Leptin as an uremic toxin: Deleterious role of leptin in chronic kidney disease

Biochimie

Volumn 105, Issue , 2014, Pages 12-21

  Alix, Pascaline M ^a,b   Guebre Egziabher, Fitsum ^a,b   Soulage, Christophe O ^a  

^a UNIVERSITÉ LYON 1   (France)

^b EDOUARD HERRIOT HOSPITAL   (France)

Author keywords

Chronic kidney disease; Leptin; Protein energy wasting; Renal fibrosis; Uremic toxin

Indexed keywords

C REACTIVE PROTEIN; HORMONE ANTAGONIST; HORMONE RECEPTOR BLOCKING AGENT; INSULIN; LEPTIN; LEPTIN ANTAGONIST; LEPTIN RECEPTOR; MEGALIN; MELANOCORTIN 4 RECEPTOR; MELANOCORTIN RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG; UREMIC TOXIN; TOXIN;

ATHEROSCLEROTIC CARDIOVASCULAR DISEASE; BACTERIAL INFECTION; BLOOD VESSEL CALCIFICATION; BONE METABOLISM; BONE REMODELING; CACHEXIA; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CARDIOVASCULAR SYSTEM; CHRONIC INFLAMMATION; CHRONIC KIDNEY DISEASE; CLINICAL TRIAL (TOPIC); DISEASE COURSE; END STAGE RENAL DISEASE; EXPERIMENTAL MODEL; FAT MASS; GLOMERULOSCLEROSIS; HEMATOPOIESIS; HEMODIAFILTRATION; HEMODIALYSIS; HORMONE RELEASE; HORMONE SYNTHESIS; HUMAN; HYPERINSULINEMIA; HYPERLEPTINEMIA; HYPERTENSION; IMMUNE SYSTEM; IMMUNITY; IN VITRO STUDY; INSULIN RESISTANCE; KIDNEY CLEARANCE; KIDNEY TRANSPLANTATION; METABOLIC BONE DISEASE; MUSCLE ATROPHY; NEGATIVE FEEDBACK; NONHUMAN; PATHOGENESIS; PEGYLATED LEPTIN RECEPTOR ANTAGONIST; PERITONEAL DIALYSIS; PROTEIN CALORIE MALNUTRITION; RANDOMIZED CONTROLLED TRIAL (TOPIC); REGULATORY MECHANISM; REVIEW; THROMBOCYTE DYSFUNCTION; THROMBOSIS; UREMIA; WHITE ADIPOSE TISSUE; ADIPOSE TISSUE; CHEMISTRY; CHRONIC KIDNEY FAILURE; GENETICS; INFLAMMATION; METABOLISM; PATHOLOGY; SECRETION (PROCESS);

ADIPOSE TISSUE; CACHEXIA; HUMANS; HYPERTENSION; INFLAMMATION; INSULIN RESISTANCE; LEPTIN; RECEPTORS, LEPTIN; RENAL INSUFFICIENCY, CHRONIC; TOXINS, BIOLOGICAL;

EID: 84907856242     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2014.06.024     Document Type: Review

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