Pigment epithelium-derived factor (PEDF) protects cortical neurons in vitro from oxidant injury by activation of extracellular signal-regulated kinase (ERK) 1/2 and induction of Bcl-2

Neuroscience Research

Volumn 72, Issue 1, 2012, Pages 1-8

  Sanchez, A ^a   Tripathy, D ^a   Yin, X ^a   Luo, J ^a   Martinez, J ^a   Grammas, P ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Apoptosis; ERK; Neurons; Neurotrophic; Oxidative stress; PEDF; PI3K Akt

Indexed keywords

CASPASE 3; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PIGMENT EPITHELIUM DERIVED FACTOR; PROTEIN BCL 2; RECOMBINANT PROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CELL ACTIVATION; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; IN VITRO STUDY; NERVE CELL CULTURE; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; RAT;

ANIMALS; APOPTOSIS; CASPASE 3; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; EYE PROTEINS; HYDROGEN PEROXIDE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NERVE GROWTH FACTORS; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; SERPINS;

EID: 83155175160     PISSN: 01680102     EISSN: 18728111     Source Type: Journal    
DOI: 10.1016/j.neures.2011.09.003     Document Type: Article

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