 2009;16(1):42-65.
-
(2009)
Curr Med Chem
, vol.16
, Issue.1
, pp. 42-65
-
-
Obrecht, D.1
Robinson, J.A.2
Bernardini, F.3
-
29
-
-
77149159117
-
Peptidomimetic antibiotics target outer-membrane biogenesis in Pseudomonas aeruginosa
-
Srinivas N, Jetter P, Ueberbacher BJ, et al. Peptidomimetic antibiotics target outer-membrane biogenesis in Pseudomonas aeruginosa. Science. 2010;327(5968):1010-1013.
-
(2010)
Science
, vol.327
, Issue.5968
, pp. 1010-1013
-
-
Srinivas, N.1
Jetter, P.2
Ueberbacher, B.J.3
-
30
-
-
79951723504
-
Design and synthesis of AApeptides: A new class of peptide mimics
-
Hu Y, Li X, Sebti SM, Chen J, Cai J. Design and synthesis of AApeptides: a new class of peptide mimics. Bioorg Med Chem Lett. 2011;21(5):1469-1471.
-
(2011)
Bioorg Med Chem Lett
, vol.21
, Issue.5
, pp. 1469-1471
-
-
Hu, Y.1
Li, X.2
Sebti, S.M.3
Chen, J.4
Cai, J.5
-
31
-
-
84881056113
-
AApeptides as a new class of antimicrobial agents
-
Niu Y, Wu H, Li Y, et al. AApeptides as a new class of antimicrobial agents. Org Biomol Chem. 2013;11(26):4283-4290.
-
(2013)
Org Biomol Chem
, vol.11
, Issue.26
, pp. 4283-4290
-
-
Niu, Y.1
Wu, H.2
Li, Y.3
-
33
-
-
33749511848
-
Amphiphilic poly(phenyleneethynylene)s can mimic antimicrobial peptide membrane disordering effect by membrane insertion
-
Ishitsuka Y, Arnt L, Majewski J, et al. Amphiphilic poly(phenyleneethynylene)s can mimic antimicrobial peptide membrane disordering effect by membrane insertion. J Am Chem Soc. 2006;128(40):13123-13129.
-
(2006)
J Am Chem Soc
, vol.128
, Issue.40
, pp. 13123-13129
-
-
Ishitsuka, Y.1
Arnt, L.2
Majewski, J.3
-
34
-
-
73349095395
-
Consequences of isostructural main-chain modifications for the design of antimicrobial foldamers: Helical mimics of host-defense peptides based on a heterogeneous amide/urea backbone
-
Claudon P, Violette A, Lamour K, et al. Consequences of isostructural main-chain modifications for the design of antimicrobial foldamers: helical mimics of host-defense peptides based on a heterogeneous amide/urea backbone. Angew Chem Int Ed Engl. 2010;49(2):333-336.
-
(2010)
Angew Chem Int Ed Engl
, vol.49
, Issue.2
, pp. 333-336
-
-
Claudon, P.1
Violette, A.2
Lamour, K.3
-
35
-
-
33746904737
-
A simple gamma-backbone modification preorganizes peptide nucleic acid into a helical structure
-
Dragulescu-Andrasi A, Rapireddy S, Frezza BM, Gayathri C, Gil RR, Ly DH. A simple gamma-backbone modification preorganizes peptide nucleic acid into a helical structure. J Am Chem Soc. 2006;128(31): 10258-10267.
-
(2006)
J Am Chem Soc
, vol.128
, Issue.31
, pp. 10258-10267
-
-
Dragulescu-Andrasi, A.1
Rapireddy, S.2
Frezza, B.M.3
Gayathri, C.4
Gil, R.R.5
Ly, D.H.6
-
36
-
-
21844475376
-
Lysine-based peptide nucleic acids (PNAs) with strong chiral constraint: Control of helix handedness and DNA binding by chirality
-
Tedeschi T, Sforza S, Dossena A, Corradini R, Marchelli R. Lysine-based peptide nucleic acids (PNAs) with strong chiral constraint: control of helix handedness and DNA binding by chirality. Chirality. 2005;17 Suppl:S196-S204.
-
(2005)
Chirality
, vol.17
, pp. S196-S204
-
-
Tedeschi, T.1
Sforza, S.2
Dossena, A.3
Corradini, R.4
Marchelli, R.5
-
37
-
-
28244463898
-
Detection of the R553X DNA single point mutation related to cystic fibrosis by a “chiral box” D-lysine-peptide nucleic acid probe by capillary electrophoresis
-
Tedeschi T, Chiari M, Galaverna G, et al. Detection of the R553X DNA single point mutation related to cystic fibrosis by a “chiral box” D-lysine-peptide nucleic acid probe by capillary electrophoresis. Electrophoresis. 2005;26(22):4310-4316.
-
(2005)
Electrophoresis
, vol.26
, Issue.22
, pp. 4310-4316
-
-
Tedeschi, T.1
Chiari, M.2
Galaverna, G.3
-
38
-
-
79954444519
-
Design and synthesis of amidine-type peptide bond isosteres: Application of nitrile oxide derivatives as active ester equivalents in peptide and peptidomimetics synthesis
-
Inokuchi E, Yamada A, Hozumi K, et al. Design and synthesis of amidine-type peptide bond isosteres: application of nitrile oxide derivatives as active ester equivalents in peptide and peptidomimetics synthesis. Org Biomol Chem. 2011;9(9):3421-3427.
-
(2011)
Org Biomol Chem
, vol.9
, Issue.9
, pp. 3421-3427
-
-
Inokuchi, E.1
Yamada, A.2
Hozumi, K.3
-
39
-
-
80051709994
-
Non-hemolytic α-AApeptides as antimicrobial peptidomimetics
-
Padhee S, Hu Y, Niu Y, et al. Non-hemolytic α-AApeptides as antimicrobial peptidomimetics. Chem Commun (Camb). 2011;47(34): 9729-9731.
-
(2011)
Chem Commun (Camb)
, vol.47
, Issue.34
, pp. 9729-9731
-
-
Padhee, S.1
Hu, Y.2
Niu, Y.3
-
40
-
-
80155158120
-
Identification of γ-AApeptides with potent and broad-spectrum antimicrobial activity
-
Niu Y, Padhee S, Wu H, et al. Identification of γ-AApeptides with potent and broad-spectrum antimicrobial activity. Chem Commun (Camb). 2011;47(44):12197-12199.
-
(2011)
Chem Commun (Camb)
, vol.47
, Issue.44
, pp. 12197-12199
-
-
Niu, Y.1
Padhee, S.2
Wu, H.3
-
41
-
-
84886634658
-
Cyclic constraints on conformational flexibility in γ-peptides: Conformation specific IR and UV spectroscopy
-
Walsh PS, Kusaka R, Buchanan EG, et al. Cyclic constraints on conformational flexibility in γ-peptides: conformation specific IR and UV spectroscopy. J Phys Chem A. 2013;117(47):12350-12362.
-
(2013)
J Phys Chem A
, vol.117
, Issue.47
, pp. 12350-12362
-
-
Walsh, P.S.1
Kusaka, R.2
Buchanan, E.G.3
-
42
-
-
81855190701
-
Evolution of amide stacking in larger γ-peptides: Triamide H-bonded cycles
-
James WH, Buchanan EG, Müller CW, et al. Evolution of amide stacking in larger γ-peptides: triamide H-bonded cycles. J Phys Chem A. 2011;115(47):13783-13798.
-
(2011)
J Phys Chem A
, vol.115
, Issue.47
, pp. 13783-13798
-
-
James, W.H.1
Buchanan, E.G.2
Müller, C.W.3
-
43
-
-
84863628156
-
Solid-phase synthesis of γ-AApeptides using a submonomeric approach
-
Wu H, Amin MN, Niu Y, et al. Solid-phase synthesis of γ-AApeptides using a submonomeric approach. Org Lett. 2012;14(13):3446-3449.
-
(2012)
Org Lett
, vol.14
, Issue.13
, pp. 3446-3449
-
-
Wu, H.1
Amin, M.N.2
Niu, Y.3
-
44
-
-
80052780538
-
γ-AApeptides bind to RNA by mimicking RNA-binding proteins
-
Niu Y, Jones AJ, Wu H, Varani G, Cai J. γ-AApeptides bind to RNA by mimicking RNA-binding proteins. Org Biomol Chem. 2011;9(19):6604-6609.
-
(2011)
Org Biomol Chem
, vol.9
, Issue.19
, pp. 6604-6609
-
-
Niu, Y.1
Jones, A.J.2
Wu, H.3
Varani, G.4
Cai, J.5
-
45
-
-
84863903214
-
Radiolabeled γ-AApeptides: A new class of tracers for positron emission tomography
-
Yang Y, Niu Y, Hong H, et al. Radiolabeled γ-AApeptides: a new class of tracers for positron emission tomography. Chem Commun (Camb). 2012;48(63):7850-7852.
-
(2012)
Chem Commun (Camb)
, vol.48
, Issue.63
, pp. 7850-7852
-
-
Yang, Y.1
Niu, Y.2
Hong, H.3
-
46
-
-
84860712748
-
Cellular translocation of a γ-AApeptide mimetic of Tat peptide
-
Niu Y, Bai G, Wu H, et al. Cellular translocation of a γ-AApeptide mimetic of Tat peptide. Mol Pharm. 2012;9(5):1529-1534.
-
(2012)
Mol Pharm
, vol.9
, Issue.5
, pp. 1529-1534
-
-
Niu, Y.1
Bai, G.2
Wu, H.3
-
47
-
-
84862932903
-
Cellular uptake of an α-AApeptide
-
Bai G, Padhee S, Niu Y, et al. Cellular uptake of an α-AApeptide. Org Biomol Chem. 2012;10(6):1149-1153.
-
(2012)
Org Biomol Chem
, vol.10
, Issue.6
, pp. 1149-1153
-
-
Bai, G.1
Padhee, S.2
Niu, Y.3
-
48
-
-
33846251959
-
Interplay among folding, sequence, and lipophilicity in the antibacterial and hemolytic activities of alpha/beta-peptides
-
Schmitt MA, Weisblum B, Gellman SH. Interplay among folding, sequence, and lipophilicity in the antibacterial and hemolytic activities of alpha/beta-peptides. J Am Chem Soc. 2007;129(2):417-428.
-
(2007)
J Am Chem Soc
, vol.129
, Issue.2
, pp. 417-428
-
-
Schmitt, M.A.1
Weisblum, B.2
Gellman, S.H.3
-
49
-
-
37849015194
-
Mimicry of antimicrobial host-defense peptides by random copolymers
-
Mowery BP, Lee SE, Kissounko DA, et al. Mimicry of antimicrobial host-defense peptides by random copolymers. J Am Chem Soc. 2007;129(50):15474-15476.
-
(2007)
J Am Chem Soc
, vol.129
, Issue.50
, pp. 15474-15476
-
-
Mowery, B.P.1
Lee, S.E.2
Kissounko, D.A.3
-
50
-
-
84860272888
-
Lipo-γ-AApeptides as a new class of potent and broad-spectrum antimicrobial agents
-
Niu Y, Padhee S, Wu H, et al. Lipo-γ-AApeptides as a new class of potent and broad-spectrum antimicrobial agents. J Med Chem. 2012;55(8):4003-4009.
-
(2012)
J Med Chem
, vol.55
, Issue.8
, pp. 4003-4009
-
-
Niu, Y.1
Padhee, S.2
Wu, H.3
-
51
-
-
78149432931
-
Role of the conformational rigidity in the design of biomimetic antimicrobial compounds
-
Ivankin A, Livne L, Mor A, et al. Role of the conformational rigidity in the design of biomimetic antimicrobial compounds. Angew Chem Int Ed Engl. 2010;49(45):8462-8465.
-
(2010)
Angew Chem Int Ed Engl
, vol.49
, Issue.45
, pp. 8462-8465
-
-
Ivankin, A.1
Livne, L.2
Mor, A.3
-
52
-
-
84871653246
-
Antimicrobial polymers as synthetic mimics of host-defense peptides
-
Kuroda K, Caputo GA. Antimicrobial polymers as synthetic mimics of host-defense peptides. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2013;5(1):49-66.
-
(2013)
Wiley Interdiscip Rev Nanomed Nanobiotechnol
, vol.5
, Issue.1
, pp. 49-66
-
-
Kuroda, K.1
Caputo, G.A.2
-
53
-
-
84885949501
-
Molecular design, structures, and activity of antimicrobial peptide-mimetic polymers
-
Takahashi H, Palermo EF, Yasuhara K, Caputo GA, Kuroda K. Molecular design, structures, and activity of antimicrobial peptide-mimetic polymers. Macromol Biosci. 2013;13(10):1285-1299.
-
(2013)
Macromol Biosci
, vol.13
, Issue.10
, pp. 1285-1299
-
-
Takahashi, H.1
Palermo, E.F.2
Yasuhara, K.3
Caputo, G.A.4
Kuroda, K.5
-
54
-
-
84855275544
-
Relative spatial positions of tryptophan and cationic residues in helical membrane-active peptides determine their cytotoxicity
-
Rekdal Ø, Haug BE, Kalaaji M, et al. Relative spatial positions of tryptophan and cationic residues in helical membrane-active peptides determine their cytotoxicity. J Biol Chem. 2012;287(1):233-244.
-
(2012)
J Biol Chem
, vol.287
, Issue.1
, pp. 233-244
-
-
Rekdal, Ø.1
Haug, B.E.2
Kalaaji, M.3
-
55
-
-
84874483568
-
Mechanism of action and initial evaluation of a membrane active all-D-enantiomer antimicrobial peptidomimetic
-
McGrath DM, Barbu EM, Driessen WH, et al. Mechanism of action and initial evaluation of a membrane active all-D-enantiomer antimicrobial peptidomimetic. Proc Natl Acad Sci U S A. 2013;110(9): 3477-3482.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.9
, pp. 3477-3482
-
-
McGrath, D.M.1
Barbu, E.M.2
Driessen, W.H.3
-
56
-
-
84884829581
-
An antimicrobial peptidomimetic induces Mucorales cell death through mitochondria-mediated apoptosis
-
Barbu EM, Shirazi F, McGrath DM, et al. An antimicrobial peptidomimetic induces Mucorales cell death through mitochondria-mediated apoptosis. PLoS One. 2013;8(10):e76981.
-
(2013)
PLoS One
, vol.8
, Issue.10
-
-
Barbu, E.M.1
Shirazi, F.2
McGrath, D.M.3
-
57
-
-
47749116861
-
Synthetic antimicrobial peptidomimetics with therapeutic potential
-
Haug BE, Stensen W, Kalaaji M, Rekdal Ø, Svendsen JS. Synthetic antimicrobial peptidomimetics with therapeutic potential. J Med Chem. 2008;51(14):4306-4314.
-
(2008)
J Med Chem
, vol.51
, Issue.14
, pp. 4306-4314
-
-
Haug, B.E.1
Stensen, W.2
Kalaaji, M.3
Rekdal, Ø.4
Svendsen, J.S.5
-
58
-
-
33744460279
-
Proteomimetic libraries: Design, synthesis, and evaluation of p53-MDM2 interaction inhibitors
-
Lu F, Chi SW, Kim DH, Han KH, Kuntz ID, Guy RK. Proteomimetic libraries: design, synthesis, and evaluation of p53-MDM2 interaction inhibitors. J Comb Chem. 2006;8(3):315-325.
-
(2006)
J Comb Chem
, vol.8
, Issue.3
, pp. 315-325
-
-
Lu, F.1
Chi, S.W.2
Kim, D.H.3
Han, K.H.4
Kuntz, I.D.5
Guy, R.K.6
-
59
-
-
84867383554
-
Recent development of small antimicrobial peptidomimetics
-
Niu Y, Wang RE, Wu H, Cai J. Recent development of small antimicrobial peptidomimetics. Future Med Chem. 2012;4(14):1853-1862.
-
(2012)
Future Med Chem
, vol.4
, Issue.14
, pp. 1853-1862
-
-
Niu, Y.1
Wang, R.E.2
Wu, H.3
Cai, J.4
-
60
-
-
66349107098
-
De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers
-
Choi S, Isaacs A, Clements D, et al. De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers. Proc Natl Acad Sci U S A. 2009;106(17):6968-6973.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.17
, pp. 6968-6973
-
-
Choi, S.1
Isaacs, A.2
Clements, D.3
-
61
-
-
84907870736
-
-
Polymedix, Inc. Brilacidin (PMX-30063) Antibiotic Fact Sheet. Randor, PA: PolyMedix, Inc, Available from
-
Polymedix, Inc. Brilacidin (PMX-30063) Antibiotic Fact Sheet. Randor, PA: PolyMedix, Inc.; 2013. Available from: http://files.shareholder.com/downloads/ABEA-4ITCYZ/1997024712x0x611205/FEA66C67-D02F-4FF2-B230-AA711F46ED7F/PMX-30063_Antibiotic_Fact_Sheet_Nov_2012_pdf. Accessed February 10, 2013.
-
(2013)
-
-
-
62
-
-
0033040696
-
The implication of the chemokine receptor CXCR4 in HIV-1 envelope protein-induced apoptosis is independent of the G protein-mediated signalling
-
Blanco J, Jacotot E, Cabrera C, et al. The implication of the chemokine receptor CXCR4 in HIV-1 envelope protein-induced apoptosis is independent of the G protein-mediated signalling. AIDS. 1999;13(8): 909-917.
-
(1999)
AIDS
, vol.13
, Issue.8
, pp. 909-917
-
-
Blanco, J.1
Jacotot, E.2
Cabrera, C.3
-
63
-
-
84870008010
-
CXCR4 stimulates macropinocytosis: Implications for cellular uptake of arginine-rich cell-penetrating peptides and HIV
-
Tanaka G, Nakase I, Fukuda Y, et al. CXCR4 stimulates macropinocytosis: implications for cellular uptake of arginine-rich cell-penetrating peptides and HIV. Chem Biol. 2012;19(11): 1437-1446.
-
(2012)
Chem Biol
, vol.19
, Issue.11
, pp. 1437-1446
-
-
Tanaka, G.1
Nakase, I.2
Fukuda, Y.3
-
64
-
-
28944452573
-
The therapeutic potential of CXCR4 antagonists in the treatment of HIV infection, cancer metastasis and rheumatoid arthritis
-
Tamamura H, Fujii N. The therapeutic potential of CXCR4 antagonists in the treatment of HIV infection, cancer metastasis and rheumatoid arthritis. Expert Opin Ther Targets. 2005;9(6):1267-1282.
-
(2005)
Expert Opin Ther Targets
, vol.9
, Issue.6
, pp. 1267-1282
-
-
Tamamura, H.1
Fujii, N.2
-
65
-
-
34247509368
-
Therapeutic potential of the chemokine receptor CXCR4 antagonists as multifunctional agents
-
Tsutsumi H, Tanaka T, Ohashi N, et al. Therapeutic potential of the chemokine receptor CXCR4 antagonists as multifunctional agents. Biopolymers. 2007;88(2):279-289.
-
(2007)
Biopolymers
, vol.88
, Issue.2
, pp. 279-289
-
-
Tsutsumi, H.1
Tanaka, T.2
Ohashi, N.3
-
66
-
-
33846002362
-
Development of low molecular weight CXCR4 antagonists by exploratory structural tuning of cyclic tetra-and pentapeptide-scaffolds towards the treatment of HIV infection, cancer metastasis and rheumatoid arthritis
-
Tamamura H, Tsutsumi H, Masuno H, Fujii N. Development of low molecular weight CXCR4 antagonists by exploratory structural tuning of cyclic tetra-and pentapeptide-scaffolds towards the treatment of HIV infection, cancer metastasis and rheumatoid arthritis. Curr Med Chem. 2007;14(1):93-102.
-
(2007)
Curr Med Chem
, vol.14
, Issue.1
, pp. 93-102
-
-
Tamamura, H.1
Tsutsumi, H.2
Masuno, H.3
Fujii, N.4
-
67
-
-
41149151814
-
Anti-HIV activity and resistance profile of the CXC chemokine receptor 4 antagonist POL3026
-
Moncunill G, Armand-Ugón M, Clotet-Codina I, et al. Anti-HIV activity and resistance profile of the CXC chemokine receptor 4 antagonist POL3026. Mol Pharmacol. 2008;73(4):1264-1273.
-
(2008)
Mol Pharmacol
, vol.73
, Issue.4
, pp. 1264-1273
-
-
Moncunill, G.1
Armand-Ugón, M.2
Clotet-Codina, I.3
-
68
-
-
29744432220
-
Unique ligand binding sites on CXCR4 probed by a chemical biology approach: Implications for the design of selective human immunodeficiency virus type 1 inhibitors
-
Choi WT, Tian S, Dong CZ, et al. Unique ligand binding sites on CXCR4 probed by a chemical biology approach: implications for the design of selective human immunodeficiency virus type 1 inhibitors. J Virol. 2005;79(24):15398-15404.
-
(2005)
J Virol
, vol.79
, Issue.24
, pp. 15398-15404
-
-
Choi, W.T.1
Tian, S.2
Dong, C.Z.3
-
69
-
-
84861048825
-
Structure-based design, synthesis, and characterization of dual hotspot small-molecule HIV-1 entry inhibitors
-
LaLonde JM, Kwon YD, Jones DM, et al. Structure-based design, synthesis, and characterization of dual hotspot small-molecule HIV-1 entry inhibitors. J Med Chem. 2012;55(9):4382-4396.
-
(2012)
J Med Chem
, vol.55
, Issue.9
, pp. 4382-4396
-
-
Lalonde, J.M.1
Kwon, Y.D.2
Jones, D.M.3
-
70
-
-
0033590169
-
Glycans and proteoglycans are involved in the interactions of human immunodeficiency virus type 1 envelope glycoprotein and of SDF-1alpha with membrane ligands of CD4(+) CXCR4(+) cells
-
Mbemba E, Benjouad A, Saffar L, Gattegno L. Glycans and proteoglycans are involved in the interactions of human immunodeficiency virus type 1 envelope glycoprotein and of SDF-1alpha with membrane ligands of CD4(+) CXCR4(+) cells. Virology. 1999;265(2):354-364.
-
(1999)
Virology
, vol.265
, Issue.2
, pp. 354-364
-
-
Mbemba, E.1
Benjouad, A.2
Saffar, L.3
Gattegno, L.4
-
71
-
-
69549114617
-
Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold: The exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids
-
Tanaka T, Nomura W, Narumi T, et al. Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold: the exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids. Org Biomol Chem. 2009;7(18):3805-3809.
-
(2009)
Org Biomol Chem
, vol.7
, Issue.18
, pp. 3805-3809
-
-
Tanaka, T.1
Nomura, W.2
Narumi, T.3
-
72
-
-
80455162590
-
Design, synthesis, and functionalization of dimeric peptides targeting chemokine receptor CXCR4
-
Demmer O, Dijkgraaf I, Schumacher U, et al. Design, synthesis, and functionalization of dimeric peptides targeting chemokine receptor CXCR4. J Med Chem. 2011;54(21):7648-7662.
-
(2011)
J Med Chem
, vol.54
, Issue.21
, pp. 7648-7662
-
-
Demmer, O.1
Dijkgraaf, I.2
Schumacher, U.3
-
73
-
-
78649673542
-
The peptidomimetic CXCR4 antagonist TC14012 recruits beta-arrestin to CXCR7: Roles of receptor domains
-
Gravel S, Malouf C, Boulais PE, et al. The peptidomimetic CXCR4 antagonist TC14012 recruits beta-arrestin to CXCR7: roles of receptor domains. J Biol Chem. 2010;285(49):37939-37943.
-
(2010)
J Biol Chem
, vol.285
, Issue.49
, pp. 37939-37943
-
-
Gravel, S.1
Malouf, C.2
Boulais, P.E.3
-
74
-
-
77952813636
-
Targeting SDF-1/CXCL12 with a ligand that prevents activation of CXCR4 through structure-based drug design
-
Veldkamp CT, Ziarek JJ, Peterson FC, Chen Y, Volkman BF. Targeting SDF-1/CXCL12 with a ligand that prevents activation of CXCR4 through structure-based drug design. J Am Chem Soc. 2010;132(21):7242-7243.
-
(2010)
J Am Chem Soc
, vol.132
, Issue.21
, pp. 7242-7243
-
-
Veldkamp, C.T.1
Ziarek, J.J.2
Peterson, F.C.3
Chen, Y.4
Volkman, B.F.5
-
75
-
-
0029911702
-
Anti-human immunodeficiency virus type 1 activity of an oligocationic compound mediated via gp120 V3 interactions
-
O’Brien WA, Sumner-Smith M, Mao SH, Sadeghi S, Zhao JQ, Chen IS. Anti-human immunodeficiency virus type 1 activity of an oligocationic compound mediated via gp120 V3 interactions. J Virol. 1996;70(5):2825-2831.
-
(1996)
J Virol
, vol.70
, Issue.5
, pp. 2825-2831
-
-
O’brien, W.A.1
Sumner-Smith, M.2
Mao, S.H.3
Sadeghi, S.4
Zhao, J.Q.5
Chen, I.S.6
-
76
-
-
0030773515
-
A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor
-
Doranz BJ, Grovit-Ferbas K, Sharron MP, et al. A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor. J Exp Med. 1997;186(8):1395-1400.
-
(1997)
J Exp Med
, vol.186
, Issue.8
, pp. 1395-1400
-
-
Doranz, B.J.1
Grovit-Ferbas, K.2
Sharron, M.P.3
-
77
-
-
0347627799
-
The N-terminal domain of APJ, a CNS-based coreceptor for HIV-1, is essential for its receptor function and coreceptor activity
-
Zhou N, Zhang X, Fan X, et al. The N-terminal domain of APJ, a CNS-based coreceptor for HIV-1, is essential for its receptor function and coreceptor activity. Virology. 2003;317(1):84-94.
-
(2003)
Virology
, vol.317
, Issue.1
, pp. 84-94
-
-
Zhou, N.1
Zhang, X.2
Fan, X.3
-
78
-
-
84874954823
-
Antiviral peptide nanocomplexes as a potential therapeutic modality for HIV/HCV co-infection
-
Zhang J, Mulvenon A, Makarov E, et al. Antiviral peptide nanocomplexes as a potential therapeutic modality for HIV/HCV co-infection. Biomaterials. 2013;34(15):3846-3857.
-
(2013)
Biomaterials
, vol.34
, Issue.15
, pp. 3846-3857
-
-
Zhang, J.1
Mulvenon, A.2
Makarov, E.3
-
79
-
-
33644775686
-
Targeting multidrug resistance in cancer
-
Szakács G, Paterson JK, Ludwig JA, Booth-Genthe C, Gottesman MM. Targeting multidrug resistance in cancer. Nat Rev Drug Discov. 2006;5(3):219-234.
-
(2006)
Nat Rev Drug Discov
, vol.5
, Issue.3
, pp. 219-234
-
-
Szakács, G.1
Paterson, J.K.2
Ludwig, J.A.3
Booth-Genthe, C.4
Gottesman, M.M.5
-
80
-
-
38349009178
-
Studies on anticancer activities of antimicrobial peptides
-
Hoskin DW, Ramamoorthy A. Studies on anticancer activities of antimicrobial peptides. Biochim Biophys Acta. 2008;1778(2):357-375.
-
(2008)
Biochim Biophys Acta
, vol.1778
, Issue.2
, pp. 357-375
-
-
Hoskin, D.W.1
Ramamoorthy, A.2
-
81
-
-
79951664559
-
The cyclic pentapeptide d-Arg3FC131, a CXCR4 antagonist, induces apoptosis of somatotrope tumor and inhibits tumor growth in nude mice
-
Kim JM, Lee YH, Ku CR, Lee EJ. The cyclic pentapeptide d-Arg3FC131, a CXCR4 antagonist, induces apoptosis of somatotrope tumor and inhibits tumor growth in nude mice. Endocrinology. 2011;152(2):536-544.
-
(2011)
Endocrinology
, vol.152
, Issue.2
, pp. 536-544
-
-
Kim, J.M.1
Lee, Y.H.2
Ku, C.R.3
Lee, E.J.4
-
82
-
-
84888199077
-
Different CXCR4 expression according to various histologic subtype of papillary thyroid carcinoma
-
Shin DY, Kim KJ, Ku CR, et al. Different CXCR4 expression according to various histologic subtype of papillary thyroid carcinoma. Endocr Pathol. 2013;24(4):169-176.
-
(2013)
Endocr Pathol
, vol.24
, Issue.4
, pp. 169-176
-
-
Shin, D.Y.1
Kim, K.J.2
Ku, C.R.3
-
84
-
-
18544366816
-
Host defense peptides as new weapons in cancer treatment
-
Papo N, Shai Y. Host defense peptides as new weapons in cancer treatment. Cell Mol Life Sci. 2005;62(7-8):784-790.
-
(2005)
Cell Mol Life Sci
, vol.62
, Issue.7-8
, pp. 784-790
-
-
Papo, N.1
Shai, Y.2
-
85
-
-
71749100398
-
Cationic amphiphilic peptides with cancer-selective toxicity
-
Schweizer F. Cationic amphiphilic peptides with cancer-selective toxicity. Eur J Pharmacol. 2009;625(1-3):190-194.
-
(2009)
Eur J Pharmacol
, vol.625
, Issue.1-3
, pp. 190-194
-
-
Schweizer, F.1
-
86
-
-
38649129118
-
An oxazole-based small-molecule Stat3 inhibitor modulates Stat3 stability and processing and induces antitumor cell effects
-
Siddiquee KA, Gunning PT, Glenn M, et al. An oxazole-based small-molecule Stat3 inhibitor modulates Stat3 stability and processing and induces antitumor cell effects. ACS Chem Biol. 2007;2(12):787-798.
-
(2007)
ACS Chem Biol
, vol.2
, Issue.12
, pp. 787-798
-
-
Siddiquee, K.A.1
Gunning, P.T.2
Glenn, M.3
-
87
-
-
78649887035
-
Drug delivery to solid tumors by elastin-like polypeptides
-
McDaniel JR, Callahan DJ, Chilkoti A. Drug delivery to solid tumors by elastin-like polypeptides. Adv Drug Deliv Rev. 2010;62(15): 1456-1467.
-
(2010)
Adv Drug Deliv Rev
, vol.62
, Issue.15
, pp. 1456-1467
-
-
McDaniel, J.R.1
Callahan, D.J.2
Chilkoti, A.3
-
88
-
-
84862678916
-
Encapsulation of new active ingredients
-
Onwulata CI. Encapsulation of new active ingredients. Annu Rev Food Sci Technol. 2012;3:183-202.
-
(2012)
Annu Rev Food Sci Technol
, vol.3
, pp. 183-202
-
-
Onwulata, C.I.1
-
89
-
-
84879256005
-
Separation, antitumor activities, and encapsulation of polypeptide from Chlorella pyrenoidosa
-
Wang X, Zhang X. Separation, antitumor activities, and encapsulation of polypeptide from Chlorella pyrenoidosa. Biotechnol Prog. 2013;29(3):681-687.
-
(2013)
Biotechnol Prog
, vol.29
, Issue.3
, pp. 681-687
-
-
Wang, X.1
Zhang, X.2
-
90
-
-
84872241048
-
Antitumor activity of antimicrobial peptides containing CisoDGRC in CD13 negative breast cancer cells
-
Hou L, Zhao X, Wang P, Ning Q, Meng M, Liu C. Antitumor activity of antimicrobial peptides containing CisoDGRC in CD13 negative breast cancer cells. PLoS One. 2013;8(1):e53491.
-
(2013)
PLoS One
, vol.8
, Issue.1
-
-
Hou, L.1
Zhao, X.2
Wang, P.3
Ning, Q.4
Meng, M.5
Liu, C.6
-
91
-
-
84871547634
-
Analgesic-antitumor peptide induces apoptosis and inhibits the proliferation of SW480 human colon cancer cells
-
Gu Y, Liu SL, Ju WZ, Li CY, Cao P. Analgesic-antitumor peptide induces apoptosis and inhibits the proliferation of SW480 human colon cancer cells. Oncol Lett. 2013;5(2):483-488.
-
(2013)
Oncol Lett
, vol.5
, Issue.2
, pp. 483-488
-
-
Gu, Y.1
Liu, S.L.2
Ju, W.Z.3
Li, C.Y.4
Cao, P.5
|