-
1
-
-
0016723594
-
An endotoxin-induced serum factor that causes necrosis of tumors
-
Carswell, E. A., Old, L. J., Kassel, R. L., Green, S., Fiore, N. and Williamson, B., An endotoxin-induced serum factor that causes necrosis of tumors. Proc. Natl. Acad. Sci. USA 1975. 72: 3666-3670.
-
(1975)
Proc. Natl. Acad. Sci. USA
, vol.72
, pp. 3666-3670
-
-
Carswell, E.A.1
Old, L.J.2
Kassel, R.L.3
Green, S.4
Fiore, N.5
Williamson, B.6
-
2
-
-
0022371461
-
Identity of tumour necrosis factor and the macrophage-secreted factor cachectin
-
Beutler, B., Greenwald, D., Hulmes, J. D., Chang, M., Pan, Y. C., Mathison, J., Ulevitch, R. and Cerami, A., Identity of tumour necrosis factor and the macrophage-secreted factor cachectin. Nature 1985. 316: 552-554.
-
(1985)
Nature
, vol.316
, pp. 552-554
-
-
Beutler, B.1
Greenwald, D.2
Hulmes, J.D.3
Chang, M.4
Pan, Y.C.5
Mathison, J.6
Ulevitch, R.7
Cerami, A.8
-
3
-
-
0026717674
-
The pathophysiology of rumor necrosis factors
-
Vassalli, P., The pathophysiology of rumor necrosis factors. Annu. Rev. Immunol. 1992. 10: 411-452.
-
(1992)
Annu. Rev. Immunol.
, vol.10
, pp. 411-452
-
-
Vassalli, P.1
-
4
-
-
0032813516
-
On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease
-
Kollias, G., Douni, E., Kassiotis, G. and Kontoyiannis, D., On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease. Immunol. Rev. 1999. 169: 175-194.
-
(1999)
Immunol. Rev.
, vol.169
, pp. 175-194
-
-
Kollias, G.1
Douni, E.2
Kassiotis, G.3
Kontoyiannis, D.4
-
5
-
-
0024281428
-
A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF
-
Kriegler, M., Perez, C., DeFay, K., Albert, I. and Lu, S. D., A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: ramifications for the complex physiology of TNF. Cell 1988. 53: 45-53.
-
(1988)
Cell
, vol.53
, pp. 45-53
-
-
Kriegler, M.1
Perez, C.2
DeFay, K.3
Albert, I.4
Lu, S.D.5
-
6
-
-
0029114596
-
Two tumour necrosis factor receptors: Structure and function
-
Vandenabeele, P., Declercq, W., Beyaert, R. and Fiers, W., Two tumour necrosis factor receptors: structure and function. Trends Cell Biol. 1995. 5: 392-399.
-
(1995)
Trends Cell Biol.
, vol.5
, pp. 392-399
-
-
Vandenabeele, P.1
Declercq, W.2
Beyaert, R.3
Fiers, W.4
-
7
-
-
0028866022
-
The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor
-
Grell, M., Douni, E., Wajant, H., Lohden, M., Clauss, M., Maxeiner, B., Georgopoulos, S. et al., The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor. Cell 1995. 83: 793-802.
-
(1995)
Cell
, vol.83
, pp. 793-802
-
-
Grell, M.1
Douni, E.2
Wajant, H.3
Lohden, M.4
Clauss, M.5
Maxeiner, B.6
Georgopoulos, S.7
-
8
-
-
0032969285
-
Tumor necrosis factor receptor and Fas signaling mechanisms
-
Wallach, D., Varfolomeev, E. E., Malinin, N. L., Goltsev, Y. V., Kovalenko, A. V. and Boldin, M. P., Tumor necrosis factor receptor and Fas signaling mechanisms. Annu. Rev. Immunol. 1999. 17: 331-367.
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 331-367
-
-
Wallach, D.1
Varfolomeev, E.E.2
Malinin, N.L.3
Goltsev, Y.V.4
Kovalenko, A.V.5
Boldin, M.P.6
-
10
-
-
0031032891
-
Membrane protein secretases
-
Hooper, N. M., Karran, E. H. and Turner, A. J., Membrane protein secretases. Biochem. J. 1997. 321: 265-279.
-
(1997)
Biochem. J.
, vol.321
, pp. 265-279
-
-
Hooper, N.M.1
Karran, E.H.2
Turner, A.J.3
-
11
-
-
8044257704
-
A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells
-
Black, R. A., Rauch, C. T., Kozlosky, C. J., Peschon, J. J., Slack, J. L., Wolfson, M. F., Castner, B. J. et al., A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature 1997. 385: 729-733.
-
(1997)
Nature
, vol.385
, pp. 729-733
-
-
Black, R.A.1
Rauch, C.T.2
Kozlosky, C.J.3
Peschon, J.J.4
Slack, J.L.5
Wolfson, M.F.6
Castner, B.J.7
-
12
-
-
0031040432
-
Structural features and biochemical properties of TNF-alpha converting enzyme (TACE)
-
Moss, M. L., Jin, S. L., Becherer, J. D., Bickett, D. M., Burkhart, W., Chen, W. J., Hassler, D. et al., Structural features and biochemical properties of TNF-alpha converting enzyme (TACE). J. Neuroimmunol. 1997. 72: 127-129.
-
(1997)
J. Neuroimmunol.
, vol.72
, pp. 127-129
-
-
Moss, M.L.1
Jin, S.L.2
Becherer, J.D.3
Bickett, D.M.4
Burkhart, W.5
Chen, W.J.6
Hassler, D.7
-
13
-
-
0030698766
-
A murine transmembrane tumor necrosis factor (TNF) transgene induces arthritis by cooperative p55/p75 TNF receptor signaling
-
Alexopoulou, L., Pasparakis, M. and Kollias, G., A murine transmembrane tumor necrosis factor (TNF) transgene induces arthritis by cooperative p55/p75 TNF receptor signaling. Eur. J. Immunol. 1997. 27: 2588-2592.
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 2588-2592
-
-
Alexopoulou, L.1
Pasparakis, M.2
Kollias, G.3
-
14
-
-
0343505811
-
In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis
-
Kusters, S., Tiegs, G., Alexopoulou, L., Pasparakis, M., Douni, E., Kunstle, G., Bluethmann, H. et al., In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis. Eur. J. Immunol. 1997. 27: 2870-2875.
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 2870-2875
-
-
Kusters, S.1
Tiegs, G.2
Alexopoulou, L.3
Pasparakis, M.4
Douni, E.5
Kunstle, G.6
Bluethmann, H.7
-
15
-
-
0030639621
-
Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice
-
Akassoglou, K., Probert, L., Kontogeorgos, G. and Kollias, G., Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice. J. Immunol. 1997. 158: 438-445.
-
(1997)
J. Immunol.
, vol.158
, pp. 438-445
-
-
Akassoglou, K.1
Probert, L.2
Kontogeorgos, G.3
Kollias, G.4
-
16
-
-
0032541474
-
Complementation of lymphotoxin alpha knockout mice with tumor necrosis factor-expressing transgenes rectifies defective splenic structure and function
-
Alexopoulou, L., Pasparakis, M. and Kollias, G., Complementation of lymphotoxin alpha knockout mice with tumor necrosis factor-expressing transgenes rectifies defective splenic structure and function, J. Exp. Med. 1998. 188: 745-754.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 745-754
-
-
Alexopoulou, L.1
Pasparakis, M.2
Kollias, G.3
-
17
-
-
17944381638
-
Membrane-bound TNF supports secondary lymphoid organ structure but is subservient to secreted TNF in driving autoimmune inflammation
-
Ruuls, S. R., Hoek, R. M., Ngo, V. N., McNeil, T., Lucian, L. A., Janatpour, M. J., Korner, H. et al., Membrane-bound TNF supports secondary lymphoid organ structure but is subservient to secreted TNF in driving autoimmune inflammation. Immunity 2001. 15: 533-543.
-
(2001)
Immunity
, vol.15
, pp. 533-543
-
-
Ruuls, S.R.1
Hoek, R.M.2
Ngo, V.N.3
McNeil, T.4
Lucian, L.A.5
Janatpour, M.J.6
Korner, H.7
-
18
-
-
0035056003
-
Anti-TNF alpha therapy of rheumatoid arthritis: What have we learned?
-
Feldmann, M. and Maini, R. N., Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned? Annu. Rev. Immunol. 2001. 19: 163-196.
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 163-196
-
-
Feldmann, M.1
Maini, R.N.2
-
19
-
-
0035846326
-
Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent
-
Keane, J., Gershon, S., Wise, R. P., Mirabile-Levens, E., Kasznica, J., Schwieterman, W. D., Siegel, J. N. and Braun, M. M., Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. N. Engl. J. Med. 2001. 345: 1098-1104.
-
(2001)
N. Engl. J. Med.
, vol.345
, pp. 1098-1104
-
-
Keane, J.1
Gershon, S.2
Wise, R.P.3
Mirabile-Levens, E.4
Kasznica, J.5
Schwieterman, W.D.6
Siegel, J.N.7
Braun, M.M.8
-
20
-
-
0036822552
-
Life-threatening histoplasmosis complicating immunotherapy with tumor necrosis factor alpha antagonists infliximab and etanercept
-
Lee, J. H., Slifman, N. R., Gershon, S. K., Edwards, E. T., Schwieterman, W. D., Siegel, J. N., Wise, R. P. et al., Life-threatening histoplasmosis complicating immunotherapy with tumor necrosis factor alpha antagonists infliximab and etanercept. Arthritis Rheum. 2002. 46: 2565-2570.
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 2565-2570
-
-
Lee, J.H.1
Slifman, N.R.2
Gershon, S.K.3
Edwards, E.T.4
Schwieterman, W.D.5
Siegel, J.N.6
Wise, R.P.7
-
21
-
-
0037331223
-
Listeria monocytogenes infection as a complication of treatment with tumor necrosis factor alpha-neutralizing agents
-
Slifman, N. R., Gershon, S. K., Lee, J. H., Edwards, E. T. and Braun, M. M., Listeria monocytogenes infection as a complication of treatment with tumor necrosis factor alpha-neutralizing agents. Arthritis Rheum. 2003. 48: 319-324.
-
(2003)
Arthritis Rheum.
, vol.48
, pp. 319-324
-
-
Slifman, N.R.1
Gershon, S.K.2
Lee, J.H.3
Edwards, E.T.4
Braun, M.M.5
-
22
-
-
0036673687
-
Pneumocystis carinii pneumonia following a second infusion of infliximab
-
Tai, T. L., O'Rourke, K. P., McWeeney, M., Burke, C. M., Sheehan, K. and Barry, M., Pneumocystis carinii pneumonia following a second infusion of infliximab. Rheumatology (Oxford) 2002. 41: 951-952.
-
(2002)
Rheumatology (Oxford)
, vol.41
, pp. 951-952
-
-
Tai, T.L.1
O'Rourke, K.P.2
McWeeney, M.3
Burke, C.M.4
Sheehan, K.5
Barry, M.6
-
23
-
-
0037116836
-
Drug-induced systemic lupus erythematosus associated with etanercept therapy
-
Shakoor, N., Michalska, M., Harris, C. A. and Block, J. A., Drug-induced systemic lupus erythematosus associated with etanercept therapy. Lancet 2002. 359: 579-580.
-
(2002)
Lancet
, vol.359
, pp. 579-580
-
-
Shakoor, N.1
Michalska, M.2
Harris, C.A.3
Block, J.A.4
-
24
-
-
0033546665
-
TNF neutralization in MS: Results of a randomized, placebo-controlled multicenter study
-
The Lenercept Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group
-
TNF neutralization in MS: results of a randomized, placebo-controlled multicenter study. The Lenercept Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group. Neurology 1999. 53: 457-465.
-
(1999)
Neurology
, vol.53
, pp. 457-465
-
-
-
25
-
-
0029751983
-
Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2
-
van Oosten, B. W., Barkhof, F., Truyen, L., Boringa, J. B., Bertelsmann, F. W., von Blomberg, B. M., Woody, J. N. et al., Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2. Neurology 1996. 47: 1531-1534.
-
(1996)
Neurology
, vol.47
, pp. 1531-1534
-
-
van Oosten, B.W.1
Barkhof, F.2
Truyen, L.3
Boringa, J.B.4
Bertelsmann, F.W.5
von Blomberg, B.M.6
Woody, J.N.7
-
26
-
-
4944223125
-
Unusual toxicities with TNF inhibition: Heart failure and drug-induced lupus
-
Cush, J. J., Unusual toxicities with TNF inhibition: heart failure and drug-induced lupus. Clin. Exp. Rheumatol. 2004. 22: S141-147.
-
(2004)
Clin. Exp. Rheumatol.
, vol.22
-
-
Cush, J.J.1
-
27
-
-
0036900501
-
Tumor necrosis factor antagonist therapy and lymphoma development: Twenty-six cases reported to the Food and Drug Administration
-
Brown, S. L., Greene, M. H., Gershon, S. K., Edwards, E. T. and Braun, M. M., Tumor necrosis factor antagonist therapy and lymphoma development: twenty-six cases reported to the Food and Drug Administration. Arthritis Rheum. 2002. 46: 3151-3158.
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 3151-3158
-
-
Brown, S.L.1
Greene, M.H.2
Gershon, S.K.3
Edwards, E.T.4
Braun, M.M.5
-
28
-
-
0035179804
-
Rapid onset of cutaneous squamous cell carcinoma in patients with rheumatoid arthritis after starting tumor necrosis factor alpha receptor IgGl-Fc fusion complex therapy
-
Smith, K. J. and Skelton, H. G., Rapid onset of cutaneous squamous cell carcinoma in patients with rheumatoid arthritis after starting tumor necrosis factor alpha receptor IgGl-Fc fusion complex therapy. J. Am. Acad. Dermatol. 2001. 45: 953-956.
-
(2001)
J. Am. Acad. Dermatol.
, vol.45
, pp. 953-956
-
-
Smith, K.J.1
Skelton, H.G.2
-
29
-
-
0038772008
-
Tumor necrosis factor biology in experimental and clinical arthritis
-
Sfikakis, P. P. and Kollias, G., Tumor necrosis factor biology in experimental and clinical arthritis. Curr. Opin. Rheumatol. 2003. 15: 380-386.
-
(2003)
Curr. Opin. Rheumatol.
, vol.15
, pp. 380-386
-
-
Sfikakis, P.P.1
Kollias, G.2
-
30
-
-
0036694562
-
Role of TNF/TNFR in autoimmunity: Specific TNF receptor blockade may be advantageous to anti-TNF treatments
-
Kollias, G. and Kontoyiannis, D., Role of TNF/TNFR in autoimmunity: specific TNF receptor blockade may be advantageous to anti-TNF treatments. Cytokine Growth Factor Rev. 2002. 13: 315-321.
-
(2002)
Cytokine Growth Factor Rev.
, vol.13
, pp. 315-321
-
-
Kollias, G.1
Kontoyiannis, D.2
-
31
-
-
0029989339
-
Immune and inflammatory responses in TNF alpha-deficient mice: A critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response
-
Pasparakis, M., Alexopoulou, L., Episkopou, V. and Kollias, G., Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response. J. Exp. Med. 1996. 184: 1397-1411.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1397-1411
-
-
Pasparakis, M.1
Alexopoulou, L.2
Episkopou, V.3
Kollias, G.4
-
32
-
-
0027450436
-
Mixed haplotypes and autoimmunity
-
Nygard, N. R., McCarthy, D. M., Schiffenbauer, J. and Schwartz, B. D., Mixed haplotypes and autoimmunity. Immunol. Today 1993. 14: 53-56.
-
(1993)
Immunol. Today
, vol.14
, pp. 53-56
-
-
Nygard, N.R.1
McCarthy, D.M.2
Schiffenbauer, J.3
Schwartz, B.D.4
-
33
-
-
0033947471
-
Accelerated autoimmunity and lupus nephritis in NZB mice with an engineered heterozygous deficiency in tumor necrosis factor
-
Kontoyiannis, D. and Kollias, G., Accelerated autoimmunity and lupus nephritis in NZB mice with an engineered heterozygous deficiency in tumor necrosis factor. Eur. J. Immunol. 2000. 30: 2038-2047.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 2038-2047
-
-
Kontoyiannis, D.1
Kollias, G.2
-
34
-
-
0035910751
-
Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: Implications for pathogenesis and therapy of autoimmune demyelination
-
Kassiotis, G. and Kollias, G., Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: implications for pathogenesis and therapy of autoimmune demyelination. J. Exp. Med. 2001. 193: 427-434.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 427-434
-
-
Kassiotis, G.1
Kollias, G.2
-
35
-
-
28044445089
-
Membrane TNF confers protection to acute mycobacterial infection
-
Fremond, C., Dambusza, L, Allie, N., Jacobs, M., Grivennikov, S., Quesniaux, V. F. and Ryffel, B., Membrane TNF confers protection to acute mycobacterial infection. Respir. Res. 2005. 6: 136.
-
(2005)
Respir. Res.
, vol.6
, pp. 136
-
-
Fremond, C.1
Dambusza, L.2
Allie, N.3
Jacobs, M.4
Grivennikov, S.5
Quesniaux, V.F.6
Ryffel, B.7
-
36
-
-
0029164968
-
Generation and biological characterization of membrane-bound, uncleavable murine tumor necrosis factor
-
Decoster, E., Vanhaesebroeck, B., Vandenabeele, P., Grooten, J. and Fiers, W., Generation and biological characterization of membrane-bound, uncleavable murine tumor necrosis factor. J. Biol. Chem. 1995. 270: 18473-18478.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18473-18478
-
-
Decoster, E.1
Vanhaesebroeck, B.2
Vandenabeele, P.3
Grooten, J.4
Fiers, W.5
-
37
-
-
0023175468
-
Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and d-galactosa-mine-treated mice
-
Lehmann, V., Freudenberg, M. A. and Galanos, C., Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and d-galactosa-mine-treated mice. J. Exp. Med. 1987. 165: 657-663.
-
(1987)
J. Exp. Med.
, vol.165
, pp. 657-663
-
-
Lehmann, V.1
Freudenberg, M.A.2
Galanos, C.3
-
38
-
-
0027297663
-
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
-
Pfeffer, K., Matsuyama, T., Kundig, T. M., Wakeham, A., Kishihara, K., Shahinian, A., Wiegmann, K. et al., Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 1993. 73: 457-467.
-
(1993)
Cell
, vol.73
, pp. 457-467
-
-
Pfeffer, K.1
Matsuyama, T.2
Kundig, T.M.3
Wakeham, A.4
Kishihara, K.5
Shahinian, A.6
Wiegmann, K.7
-
39
-
-
0027327619
-
Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes
-
Rothe, J., Lesslauer, W., Lotscher, H., Lang, Y., Koebel, P., Kontgen, F., Althage, A. et al., Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes. Nature 1993. 364: 798-802.
-
(1993)
Nature
, vol.364
, pp. 798-802
-
-
Rothe, J.1
Lesslauer, W.2
Lotscher, H.3
Lang, Y.4
Koebel, P.5
Kontgen, F.6
Althage, A.7
-
40
-
-
0028485654
-
Processing of tumour necrosis factor-alpha precursor by metalloproteinases
-
Gearing, A. J., Beckett, P., Christodoulou, M., Churchill, M., Clements, J., Davidson, A. H., Drummond, A. H. et al., Processing of tumour necrosis factor-alpha precursor by metalloproteinases. Nature 1994. 370: 555-557.
-
(1994)
Nature
, vol.370
, pp. 555-557
-
-
Gearing, A.J.1
Beckett, P.2
Christodoulou, M.3
Churchill, M.4
Clements, J.5
Davidson, A.H.6
Drummond, A.H.7
-
41
-
-
0031974459
-
TNF receptor type 2 mediates thymocyte proliferation independently of TNF receptor type 1
-
Grell, M., Becke, F. M., Wajant, H., Mannel, D. N. and Scheurich, P., TNF receptor type 2 mediates thymocyte proliferation independently of TNF receptor type 1. Eur. J. Immunol. 1998. 28: 257-263.
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 257-263
-
-
Grell, M.1
Becke, F.M.2
Wajant, H.3
Mannel, D.N.4
Scheurich, P.5
-
42
-
-
0031008477
-
Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor
-
Pasparakis, M., Alexopoulou, L., Grell, M., Pfizenmaier, K., Bluethmann, H. and Kollias, G., Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor. Proc. Natl. Acad. Sci. USA 1997. 94: 6319-6323.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6319-6323
-
-
Pasparakis, M.1
Alexopoulou, L.2
Grell, M.3
Pfizenmaier, K.4
Bluethmann, H.5
Kollias, G.6
-
43
-
-
0031985413
-
TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation
-
Peschon, J. J., Torrance, D. S., Stocking, K. L., Glaccum, M. B., Otten, C., Willis, C. R., Charrier, K. et al., TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation. J. Immunol. 1998. 160: 943-952.
-
(1998)
J. Immunol.
, vol.160
, pp. 943-952
-
-
Peschon, J.J.1
Torrance, D.S.2
Stocking, K.L.3
Glaccum, M.B.4
Otten, C.5
Willis, C.R.6
Charrier, K.7
-
44
-
-
17044368806
-
Transmembrane TNF is sufficient to initiate cell migration and granuloma formation and provide acute, but not long-term, control of Mycobacterium tuberculosis infection
-
Saunders, B. M., Tran, S., Ruuls, S., Sedgwick, J. D., Briscoe, H. and Britton, W. J., Transmembrane TNF is sufficient to initiate cell migration and granuloma formation and provide acute, but not long-term, control of Mycobacterium tuberculosis infection. J. Immunol. 2005. 174: 4852-4859.
-
(2005)
J. Immunol.
, vol.174
, pp. 4852-4859
-
-
Saunders, B.M.1
Tran, S.2
Ruuls, S.3
Sedgwick, J.D.4
Briscoe, H.5
Britton, W.J.6
-
45
-
-
16044369031
-
A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency
-
Taylor, G. A., Carballo, E., Lee, D. M., Lai, W. S., Thompson, M, J., Patel, D. D., Schenkman, D. I. et al., A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency. Immunity 1996. 4: 445-454.
-
(1996)
Immunity
, vol.4
, pp. 445-454
-
-
Taylor, G.A.1
Carballo, E.2
Lee, D.M.3
Lai, W.S.4
Thompson, M.J.5
Patel, D.D.6
Schenkman, D.I.7
-
46
-
-
0035889121
-
Roles of tumor necrosis factor-alpha receptor subtypes in the pathogenesis of the tristetraprolin-deficiency syndrome
-
Carballo, E. and Blackshear, P. J., Roles of tumor necrosis factor-alpha receptor subtypes in the pathogenesis of the tristetraprolin-deficiency syndrome. Blood 2001. 98: 2389-2395.
-
(2001)
Blood
, vol.98
, pp. 2389-2395
-
-
Carballo, E.1
Blackshear, P.J.2
-
47
-
-
0030882906
-
Bone marrow transplantation reproduces the tristetraprolin-deficiency syndrome in recombination activating gene-2 (-/-) mice. Evidence that monocyte/macrophage progenitors may be responsible for TNFalpha overproduction
-
Carballo, E., Gilkeson, G. S. and Blackshear, P. J., Bone marrow transplantation reproduces the tristetraprolin-deficiency syndrome in recombination activating gene-2 (-/-) mice. Evidence that monocyte/ macrophage progenitors may be responsible for TNFalpha overproduction. J. Clin. Invest. 1997. 100: 986-995.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 986-995
-
-
Carballo, E.1
Gilkeson, G.S.2
Blackshear, P.J.3
-
48
-
-
0038917435
-
Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting
-
Korner, H., Riminton, D. S., Strickland, D. H., Lemckert, F. A., Pollard, J. D. and Sedgwick, J. D., Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting. J. Exp. Med. 1997. 186: 1585-1590.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1585-1590
-
-
Korner, H.1
Riminton, D.S.2
Strickland, D.H.3
Lemckert, F.A.4
Pollard, J.D.5
Sedgwick, J.D.6
-
49
-
-
0033024388
-
TNF accelerates the onset but does not alter the incidence and severity of myelin basic protein-induced experimental autoimmune encephalomyelitis
-
Kassiotis, G., Pasparakis, M., Kollias, G. and Probert, L., TNF accelerates the onset but does not alter the incidence and severity of myelin basic protein-induced experimental autoimmune encephalomyelitis. Eur. J. Immunol, 1999. 29: 774-780.
-
(1999)
Eur. J. Immunol
, vol.29
, pp. 774-780
-
-
Kassiotis, G.1
Pasparakis, M.2
Kollias, G.3
Probert, L.4
-
50
-
-
0033032129
-
Severity of symptoms and demyelination in MOG-induced EAE depends on TNFR1
-
Eugster, H. P., Frei, K., Bachmann, R., Bluethmann, H., Lassmann, H. and Fontana, A., Severity of symptoms and demyelination in MOG-induced EAE depends on TNFR1. Eur. J. Immunol. 1999. 29: 626-632.
-
(1999)
Eur. J. Immunol.
, vol.29
, pp. 626-632
-
-
Eugster, H.P.1
Frei, K.2
Bachmann, R.3
Bluethmann, H.4
Lassmann, H.5
Fontana, A.6
-
51
-
-
0035479122
-
Defective CD4T cell priming and resistance to experimental autoimmune encephalomyelitis in TNF-deficient mice due to innate immune hypo-responsiveness
-
Kassiotis, G., Kranidioti, K. and Kollias, G., Defective CD4T cell priming and resistance to experimental autoimmune encephalomyelitis in TNF-deficient mice due to innate immune hypo-responsiveness. J. Neuroimmunol. 2001. 119: 239-247.
-
(2001)
J. Neuroimmunol.
, vol.119
, pp. 239-247
-
-
Kassiotis, G.1
Kranidioti, K.2
Kollias, G.3
-
52
-
-
0026039673
-
Transgenic mice expressing human tumour necrosis factor: A predictive genetic model of arthritis
-
Keffer, J., Probert, L., Cazlaris, H., Georgopoulos, S., Kaslaris, E., Kioussis, D. and Kollias, G., Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. EMBO J. 1991. 10: 4025-4031.
-
(1991)
EMBO J.
, vol.10
, pp. 4025-4031
-
-
Keffer, J.1
Probert, L.2
Cazlaris, H.3
Georgopoulos, S.4
Kaslaris, E.5
Kioussis, D.6
Kollias, G.7
-
53
-
-
0033103805
-
Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: Implications for joint and gut-associated immunopathologies
-
Kontoyiannis, D., Pasparakis, M., Pizarro, T. T., Cominelli, F. and Kollias, G., Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies. Immunity 1999. 10: 387-398.
-
(1999)
Immunity
, vol.10
, pp. 387-398
-
-
Kontoyiannis, D.1
Pasparakis, M.2
Pizarro, T.T.3
Cominelli, F.4
Kollias, G.5
-
54
-
-
0037955831
-
Anti-cytokine therapeutics and infections
-
Dinarello, C. A., Anti-cytokine therapeutics and infections. Vaccine 2003. 21 Suppl 2: S24-34.
-
(2003)
Vaccine
, vol.21
, Issue.SUPPL. 2
-
-
Dinarello, C.A.1
-
55
-
-
0032488990
-
Induction of unresponsiveness to tumor necrosis factor (TNF) after autocrine TNF expression requires TNF membrane retention
-
Decoster, E., Vanhaesebroeck, B., Boone, E., Plaisance, S., De Vos, K., Haegeman, G., Grooten, J. and Fiers, W., Induction of unresponsiveness to tumor necrosis factor (TNF) after autocrine TNF expression requires TNF membrane retention. J. Biol. Chem. 1998. 273: 3271-3277.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 3271-3277
-
-
Decoster, E.1
Vanhaesebroeck, B.2
Boone, E.3
Plaisance, S.4
De Vos, K.5
Haegeman, G.6
Grooten, J.7
Fiers, W.8
-
56
-
-
0033006011
-
Development and maturation of secondary lymphoid tissues
-
Fu, Y. X. and Chaplin, D. D., Development and maturation of secondary lymphoid tissues. Annu. Rev. Immunol. 1999. 17: 399-433.
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 399-433
-
-
Fu, Y.X.1
Chaplin, D.D.2
-
57
-
-
0028979703
-
Tumor necrosis factor-alpha is required in the protective immune response
-
Flynn, J. L., Goldstein, M. M., Chan, J., Triebold, K. J., Pfeffer, K., Lowenstein, C. J., Schreiber, R. et al., Tumor necrosis factor-alpha is required in the protective immune response. Immunity 1995. 2: 561-572.
-
(1995)
Immunity
, vol.2
, pp. 561-572
-
-
Flynn, J.L.1
Goldstein, M.M.2
Chan, J.3
Triebold, K.J.4
Pfeffer, K.5
Lowenstein, C.J.6
Schreiber, R.7
-
58
-
-
28244444594
-
Membrane tumor necrosis factor confers partial protection to listeria infection
-
Torres, D., Janot, L., Quesniaux, V. F., Grivennikov, S. L, Maillet, L, Sedgwick, J. D., Ryffel, B. and Erard, F., Membrane tumor necrosis factor confers partial protection to listeria infection. Am. J. Pathol. 2005. 167: 1677-1687.
-
(2005)
Am. J. Pathol.
, vol.167
, pp. 1677-1687
-
-
Torres, D.1
Janot, L.2
Quesniaux, V.F.3
Grivennikov, S.L.4
Maillet, L.5
Sedgwick, J.D.6
Ryffel, B.7
Erard, F.8
-
59
-
-
12144287462
-
Identification and characterization of 4-[[4-(2-butynyloxy)phenyl]- sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpho linecarboxamide (TMI-1), a novel dual tumor necrosis factor- alpha-converting enzyme/matrix metalloprotease inhibitor for the treatment of rheumatoid arthritis
-
Zhang, Y., Xu, J., Levin, J., Hegen, M., Li, G., Robertshaw, H., Brennan, F. et al., Identification and characterization of 4- 4-(2-butynyloxy)phenyl]-sulfonyl]- N-hydroxy-2,2-dimethyl-(3S)thiomorpho linecarboxamide (TMI-1), a novel dual tumor necrosis factor-alpha-converting enzyme/matrix metalloprotease inhibitor for the treatment of rheumatoid arthritis. J. Pharmacol. Exp. Ther. 2004. 309: 348-355.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.309
, pp. 348-355
-
-
Zhang, Y.1
Xu, J.2
Levin, J.3
Hegen, M.4
Li, G.5
Robertshaw, H.6
Brennan, F.7
-
60
-
-
28544452195
-
A role for the phagosome in cytokine secretion
-
Murray, R. Z., Kay, J. G., Sangermani, D. G. and Stow, J. L., A role for the phagosome in cytokine secretion. Science 2005. 310: 1492-1495.
-
(2005)
Science
, vol.310
, pp. 1492-1495
-
-
Murray, R.Z.1
Kay, J.G.2
Sangermani, D.G.3
Stow, J.L.4
-
61
-
-
0030240573
-
Genetic analysis of susceptibility to experimental autoimmune encephalomyelitis in a cross between SJL/J and B10.S mice
-
Encinas, J. A., Lees, M. B., Sobel, R. A., Symonowicz, C., Greer, J. M., Shoviin, C. L., Weiner, H. L. et al., Genetic analysis of susceptibility to experimental autoimmune encephalomyelitis in a cross between SJL/J and B10.S mice. J. Immunol. 1996. 157. 2186-2192.
-
(1996)
J. Immunol.
, vol.157
, pp. 2186-2192
-
-
Encinas, J.A.1
Lees, M.B.2
Sobel, R.A.3
Symonowicz, C.4
Greer, J.M.5
Shoviin, C.L.6
Weiner, H.L.7
-
62
-
-
0030918326
-
Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis
-
Frei, K., Eugster, H. P., Bopst, M., Constantinescu, C. S., Lavi, E. and Fontana, A., Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis. J. Exp. Med. 1997. 185: 2177-2182.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 2177-2182
-
-
Frei, K.1
Eugster, H.P.2
Bopst, M.3
Constantinescu, C.S.4
Lavi, E.5
Fontana, A.6
-
63
-
-
0028864801
-
Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha
-
Probert, L., Akassoglou, K., Pasparakis, M., Kontogeorgos, G. and Kollias, G., Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha. Proc. Natl. Acad. Sci. USA 1995. 92: 11294-11298.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 11294-11298
-
-
Probert, L.1
Akassoglou, K.2
Pasparakis, M.3
Kontogeorgos, G.4
Kollias, G.5
-
64
-
-
0028059099
-
Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
-
Gu, H., Marth, J. D., Orban, P. C., Mossmann, H. and Rajewsky, K., Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science 1994. 265: 103-106.
-
(1994)
Science
, vol.265
, pp. 103-106
-
-
Gu, H.1
Marth, J.D.2
Orban, P.C.3
Mossmann, H.4
Rajewsky, K.5
-
65
-
-
0025780879
-
Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene
-
Tybulewicz, V. L., Crawford, C. E., Jackson, P. K., Bronson, R. T. and Mulligan, R. C., Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell 1991. 65: 1153-1163.
-
(1991)
Cell
, vol.65
, pp. 1153-1163
-
-
Tybulewicz, V.L.1
Crawford, C.E.2
Jackson, P.K.3
Bronson, R.T.4
Mulligan, R.C.5
-
66
-
-
0022461705
-
Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector
-
Robertson, E., Bradley, A., Kuehn, M. and Evans, M., Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector. Nature 1986. 323: 445-448.
-
(1986)
Nature
, vol.323
, pp. 445-448
-
-
Robertson, E.1
Bradley, A.2
Kuehn, M.3
Evans, M.4
-
67
-
-
0003069605
-
Production of cytokine transgenic and knockout mice
-
In Balkwill, F. R. (Ed.) Oxford University Press, Oxford
-
Pasparakis, M. and Kollias, G., Production of cytokine transgenic and knockout mice. In Balkwill, F. R. (Ed.) Cytokines: A Practical Approach. Oxford University Press, Oxford 1995, pp 297-324.
-
(1995)
Cytokines: A Practical Approach
, pp. 297-324
-
-
Pasparakis, M.1
Kollias, G.2
-
68
-
-
0028928854
-
Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase
-
Araki, K., Araki, M., Miyazaki, J. and Vassalli, P., Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase. Proc. Natl. Acad. Sci. USA 1995. 92: 160-164.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 160-164
-
-
Araki, K.1
Araki, M.2
Miyazaki, J.3
Vassalli, P.4
-
69
-
-
0027280936
-
Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting
-
Gu, H., Zou, Y. R. and Rajewsky, K., Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting. Cell 1993. 73: 1155-1164.
-
(1993)
Cell
, vol.73
, pp. 1155-1164
-
-
Gu, H.1
Zou, Y.R.2
Rajewsky, K.3
-
70
-
-
0024464468
-
Listeriolysin O is essential for virulence of Listeria monocytogenes: Direct evidence obtained by gene complementation
-
Cossart, P., Vicente, M. F., Mengaud, J., Baquero, F., Perez-Diaz, J. C. and Berche, P., Listeriolysin O is essential for virulence of Listeria monocytogenes: direct evidence obtained by gene complementation. Infect. Immun. 1989. 57: 3629-3636.
-
(1989)
Infect. Immun.
, vol.57
, pp. 3629-3636
-
-
Cossart, P.1
Vicente, M.F.2
Mengaud, J.3
Baquero, F.4
Perez-Diaz, J.C.5
Berche, P.6
|