Serum Leptin in Dialysis Renal Osteodystrophy

American Journal of Kidney Diseases

Volumn 42, Issue 5, 2003, Pages 1036-1042

  Coen, Giorgio ^a   Ballanti, Paola ^b   Fischer, Maria Stephanie ^b   Balducci, Alessandro ^b   Calabria, Santo ^b   Colamarco, Luisa ^b   Di Zazzo, Giacomo ^b   Lifrieri, Francesca ^b   Manni, Micaela ^b   Sardella, Daniela ^b   Nofroni, Italo ^b   Bonucci, Ermanno ^b  

^a POLICLINICO UMBERTO I   (Italy)

^b NONE

Author keywords

Bone histomorphometry; Hemodialysis (HD); Leptin; Osteoprotegerin (OPG); Renal osteodystrophy

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; ALUMINUM; CALCIFEDIOL; CALCITRIOL; CALCIUM; LEPTIN; OSTEOCLAST DIFFERENTIATION FACTOR; PARATHYROID HORMONE; PHOSPHATE; TETRACYCLINE; UNCLASSIFIED DRUG;

ADULT; AGED; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; BODY MASS; BONE DISEASE; BONE MASS; BONE TURNOVER; CALCIUM BLOOD LEVEL; CLINICAL ARTICLE; DIALYSIS; FEMALE; HUMAN; HYPERPARATHYROIDISM; MALE; MORPHOMETRICS; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; OSTEOMALACIA; OSTEOPOROSIS; PARATHYROID HORMONE BLOOD LEVEL; PHOSPHATE BLOOD LEVEL; PROTEIN BLOOD LEVEL; RENAL OSTEODYSTROPHY; SEX DIFFERENCE;

EID: 10744220420     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajkd.2003.07.005     Document Type: Article

References (25)

1. Lindsay R, Cosman F, Herrington BS, Himmelstein S: Bone mass and body composition in normal women. J Bone Miner Res 7:55-62, 1992
2. Glauber HS, Vollmer WM, Nevitt MC, Ensrud KE, Orwoll ES: Body weight versus body fat distribution, adiposity, and frame size as predictors of bone density. J Clin Endocrinol Metab 80:1118-1123, 1995
3. Slemenda CW, Hui SH, Longcope C, Wellman H, Johnston CC Jr: Predictors of bone mass in perimenopausal women. Ann Intern Med 112:96-101, 1990
4. Schindler AE, Ebert A, Friedrich E: Conversion of androstenedione to estrone by human tissue. J Clin Endocrinol Metab 35:627-630, 1972
5. Hla MM, Davis JW, Ross PD, et al: A multicenter study of the influence of fat and lean mass on bone mineral content: Evidence for differences in their relative influence at major fracture sites. Early Postmenopausal Intervention Cohort (EPIC) study. Am J Clin Nutr 64:354-360, 1996
6. Revilla M, Villa LF, Hernandez ER, Sanchez-Atrio A, Cortes J, Rico H: Influence of weight and gonadal status on total and regional bone mineral content and on weight bearing and non weight bearing bone, measured by dual-energy x-ray absorptiometry. Maturitas 28:69-74, 1997
7. Considine RV, Sinha MK, Heiman ML, et al: Serum immunoreactive leptin concentrations in normal weight and obese humans. N Engl J Med 334:292-295, 1996
8. Thomas T, Gori F, Khosla S, Jensen MD, Burguera B, Riggs BL: Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes. Endocrinology 140:1630-1638, 1999
9. Burguera B, Hofbauer LC, Thomas T, et al: Leptin reduces ovariectomy-induced bone loss in rats. Endocrinology 142:3546-3553, 2001
10. Ducy P, Amling M, Takeda S, et al: Leptin inhibits bone formation through hypothalamic relay: A central control of bone mass. Cell 100:197-207, 2000
11. Steppan CM, Crawford DT, Chisey-Frink KL, Ke H, Swick AG: Leptin is a potent stimulator of bone growth in ob/ob mice. Regul Pept 92:73-78, 2000
12. Merabet E, Dagogo-Jack S, Coyne DW, et al: Increased plasma leptin concentration in end-stage renal disease. J Clin Endocrinol Metab 82:847-850, 1997
13. Kokot F, Chudek J, Karkoszka H, Adamczak M, Wiecek A, Klimek D: Does PTH influence leptin concentration in haemodialysed uraemic patients? Nephron 82:372-373, 1999
14. Szulc P, Hofbauer LC, Heufelder AE, Roth S, Delmas PD: Osteoprotegerin serum levels in men: Correlation with age, estrogen and testosterone status. J Clin Endocrinol Metab 8:3162-3165, 2001
15. Coen G, Ballanti P, Bonucci E, et al: Bone markers in the diagnosis of low turnover osteodystrophy in haemodialysis patients. Nephrol Dial Transplant 13:2294-2302, 1998
16. Maloney NAQ, Ott SM, Alfrey AC, Miller NL, Coburn JW, Sherrard DJ: Histological quantification of aluminium in iliac bone from patients with renal failure. J Lab Clin Med 99:206-216, 1982
17. Parfitt AM, Drezner MK, Glorieux FH, et al: Bone histomorphometry standardization of nomenclature, symbols and units. Bone Miner 2:595-610, 1987
18. Ballanti P, Bonucci E, Della Rocca C, Milani S, LoCascio V, Imbimbo B: Bone histomorphometric reference values in 88 normal Italian subjects. Bone Miner 11:187-197, 1990
19. Malluche HH, Faugere MC: Renal bone disease 1990: An unmet challenge for the nephrologist. Kidney Int 38:193-211, 1990
20. Fournier A, Ghitu S, Bako G, et al: Bone markers in the diagnosis of low turnover osteodystrophy in haemodialysis patients. Nephrol Dial Transplant 13:2772-2774, 1999 (letter, reply)
21. Coen G, Bonucci E, Ballanti P, et al: PTH1-84 and PTH "7-84" in the noninvasive diagnosis of renal bone disease. Am J Kidney Dis 40:348-354, 2002
22. Goulding A, Taylor RW: Plasma leptin values in relation to bone mass and density and to dynamic biochemical markers of bone resorption and formation in postmenopausal women. Calc Tissue Int 63:456-458, 1998
23. Heimbürger O, Lönnquist F, Danielsson A, Nodenström J, Stenvinkel P: Serum immunoreactive leptin concentration and its relation to body fat content in chronic renal failure. J Am Soc Nephrol 8:847-850, 1997
24. Halloway WR, Collier FM, Aitken CJ, et al: Leptin inhibits osteoclast generation. J Bone Miner Res 17:200-209, 2002
25. Sato M, Takeda N, Sarui H, et al: Association between serum leptin concentrations and mineral density and biochemical markers of bone turnover in adult men. J Clin Endocrinol Metab 86:5273-5276, 2001