-
1
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-432, 1994
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
2
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
Tartaglia LA, Dembski M, Weng X, Deng N, Culpepper J, Devos R, Richards GJ, Campfield LA, Clark FT, Deeds J, Muir C, Sanker S, Moriarty A, Moore KJ, Smutko JS, Mays GG, Woolf EA, Monroe CA, Tepper RI: Identification and expression cloning of a leptin receptor, OB-R, Cell 83:1263-1271, 1995
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
Dembski, M.2
Weng, X.3
Deng, N.4
Culpepper, J.5
Devos, R.6
Richards, G.J.7
Campfield, L.A.8
Clark, F.T.9
Deeds, J.10
Muir, C.11
Sanker, S.12
Moriarty, A.13
Moore, K.J.14
Smutko, J.S.15
Mays, G.G.16
Woolf, E.A.17
Monroe, C.A.18
Tepper, R.I.19
-
3
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, Ellis SJ, Lakey ND, Culpepper J, Moore KJ, Breitbart RE, Duyk GM, Tepper RI, Morgenstern JP: Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 84:491-495, 1996
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
Lakey, N.D.7
Culpepper, J.8
Moore, K.J.9
Breitbart, R.E.10
Duyk, G.M.11
Tepper, R.I.12
Morgenstern, J.P.13
-
4
-
-
0029939065
-
Decreased food intake does not completely account for adiposity reduction after ob protein infusion
-
Levin N, Nelson C, Gurney A, Vandlen R, de-Sauvage F: Decreased food intake does not completely account for adiposity reduction after ob protein infusion. Proc Natl Acad Sci U S A 93:1726-1730, 1996
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 1726-1730
-
-
Levin, N.1
Nelson, C.2
Gurney, A.3
Vandlen, R.4
De-Sauvage, F.5
-
5
-
-
0030010388
-
Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
-
Chehab FF, Lim ME, Lu R: Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nat Genet 12:318-320, 1996
-
(1996)
Nat Genet
, vol.12
, pp. 318-320
-
-
Chehab, F.F.1
Lim, M.E.2
Lu, R.3
-
6
-
-
0029896530
-
Role of leptin in the neuroendocrine response to fasting
-
Ahima RS, Prabakaran D, Mantzoros C, Qu D, Lowell B, Maratos-Flier E, Flier JS: Role of leptin in the neuroendocrine response to fasting. Nature 382:250-252, 1996
-
(1996)
Nature
, vol.382
, pp. 250-252
-
-
Ahima, R.S.1
Prabakaran, D.2
Mantzoros, C.3
Qu, D.4
Lowell, B.5
Maratos-Flier, E.6
Flier, J.S.7
-
7
-
-
0024160877
-
Banting Lecture 1988: Role of insulin resistance in human disease
-
Reaven GM: Banting Lecture 1988: role of insulin resistance in human disease. Diabetes 37:1595-1607, 1988
-
(1988)
Diabetes
, vol.37
, pp. 1595-1607
-
-
Reaven, G.M.1
-
8
-
-
0029050937
-
Overexpression of the obese (ob) gene in adipose tissue of human obese subjects
-
Lonnqvist F, Amer P, Nordfors L, Schalling M: Overexpression of the obese (ob) gene in adipose tissue of human obese subjects, Nat Med 1:950-953, 1995
-
(1995)
Nat Med
, vol.1
, pp. 950-953
-
-
Lonnqvist, F.1
Amer, P.2
Nordfors, L.3
Schalling, M.4
-
9
-
-
0029083859
-
Increased obese mRNA expression in omental fat cells from massively obese humans
-
Hamilton BS, Paglia D, Kwan AY, Deitel M: Increased obese mRNA expression in omental fat cells from massively obese humans. Nat Med 1:953-956, 1995
-
(1995)
Nat Med
, vol.1
, pp. 953-956
-
-
Hamilton, B.S.1
Paglia, D.2
Kwan, A.Y.3
Deitel, M.4
-
10
-
-
0030942844
-
The leptin receptor
-
Tartaglia LA: The leptin receptor. J Biol Chem 272:6093-6096, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 6093-6096
-
-
Tartaglia, L.A.1
-
11
-
-
0029952911
-
Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells
-
Gainsford T, Willson TA, Metcalf D, Handman E, McFarlane C, Ng A, Nicola NA, Alexander WS, Hilton DJ: Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells. Proc Natl Acad Sci U S A 93:14564-14568, 1996
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 14564-14568
-
-
Gainsford, T.1
Willson, T.A.2
Metcalf, D.3
Handman, E.4
McFarlane, C.5
Ng, A.6
Nicola, N.A.7
Alexander, W.S.8
Hilton, D.J.9
-
12
-
-
0030007116
-
Novel B219/OB receptor isoforms: Possible role of leptin in hematopoiesis and reproduction
-
Cioffi JA, Shafer AW, Zupancic TJ, Smith-Gbur J, Mikhail A, Platika D, Snodgrass HR: Novel B219/OB receptor isoforms: possible role of leptin in hematopoiesis and reproduction. Nat Med 2:585-589, 1996
-
(1996)
Nat Med
, vol.2
, pp. 585-589
-
-
Cioffi, J.A.1
Shafer, A.W.2
Zupancic, T.J.3
Smith-Gbur, J.4
Mikhail, A.5
Platika, D.6
Snodgrass, H.R.7
-
13
-
-
0031010408
-
Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues
-
Fei H, Okano HJ, Li C, Lee GH, Zhao C, Darnell R, Friedman JM: Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. Proc Natl Acad Sci U S A 94:7001-7005, 1997
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 7001-7005
-
-
Fei, H.1
Okano, H.J.2
Li, C.3
Lee, G.H.4
Zhao, C.5
Darnell, R.6
Friedman, J.M.7
-
14
-
-
0031887488
-
Immunohistochemical localization of leptin receptor in the rat brain
-
Shioda S, Hunahashi H, Nakajo S, Nakaya K, Yada T, Maruta O, Nakai Y: Immunohistochemical localization of leptin receptor in the rat brain. Neurosci Lett 243:41-44, 1998
-
(1998)
Neurosci Lett
, vol.243
, pp. 41-44
-
-
Shioda, S.1
Hunahashi, H.2
Nakajo, S.3
Nakaya, K.4
Yada, T.5
Maruta, O.6
Nakai, Y.7
-
15
-
-
0030886339
-
Direct stimulation of basal insulin secretion by physiological concentrations of leptin in pancreatic β cells
-
Tanizawa Y, Okuya S, Ishihara H, Asano T, Yada T, Oka Y: Direct stimulation of basal insulin secretion by physiological concentrations of leptin in pancreatic β cells. Endocrinology 138:4513-4516, 1997
-
(1997)
Endocrinology
, vol.138
, pp. 4513-4516
-
-
Tanizawa, Y.1
Okuya, S.2
Ishihara, H.3
Asano, T.4
Yada, T.5
Oka, Y.6
-
16
-
-
0031577546
-
Detection and quantification of the leptin receptor splice variants Ob-Ra, b, and, e in different mouse tissues
-
Lollmann B, Gruninger S, Stricker-Krongrad A, Chiesi M: Detection and quantification of the leptin receptor splice variants Ob-Ra, b, and, e in different mouse tissues. Biochem Biophys Res Commun 238:648-652, 1997
-
(1997)
Biochem Biophys Res Commun
, vol.238
, pp. 648-652
-
-
Lollmann, B.1
Gruninger, S.2
Stricker-Krongrad, A.3
Chiesi, M.4
-
17
-
-
0029889997
-
Gp130, a shared signal transducing receptor component for hematopoietic and neuropoietic cytokines
-
Taga T: Gp130, a shared signal transducing receptor component for hematopoietic and neuropoietic cytokines. J Neurochem 67:1-10, 1996
-
(1996)
J Neurochem
, vol.67
, pp. 1-10
-
-
Taga, T.1
-
18
-
-
0025162844
-
Structural design and molecular evolution of a cytokine receptor superfamily
-
Bazan JF: Structural design and molecular evolution of a cytokine receptor superfamily. Proc Natl Acad Sci U S A 87:6934-6938, 1990
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 6934-6938
-
-
Bazan, J.F.1
-
19
-
-
0028117163
-
Cytokine signal transduction
-
Kishimoto T, Taga T, Akira S: Cytokine signal transduction. Cell 76:253-262, 1994
-
(1994)
Cell
, vol.76
, pp. 253-262
-
-
Kishimoto, T.1
Taga, T.2
Akira, S.3
-
20
-
-
0028302409
-
Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand
-
de-Sauvage FJ, Hass PE, Spencer SD, Malloy BE, Gurney AL, Spencer SA, Darbonne WC, Henzel WJ, Wong SC, Kuang WJ, Oles KJ, Hultgren B, Solberg LA Jr, Goeddel DV, Eaton DL: Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature 369:533-538, 1994
-
(1994)
Nature
, vol.369
, pp. 533-538
-
-
De-Sauvage, F.J.1
Hass, P.E.2
Spencer, S.D.3
Malloy, B.E.4
Gurney, A.L.5
Spencer, S.A.6
Darbonne, W.C.7
Henzel, W.J.8
Wong, S.C.9
Kuang, W.J.10
Oles, K.J.11
Hultgren, B.12
Solberg L.A., Jr.13
Goeddel, D.V.14
Eaton, D.L.15
-
21
-
-
0028343099
-
Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl
-
Bartley TD, Bogenberger J, Hunt P, Li YS, Lu HS, Martin F, Chang MS, Samal B, Nichol JL, Swift S, Johnson MJ, Hsu RY, Parker VT, Suggs S, Skrine JD, Merewether LA, Clogston C, Hsu E, Hokom MM, Hornkohl A, Choi E, Pangelinan M, Sun Y, Mar V, McNinch J, Simonet L, Jacobsen F, Xie C, Shutter J, Chute H, Basu R, Selander L, Trollinger D, Sieu L, Padilla D, Trail G, Elliott G, Izumi R, Covey T, Crouse J, Garcia A, Xu W, Castillo JD, Biron J, Cole S, Hu MCT, Pacifici R, Ponting I, Saris C, Wen D, Yung YP, Lin H, Bosselmam RA: Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl. Cell 77:1117-1124, 1994
-
(1994)
Cell
, vol.77
, pp. 1117-1124
-
-
Bartley, T.D.1
Bogenberger, J.2
Hunt, P.3
Li, Y.S.4
Lu, H.S.5
Martin, F.6
Chang, M.S.7
Samal, B.8
Nichol, J.L.9
Swift, S.10
Johnson, M.J.11
Hsu, R.Y.12
Parker, V.T.13
Suggs, S.14
Skrine, J.D.15
Merewether, L.A.16
Clogston, C.17
Hsu, E.18
Hokom, M.M.19
Hornkohl, A.20
Choi, E.21
Pangelinan, M.22
Sun, Y.23
Mar, V.24
McNinch, J.25
Simonet, L.26
Jacobsen, F.27
Xie, C.28
Shutter, J.29
Chute, H.30
Basu, R.31
Selander, L.32
Trollinger, D.33
Sieu, L.34
Padilla, D.35
Trail, G.36
Elliott, G.37
Izumi, R.38
Covey, T.39
Crouse, J.40
Garcia, A.41
Xu, W.42
Castillo, J.D.43
Biron, J.44
Cole, S.45
Hu, M.C.T.46
Pacifici, R.47
Ponting, I.48
Saris, C.49
Wen, D.50
Yung, Y.P.51
Lin, H.52
Bosselmam, R.A.53
more..
-
22
-
-
9344225757
-
Thrombopoietin primes human platelet aggregation induced by shear stress and by multiple agonists
-
Oda A, Miyakawa Y, Druker BJ, Ozaki K, Yabusaki K, Shirasawa Y, Handa M, Kato T, Miyazaki H, Shimosaka A, Ikeda Y: Thrombopoietin primes human platelet aggregation induced by shear stress and by multiple agonists. Blood 87:4664-4670, 1996
-
(1996)
Blood
, vol.87
, pp. 4664-4670
-
-
Oda, A.1
Miyakawa, Y.2
Druker, B.J.3
Ozaki, K.4
Yabusaki, K.5
Shirasawa, Y.6
Handa, M.7
Kato, T.8
Miyazaki, H.9
Shimosaka, A.10
Ikeda, Y.11
-
23
-
-
0028845877
-
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
-
Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S, Kern PA, Friedman JM: Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1:1155-1161, 1995
-
(1995)
Nat Med
, vol.1
, pp. 1155-1161
-
-
Maffei, M.1
Halaas, J.2
Ravussin, E.3
Pratley, R.E.4
Lee, G.H.5
Zhang, Y.6
Fei, H.7
Kim, S.8
Lallone, R.9
Ranganathan, S.10
Kern, P.A.11
Friedman, J.M.12
-
24
-
-
0030594830
-
Decreased cerebrospinal-fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance
-
Caro JF, Kolaczynski JW, Nyce MR, Ohannesian JP, Opentanova I, Goldman WH, Lynn RB, Zhang PL, Sinha MK, Considine RV: Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance. Lancet 348:159-161, 1996
-
(1996)
Lancet
, vol.348
, pp. 159-161
-
-
Caro, J.F.1
Kolaczynski, J.W.2
Nyce, M.R.3
Ohannesian, J.P.4
Opentanova, I.5
Goldman, W.H.6
Lynn, R.B.7
Zhang, P.L.8
Sinha, M.K.9
Considine, R.V.10
-
25
-
-
0029881125
-
Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
-
Schwartz MW, Peskind E, Raskind M, Boyko EJ, Porte D Jr Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans. Nat Med 2:589-593, 1996
-
(1996)
Nat Med
, vol.2
, pp. 589-593
-
-
Schwartz, M.W.1
Peskind, E.2
Raskind, M.3
Boyko, E.J.4
Porte D., Jr.5
-
26
-
-
0024391834
-
The deadly quartet: Upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension
-
Kaplan NM: The deadly quartet: upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension. Arch Intern Med 149:1514-1520, 1989
-
(1989)
Arch Intern Med
, vol.149
, pp. 1514-1520
-
-
Kaplan, N.M.1
-
27
-
-
0026021161
-
Insulin resistance: A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
-
DeFronzo RA, Ferrannini E: Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 14:173-194, 1991
-
(1991)
Diabetes Care
, vol.14
, pp. 173-194
-
-
DeFronzo, R.A.1
Ferrannini, E.2
|