메뉴 건너뛰기




Volumn 14, Issue 7, 2007, Pages 616-626

Pigment epithelium-derived factor overexpression inhibits orthotopic osteosarcoma growth, angiogenesis and metastasis

Author keywords

Angiogenesis; Antitumor; Metastasis; Osteosarcoma; PEDF

Indexed keywords

COLLAGEN TYPE 1; MATRIGEL; PIGMENT EPITHELIUM DERIVED FACTOR; PLASMID DNA;

EID: 34250352217     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/sj.cgt.7701044     Document Type: Article
Times cited : (94)

References (38)
  • 1
    • 33748200448 scopus 로고    scopus 로고
    • 2nd edn. Lippincott-Verlag: Austria
    • Campanacci M. Bone Tumors. 2nd edn. Lippincott-Verlag: Austria, 1999.
    • (1999) Bone Tumors
    • Campanacci, M.1
  • 2
    • 33749915992 scopus 로고
    • Bone tumors: Diagnosis, Treatment and Prognosis
    • 2nd edn, Philadelphia, PA
    • Huvos A. Bone tumors: Diagnosis, Treatment and Prognosis. 2nd edn. WB Saimders: Philadelphia, PA, 1991.
    • (1991) WB Saimders
    • Huvos, A.1
  • 3
    • 33644837672 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy with high-dose Ifosfamide, high-dose methotrexate, cisplatin, and doxorubicin for patients with localized osteosarcoma of the extremity: A joint study by the Italian and Scandinavian Sarcoma Groups
    • Ferrari S, Smeland S, Mercuri M, Bertoni F, Longhi A, Ruggieri P et al. Neoadjuvant chemotherapy with high-dose Ifosfamide, high-dose methotrexate, cisplatin, and doxorubicin for patients with localized osteosarcoma of the extremity: a joint study by the Italian and Scandinavian Sarcoma Groups. J Clin Oncol 2005; 23: 8845-8852.
    • (2005) J Clin Oncol , vol.23 , pp. 8845-8852
    • Ferrari, S.1    Smeland, S.2    Mercuri, M.3    Bertoni, F.4    Longhi, A.5    Ruggieri, P.6
  • 5
    • 0345359019 scopus 로고    scopus 로고
    • A phase II study of cisplatin, ifosfamide and doxorubicin in operable primary, axial skeletal and metastatic osteosarcoma. European osteosarcoma intergroup (EOI)
    • Voute PA, Souhami RL, Nooij M, Somers R, Cortes-Funes H, van der Eijken JW et al. A phase II study of cisplatin, ifosfamide and doxorubicin in operable primary, axial skeletal and metastatic osteosarcoma. European osteosarcoma intergroup (EOI). Ann Oncol 1999; 10: 1211-1218.
    • (1999) Ann Oncol , vol.10 , pp. 1211-1218
    • Voute, P.A.1    Souhami, R.L.2    Nooij, M.3    Somers, R.4    Cortes-Funes, H.5    van der Eijken, J.W.6
  • 7
    • 0024394207 scopus 로고
    • Neuronal differentiation of retinoblastoma cells induced by medium conditioned by human RPE cells
    • Tombran-Tink J, Johnson LV. Neuronal differentiation of retinoblastoma cells induced by medium conditioned by human RPE cells. Invest Ophthalmol Vis Sci 1989; 30: 1700-1707.
    • (1989) Invest Ophthalmol Vis Sci , vol.30 , pp. 1700-1707
    • Tombran-Tink, J.1    Johnson, L.V.2
  • 8
    • 0025772716 scopus 로고
    • PEDF: A pigment epithelium-derived factor with potent neuronal differentiative activity
    • Tombran-Tink J, Chader GG, Johnson LV. PEDF: a pigment epithelium-derived factor with potent neuronal differentiative activity. Exp Eye Res 1991; 53: 411-414.
    • (1991) Exp Eye Res , vol.53 , pp. 411-414
    • Tombran-Tink, J.1    Chader, G.G.2    Johnson, L.V.3
  • 10
    • 33749158265 scopus 로고    scopus 로고
    • PEDF: A potential molecular therapeutic target with multiple anti-cancer activities
    • Ek ET, Dass CR, Choong PF. PEDF: a potential molecular therapeutic target with multiple anti-cancer activities. Trends Mol Med 2006; 12: 497-502.
    • (2006) Trends Mol Med , vol.12 , pp. 497-502
    • Ek, E.T.1    Dass, C.R.2    Choong, P.F.3
  • 11
    • 33745214608 scopus 로고    scopus 로고
    • Decreased pigment epithelium-derived factor expression in human breast cancer progression
    • Cai J, Parr C, Watkins G, Jiang WG, Boulton M. Decreased pigment epithelium-derived factor expression in human breast cancer progression. Clin Cancer Res 2006; 12: 3510-3517.
    • (2006) Clin Cancer Res , vol.12 , pp. 3510-3517
    • Cai, J.1    Parr, C.2    Watkins, G.3    Jiang, W.G.4    Boulton, M.5
  • 12
    • 33749118769 scopus 로고    scopus 로고
    • Expression of pigment epithelial derived factor is reduced in non-small cell lung cancer and is linked to clinical outcome
    • Zhang L, Chen J, Ke Y, Mansel RE, Jiang WG. Expression of pigment epithelial derived factor is reduced in non-small cell lung cancer and is linked to clinical outcome. Int J Mol Med 2006; 17: 937-944.
    • (2006) Int J Mol Med , vol.17 , pp. 937-944
    • Zhang, L.1    Chen, J.2    Ke, Y.3    Mansel, R.E.4    Jiang, W.G.5
  • 13
    • 4143122398 scopus 로고    scopus 로고
    • Decreased pigment epithelium-derived factor is associated with metastatic phenotype in human and rat prostate tumors
    • Halin S, Wikstrom P, Rudolfsson SH, Stattin P, Doll JA, Crawford SE et al. Decreased pigment epithelium-derived factor is associated with metastatic phenotype in human and rat prostate tumors. Cancer Res 2004; 64: 5664-5671.
    • (2004) Cancer Res , vol.64 , pp. 5664-5671
    • Halin, S.1    Wikstrom, P.2    Rudolfsson, S.H.3    Stattin, P.4    Doll, J.A.5    Crawford, S.E.6
  • 14
    • 2442644244 scopus 로고    scopus 로고
    • Expression of pigment epithelium-derived factor decreases liver metastasis and correlates with favorable prognosis for patients with ductal pancreatic adenocarcinoma
    • Uehara H, Miyamoto M, Kato K, Ebihara Y, Kaneko H, Hashimoto H et al. Expression of pigment epithelium-derived factor decreases liver metastasis and correlates with favorable prognosis for patients with ductal pancreatic adenocarcinoma. Cancer Res 2004; 64: 3533-3537.
    • (2004) Cancer Res , vol.64 , pp. 3533-3537
    • Uehara, H.1    Miyamoto, M.2    Kato, K.3    Ebihara, Y.4    Kaneko, H.5    Hashimoto, H.6
  • 15
    • 0344080618 scopus 로고    scopus 로고
    • Loss of pigment epithelium derived factor expression in glioma progression
    • Guan M, Yam HF, Su B, Chan KP, Pang CP, Liu WW et al. Loss of pigment epithelium derived factor expression in glioma progression. J Clin Pathol 2003; 56: 277-282.
    • (2003) J Clin Pathol , vol.56 , pp. 277-282
    • Guan, M.1    Yam, H.F.2    Su, B.3    Chan, K.P.4    Pang, C.P.5    Liu, W.W.6
  • 16
    • 28144453516 scopus 로고    scopus 로고
    • Altered pigment epithelium-derived factor and vascular endothelial growth factor levels in lymphangioma pathogenesis and clinical recurrence
    • Sidle DM, Maddalozzo J, Meier JD, Cornwell M, Stellmach V, Crawford SE. Altered pigment epithelium-derived factor and vascular endothelial growth factor levels in lymphangioma pathogenesis and clinical recurrence. Arch Otolaryngol Head Neck Surg 2005; 131: 990-995.
    • (2005) Arch Otolaryngol Head Neck Surg , vol.131 , pp. 990-995
    • Sidle, D.M.1    Maddalozzo, J.2    Meier, J.D.3    Cornwell, M.4    Stellmach, V.5    Crawford, S.E.6
  • 17
    • 33748312291 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor: A multimodal tumor inhibitor
    • Ek ET, Dass CR, Choong PF. Pigment epithelium-derived factor: a multimodal tumor inhibitor. Mol Cancer Ther 2006; 5: 1641-1646.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1641-1646
    • Ek, E.T.1    Dass, C.R.2    Choong, P.F.3
  • 18
    • 29344440002 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor gene therapy inhibits human pancreatic cancer in mice
    • Hase R, Miyamoto M, Uehara H, Kadoya M, Ebihara Y, Murakami Y et al. Pigment epithelium-derived factor gene therapy inhibits human pancreatic cancer in mice. Clin Cancer Res 2005; 11: 8737-8744.
    • (2005) Clin Cancer Res , vol.11 , pp. 8737-8744
    • Hase, R.1    Miyamoto, M.2    Uehara, H.3    Kadoya, M.4    Ebihara, Y.5    Murakami, Y.6
  • 19
    • 0038240367 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor regulates the vasculature and mass of the prostate and pancreas
    • Doll JA, Stellmach VM, Bouck NP, Bergh AR, Lee C, Abramson LP et al. Pigment epithelium-derived factor regulates the vasculature and mass of the prostate and pancreas. Nat Med 2003; 9: 774-780.
    • (2003) Nat Med , vol.9 , pp. 774-780
    • Doll, J.A.1    Stellmach, V.M.2    Bouck, N.P.3    Bergh, A.R.4    Lee, C.5    Abramson, L.P.6
  • 20
    • 12144285983 scopus 로고    scopus 로고
    • Overexpression of pigment epithelium-derived factor decreases angiogenesis and inhibits the growth of human malignant melanoma cells in vivo
    • Abe R, Shimizu T, Yamagishi S, Shibaki A, Amano S, Inagaki Y et al. Overexpression of pigment epithelium-derived factor decreases angiogenesis and inhibits the growth of human malignant melanoma cells in vivo. Am J Pathol 2004; 164: 1225-1232.
    • (2004) Am J Pathol , vol.164 , pp. 1225-1232
    • Abe, R.1    Shimizu, T.2    Yamagishi, S.3    Shibaki, A.4    Amano, S.5    Inagaki, Y.6
  • 21
    • 0035691657 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor (PEDF) in neuroblastoma: A multifunctional mediator of Schwann cell antitumor activity
    • Crawford SE, Stellmach V, Ranalli M, Huang X, Huang L, Volpert O et al. Pigment epithelium-derived factor (PEDF) in neuroblastoma: a multifunctional mediator of Schwann cell antitumor activity. J Cell Sci 2001; 114: 4421-4428.
    • (2001) J Cell Sci , vol.114 , pp. 4421-4428
    • Crawford, S.E.1    Stellmach, V.2    Ranalli, M.3    Huang, X.4    Huang, L.5    Volpert, O.6
  • 22
    • 33747602349 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor is estrogen sensitive and inhibits the growth of human ovarian cancer and ovarian surface epithelial cells
    • Cheung LW, Au SC, Cheung AN, Ngan HY, Tombran-Tink J, Auersperg N et al. Pigment epithelium-derived factor is estrogen sensitive and inhibits the growth of human ovarian cancer and ovarian surface epithelial cells. Endocrinology 2006; 147: 4179-4191.
    • (2006) Endocrinology , vol.147 , pp. 4179-4191
    • Cheung, L.W.1    Au, S.C.2    Cheung, A.N.3    Ngan, H.Y.4    Tombran-Tink, J.5    Auersperg, N.6
  • 23
    • 0034896298 scopus 로고    scopus 로고
    • The expression of the urokinase plasminogen activator system in metastatic murine osteosarcoma: An in vivo mouse model
    • Fisher JL, Mackie PS, Howard ML, Zhou H, Choong PF. The expression of the urokinase plasminogen activator system in metastatic murine osteosarcoma: an in vivo mouse model. Clin Cancer Res 2001; 7: 1654-1660.
    • (2001) Clin Cancer Res , vol.7 , pp. 1654-1660
    • Fisher, J.L.1    Mackie, P.S.2    Howard, M.L.3    Zhou, H.4    Choong, P.F.5
  • 24
    • 33846651513 scopus 로고    scopus 로고
    • A novel orthotopic murine model provides insights into cellular and molecular characteristics contributing to human osteosarcoma
    • Dass CR, Ek ET, Contreras KG, Choong PF. A novel orthotopic murine model provides insights into cellular and molecular characteristics contributing to human osteosarcoma. Clin Exp Metastasis 2006; 23: 367-380.
    • (2006) Clin Exp Metastasis , vol.23 , pp. 367-380
    • Dass, C.R.1    Ek, E.T.2    Contreras, K.G.3    Choong, P.F.4
  • 25
    • 0030512898 scopus 로고    scopus 로고
    • Quantification of angiogenesis in solid human tumours: An international consensus on the methodology and criteria of evaluation
    • Vermeulen PB, Gasparini G, Fox SB, Toi M, Martin L, McCulloch P et al. Quantification of angiogenesis in solid human tumours: an international consensus on the methodology and criteria of evaluation. Eur J Cancer 1996; 32A: 2474-2484.
    • (1996) Eur J Cancer , vol.32 A , pp. 2474-2484
    • Vermeulen, P.B.1    Gasparini, G.2    Fox, S.B.3    Toi, M.4    Martin, L.5    McCulloch, P.6
  • 26
    • 0037160083 scopus 로고    scopus 로고
    • Mapping the type I collagen-binding site on pigment epithelium-derived factor. Implications for its antiangiogenic activity
    • Meyer C, Notari L, Becerra SP. Mapping the type I collagen-binding site on pigment epithelium-derived factor. Implications for its antiangiogenic activity. J Biol Chem 2002; 277: 45400-45407.
    • (2002) J Biol Chem , vol.277 , pp. 45400-45407
    • Meyer, C.1    Notari, L.2    Becerra, S.P.3
  • 28
    • 0038649218 scopus 로고    scopus 로고
    • Resistance of epiphyseal cartilage to invasion by osteosarcoma is likely to be due to expression of antiangiogenic factors
    • Quan GM, Ojaimi J, Nadesapillai AP, Zhou H, Choong PF. Resistance of epiphyseal cartilage to invasion by osteosarcoma is likely to be due to expression of antiangiogenic factors. Pathobiology 2002; 70: 361-367.
    • (2002) Pathobiology , vol.70 , pp. 361-367
    • Quan, G.M.1    Ojaimi, J.2    Nadesapillai, A.P.3    Zhou, H.4    Choong, P.F.5
  • 29
    • 0036104828 scopus 로고    scopus 로고
    • Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor
    • Volpert OV, Zaichuk T, Zhou W, Reiher F, Ferguson TA, Stuart PM et al. Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor. Nat Med 2002; 8: 349-357.
    • (2002) Nat Med , vol.8 , pp. 349-357
    • Volpert, O.V.1    Zaichuk, T.2    Zhou, W.3    Reiher, F.4    Ferguson, T.A.5    Stuart, P.M.6
  • 30
    • 0028924851 scopus 로고
    • Analysis of EPC-1 growth state-dependent expression, specificity, and conservation of related sequences
    • Pignolo RJ, Rotenberg MO, Cristofalo VJ. Analysis of EPC-1 growth state-dependent expression, specificity, and conservation of related sequences. J Cell Physiol 1995; 162: 110-118.
    • (1995) J Cell Physiol , vol.162 , pp. 110-118
    • Pignolo, R.J.1    Rotenberg, M.O.2    Cristofalo, V.J.3
  • 31
    • 20444462032 scopus 로고    scopus 로고
    • Two functional epitopes of pigment epithelial-derived factor block angiogenesis and induce differentiation in prostate cancer
    • Filleur S, Volz K, Nelius T, Mirochnik Y, Huang H, Zaichuk TA et al. Two functional epitopes of pigment epithelial-derived factor block angiogenesis and induce differentiation in prostate cancer. Cancer Res 2005; 65: 5144-5152.
    • (2005) Cancer Res , vol.65 , pp. 5144-5152
    • Filleur, S.1    Volz, K.2    Nelius, T.3    Mirochnik, Y.4    Huang, H.5    Zaichuk, T.A.6
  • 32
    • 0034129118 scopus 로고    scopus 로고
    • Recent advances in research on multistage tumorigenesis
    • Compagni A, Christofori G. Recent advances in research on multistage tumorigenesis. Br J Cancer 2000; 83: 1-5.
    • (2000) Br J Cancer , vol.83 , pp. 1-5
    • Compagni, A.1    Christofori, G.2
  • 33
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 34
    • 0026639806 scopus 로고
    • Angiogenesis
    • Folkman J, Shing Y. Angiogenesis. J Biol Chem 1992; 267: 10931-10934.
    • (1992) J Biol Chem , vol.267 , pp. 10931-10934
    • Folkman, J.1    Shing, Y.2
  • 35
    • 33645635929 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1
    • Cai J, Jiang WG, Grant MB, Boulton M. Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1. J Biol Chem 2006; 281: 3604-3613.
    • (2006) J Biol Chem , vol.281 , pp. 3604-3613
    • Cai, J.1    Jiang, W.G.2    Grant, M.B.3    Boulton, M.4
  • 36
    • 33750737315 scopus 로고    scopus 로고
    • Does the degree of intratumoural microvessel density and VEGF expression have prognostic significance in osteosarcoma?
    • Ek ET, Ojaimi J, Kitagawa Y, Choong PF. Does the degree of intratumoural microvessel density and VEGF expression have prognostic significance in osteosarcoma? Oncol Rep 2006; 16: 17-23.
    • (2006) Oncol Rep , vol.16 , pp. 17-23
    • Ek, E.T.1    Ojaimi, J.2    Kitagawa, Y.3    Choong, P.F.4
  • 37
    • 2342566543 scopus 로고    scopus 로고
    • Inhibition of glioma invasion by overexpression of pigment epithelium-derived factor
    • Guan M, Pang CP, Yam HF, Cheung KF, Liu WW, Lu Y. Inhibition of glioma invasion by overexpression of pigment epithelium-derived factor. Cancer Gene Ther 2004; 11: 325-332.
    • (2004) Cancer Gene Ther , vol.11 , pp. 325-332
    • Guan, M.1    Pang, C.P.2    Yam, H.F.3    Cheung, K.F.4    Liu, W.W.5    Lu, Y.6
  • 38
    • 0032902481 scopus 로고    scopus 로고
    • Overexpression of matrix metalloproteinase (MMP)-9 correlates with metastatic potency of spontaneous and 4-hydroxyaminoquinoline 1-oxide (4-HAQO)-induced transplantable osteosarcomas in rats
    • Kido A, Tsutsumi M, Iki K, Takahama M, Tsujiuchi T, Morishita T et al. Overexpression of matrix metalloproteinase (MMP)-9 correlates with metastatic potency of spontaneous and 4-hydroxyaminoquinoline 1-oxide (4-HAQO)-induced transplantable osteosarcomas in rats. Cancer Lett 1999; 137: 209-216.
    • (1999) Cancer Lett , vol.137 , pp. 209-216
    • Kido, A.1    Tsutsumi, M.2    Iki, K.3    Takahama, M.4    Tsujiuchi, T.5    Morishita, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.