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Volumn 152, Issue 2, 2011, Pages 536-544

The cyclic pentapeptide d-arg3FC131, a CXCR4 antagonist, induces apoptosis of somatotrope tumor and inhibits tumor growth in nude mice

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; D ARG3FC131 PEPTIDE; GROWTH HORMONE; UNCLASSIFIED DRUG;

EID: 79951664559     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2010-0642     Document Type: Article
Times cited : (23)

References (39)
  • 1
    • 33845491265 scopus 로고    scopus 로고
    • Medical progress: Acromegaly
    • Melmed S 2006 Medical progress: Acromegaly. N Engl J Med 355:2558-2573
    • (2006) N Engl J Med , vol.355 , pp. 2558-2573
    • Melmed, S.1
  • 2
    • 1442326975 scopus 로고    scopus 로고
    • Systemic Complications of Acromegaly: Epidemiology, Pathogenesis, and Management
    • DOI 10.1210/er.2002-0022
    • Colao A, Ferone D, Marzullo P, Lombardi G 2004 Systemic complications of acromegaly: epidemiology, pathogenesis, and management. Endocr Rev 25:102-152 (Pubitemid 38269977)
    • (2004) Endocrine Reviews , vol.25 , Issue.1 , pp. 102-152
    • Colao, A.1    Ferone, D.2    Marzullo, P.3    Lombardi, G.4
  • 3
    • 33745022151 scopus 로고    scopus 로고
    • Newer options in the management of acromegaly
    • DOI 10.1111/j.1445-5994.2006.01097.x
    • Burt MG, Ho KK 2006 Newer options in the management of acromegaly. Intern Med J 36:437-444 (Pubitemid 43876238)
    • (2006) Internal Medicine Journal , vol.36 , Issue.7 , pp. 437-444
    • Burt, M.G.1    Ho, K.K.Y.2
  • 5
    • 18744389775 scopus 로고    scopus 로고
    • Combined therapy with somatostatin analogues and weekly pegvisomant in active acromegaly
    • DOI 10.1016/S0140-6736(05)63011-5, PII S0140673605630115
    • Feenstra J, de Herder WW, ten Have SM, van den Beld AW, Feelders RA, Janssen JA, van der Lely AJ 2005 Combined therapy with somatostatin analogues and weekly pegvisomant in active acromegaly. Lancet 365:1644-1646 (Pubitemid 40693415)
    • (2005) Lancet , vol.365 , Issue.9471 , pp. 1644-1646
    • Feenstra, J.1    De, H.W.W.2    Ten, H.S.M.T.H.3    Van, D.B.A.W.4    Feelders, R.A.5    Janssen, J.A.M.J.L.6    Van, D.L.A.J.7
  • 6
    • 69949142355 scopus 로고    scopus 로고
    • A randomized, controlled, multicentre trial comparing pegvisomant alone with combination therapy of pegvisomant and long-acting octreotide in patients with acromegaly
    • Oxf
    • Trainer PJ, Ezzat S, D'Souza GA, Layton G, Strasburger CJ 2009 A randomized, controlled, multicentre trial comparing pegvisomant alone with combination therapy of pegvisomant and long-acting octreotide in patients with acromegaly. Clin Endocrinol (Oxf) 71:549-557
    • (2009) Clin Endocrinol , vol.71 , pp. 549-557
    • Trainer, P.J.1    Ezzat, S.2    D'Souza, G.A.3    Layton, G.4    Strasburger, C.J.5
  • 9
    • 0031975540 scopus 로고    scopus 로고
    • Identification and characterization of the CXCR4 chemokine receptor in human T cell lines: Ligand binding, biological activity, and HIV-1 infectivity
    • Hesselgesser J, Liang M, Hoxie J, Greenberg M, Brass LF, Orsini MJ, Taub D, Horuk R 1998 Identification and characterization of the CXCR4 chemokine receptor in human T cell lines: ligand binding, biological activity, and HIV-1 infectivity. J Immunol 160:877-883 (Pubitemid 28049330)
    • (1998) Journal of Immunology , vol.160 , Issue.2 , pp. 877-883
    • Hesselgesser, J.1    Liang, M.2    Hoxie, J.3    Greenberg, M.4    Brass, L.F.5    Orsini, M.J.6    Taub, D.7    Horuk, R.8
  • 10
    • 0034544508 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1-CXC chemokine receptor 4 interactions play a central role in CD4+ T cell accumulation in rheumatoid arthritis synovium
    • Nanki T, Hayashida K, El-Gabalawy HS, Suson S, Shi K, Girschick HJ, Yavuz S, Lipsky PE 2000 Stromal cell-derived factor-1-CXC chemokine receptor 4 interactions play a central role in CD4+ T cell accumulation in rheumatoid arthritis synovium. J Immunol 165:6590-6598
    • (2000) J Immunol , vol.165 , pp. 6590-6598
    • Nanki, T.1    Hayashida, K.2    El-Gabalawy, H.S.3    Suson, S.4    Shi, K.5    Girschick, H.J.6    Yavuz, S.7    Lipsky, P.E.8
  • 11
    • 0037082510 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1 regulates primitive hematopoiesis by suppressing apoptosis and by promoting G(0)/G(1) transition in CD34(+) cells: Evidence for an autocrine/paracrine mechanism
    • Lataillade JJ, Clay D, Bourin P, Hérodin F, Dupuy C, Jasmin C, Le Bousse-Kerdilès MC 2002 Stromal cell-derived factor 1 regulates primitive hematopoiesis by suppressing apoptosis and by promoting G(0)/G(1) transition in CD34(+) cells: evidence for an autocrine/paracrine mechanism. Blood 99:1117-1129
    • (2002) Blood , vol.99 , pp. 1117-1129
    • Lataillade, J.J.1    Clay, D.2    Bourin, P.3    Hérodin, F.4    Dupuy, C.5    Jasmin, C.6    Le Bousse-Kerdilès, M.C.7
  • 13
    • 0027165675 scopus 로고
    • Signal sequence trap: A cloning strategy for secreted proteins and type I membrane proteins
    • Tashiro K, Tada H, Heilker R, Shirozu M, Nakano T, Honjo T 1993 Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins. Science 261:600-603 (Pubitemid 23278369)
    • (1993) Science , vol.261 , Issue.5121 , pp. 600-603
    • Tashiro, K.1    Tada, H.2    Heilker, R.3    Shirozu, M.4    Nakano, T.5    Honjo, T.6
  • 14
    • 36749003738 scopus 로고    scopus 로고
    • Involvement of SDF-1α/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma
    • DOI 10.1002/ijc.23083
    • Kajiyama H, Shibata K, Terauchi M, Ino K, Nawa A, Kikkawa F 2008 Involvement of SDF-1α/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma. Int J Cancer 122:91-99 (Pubitemid 350209982)
    • (2008) International Journal of Cancer , vol.122 , Issue.1 , pp. 91-99
    • Kajiyama, H.1    Shibata, K.2    Terauchi, M.3    Ino, K.4    Nawa, A.5    Kikkawa, F.6
  • 15
    • 34548710861 scopus 로고    scopus 로고
    • Migration of endothelial progenitor cells mediated by stromal cell-derived factor-1α/CXCR4 via PI3K/Akt/eNOS signal transduction pathway
    • DOI 10.1097/FJC.0b013e318093ec8f, PII 0000534420070900000008
    • Zheng H, Fu G, Dai T, Huang H 2007 Migration of endothelial progenitor cells mediated by stromal cell-derived factor-1α/CXCR4 via PI3K/Akt/eNOS signal transduction pathway. J Cardiovasc Pharmacol 50:274-280 (Pubitemid 47428975)
    • (2007) Journal of Cardiovascular Pharmacology , vol.50 , Issue.3 , pp. 274-280
    • Zheng, H.1    Fu, G.2    Dai, T.3    Huang, H.4
  • 20
    • 0141705319 scopus 로고    scopus 로고
    • Highly regionalized distribution of stromal cell-derived factor-1/CXCL12 in adult rat brain: constitutive expression in cholinergic, dopaminergic and vasopressinergic neurons
    • Banisadr G, Skrzydelski D, Kitabgi P, Rostène W, Parsadaniantz SM 2003 Highly regionalized distribution of stromal cell-derived factor-1/CXCL12 in adult rat brain: constitutive expression in cholinergic, dopaminergic and vasopressinergic neurons. Eur J Neurosci 18:1593-1606
    • (2003) Eur J Neurosci , vol.18 , pp. 1593-1606
    • Banisadr, G.1    Skrzydelski, D.2    Kitabgi, P.3    Rostène, W.4    Parsadaniantz, S.M.5
  • 21
    • 37549028470 scopus 로고    scopus 로고
    • Cellular and subcellular evidence for neuronal interaction between the chemokine stromal cell-derived factor-1/CXCL 12 and vasopressin: Regulation in the hypothalamo-neurohypophysial system of the Brattleboro rats
    • Callewaere C, Fernette B, Raison D, Mechighel P, Burlet A, Calas A, Kitabgi P, Parsadaniantz SM, Rostène W 2008 Cellular and subcellular evidence for neuronal interaction between the chemokine stromal cell-derived factor-1/CXCL 12 and vasopressin: regulation in the hypothalamo-neurohypophysial system of the Brattleboro rats. Endocrinology 149:310-319
    • (2008) Endocrinology , vol.149 , pp. 310-319
    • Callewaere, C.1    Fernette, B.2    Raison, D.3    Mechighel, P.4    Burlet, A.5    Calas, A.6    Kitabgi, P.7    Parsadaniantz, S.M.8    Rostène, W.9
  • 22
    • 56849112798 scopus 로고    scopus 로고
    • Functional expression of CXCR4 in somatotrophs: CXCL12 activates GH gene, GH production and secretion, and cellular proliferation
    • Lee Y, Kim JM, Lee EJ 2008 Functional expression of CXCR4 in somatotrophs: CXCL12 activates GH gene, GH production and secretion, and cellular proliferation. J Endocrinol 199:191-199
    • (2008) J Endocrinol , vol.199 , pp. 191-199
    • Lee, Y.1    Kim, J.M.2    Lee, E.J.3
  • 23
  • 25
    • 0034606466 scopus 로고    scopus 로고
    • Pharmacophore identification of a specific CXCR4 inhibitor, T140, leads to development of effective anti-HIV agents with very high selectivity indexes
    • Tamamura H, Omagari A, Oishi S, Kanamoto T, Yamamoto N, Peiper SC, Nakashima H, Otaka A, Fujii N 2000 Pharmacophore identification of a specific CXCR4 inhibitor, T140, leads to development of effective anti-HIV agents with very high selectivity indexes. Bioorg Med Chem Lett 10:2633-2637
    • (2000) Bioorg Med Chem Lett , vol.10 , pp. 2633-2637
    • Tamamura, H.1    Omagari, A.2    Oishi, S.3    Kanamoto, T.4    Yamamoto, N.5    Peiper, S.C.6    Nakashima, H.7    Otaka, A.8    Fujii, N.9
  • 29
    • 0035116831 scopus 로고    scopus 로고
    • Restoration of growth hormone-releasing hormone (GHRH) responsiveness in pituitary GH3 cells by adenovirus-directed expression of the human GHRH receptor
    • DOI 10.1210/en.142.1.414
    • Lee EJ, Duan WR, Kotlar T, Jameson JL 2001 Restoration of growth hormone-releasing hormone (GHRH) responsiveness in pituitary GH3 cells by adenovirus-directed expression of the human GHRH receptor. Endocrinology 142:414-420 (Pubitemid 32183703)
    • (2001) Endocrinology , vol.142 , Issue.1 , pp. 414-420
    • Lee, E.J.1    Duan, W.R.2    Kotlar, T.O.M.3    Jameson, J.L.4
  • 31
    • 0032979226 scopus 로고    scopus 로고
    • Targeted expression of toxic genes directed by pituitary hormone promoters: A potential strategy for adenovirus-mediated gene therapy of pituitary tumors
    • DOI 10.1210/jc.84.2.786
    • Lee EJ, Anderson LM, Thimmapaya B, Jameson JL 1999 Targeted expression of toxic genes directed by pituitary hormone promoters: a potential strategy for adenovirus-mediated gene therapy of pituitary tumors. J Clin Endocrinol Metab 84:786-794 (Pubitemid 29075722)
    • (1999) Journal of Clinical Endocrinology and Metabolism , vol.84 , Issue.2 , pp. 786-794
    • Lee, E.J.1    Anderson, L.M.2    Thimmapaya, B.3    Jameson, J.L.4
  • 32
    • 0028982707 scopus 로고
    • Somatostatin-14 and its analog octreotide exert a cytostatic effect on GH3 rat pituitary tumor cell proliferation via a transient G0/G1 cell cycle block
    • Cheung NW, Boyages SC 1995 Somatostatin-14 and its analog octreotide exert a cytostatic effect on GH3 rat pituitary tumor cell proliferation via a transient G0/G1 cell cycle block. Endocrinology 136:4174-4181
    • (1995) Endocrinology , vol.136 , pp. 4174-4181
    • Cheung, N.W.1    Boyages, S.C.2
  • 33
    • 4544379049 scopus 로고    scopus 로고
    • Nonhomologous end-joining ligation transfers DNA regulatory elements between cointroduced plasmids
    • DOI 10.1128/MCB.24.19.8323-8331.2004
    • Ishikawa T, Lee EJ, Jameson JL 2004 Nonhomologous end-joining ligation transfers DNA regulatory elements between cointroduced plasmids. Mol Cell Biol 24:8323-8331 (Pubitemid 39245055)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.19 , pp. 8323-8331
    • Ishikawa, T.1    Lee, E.J.2    Jameson, J.L.3
  • 34
    • 0034875303 scopus 로고    scopus 로고
    • 4 pituitary lactotrope cells and inhibits tumor growth in nude mice
    • DOI 10.1210/en.142.9.3756
    • Lee EJ, Duan WR, Jakacka M, Gehm BD, Jameson JL 2001 Dominant negative ER induces apoptosis in GH(4) pituitary lactotrope cells and inhibits tumor growth in nude mice. Endocrinology 142:3756-3763 (Pubitemid 32802646)
    • (2001) Endocrinology , vol.142 , Issue.9 , pp. 3756-3763
    • Lee, E.J.1    Duan, W.R.2    Jakacka, M.3    Gehm, B.D.4    Jameson, J.L.5
  • 36
    • 33344464945 scopus 로고    scopus 로고
    • CXCR4: A key receptor in the crosstalk between tumor cells and their microenvironment
    • DOI 10.1182/blood-2005-08-3182
    • Burger JA, Kipps TJ 2006 CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment. Blood 107:1761-1767 (Pubitemid 43289351)
    • (2006) Blood , vol.107 , Issue.5 , pp. 1761-1767
    • Burger, J.A.1    Kipps, T.J.2
  • 37
    • 34250724520 scopus 로고    scopus 로고
    • The SDF-1-CXCR4 signaling pathway: A molecular hub modulating neo-angiogenesis
    • DOI 10.1016/j.it.2007.05.007, PII S1471490607001287
    • Petit I, Jin D, Rafii S 2007 The SDF-1-CXCR4 signaling pathway: a molecular hub modulating neo-angiogenesis. Trends Immunol 28:299-307 (Pubitemid 46963141)
    • (2007) Trends in Immunology , vol.28 , Issue.7 , pp. 299-307
    • Petit, I.1    Jin, D.2    Rafii, S.3
  • 38
    • 54049128151 scopus 로고    scopus 로고
    • SDF-1α/CXCR4 decreases endothelial progenitor cells apoptosis under serum deprivation by PI3K/Akt/eNOS pathway
    • Zheng H, Dai T, Zhou B, Zhu J, Huang H, Wang M, Fu G 2008 SDF-1α/CXCR4 decreases endothelial progenitor cells apoptosis under serum deprivation by PI3K/Akt/eNOS pathway. Atherosclerosis 201:36-42
    • (2008) Atherosclerosis , vol.201 , pp. 36-42
    • Zheng, H.1    Dai, T.2    Zhou, B.3    Zhu, J.4    Huang, H.5    Wang, M.6    Fu, G.7
  • 39
    • 0037218576 scopus 로고    scopus 로고
    • Transgenic expression of stromal cell-derived factor-1/CXC chemokine ligand 12 enhances myeloid progenitor cell survival/antiapoptosis in vitro in response to growth factor withdrawal and enhances myelopoiesis in vivo
    • Broxmeyer HE, Cooper S, Kohli L, Hangoc G, Lee Y, Mantel C, Clapp DW, Kim CH 2003 Transgenic expression of stromal cell-derived factor-1/CXC chemokine ligand 12 enhances myeloid progenitor cell survival/antiapoptosis in vitro in response to growth factor withdrawal and enhances myelopoiesis in vivo. J Immunol 170:421-429 (Pubitemid 36026167)
    • (2003) Journal of Immunology , vol.170 , Issue.1 , pp. 421-429
    • Broxmeyer, H.E.1    Cooper, S.2    Kohli, L.3    Hangoc, G.4    Lee, Y.5    Mantel, C.6    Clapp, D.W.7    Kim, C.H.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.