Chitosan microparticles encapsulating PEDF plasmid demonstrate efficacy in an orthotopic metastatic model of osteosarcoma

Biomaterials

Volumn 28, Issue 19, 2007, Pages 3026-3033

  Dass, Crispin R ^a   Contreras, Karla G ^a   Dunstan, David E ^a   Choong, Peter F M ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b PETER MACCALLUM CANCER CENTRE   (Australia)

Author keywords

Cancer; Chitosan; Gene delivery; Microparticle; PEDF

Indexed keywords

DISEASES; ELECTRON MICROSCOPY; ENCAPSULATION; MATHEMATICAL MODELS; MICROSTRUCTURE; ONCOLOGY; TUMORS;

CHITOSAN; GENE DELIVERY; MICROPARTICLES;

CHITIN;

CHITOSAN; GREEN FLUORESCENT PROTEIN; PIGMENT EPITHELIUM DERIVED FACTOR; PLASMID VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BONE METASTASIS; CANCER CELL CULTURE; CANCER GENE THERAPY; CELL ADHESION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; ELECTRON MICROSCOPE; ELECTROPORATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUNG METASTASIS; MICROENCAPSULATION; MOUSE; NONHUMAN; OSTEOLYSIS; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH;

ANGIOGENESIS INHIBITORS; ANIMALS; BONE NEOPLASMS; CELL LINE, TUMOR; CHITOSAN; DRUG COMPOUNDING; EYE PROTEINS; FEMALE; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HUMANS; LUNG NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM METASTASIS; NERVE GROWTH FACTORS; OSTEOSARCOMA; PARTICLE SIZE; PLASMIDS; SERPINS; TRANSFECTION;

EID: 34147185229     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2007.03.016     Document Type: Article

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