Effective removal of leptin via hemodiafiltration with on-line endogenous reinfusion therapy

Clinical Nephrology

Volumn 72, Issue 6, 2009, Pages 442-448

  Kim, S ^a,b   Oh, K H ^b,c   Chin, H J ^b   Na, K Y ^b   Kim, Y S ^b   Chae, D W ^b   Ahn, C ^b,c   Han, J S ^b   Joo, K W ^b  

^a Gachon University College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

^c Transplantation Research Institute   (South Korea)

Author keywords

End stage kidney disease; Hemodiafiltration; Hemodialysis; Leptin; 2 microglobulin

Indexed keywords

ADIPONECTIN; ALBUMIN; BETA 2 MICROGLOBULIN; C REACTIVE PROTEIN; HEMOGLOBIN; INTERLEUKIN 6; LEPTIN; NITROGEN; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; RECOMBINANT ERYTHROPOIETIN; UREA;

ADULT; AGED; ALBUMIN BLOOD LEVEL; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRY WEIGHT; HEMODIAFILTRATION; HEMODIALYSIS; HUMAN; INTERMETHOD COMPARISON; KIDNEY FAILURE; LOW FLUX HEMODIALYSIS; PROTEIN BLOOD LEVEL; THERAPY EFFECT; TREATMENT DURATION;

EID: 71449083104     PISSN: 03010430     EISSN: None     Source Type: Journal    
DOI: 10.5414/cnp72442     Document Type: Article

References (36)

1. Arita Y, Kihara S, Ouchi N et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun. 1999; 257: 79-83.
2. Beltowski J. Leptin and atherosclerosis. Atherosclerosis. 2006; 189: 47-60.
3. Bolasco PG, Ghezzi PM, Ferrara R et al. Effect of on-line hemodiafiltration with endogenous reinfusion (HFR) on the calcium-phosphorus metabolism: medium-term effects. Int J Artif Organs. 2006; 29: 1042-1052.
4. Bossola M, Muscaritoli M, Tazza L et al. Switch from bicarbonate hemodialysis to hemodiafiltration with online regeneration of the ultrafiltrate (HFR): effects on nutritional status, microinflammation, and β-microglobulin. Artif Organs. 2005; 29: 259-263.
5. Bossola M, Muscaritoli M, Valenza V et al. Anorexia and serum leptin levels in hemodialysis patients. Nephron Clin Pract. 2004; 97: 76-82.
6. Christensson L, Unosson M and Ek AC. Evaluation of nutritional assessment techniques in elderly people newly admitted to municipal care. Eur J Clin Nutr. 2002; 56: 810-818.
7. Clark WR and Winchester JF. Middle molecules and small-molecular-weight proteins in ESRD: properties and strategies for their removal. Adv Ren Replace Ther. 2003; 10: 270-278.
8. Correia ML and Haynes WG. Leptin, obesity and cardiovascular disease. Curr Opin Nephrol Hypertens. 2004; 13: 215-223.
9. de Francisco AL, Pinera C, Heras M et al. Hemodiafiltration with on-line endogenous reinfusion. Blood Purif. 2000; 18: 231-236.
10. Esposito K, Pontillo A, Di Palo C et al. Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial. Jama. 2003; 289: 1799-1804.
11. Ghezzi PM, Gervasio R, Tessore V, Sartoris AM and Botella J. Hemodiafiltration without replacement fluid. An experimental study. Asaio J. 1992; 38: 61-65.
12. Gotch FA and Sargent JA. A mechanistic analysis of the National Cooperative Dialysis Study (NCDS). Kidney Int. 1985; 28: 526-534.
13. Horl WH. Hemodialysis membranes: interleukins, biocompatibility, andmiddlemolecules. JAmSoc Nephrol. 2002; 13 (Suppl): 62-71.
14. Huang JW, Yen CJ, Chiang HW, Hung KY, Tsai TJ and Wu KD. Adiponectin in peritoneal dialysis patients: a comparison with hemodialysis patients and subjects with normal renal function. Am J Kidney Dis. 2004; 43: 1047-1055.
15. Landt M, Ludbrook PA and Billadello JJ. Role of protein binding in renal elimination of leptin. Clin Endocrinol (Oxf). 2003; 59: 44-48.
16. Levey AS, Beto JA, Coronado BE et al. Controlling the epidemic of cardiovascular disease in chronic renal disease: what do we know? What do we need to learn? Where do we go from here? National Kidney Foundation Task Force on Cardiovascular Disease. Am J Kidney Dis. 1998; 32: 853-906.
17. Meloni C, Ghezzi PM, Cipriani S et al. One year of clinical experience in postdilution hemofiltration with online reinfusion of regenerated ultrafiltrate. Blood Purif. 2004; 22: 505-509.
18. Meloni C, Ghezzi PM, Cipriani S et al. Hemodiafiltration with post-dilution reinfusion of the regenerated ultrafiltrate: a new on-line technique. Clin Nephrol. 2005; 63: 106-112.
19. Menendez C, Baldelli R, Lage M et al. The in vitro secretion of human leptin is gender-dependent but independent of the body mass index of the donors. Eur J Endocrinol. 2000; 143: 711-714.
20. Merabet E, Dagogo-Jack S, Coyne DW et al. Increased plasma leptin concentration in end-stage renal disease. J Clin Endocrinol Metab. 1997; 82: 847-850.
21. Nordfors L, Lonnqvist F, Heimburger O, Danielsson A, Schalling M and Stenvinkel P. Low leptin gene expression and hyperleptinemia in chronic renal failure. Kidney Int. 1998; 54: 1267-1275.
22. Pajvani UB, Du X, Combs TP et al. Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity. J Biol Chem. 2003; 278: 9073-9085.
23. Pajvani UB, Hawkins M, Combs TP et al. Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity. J Biol Chem. 2004; 279: 12152-12162.
24. Panichi V, Manca-Rizza G, Paoletti S et al. Effects on inflammatory and nutritional markers of haemodiafiltration with online regeneration of ultrafiltrate (HFR) vs online haemodiafiltration: a cross-over randomized multicentre trial. Nephrol Dial Transplant. 2006; 21: 756-762.
25. Ragazzoni E, Carpani P, Agliata S et al. HFR vs. HDF-ON line: plasmatic amino acids loss evaluation. G Ital Nefrol. 2004; 21 (Suppl 30): S85-2490.
26. Satoh N, Naruse M, Usui T et al. Leptin-to-adiponectin ratio as a potential atherogenic index in obese Type 2 diabetic patients. Diabetes Care. 2004; 27: 2488-2490.
27. Soderberg S, Ahren B, Jansson JH et al. Leptin is associated with increased risk of myocardial infarction. J Intern Med. 1999; 246: 409-418.
28. Soderberg S, Stegmayr B, Ahlbeck-Glader C, Slunga-Birgander L, Ahren B and Olsson T. High leptin levels are associated with stroke. Cerebrovasc Dis. 2003; 15: 63-69.
29. Stenvinkel P, Heimburger O, Paultre F et al. Strong association between malnutrition, inflammation, and atherosclerosis in chronic renal failure. Kidney Int. 1999; 55: 1899-1911.
30. Ward RA, Schmidt B, Hullin J, Hillebrand GF and Samtleben W. A comparison of on-line hemodiafiltration and high-flux hemodialysis: a prospective clinical study. J Am Soc Nephrol. 2000; 11: 2344-2350.
31. Werner N and Nickenig G. From fat fighter to risk factor: the zigzag trek of leptin. Arterioscler Thromb Vasc Biol. 2004; 24: 7-9.
32. Winchester JF, Silberzweig J, Ronco C et al. Sorbents in acute renal failure and end-stage renal disease: middle molecule and cytokine removal. Blood Purif. 2004; 22: 73-77.
33. Wratten ML and Ghezzi PM. Hemodiafiltration with endogenous reinfusion. Contrib Nephrol. 2007; 158: 94-102.
34. Zimmermann J, Herrlinger S, Pruy A, Metzger T and Wanner C. Inflammation enhances cardiovascular risk and mortality in hemodialysis patients. Kidney Int. 1999; 55: 648-658.
35. Zoccali C, Mallamaci F, Tripepi G et al. Adiponectin, metabolic risk factors, and cardiovascular events among patients with end-stage renal disease. J Am Soc Nephrol. 2002; 13: 134-141.
36. Zoccali C, Tripepi G, Cambareri F et al. Adipose tissue cytokines, insulin sensitivity, inflammation, and cardiovascular outcomes in end-stage renal disease patients. J Ren Nutr. 2005; 15: 125-130.