-
1
-
-
0033824123
-
Obesity and cardiovascular disease: Pathogenic role of the metabolic syndrome and therapeutic implications
-
Abate N: Obesity and cardiovascular disease: pathogenic role of the metabolic syndrome and therapeutic implications. J Diabetes Complications 14:154-174, 2000
-
(2000)
J Diabetes Complications
, vol.14
, pp. 154-174
-
-
Abate, N.1
-
2
-
-
13344295079
-
Serum immunoreactive-leptin concentrations in normal-weight and obese humans
-
Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL, Caro JF: Serum immunoreactive- leptin concentrations in normal-weight and obese humans. N Engl J Med 334:292-295, 1996
-
(1996)
N Engl J Med
, vol.334
, pp. 292-295
-
-
Considine, R.V.1
Sinha, M.K.2
Heiman, M.L.3
Kriauciunas, A.4
Stephens, T.W.5
Nyce, M.R.6
Ohannesian, J.P.7
Marco, C.C.8
McKee, L.J.9
Bauer, T.L.10
Caro, J.F.11
-
3
-
-
0031735742
-
Leptinemia is not a risk factor for ischemic heart disease in men: Prospective results from the Quebec Cardiovascular Study
-
Couillard C, Lamarche B, Mauriege P, Cantin B, Dagenais GR, Moorjani S, Lupien PJ, Despres JP: Leptinemia is not a risk factor for ischemic heart disease in men: prospective results from the Quebec Cardiovascular Study. Diabetes Care 21:782-786, 1998
-
(1998)
Diabetes Care
, vol.21
, pp. 782-786
-
-
Couillard, C.1
Lamarche, B.2
Mauriege, P.3
Cantin, B.4
Dagenais, G.R.5
Moorjani, S.6
Lupien, P.J.7
Despres, J.P.8
-
4
-
-
10744232583
-
Fasting plasma leptin, tumor necrosis factor-α receptor 2, and monocyte chemoattracting protein 1 concentration in a population of glucose-tolerant and glucose-intolerant women: Impact on cardiovascular mortality
-
Piemonti L, Calori G, Mercalli A, Lattuada G, Monti P, Garancini MP, Costantino F, Ruotolo G, Luzi L, Perseghin G: Fasting plasma leptin, tumor necrosis factor-α receptor 2, and monocyte chemoattracting protein 1 concentration in a population of glucose-tolerant and glucose-intolerant women: impact on cardiovascular mortality. Diabetes Care 26:2883-2889, 2003
-
(2003)
Diabetes Care
, vol.26
, pp. 2883-2889
-
-
Piemonti, L.1
Calori, G.2
Mercalli, A.3
Lattuada, G.4
Monti, P.5
Garancini, M.P.6
Costantino, F.7
Ruotolo, G.8
Luzi, L.9
Perseghin, G.10
-
5
-
-
0035816639
-
Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A
-
Yamagishi SI, Edelstein D, Du XL, Kaneda Y, Guzman M, Brownlee M: Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. J Biol Chem 276:25096-25100, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 25096-25100
-
-
Yamagishi, S.I.1
Edelstein, D.2
Du, X.L.3
Kaneda, Y.4
Guzman, M.5
Brownlee, M.6
-
6
-
-
0035973147
-
Potential role of leptin in angiogenesis: Leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro
-
Park HY, Kwon HM, Lim HJ, Hong BK, Lee JY, Park BE, Jang Y, Cho SY, Kim HS: Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro. Exp Mol Med 33:95-102, 2001
-
(2001)
Exp Mol Med
, vol.33
, pp. 95-102
-
-
Park, H.Y.1
Kwon, H.M.2
Lim, H.J.3
Hong, B.K.4
Lee, J.Y.5
Park, B.E.6
Jang, Y.7
Cho, S.Y.8
Kim, H.S.9
-
7
-
-
0035206659
-
Leptin stimulates rat aortic smooth muscle cell proliferation and migration
-
Oda A, Taniguchi T, Yokoyama M: Leptin stimulates rat aortic smooth muscle cell proliferation and migration. Kobe J Med Sci 47:141-150, 2001
-
(2001)
Kobe J Med Sci
, vol.47
, pp. 141-150
-
-
Oda, A.1
Taniguchi, T.2
Yokoyama, M.3
-
8
-
-
0035844031
-
Leptin enhances the calcification of vascular cells: Artery wall as a target of leptin
-
Parhami F, Tintut Y, Ballard A, Fogelman AM, Demer LL: Leptin enhances the calcification of vascular cells: artery wall as a target of leptin. Circ Res 88:954-960, 2001
-
(2001)
Circ Res
, vol.88
, pp. 954-960
-
-
Parhami, F.1
Tintut, Y.2
Ballard, A.3
Fogelman, A.M.4
Demer, L.L.5
-
9
-
-
0032971218
-
Leptin promotes aggregation of human platelets via the long form of its receptor
-
Nakata M, Yada T, Soejima N, Maruyama I: Leptin promotes aggregation of human platelets via the long form of its receptor. Diabetes 48:426-429, 1999
-
(1999)
Diabetes
, vol.48
, pp. 426-429
-
-
Nakata, M.1
Yada, T.2
Soejima, N.3
Maruyama, I.4
-
10
-
-
0033602850
-
Human leptin stimulates proliferation and activation of human circulating monocytes
-
Santos-Alvarez J, Goberna R, Sanchez-Margalet V: Human leptin stimulates proliferation and activation of human circulating monocytes. Cell Immunol 194:6-11, 1999
-
(1999)
Cell Immunol
, vol.194
, pp. 6-11
-
-
Santos-Alvarez, J.1
Goberna, R.2
Sanchez-Margalet, V.3
-
11
-
-
0035195887
-
Leptin regulation of the immune response and the immunodeficiency of malnutrition
-
Faggioni R, Feingold KR, Grunfeld C: Leptin regulation of the immune response and the immunodeficiency of malnutrition. FASEB J 15:2565-2571, 2001
-
(2001)
FASEB J
, vol.15
, pp. 2565-2571
-
-
Faggioni, R.1
Feingold, K.R.2
Grunfeld, C.3
-
12
-
-
0032572722
-
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
-
Lord GM, Matarese G, Howard JK, Baker RJ, Bloom SR, Lechler RI: Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 394:897-901, 1998
-
(1998)
Nature
, vol.394
, pp. 897-901
-
-
Lord, G.M.1
Matarese, G.2
Howard, J.K.3
Baker, R.J.4
Bloom, S.R.5
Lechler, R.I.6
-
13
-
-
0034136240
-
Expression of leptin receptor (Ob-R) in human atherosclerotic lesions: Potential role in intimal neovascularization
-
Kang SM, Kwon HM, Hong BK, Kim D, Kim LI, Choi EY, Jang Y, Kim HS, Kim MS, Kwon HC: Expression of leptin receptor (Ob-R) in human atherosclerotic lesions: potential role in intimal neovascularization. Yonsei Med J 41:68-75, 2000
-
(2000)
Yonsei Med J
, vol.41
, pp. 68-75
-
-
Kang, S.M.1
Kwon, H.M.2
Hong, B.K.3
Kim, D.4
Kim, L.I.5
Choi, E.Y.6
Jang, Y.7
Kim, H.S.8
Kim, M.S.9
Kwon, H.C.10
-
14
-
-
0017737576
-
Dissociation of obesity, hypercholesterolemia, and diabetes from atherosclerosis in ob/ob mice
-
Yen TT, Allan JA, Pearson DV, Schinitsky MR: Dissociation of obesity, hypercholesterolemia, and diabetes from atherosclerosis in ob/ob mice. Experientia 33:995-996, 1977
-
(1977)
Experientia
, vol.33
, pp. 995-996
-
-
Yen, T.T.1
Allan, J.A.2
Pearson, D.V.3
Schinitsky, M.R.4
-
15
-
-
0035813206
-
Severe hypercholesterolemia, hypertriglyceridemia, and atherosclerosis in mice lacking both leptin and the low density lipoprotein receptor
-
Hasty AH, Shimano H, Osuga J, Namatame I, Takahashi A, Yahagi N, Perrey S, Iizuka Y, Tamura Y, Amemiya-Kudo M, Yoshikawa T, Okazaki H, Ohashi K, Harada K, Matsuzaka T, Sone H, Gotoda T, Nagai R, Ishibashi S, Yamada N: Severe hypercholesterolemia, hypertriglyceridemia, and atherosclerosis in mice lacking both leptin and the low density lipoprotein receptor. J Biol Chem 276:37402-37408, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 37402-37408
-
-
Hasty, A.H.1
Shimano, H.2
Osuga, J.3
Namatame, I.4
Takahashi, A.5
Yahagi, N.6
Perrey, S.7
Iizuka, Y.8
Tamura, Y.9
Amemiya-Kudo, M.10
Yoshikawa, T.11
Okazaki, H.12
Ohashi, K.13
Harada, K.14
Matsuzaka, T.15
Sone, H.16
Gotoda, T.17
Nagai, R.18
Ishibashi, S.19
Yamada, N.20
more..
-
16
-
-
0032511566
-
Effect of intensive blood glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
-
UK Prospective Diabetes Study (UKPDS) Group: Effect of intensive blood glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet 352:854-865, 1998
-
(1998)
Lancet
, vol.352
, pp. 854-865
-
-
-
17
-
-
0032985166
-
A risk-benefit assessment of metformin in type 2 diabetes mellitus
-
Howlett HCS, Bailey CJ: A risk-benefit assessment of metformin in type 2 diabetes mellitus. Drug Sci 20:489-503, 1999
-
(1999)
Drug Sci
, vol.20
, pp. 489-503
-
-
Howlett, H.C.S.1
Bailey, C.J.2
-
18
-
-
0034086934
-
Metformin: Intrinsic vasculoprotective properties
-
Wiensperger NF: Metformin: intrinsic vasculoprotective properties. Diabetes Tech Therap 2:259-272, 2000
-
(2000)
Diabetes Tech Therap
, vol.2
, pp. 259-272
-
-
Wiensperger, N.F.1
-
19
-
-
0042878553
-
Metformin inhibits monocyte adhesion to endothelial cells and foam cell formation
-
Mamputu JC, Wiernsperger N, Renier G: Metformin inhibits monocyte adhesion to endothelial cells and foam cell formation. Br J Diabetes Vasc Dis 3:302-310, 2003
-
(2003)
Br J Diabetes Vasc Dis
, vol.3
, pp. 302-310
-
-
Mamputu, J.C.1
Wiernsperger, N.2
Renier, G.3
-
20
-
-
0036841861
-
NAD(P)H oxidase inhibition improves endothelial function in rat and human blood vessels
-
Hamilton CA, Brosnan MJ, Al-Benna S, Berg G, Dominiczak AF: NAD(P)H oxidase inhibition improves endothelial function in rat and human blood vessels. Hypertension 40:755-762, 2002
-
(2002)
Hypertension
, vol.40
, pp. 755-762
-
-
Hamilton, C.A.1
Brosnan, M.J.2
Al-Benna, S.3
Berg, G.4
Dominiczak, A.F.5
-
21
-
-
0015810429
-
Mechanism of action of the hypoglycemic agent diphenyleneiodonium
-
Holland PC, Clark MG, Bloxham DP, Lardy HA: Mechanism of action of the hypoglycemic agent diphenyleneiodonium. J Biol Chem 248:6050-6056, 1973
-
(1973)
J Biol Chem
, vol.248
, pp. 6050-6056
-
-
Holland, P.C.1
Clark, M.G.2
Bloxham, D.P.3
Lardy, H.A.4
-
22
-
-
0033668399
-
Hypoxia-induced alterations in Ca(2+) mobilization in brain microvascular endothelial cells
-
Kimura C, Oike M, Ito Y: Hypoxia-induced alterations in Ca(2+) mobilization in brain microvascular endothelial cells. Am J Physiol Heart Circ Physiol 279:H2310-H2318, 2000
-
(2000)
Am J Physiol Heart Circ Physiol
, vol.279
-
-
Kimura, C.1
Oike, M.2
Ito, Y.3
-
23
-
-
0025942516
-
The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C
-
Toullec D, Pianetti P, Coste H, Bellevergue P, Grand-Perret T, Ajakane M, Baudet V, Boissin P, Boursier E, Loriolle F, et al: The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J Biol Chem 266:15771-15781, 1991
-
(1991)
J Biol Chem
, vol.266
, pp. 15771-15781
-
-
Toullec, D.1
Pianetti, P.2
Coste, H.3
Bellevergue, P.4
Grand-Perret, T.5
Ajakane, M.6
Baudet, V.7
Boissin, P.8
Boursier, E.9
Loriolle, F.10
-
24
-
-
0029166667
-
A synthetic inhibitor of the mitogen-activated protein kinase cascade
-
Dudley DT, Pang L, Decker SJ, Bridges AJ, Saltiel AR: A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci USA 92:7686-7689, 1995
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7686-7689
-
-
Dudley, D.T.1
Pang, L.2
Decker, S.J.3
Bridges, A.J.4
Saltiel, A.R.5
-
25
-
-
0030772376
-
Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo
-
Pierce JW, Schoenleber R, Jesmok G, Best J, Moore SA, Collins T, Gerritsen ME: Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J Biol Chem 272:21096-21103, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 21096-21103
-
-
Pierce, J.W.1
Schoenleber, R.2
Jesmok, G.3
Best, J.4
Moore, S.A.5
Collins, T.6
Gerritsen, M.E.7
-
26
-
-
0027270211
-
Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2- yl)-2,5-diphenyltetrazolium bromide (MTT): Subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction
-
Berridge MV, Tan AS: Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction. Arch Biochem Biophys 303:474-482, 1993
-
(1993)
Arch Biochem Biophys
, vol.303
, pp. 474-482
-
-
Berridge, M.V.1
Tan, A.S.2
-
27
-
-
0027723123
-
A one-step sandwich enzyme immunoassay for human matrix metalloproteinase 2 (72-kDa gelatinase/type IV collagenase) using monoclonal antibodies
-
Fujimoto N, Mouri N, Iwata K, Ohuchi E, Okada Y, Hayakawa T: A one-step sandwich enzyme immunoassay for human matrix metalloproteinase 2 (72-kDa gelatinase/type IV collagenase) using monoclonal antibodies. Clin Chim Acta 221:91-103, 1993
-
(1993)
Clin Chim Acta
, vol.221
, pp. 91-103
-
-
Fujimoto, N.1
Mouri, N.2
Iwata, K.3
Ohuchi, E.4
Okada, Y.5
Hayakawa, T.6
-
28
-
-
0025804191
-
A monoclonal antibody to the phosphorylated form of glial fibrillary acidic protein: Application to a non-radioactive method for measuring protein kinase activities
-
Yano T, Taura C, Shibata M, Hirono Y, Ando S, Kusubata M, Takahashi T, Inagaki M: A monoclonal antibody to the phosphorylated form of glial fibrillary acidic protein: application to a non-radioactive method for measuring protein kinase activities. Biochem. Biophys Res Commun 175:1144-1151, 1991
-
(1991)
Biochem Biophys Res Commun
, vol.175
, pp. 1144-1151
-
-
Yano, T.1
Taura, C.2
Shibata, M.3
Hirono, Y.4
Ando, S.5
Kusubata, M.6
Takahashi, T.7
Inagaki, M.8
-
29
-
-
0034664960
-
A new phosphospecific cell-based ELISA for p42/p44 mitogen-activated protein kinase (MAPK), p38 MAPK, protein kinase B and cAMP-response-element- binding protein
-
Versteeg HH, Nyhuis E, van den Brink GR, Evertzen M, Pynaert GN, van Deventer SJ, Coffer PJ, Peppelenbosch MP: A new phosphospecific cell-based ELISA for p42/p44 mitogen-activated protein kinase (MAPK), p38 MAPK, protein kinase B and cAMP-response-element-binding protein. Biochem J 350:717-722, 2000
-
(2000)
Biochem J
, vol.350
, pp. 717-722
-
-
Versteeg, H.H.1
Nyhuis, E.2
Van Den Brink, G.R.3
Evertzen, M.4
Pynaert, G.N.5
Van Deventer, S.J.6
Coffer, P.J.7
Peppelenbosch, M.P.8
-
30
-
-
0035866185
-
Development of a sensitive multi-well colorimetric assay for active NFkappaB
-
Renard P, Ernest I, Houbion A, Art M, Le Calvez H, Raes M, Remade J: Development of a sensitive multi-well colorimetric assay for active NFkappaB. Nucleic Acid Res 29:E21-E25, 2001
-
(2001)
Nucleic Acid Res
, vol.29
-
-
Renard, P.1
Ernest, I.2
Houbion, A.3
Art, M.4
Le Calvez, H.5
Raes, M.6
Remade, J.7
-
31
-
-
18144447850
-
Antiatherogenic properties of metformin: The experimental evidence
-
Mamputu JC, Wiernsperger NF, Renier G: Antiatherogenic properties of metformin: the experimental evidence. Diabetes Metab 29:71-76, 2003
-
(2003)
Diabetes Metab
, vol.29
, pp. 71-76
-
-
Mamputu, J.C.1
Wiernsperger, N.F.2
Renier, G.3
-
32
-
-
0020639876
-
Metformin action on lipid metabolism in lesions of experimental aortic atherosclerosis of rabbits
-
Marquié G: Metformin action on lipid metabolism in lesions of experimental aortic atherosclerosis of rabbits. Atherosclerosis 47:7-17, 1983
-
(1983)
Atherosclerosis
, vol.47
, pp. 7-17
-
-
Marquié, G.1
-
33
-
-
0018739904
-
Comparative effects of metformin and phenformin on the progression and regression of cholesterol induced atherosclerosis in rabbits
-
Marquié G: Comparative effects of metformin and phenformin on the progression and regression of cholesterol induced atherosclerosis in rabbits. Paroi Arterielle 5:209-218, 1973
-
(1973)
Paroi Arterielle
, vol.5
, pp. 209-218
-
-
Marquié, G.1
-
34
-
-
0343730957
-
Metformin inhibits the growth of human vascular cells: A new potentially antiatherogenic drug effect
-
Bunting CE, Koschinsky T, Rütter R, Gries FA: Metformin inhibits the growth of human vascular cells: a new potentially antiatherogenic drug effect (Abstract). Diabetologia 29:523A, 1986
-
(1986)
Diabetologia
, vol.29
-
-
Bunting, C.E.1
Koschinsky, T.2
Rütter, R.3
Gries, F.A.4
-
35
-
-
21344450854
-
Experimental studies on the antiatherosclerotic effect of metformin
-
Carlson LA, Paoletti R, Sirtori CR, Weber G, Eds. New York, Raven Press
-
Weber G, Catapano A, Ghiselli G, Sirtori CR: Experimental studies on the antiatherosclerotic effect of metformin. In Proceedings of the International Conference on Atherosclerosis. Carlson LA, Paoletti R, Sirtori CR, Weber G, Eds. New York, Raven Press, 1978, p. 318-325
-
(1978)
Proceedings of the International Conference on Atherosclerosis
, pp. 318-325
-
-
Weber, G.1
Catapano, A.2
Ghiselli, G.3
Sirtori, C.R.4
-
36
-
-
0347823193
-
Leptin promotes vascular remodeling and neointimal growth in mice
-
Schäfer K, Halle M, Goeschen C, Dellas C, Pynn M, Loskutoff DJ, Konstantinides S: Leptin promotes vascular remodeling and neointimal growth in mice. Arterioscler Thomb Vasc Biol 24:112-117, 2004
-
(2004)
Arterioscler Thomb Vasc Biol
, vol.24
, pp. 112-117
-
-
Schäfer, K.1
Halle, M.2
Goeschen, C.3
Dellas, C.4
Pynn, M.5
Loskutoff, D.J.6
Konstantinides, S.7
-
37
-
-
4043077647
-
Plasma leptin levels are associated with coronary atherosclerosis in type 2 diabetes
-
Reilly MP, Iqbal N, Schutta M, Wolfe ML, Scally M, Localio AR, Rader DJ, Kimmel SE: Plasma leptin levels are associated with coronary atherosclerosis in type 2 diabetes. J Clin Endocrinol Metab 89:3872-3878, 2004
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 3872-3878
-
-
Reilly, M.P.1
Iqbal, N.2
Schutta, M.3
Wolfe, M.L.4
Scally, M.5
Localio, A.R.6
Rader, D.J.7
Kimmel, S.E.8
-
38
-
-
0042696057
-
Leptin decreases plasma paraoxonase 1 (PON 1) activity and induces oxidative stress: The possible novel mechanism for proatherogenic effect of chronic hyperleptinemia
-
Beltowski J, Wojccicka G, Jamroz A: Leptin decreases plasma paraoxonase 1 (PON 1) activity and induces oxidative stress: the possible novel mechanism for proatherogenic effect of chronic hyperleptinemia. Atherosclerosis 170:21-29, 2003
-
(2003)
Atherosclerosis
, vol.170
, pp. 21-29
-
-
Beltowski, J.1
Wojccicka, G.2
Jamroz, A.3
-
39
-
-
0032999682
-
Leptin induces oxidative stress in human endothelial cells
-
Bouloumie A, Marumo T, Lafontan M, Busse R: Leptin induces oxidative stress in human endothelial cells. FASEB J 13:1231-1238, 1999
-
(1999)
FASEB J
, vol.13
, pp. 1231-1238
-
-
Bouloumie, A.1
Marumo, T.2
Lafontan, M.3
Busse, R.4
-
40
-
-
0043268732
-
Leptin increases lipoprotein lipase secretion by macrophages: Involvement of oxidative stress and protein kinase C
-
Maingrette F, Renier G: Leptin increases lipoprotein lipase secretion by macrophages: involvement of oxidative stress and protein kinase C. Diabetes 52:2121-2128, 2003
-
(2003)
Diabetes
, vol.52
, pp. 2121-2128
-
-
Maingrette, F.1
Renier, G.2
-
41
-
-
0037414393
-
NAD(P)H oxidase participates in the signaling events in high-glucose-induced proliferation of vascular smooth muscle cells
-
Lee HS, Son SM, Kim YK, Hong KW, Kim CD: NAD(P)H oxidase participates in the signaling events in high-glucose-induced proliferation of vascular smooth muscle cells. Life Sci 72:2719-2730, 2003
-
(2003)
Life Sci
, vol.72
, pp. 2719-2730
-
-
Lee, H.S.1
Son, S.M.2
Kim, Y.K.3
Hong, K.W.4
Kim, C.D.5
-
42
-
-
0036963969
-
Redox signaling through NADPH oxidases: Involvement in vascular proliferation and coagulation
-
Gorlach A, Kietzmann T, Hess J: Redox signaling through NADPH oxidases: involvement in vascular proliferation and coagulation. Ann N Y Acad Sci 973:505-507, 2002
-
(2002)
Ann N Y Acad Sci
, vol.973
, pp. 505-507
-
-
Gorlach, A.1
Kietzmann, T.2
Hess, J.3
-
43
-
-
0034527379
-
Effect of four-week metformin treatment on plasma and erythrocyte antioxidative defense enzymes in newly diagnosed obese patients with type 2 diabetes
-
Pavlovic D, Kocic R, Kocic G, Jevtovic T, Radenkovic S, Mikic D, Stojanovic M, Djordjevic PB: Effect of four-week metformin treatment on plasma and erythrocyte antioxidative defense enzymes in newly diagnosed obese patients with type 2 diabetes. Diabetes Obes Metab 2:251-256, 2000
-
(2000)
Diabetes Obes Metab
, vol.2
, pp. 251-256
-
-
Pavlovic, D.1
Kocic, R.2
Kocic, G.3
Jevtovic, T.4
Radenkovic, S.5
Mikic, D.6
Stojanovic, M.7
Djordjevic, P.B.8
-
44
-
-
0038410183
-
An intracellular modulation of free radical production could contribute to the beneficial effects of metformin towards oxidative stress
-
Bonnefont-Rousselot D, Raji B, Walrand S, Gardes-Albert M, Jore D, Legrand A, Peynet J, Vasson MP: An intracellular modulation of free radical production could contribute to the beneficial effects of metformin towards oxidative stress. Metabolism 52:586-589, 2003
-
(2003)
Metabolism
, vol.52
, pp. 586-589
-
-
Bonnefont-Rousselot, D.1
Raji, B.2
Walrand, S.3
Gardes-Albert, M.4
Jore, D.5
Legrand, A.6
Peynet, J.7
Vasson, M.P.8
-
45
-
-
0036255463
-
Metformin decreases platelet superoxide anion production in diabetic patients
-
Gargiulo P, Caccese D, Pignatelli P, Brufani C, De Vito F, Marino R, Lauro R, Violi F, Di Mario U, Sanguigni V: Metformin decreases platelet superoxide anion production in diabetic patients. Diabetes Metab Res Rev 18:156-159, 2002
-
(2002)
Diabetes Metab Res Rev
, vol.18
, pp. 156-159
-
-
Gargiulo, P.1
Caccese, D.2
Pignatelli, P.3
Brufani, C.4
De Vito, F.5
Marino, R.6
Lauro, R.7
Violi, F.8
Di Mario, U.9
Sanguigni, V.10
-
46
-
-
0033765672
-
High glucose level and free fatty acids stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells
-
Inoguchi T, Li P, Umeda F, Yu HY, Kakimoto M, Imamura M, Aoki T, Etoh T, Hashimoto T, Naruse M, Sano H, Utsumi H, Nawata H: High glucose level and free fatty acids stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells. Diabetes 49:1939-1945, 2000
-
(2000)
Diabetes
, vol.49
, pp. 1939-1945
-
-
Inoguchi, T.1
Li, P.2
Umeda, F.3
Yu, H.Y.4
Kakimoto, M.5
Imamura, M.6
Aoki, T.7
Etoh, T.8
Hashimoto, T.9
Naruse, M.10
Sano, H.11
Utsumi, H.12
Nawata, H.13
-
47
-
-
0032407020
-
Reactive oxygen species are critical in the oleic-acid-mediated mitogenic signaling pathway in vascular smooth muscle cells
-
Lu G, Greene EL, Nagai T, Egan BM: Reactive oxygen species are critical in the oleic-acid-mediated mitogenic signaling pathway in vascular smooth muscle cells. Hypertension 32:1003-1010, 1998
-
(1998)
Hypertension
, vol.32
, pp. 1003-1010
-
-
Lu, G.1
Greene, E.L.2
Nagai, T.3
Egan, B.M.4
-
48
-
-
0034804569
-
Glycated serum albumin-induced vascular smooth muscle cell proliferation through activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by protein kinase C
-
Hattori Y, Kakishita H, Akimoto K, Matsumura M, Kasai K: Glycated serum albumin-induced vascular smooth muscle cell proliferation through activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by protein kinase C. Biochem Biophys Res Commun 281:891-896, 2001
-
(2001)
Biochem Biophys Res Commun
, vol.281
, pp. 891-896
-
-
Hattori, Y.1
Kakishita, H.2
Akimoto, K.3
Matsumura, M.4
Kasai, K.5
-
49
-
-
0032538875
-
Leptin, the product of Ob gene, promotes angiogenesis
-
Bouloumie A, Drexler HCA, Lafontan M, Busse R: Leptin, the product of Ob gene, promotes angiogenesis. Circ Res 83:1059-1066, 1998
-
(1998)
Circ Res
, vol.83
, pp. 1059-1066
-
-
Bouloumie, A.1
Drexler, H.C.A.2
Lafontan, M.3
Busse, R.4
-
50
-
-
0036840309
-
Leptin induces endothelial cell migration through Akt which is inhibited by PPARγ ligands
-
Goetze S, Bungenstock A, Czupalla C, Eilers F, Stawowy P, Kintscher U, Spencer-Hänsch C, Graf K, Nürnberg B, Law RE, Fleck E, Gräfe M: Leptin induces endothelial cell migration through Akt which is inhibited by PPARγ ligands. Hypertension 40:748-754, 2002
-
(2002)
Hypertension
, vol.40
, pp. 748-754
-
-
Goetze, S.1
Bungenstock, A.2
Czupalla, C.3
Eilers, F.4
Stawowy, P.5
Kintscher, U.6
Spencer-Hänsch, C.7
Graf, K.8
Nürnberg, B.9
Law, R.E.10
Fleck, E.11
Gräfe, M.12
-
51
-
-
0029417282
-
d-alpha tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties
-
Tasinato A, Boscoboinik D, Bartoli GM, Maroni P, Azzi A: d-alpha tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties. Proc Natl Acad Sci U S A 92:12190-12194, 1995
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 12190-12194
-
-
Tasinato, A.1
Boscoboinik, D.2
Bartoli, G.M.3
Maroni, P.4
Azzi, A.5
-
52
-
-
0030834577
-
Alpha-tocopherol as a modulator of smooth muscle cell proliferation
-
Azzi A, Boscoboinik D, Clement S, Marilley D, Ozer NK, Ricciarelli R, Tasinato A: Alpha-tocopherol as a modulator of smooth muscle cell proliferation. Prostaglandins Leukot Essent Fatty Acids 57:507-514, 1997
-
(1997)
Prostaglandins Leukot Essent Fatty Acids
, vol.57
, pp. 507-514
-
-
Azzi, A.1
Boscoboinik, D.2
Clement, S.3
Marilley, D.4
Ozer, N.K.5
Ricciarelli, R.6
Tasinato, A.7
-
53
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, Wu M, Ventre J, Doebber T, Fujii N, Musi N, Hirshman MF, Goodyear LJ, Moller DE: Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 108:1167-1174, 2001
-
(2001)
J Clin Invest
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
Wu, M.7
Ventre, J.8
Doebber, T.9
Fujii, N.10
Musi, N.11
Hirshman, M.F.12
Goodyear, L.J.13
Moller, D.E.14
-
54
-
-
0036095269
-
Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: Inhibition by the AMP-activated protein kinase activation
-
Ido Y, Carling D, Ruderman N: Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation. Diabetes 51:159-167, 2002
-
(2002)
Diabetes
, vol.51
, pp. 159-167
-
-
Ido, Y.1
Carling, D.2
Ruderman, N.3
-
55
-
-
0033559856
-
AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: Evidence that sn-glycerol-3-phosphate acyltransferase is a novel target
-
Muoio DM, Seefeld K, Witters LA, Coleman RA: AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target. Biochem J 338:783-791, 1999
-
(1999)
Biochem J
, vol.338
, pp. 783-791
-
-
Muoio, D.M.1
Seefeld, K.2
Witters, L.A.3
Coleman, R.A.4
-
56
-
-
0033037930
-
Hyperglycemia-induced activation of transcription factor κB in vascular smooth muscle cells
-
Yerneni KK, Bai W, Khan BV, Medford RM, Natarajan R: Hyperglycemia- induced activation of transcription factor κB in vascular smooth muscle cells. Diabetes 48:855-864, 1999
-
(1999)
Diabetes
, vol.48
, pp. 855-864
-
-
Yerneni, K.K.1
Bai, W.2
Khan, B.V.3
Medford, R.M.4
Natarajan, R.5
-
57
-
-
0033966202
-
Regulation of vascular smooth muscle cell proliferation by nuclear factor-κ and its inhibitor, I-κB
-
Hoshi S, Goto M, Koyama N, Nomoto K, Tanaka H: Regulation of vascular smooth muscle cell proliferation by nuclear factor-κ and its inhibitor, I-κB. J Biol Chem 275:883-889, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 883-889
-
-
Hoshi, S.1
Goto, M.2
Koyama, N.3
Nomoto, K.4
Tanaka, H.5
-
58
-
-
14344257169
-
AMPK inhibits fatty acid-induced increases in NF-κB transactivation in cultured human umbilical vein endothelial cells
-
Cacicedo JM, Yagihashi N, Keaney JF, Ruderman NB, Ido Y: AMPK inhibits fatty acid-induced increases in NF-κB transactivation in cultured human umbilical vein endothelial cells. Biochem Biophys Res Comm 324:1204-1209, 2004
-
(2004)
Biochem Biophys Res Comm
, vol.324
, pp. 1204-1209
-
-
Cacicedo, J.M.1
Yagihashi, N.2
Keaney, J.F.3
Ruderman, N.B.4
Ido, Y.5
-
59
-
-
0028030129
-
Extracellular matrix degrading metalloproteinases in the pathogenesis of arteriosclerosis
-
Newby AC, Southgate KM, Davies M: Extracellular matrix degrading metalloproteinases in the pathogenesis of arteriosclerosis. Basic Res Cardiol 89:59-70, 1994
-
(1994)
Basic Res Cardiol
, vol.89
, pp. 59-70
-
-
Newby, A.C.1
Southgate, K.M.2
Davies, M.3
-
60
-
-
19944434168
-
Angiotensin II induces MMP-2 in a p47phox-dependent manner. Biochem
-
Luchtefeld M, Grote K, Grothusen C, Bley S, Bandlow N, Selle T, Struber M, Haverich A, Bavendiek U, Drexler H, Schieffer B: Angiotensin II induces MMP-2 in a p47phox-dependent manner. Biochem. Biophys Res Commun 328:183-188, 2005
-
(2005)
Biophys Res Commun
, vol.328
, pp. 183-188
-
-
Luchtefeld, M.1
Grote, K.2
Grothusen, C.3
Bley, S.4
Bandlow, N.5
Selle, T.6
Struber, M.7
Haverich, A.8
Bavendiek, U.9
Drexler, H.10
Schieffer, B.11
-
61
-
-
0037178897
-
Activation of protein kinase C zeta is essential for cytokine-induced metalloproteinase-1, -3, and -9 secretion from rabbit smooth muscle cells and inhibits proliferation
-
Hussain S, Assender JW, Bond M, Wong L-F, Murphy D, Newby AC: Activation of protein kinase C zeta is essential for cytokine-induced metalloproteinase-1, -3, and -9 secretion from rabbit smooth muscle cells and inhibits proliferation. J Biol Chem 277:27345-27352, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 27345-27352
-
-
Hussain, S.1
Assender, J.W.2
Bond, M.3
Wong, L.-F.4
Murphy, D.5
Newby, A.C.6
-
62
-
-
0032508674
-
Synergistic upregulation of metalloproteinase-9 by growth factors and inflammatory cytokines: An absolute requirement for transcription factor NF-kappa B
-
Bond M, Fabunmi RP, Baker AH, Newby AC: Synergistic upregulation of metalloproteinase-9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF-kappa B. FEBS Lett 435:29-34, 1998
-
(1998)
FEBS Lett
, vol.435
, pp. 29-34
-
-
Bond, M.1
Fabunmi, R.P.2
Baker, A.H.3
Newby, A.C.4
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