-
1
-
-
0027278557
-
Instability and decay of the primary structure of DNA
-
Lindahl T (1993) Instability and decay of the primary structure of DNA. Nature 362(6422):709-715.
-
(1993)
Nature
, vol.362
, Issue.6422
, pp. 709-715
-
-
Lindahl, T.1
-
2
-
-
23844558266
-
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine
-
Wallace DC (2005) A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine. Annu Rev Genet 39:359-407.
-
(2005)
Annu Rev Genet
, vol.39
, pp. 359-407
-
-
Wallace, D.C.1
-
4
-
-
10944251591
-
Repair and genetic consequences of endogenous DNA base damage in mammalian cells
-
Barnes DE, Lindahl T (2004) Repair and genetic consequences of endogenous DNA base damage in mammalian cells. Annu Rev Genet 38:445-476.
-
(2004)
Annu Rev Genet
, vol.38
, pp. 445-476
-
-
Barnes, D.E.1
Lindahl, T.2
-
5
-
-
0030008052
-
Superoxide production in rat hippo-campal neurons: Selective imaging with hydroethidine
-
Bindokas VP, Jordán J, Lee CC, Miller RJ (1996) Superoxide production in rat hippo-campal neurons: Selective imaging with hydroethidine. J Neurosci 16(4):1324-1336.
-
(1996)
J Neurosci
, vol.16
, Issue.4
, pp. 1324-1336
-
-
Bindokas, V.P.1
Jordán, J.2
Lee, C.C.3
Miller, R.J.4
-
6
-
-
33751072935
-
Bioenergetics and the formation of mitochondrial reactive oxygen species
-
Adam-Vizi V, Chinopoulos C (2006) Bioenergetics and the formation of mitochondrial reactive oxygen species. Trends Pharmacol Sci 27(12):639-645.
-
(2006)
Trends Pharmacol Sci
, vol.27
, Issue.12
, pp. 639-645
-
-
Adam-Vizi, V.1
Chinopoulos, C.2
-
7
-
-
0036012789
-
ATM deficiency and oxidative stress: A new dimension of defective response to DNA damage
-
Barzilai A, Rotman G, Shiloh Y (2002) ATM deficiency and oxidative stress: A new dimension of defective response to DNA damage. DNA Repair (Amst) 1(1):3-25.
-
(2002)
DNA Repair (Amst)
, vol.1
, Issue.1
, pp. 3-25
-
-
Barzilai, A.1
Rotman, G.2
Shiloh, Y.3
-
8
-
-
0035902108
-
Genome maintenance mechanisms for preventing cancer
-
Hoeijmakers JH (2001) Genome maintenance mechanisms for preventing cancer. Nature 411(6835):366-374.
-
(2001)
Nature
, vol.411
, Issue.6835
, pp. 366-374
-
-
Hoeijmakers, J.H.1
-
9
-
-
84863895758
-
Brain and muscle arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis
-
Geyfman M, et al. (2012) Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis. Proc Natl Acad Sci USA 109(29):11758-11763.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.29
, pp. 11758-11763
-
-
Geyfman, M.1
-
10
-
-
84872783004
-
Comparative analysis of bat genomes provides insight into the evolution of flight and immunity
-
Zhang G, et al. (2013) Comparative analysis of bat genomes provides insight into the evolution of flight and immunity. Science 339(6118):456-460.
-
(2013)
Science
, vol.339
, Issue.6118
, pp. 456-460
-
-
Zhang, G.1
-
11
-
-
84886812954
-
The nexus of chromatin regulation and intermediary metabolism
-
Gut P, Verdin E (2013) The nexus of chromatin regulation and intermediary metabolism. Nature 502(7472):489-498.
-
(2013)
Nature
, vol.502
, Issue.7472
, pp. 489-498
-
-
Gut, P.1
Verdin, E.2
-
13
-
-
77956223101
-
Calcium and mitochondrial reactive oxygen species generation: How to read the facts
-
Adam-Vizi V, Starkov AA (2010) Calcium and mitochondrial reactive oxygen species generation: How to read the facts. J Alzheimers Dis 20(Suppl 2):S413-S426.
-
(2010)
J Alzheimers Dis
, vol.20
, pp. S413-S426
-
-
Adam-Vizi, V.1
Starkov, A.A.2
-
14
-
-
0037413368
-
Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice
-
de Waard H, et al. (2003) Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice. DNA Repair (Amst) 2(1):13-25.
-
(2003)
DNA Repair (Amst)
, vol.2
, Issue.1
, pp. 13-25
-
-
De Waard, H.1
-
15
-
-
33846923284
-
Retinal degeneration and ionizing radiation hypersensitivity in a mouse model for cockayne syndrome
-
Gorgels TG, et al. (2007) Retinal degeneration and ionizing radiation hypersensitivity in a mouse model for Cockayne syndrome. Mol Cell Biol 27(4):1433-1441.
-
(2007)
Mol Cell Biol
, vol.27
, Issue.4
, pp. 1433-1441
-
-
Gorgels, T.G.1
-
16
-
-
29244483920
-
Host cell reactivation of plasmids containing oxidative DNA lesions is defective in cockayne syndrome but normal in UV-sensitive syndrome fibroblasts
-
Spivak G, Hanawalt PC (2006) Host cell reactivation of plasmids containing oxidative DNA lesions is defective in Cockayne syndrome but normal in UV-sensitive syndrome fibroblasts. DNA Repair (Amst) 5(1):13-22.
-
(2006)
DNA Repair (Amst)
, vol.5
, Issue.1
, pp. 13-22
-
-
Spivak, G.1
Hanawalt, P.C.2
-
18
-
-
84860340909
-
Photosensitivity syndrome brings to light a new transcription-coupled DNA repair cofactor
-
Cleaver JE (2012) Photosensitivity syndrome brings to light a new transcription-coupled DNA repair cofactor. Nat Genet 44(5):477-478.
-
(2012)
Nat Genet
, vol.44
, Issue.5
, pp. 477-478
-
-
Cleaver, J.E.1
-
19
-
-
70350065725
-
Disorders of nucleotide excision repair: The genetic and molecular basis of heterogeneity
-
Cleaver JE, Lam ET, Revet I (2009) Disorders of nucleotide excision repair: The genetic and molecular basis of heterogeneity. Nat Rev Genet 10(11):756-768.
-
(2009)
Nat Rev Genet
, vol.10
, Issue.11
, pp. 756-768
-
-
Cleaver, J.E.1
Lam, E.T.2
Revet, I.3
-
20
-
-
84860336243
-
Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair
-
Zhang X, et al. (2012) Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair. Nat Genet 44(5):593-597.
-
(2012)
Nat Genet
, vol.44
, Issue.5
, pp. 593-597
-
-
Zhang, X.1
-
21
-
-
84860330462
-
UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair
-
Schwertman P, et al. (2012) UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair. Nat Genet 44(5):598-602.
-
(2012)
Nat Genet
, vol.44
, Issue.5
, pp. 598-602
-
-
Schwertman, P.1
-
22
-
-
84860330507
-
Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair
-
Nakazawa Y, et al. (2012) Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair. Nat Genet 44:586-592.
-
(2012)
Nat Genet
, vol.44
, pp. 586-592
-
-
Nakazawa, Y.1
-
23
-
-
0019857509
-
A new human photosensitive subject with a defect in the recovery of DNA synthesis after ultraviolet-light irradiation
-
Fujiwara Y, Ichihashi M, Kano Y, Goto K, Shimizu K (1981) A new human photosensitive subject with a defect in the recovery of DNA synthesis after ultraviolet-light irradiation. J Invest Dermatol 77(3):256-263.
-
(1981)
J Invest Dermatol
, vol.77
, Issue.3
, pp. 256-263
-
-
Fujiwara, Y.1
Ichihashi, M.2
Kano, Y.3
Goto, K.4
Shimizu, K.5
-
24
-
-
84860883265
-
An altered redox balance mediates the hypersensitivity of cockayne syndrome primary fibroblasts to oxidative stress
-
Pascucci B, et al. (2012) An altered redox balance mediates the hypersensitivity of Cockayne syndrome primary fibroblasts to oxidative stress. Aging Cell 11(3):520-529.
-
(2012)
Aging Cell
, vol.11
, Issue.3
, pp. 520-529
-
-
Pascucci, B.1
-
25
-
-
84867431394
-
KIAA1530 protein is recruited by cockayne syndrome complementation group protein A (CSA) to participate in transcription-coupled repair (TCR)
-
Fei J, Chen J (2012) KIAA1530 protein is recruited by Cockayne syndrome complementation group protein A (CSA) to participate in transcription-coupled repair (TCR). J Biol Chem 287(42):35118-35126.
-
(2012)
J Biol Chem
, vol.287
, Issue.42
, pp. 35118-35126
-
-
Fei, J.1
Chen, J.2
-
26
-
-
67649800742
-
NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation
-
Brennan AM, et al. (2009) NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation. Nat Neurosci 12(7):857-863.
-
(2009)
Nat Neurosci
, vol.12
, Issue.7
, pp. 857-863
-
-
Brennan, A.M.1
-
27
-
-
0347479231
-
Oxidative stress is responsible for deficient survival and dendritogenesis in purkinje neurons from ataxia-telangiectasia mutated mutant mice
-
Chen P, et al. (2003) Oxidative stress is responsible for deficient survival and dendritogenesis in purkinje neurons from ataxia-telangiectasia mutated mutant mice. J Neurosci 23(36):11453-11460.
-
(2003)
J Neurosci
, vol.23
, Issue.36
, pp. 11453-11460
-
-
Chen, P.1
-
28
-
-
71049171763
-
Rapid flow cytometric method for measuring senescence associated beta-galactosidase activity in human fibroblasts
-
Noppe G, et al. (2009) Rapid flow cytometric method for measuring senescence associated beta-galactosidase activity in human fibroblasts. Cytometry A 75(11):910-916.
-
(2009)
Cytometry A
, vol.75
, Issue.11
, pp. 910-916
-
-
Noppe, G.1
-
29
-
-
84878018097
-
Conceptual developments in the causes of cockayne syndrome
-
Cleaver JE, Bezrookove V, Revet I, Huang EJ (2013) Conceptual developments in the causes of Cockayne syndrome. Mech Ageing Dev 134(5-6):284-290.
-
(2013)
Mech Ageing Dev
, vol.134
, Issue.5-6
, pp. 284-290
-
-
Cleaver, J.E.1
Bezrookove, V.2
Revet, I.3
Huang, E.J.4
-
30
-
-
0031844311
-
XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage
-
Masson M, et al. (1998) XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage. Mol Cell Biol 18(6):3563-3571.
-
(1998)
Mol Cell Biol
, vol.18
, Issue.6
, pp. 3563-3571
-
-
Masson, M.1
-
31
-
-
33645321089
-
Mechanism of DNA damage induced by bromate differs from general types of oxidative stress
-
Kawanishi S, Murata M (2006) Mechanism of DNA damage induced by bromate differs from general types of oxidative stress. Toxicology 221(2-3):172-178.
-
(2006)
Toxicology
, vol.221
, Issue.2-3
, pp. 172-178
-
-
Kawanishi, S.1
Murata, M.2
-
32
-
-
34347352111
-
The role of CSA in the response to oxidative DNA damage in human cells
-
D'Errico M, et al. (2007) The role of CSA in the response to oxidative DNA damage in human cells. Oncogene 26(30):4336-4343.
-
(2007)
Oncogene
, vol.26
, Issue.30
, pp. 4336-4343
-
-
D'Errico, M.1
-
33
-
-
84898023373
-
PINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncoupling
-
Morais VA, et al. (2014) PINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncoupling. Science 344(6180):203-207.
-
(2014)
Science
, vol.344
, Issue.6180
, pp. 203-207
-
-
Morais, V.A.1
-
34
-
-
84861749572
-
Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy
-
Scheibye-Knudsen M, et al. (2012) Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy. J Exp Med 209(4):855-869.
-
(2012)
J Exp Med
, vol.209
, Issue.4
, pp. 855-869
-
-
Scheibye-Knudsen, M.1
-
35
-
-
84858649212
-
Dysmyelination not demyelination causes neurological symptoms in preweaned mice in a murine model of cockayne syndrome
-
Revet I, Feeney L, Tang AA, Huang EJ, Cleaver JE (2012) Dysmyelination not demyelination causes neurological symptoms in preweaned mice in a murine model of Cockayne syndrome. Proc Natl Acad Sci USA 109(12):4627-4632.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.12
, pp. 4627-4632
-
-
Revet, I.1
Feeney, L.2
Tang, A.A.3
Huang, E.J.4
Cleaver, J.E.5
-
36
-
-
33846613301
-
Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient cockayne syndrome mice
-
Laposa RR, Huang EJ, Cleaver JE (2007) Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice. Proc Natl Acad Sci USA 104(4):1389-1394.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.4
, pp. 1389-1394
-
-
Laposa, R.R.1
Huang, E.J.2
Cleaver, J.E.3
-
37
-
-
77958191599
-
ATM activation by oxidative stress
-
Guo Z, Kozlov S, Lavin MF, Person MD, Paull TT (2010) ATM activation by oxidative stress. Science 330(6003):517-521.
-
(2010)
Science
, vol.330
, Issue.6003
, pp. 517-521
-
-
Guo, Z.1
Kozlov, S.2
Lavin, M.F.3
Person, M.D.4
Paull, T.T.5
-
38
-
-
13444273546
-
DNA repair: The importance of phosphorylating histone H2AX
-
Lowndes NF, Toh GW-L (2005) DNA repair: The importance of phosphorylating histone H2AX. Curr Biol 15(3):R99-R102.
-
(2005)
Curr Biol
, vol.15
, Issue.3
, pp. R99-R102
-
-
Lowndes, N.F.1
Toh, G.W.-L.2
-
39
-
-
79957705193
-
Functional relevance of the histone gammaH2Ax in the response to DNA damaging agents
-
Revet I, et al. (2011) Functional relevance of the histone gammaH2Ax in the response to DNA damaging agents. Proc Natl Acad Sci USA 108(21):8663-8667.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.21
, pp. 8663-8667
-
-
Revet, I.1
-
40
-
-
77951026398
-
A minority of foci or pan-nuclear apoptotic staining of gammaH2AX in the S phase after UV damage contain DNA double-strand breaks
-
de Feraudy S, Revet I, Bezrookove V, Feeney L, Cleaver JE (2010) A minority of foci or pan-nuclear apoptotic staining of gammaH2AX in the S phase after UV damage contain DNA double-strand breaks. Proc Natl Acad Sci USA 107(15):6870-6875.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.15
, pp. 6870-6875
-
-
De Feraudy, S.1
Revet, I.2
Bezrookove, V.3
Feeney, L.4
Cleaver, J.E.5
-
41
-
-
1342328151
-
Reactive oxygen species derived from the mitochondrial respiratory chain are not responsible for the basal levels of oxidative base modifications observed in nuclear DNA of mammalian cells
-
Hoffmann S, Spitkovsky D, Radicella JP, Epe B, Wiesner RJ (2004) Reactive oxygen species derived from the mitochondrial respiratory chain are not responsible for the basal levels of oxidative base modifications observed in nuclear DNA of mammalian cells. Free Radic Biol Med 36(6):765-773.
-
(2004)
Free Radic Biol Med
, vol.36
, Issue.6
, pp. 765-773
-
-
Hoffmann, S.1
Spitkovsky, D.2
Radicella, J.P.3
Epe, B.4
Wiesner, R.J.5
-
42
-
-
0034636004
-
Removal of oxygen free-radical-induced 5',8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells
-
Kuraoka I, et al. (2000) Removal of oxygen free-radical-induced 5',8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells. Proc Natl Acad Sci USA 97(8):3832-3837.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.8
, pp. 3832-3837
-
-
Kuraoka, I.1
-
43
-
-
34247148895
-
The case for 8,5'-cyclopurine-2'-deoxynucleosides as endogenous DNA lesions that cause neurodegeneration in xeroderma pigmentosum
-
Brooks PJ (2007) The case for 8,5'-cyclopurine-2'-deoxynucleosides as endogenous DNA lesions that cause neurodegeneration in xeroderma pigmentosum. Neuroscience 145(4):1407-1417.
-
(2007)
Neuroscience
, vol.145
, Issue.4
, pp. 1407-1417
-
-
Brooks, P.J.1
-
44
-
-
0032496215
-
Biochemical and biological characterization of wild-type and ATPase-deficient cockayne syndrome B repair protein
-
Citterio E, et al. (1998) Biochemical and biological characterization of wild-type and ATPase-deficient Cockayne syndrome B repair protein. J Biol Chem 273(19):11844-11851.
-
(1998)
J Biol Chem
, vol.273
, Issue.19
, pp. 11844-11851
-
-
Citterio, E.1
-
45
-
-
59049107421
-
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
-
Van Raamsdonk CD, et al. (2009) Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. Nature 457(7229):599-602.
-
(2009)
Nature
, vol.457
, Issue.7229
, pp. 599-602
-
-
Van Raamsdonk, C.D.1
|