Mechanisms of PEDF-mediated protection against reactive oxygen species damage in diabetic retinopathy and neuropathy

Journal of Endocrinology

Volumn 222, Issue 3, 2014, Pages 129-139

  Elahy, Mina ^a   Baindur Hudson, Swati ^a   Cruzat, Vinicius F ^b   Newsholme, Philip ^b   Dass, Crispin R ^b  

^a VICTORIA UNIVERSITY   (Australia)

^b CURTIN UNIVERSITY   (Australia)

Author keywords

Diabetes; Oxidative stress; PEDF; Pericyte; Redox balance; Signal transduction

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; DNA; FREE RADICAL; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIGMENT EPITHELIUM DERIVED FACTOR; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; RECOMBINANT PIGMENT EPITHELIUM DERIVED FACTOR; RECOMBINANT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; STAT3 PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN; ANTIOXIDANT; BAX PROTEIN, HUMAN; EYE PROTEIN; NERVE GROWTH FACTOR; NEUROPROTECTIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PIGMENT EPITHELIUM-DERIVED FACTOR; SERINE PROTEINASE INHIBITOR;

ANGIOGENESIS; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; CELL COMMUNICATION; DIABETIC NEUROPATHY; DIABETIC RETINOPATHY; DNA DAMAGE; DOPAMINERGIC NERVE CELL; DRUG EFFICACY; DRUG INHIBITION; ENDOTHELIUM CELL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MEDIATOR; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PERICYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA; REVIEW; SIGNAL TRANSDUCTION; BIOLOGICAL MODEL; DIABETIC NEUROPATHIES; METABOLISM;

ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; DIABETIC NEUROPATHIES; DIABETIC RETINOPATHY; ENDOTHELIAL CELLS; EYE PROTEINS; HUMANS; INFLAMMATION; MODELS, BIOLOGICAL; NADP; NERVE GROWTH FACTORS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PERICYTES; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; SERPINS; SIGNAL TRANSDUCTION;

EID: 84907308232     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-14-0065     Document Type: Review

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