Hydrolysates of sheep cheese whey as a source of bioactive peptides with antioxidant and angiotensin-converting enzyme inhibitory activities

Peptides

Volumn 61, Issue , 2014, Pages 48-55

  Corrêa, Ana Paula Folmer ^a   Daroit, Daniel Joner ^b   Fontoura, Roberta ^a   Meira, Stela Maris Meister ^a   Segalin, Jeferson ^a   Brandelli, Adriano ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE   (Brazil)

^b UNIVERSIDADE FEDERAL DA FRONTEIRA SUL   (Brazil)

Author keywords

Antihypertensive activity; Antioxidant activity; Bioactive peptides; Cheese whey; Microbial protease; Protein hydrolysates

Indexed keywords

AMINO ACID; ANTIOXIDANT; BETA LACTOGLOBULIN; DIPEPTIDYL CARBOXYPEPTIDASE; PROTEIN HYDROLYSATE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; MILK PROTEIN; PEPTIDE;

ARTICLE; BACILLUS; BIOLOGICAL ACTIVITY; BIOTECHNOLOGICAL PROCEDURES; CHEESE; DAIRY PRODUCT; ENZYME INHIBITION; FOOD PROCESSING; HYDROLYSIS; NONHUMAN; SHEEP CHEESE WHEY; ANALYSIS; ANIMAL; CHEMISTRY; HUMAN; METABOLISM; SHEEP;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ANTIOXIDANTS; BACILLUS; CHEESE; HUMANS; MILK PROTEINS; PEPTIDES; SHEEP;

EID: 84907187788     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2014.09.001     Document Type: Article

References (43)

1. R. Adjonu, G. Doran, P. Torley, and S. Agboola Screening of whey protein isolate hydrolysates for their dual functionality: influence of heat pre-treatment and enzyme specificity Food Chem 136 2013 1435 1443
2. I. Chelh, P. Gatellier, and V. Santé-Lhoutellier Technical note: a simplified procedure for myofibril hydrophobicity determination Meat Sci 74 2006 681 683
3. M.M. Contreras, B. Hernández-Ledesma, L. Amigo, P.J. Martín-Álvarez, and I. Recio Production of antioxidant hydrolyzates from a whey protein concentrate with thermolysin: optimization by response surface methodology LWT Food Sci Technol 44 2011 9 15
4. V. Conway, S.F. Gauthier, and Y. Pouliot Antioxidant activities of buttermilk proteins, whey proteins, and their enzymatic hydrolysates J Agric Food Chem 61 2013 364 372
5. A.P.F. Corrêa, D.J. Daroit, and A. Brandelli Characterization of a keratinase produced by Bacillus sp. P7 isolated from an Amazonian environment Int Biodeterior Biodegrad 64 2010 1 6
6. A.P.F. Corrêa, D.J. Daroit, J.G. Coelho, S.M.M. Meira, F.C. Lopes, and J. Segalin Antioxidant, antihypertensive and antimicrobial properties of ovine milk caseinate hydrolyzed with a microbial protease J Sci Food Agric 91 2011 2247 2254
7. E.L. Costa, J.A.R. Gontijo, and F.M. Netto Effect of heat and enzymatic treatment on the antihypertensive activity of whey protein hydrolysates Int Dairy J 17 2007 632 640
8. N. Creusot, H. Gruppen, G.A. van Koningsveld, C.G. de Kruif, and A.G.J. Voragen Peptide-peptide and protein-peptide interactions in mixtures of whey protein isolate and whey protein isolate hydrolysates Int Dairy J 16 2006 840 849
9. D.W. Cushman, and H.S. Cheung Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung Biochem Pharmacol 20 1971 1637 1648
10. D.J. Daroit, A.P.F. Corrêa, M.M. Canales, J.G. Coelho, M.E. Hidalgo, and D.M. Tichota Physicochemical properties and biological activities of ovine caseinate hydrolysates Dairy Sci Technol 92 2012 335 351
11. D. Doucet, S.F. Gauthier, D.E. Otter, and E.A. Foegeding Enzyme-induced gelation of extensively hydrolyzed whey proteins by Alcalase: comparison with the plastein reaction and characterization of interactions J Agric Food Chem 51 2003 6036 6042
12. A. Dryáková, A. Pihlanto, P. Marnila, L. Eurda, and H.J.T. Korhonen Antioxidant properties of whey protein hydrolysates as measured by three methods Eur Food Res Technol 230 2010 865 874
13. P.D. Duh, Y.Y. Tu, and G.C. Yen Antioxidant activity of water extract of Harng Jyur (Chrysanthemum morifolium Ramat) LWT Food Sci Technol 32 1999 269 277
14. R.J. FitzGerald, B.A. Murray, and D.J. Walsh Hypotensive peptides from milk proteins J Nutr 134 2004 S980 S988
15. J.A. Gómez-Ruiz, I. López-Expósito, A. Pihlanto, M. Ramos, and I. Recio Antioxidant activity of ovine casein hydrolysates: identification of active peptides by HPLC-MS/MS Eur Food Res Technol 227 2008 1061 1067
16. M.I. González Siso The biotechnological utilization of cheese whey: a review Bioresour Technol 57 1996 1 11
17. B. Hernández-Ledesma, A. Dávalos, B. Bartolomé, and L. Amigo Preparation of antioxidant enzymatic hydrolysates from α-lactalbumin and β-lactoglobulin. Identification of active peptides by HPLC-MS/MS J Agric Food Chem 53 2005 588 593
18. S. Khantaphant, S. Benjakul, and H. Kishimura Antioxidative and ACE inhibitory activities of protein hydrolysates from the muscle of brownstripe red snapper prepared using pyloric caeca and commercial proteases Process Biochem 46 2011 318 327
19. V. Klompong, S. Benjakul, D. Kantachote, and F. Shahidi Antioxidative activity and functional properties of protein hydrolysate of yellow stripe trevally (Selaroides leptolepis) as influenced by the degree of hydrolysis and enzyme type Food Chem 102 2007 1317 1327
20. B. Kong, X. Peng, Y.L. Xiong, and X. Zhao Protection of lung fibroblast MRC-5 cells against hydrogen peroxide-induced oxidative damage by 0.1-2.8 kDa antioxidative peptides isolated from whey protein hydrolysate Food Chem 135 2012 540 547
21. J. Kyte, and R.F. Doolittle A simple method for displaying the hydropathic character of a protein J Mol Biol 157 1982 105 132
22. R. López-Fandiño, J. Otte, and J. van Camp Physiological, chemical and technological aspects of milk-protein-derived peptides with antihypertensive and ACE-inhibitory activity Int Dairy J 16 2006 1277 1293
23. O.H. Lowry, N.J. Rosebrough, A.L. Farr, and R.J. Randall Protein measurement with the Folin phenol reagent J Biol Chem 193 1951 267 275
24. A.R. Madureira, T. Tavares, A.M.P. Gomes, M.E. Pintado, and F.X. Malcata Physiological properties of bioactive peptides obtained from whey proteins J Dairy Sci 93 2011 437 455
25. S. Moore, and W.H. Stein A modifed ninhidrin reagent for the photometric determination of amino acids and related compounds J Biol Chem 211 1957 907 913
26. M.M. Mullally, H. Meisel, and R.J. FitzGerald Angiotensin-I-converting enzyme inhibitory activities of gastric and pancreatic proteinase digests of whey proteins Int Dairy J 7 1997 299 303
27. J. Otte, Z.Y. Ju, M. Færgemand, S.B. Lomholt, and K.B. Qvist Protease-induced aggregation and gelation of whey proteins J Food Sci 61 1996 911 916
28. J. Otte, S.M. Shalaby, M. Zakora, A.H. Pripp, and S.A. El-Shabrawy Angiotensin-converting enzyme inhibitory activity of milk protein hydrolysates: effect of substrate, enzyme and time of hydrolysis Int Dairy J 17 2007 488 503
29. Y.W. Park, M. Juárez, M. Ramos, and G.F.W. Haenlein Physico-chemical characteristics of goat and sheep milk Small Rumin Res 68 2007 88 113
30. X. Peng, B. Kong, X. Xia, and Q. Liu Reducing and radical-scavenging activities of whey protein hydrolysates prepared with Alcalase Int Dairy J 20 2010 360 365
31. M. Phelan, A. Aherne, R.J. FitzGerald, and N.M. O'Brien Casein-derived bioactive peptides: biological effects, industrial uses, safety aspects and regulatory status Int Dairy J 19 2009 643 654
32. A. Pihlanto-Leppälä, T. Rokka, H. Korhonen, and I. Angiotensin converting enzyme inhibitory peptides derived from bovine milk proteins Int Dairy J 8 1998 325 331
33. A.R. Prazeres, F. Carvalho, and J. Rivas Cheese whey management: a review J Environ Manag 110 2012 48 68
34. R. Re, N. Pellegrini, A. Proteggente, A. Pannala, M. Yang, and C. Rice-Evans Antioxidant activity applying an improved ABTS radical cation decolorization assay Free Radic Biol Med 26 1999 1231 1237
35. K. Rossini, C.P.Z. Noreña, F. Cladera-Olivera, and A. Brandelli Casein peptides with inhibitory activity on lipid oxidation in beef homogenates and mechanically deboned poultry meat LWT Food Sci Technol 42 2009 862 867
36. A. Roy, A. Kucukural, and Y. Zhang I-TASSER: a unified platform for automated protein structure and function prediction Nat Protoc 5 2010 725 738
37. B.H. Sarmadi, and A. Ismail Antioxidative peptides from food proteins: a review Peptides 31 2010 1949 1956
38. R. Sinha, C. Radha, J. Prakash, and P. Kaul Whey protein hydrolysate: functional properties, nutritional quality and utilization in beverage formulation Food Chem 101 2007 1484 1491
39. S.Z. Tang, J.P. Kerry, D. Sheehan, and D.J. Buckley Antioxidative mechanisms of tea catechins in chicken meat systems Food Chem 76 2002 45 51
40. T. Tavares, M.M. Contreras, M. Amorim, M. Pintado, I. Recio, and F.X. Malcata Novel whey-derived peptides with inhibitory effect against angiotensin-converting enzyme: in vitro effect and stability to gastrointestinal enzymes Peptides 32 2011 1013 1019
41. T.G. Tavares, K.M. Monteiro, A. Possenti, M.E. Pintado, J.E. Carvalho, and F.X. Malcata Antiulcerogenic activity of peptide concentrates obtained from hydrolysis of whey proteins by proteases from Cynara cardunculus Int Dairy J 21 2011 934 939
42. L. Zhang, J. Li, and K. Zhou Chelating and radical scavenging activities of soy protein hydrolysates prepared from microbial proteases and their effect on meat lipid peroxidation Bioresour Technol 101 2010 2084 2089
43. Q.X. Zhang, Y.F. Ling, Z. Sun, L. Zhang, H.X. Yu, and S.M. Kamau Protective effect of whey protein hydrolysates against hydrogen peroxide-induced oxidative stress on PC12 cells Biotechnol Lett 34 2012 2001 2006