Pigment epithelium-derived factor (PEDF) blocks the interleukin-6 signaling to C-reactive protein expression in Hep3B cells by suppressing Rac-1 activation

Life Sciences

Volumn 79, Issue 21, 2006, Pages 1981-1987

  Yoshida, Takafumi ^a   Yamagishi, Sho ichi ^a   Nakamura, Kazuo ^a   Matsui, Takanori ^a   Imaizumi, Tsutomu ^a   Inoue, Hiroyoshi ^a   Ueno, Takato ^a   Sata, Michio ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Abs; antibodies; Atherosclerosis; C reactive protein; CRP; diphenylene iodonium; dithiothreitol; DPI; DTT; EC; endothelial cells; IL 1 ; IL 6; interleukin 1 .; interleukin 6; Interleukin 6; JAK; Janus kinase; N acetylcysteine; NAC; Oxidative stress; PEDF; pigment epithelium derived factor; reactive oxygen species; reverse transcription polymerase chain reaction; ROS; RT PCR; signal transducer and activator of transcription; STAT

Indexed keywords

C REACTIVE PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MESSENGER RNA; PIGMENT EPITHELIUM DERIVED FACTOR; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN;

ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; DOSE RESPONSE; HEPATOMA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANTIBODIES, MONOCLONAL; C-REACTIVE PROTEIN; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; EYE PROTEINS; HUMANS; INTERLEUKIN-6; NERVE GROWTH FACTORS; NF-KAPPA B; RAC1 GTP-BINDING PROTEIN; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SERPINS; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 33749530501     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2006.06.034     Document Type: Article

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