Pigment epithelium-derived factor induces interleukin-10 expression in human macrophages by induction of PPAR gamma

Life Sciences

Volumn 87, Issue 1-2, 2010, Pages 26-35

  Yang, Su Lin ^a   Chen, Show Li ^b   Wu, Ju Yun ^c,d   Ho, Tsung Chuan ^c   Tsao, Yeou Ping ^c,d  

^a Centers for Disease Control   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c MACKAY MEMORIAL HOSPITAL   (Taiwan)

^d NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

Anti inflammation; MAPK signaling; PPREs; Transcriptional regulation

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACTIVATING TRANSCRIPTION FACTOR 2; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CIGLITAZONE; CYCLOHEXIMIDE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIGMENT EPITHELIUM DERIVED FACTOR; TRANSCRIPTION FACTOR ELK 1; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; MACROPHAGE; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

CELL LINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; EYE PROTEINS; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; IMMUNOBLOTTING; INTERLEUKIN-10; MACROPHAGES; MITOGEN-ACTIVATED PROTEIN KINASE 1; NERVE GROWTH FACTORS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; POLYMERASE CHAIN REACTION; PPAR GAMMA; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SERPINS; TRANSCRIPTION, GENETIC;

EID: 77953958538     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2010.05.007     Document Type: Article

References (40)

1. Arimura N., Horiba T., Imagawa M., Shimizu M., Sato R. The peroxisome proliferator-activated receptor gamma regulates expression of the perilipin gene in adipocytes. Journal of Biological Chemistry 2004, 279(11):10070-10076.
2. Armoni M., Harel C., Karni S., Chen H., Bar-Yoseph F., Ver M.R., Quon M.J., Karnieli E. FOXO1 represses peroxisome proliferator-activated receptor-gamma1 and -gamma2 gene promoters in primary adipocytes. A novel paradigm to increase insulin sensitivity. Journal of Biological Chemistry 2006, 281(29):19881-19891.
3. Asada S., Daitoku H., Matsuzaki H., Saito T., Sudo T., Mukai H., Iwashita S., Kako K., Kishi T., Kasuya Y., Fukamizu A. Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1. Cellular Signalling 2007, 19(3):519-527.
4. Bernard A., Gao-Li J., Franco C.A., Bouceba T., Huet A., Li Z. Laminin receptor involvement in the anti-angiogenic activity of pigment epithelium-derived factor. Journal of Biological Chemistry 2009, 284(16):10480-10490.
5. Chen L., Zhang S.S., Barnstable C.J., Tombran-Tink J. PEDF induces apoptosis in human endothelial cells by activating p38 MAP kinase dependent cleavage of multiple caspases. Biochemical and Biophysical Research Communications 2006, 348(4):1288-1295.
6. Chinetti G., Griglio S., Antonucci M., Torra I.P., Delerive P., Majd Z., Fruchart J.C., Chapman J., Najib J., Staels B. Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages. Journal of Biological Chemistry 1998, 273(40):25573-25580.
7. Chung E.Y., Liu J., Homma Y., Zhang Y., Brendolan A., Saggese M., Han J., Silverstein R., Selleri L., Ma X. Interleukin-10 expression in macrophages during phagocytosis of apoptotic cells is mediated by homeodomain proteins Pbx1 and Prep-1. Immunity 2007, 27(6):952-964.
8. Csóka B., Németh Z.H., Virág L., Gergely P., Leibovich S.J., Pacher P., Sun C.X., Blackburn M.R., Vizi E.S., Deitch E.A., Haskó G. A2A adenosine receptors and C/EBPbeta are crucially required for IL-10 production by macrophages exposed to Escherichia coli. Blood 2007, 110(7):2685-2695.
9. Dawson D.W., Volpert O.V., Gillis P., Crawford S.E., Xu H., Benedict W., Bouck N.P. Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Science 1999, 285(5425):245-248.
10. Filleur S., Volz K., Nelius T., Mirochnik Y., Huang H., Zaichuk T.A., Aymerich M.S., Becerra S.P., Yap R., Veliceasa D., Shroff E.H., Volpert O.V. Two functional epitopes of pigment epithelial-derived factor block angiogenesis and induce differentiation in prostate cancer. Cancer Research 2005, 65(12):5144-5152.
11. Gogolak P., Rethi B., Szatmari I., Lanyi A., Dezso B., Nagy L., Rajnavolgyi E. Differentiation of CD1a- and CD1a+ monocyte-derived dendritic cells is biased by lipid environment and PPARgamma. Blood 2007, 109(2):643-652.
12. Hihi A.K., Michalik L., Wahli W. PPARs: transcriptional effectors of fatty acids and their derivatives. Cellular and Molecular Life Sciences 2002, 59(5):790-798.
13. Ho T.C., Chen S.L., Yang Y.C., Liao C.L., Cheng H.C., Tsao Y.P. PEDF induces p53-mediated apoptosis through PPAR gamma signaling in human umbilical vein endothelial cells. Cardiovascular Research 2007, 76(2):213-223.
14. Ho T.C., Yang Y.C., Chen S.L., Kuo P.C., Sytwu H.K., Cheng H.C., Tsao Y.P. Pigment epithelium-derived factor induces THP-1 macrophage apoptosis and necrosis by the induction of the peroxisome proliferator-activated receptor gamma. Molecular Immunology 2008, 45(4):898-909.
15. Ho T.C., Chen S.L., Yang Y.C., Chen C.Y., Feng F.P., Hsieh J.W., Cheng H.C., Tsao Y.P. 15-Deoxy-delta(12, 14)-prostaglandin J2 induces vascular endothelial cell apoptosis through the sequential activation of MAPKS and p53. Journal of Biological Chemistry 2008, 283(44):30273-30288.
16. Ho T.C., Chen S.L., Yang Y.C., Lo T.H., Hsieh J.W., Cheng H.C., Tsao Y.P. Cytosolic phospholipase A2-{alpha} is an early apoptotic activator in PEDF-induced endothelial cell apoptosis. American journal of physiology. Cell physiology 2009, 296(2):C273-284.
17. Lucas M., Zhang X., Prasanna V., Mosser D.M. ERK activation following macrophage FcgammaR ligation leads to chromatin modifications at the IL-10 locus. Journal of Immunology 2005, 175(1):469-477.
18. Ma W., Lim W., Gee K., Aucoin S., Nandan D., Kozlowski M., Diaz-Mitoma F., Kumar A. The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages. Journal of Biological Chemistry 2001, 276(17):13664-13674.
19. Malur A., Mccoy A.J., Arce S., Barna B.P., Kavuru M.S., Malur A.G., Thomassen M.J. Deletion of PPAR gamma in alveolar macrophages is associated with a Th-1 pulmonary inflammatory response. Journal of Immunology 2009, 182(9):5816-5822.
20. Michalik L., Desvergne B., Wahli W. Peroxisome-proliferator-activated receptors and cancers: complex stories. Nature Reviews Cancer 2004, 4(1):61-70.
21. Michlewska S., Dransfield I., Megson I.L., Rossi A.G. Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro-inflammatory and anti-inflammatory agents: key role for TNF-alpha. FASEB Journal 2009, 23(3):844-854.
22. Moore K.W., de Waal Malefyt R., Coffman R.L., O'Garra A. Interleukin-10 and the interleukin-10 receptor. Annual Review of Immunology 2001, 19:683-765.
23. Murphy L.O., Blenis J. MAPK signal specificity: the right place at the right time. Trends in Biochemical Sciences 2006, 31(5):268-275.
24. Necela B.M., Su W., Thompson E.A. Toll-like receptor 4 mediates cross-talk between peroxisome proliferator-activated receptor gamma and nuclear factor-kappaB in macrophages. Immunology 2008, 125(3):344-358.
25. Notari L., Baladron V., Aroca-Aguilar J.D., Balko N., Heredia R., Meyer C., Notario P.M., Saravanamuthu S., Nueda M.L., Sanchez-Sanchez F., Escribano J., Laborda J., Becerra S.P. Identification of a lipase-linked cell membrane receptor for pigment epithelium-derived factor. Journal of Biological Chemistry 2006, 281(49):38022-38037.
26. Park M.J., Kim H.Y., Kim K., Cheong J. Homeodomain transcription factor CDX1 is required for the transcriptional induction of PPARgamma in intestinal cell differentiation. FEBS Letters 2009, 583(1):29-35.
27. Schmidt S., Moric E., Schmidt M., Sastre M., Feinstein D.L., Heneka M.T. Anti-inflammatory and antiproliferative actions of PPAR-gamma agonists on T lymphocytes derived from MS patients. Journal of Leukocyte Biology 2004, 75(3):478-485.
28. Strassmann G., Patil-Koota V., Finkelman F., Fong M., Kambayashi T. Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2. Journal of Experimental Medicine 1994, 180(6):2365-2370.
29. Thompson P.W., Bayliffe A.I., Warren A.P., Lamb J.R. Interleukin-10 is upregulated by nanomolar rosiglitazone treatment of mature dendritic cells and human CD4+ T cells. Cytokine 2007, 39(3):184-191.
30. Tsao Y.P., Ho T.C., Chen S.L., Cheng H.C. Pigment epithelium-derived factor inhibits oxidative stress-induced cell death by activation of extracellular signal-regulated kinases in cultured retinal pigment epithelial cells. Life Sciences 2006, 79(6):545-550.
31. Urbonaviciute V., Fürnrohr B.G., Meister S., Munoz L., Heyder P., De Marchis F., Bianchi M.E., Kirschning C., Wagner H., Manfredi A.A., Kalden J.R., Schett G., Rovere-Querini P., Herrmann M., Voll R.E. Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE. Journal of Experimental Medicine 2008, 205(13):3007-3018.
32. Wang J.J., Zhang S.X., Mott R., Chen Y., Knapp R.R., Cao W., Ma J.X. Anti-inflammatory effects of pigment epithelium-derived factor in diabetic nephropathy. American Journal of Physiology Renal Physiology 2008, 294(5):F1166-1173.
33. Yabe T., Wilson D., Schwartz J.P. NFkappaB activation is required for the neuroprotective effects of pigment epithelium-derived factor (PEDF) on cerebellar granule neurons. Journal of Biological Chemistry 2001, 276(46):43313-43319.
34. Yafai Y., Lange J., Wiedemann P., Reichenbach A., Eichler W. Pigment epithelium-derived factor acts as an opponent of growth-stimulatory factors in retinal glial-endothelial cell interactions. Glia 2007, 55(6):642-651.
35. Zaichuk T.A., Shroff E.H., Emmanuel R., Filleur S., Nelius T., Volpert O.V. Nuclear factor of activated T cells balances angiogenesis activation and inhibition. Journal of Experimental Medicine 2004, 199(11):1513-1522.
36. Zamiri P., Masli S., Streilein J.W., Taylor A.W. Pigment epithelial growth factor suppresses inflammation by modulating macrophage activation. Investigative Ophthalmology and Visual Science 2006, 47(9):3912-3918.
37. Zaytseva Y.Y., Wang X., Southard R.C., Wallis N.K., Kilgore M.W. Down-regulation of PPARgamma1 suppresses cell growth and induces apoptosis in MCF-7 breast cancer cells. Molecular Cancer 2008, 7:90.
38. Zhang S.X., Wang J.J., Gao G., Shao C., Mott R., Ma J.X. Pigment epithelium-derived factor (PEDF) is an endogenous antiinflammatory factor. FASEB Journal 2006, 20(2):323-345.
39. Zhang S.X., Wang J.J., Gao G., Parke K., Ma J.X. Pigment epithelium-derived factor downregulates vascular endothelial growth factor (VEGF) expression and inhibits VEGF-VEGF receptor 2 binding in diabetic retinopathy. Journal of Molecular Endocrinology 2006, 37(1):1-12.
40. Zhou J., Febbraio M., Wada T., Zhai Y., Kuruba R., He J., Lee J.H., Khadem S., Ren S., Li S., Silverstein R.L., Xie W. Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis. Gastroenterology 2008, 134(2):556-567.